Pub Date : 2023-09-20DOI: 10.34257/gjmrbvol23is3pg5
Amanda Gomes Quiroga, Jose Pereira da Silva Filho, Joaquim Lucas Silva Cardoso, Valter Oliveira da Silva, Ana Beatriz de Matos Berg Abrantes, Rebeca Mendes Peres, Fabiana Caroline Coelho Carvalho Firme, Isabella Menezes Batista, Ana Laura Passos de Magalhães, Ulisses Tomaz Monteiro, Bruna Daher Fonseca, Marina Mota de Oliveira Madruga, Caio Lopes Oliveira, Rayssa Blenda Martins, Victor de Oliveira Bessa, Maria Alice Silva Vasconcelos, Pollyane Vieira de Almeida, Dra. Aline de Amorim Duarte
Introduction: It's important to comprehend the key concepts of chronic ligament injuries to the ankle, which occur when there is deterioration or weakening and can result from recurrent or untreated trauma (AMODIO, 2013). Chronic ligament damage typically results from frequent ankle sprains. Ligaments are fibrous tissues that connect bones and provide stability for joints. In the ankle, the ligaments most commonly affected are the anterior talofibular ligament and the calcaneofibular ligament.
{"title":"Chronic Ankle Ligament Injury and its Clinical Management, A Literature Review","authors":"Amanda Gomes Quiroga, Jose Pereira da Silva Filho, Joaquim Lucas Silva Cardoso, Valter Oliveira da Silva, Ana Beatriz de Matos Berg Abrantes, Rebeca Mendes Peres, Fabiana Caroline Coelho Carvalho Firme, Isabella Menezes Batista, Ana Laura Passos de Magalhães, Ulisses Tomaz Monteiro, Bruna Daher Fonseca, Marina Mota de Oliveira Madruga, Caio Lopes Oliveira, Rayssa Blenda Martins, Victor de Oliveira Bessa, Maria Alice Silva Vasconcelos, Pollyane Vieira de Almeida, Dra. Aline de Amorim Duarte","doi":"10.34257/gjmrbvol23is3pg5","DOIUrl":"https://doi.org/10.34257/gjmrbvol23is3pg5","url":null,"abstract":"Introduction: It's important to comprehend the key concepts of chronic ligament injuries to the ankle, which occur when there is deterioration or weakening and can result from recurrent or untreated trauma (AMODIO, 2013). Chronic ligament damage typically results from frequent ankle sprains. Ligaments are fibrous tissues that connect bones and provide stability for joints. In the ankle, the ligaments most commonly affected are the anterior talofibular ligament and the calcaneofibular ligament.","PeriodicalId":93101,"journal":{"name":"Global journal of medical research","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136313988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-23DOI: 10.34257/gjmrevol23is2pg11
Anu Anna George, M. Isac
Miliary tuberculosis is usually seen in pregnant women with a compromised immune system. Recent studies have speculated a plausible immune dysregulation for several months following a COVID-19 infection. We report the case of a pregnant women who had COVID infection in the first trimester and miliary tuberculosis with ARDS in the third trimester. We presume that the onset of tuberculosis as disseminated disease could be due to a weakened immune system following COVID-19 infection and we hope that this case could shed some light on the risk for infections during the post – covid phase in pregnancy.
{"title":"Miliary Tuberculosis in Pregnancy in the Post Covid Phase– A Case Report","authors":"Anu Anna George, M. Isac","doi":"10.34257/gjmrevol23is2pg11","DOIUrl":"https://doi.org/10.34257/gjmrevol23is2pg11","url":null,"abstract":"Miliary tuberculosis is usually seen in pregnant women with a compromised immune system. Recent studies have speculated a plausible immune dysregulation for several months following a COVID-19 infection. We report the case of a pregnant women who had COVID infection in the first trimester and miliary tuberculosis with ARDS in the third trimester. We presume that the onset of tuberculosis as disseminated disease could be due to a weakened immune system following COVID-19 infection and we hope that this case could shed some light on the risk for infections during the post – covid phase in pregnancy.","PeriodicalId":93101,"journal":{"name":"Global journal of medical research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47824579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-23DOI: 10.34257/gjmrevol23is2pg1
Evellyn Vitória Sousa de Loureiro, Osvaldo Correia Damasceno, Ciro Francisco Moura de Assis Neto
Syphilis is considered a serious public health problem in Brazil and worldwide. The disease is especially worrying during pregnancy, as the mother can transmit the infection to her fetus, causing congenital syphilis. In this context, few articles have established a causal relationship between the growth in the number of cases of gestational and congenital syphilis in the Xingu Region and the construction of the Belo Monte Hydroelectric Plant. Objective: This study aims to analyze the influence of the intense migratory flow resulting from the construction of the Belo Monte Hydroelectric Power Plant on the cases of congenital syphilis. Methodology: This is an ecological study of congenital syphilis reported in the Xingu Region from January 2007 to 2019, using data obtained from the Information System of Notification Grievances. Results: It was found that there was an influence of the construction of the Belo Monte hydroelectric plant on the number of cases of congenital syphilis in the region.294 cases of congenital syphilis were reported. The most affected pregnant women were between 16 and 20 years old, were brown, had incomplete primary education and lived in the urban area. The study revealed numerous shortcomings in prenatal care provided in the Xingu Region.
