Pub Date : 2023-11-13DOI: 10.1021/cen-10137-cover4
None Mark Peplow, special to C&EN
In 2018, reports in the mainstream media about plastic pollution reached a crescendo. Dead whales with bellies full of plastic trash appeared on the pages of National Geographic . Scientists voiced concerns about microplastics in our food, water, and air. Images of tropical bays choked with plastic debris offered visceral proof that our waste management systems were failing. Samantha Anderson was a PhD student at the Swiss Federal Institute of Technology, Lausanne (EPFL), at the time , and she vividly remembers how these reports spurred her and her colleagues to take action. “We just decided that we were going to try and tackle it with chemistry and chemical engineering, because that’s what we knew,” she says. With her EPFL lab mates Christopher Ireland and Bardiya Valizadeh, Anderson developed a process for recycling polyethylene terephthalate (PET) in complex waste streams that most recyclers reject. In 2020, the trio cofounded DePoly to
2018年，主流媒体对塑料污染的报道达到高潮。肚子里塞满塑料垃圾的死鲸出现在《国家地理》杂志的页面上。科学家们对食物、水和空气中的微塑料表示担忧。充斥着塑料碎片的热带海湾的图片，是我们的废物管理系统失灵的有力证据。萨曼莎·安德森当时是瑞士洛桑联邦理工学院(EPFL)的一名博士生，她清楚地记得这些报告是如何激励她和她的同事采取行动的。她说:“我们决定尝试用化学和化学工程来解决这个问题，因为这是我们所知道的。”安德森和她在EPFL实验室的同事克里斯托弗·爱尔兰(Christopher Ireland)和巴蒂亚·瓦里扎德(Bardiya Valizadeh)一起，开发了一种从复杂的废物流中回收聚对苯二甲酸乙二醇酯(PET)的方法，大多数回收商都拒绝这种方法。2020年，三人共同创立了DePoly to
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Pub Date : 2023-11-13DOI: 10.1021/cen-10137-buscon2
None Alex Scott
Many of Europe’s biggest chemical producers—including the German firms BASF, Covestro, Evonik Industries, and Lanxess—have reported declining sales and net losses for the third quarter. Europe’s chemical sector is now firmly in cost-cutting mode, and some companies are closing manufacturing plants because of ongoing soft demand for their products. BASF, still the world’s largest chemical company, recorded a loss of $264 million for the third quarter, compared with earnings of $962 million in the year-earlier period, and sales of $16.2 billion, down 28%. The German major cites considerably lower prices for products sold by its materials, chemicals, and surface technologies businesses and lower sales volumes across the board. BASF announced measures to cut costs by about $215 million annually, adding to plans to cut costs by more than $750 million per year by 2027. The firm plans to reduce its capital investments over the next 5 years by about $4.3
{"title":"Industry profits evaporate in Europe","authors":"None Alex Scott","doi":"10.1021/cen-10137-buscon2","DOIUrl":"https://doi.org/10.1021/cen-10137-buscon2","url":null,"abstract":"Many of Europe’s biggest chemical producers—including the German firms BASF, Covestro, Evonik Industries, and Lanxess—have reported declining sales and net losses for the third quarter. Europe’s chemical sector is now firmly in cost-cutting mode, and some companies are closing manufacturing plants because of ongoing soft demand for their products. BASF, still the world’s largest chemical company, recorded a loss of $264 million for the third quarter, compared with earnings of $962 million in the year-earlier period, and sales of $16.2 billion, down 28%. The German major cites considerably lower prices for products sold by its materials, chemicals, and surface technologies businesses and lower sales volumes across the board. BASF announced measures to cut costs by about $215 million annually, adding to plans to cut costs by more than $750 million per year by 2027. The firm plans to reduce its capital investments over the next 5 years by about $4.3","PeriodicalId":9517,"journal":{"name":"C&EN Global Enterprise","volume":"29 17","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136281524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-13DOI: 10.1021/cen-10137-cover10
None Bethany Halford
