首页 > 最新文献

Health Care Science最新文献

英文 中文
Prevention and control measures to further optimize COVID-19 response 进一步优化新冠肺炎应对的防控措施
Pub Date : 2023-01-15 DOI: 10.1002/hcs2.34
Released by the Taskforce for Joint Prevention and Control Mechanism for COVID-19 under the State Council of P.R. China on December 07, 2022

On November 11, 2022, the Chinese government released the Scientific and Targeted Prevention and Control Measures to Optimize COVID-19 Response. Since that time, adjusted measures have been implemented throughout China, leading to major shifts in implementation of the national prevention and control strategy. On the basis of the current situation of the epidemic and the evolving SARS-Cov-2 variants, an additional 10 specifications (referred to as “the 10-point measures”) were officially released on December 7, 2022, in an effort to further optimize the prevention and control measures. The latest adjustments pertain to the specification of: precise delineation of high-risk areas, nucleic acid testing scheme, isolation and health monitoring, restriction and lifting of high-risk areas, medicine supply, vaccination rollout among older people, health status of key populations, social functioning, and campus response.

2022年11月11日,中国政府发布《科学精准防控措施优化新冠肺炎应对》。从那时起,调整后的措施在中国各地实施,导致国家防控战略的实施发生重大转变。在当前疫情和不断演变的严重急性呼吸系统综合征冠状病毒2型变种的基础上,2022年12月7日正式发布了额外的10项规范(简称“10点措施”),以进一步优化防控措施。最新的调整涉及以下方面的规范:高风险地区的精确划定、核酸检测计划、隔离和健康监测、高风险区域的限制和解除、药品供应、老年人疫苗接种、重点人群的健康状况、社会功能和校园应对。
{"title":"Prevention and control measures to further optimize COVID-19 response","authors":"Released by the Taskforce for Joint Prevention and Control Mechanism for COVID-19 under the State Council of P.R. China on December 07, 2022","doi":"10.1002/hcs2.34","DOIUrl":"https://doi.org/10.1002/hcs2.34","url":null,"abstract":"<p>On November 11, 2022, the Chinese government released the Scientific and Targeted Prevention and Control Measures to Optimize COVID-19 Response. Since that time, adjusted measures have been implemented throughout China, leading to major shifts in implementation of the national prevention and control strategy. On the basis of the current situation of the epidemic and the evolving SARS-Cov-2 variants, an additional 10 specifications (referred to as “<b>the 10-point measures</b>”) were officially released on December 7, 2022, in an effort to further optimize the prevention and control measures. The latest adjustments pertain to the specification of: precise delineation of high-risk areas, nucleic acid testing scheme, isolation and health monitoring, restriction and lifting of high-risk areas, medicine supply, vaccination rollout among older people, health status of key populations, social functioning, and campus response.</p>","PeriodicalId":100601,"journal":{"name":"Health Care Science","volume":"2 1","pages":"7-9"},"PeriodicalIF":0.0,"publicationDate":"2023-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/hcs2.34","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50133376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Scientific and targeted prevention and control measures to optimize COVID-19 response 科学、有针对性的防控措施,优化新冠肺炎应对
Pub Date : 2023-01-12 DOI: 10.1002/hcs2.33
Released by the Taskforce for Joint Prevention and Control Mechanism for COVID-19 under the State Council and the National Health Commission of P.R. China on November 11, 2022

Since the outbreak of the COVID-19 pandemic, under the strong leadership of the Central Committee of the Communist Party of China and President Xi Jinping, China has made firm decisions to prioritize people's lives and health. Efforts have been made to avoid foreign imported infection and domestic rebound of COVID-19 cases; the “dynamic zero COVID” policy has been executed without wavering; and the prevention and control measures have been optimized and improved in response to changing circumstances, actively responding to the impact caused by multiple waves of COVID-19 surge globally. China has made extraordinary efforts to safeguard people's lives and health. Meanwhile, prevention and control measures were timely updated to coordinate with economic and social development. On November 10, the Standing Committee of the Central Political Bureau held a meeting to discuss the latest situation of the COVID-19 pandemic in China. Twenty measures (referred to as “the 20-point measures“) were officially announced to further optimize the COVID-19 response. The latest prevention and control measures involve the requirements and guidance for isolation at home, high-risk area delineation, nucleic acid testing, international inbound flights and travelers, vaccination rollout, medical resource preparedness, and protection for special places and vulnerable population.