{"title":"Possible Impact of the Construction of the Belo Monte Hydroelectric Power Plant on Cases of Congenital Syphilis in the Xingu Region","authors":"Evellyn Vitória Sousa de Loureiro, Osvaldo Correia Damasceno, Ciro Francisco Moura de Assis Neto","doi":"10.34257/gjmrevol23is2pg1","DOIUrl":"https://doi.org/10.34257/gjmrevol23is2pg1","url":null,"abstract":"Syphilis is considered a serious public health problem in Brazil and worldwide. The disease is especially worrying during pregnancy, as the mother can transmit the infection to her fetus, causing congenital syphilis. In this context, few articles have established a causal relationship between the growth in the number of cases of gestational and congenital syphilis in the Xingu Region and the construction of the Belo Monte Hydroelectric Plant. \u0000Objective: This study aims to analyze the influence of the intense migratory flow resulting from the construction of the Belo Monte Hydroelectric Power Plant on the cases of congenital syphilis. \u0000Methodology: This is an ecological study of congenital syphilis reported in the Xingu Region from January 2007 to 2019, using data obtained from the Information System of Notification Grievances.\u0000Results: It was found that there was an influence of the construction of the Belo Monte hydroelectric plant on the number of cases of congenital syphilis in the region.294 cases of congenital syphilis were reported. The most affected pregnant women were between 16 and 20 years old, were brown, had incomplete primary education and lived in the urban area. The study revealed numerous shortcomings in prenatal care provided in the Xingu Region.","PeriodicalId":93101,"journal":{"name":"Global journal of medical research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46587997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-23DOI: 10.34257/gjmrevol23is2pg15
Lin da Li, MD, FACOG, Sonia Hafiz, BA, Christy Stetter, BS, Kristin Riley, MD, FACOG
Objective: To further the understanding of long-term outcomes of endometriosis patients requiring colonic segmental resection (CSR) or low anterior resection (LAR). To improve counseling of patients with bowel endometriosis. Methods: Retrospective chart review at a single academic institution between 2000-2018 with 3-year follow-up of patients with CSR/LAR for endometriosis. 21 patients aged 18-45 at single academic institution between 1/1/2000 and 12/31/2018 with ICD9&10 codes of endometriosis AND CSR/LAR were included; 9 met criteria for endometriosis as indication for CSR/LAR were reviewed. Results: Pre- and post-operative symptoms were categorized into GI (hematochezia, dyschezia, tenesmus, incontinence, incomplete evacuation of bowel, and pre-operative colonoscopy), GYN (dysmenorrhea, dyspareunia, pelvic pain, and infertility), and GU (dysuria, frequency, urgency, incontinence, and incomplete emptying).