Cement holds the modern world together, but it lacks the allure of high-tech materials. “The stuff is gray,” says Yet-Ming Chiang , a professor of ceramics and materials science at the Massachusetts Institute of Technology. “You would be forgiven for thinking it’s kind of dull and boring.” But it’s not for Chiang and Leah Ellis, cofounders of Sublime Systems . They say finding a new way to make cement is necessary to solve one of the planet’s most pressing problems: the carbon dioxide emissions that are driving climate change. Cement, or calcium silicate hydrate, binds rocks and sand together to form concrete. Worldwide, cement companies make roughly 4 billion metric tons (t) of the stuff annually, according to the US Geological Survey. By some estimates, cement production accounts for as much as 8% of global CO 2 emissions . About half that massive belch of CO 2 is an unavoidable
水泥将现代世界连接在一起，但它缺乏高科技材料的吸引力。“这些东西是灰色的，”麻省理工学院陶瓷和材料科学教授蒋yet - ming Chiang说。“如果你认为它有点枯燥和无聊，那是可以理解的。”但对于Sublime Systems的联合创始人蒋和利亚·埃利斯(Leah Ellis)来说，情况并非如此。他们说，找到一种新的水泥制造方法对于解决地球上最紧迫的问题之一是必要的:推动气候变化的二氧化碳排放。水泥，或水合硅酸钙，将岩石和沙子粘合在一起形成混凝土。根据美国地质调查局的数据，全球水泥公司每年生产大约40亿吨水泥。据估计，水泥生产占全球二氧化碳排放量的8%。大约一半的二氧化碳是不可避免的
{"title":"Sublime Systems","authors":"None Bethany Halford","doi":"10.1021/cen-10137-cover10","DOIUrl":"https://doi.org/10.1021/cen-10137-cover10","url":null,"abstract":"Cement holds the modern world together, but it lacks the allure of high-tech materials. “The stuff is gray,” says Yet-Ming Chiang , a professor of ceramics and materials science at the Massachusetts Institute of Technology. “You would be forgiven for thinking it’s kind of dull and boring.” But it’s not for Chiang and Leah Ellis, cofounders of Sublime Systems . They say finding a new way to make cement is necessary to solve one of the planet’s most pressing problems: the carbon dioxide emissions that are driving climate change. Cement, or calcium silicate hydrate, binds rocks and sand together to form concrete. Worldwide, cement companies make roughly 4 billion metric tons (t) of the stuff annually, according to the US Geological Survey. By some estimates, cement production accounts for as much as 8% of global CO 2 emissions . About half that massive belch of CO 2 is an unavoidable","PeriodicalId":9517,"journal":{"name":"C&EN Global Enterprise","volume":"29 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136281531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-13DOI: 10.1021/cen-10137-comment1
None Diane Krone, chair, ACS Committee on Committees
Council-related committees have an important role in representing the perspective of the core membership of the American Chemical Society and contribute to governance decisions. Over the past few years, the Committee on Committees (ConC) has been reviewing the committee structure and the appointment process as it strives to fulfill its mission to ensure that ACS committees are inclusive, optimally organized, resourced, and engaged. As part of our process of looking for opportunities to improve the committee system, ConC partnered with McKinley Advisors, a consulting group with knowledge of ACS and other organizations in the nonprofit space, to review current committee structures and functions and to provide actionable recommendations that support the following ideal future: The portfolio of ACS committees and related governance processes reflects the current and anticipated needs of the society. ACS committees effectively collaborate to advance the mission and vision of the society. The membership, participation, and leadership
{"title":"We are stronger when we listen and smarter when we share","authors":"None Diane Krone, chair, ACS Committee on Committees","doi":"10.1021/cen-10137-comment1","DOIUrl":"https://doi.org/10.1021/cen-10137-comment1","url":null,"abstract":"Council-related committees have an important role in representing the perspective of the core membership of the American Chemical Society and contribute to governance decisions. Over the past few years, the Committee on Committees (ConC) has been reviewing the committee structure and the appointment process as it strives to fulfill its mission to ensure that ACS committees are inclusive, optimally organized, resourced, and engaged. As part of our process of looking for opportunities to improve the committee system, ConC partnered with McKinley Advisors, a consulting group with knowledge of ACS and other organizations in the nonprofit space, to review current committee structures and functions and to provide actionable recommendations that support the following ideal future: The portfolio of ACS committees and related governance processes reflects the current and anticipated needs of the society. ACS committees effectively collaborate to advance the mission and vision of the society. The membership, participation, and leadership","PeriodicalId":9517,"journal":{"name":"C&EN Global Enterprise","volume":"25 12","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136282269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-13DOI: 10.1021/cen-10137-buscon1
