Pub Date : 2023-10-05DOI: 10.34257/gjmrkvol23is6pg29
Profa Dra Mara Villas Boas De Carvalho
Acomunicação é um espaço em que envolve a compaixão, a empatia, a solidariedade e interação diante de um paciente que se encontra à deriva entre o nascer, o viver e o processo de finitude. Todo Ser Existencial, se questiona e quer entender, como é esse processo existencial, um corpo, uma matéria viva, e que de um momento para outro, tornar-se-á pó,onde, o corpo é processado pelo tempo, ou seja, um tempo que tem um fim, um tempo imprevisível. Minhas inquietações diante da ação da arte do curar e cuidar, em face do processo de morrer, surgiram durante o curso de graduação, quando iniciei as atividades em campo de estágio. Já nessa época eu considerava deficiente a abordagem relacionada ao tema da comunicação “a morte e o morrer” pela perspectiva teórico-prática.
{"title":"Rethinking a Trajectory in the World of Healing and Care: Be Born, Live and Die","authors":"Profa Dra Mara Villas Boas De Carvalho","doi":"10.34257/gjmrkvol23is6pg29","DOIUrl":"https://doi.org/10.34257/gjmrkvol23is6pg29","url":null,"abstract":"Acomunicação é um espaço em que envolve a compaixão, a empatia, a solidariedade e interação diante de um paciente que se encontra à deriva entre o nascer, o viver e o processo de finitude. Todo Ser Existencial, se questiona e quer entender, como é esse processo existencial, um corpo, uma matéria viva, e que de um momento para outro, tornar-se-á pó,onde, o corpo é processado pelo tempo, ou seja, um tempo que tem um fim, um tempo imprevisível. Minhas inquietações diante da ação da arte do curar e cuidar, em face do processo de morrer, surgiram durante o curso de graduação, quando iniciei as atividades em campo de estágio. Já nessa época eu considerava deficiente a abordagem relacionada ao tema da comunicação “a morte e o morrer” pela perspectiva teórico-prática.","PeriodicalId":93101,"journal":{"name":"Global journal of medical research","volume":"85 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135546982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-05DOI: 10.34257/gjmrkvol23is6pg35
Mirela Moreno Almeida de Andrade, Rita De Cassia Tibério Araújo
OTranstorno do Espectro Autista (TEA) tem sido estudado e descrito há muitos anos, por vários pesquisadores, ao redor do mundo. Suas descrições e terminologias sofreram modificações importantes até chegarem à descrição mais atualizada, que foi publicada pelo Manual Diagnóstico e Estatístico dos Transtornos Mentais DSM-5 e, portanto, será o principal referencial teórico adotado neste estudo (AMERICAN PSYCHIATRIC ASSOCIATION, 2014). O Manual Diagnóstico e Estatístico dos Transtornos Mentais (DSM-5) define o Transtorno do Espectro Autista (TEA) como um transtorno do neurodesenvolvimento, caracterizado por déficits na comunicação e na interação social e pela presença de comportamentos, atividades ou interesses restritos e repetitivos (AMERICAN PSYCHIATRIC ASSOCIATION, 2014).