{"title":"Retrospective Review of Outcomes in Patients with Endometriosis and Colonic Segmental Resection (CSR) or Low Anterior Resection (LAR)","authors":"Lin da Li, MD, FACOG, Sonia Hafiz, BA, Christy Stetter, BS, Kristin Riley, MD, FACOG","doi":"10.34257/gjmrevol23is2pg15","DOIUrl":"https://doi.org/10.34257/gjmrevol23is2pg15","url":null,"abstract":"Objective: To further the understanding of long-term outcomes of endometriosis patients requiring colonic segmental resection (CSR) or low anterior resection (LAR). To improve counseling of patients with bowel endometriosis.\u0000Methods: Retrospective chart review at a single academic institution between 2000-2018 with 3-year follow-up of patients with CSR/LAR for endometriosis.\u000021 patients aged 18-45 at single academic institution between 1/1/2000 and 12/31/2018 with ICD9&10 codes of endometriosis AND CSR/LAR were included; 9 met criteria for endometriosis as indication for CSR/LAR were reviewed.\u0000Results: Pre- and post-operative symptoms were categorized into GI (hematochezia, dyschezia, tenesmus, incontinence, incomplete evacuation of bowel, and pre-operative colonoscopy), GYN (dysmenorrhea, dyspareunia, pelvic pain, and infertility), and GU (dysuria, frequency, urgency, incontinence, and incomplete emptying).","PeriodicalId":93101,"journal":{"name":"Global journal of medical research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47737356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-22DOI: 10.34257/gjreavol23is3pg1
Rishaad Abdoola, Yunfei Fang, Shengzhi Du, Paul Bartels, Christiaan Oosthuizen
Animal detection in aerial videos is a challenging problem due to the complex nature of the scenes involved as well as the natural ability of the animals to camouflage their environment. To assist with the detection and classification of animals for the purpose of nature conservation management, texture analysis is applied to aerial videos of wildlife scenes to segment the environment from the animals. To perform automatic wildlife surveying and animal monitoring, it is proposed to use GLCM texture segmentation to reduce the search area for animals in the aerial videos. Using the texture in the scene, the issues of a moving background and unpredictable state of the animal are avoided. The method presented is well suited to implementation on a UAV as it is easily parallelizable.
{"title":"Texture based Animal Segmentation in Aerial Videos","authors":"Rishaad Abdoola, Yunfei Fang, Shengzhi Du, Paul Bartels, Christiaan Oosthuizen","doi":"10.34257/gjreavol23is3pg1","DOIUrl":"https://doi.org/10.34257/gjreavol23is3pg1","url":null,"abstract":"Animal detection in aerial videos is a challenging problem due to the complex nature of the scenes involved as well as the natural ability of the animals to camouflage their environment. To assist with the detection and classification of animals for the purpose of nature conservation management, texture analysis is applied to aerial videos of wildlife scenes to segment the environment from the animals. To perform automatic wildlife surveying and animal monitoring, it is proposed to use GLCM texture segmentation to reduce the search area for animals in the aerial videos. Using the texture in the scene, the issues of a moving background and unpredictable state of the animal are avoided. The method presented is well suited to implementation on a UAV as it is easily parallelizable.","PeriodicalId":93101,"journal":{"name":"Global journal of medical research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43120856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Burkholderia pseudomallei is the agent of melioidosis. It is a bacterium from the hydrotelluric environment, highly pathogenic for humans. The geographical distribution of this disease is spreading and now affects the southwest of the Indian Ocean and in Mayotte Case presentation: We report four new cases of melioidosis with a case that was complicated by a failure of several organs (case 2) which were observed on Mayotte Island. The last two affected cases came from Madagascar. Burkholderia pseudomallei was isolated from blood cultures, confirming the diagnosis. Prolonged treatment with ceftazidime or Ertapenem intravenously followed by cotrimoxazole alone or combined with oral doxycycline led to complete recovery. Conclusion: Melioidosis poses a potential threat in the Indian Ocean region in general and Mayotte and should be carefully monitored. The high incidences of diabetes and climatologic conditions such as rainy seasons with the occurrence of tropical cyclones make Mayotte a possible setting for melioidosis. It would therefore not be surprising to see a marked increase in the incidence rate of melioidosis in the years to come.