None Matt Blois
As consumer pressure and government policies push chemical firms to reduce the use of petroleum feedstocks, the green chemistry company Solugen is planning to significantly increase production of its biobased chemicals with a new facility. The new plant will be located next to an ADM complex in Marshall, Minnesota, that produces dextrose, which Solugen will use as a feedstock. Its process coproduces hydrogen peroxide and the organic acids glucaric and gluconic acid. Solugen CEO Gaurab Chakrabarti says the companies will also work together to develop new products and new markets. “ADM has a lot of customers that we could sell the glucaric acid products into,” he says. Chakrabarti cofounded Solugen in 2016 to commercialize an enzyme he discovered while in an MD-PhD program. The company has since raised more than $640 million from investors. At an existing facility in Houston, Solugen produces about 12,000 metric tons (t) per year of
{"title":"Solugen joins with ADM to expand biobased chemical production","authors":"None Matt Blois","doi":"10.1021/cen-10137-buscon1","DOIUrl":"https://doi.org/10.1021/cen-10137-buscon1","url":null,"abstract":"As consumer pressure and government policies push chemical firms to reduce the use of petroleum feedstocks, the green chemistry company Solugen is planning to significantly increase production of its biobased chemicals with a new facility. The new plant will be located next to an ADM complex in Marshall, Minnesota, that produces dextrose, which Solugen will use as a feedstock. Its process coproduces hydrogen peroxide and the organic acids glucaric and gluconic acid. Solugen CEO Gaurab Chakrabarti says the companies will also work together to develop new products and new markets. “ADM has a lot of customers that we could sell the glucaric acid products into,” he says. Chakrabarti cofounded Solugen in 2016 to commercialize an enzyme he discovered while in an MD-PhD program. The company has since raised more than $640 million from investors. At an existing facility in Houston, Solugen produces about 12,000 metric tons (t) per year of","PeriodicalId":9517,"journal":{"name":"C&EN Global Enterprise","volume":"28 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136282598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-13DOI: 10.1021/cen-10137-cover2
None Laura Howes
There are many proteins involved in making people sick, but right now, small-molecule drugs target only a small fraction of them. The San Diego–based start-up Belharra Therapeutics wants to go after a wider swath, focusing on proteins that have never been targeted by a drug. The story of Belharra, which came out of stealth at the beginning of this year, begins with Christopher Parker, a chemist at Scripps Research in California. As a postdoctoral scholar in Benjamin Cravatt’s lab at the same institute, Parker worked to build techniques for discovering pockets on proteins where drugs could bind. Parker continued that work when he started his own lab in 2018. He took the techniques he was working on to his Scripps colleague John Teijaro, an expert in immunology and persistent viral infections, and they had success binding Parker’s chemical probes to pockets on notoriously tricky immune proteins. Parker and Teijaro went
