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Tetradentate azo Schiff base Ni(II), Pd(II) and Pt(II) complexes: Synthesis, spectral properties, antibacterial activity, cytotoxicity and docking studies 四价偶氮席夫碱 Ni(II)、Pd(II) 和 Pt(II) 配合物:合成、光谱特性、抗菌活性、细胞毒性和对接研究
IF 1.2 4区 化学 Q3 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2023-11-29 DOI: 10.4314/bcse.v38i1.8
Hussein Abdulkadhim Hasan, Saad M. Mahdi, Hanaa Addai Ali
A new complexes of Ni(II), Pd(II), and Pt(II) have been synthesized from the reaction of Azo-Schiff base ligand (L1) that was prepared by the condensation firstly of salicylaldehyde with ethylene diamine in a 1:2 molar ratio and the prepared imine compound (S1) reacted with 2,5-dichloro aniline, and were employed in the preparation of complexes containing the metal ions Ni(II), Pd(II), and Pt(II). The structural characteristics of the synthesized compounds were investigated using UV-Vis, IR and NMR, molar conductance, elemental analysis, and mass spectroscopy. The results of the elemental analysis point to a 1:1 [M:L] stoichiometry. According to molar conductance studies, none of the prepared end products are electrolytic in nature. The complexes of Ni(II), Pd(II), and Pt(II) may have square planer geometry, according to spectral investigations. Then Pd(II), Ni(II), and Pt(II) complexes were evaluated for antimicrobial activity against different types strains of Gram-negative [Escherichia coli (ATCC 25922)] and positive bacteria [Staphylococcus aureus (ATCC 25923)] and showed good significant against these bacteria. The cytotoxic effect of the palladium complex on the prostatic malignant cell was examined via the PC3 cell line studied against normal cell WRL-68. The molecular docking of target microorganisms of these complexes will be studied by using MOE software. KEY WORDS: Salen ligand, Nickel(II), Palladium(II), Platinum(II), Complexes, bis azo-Schiff base Bull. Chem. Soc. Ethiop. 2024, 38(1), 99-111. DOI: https://dx.doi.org/10.4314/bcse.v38i1.8
首先将水杨醛与乙二胺以 1:2 的摩尔比缩合制备偶氮-希夫碱配体(L1),然后将制备的亚胺化合物(S1)与 2,5-二氯苯胺反应,合成了 Ni(II)、Pd(II)和 Pt(II) 的新配合物,并用于制备含有金属离子 Ni(II)、Pd(II)和 Pt(II) 的配合物。利用紫外-可见光谱、红外光谱、核磁共振、摩尔电导、元素分析和质谱对合成化合物的结构特征进行了研究。元素分析的结果表明其化学计量为 1:1 [M:L]。摩尔电导研究表明,所制备的最终产物都不具有电解性质。根据光谱研究,Ni(II)、Pd(II) 和 Pt(II) 的配合物可能具有方平面几何。然后,评估了 Pd(II)、Ni(II) 和 Pt(II) 复合物对不同类型的革兰氏阴性菌[大肠杆菌 (ATCC 25922)]和阳性菌[金黄色葡萄球菌 (ATCC 25923)]的抗菌活性,结果表明这些复合物对这些细菌具有良好的抗菌效果。通过 PC3 细胞系与正常细胞 WRL-68 的对比研究,考察了钯复合物对前列腺恶性细胞的细胞毒性作用。将使用 MOE 软件研究这些复合物与目标微生物的分子对接。 关键词:Salen 配体、镍(II)、钯(II)、铂(II)、配合物、双偶氮-Schiff 碱 Bull.Chem.Soc.2024, 38(1), 99-111.DOI: https://dx.doi.org/10.4314/bcse.v38i1.8
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引用次数: 0
Green synthesis of iron oxide nanoparticles from Spermacoce ocymoides Burm.f. plant extracts for targeted lung cancer A549 cell therapy 从 Spermacoce ocymoides Burm.f. 植物提取物中绿色合成氧化铁纳米粒子,用于肺癌 A549 细胞靶向治疗