{"title":"Melioidosis an Emerging Disease in the Indian Ocean Region: Case Series Study in Mayotte","authors":"Abdoulahy Diallo, Yacouba Dembélé, Amadou Cheick Tidiane Cisse, Issifou Yaya","doi":"10.34257/gjmrcvol23is3pg1","DOIUrl":"https://doi.org/10.34257/gjmrcvol23is3pg1","url":null,"abstract":"Background: Burkholderia pseudomallei is the agent of melioidosis. It is a bacterium from the hydrotelluric environment, highly pathogenic for humans. The geographical distribution of this disease is spreading and now affects the southwest of the Indian Ocean and in Mayotte \u0000Case presentation: We report four new cases of melioidosis with a case that was complicated by a failure of several organs (case 2) which were observed on Mayotte Island. The last two affected cases came from Madagascar. Burkholderia pseudomallei was isolated from blood cultures, confirming the diagnosis. Prolonged treatment with ceftazidime or Ertapenem intravenously followed by cotrimoxazole alone or combined with oral doxycycline led to complete recovery. \u0000Conclusion: Melioidosis poses a potential threat in the Indian Ocean region in general and Mayotte and should be carefully monitored. The high incidences of diabetes and climatologic conditions such as rainy seasons with the occurrence of tropical cyclones make Mayotte a possible setting for melioidosis. It would therefore not be surprising to see a marked increase in the incidence rate of melioidosis in the years to come.","PeriodicalId":93101,"journal":{"name":"Global journal of medical research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45049917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-21DOI: 10.34257/gjmrcvol23is3pg13
Rohan S. Kulkarni, Salva G Ahmed, Sunil S Kulkarni, V. Bhojwani
This bibliographic review evaluates Artificial Intelligence (AI) theory’s applications in the field of Family Medicine. Globally billions of people suffer from multiple health related issues throughout their lives including diseases of the heart, lungs, kidney, diabetes, and many forms of cancer. Diagnosis, remedy, and prevention of these disorders are multifaceted, and machine/computer based investigative tools for doctors are immediately needed to augment their decision-making. This study includes various applications of AI/machine learning (AI/ML) procedures in family medicine and its various sub-specialties. AI/ML-centered medicine offers better solutions over standard family medicine covering birth through end of life care. These include treatments for adolescents, geriatrics, disorders of pain and sleep, and sports injuries. However, several implementation hurdles for AI in clinical family medicine persist.
{"title":"Artificial Intelligence (AI) in Family Medicine– A Summary","authors":"Rohan S. Kulkarni, Salva G Ahmed, Sunil S Kulkarni, V. Bhojwani","doi":"10.34257/gjmrcvol23is3pg13","DOIUrl":"https://doi.org/10.34257/gjmrcvol23is3pg13","url":null,"abstract":"This bibliographic review evaluates Artificial Intelligence (AI) theory’s applications in the field of Family Medicine. Globally billions of people suffer from multiple health related issues throughout their lives including diseases of the heart, lungs, kidney, diabetes, and many forms of cancer. Diagnosis, remedy, and prevention of these disorders are multifaceted, and machine/computer based investigative tools for doctors are immediately needed to augment their decision-making. This study includes various applications of AI/machine learning (AI/ML) procedures in family medicine and its various sub-specialties. AI/ML-centered medicine offers better solutions over standard family medicine covering birth through end of life care. These include treatments for adolescents, geriatrics, disorders of pain and sleep, and sports injuries. However, several implementation hurdles for AI in clinical family medicine persist.","PeriodicalId":93101,"journal":{"name":"Global journal of medical research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47230799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-18DOI: 10.34257/gjmrbvol23is2pg29
Matheus Amorim Grigorio, Rayssa Blenda Martins, Lucca Piacesi Muniz De Melo, Victoria Carneiro Maciel, Dayane Carolini Rodrigues, Edson Brunetti Da Silva, Caio Almeida Andrade, Lorena de Sousa Moura, Juliane Alves de Mesquita, Mariana Santos Pinto, E. Oliveira, Isabella Furlan de Assis, Lucas Roberto Araújo Paiva Calabrich
Introduction: The uncontrolled use of antidepressant drugs can be potentially harmful to individual and collective health. Analgesics are often used inappropriately and carelessly, which can result in a number of negative effects like bacterial resistance, hypersensitivity, dependence, digestive bleeding, withdrawal symptoms, and even an increased risk for certain neoplasms (Ribeiro et al., 2010).The central nervous system, as well as the respiratory and digestive systems, are the sources of the complaints that are most frequently linked to self-medication, including headache, musculoskeletal pain, fever, respiratory infections, heartburn, abdominal pain, constipation, and diarrhea (Furtadoetal., 2019).