{"title":"Belharra Therapeutics","authors":"None Laura Howes","doi":"10.1021/cen-10137-cover2","DOIUrl":"https://doi.org/10.1021/cen-10137-cover2","url":null,"abstract":"There are many proteins involved in making people sick, but right now, small-molecule drugs target only a small fraction of them. The San Diego–based start-up Belharra Therapeutics wants to go after a wider swath, focusing on proteins that have never been targeted by a drug. The story of Belharra, which came out of stealth at the beginning of this year, begins with Christopher Parker, a chemist at Scripps Research in California. As a postdoctoral scholar in Benjamin Cravatt’s lab at the same institute, Parker worked to build techniques for discovering pockets on proteins where drugs could bind. Parker continued that work when he started his own lab in 2018. He took the techniques he was working on to his Scripps colleague John Teijaro, an expert in immunology and persistent viral infections, and they had success binding Parker’s chemical probes to pockets on notoriously tricky immune proteins. Parker and Teijaro went","PeriodicalId":9517,"journal":{"name":"C&EN Global Enterprise","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136283226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-13DOI: 10.1021/cen-10137-polcon1
None Britt E. Erickson
Over 50 years after determining that brominated vegetable oil (BVO) is no longer generally recognized as safe (GRAS), the US Food and Drug Administration is proposing to ban the food ingredient. BVO is not safe in food in any amount, the agency announced Nov. 2. BVO was once widely used as an emulsifier in sodas and sports drinks to keep citrus flavoring from floating to the top. Many beverage manufacturers stopped using the ingredient about 10 years ago because of health concerns. Studies in laboratory animals show increased levels of bromine in some tissues and adverse effects on the thyroid after oral exposure to the chemical. The FDA declared in 1970 that BVO is no longer GRAS, though it still allows the use of small amounts as a food additive. Since then, the agency has “continued to study it to understand any potential health impacts,” James Jones, the FDA’s deputy
{"title":"FDA seeks to ban brominated vegetable oil","authors":"None Britt E. Erickson","doi":"10.1021/cen-10137-polcon1","DOIUrl":"https://doi.org/10.1021/cen-10137-polcon1","url":null,"abstract":"Over 50 years after determining that brominated vegetable oil (BVO) is no longer generally recognized as safe (GRAS), the US Food and Drug Administration is proposing to ban the food ingredient. BVO is not safe in food in any amount, the agency announced Nov. 2. BVO was once widely used as an emulsifier in sodas and sports drinks to keep citrus flavoring from floating to the top. Many beverage manufacturers stopped using the ingredient about 10 years ago because of health concerns. Studies in laboratory animals show increased levels of bromine in some tissues and adverse effects on the thyroid after oral exposure to the chemical. The FDA declared in 1970 that BVO is no longer GRAS, though it still allows the use of small amounts as a food additive. Since then, the agency has “continued to study it to understand any potential health impacts,” James Jones, the FDA’s deputy","PeriodicalId":9517,"journal":{"name":"C&EN Global Enterprise","volume":"29 26","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136281519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-13DOI: 10.1021/cen-10137-editorial
None Michael McCoy
For most of the 9 years that C&EN has published its 10 Start-Ups to Watch feature—which appears this week on page 16—we’ve assessed drug and materials companies by separate financial standards. Start-ups focused on drugs typically raise much more money than materials firms in series A or other early funding rounds. For example, Alltrna, one of the three drug discovery firms we profiled last year, had $50 million in investor funding when it launched in 2021. The other two each raked in $100 million or more in their early investment rounds. By contrast, the chemical, agricultural, and clean technology start-ups we profiled were lucky to hit $30 million in their series A investment rounds, the stage in which companies typically transition from a promising concept to a full-fledged business. Sure, 10 companies are a small sample. But figures from the venture capital data firm PitchBook point to the same dichotomy.