IF 1.2 4区 化学 Q3 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2023-11-29 DOI: 10.4314/bcse.v38i1.10
T. Uma Rajalakshmi, C. Esaivani, T. Anantha Kumar, R. Mariselvam, G. Tamil Selvan, Zhen Zhang, Nouf M. Alyam, P. Mariselvi
The present study evaluated the synthesis of iron oxide nanoparticles using Spermacoce ocymoides Burm.f. plant extracts, and the effects of plant based iron oxide nanoparticles on A549 lung cancer cells were investigated to elucidate their impact on cellular morphology, mitochondrial function, and apoptotic pathways. Spermacoce ocymoides plant based iron oxide nanoparticles were characterised by X-ray diffraction, Atomic force microscopy, FTIR, and UV-Vis absorption spectroscopy. Iron oxide nanoparticle treatment caused considerable morphological alterations in A549 cells, including cell shrinkage, detachment, membrane blabbing, and distorted shape, consistent with cellular stress and potential apoptotic events. MMP analysis revealed a dose-dependent decrease in mitochondrial membrane potential, implying that nanoparticles have an effect on mitochondrial function. The presence of reactive oxygen species suggested that oxidative stress was involved in the cellular response to iron oxide nanoparticles. Additionally, DNA fragmentation analysis confirmed the activation of apoptotic pathways, with the nanoparticles themselves serving as a positive control for inducing apoptosis. The observed morphological changes, altered mitochondrial function, ROS production, and DNA fragmentation collectively point towards apoptotic cell death pathways being triggered by the nanoparticles. KEY WORDS: Spermacoce ocymoides, Iron oxide nanoparticles, A549 cells, Apoptotic Bull. Chem. Soc. Ethiop. 2024, 38(1), 123-134. DOI: https://dx.doi.org/10.4314/bcse.v38i1.10
本研究评估了利用 Spermacoce ocymoides Burm.f. 植物提取物合成氧化铁纳米粒子的情况,并研究了植物基氧化铁纳米粒子对 A549 肺癌细胞的影响,以阐明其对细胞形态、线粒体功能和凋亡途径的影响。通过 X 射线衍射、原子力显微镜、傅里叶变换红外光谱和紫外可见吸收光谱对 Spermacoce ocymoides 植物基氧化铁纳米粒子进行了表征。氧化铁纳米颗粒处理会导致 A549 细胞发生严重的形态学改变,包括细胞萎缩、脱落、膜脱落和形状扭曲,这与细胞应激和潜在的细胞凋亡事件一致。MMP 分析表明线粒体膜电位的降低与剂量有关,这意味着纳米颗粒对线粒体功能有影响。活性氧的存在表明,氧化应激参与了细胞对氧化铁纳米颗粒的反应。此外,DNA 片段分析证实了凋亡途径的激活,纳米粒子本身可作为诱导凋亡的阳性对照。观察到的形态学变化、线粒体功能改变、ROS产生和DNA片段化共同表明,纳米粒子触发了细胞凋亡途径。 关键词:Spermacoce ocymoides 氧化铁纳米颗粒 A549 细胞 凋亡 Bull.Chem.Soc.2024, 38(1), 123-134.DOI: https://dx.doi.org/10.4314/bcse.v38i1.10
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引用次数: 0
Synthesis and characterization of activated carbon from Asphodelus microcarpus in two steps 分两步从小檗中合成活性炭并确定其特性
IF 1.2 4区 化学 Q3 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2023-11-29 DOI: 10.4314/bcse.v38i1.15
Ourred Mohammed, Kaid Mhamed, Merine Houaria
