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Severe Hypernatremic Dehydration in a Neonate 新生儿严重高钠血症脱水
Pub Date : 2024-01-02 DOI: 10.34257/gjmrfvol23is10pg9
Aida Correia de Azevedo, A. S. Rodrigues, Beatriz Parreira de Andrade, Raquel Cardoso, Susana Lopes
Hypernatremia, a rare condition in newborns, is marked by elevated plasma sodium levels exceeding 150 mEq/L. It is more common in newborns who are exclusively breastfed or with excessive weight loss. Hypernatremic dehydration (HD) presents severe risks, including cerebral edema and other neurological complications.A female newborn, 12 days old (birth weight: 2800g), was brought to the Emergency Department due to a 30% decrease in birth weight and reduced urine output. The newborn was solely breastfed every 2 hours, with a good notion of adequate reflexes and tolerance. Physical examination revealed a skeletal appearance, jaundice, sunken eyes and skin turgor. Blood pressure measurement was unsuccessful, while capillary blood glucose was 96g/dL. A saline bolus (10 mL/Kg)was administered. Venous blood gas analysis showed pH 7.39, lactate 4.3 mmol/L, HCO3-21.8 mmol/L, and Na+ 180 mEq/L.
高钠血症是新生儿中的一种罕见病症,表现为血浆钠含量升高,超过 150 mEq/L。这种情况在纯母乳喂养或体重过度减轻的新生儿中更为常见。一名出生 12 天的女性新生儿(出生体重:2800 克)因出生体重下降 30%、尿量减少而被送到急诊科。该新生儿仅靠母乳喂养,每 2 小时一次,反射和耐受性良好。体格检查显示新生儿有骨骼、黄疸、眼窝凹陷和皮肤潮红。血压测量不成功,毛细血管血糖为 96g/dL。给他注射了生理盐水(10 毫升/千克)。静脉血气分析显示 pH 7.39,乳酸 4.3 mmol/L,HCO3-21.8 mmol/L,Na+ 180 mEq/L。
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引用次数: 0
Histological Grading of Breast Cancer Malignancy using Automated Image Analysis and Subsequent Machine Learning 利用自动图像分析和后续机器学习对乳腺癌恶性程度进行组织学分级
Pub Date : 2023-12-25 DOI: 10.34257/gjmrcvol23is3pg39
Paulo César Ribeiro Boasquevisque, R. Jarske, Célio Siman Mafra Nunes, Isabela Passos Pereira Quintaes, Samuel Santana Sodré, Dominik Lenz, PhD
Aim: The objective of this study was to determine the histological degree of breast cancer malignancy using the automated principle of machine learning with the free access computer programs Cell Profiler and Tanagra. Methods and results: Digital photographs of neoplastic tissue histological slides were obtained from 224 women with breast cancer. The digitized images were transferred to the Cell Profiler software and treated according to a predetermined algorithm, resulting in a database exported to the Tanagra software for further automated classification of the histological degree of malignancy. The Kappa index of agreement between the medical pathologist and the automated analysis performed in the Tanagra software was 0.91 for the tubular score, 0.55 for the nuclear score, and 0.49 for the mitotic index score.