{"title":"Relationship between Antidepressant use a nd Increased Bacterial Resistance","authors":"Matheus Amorim Grigorio, Rayssa Blenda Martins, Lucca Piacesi Muniz De Melo, Victoria Carneiro Maciel, Dayane Carolini Rodrigues, Edson Brunetti Da Silva, Caio Almeida Andrade, Lorena de Sousa Moura, Juliane Alves de Mesquita, Mariana Santos Pinto, E. Oliveira, Isabella Furlan de Assis, Lucas Roberto Araújo Paiva Calabrich","doi":"10.34257/gjmrbvol23is2pg29","DOIUrl":"https://doi.org/10.34257/gjmrbvol23is2pg29","url":null,"abstract":"Introduction: The uncontrolled use of antidepressant drugs can be potentially harmful to individual and collective health. Analgesics are often used inappropriately and carelessly, which can result in a number of negative effects like bacterial resistance, hypersensitivity, dependence, digestive bleeding, withdrawal symptoms, and even an increased risk for certain neoplasms (Ribeiro et al., 2010).The central nervous system, as well as the respiratory and digestive systems, are the sources of the complaints that are most frequently linked to self-medication, including headache, musculoskeletal pain, fever, respiratory infections, heartburn, abdominal pain, constipation, and diarrhea (Furtadoetal., 2019).","PeriodicalId":93101,"journal":{"name":"Global journal of medical research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42368728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-18DOI: 10.34257/gjmrbvol23is2pg1
B. R. Ribeiro, Pedro Guimarães Machado, Grazielly Ribeiro Viana, Msc. Fellipe de Oliveira Cabral, Arize Duarte Vieira, Msc. Talita Barbosa Gomes, Msc. Matheus Del Penho, Msc. Higor Francesch Mota, Dr. Luciano de Carvalho Rapagña, Dr. Gilson Viana da Silva, Dra. Louisy Sanches dos Santos, Dra. Ana Luiza de Mattos Guaraldi, Dr. Cassius de Souza
Corynebacterium striatum is an emerging Gram-positive bacillus that presents tropism for the human microbiota, however, it has a high probability of presenting a multidrug-resistant (MDR) profile. In addition, several studies indicate its ability to cause serious infections in patients with varying levels of immune compromise. C.striatum samples may present different virulence mechanisms such as; disinfectant tolerance, motility, and bacterial biofilm formation. This work aims to evaluate the antimicrobial activity of the hydroalcoholic extract of Psidium guajava L. on MDR and MDS strains of C. striatum an alternative for treatment. We used the agar disk diffusion method to evaluate the susceptibility of bacterial samples under conditions of treatment with Psidium guajava L. The results showed in the disk diffusion test bacterial strains independent of their resistance profile MDS 1987 and MDR 1961 showed sensitivity to 100% crude extract of Psidium guajava L. showing inhibition halos of 13mm and 14mm, respectively. In the synergism test, a better result was obtained with the MDR1961 strain, and there was no result with the MDS1987 strain. The results of this course’s conclusion research can be considered a promising source for the search for new options against bacterial multidrug resistance, giving an incentive to seek new alternatives and isolation of molecules from plants to be able to use and fight multidrug-resistant infections.
{"title":"Detection of the Inhibitory Potential of Psidium Guajava L. Extract in Multidrug-Resistant Corynebacterium Striatum Strains Isolated from Nosocomial Outbreaks","authors":"B. R. Ribeiro, Pedro Guimarães Machado, Grazielly Ribeiro Viana, Msc. Fellipe de Oliveira Cabral, Arize Duarte Vieira, Msc. Talita Barbosa Gomes, Msc. Matheus Del Penho, Msc. Higor Francesch Mota, Dr. Luciano de Carvalho Rapagña, Dr. Gilson Viana da Silva, Dra. Louisy Sanches dos Santos, Dra. Ana Luiza de Mattos Guaraldi, Dr. Cassius de Souza","doi":"10.34257/gjmrbvol23is2pg1","DOIUrl":"https://doi.org/10.34257/gjmrbvol23is2pg1","url":null,"abstract":"Corynebacterium striatum is an emerging Gram-positive bacillus that presents tropism for the human microbiota, however, it has a high probability of presenting a multidrug-resistant (MDR) profile. In addition, several studies indicate its ability to cause serious infections in patients with varying levels of immune compromise. C.striatum samples may present different virulence mechanisms such as; disinfectant tolerance, motility, and bacterial biofilm formation. This work aims to evaluate the antimicrobial activity of the hydroalcoholic extract of Psidium guajava L. on MDR and MDS strains of C. striatum an alternative for treatment. We used the agar disk diffusion method to evaluate the susceptibility of bacterial samples under conditions of treatment with Psidium guajava L. The results showed in the disk diffusion test bacterial strains