Advanced Sensor Research最新文献

As people increased emphasis on health problems, various wearable electronic devices are developed for sport-related activity monitoring. However, these reported sensors must be tightly attached on the body to record the photonic, electronic even chemical changes during exercise. Poor user experience hinders the rapid application of wearable sensors. Here, an all-printed perovskite photodetector for achieving non-contact sports motion monitoring is developed. 1D MAPbBr₃ arrays are printed with uniform orientation and strict crystallization via the droplet-manipulation printing strategy. Under the guidance of microarrays on the template, the perovskite-loaded droplet can be self-shaped into the linear confined liquid space for the next crystallization. 1D perovskite photodetectors with high responsivity (R, MAX: 198 A W⁻¹) and detectivity (D^*, MAX: 6.64 × 10¹³ Jones) can be utilized to detect changes in the ambient light intensity under the body during the push-up movement, achieving non-contact real-time monitoring of motions. The average accuracy of printed photodetectors to classify the collected push-up signals reaches 97.40%. This strategy provides a reference for further improving the sensing performance of wearable sensors, which also extends the application of sports monitoring.

Adv. Sensor Res. 2023, 2, 2200060

In the section “Acknowledgments”, we would like to add the sentence “R.B. acknowledges that this project has received funding from the European Union's Horizon 2020 Research and Innovation Programme under the Marie Skłodowska-Curie Grant Agreement No 898571”. This sentence should be added after the sentence “L.B. acknowledges the support provided by the National Science Foundation Graduate Research Fellowship Program under Grant DGE-2038238.”

The error was that there is a missing sentence acknowledging a funding source for the author R.B in the manuscript. The correction involves adding the requested sentence, and acknowledging the funding source for author R.B.

We apologize for this error. This sentence was not added by mistake. Thank you so much for your consideration.

Gold nanorods (AuNRs), 1D rod-shaped nanomaterials, hold a crucial role in sensing applications due to their distinct physicochemical properties, such as high surface area, efficient mass transfer, good biocompatibility, and anisotropic optical and electronic responses. This review outlines the most recent advancements in AuNRs research, offering a comprehensive summary of synthetic strategies. Subsequently, the potential of AuNRs in sensor applications is discussed, and for the first time, an innovative analysis of their application in the sensor field based on the aspect ratio of AuNRs is proposed. These sensing systems are utilized for detecting heavy metal ions, inorganic anions, small biomolecules, protein tumor markers, enzymes, and nucleic acids. Finally, the future research directions and challenges of AuNRs are addressed.

Equipping otherwise passive surfaces with electronic functionality enables advanced interactive robotics, consumer products, sensor skins, and structural health monitoring. Concurrently, the rapidly growing number of electronic devices fuels the search for sustainable materials and processes that aid in reducing electronic waste. Wood is CO₂-neutral, omnipresent in the construction industry, in furniture, musical instruments, or packaging, yet so far, its potential for direct integration with electronics remains largely unexplored. Complications arise as traditional methods of equipping wood with electronics often compromise structural integrity and thus limit applications requiring load-bearing capabilities. Here, seamless fabrication methods that allow the direct enhancement of wooden surfaces with electrically conducting structures, sensors, and microelectronic components based on screen printing of conducting inks or physical vapor deposition of thin metal films in conjunction with laser engraving are presented. Such electronic circuits imperceptibly operate on the surface of structural elements or as parts of decorative wooden furniture. These types of electronic wooden surfaces enable touch-sensing applications, monitoring temperature, or the curing of varnishes without compromising functionality and mechanical stability. This multidisciplinary approach opens up new avenues for the development of smart wooden structures with embedded electronics, revolutionizing the way it is monitored, controlled, and interacted with wood-based constructions.

Precision radiotherapy, such as targeted radioligand therapy, accentuates the precise delivery of radiation to tumor cells while limiting radiation damage to surrounding normal cells. Although recent clinical trial data has shown targeted radioligand therapy to have significant patient survival benefit, it is still unavoidable that the cancer cells will eventually adapt and develop radioresistance. Thus, the study of radiotherapy-induced changes in the tumor microenvironment (TME) is crucial for developing strategies to best overcome radioresistance. To this end, organ-on-chip (OOC) systems with integrative sensors represent cutting-edge pre-clinical models for miniaturized 3D modelling and profiling of the TME. This Review features OOC systems which have demonstrated feasibility for radiation-associated studies, as well as showcased the progress of different OOC systems for profiling core components of the TME. Furthermore, this Review discusses the knowledge gap in cancer-on-chip systems with integrative TME sensors for precision radiotherapy applications. It is anticipated that this Review can kickstart the propagation of new concepts and approaches to drive a new era of miniaturized sensors on OOC systems for precision radiotherapy.