努力避免境外输入性感染和新冠肺炎病例在国内反弹;“动态清零”政策执行得毫不动摇;根据形势变化,优化和完善防控措施,积极应对全球多波新冠肺炎疫情造成的影响。中国为保障人民生命健康作出了非凡努力。同时,及时更新防控措施,以配合经济社会发展。11月10日,中央政治局常务委员会召开会议,讨论新冠肺炎疫情在中国的最新形势。二十条措施(简称“二十条措施”)官方宣布进一步优化新冠肺炎应对措施。最新的防控措施涉及居家隔离、高风险地区划定、核酸检测、国际入境航班和旅行者、疫苗接种、医疗资源准备以及特殊场所和弱势人群保护的要求和指导。
{"title":"Scientific and targeted prevention and control measures to optimize COVID-19 response","authors":"Released by the Taskforce for Joint Prevention and Control Mechanism for COVID-19 under the State Council and the National Health Commission of P.R. China on November 11, 2022","doi":"10.1002/hcs2.33","DOIUrl":"https://doi.org/10.1002/hcs2.33","url":null,"abstract":"<p>Since the outbreak of the COVID-19 pandemic, under the strong leadership of the Central Committee of the Communist Party of China and President Xi Jinping, China has made firm decisions to prioritize people's lives and health. Efforts have been made to avoid foreign imported infection and domestic rebound of COVID-19 cases; the “dynamic zero COVID” policy has been executed without wavering; and the prevention and control measures have been optimized and improved in response to changing circumstances, actively responding to the impact caused by multiple waves of COVID-19 surge globally. China has made extraordinary efforts to safeguard people's lives and health. Meanwhile, prevention and control measures were timely updated to coordinate with economic and social development. On November 10, the Standing Committee of the Central Political Bureau held a meeting to discuss the latest situation of the COVID-19 pandemic in China. Twenty measures (referred to as “<b>the 20-point measures</b>“) were officially announced to further optimize the COVID-19 response. The latest prevention and control measures involve the requirements and guidance for isolation at home, high-risk area delineation, nucleic acid testing, international inbound flights and travelers, vaccination rollout, medical resource preparedness, and protection for special places and vulnerable population.</p>","PeriodicalId":100601,"journal":{"name":"Health Care Science","volume":"2 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2023-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/hcs2.33","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50129697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Socioeconomic and epidemiological milieu of maternal death due to eclampsia in West Bengal, India: A mixed methods study 印度西孟加拉邦子痫孕产妇死亡的社会经济和流行病学环境:一项混合方法研究
Pub Date : 2022-12-21 DOI: 10.1002/hcs2.28
Md Illias Kanchan Sk

Background

West Bengal is experiencing an unanticipated risk of eclampsia among pregnant women and it persists as the leading cause of maternal mortality. This study aimed to investigate the predictors for maternal deaths due to eclampsia in West Bengal.

Methods

The study adopted retrospective mixed methods covering facility and community-based maternal death review approaches. Facility-based data were used for 317 deceased cases wherein the community-based review approach was used in 40 cases. An in-depth interview was also performed among 12 caregivers.

Results

One-third of maternal deaths occurred due to eclampsia, and this accounted for the leading cause of maternal deaths in West Bengal. A younger age, a primigravida or nulliparous status, absence of antenatal care (ANC), and residence in rural areas appeared to have the highest risk of developing eclampsia. The majority of pregnant women had an irregular antenatal check-up history, particularly during the second trimester of pregnancy. The rate of eclampsia-related maternal death was higher in women residing more than 49 km from the studied hospitals. Most of the deceased women were referred to three or more hospitals before their death. Gravidity, the number of ANC visits, the mode of delivery, and delays at different levels were significant confounders of death due to eclampsia. The risk of death due to eclampsia was two times higher among women without ANC and those who had a cesarean section than that in their counterparts.

Conclusions

Women in West Bengal have a high risk of preeclampsia and eclampsia resulting in maternal mortality and morbidity. Gravidity, the number of ANC visits, the mode of delivery, and delays in recognition of eclampsia contribute to the risk of maternal deaths. The establishment of separate eclampsia units, enhanced screening, and preventive and treatment procedures may optimize managing eclampsia.