The aim of the present work was to prepare an activated carbon from new precursor Asphodelus microcarpus using KOH as an impregnating agent, in two steps and in the absence of nitrogen. Its preparation requires a pre-carbonization at 500 °C for 60 min in order to obtain the char. Then activation of the char is realized by using KOH using as activating agent variable impregnation ratio: char/activating agent. Calcination is then carried out at 750 °C and 850 °C for 1 hour without azote. The determination of the optimum conditions is carried out by measuring the iodine number and that of methylene blue. The characterization of the chosen product is carried out by the following techniques: BET, FTIR-ATR, SEM and DRX. Under optimum conditions with mass ratio 1:4 at 750 °C (the calcination temperature), the specific surface area is equal to 1025.75 m2.g-1 and we obtain micro-meso activated carbon. The adsorption kinetics of dye chosen agrees with the pseudo-second-order model, and it appears that Freundlich (two parameters model) and Redlich-Peterson (three parameters model) describe better the adsorption data. Error analysis also showed that the Freunlich model better described the adsorption of Eriochrome Black T compared with the three parameter models. KEY WORDS: Asphodelus microcarpus, Two-stage activation process, Chemical activation, Adsorption, Dye   Bull. Chem. Soc. Ethiop. 2024, 38(1), 199-212. DOI: https://dx.doi.org/10.4314/bcse.v38i1.15
本研究的目的是使用 KOH 作为浸渍剂,在无氮条件下分两步从新的前驱体 Asphodelus microcarpus 中制备活性炭。制备过程需要在 500 °C 下预碳化 60 分钟,以获得炭。然后使用 KOH 作为活化剂,以不同的浸渍比例(炭/活化剂)对炭进行活化。然后在 750 °C 和 850 °C 下煅烧 1 小时,不使用偶氮。通过测量碘值和亚甲基蓝的碘值来确定最佳条件。通过以下技术对所选产品进行表征:BET、FTIR-ATR、SEM 和 DRX。在 750 °C (煅烧温度)、质量比为 1:4 的最佳条件下,比表面积等于 1025.75 m2.g-1,我们得到了微米级活性炭。所选染料的吸附动力学符合伪二阶模型,Freundlich(二参数模型)和 Redlich-Peterson(三参数模型)似乎能更好地描述吸附数据。误差分析也表明,与三参数模型相比,Freundlich 模型能更好地描述褐变黑 T 的吸附情况。 关键词:Asphodelus microcarpus、两阶段活化过程、化学活化、吸附、染料 Bull.Chem.Soc.2024, 38(1), 199-212.DOI: https://dx.doi.org/10.4314/bcse.v38i1.15
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引用次数: 0
Assembly of two luminescent cadmium(II) 4,4'-phosphini Co-dibenzoate coordination polymers 组装两种发光的 4,4'-磷酸二苯甲酸镉(II)配位聚合物
IF 1.2 4区 化学 Q3 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2023-11-29 DOI: 10.4314/bcse.v38i1.7
Zi-Hang Zou, Ning Tan, Emmanuel N. Nfor, Zhao-Xi Wang
Two new cadmium(II) coordination polymers [Cd(HL)(H2O)]·1.5H2O (1) and [Cd(HL)(4-bpmp)0.5]·2H2O (2) (H3L = 4,4'-phosphinicobis-dibenzoic acid, and 4-bpmp = N,N'-bis(4-pyridylmethyl)piperazine) have been synthesized by self-assembly of CdCl2 with 4,4'-phosphinicobis-dibenzoate, and N,N'-bis(4-pyridylmethyl)piperazine through solvothermal/hydrothermal method. Their structures were confirmed by X-ray single crystal diffraction, infrared spectrometer (IR), and powder X-ray diffraction (PXRD) and TGA techniques. Both compounds are in Pī space group and exhibited a 2D networks constructed from dinuclear [Cd2(POO)2] or paddle-wheel [Cd2(COO)2(POO)2] units, respectively. In 2, the Cd2+ is five-coordinated and shows a rare tetragonal pyramidal geometry. At room temperature, the compounds exhibit moderately intense blue and green fluorescence emission with peaks at 381 nm and 509 nm, respectively. KEY WORDS: Cadmium(II) compounds, Photoluminescence, Carboxyphosphinate ligand Bull. Chem. Soc. Ethiop. 2024, 38(1), 85-98. DOI: https://dx.doi.org/10.4314/bcse.v38i1.7