目的:本研究的目的是通过免费使用的计算机程序 Cell Profiler 和 Tanagra,利用机器学习的自动化原理来确定乳腺癌恶性程度。方法和结果从 224 名患乳腺癌的妇女身上获取了肿瘤组织切片的数码照片。数字化图像被传输到Cell Profiler软件中,并根据预先确定的算法进行处理,最终形成一个数据库,并输出到Tanagra软件中,以进一步对组织学恶性程度进行自动分类。医学病理学家与 Tanagra 软件自动分析的 Kappa 一致指数分别为:管状评分 0.91,核状评分 0.55,有丝分裂指数评分 0.49。
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引用次数: 0
Frailty in the Elderly and its Impact on Quality of Life 老年人体弱及其对生活质量的影响
Pub Date : 2023-12-21 DOI: 10.34257/gjmrkvol23is7pg17
Ivete Maria Carneiro de Sousa Ricardi, Gabriele Pereira Martins Carneiro, Vitória Loureiro, Carolina Santoro Bueno, Rebecca von Dannecker Andrade, Luciane Alves de Oliveira, João de Oliveira Neto
Introduction:The elderly undergo bio psychosocial and functional changes that reduce their ability to adapt to the environment. In addition, pathological processes occur that make the elderly more susceptible to frailty.Methodology:The methodology used for this analysis was based on a literature review, in which the sources were obtained from the SciELO, Google Scholar, and PubMed data platforms.Discussion: Ageing raises concerns about the impact on the quality of life of these individuals (Lenardt et al., 2016). According to Who (1995), quality of life is an individual's perception of their position in life according to the context in which they live and their relationship with expectations, goals, and concerns. In this sense, it can be seen that quality of life suffers from internal and external influences (Jesus et al., 2018).
导言:老年人经历了生物社会心理和功能的变化,这降低了他们适应环境的能力。方法:本分析所使用的方法基于文献综述,文献来源来自 SciELO、Google Scholar 和 PubMed 数据平台:老龄化引发了对这些人生活质量影响的担忧(Lenardt 等人,2016 年)。根据 Who(1995 年)的观点,生活质量是个人根据其生活环境及其与期望、目标和关切的关系对其生活状况的感知。从这个意义上可以看出,生活质量受到内部和外部的影响(Jesus et al.)
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引用次数: 0
Long COVID Syndrome and i ts Impact 长 COVID 综合征及其影响
Pub Date : 2023-12-21 DOI: 10.34257/gjmrkvol23is7pg1
Esther Soneghet, Beatriz Vilela Palazzo, Raissa de Sousa Guerra, Renata Gomes Ramalho dos Santos, Julia Nicolau Barbieri, Eduarda Monteiro Machado, Gabriela Tomazini Rodrigues Pereira Amorim, Gabriela Salomão Espírito Santo Mendonça, Guilherme Silva Miranda, Pollyane Vieira de Almeida, Bruno Renan de Carvalho Lopes, Marina Lima Rodrigues, Mariana Isabella de Medina Satriano, João de Oliveira Neto
Introduction: When addressing the COVID-19 pandemic, one must also address its remnants, as well as the Long COVID-19 Syndrome,or just Long COVID-19, which addresses a group of symptoms common to COVID, but which persist even after the infectious picture has ended. The main symptoms are fatigue, dyspnea, joint and muscle pain,headaches, and brain fog. Other symptoms, such as arrhythmias, anxiety, and sleep disorders, have been described, but the cause of these sequelae and the reason for them are not known for certain. Methodology: This is a literaturere view based on the SciELO and PubMed data platforms. The search period was July 2023, meeting the inclusion criteria of articles from 2000 to 2023, in Portuguese and English, online, and in full text. The following health descriptors (DeCS) were used as strategies to better evaluate the texts: "Long COVID syndrome", "COVID" and "Post COVID syndrome".