{"title":"Analysis of the Sensory Processing Profile of Students with Autistic Spectrum Disorder and its Influence on School Participation","authors":"Mirela Moreno Almeida de Andrade, Rita De Cassia Tibério Araújo","doi":"10.34257/gjmrkvol23is6pg35","DOIUrl":"https://doi.org/10.34257/gjmrkvol23is6pg35","url":null,"abstract":"OTranstorno do Espectro Autista (TEA) tem sido estudado e descrito há muitos anos, por vários pesquisadores, ao redor do mundo. Suas descrições e terminologias sofreram modificações importantes até chegarem à descrição mais atualizada, que foi publicada pelo Manual Diagnóstico e Estatístico dos Transtornos Mentais DSM-5 e, portanto, será o principal referencial teórico adotado neste estudo (AMERICAN PSYCHIATRIC ASSOCIATION, 2014). O Manual Diagnóstico e Estatístico dos Transtornos Mentais (DSM-5) define o Transtorno do Espectro Autista (TEA) como um transtorno do neurodesenvolvimento, caracterizado por déficits na comunicação e na interação social e pela presença de comportamentos, atividades ou interesses restritos e repetitivos (AMERICAN PSYCHIATRIC ASSOCIATION, 2014).","PeriodicalId":93101,"journal":{"name":"Global journal of medical research","volume":"80 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135546984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-05DOI: 10.34257/gjmrkvol23is6pg1
Amanda Dagnon da Silva, Marília Dagnon da Silva, Camila Tiemi Wassano, Rafaela Freitas Gonzalez, Elisângela Aparecida da Silva Lizzi, Roberta Cristina Barboza Galdêncio, Sidney Marcel Domingues
Objective: Our intention was to analyze production on the anti-vaccine movement and its implications for vaccination of the Brazilian population in the indexed scientific literature. Methods: We used the systematic scoping review to search the following databases: PubMed, Scopus, Web of Science, Burry, Lilacs/BVS and Scielo.JBI and PRISMA-SCR international protocols were adopted for the search and screening of scope-related articles. The guiding question was built through the acronym PCC (population, concept and context). The information was extracted, categorized regarding the relationship with the theme of the anti -vaccine movement and the implications for vaccination coverage of the Brazilian and/or general population.
目的:我们的目的是分析在索引的科学文献中反疫苗运动及其对巴西人口接种疫苗的影响。方法:采用系统范围评价方法检索PubMed、Scopus、Web of Science、Burry、Lilacs/BVS和Scielo数据库。采用JBI和PRISMA-SCR国际协议来检索和筛选与范围相关的文章。指导性问题是通过首字母缩略词PCC(人口、概念和背景)构建的。对这些资料进行了摘录和分类，以确定其与反疫苗运动主题的关系以及对巴西和(或)一般人口的疫苗接种覆盖率的影响。
{"title":"Anti-Vaccine Movement and its Implications for Vaccination Coverage of the Brazilian Population: A Scoping Review","authors":"Amanda Dagnon da Silva, Marília Dagnon da Silva, Camila Tiemi Wassano, Rafaela Freitas Gonzalez, Elisângela Aparecida da Silva Lizzi, Roberta Cristina Barboza Galdêncio, Sidney Marcel Domingues","doi":"10.34257/gjmrkvol23is6pg1","DOIUrl":"https://doi.org/10.34257/gjmrkvol23is6pg1","url":null,"abstract":"Objective: Our intention was to analyze production on the anti-vaccine movement and its implications for vaccination of the Brazilian population in the indexed scientific literature. Methods: We used the systematic scoping review to search the following databases: PubMed, Scopus, Web of Science, Burry, Lilacs/BVS and Scielo.JBI and PRISMA-SCR international protocols were adopted for the search and screening of scope-related articles. The guiding question was built through the acronym PCC (population, concept and context). The information was extracted, categorized regarding the relationship with the theme of the anti -vaccine movement and the implications for vaccination coverage of the Brazilian and/or general population.","PeriodicalId":93101,"journal":{"name":"Global journal of medical research","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135546420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-05DOI: 10.34257/gjmrkvol23is6pg49
Luiz José da Rocha Neto, Mariana Isabel Alvim Costa, Isabella de Caux Saez Bragança Barros, Fernanda Ribeiro Gonçalves Bolina Batista, Gabriel Plazzi Mandacaru
The development of a child encompasses the definition, measurement, and assessment of the expected normal patterns at each growth stage corresponding to their age. The child's passivity in response to stimuli has wide-ranging effects on a variety of domains, including communication skills and, consequently, cognitive, motor, and social development. Additionally, excessive screen time has a negative impact on the sleep-wake cycle, which in turn affects learning capacity and attention, as well as the risk of heart disease and depression. The lack of outdoor activities is closely linked to the growing trend of remote learning, which has resulted in an increased substitution of these activities with online games and video apps. Additionally, the use of electronic devices for more than three hours daily is associated with the worsening of symptoms related to ADHD, anxiety, and parental stress. However, following the COVID-19p and emic and the wide spread adoption of remote learning, screen time has significantly increased, making parental control more challenging, while the absence of physical activities has been exacerbated during this period, potentially leading to future consequences.