两种新的镉(II)配位聚合物[Cd(HL)(H2O)]-1.5H2O (1)和[Cd(HL)(4-bpmp)0.5]-2H2O(2)(H3L = 4,4'-膦酰基二苯甲酸,4-bpmp = N,N'-双(4-吡啶基甲基)哌嗪)是由 CdCl2 与 4,4'-膦酰基二苯甲酸和 N,N'-双(4-吡啶基甲基)哌嗪通过溶热/水热法自组装合成的。通过 X 射线单晶衍射、红外光谱仪、粉末 X 射线衍射和热重分析技术确认了它们的结构。这两种化合物都属于 Pī 空间群,分别由双核 [Cd2(POO)2] 或桨轮 [Cd2(COO)2(POO)2]单元构建成二维网络。在 2 中,Cd2+ 是五配位的,并呈现出罕见的四方金字塔几何形状。室温下,这些化合物分别在 381 nm 和 509 nm 处发出中等强度的蓝色和绿色荧光。 关键词:镉(II)化合物;光致发光;羧基膦酸配体 Bull.Chem.Soc.2024, 38(1), 85-98.DOI: https://dx.doi.org/10.4314/bcse.v38i1.7
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引用次数: 0
A green HPLC method for the determination of torasemide in pharmaceutical dosage forms: Development, validation, and greenness assessment 测定药物剂型中托拉塞米的绿色高效液相色谱法:开发、验证和绿色评估
IF 1.2 4区 化学 Q3 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2023-11-29 DOI: 10.4314/bcse.v38i1.2
Erten Akbel, I. Bulduk, Süleyman Gökçe
Two HPLC methods were developed for the determination of torasemide in pharmaceutical products. In the first method, a C18 column whose temperature was kept constant at 25 °C was used. A combination of 0.1% formic acid solution in water and acetonitrile (50/50, v/v) was used as the mobile phase, and isocratic elution was performed at a flow rate of 1.0 mL min-1. Detection was carried out at 288 nm using the UV detector. Although all other conditions are the same as in the first method, the only difference in the second method is that ethanol is used instead of acetonitrile as the organic modifier in the mobile phase. HPLC methods were validated in accordance with ICH guidelines. Correlation coefficients were greater than 0.999 in the concentration range of 5-30 mg mL-1. Later, HPLC methods were applied to pharmaceutical formulations. Results were compared using the student (t) test for means and the Fischer (F) test for standard deviations. No significant differences were observed between methods. Additionally, a greenness evaluation of the developed methods was carried out using AGREE software. As a result, the latter method was proposed as an excellent eco-friendly alternative for the determination of torasemide in pharmaceuticals. KEY WORDS: Green HPLC, Analytical method, Torasemide, Pharmaceuticals   Bull. Chem. Soc. Ethiop. 2024, 38(1), 11-25. DOI: https://dx.doi.org/10.4314/bcse.v38i1.2
为测定药品中的托拉塞米,我们开发了两种高效液相色谱法。第一种方法采用 C18 色谱柱,色谱柱温度恒定在 25 °C。流动相为 0.1% 甲酸水溶液和乙腈(体积比为 50/50),以 1.0 mL/min-1 的流速进行等度洗脱。使用紫外检测器在 288 纳米波长下进行检测。虽然所有其他条件都与第一种方法相同,但第二种方法的唯一不同之处在于流动相中使用了乙醇而非乙腈作为有机改性剂。高效液相色谱法根据 ICH 指南进行了验证。在 5-30 mg mL-1 的浓度范围内,相关系数大于 0.999。随后,HPLC 方法被应用于药物制剂。结果比较采用了学生(t)检验(均值)和费舍尔(F)检验(标准偏差)。不同方法之间未发现明显差异。此外,还使用 AGREE 软件对所开发的方法进行了绿色评估。结果表明,后一种方法被认为是测定药物中托拉塞米的最佳环保替代方法。 关键词: 绿色 HPLC 分析方法 托拉塞米 药品 Bull.Chem.Soc.2024, 38(1), 11-25.DOI: https://dx.doi.org/10.4314/bcse.v38i1.2