导言:在应对 COVID-19 大流行时,我们还必须应对其残余症状以及长 COVID-19 综合征(或简称为长 COVID-19)。主要症状包括疲劳、呼吸困难、关节和肌肉疼痛、头痛和脑雾。其他症状,如心律失常、焦虑和睡眠障碍,也有描述,但这些后遗症的成因和原因尚不确定。研究方法:这是基于 SciELO 和 PubMed 数据平台的文献综述。检索期为 2023 年 7 月,符合纳入标准的文章为 2000 年至 2023 年的葡萄牙语和英语在线全文。为了更好地评估文本,使用了以下健康描述符(DeCS)作为策略:"长 COVID 综合征"、"COVID "和 "后 COVID 综合征"。
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引用次数: 0
Radiation Dose Tracking in Digital Mammography: Evaluation of Population Profiles through Automatic Data Extraction from the DICOM Header 数字乳腺 X 射线摄影中的辐射剂量跟踪:通过从 DICOM 标头自动提取数据评估人群概况
Pub Date : 2023-11-15 DOI: 10.34257/ljmhrvol23is11pg1
H. Schiabel, Eny Moreira Ruberti Filha, Oswaldo Jorge Neto, L. B. Verçosa
International regulatory organizations for quality control of X-ray systems, such as the International Atomic Energy Agency (IAEA), have implemented protocols for acceptance testing of digital mammography and breast tomosynthesis equipment, aiming to establish quality standards in radiology services. However, these guidelines are usually based on tests with breast phantoms with standardizedthicknesses and compositions, often not representative of the patient population profiles at those services. In a prior study, we developed a computational system designed to automatically tracking and managing data extracted from the image acquisition processes of digital mammography and breast tomosynthesis, stored on a DICOM SCP (Service Class Provider) server. This approach enables obtaining technical reports characterizing exposure parameters and tests have shown that the reference levels outlined in international standards for breast composition and radiation dose do not accurately reflect the characteristics of the actual patient population. Thus this study describes data collection and corresponding analysis for the dose tracking process primarily on three digital mammography systems of different radiological services. Extensive image datasets from these systems were obtained using a new application described previously, with a focus on dose profiles generated during exposures. Graphical representations resultingfrom the datasets are presented, along with analysis of skin entrance and mean glandular doses distributions, average kV and mAs applied during the exams together with the target/filter combinations, radiographic density distribution, as well as the age and breast thickness characteristic of the respective population submitted to exposures in each of those mammography services. Additionally, the extent of information and ease of acquisition provided by the tool for performance evaluation of digital mammography services is discussed
国际原子能机构(IAEA)等负责 X 射线系统质量控制的国际监管组织已经实施了数字乳腺 X 射线照相术和乳腺断层合成术设备验收测试协议,旨在建立放射服务的质量标准。然而,这些指南通常都是基于具有标准化厚度和成分的乳房模型进行测试,而这些模型通常并不能代表这些服务机构的病人群体特征。在之前的一项研究中,我们开发了一个计算系统,用于自动跟踪和管理从数字乳腺 X 射线照相术和乳腺断层合成术图像采集过程中提取的数据,这些数据存储在 DICOM SCP(服务类提供商)服务器上。测试表明,乳腺成分和辐射剂量国际标准中列出的参考水平并不能准确反映实际患者群体的特征。因此,本研究描述了主要针对不同放射服务机构的三台数字乳腺 X 射线摄影系统的剂量跟踪过程的数据收集和相应分析。这些系统的大量图像数据集是通过之前介绍过的一种新应用软件获取的,重点是曝光过程中产生的剂量曲线。数据集生成的图表展示了皮肤入口剂量和平均腺体剂量分布、检查期间使用的平均 kV 和 mAs 以及目标/滤波器组合、放射密度分布,以及每个乳腺 X 射线照相服务机构接受照射人群的年龄和乳房厚度特征。此外,还讨论了数字乳腺 X 射线照相服务性能评估工具所提供信息的范围和获取的难易程度。
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引用次数: 0
Optimizing Hyaluronic Acid: A Comprehensive Review of Rheological Insights for Clinical Practice 优化透明质酸:全面回顾流变学对临床实践的启示
Pub Date : 2023-11-08 DOI: 10.34257/gjmrfvol23is8pg1
Fernanda Lacerda de Almeida Romanó Peixoto, Isabela Espasandin, Paulo Henrique Bastos, Juliana do Carmo Públio, Antony de Paula Barbosa
The aging process of the face is characterized by transformations in the skin, bone, and adipose tissue. As the understanding of these changes has expanded, so too has the range of available filler products in the market. To maximize the effectiveness of hyaluronic acid, it is crucial to have a comprehensive understanding of its rheological properties. The numerous commercially available brands of hyaluronic acid differ in several aspects, such as the purity of their raw materials, methods of manufacturing, concentration of hyaluronic acid, presence and level of cross-linking, and ability to provide volume and withstand degradation. Aiming at the most assertive use of this product, features as viscosity (η), complex modulus (G*), elastic modulus (G"), tan d, cross-linking, concentration and swelling factor must be addressed, correlating them with their expected clinical effects.