{"title":"Prolonged use of Screens in Children and their Harm","authors":"Luiz José da Rocha Neto, Mariana Isabel Alvim Costa, Isabella de Caux Saez Bragança Barros, Fernanda Ribeiro Gonçalves Bolina Batista, Gabriel Plazzi Mandacaru","doi":"10.34257/gjmrkvol23is6pg49","DOIUrl":"https://doi.org/10.34257/gjmrkvol23is6pg49","url":null,"abstract":"The development of a child encompasses the definition, measurement, and assessment of the expected normal patterns at each growth stage corresponding to their age. The child's passivity in response to stimuli has wide-ranging effects on a variety of domains, including communication skills and, consequently, cognitive, motor, and social development. Additionally, excessive screen time has a negative impact on the sleep-wake cycle, which in turn affects learning capacity and attention, as well as the risk of heart disease and depression. The lack of outdoor activities is closely linked to the growing trend of remote learning, which has resulted in an increased substitution of these activities with online games and video apps. Additionally, the use of electronic devices for more than three hours daily is associated with the worsening of symptoms related to ADHD, anxiety, and parental stress. However, following the COVID-19p and emic and the wide spread adoption of remote learning, screen time has significantly increased, making parental control more challenging, while the absence of physical activities has been exacerbated during this period, potentially leading to future consequences.","PeriodicalId":93101,"journal":{"name":"Global journal of medical research","volume":"81 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134947347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study explored the existing relationships between Advanced HIV Disease (AHD), Tuberculosis (TB), and Cryptococcal Antigen (CrAg) among People Living with HIV (PLHIV) in Nasarawa State, Nigeria. This was achieved by investigating the relationship and prevalence of TB and CrAg among individuals diagnosed with AHD in Nasarawa State; and by assessing the distribution and association of demographic characteristics of the study population with TB and Cryptococcal Antigen. This study employed a cross-sectional survey design, sampling respondents across different demographics at the same time. The study sample were individuals who are currently receiving antiretroviral treatment from our healthcare facilities in Nasarawa State, Nigeria. Results showed that TB and CrAg has low prevalence among the study population, however, compared to a larger population, this will be a serious concern. The study also suggest that the demographic information of the study population had no significant relationship on the development or presence of TB or CrAg, however, the study was ableto establish that PLHIVs who had AHD were mostly women (59.8%) in the State. Recommendation were made based on the study findings and the study concluded that the existing relationships among the study variables were not impacted significantly by either age or gender of the population.
本研究探讨了尼日利亚纳萨拉瓦州艾滋病毒感染者（PLHIV）中艾滋病晚期（AHD）、结核病（TB）和隐球菌抗原（CrAg）之间的现有关系。为此，研究人员调查了纳萨拉瓦州被诊断为艾滋病病毒感染者的人群中结核病和 CrAg 的关系和流行情况，并评估了研究人群的人口统计学特征与结核病和隐球菌抗原的分布和关联。本研究采用横断面调查设计，同时对不同人口统计学特征的受访者进行抽样调查。研究样本是目前正在尼日利亚纳萨拉瓦州医疗机构接受抗逆转录病毒治疗的个人。结果显示，结核病和 CrAg 在研究人群中的流行率较低，但与更大范围的人群相比，这将是一个严重问题。研究还表明，研究人群的人口统计学信息与肺结核或 CrAg 的发生或存在没有显著关系，但研究证实，该州患有 AHD 的艾滋病毒携带者大多为女性（59.8%）。根据研究结果提出了建议，研究得出结论认为，研究变量之间的现有关系并未受到人群年龄或性别的显著影响。
{"title":"Exploring the Interplay of AHD, TB, and Cryptococcal Antigen in Nasarawa State","authors":"Olufunmilola Abodunde, Folake Isona, Oluwasola Oni, Chinwe Umeozulu, Kayode Joseph, Faith Audu, Hafsat Usman, Adeniyi Ojuope, Temitope Olayemi, Esther Loyin","doi":"10.34257/ljmhrvol23is9pg1","DOIUrl":"https://doi.org/10.34257/ljmhrvol23is9pg1","url":null,"abstract":"This study explored the existing relationships between Advanced HIV Disease (AHD), Tuberculosis (TB), and Cryptococcal Antigen (CrAg) among People Living with HIV (PLHIV) in Nasarawa State, Nigeria. This was achieved by investigating the relationship and prevalence of TB and CrAg among individuals diagnosed with AHD in Nasarawa State; and by assessing the distribution and association of demographic characteristics of the study population with TB and Cryptococcal Antigen. This study employed a cross-sectional survey design, sampling respondents across different demographics at the same time. The study sample were individuals who are currently receiving antiretroviral treatment from our healthcare facilities in Nasarawa State, Nigeria. Results showed that TB and CrAg has low