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引用次数: 0
Evaluation of improved corrosion resistance of Zn alloy as electrode material by Co3O4 coatings 评估用 Co3O4 涂层改善锌合金电极材料的耐腐蚀性能
IF 1.2 4区 化学 Q3 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2023-11-29 DOI: 10.4314/bcse.v38i1.18
R. J. Golden, Renjith Nimal, D. F. Melvin, K. Balasubramanian, J. Sunil
This work uses the sonochemical method to represent synthesized cobalt oxide nanoparticles (Co3O4) and analysed using different techniques. The X-ray diffraction analysis (XRD) and Fourier-transform infrared spectroscopy (FTIR) examinations of the synthesized nanoparticles confirmed their cubic structure and average crystallite size of 21.3 nm. The spherical surface shape and presence of components with a particle size of 25.3 nm were revealed. Scanning probe microscopy (SPM) methods analysed the Co3O4 coated plates' surface characteristics, including roughness and topographical ideas. An aqueous electrolyte medium (6 M KOH) was used to investigate the electrochemical corrosion behaviour of Co3O4-coated plates. According to the Tafel plot, coating Zn plates with a high surface area and mesoporous Co3O4 in KOH electrolytes greatly reduced the corrosion of the plates. The coated plates are thermally treated up to 600℃. The temperature-dependent anticorrosive properties of Co3O4 NPs are evaluated. KEY WORDS: Co3O4, Zn plate, Tafel plot, Linear sweep voltammetry, Anti-corrosive performance, Nanoindentation Bull. Chem. Soc. Ethiop. 2024, 38(1), 241-253. DOI: https://dx.doi.org/10.4314/bcse.v38i1.18
本研究采用声化学方法表示合成的氧化钴纳米粒子(Co3O4),并使用不同的技术对其进行分析。对合成的纳米粒子进行的 X 射线衍射分析(XRD)和傅立叶变换红外光谱(FTIR)检测证实了其立方结构和 21.3 纳米的平均晶粒尺寸。球形表面形状和粒径为 25.3 纳米的成分的存在也得到了证实。扫描探针显微镜(SPM)方法分析了 Co3O4 涂层板的表面特征,包括粗糙度和地形特征。使用水性电解质介质(6 M KOH)研究了 Co3O4 涂层板的电化学腐蚀行为。根据 Tafel 图,在 KOH 电解质中涂覆高比表面和介孔 Co3O4 的锌板大大减少了对锌板的腐蚀。涂层板经热处理后的温度可达 600℃。评估了 Co3O4 NPs 随温度变化的防腐性能。 关键词:Co3O4、Zn 板、塔菲尔图、线性扫描伏安法、抗腐蚀性能、纳米压痕 Bull.Chem.Soc.2024, 38(1), 241-253.DOI: https://dx.doi.org/10.4314/bcse.v38i1.18
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引用次数: 0
Optimization of parameters for bio-ethanol production from sweet sorghum (Sorghum bicolor (L.) Moench) stalk juice and finger millet malt using Taguchi method 用田口方法优化甜高粱(Sorghum bicolor (L.) Moench)茎汁和小米麦芽生产生物乙醇的参数
IF 1.2 4区 化学 Q3 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2023-11-29 DOI: 10.4314/bcse.v38i1.5
Dolphene Okoth, Stephen Otieno, Francis Kiema, David Onyango, C. Kowenje
Bio-ethanol is a promising renewable energy but its production is expensive from high cost of feedstocks. In this study, sweet sorghum (Sorghum bicolor (L.) Moench) stalk juice was investigated for bio-ethanol production. Most reports on bio-ethanol productions use commercial Saccharomyces cerevisiae as yeast. However, this study used finger millet (Eleusine coracana) malt with already high adaptation to local conditions and high economic