Solid-state nanopore sensors, a type of resistive pulse sensing, achieve optimal signal-to-noise performance with a single nanopore. However, the processes involved in solid-state nanopore fabrication and subsequent measurements frequently lead to the formation of multiple nanopores, posing a challenge for precise detection. To address this issue, here, a novel and expedient technique to verify the presence of a single nanopore on a chip is developed. The methodology includes measuring the nanopore's conductance in solutions of various salt conditions, followed by a comparison of these results against a theoretical conductance model. This comparison is instrumental in distinguishing between single and multiple nanopores. Additionally, the study delves into various factors that influence the conductance curve, such as deviations in pore shape from the standard circle and inconsistencies in pore diameter. This approach significantly enhances the practical application of low-cost nanopore preparation techniques, particularly in scenarios like controlled breakdown nanopore fabrication, where the formation of multiple nanopores is a common concern.

The strongly growing interest in digitalizing society requires simple and reliable strain-sensing concepts. In this work, a highly sensitive stretchable sensor is presented using a straightforward and scalable printing method. The piezoresistive sensor consists of conductive core–shell microspheres embedded in an elastomer. As the elastomer, ethylene vinyl acetate (EVA) is employed as an efficient and cost-effective alternative compared to polydimethylsiloxane (PDMS). EVA allows for a significantly lower percolation threshold and low hysteresis compared with PDMS. Using 35 µm microspheres, a detection limit of 0.01% is achieved. When using 4 µm microspheres, the sensor shows a detection limit of 0.015% and electromechanical robustness against 1000 cycles of 0–1% strain. The stretchable strain sensor is successfully implemented as an impact sensor and a diaphragm expansion monitoring sensor. Fast (20 ms) and high-resolution response as well as mechanical robustness to strain values greater than the linear working range of the sensor are demonstrated. The results of this research indicate the promising potential of employing conductive microspheres embedded in the EVA matrix for fast and precise strain detection applications.

Early intervention in acute myocardial infarction can minimize myocardial damage and improve patient survival. Herein, a low-cost device-free portable immunobiosensing platform for flexible monitoring of immediate myocardial infarction is reported. CuS-Pt nanofragments (CuS-Pt NFs) with high photothermal conversion efficiency (≈26.41%) are synthesized by liquid-phase polarity-mediated synthesis. The CuS NFs are loaded in situ with platinum (Pt) nanoreactors using a solvothermal reduction strategy, which is employed to enhance the efficiency of gas production. The resulting CuS-Pt nanocatalysts are encapsulated within liposomes for signal cascade amplification. Specifically, cardiac troponin I (cTn I), a target biomarker in serum, is captured on pre-modified microtiter plates and formed into a classical sandwich model. The thermo-chemically kinetically enhanced CuS-Pt reactor is released through a one-step chemical treatment and transferred to a closed gas generator. Under the excitation of a near-infrared laser emitter, the internal pressure in the gas generator device increases with time and drives the carbon quantum dot solution in the connected hose. The moving distance shows a correlation with the target concentration. This work provides a new implementation for the development of low-cost, efficient pressure immunosensors without the requirement of a readout device.

Hydraulic fluid power systems are essential for a range of engineering applications such as transportation, heavy industry, and robotics. The scale of the industry is such that hydraulic pumps are estimated to account for 15% of all the energy consumption in the European Union and yet the average efficiency of fluid power systems is only 22%. The digitalization of hydraulic systems offers significant advantages in terms of energy efficiency, performance, reduced maintenance, and automation. However, this requires advances in the integration of smart sensing technologies to provide real-time feedback on the operation and health of hydraulic components. This review details developing trends in hydraulic fluid power research and provides an overview of progress related to the digitalization of these systems and their integration within an Industry 4.0 framework. The fundamentals of relevant sensor technologies and innovative approaches for integrating sensors into hydraulics systems are discussed. Methods to deliver power to the sensors and associated electronics through harvested pressure ripples are also reviewed. An outlook with respect to future directions in this field is given, including an assessment of the potential for exploiting advanced manufacturing technologies, in particular additive manufacturing, to facilitate successful sensor integration into hydraulic fluid power systems.

Lipid droplets (LDs) are dynamic cellular organelles that play an essential role in lipid metabolism and storage. LD dysregulation has been implicated in various diseases. However, investigations into the cellular LD dynamics under disease conditions have been rarely reported, possibly due to the absence of high performing LD imaging agents. Here a novel fluorogenic probe, AM-QTPA, is reported for specific LD imaging. AM-QTPA demonstrates viscosity sensitivity and aggregation-induced emission enhancement characteristics. It is live cell permeable and can specifically light up LDs in cells, with low background noise and superior signals that can be quantified. After validation in cell model with LD accumulation induced by oleic acid treatment, AM-QTPA is applied in a small proof-of-concept number of human fibroblast samples derived from people diagnosed with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), a complex and debilitating disease with unknown cause. The results indicate the presence of larger but fewer LDs in ME/CFS fibroblasts compared to the healthy counterparts, accompanying with frequent LD-mitochondria contacts, suggesting potential upregulation of lipolysis in ME/CFS connective tissue like fibroblasts. Overall, AM-QTPA provides new understanding of the anomalous LD dynamics in disease status, which, potentially, will facilitate in-depth investigation of the pathogenesis of ME/CFS.