prevalence among the study population, however, compared to a larger population, this will be a serious concern. The study also suggest that the demographic information of the study population had no significant relationship on the development or presence of TB or CrAg, however, the study was ableto establish that PLHIVs who had AHD were mostly women (59.8%) in the State. Recommendation were made based on the study findings and the study concluded that the existing relationships among the study variables were not impacted significantly by either age or gender of the population.","PeriodicalId":93101,"journal":{"name":"Global journal of medical research","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139334910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-25DOI: 10.34257/gjmrfvol23is7pg35
Robson Natario Silveira Filho, Thomaz de Carvalho Lima Paiva, Breno Vasconcelos Lima Tenório França, Pedro Henrique Lins de Almeida, Savyo Firmino de Oliveira Costa, Gabriel Oliveira Ferro, Pedro Cavalcante Rocha, Annie Lis de Lima Ferreira, Maria Luiza Lima Cordeiro de Castro, Isadora Oliveira Barbosa, Laura Beatriz Tenorio Vitorino, Alice Cardoso Braga, Nycolle Beatriz Lima de Siqueira, Izadora Magalhães Vasconcellos, Matheus Pedrosa Cavalcante
Introduction: Tranexamic acid (TXA) is indicated for the control and prevention of hyperfibrinolysis-induced hemorrhages because it promotes increased clot stability. 11 Since its pre-hospital use is not yet well-defined, the purpose of this article is to evaluate the scientific research on its mechanism of action, indications, and contraindications to supplement the risk-benefit discussion. Methodology: The current study is a literature review, the database of which was taken from the SciELO (Scientific Electronic Library Online) and Pub Medplatforms.
{"title":"Use of Tranexamic Acid in Trauma in a Prehospital Context","authors":"Robson Natario Silveira Filho, Thomaz de Carvalho Lima Paiva, Breno Vasconcelos Lima Tenório França, Pedro Henrique Lins de Almeida, Savyo Firmino de Oliveira Costa, Gabriel Oliveira Ferro, Pedro Cavalcante Rocha, Annie Lis de Lima Ferreira, Maria Luiza Lima Cordeiro de Castro, Isadora Oliveira Barbosa, Laura Beatriz Tenorio Vitorino, Alice Cardoso Braga, Nycolle Beatriz Lima de Siqueira, Izadora Magalhães Vasconcellos, Matheus Pedrosa Cavalcante","doi":"10.34257/gjmrfvol23is7pg35","DOIUrl":"https://doi.org/10.34257/gjmrfvol23is7pg35","url":null,"abstract":"Introduction: Tranexamic acid (TXA) is indicated for the control and prevention of hyperfibrinolysis-induced hemorrhages because it promotes increased clot stability. 11 Since its pre-hospital use is not yet well-defined, the purpose of this article is to evaluate the scientific research on its mechanism of action, indications, and contraindications to supplement the risk-benefit discussion. Methodology: The current study is a literature review, the database of which was taken from the SciELO (Scientific Electronic Library Online) and Pub Medplatforms.","PeriodicalId":93101,"journal":{"name":"Global journal of medical research","volume":"128 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135816571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-25DOI: 10.34257/gjmrfvol23is7pg31
Argel Alves De Castro Filho, Gabriela Tatiana Vilela Ferreira Saran, Marcelo Anderson Nunes Santos, Bruna Neres Moreira da Fonseca, Lucca Cardoso Damasceno, Esther Mendonça dos Santos, Luciane Alves de Oliveira, Amanda Gomes Quiroga, Rávila Ruthiele Meireles Santos, Laianne Barros Martins de Alcântara, Davi Campos da Silva, Esther Calçado Lemos, Anelise Pilar Ferreira, Brianna Vitória Medeiros Bezerra Barros, Alycia Morais Borges Damasceno, Bruna Marçal Carvalho Mendes, Danilo Gomes Miranda, Dra. Aline de Amorim Duarte
This paper is based on a general analysis of pneumoconiosis and how it is related to work. Breathing in solid particles can cause the lung disease pneumoconiosis. The inhalation of solid particles is what causes it. Exposure to particles such as asbestos, silica, and coal dust is discussed as a central factor in the genesis of the disease, resulting in complex and specific inflammatory and repair processes for each etiologic agent. The methodological design was a comprehensive literature review between the years 2000 and 2023; the texts chosen were in the English language and searched in PubMed and SciELO databases. Coal dust in mining represents a risk, especially for workers in coal transportation and use, as well as for those involved in mineral excavation and mining. Silicosis, a disease linked to miners, resurfaces due to a lack of understanding of modern work practices.