viability as it is being utilized by the indigenous communities. Five sweet sorghum varieties of IESV-92001-DL (V1), NTJ (V2), 15233-IESV (V3), 92008-DJ (V4) and IESV-92028-DL (V5) were planted at 0°3'45.4644" North, 34°17'16.1052" South, in Kenya. °Brix content of juice was determined at 11th to 16th weeks after sowing. Highest °Brix for all varieties were at 15th week where V1 was highest at 22.07. V1 was then harvested for the juice. Factors affecting fermentation; temperature, time, pH and yeast to substrate ratio were optimized using Taguchi method and were obtained as 30 ℃, 48 hours, pH 5 and 5 g/L, respectively. Kinetics parameters of Vmax and Km were 0.35 g/L/h and 12.56 g/L, respectively. The optimized and kinetic parameters were within literature values and therefore finger millet malt has a great potential, as a substitute yeast source, in commercial bio-ethanol production. KEY WORDS: Bio-ethanol, Sweet sorghum juice, Taguchi method Bull. Chem. Soc. Ethiop. 2024, 38(1), 55-67. DOI: https://dx.doi.org/10.4314/bcse.v38i1.5
生物乙醇是一种前景广阔的可再生能源,但由于原料成本高昂,其生产成本也很高。本研究对甜高粱(Sorghum bicolor (L.) Moench)茎汁进行了生物乙醇生产研究。大多数关于生物乙醇生产的报告都使用商业酵母菌作为酵母。然而,这项研究使用的是指粟(Eleusine coracana)麦芽,这种麦芽对当地条件的适应性已经很强,而且经济可行性也很高,因为土著社区正在使用这种麦芽。在肯尼亚北纬 0°3'45.4644"、南纬 34°17'16.1052 "种植了五个甜高粱品种:IESV-92001-DL(V1)、NTJ(V2)、15233-IESV(V3)、92008-DJ(V4)和 IESV-92028-DL(V5)。果汁的 °Brix 含量在播种后第 11 至 16 周测定。所有品种在第 15 周时的白利糖度最高,其中 V1 的白利糖度最高,为 22.07。然后收获 V1 果汁。采用田口方法对影响发酵的因素:温度、时间、pH 值和酵母与底物的比例进行了优化,结果分别为 30 ℃、48 小时、pH 值 5 和 5 克/升。动力学参数 Vmax 和 Km 分别为 0.35 g/L/h 和 12.56 g/L。优化参数和动力学参数均在文献值范围内,因此,作为酵母源的替代品,小米麦芽在商业生物乙醇生产中具有很大的潜力。 关键词:生物乙醇、甜高粱汁、田口法 Bull.Chem.Soc. Ethiop.2024, 38(1), 55-67.DOI: https://dx.doi.org/10.4314/bcse.v38i1.5
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引用次数: 0
Synthesis, crystal structure, DFT calculation and Hirshfeld surface analysis of N-(4-methyl phenyl)-2-(3-nitro-benzamido) benzamide N-(4-甲基苯基)-2-(3-硝基苯甲酰胺基)苯甲酰胺的合成、晶体结构、DFT 计算和 Hirshfeld 表面分析
IF 1.2 4区 化学 Q3 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2023-11-29 DOI: 10.4314/bcse.v38i1.17
Mzgin Mohammed Ayoob, Farouq Emam Hawaiz
A new bis amide N-(4-methylphenyl)-2-(3-nitrobenzamide) benzamide was synthesized from a ring-opening reaction of 2-(3-nitrophenyl)-4H-benzoxazin-4-one, with 4-methyl aniline in a shorten reaction time (1.0 min) and characterized using different spectroscopic techniques (FT-IR, 1H-NMR, 13C-NMR) and single-crystal X-ray diffraction (XRD). In the crystal lattice, the molecules are linked by N–H···O and C–H···O hydrogen bonds. The Hirshfeld surface analysis mapped over shape index, curvedness indices, dnorm revealed strong H...H and H...O/O...H and intermolecular connections a key contributors to crystal packing structure. Density functional theory (DFT) calculations were applied with B3LYP/6-311G(d) level to provide theoretical data along with HOMO-LUMO electronic energy with the MEP map. KEY WORDS: Benzamide, Crystal structure, DFT calculation, Hirshfeld surface Bull. Chem. Soc. Ethiop. 2024, 38(1), 229-239. DOI: https://dx.doi.org/10.4314/bcse.v38i1.17