{"title":"Drugs versus chemicals","authors":"None Michael McCoy","doi":"10.1021/cen-10137-editorial","DOIUrl":"https://doi.org/10.1021/cen-10137-editorial","url":null,"abstract":"For most of the 9 years that C&EN has published its 10 Start-Ups to Watch feature—which appears this week on page 16—we’ve assessed drug and materials companies by separate financial standards. Start-ups focused on drugs typically raise much more money than materials firms in series A or other early funding rounds. For example, Alltrna, one of the three drug discovery firms we profiled last year, had $50 million in investor funding when it launched in 2021. The other two each raked in $100 million or more in their early investment rounds. By contrast, the chemical, agricultural, and clean technology start-ups we profiled were lucky to hit $30 million in their series A investment rounds, the stage in which companies typically transition from a promising concept to a full-fledged business. Sure, 10 companies are a small sample. But figures from the venture capital data firm PitchBook point to the same dichotomy.","PeriodicalId":9517,"journal":{"name":"C&EN Global Enterprise","volume":"68 31","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136282005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-13DOI: 10.1021/cen-10137-polcon3
None Krystal Vasquez
The US Environmental Protection Agency has agreed to hear a petition by the Yurok, Port Gamble S’Klallam, and Puyallup tribes calling for the agency to regulate the use of N -(1,3-dimethylbutyl)- N ’-phenyl- p -phenylenediamine, known as 6PPD, in tires. The compound is linked to mass die-offs of coho salmon , which are central to the cultures, diets, and economies of these three tribes and important to other communities on the West Coast. In a response to the petition , the EPA says that in the coming months it will issue an advance notice of proposed rulemaking for 6PPD and begin gathering data to better understand the health and environmental risks associated with the chemical and a by-product, 6PPD-quinone. The agency also plans to finalize a rule under the Toxic Substances Control Act that will require manufacturers and importers of 6PPD to report any unpublished health and safety studies on
美国环境保护署已经同意听取由Yurok, Port Gamble S ' klallam和Puyallup部落提出的请愿书，该请愿书要求该机构对N -(1,3-二甲基丁基)- N ' -苯基-对苯二胺(称为6PPD)在轮胎中的使用进行监管。这种化合物与银鲑的大规模死亡有关，银鲑是这三个部落的文化、饮食和经济的核心，对西海岸的其他社区也很重要。在对请愿书的回应中，环保署表示，在接下来的几个月里，它将发布一份关于6PPD拟议规则制定的预先通知，并开始收集数据，以更好地了解与该化学品及其副产品6PPD醌相关的健康和环境风险。该机构还计划根据《有毒物质控制法》最终确定一项规则，该规则将要求6PPD的制造商和进口商报告任何未发表的健康和安全研究
{"title":"EPA will consider regulating tire compound","authors":"None Krystal Vasquez","doi":"10.1021/cen-10137-polcon3","DOIUrl":"https://doi.org/10.1021/cen-10137-polcon3","url":null,"abstract":"The US Environmental Protection Agency has agreed to hear a petition by the Yurok, Port Gamble S’Klallam, and Puyallup tribes calling for the agency to regulate the use of N -(1,3-dimethylbutyl)- N ’-phenyl- p -phenylenediamine, known as 6PPD, in tires. The compound is linked to mass die-offs of coho salmon , which are central to the cultures, diets, and economies of these three tribes and important to other communities on the West Coast. In a response to the petition , the EPA says that in the coming months it will issue an advance notice of proposed rulemaking for 6PPD and begin gathering data to better understand the health and environmental risks associated with the chemical and a by-product, 6PPD-quinone. The agency also plans to finalize a rule under the Toxic Substances Control Act that will require manufacturers and importers of 6PPD to report any unpublished health and safety studies on","PeriodicalId":9517,"journal":{"name":"C&EN Global Enterprise","volume":"27 26","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136282405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-13DOI: 10.1021/cen-10137-buscon8
None Craig Bettenhausen
The biobased chemicals firm DMC Biotechnologies has opened an 880 m 2 R&D site in Research Triangle, North Carolina. DMC uses custom microbes to ferment a range of nutritional ingredients and other specialty chemicals. The facility will house strain and process development labs, analytical suites, and pilot-scale fermentation lines. DMC already has a lab in Boulder, Colorado, focused on isolating products after fermentation.
{"title":"DMC opens R&D facility in North Carolina","authors":"None Craig Bettenhausen","doi":"10.1021/cen-10137-buscon8","DOIUrl":"https://doi.org/10.1021/cen-10137-buscon8","url":null,"abstract":"The biobased chemicals firm DMC Biotechnologies has opened an 880 m 2 R&D site in Research Triangle, North Carolina. DMC uses custom microbes to ferment a range of nutritional ingredients and other specialty chemicals. The facility will house strain and process development labs, analytical suites, and pilot-scale fermentation lines. DMC already has a lab in Boulder, Colorado, focused on isolating products after fermentation.","PeriodicalId":9517,"journal":{"name":"C&EN Global Enterprise","volume":"28 23","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136282582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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