{"title":"Work-Related Pneumoconiosis","authors":"Argel Alves De Castro Filho, Gabriela Tatiana Vilela Ferreira Saran, Marcelo Anderson Nunes Santos, Bruna Neres Moreira da Fonseca, Lucca Cardoso Damasceno, Esther Mendonça dos Santos, Luciane Alves de Oliveira, Amanda Gomes Quiroga, Rávila Ruthiele Meireles Santos, Laianne Barros Martins de Alcântara, Davi Campos da Silva, Esther Calçado Lemos, Anelise Pilar Ferreira, Brianna Vitória Medeiros Bezerra Barros, Alycia Morais Borges Damasceno, Bruna Marçal Carvalho Mendes, Danilo Gomes Miranda, Dra. Aline de Amorim Duarte","doi":"10.34257/gjmrfvol23is7pg31","DOIUrl":"https://doi.org/10.34257/gjmrfvol23is7pg31","url":null,"abstract":"This paper is based on a general analysis of pneumoconiosis and how it is related to work. Breathing in solid particles can cause the lung disease pneumoconiosis. The inhalation of solid particles is what causes it. Exposure to particles such as asbestos, silica, and coal dust is discussed as a central factor in the genesis of the disease, resulting in complex and specific inflammatory and repair processes for each etiologic agent. The methodological design was a comprehensive literature review between the years 2000 and 2023; the texts chosen were in the English language and searched in PubMed and SciELO databases. Coal dust in mining represents a risk, especially for workers in coal transportation and use, as well as for those involved in mineral excavation and mining. Silicosis, a disease linked to miners, resurfaces due to a lack of understanding of modern work practices.","PeriodicalId":93101,"journal":{"name":"Global journal of medical research","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135815727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-25DOI: 10.34257/gjmrfvol23is7pg19
Renata Melo de Carvalhoo Lima, Luciane alves de Oliveira, Marilia Albuquerque Barreto, Matheus Henrick Pereira de Almeida, Maria Jullia Alvares de Melo, Bruno Renan de Carvalho Lopes, Nahara Hajar Costa, Letícia Verônica Rizzato Graciano, Tábata de Oliveira Silva, Augusto Henrique de Brito Peres, Vinicius Rahal Basseto, Maria Eugênia Pissinati Gomes, Fernanda Kelly Araújo Lima, Giovanna de Carvalho Vilas Boas, Ana Carolina Lustosa Araújo Souza, Beatriz Regis da Cunha, Lina Borges Cavalcante, Dra. Aline de Amorim Duarte
This literature review focuses on the analysis of renal denervation therapy as a potential treatment for difficult-to-control hypertension. Systemic arterial hypertension (SAH) is a prevalent condition with various approaches to achieving control, including life style modifications, pharmacological interventions, and surgical treatments. The fluctuations in blood pressure within the kidneys occur due to the stimulation or inhibition of sensory and motor pathways in the renal nerves. Each of these modifications is linked to the underlying condition in the progression of hypertension. The employed methodology involves the ablation of renal afferent and efferent nerves using a catheter through percutaneous intervention facilitated by ultrasound.