一种新的双酰胺 N-(4-甲基苯基)-2-(3-硝基苯甲酰胺)苯甲酰胺是由 2-(3-硝基苯基)-4H-苯并恶嗪-4-酮与 4-甲基苯胺在较短的反应时间(1.0 分钟)内开环反应合成的,并利用不同的光谱技术(傅立叶变换红外光谱、1H-核磁共振、13C-核磁共振)和单晶 X 射线衍射(XRD)对其进行了表征。在晶格中,分子通过 N-H-O 和 C-H-O 氢键相连。对形状指数、弯曲指数和 dnorm 进行的 Hirshfeld 表面分析表明,H...H 和 H...O/O...H 以及分子间的强连接是晶体堆积结构的关键因素。采用 B3LYP/6-311G(d) 水平进行了密度泛函理论(DFT)计算,提供了理论数据以及 HOMO-LUMO 电子能量和 MEP 图。 关键词:苯甲酰胺 晶体结构 DFT 计算 Hirshfeld 表面 Bull.Chem.Soc.2024, 38(1), 229-239.DOI: https://dx.doi.org/10.4314/bcse.v38i1.17
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引用次数: 0
Biogenic synthesis of silver nanoparticles using essential oil of aerial part of cyclospermum leptophyllum and their application in colorimetric determination of metallic ions 利用仙客来气生部分的精油合成银纳米粒子及其在金属离子比色测定中的应用
IF 1.2 4区 化学 Q3 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2023-11-29 DOI: 10.4314/bcse.v38i1.16
Yilma Hunde Gonfa, Mesfin Getachew Tadesse, Samuel Abicho Kabeto, Fekade Beshah Tessema, Archana Bachheti, Kundan Kumar Chaubey, Rakesh Kumar Bachheti
The focus of this research was to synthesize biogenic silver nanoparticles (AgNPs) using the essential oil of the aerial part of Cyclospermum leptophyllum (CLEO) and investigate their colorimetric determination of metallic ions. In the synthesis of CLEO mediated AgNPs (CLEO-AgNPs), the one-factor-at-a-time method was used to optimize the reaction parameters. Ultraviolet-visible (UV-Vis) peak of CLEO-AgNPs was determined at 426 nm. Fourier transform-infrared (FTIR) spectra analysis identified the functional groups participating in the bio-reducing, capping, and stabilizing processes in the CLEO-AgNPs synthesis. Scanning electron microscope (SEM) image demonstrated the predominately spherical shape and the average size of 70.86+1.80 nm of CLEO-AgNPs. Energy dispersive X-ray spectroscopy (EDX) peak profile depicted the presence of Ag elements in CLEO-AgNPs. The X-ray diffraction (XRD) peaks observed at 38.5°, 44°, 65°, and 77° which represent Ag(111), Ag(200), Ag(220), and Ag(311) lattice faces, respectively. The average zeta nanosize, zeta potential, and polydispersity index of CLEO-AgNPs were determined as 69.70 nm, -43.5 mV, and 0.256, respectively. The stability test exhibited the prolonged storage stability of CLEO-AgNPs for over six months at room temperature. CLEO-AgNPs demonstrated the potential colorimetric detection of K+, Mg2+, Al3+, Cr6+, Mn2+, Fe3+, Ni2+, Cu2+, Zn2+, Hg2+, Pb2+, and Cd2+ ions in the real samples. KEY WORDS: Cyclospermum leptophyllum, Essential oil, Biogenic silver nanoparticles, Bio-reductants, Colorimetric detection   Bull. Chem. Soc. Ethiop. 2024, 38(1), 213-228. DOI: https://dx.doi.org/10.4314/bcse.v38i1.16