independent of their resistance profile MDS 1987 and MDR 1961 showed sensitivity to 100% crude extract of Psidium guajava L. showing inhibition halos of 13mm and 14mm, respectively. In the synergism test, a better result was obtained with the MDR1961 strain, and there was no result with the MDS1987 strain. The results of this course’s conclusion research can be considered a promising source for the search for new options against bacterial multidrug resistance, giving an incentive to seek new alternatives and isolation of molecules from plants to be able to use and fight multidrug-resistant infections.","PeriodicalId":93101,"journal":{"name":"Global journal of medical research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47837858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-18DOI: 10.34257/gjmrbvol23is2pg15
Matheus Amorim Grigorio, Esther Soneghet Baiocco e Silva, Vitória Patrícia Rodrigues Cunha, Layanne Bosse, Roberta Wassita Curi Schumann Rosso, Ana Beatriz Sales Vieira, Maria Jeane Veras Resende, Julia Pessoa de Melo Seixa, Lucas Belém Pessôa de Melo Guerra Seixas, Clarice de Abreu Pereira, G. M. Manca, Carolina Santoro Bueno, Paula Teixeira Silva, Marina Costa Florio, Juliane Alves de Mesquit, Raphael Vinicius Mendes Abreu, Édimo Júnior Queiroz Oliveira, Mariana Isabella de Medina Satriano, Andressa Akiko Koshikum, Dra. Aline de Amorim Duarte
Introduction: When analyzing the main depressive conditions and their treatments, we understand that it is not so simple to take care of psychosomatic conditions, because it is a pathology that has a significant epidemiological aspect and needs a good approach, therefore, psychedelic drugs come in as a an important alternative as a treatment. Methodology: This is a literature review with research in databases, using 60 scientific articles as a basis and being filtered based on scientific impact and approach. Results: Psychedelic agents are chemical substances that, in non-toxic doses, produce changes in conception and thinking in a state of mind, thus altering perception and reason. There are several substances with psychedelic actions, many of which are banned and considered illegal in several countries around the world, however there are regulators that regulate various drugs and substances, and many of these deserve attention, due to the great evolution in the scientific technical environment. Final considerations: It is important to understand the mechanism and how to analyze depressive conditions, as well as adjust changes in life, practices and quality of life.
{"title":"Psychedelic Drugs used in the Treatment of Depression: A Literature Review","authors":"Matheus Amorim Grigorio, Esther Soneghet Baiocco e Silva, Vitória Patrícia Rodrigues Cunha, Layanne Bosse, Roberta Wassita Curi Schumann Rosso, Ana Beatriz Sales Vieira, Maria Jeane Veras Resende, Julia Pessoa de Melo Seixa, Lucas Belém Pessôa de Melo Guerra Seixas, Clarice de Abreu Pereira, G. M. Manca, Carolina Santoro Bueno, Paula Teixeira Silva, Marina Costa Florio, Juliane Alves de Mesquit, Raphael Vinicius Mendes Abreu, Édimo Júnior Queiroz Oliveira, Mariana Isabella de Medina Satriano, Andressa Akiko Koshikum, Dra. Aline de Amorim Duarte","doi":"10.34257/gjmrbvol23is2pg15","DOIUrl":"https://doi.org/10.34257/gjmrbvol23is2pg15","url":null,"abstract":"Introduction: When analyzing the main depressive conditions and their treatments, we understand that it is not so simple to take care of psychosomatic conditions, because it is a pathology that has a significant epidemiological aspect and needs a good approach, therefore, psychedelic drugs come in as a an important alternative as a treatment. \u0000Methodology: This is a literature review with research in databases, using 60 scientific articles as a basis and being filtered based on scientific impact and approach.\u0000Results: Psychedelic agents are chemical substances that, in non-toxic doses, produce changes in conception and thinking in a state of mind, thus altering perception and reason. There are several substances with psychedelic actions, many of which are banned and considered illegal in several countries around the world, however there are regulators that regulate various drugs and substances, and many of these deserve attention, due to the great evolution in the scientific technical environment.\u0000Final considerations: It is important to understand the mechanism and how to analyze depressive conditions, as well as adjust changes in life, practices and quality of life.","PeriodicalId":93101,"journal":{"name":"Global journal of medical research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49283767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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