{"title":"Renal Denervation for the Treatment of Hypertension","authors":"Renata Melo de Carvalhoo Lima, Luciane alves de Oliveira, Marilia Albuquerque Barreto, Matheus Henrick Pereira de Almeida, Maria Jullia Alvares de Melo, Bruno Renan de Carvalho Lopes, Nahara Hajar Costa, Letícia Verônica Rizzato Graciano, Tábata de Oliveira Silva, Augusto Henrique de Brito Peres, Vinicius Rahal Basseto, Maria Eugênia Pissinati Gomes, Fernanda Kelly Araújo Lima, Giovanna de Carvalho Vilas Boas, Ana Carolina Lustosa Araújo Souza, Beatriz Regis da Cunha, Lina Borges Cavalcante, Dra. Aline de Amorim Duarte","doi":"10.34257/gjmrfvol23is7pg19","DOIUrl":"https://doi.org/10.34257/gjmrfvol23is7pg19","url":null,"abstract":"This literature review focuses on the analysis of renal denervation therapy as a potential treatment for difficult-to-control hypertension. Systemic arterial hypertension (SAH) is a prevalent condition with various approaches to achieving control, including life style modifications, pharmacological interventions, and surgical treatments. The fluctuations in blood pressure within the kidneys occur due to the stimulation or inhibition of sensory and motor pathways in the renal nerves. Each of these modifications is linked to the underlying condition in the progression of hypertension. The employed methodology involves the ablation of renal afferent and efferent nerves using a catheter through percutaneous intervention facilitated by ultrasound.","PeriodicalId":93101,"journal":{"name":"Global journal of medical research","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135816476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-20DOI: 10.34257/gjmrbvol23is3pg15
Henrique Hollanda Larangeira, Luciane Alves de Oliveira, Renata Gomes Ramalho dos Santos, Cínthia Pereira Jacomini, Júlia Maria Polastri, Lucca Cardoso Damasceno, Nilcele Freire de Oliveira, Lucas Roberto Araújo Paiva Calabrich, Ana Karla Tenório Holanda, Esther Mendonça dos Santos, Gabriela Tomazini Rodrigues Pereira Amorim, Letícia de Ávila Carvalho, Tamires Santos Pinheiro, Matheus Delgado Lima Teixeira, Maria Luísa Gonçalves Vieira, Thamirys Sartori de Souza, Dra. Aline de Amorim Duarte
This review of the literature examines the use of antiepileptic medications and how they relate to gut microbiota. Relationships exist between the makeup of the intestinal microbiota and the development and execution of the most fundamental physiological processes. Additionally, it affects the functioning of the central nervous system (CNS) by interacting with the microbiota-intestine-brain axis. The use of pharmaceutical medication is one of the factors that can alter the composition of the gut microbiota. When treating epilepsy, various drug types are used, each with a different mechanism of action. Among the medications in question are to piramate, primidone, phenytoin, carbamazepine, and phenobarbital. The similarity in structure and function between enteric and nerve cells establishes the connection between the brain and the gut. Valproic acid significantly reduced intestinal inflammation in research involving rats with colitis. Its limited ability to treat seizures in these circumstances may be due to the enterocytes limited ability to absorb this medicine. The study came to the conclusion that colitis patients and people with healthy gut, brain, and microbiota interactions typically respond better to antiepileptics and anticonvulsants than people with imbalances in this axis. These imbalances can result in a lower seizure threshold and an increased frequency of epileptic seizures.