面部衰老过程的特点是皮肤、骨骼和脂肪组织发生变化。随着人们对这些变化的认识不断加深,市场上可供选择的填充产品也越来越多。为了最大限度地发挥透明质酸的功效,全面了解其流变特性至关重要。市面上的透明质酸品牌众多,在原材料的纯度、制造方法、透明质酸的浓度、是否存在交联以及交联的程度、提供体积和耐降解的能力等多个方面都存在差异。为了最有效地使用这种产品,必须考虑粘度 (η)、复合模量 (G*)、弹性模量 (G")、tan d、交联、浓度和膨胀因子等特性,并将它们与预期的临床效果联系起来。
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引用次数: 0
Analysis of Influence and Composition of the Metal Alloys of Two Implant Drill System 金属合金对双种植体钻头系统的影响及成分分析
Pub Date : 2023-11-01 DOI: 10.34257/gjmrjvol23is3pg23
Lara Rabelo Aragão, Jiovanne Rabelo Neri, Pedro Henrique Gonçalves Holanda Amorim, Rafael Linard Avelar, Isabelle Ramos Pereira Lima, Roque Soares Martins, Alex Oliveira De Moura, Thiago Vasconcelos Melo
Purpose: The mechanical behavior of two different implant drill systems for osteotomy preparation using polyurethane foam models were evaluated. Methods: Fourteen polyurethane foam models and 28 Neodent® drills and 28 Dentoflex® drills were used. In a controlled environment, the perforations were timed, and an infrared digital thermometer and a K-type sensor were used to measure the temperature before and after perforations. Each group was divided into 7 subgroups: S5 = 5 perforations, S10 = 10 perforations, S15 = 15 perforations, S20 = 20 perforations, S30 = 30 perforations, S40 = 40 perforations, and S50 = 50 perforations. Results: In the S5 and S10 subgroup, drilling time of the drills with three helical cutting edges was longer (p <0.05) and temperature 1 was lower (p = 0.034) in the S10 group.
目的:利用聚氨酯泡沫模型评估两种不同种植体钻孔系统用于截骨准备的力学行为。方法:采用聚氨酯泡沫模型14个,Neodent®钻头28个,denttoflex®钻头28个。在受控环境下,对射孔进行定时,使用红外数字温度计和k型传感器测量射孔前后的温度。每组分为7个亚组:S5 = 5个孔,S10 = 10个孔,S15 = 15个孔,S20 = 20个孔,S30 = 30个孔,S40 = 40个孔,S50 = 50个孔。结果:在S5和S10亚组中,S10组三螺旋切削刃钻头的钻孔时间更长(p <0.05),温度1更低(p = 0.034)。
{"title":"Analysis of Influence and Composition of the Metal Alloys of Two Implant Drill System","authors":"Lara Rabelo Aragão, Jiovanne Rabelo Neri, Pedro Henrique Gonçalves Holanda Amorim, Rafael Linard Avelar, Isabelle Ramos Pereira Lima, Roque Soares Martins, Alex Oliveira De Moura, Thiago Vasconcelos Melo","doi":"10.34257/gjmrjvol23is3pg23","DOIUrl":"https://doi.org/10.34257/gjmrjvol23is3pg23","url":null,"abstract":"Purpose: The mechanical behavior of two different implant drill systems for osteotomy preparation using polyurethane foam models were evaluated. Methods: Fourteen polyurethane foam models and 28 Neodent® drills and 28 Dentoflex® drills were used. In a controlled environment, the perforations were timed, and an infrared digital thermometer and a K-type sensor were used to measure the temperature before and after perforations. Each group was divided into 7 subgroups: S5 = 5 perforations, S10 = 10 perforations, S15 = 15 