本研究的重点是利用仙客来(Cyclospermum leptophyllum,CLEO)气生部分的精油合成生物银纳米粒子(AgNPs),并研究其对金属离子的比色测定。在 CLEO 介导的 AgNPs(CLEO-AgNPs)的合成过程中,采用了一次一因素法优化反应参数。CLEO-AgNPs 的紫外可见(UV-Vis)峰在 426 纳米处。傅立叶变换红外光谱分析确定了参与 CLEO-AgNPs 合成过程中生物还原、封盖和稳定过程的官能团。扫描电子显微镜(SEM)图像显示,CLEO-AgNPs 主要呈球形,平均尺寸为 70.86+1.80 nm。能量色散 X 射线光谱(EDX)峰谱图显示 CLEO-AgNPs 中存在银元素。在 38.5°、44°、65° 和 77°处观察到的 X 射线衍射 (XRD) 峰分别代表 Ag(111)、Ag(200)、Ag(220) 和 Ag(311) 晶格面。经测定,CLEO-AgNPs 的平均 zeta 纳米尺寸、zeta 电位和多分散指数分别为 69.70 nm、-43.5 mV 和 0.256。稳定性测试表明,CLEO-AgNPs 在室温下具有超过六个月的长期储存稳定性。CLEO-AgNPs具有比色检测实际样品中K+、Mg2+、Al3+、Cr6+、Mn2+、Fe3+、Ni2+、Cu2+、Zn2+、Hg2+、Pb2+和Cd2+离子的潜力。 关键词: Cyclospermum leptophyllum、精油、生物银纳米颗粒、生物还原剂、比色检测 Bull.Chem.Soc.2024, 38(1), 213-228.DOI: https://dx.doi.org/10.4314/bcse.v38i1.16
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引用次数: 0
Algerian wild green carob (Ceratonia siliqua L.): Physicochemical characteristics and antioxidant potency 阿尔及利亚野生绿角豆(Ceratonia siliqua L.):理化特性和抗氧化能力
IF 1.2 4区 化学 Q3 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2023-11-29 DOI: 10.4314/bcse.v38i1.14
Rima Ayad, R. Ayad, Latifa Zineddine, Nour El Houda Berghida
The main purpose of this study was to determine the proximate composition and physicochemical properties of Algerian wild green carob collected from three separate locations in Jijel province (northeast of Algeria), as well as to investigate its antioxidant potency. The results showed that the three samples were substantially comparable in terms of proximate compositions and physicochemical attributes. They have an acidic pH range and a very low fat content. In terms of phytochemical properties, Texenna green pods had the highest levels of polyphenols, flavonoids, and flavonols, with concentrations of 87.10 ± 0.07 μg GAE/mg DM, 4.90 ± 0.06 μg QE/mg DM, and 37.0 ± 0.19 μg QE/mg DM, respectively. Furthermore, the total antioxidant capacity of the methanolic extracts was determined using the phosphomolybdate method and found to be 154.62 µg AAE/mg DM. These promising findings revealed that unripe Ceratonia siliqua L. from the Texenna region is a rich source of natural antioxidants that could be employed more broadly in functional food formulations. KEY WORDS: Ceratonia siliqua L., Unripe pods, Proximate composition, Physicochemical properties, Bioactive compounds, Antioxidant potency Bull. Chem. Soc. Ethiop. 2024, 38(1), 187-198. DOI: https://dx.doi.org/10.4314/bcse.v38i1.14
本研究的主要目的是确定从吉杰勒省(阿尔及利亚东北部)三个不同地点采集的阿尔及利亚野生绿角豆树的近似成分和理化特性,并研究其抗氧化能力。结果表明,这三种样本的近似成分和理化属性基本相当。它们的 pH 值呈酸性,脂肪含量很低。在植物化学特性方面,德克森纳青豆荚的多酚、类黄酮和黄酮醇含量最高,分别为 87.10 ± 0.07 μg GAE/mg DM、4.90 ± 0.06 μg QE/mg DM 和 37.0 ± 0.19 μg QE/mg DM。此外,采用磷钼酸盐法测定了甲醇提取物的总抗氧化能力,发现其为 154.62 µg AAE/mg DM。这些有前景的研究结果表明,德森纳地区未熟的 Ceratonia siliqua L. 是天然抗氧化剂的丰富来源,可更广泛地应用于功能性食品配方中。 关键字:Ceratonia siliqua L.,未成熟豆荚,近似成分,理化性质,生物活性化合物,抗氧化效力 Bull.Chem.Soc.2024, 38(1), 187-198.DOI: https://dx.doi.org/10.4314/bcse.v38i1.14
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Bulletin of the Chemical Society of Ethiopia
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