{"title":"Antiepileptic Drugs and the Relationship with the Intestinal Microbiota","authors":"Henrique Hollanda Larangeira, Luciane Alves de Oliveira, Renata Gomes Ramalho dos Santos, Cínthia Pereira Jacomini, Júlia Maria Polastri, Lucca Cardoso Damasceno, Nilcele Freire de Oliveira, Lucas Roberto Araújo Paiva Calabrich, Ana Karla Tenório Holanda, Esther Mendonça dos Santos, Gabriela Tomazini Rodrigues Pereira Amorim, Letícia de Ávila Carvalho, Tamires Santos Pinheiro, Matheus Delgado Lima Teixeira, Maria Luísa Gonçalves Vieira, Thamirys Sartori de Souza, Dra. Aline de Amorim Duarte","doi":"10.34257/gjmrbvol23is3pg15","DOIUrl":"https://doi.org/10.34257/gjmrbvol23is3pg15","url":null,"abstract":"This review of the literature examines the use of antiepileptic medications and how they relate to gut microbiota. Relationships exist between the makeup of the intestinal microbiota and the development and execution of the most fundamental physiological processes. Additionally, it affects the functioning of the central nervous system (CNS) by interacting with the microbiota-intestine-brain axis. The use of pharmaceutical medication is one of the factors that can alter the composition of the gut microbiota. When treating epilepsy, various drug types are used, each with a different mechanism of action. Among the medications in question are to piramate, primidone, phenytoin, carbamazepine, and phenobarbital. The similarity in structure and function between enteric and nerve cells establishes the connection between the brain and the gut. Valproic acid significantly reduced intestinal inflammation in research involving rats with colitis. Its limited ability to treat seizures in these circumstances may be due to the enterocytes limited ability to absorb this medicine. The study came to the conclusion that colitis patients and people with healthy gut, brain, and microbiota interactions typically respond better to antiepileptics and anticonvulsants than people with imbalances in this axis. These imbalances can result in a lower seizure threshold and an increased frequency of epileptic seizures.","PeriodicalId":93101,"journal":{"name":"Global journal of medical research","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136309224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-20DOI: 10.34257/gjmrbvol23is3pg1
Henrique Hollanda Larangeira, Tábata de Oliveira Silva, Rafaela da Silva Schottz, Ingrid Fabric Gouveia Lima, Lina Borges Cavalcante, Marcus Antonio Studart da Cunha Frota, Janaína Gomes da Rocha, Lucas Martins Ferreira Guimaraes, Henrique de Castro Veiga, Idacir França Bottoli, Júlia Lottermann Vinhas, José Maria Teixeira de Oliveira, Maria Eduarda Lima de Aquino, Aline Bezerra Vargas, Eduarda de Oliveira, Lucas Belém Pessôa de Melo Guerra Seixas, Julia Pessoa de Melo Seixas, Dra. Aline de Amorim Duarte
Introduction: Understanding that cancer is a pathology that is challenging to detect, treat, and comprehend is what makes the study of cancer so important. The goal of this case study is to show how a 20-year-old woman was affected by a variety of factors and symptoms that, when combined, raised suspicion of Ewing's sarcoma, the second most common primary tumor in children and young adults. Ewing's sarcoma has the characteristics of being an aggressive malignancy originating in the bones.
{"title":"Clinical and Epidemiological Profile of Patients with Ewing's Sarcoma","authors":"Henrique Hollanda Larangeira, Tábata de Oliveira Silva, Rafaela da Silva Schottz, Ingrid Fabric Gouveia Lima, Lina Borges Cavalcante, Marcus Antonio Studart da Cunha Frota, Janaína Gomes da Rocha, Lucas Martins Ferreira Guimaraes, Henrique de Castro Veiga, Idacir França Bottoli, Júlia Lottermann Vinhas, José Maria Teixeira de Oliveira, Maria Eduarda Lima de Aquino, Aline Bezerra Vargas, Eduarda de Oliveira, Lucas Belém Pessôa de Melo Guerra Seixas, Julia Pessoa de Melo Seixas, Dra. Aline de Amorim Duarte","doi":"10.34257/gjmrbvol23is3pg1","DOIUrl":"https://doi.org/10.34257/gjmrbvol23is3pg1","url":null,"abstract":"Introduction: Understanding that cancer is a pathology that is challenging to detect, treat, and comprehend is what makes the study of cancer so important. The goal of this case study is to show how a 20-year-old woman was affected by a variety of factors and symptoms that, when combined, raised suspicion of Ewing's sarcoma, the second most common primary tumor in children and young adults. Ewing's sarcoma has the characteristics of being an aggressive malignancy originating in the bones.","PeriodicalId":93101,"journal":{"name":"Global journal of medical research","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136309055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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