perforations, S20 = 20 perforations, S30 = 30 perforations, S40 = 40 perforations, and S50 = 50 perforations. Results: In the S5 and S10 subgroup, drilling time of the drills with three helical cutting edges was longer (p <0.05) and temperature 1 was lower (p = 0.034) in the S10 group.","PeriodicalId":93101,"journal":{"name":"Global journal of medical research","volume":"13 6","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135455853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role of Classification of Endoscopic Sinus Surgery in Surgical Planning 内镜鼻窦手术分类在手术计划中的作用
Pub Date : 2023-11-01 DOI: 10.34257/gjmrjvol23is3pg15
Dr. Nanda Kishore G., Dr. Satish Chandra Tripuraneni, Dr. Sravanthi K. K., Dr. Sameera G
Endoscopic sinus surgery being an approach, there is no proper classification system to address the extent of surgery required for Sinonasal pathologies. The current study attempts to propose and evaluate the role and efficacy of a classification system for endoscopic sinus surgery in addressing various Sinonasal and skull base pathologies. Materials and methods: It's a prospective study that included 50 patients. We classified ESS into six types based on the extent of surgery. After thorough evaluation, depending on the extent of the disease, all 50 patients were planned and treated according to the classification. Patients were followed for one year.
内窥镜鼻窦手术作为一种方法,没有适当的分类系统来解决鼻窦病变所需的手术程度。本研究试图提出并评估一种内镜鼻窦手术分类系统在处理各种鼻窦和颅底病变中的作用和疗效。材料与方法:前瞻性研究,纳入50例患者。我们根据手术的程度将ESS分为六种类型。经过全面的评估,根据病情的严重程度,对所有50例患者进行分类计划和治疗。患者随访一年。
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引用次数: 0
Impact and Prevalence of Musculoskeletal Injuries due to Accident at Work in Brazil, 2015-2020 2015-2020年巴西工伤事故对肌肉骨骼损伤的影响和流行程度
Pub Date : 2023-10-21 DOI: 10.34257/gjmrhvol23is2pg1
Bianca G D Oliveira, Iago O Braga, Leonardo C Borduchi, Pedro A M O Siqueira, Renan C Peccinelli
Goal: Recognize the relevance of hospitalizations for musculoskeletal injuries due to accidents at work in Brazil. Methods: It is a retrospective epidemiological study, qualitative/quantitative with secondary data analysis and cross-sectional typology in the public databases of the Ministry of Labor and Social Security, delivered by the Federal Government. Descriptors in health sciences: musculoskeletal injuries; accident at work; injuries due to accidents at work; workers; absenteeism. Results: In Brazil, during 2015 to 2020, there is evidence of a high number of accidents at work resulting in 65.9% of musculoskeletal injuries. The most affected age was between 30-39 years, the male gender corresponded to 63.3% of the cases, upper limb injuries were the most prevalent, and 36.1 billion were spent in aids.
目标:认识到巴西因工作事故造成的肌肉骨骼损伤住院治疗的相关性。方法:采用回顾性流行病学研究方法,定性/定量结合二手资料分析和联邦政府劳动和社会保障部公共数据库的横断面类型学。健康科学中的描述词:肌肉骨骼损伤;工作事故;因工作事故造成的伤害;工人;旷工。结果:在巴西,有证据表明,在2015年至2020年期间,工作中的大量事故导致65.9%的肌肉骨骼损伤。发病年龄以30 ~ 39岁为主,男性占63.3%,以上肢损伤为主,总花费361亿元。
{"title":"Impact and Prevalence of Musculoskeletal Injuries due to Accident at Work in Brazil, 2015-2020","authors":"Bianca G D Oliveira, Iago O Braga, Leonardo C Borduchi, Pedro A M O Siqueira, Renan C Peccinelli","doi":"10.34257/gjmrhvol23is2pg1","DOIUrl":"https://doi.org/10.34257/gjmrhvol23is2pg1","url":null,"abstract":"Goal: Recognize the relevance of hospitalizations for musculoskeletal injuries due to accidents at work in Brazil. Methods: It is a retrospective epidemiological study, qualitative/quantitative with secondary data analysis and cross-sectional typology in the public databases of the Ministry of Labor and Social Security, delivered by the Federal Government. Descriptors in health sciences: musculoskeletal injuries; accident at work; injuries due to accidents at work; workers; absenteeism. Results: In Brazil, during 2015 to 2020, there is evidence of a high number of accidents at work resulting in 65.9% of musculoskeletal injuries. The most affected age was between 30-39 years, the male gender corresponded to 63.3% of the cases, upper limb injuries were the most prevalent, and 36.1 billion were spent in aids.","PeriodicalId":93101,"journal":{"name":"Global journal of medical research","volume":"161 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135514351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effectiveness of a Structured Training Program in Transforming to an Electronic System in Promoting the Quality of Nursing Care 结构化培训计划在电子系统转型中对提高护理质量的有效性
Pub Date : 2023-10-05 DOI: 10.34257/gjmrkvol23is6pg15
Ali M. Al Yasien, Dr. Abdulmajeed Al Shehah, Shini Cherian, Deirdre Hawkin, Mary Van Eck, Yamen A. Hamed, Manal Al Essa, Ahmed I. Alomar, Salem A. Al Shammari, Hameed J. Al Enazi
Background: In today’s dynamic health systems, technology plays an essential role in education and nursing practice. Therefore, it is necessary to study the changing role of nurses and highlight the need for appropriate information technology educational programs to integrate with the ever-increasing pace of technology. Nursing informatics helps improve vital nursing processes, such as documentation, which is a critical aspect of the profession and essential for effective patient care. Before electronic health records, nurses recorded patient information on charts, which could easily be mismanaged. Today, nursing informatics simplifies documentation and automates the transmission of patient data via connected devices to provide access for nurses, physicians, and patients.
背景:在当今动态的卫生系统中,技术在教育和护理实践中起着至关重要的作用。因此,有必要研究护士角色的变化,并强调需要适当的信息技术教育计划来与不断增长的技术步伐相结合。护理信息学有助于改善重要的护理过程,如文档,这是专业的一个关键方面,对有效的病人护理至关重要。在电子健康记录出现之前,护士将患者信息记录在图表上,这很容易管理不善。今天,护理信息学简化了文档,并通过连接的设备自动传输患者数据,为护士、医生和患者提供访问。
{"title":"The Effectiveness of a Structured Training Program in Transforming to an Electronic System in Promoting the Quality of Nursing Care","authors":"Ali M. Al Yasien, Dr. Abdulmajeed Al Shehah, Shini Cherian, Deirdre Hawkin, Mary Van Eck, Yamen A. Hamed, Manal Al Essa, Ahmed I. Alomar, Salem A. Al Shammari, Hameed J. Al Enazi","doi":"10.34257/gjmrkvol23is6pg15","DOIUrl":"https://doi.org/10.34257/gjmrkvol23is6pg15","url":null,"abstract":"Background: In today’s dynamic health systems, technology plays an essential role in education and nursing practice. Therefore, it is necessary to study the changing role of nurses and highlight the need for appropriate information technology educational programs to integrate with the ever-increasing pace of technology. Nursing informatics helps improve vital nursing processes, such as documentation, which is a critical aspect of the profession and essential for effective patient care. Before electronic health records, nurses recorded patient information on charts, which could easily be mismanaged. Today, nursing informatics simplifies documentation and automates the transmission of patient data via connected devices to provide access for nurses, physicians, and patients.","PeriodicalId":93101,"journal":{"name":"Global journal of medical research","volume":"168 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135546983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Global journal of medical research
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