背景西孟加拉邦孕妇正经历着一种意想不到的子痫风险,它一直是孕产妇死亡的主要原因。本研究旨在调查西孟加拉邦孕产妇因子痫死亡的预测因素。方法采用回顾性混合方法,包括设施和社区孕产妇死亡回顾方法。基于设施的数据用于317例死亡病例,其中基于社区的审查方法用于40例。还对12名护理人员进行了深入访谈。结果三分之一的孕产妇死亡发生在子痫,子痫是西孟加拉邦孕产妇死亡的主要原因。年龄较小、初产妇或未产妇、缺乏产前护理(ANC)以及居住在农村地区似乎是患子痫的最高风险人群。大多数孕妇有不定期的产前检查史,尤其是在妊娠中期。居住在49岁以上的妇女与子痫相关的孕产妇死亡率更高 距离研究医院公里。大多数已故妇女在去世前都被转诊到三家或三家以上的医院。妊娠、ANC就诊次数、分娩方式和不同程度的延迟是子痫死亡的重要混杂因素。没有ANC的女性和剖宫产的女性因子痫死亡的风险是同行的两倍。结论西孟加拉邦妇女有很高的先兆子痫和子痫风险,导致孕产妇死亡率和发病率。妊娠、ANC就诊次数、分娩方式和子痫识别延迟都会增加产妇死亡的风险。建立独立的子痫病房、加强筛查以及预防和治疗程序可能会优化子痫的管理。
{"title":"Socioeconomic and epidemiological milieu of maternal death due to eclampsia in West Bengal, India: A mixed methods study","authors":"Md Illias Kanchan Sk","doi":"10.1002/hcs2.28","DOIUrl":"https://doi.org/10.1002/hcs2.28","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>West Bengal is experiencing an unanticipated risk of eclampsia among pregnant women and it persists as the leading cause of maternal mortality. This study aimed to investigate the predictors for maternal deaths due to eclampsia in West Bengal.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The study adopted retrospective mixed methods covering facility and community-based maternal death review approaches. Facility-based data were used for 317 deceased cases wherein the community-based review approach was used in 40 cases. An in-depth interview was also performed among 12 caregivers.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>One-third of maternal deaths occurred due to eclampsia, and this accounted for the leading cause of maternal deaths in West Bengal. A younger age, a primigravida or nulliparous status, absence of antenatal care (ANC), and residence in rural areas appeared to have the highest risk of developing eclampsia. The majority of pregnant women had an irregular antenatal check-up history, particularly during the second trimester of pregnancy. The rate of eclampsia-related maternal death was higher in women residing more than 49 km from the studied hospitals. Most of the deceased women were referred to three or more hospitals before their death. Gravidity, the number of ANC visits, the mode of delivery, and delays at different levels were significant confounders of death due to eclampsia. The risk of death due to eclampsia was two times higher among women without ANC and those who had a cesarean section than that in their counterparts.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Women in West Bengal have a high risk of preeclampsia and eclampsia resulting in maternal mortality and morbidity. Gravidity, the number of ANC visits, the mode of delivery, and delays in recognition of eclampsia contribute to the risk of maternal deaths. The establishment of separate eclampsia units, enhanced screening, and preventive and treatment procedures may optimize managing eclampsia.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100601,"journal":{"name":"Health Care Science","volume":"2 1","pages":"45-59"},"PeriodicalIF":0.0,"publicationDate":"2022-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/hcs2.28","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50140002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigation of pelvic symmetry: A systematic analysis using computer aided design software 骨盆对称性研究:计算机辅助设计软件的系统分析
Pub Date : 2022-11-08 DOI: 10.1002/hcs2.25
Qiubao Zheng, Kangshuai Xu, Xiaorui Zhan, Fuming Huang, Liping Wang, Sheqiang Chen, Jiacheng Li, Cheng Yang, Yuhui Chen, Shicai Fan

Objectives

This study aimed to investigate the symmetry of the Chinese pelvis.

Methods

Computed tomography scan images of each of 50 Chinese pelvises were converted to 3D models and the left sides of the pelvises were reflected on Mimics software. Then, the reflected left side model was aligned with the right side using the closest point algorithm function of Geomagic software to perform symmetry analysis. The volume and surface area of either side of the pelvises were also calculated. The mean standard deviation (SD), the mean percentage of permissible deviations within the ±2 mm range, the percentage differences in volume and surface area were measured to compare pelvic symmetry. In addition, the distribution of pelvic bilateral symmetry associated with both age and sex were compared.

Results

The mean SD was 1.15 ± 0.16 mm and the mean percentage of permissible deviations was 90.82% ± 4.67%. The deviation color maps showed that the specific areas of asymmetry were primarily localized to major muscle or ligament attachment sites and the sacroiliac joint surfaces. There was no significant difference between the bilateral sides of the pelvis in either volume or surface area. Additionally, no difference in any indexes was exhibited in relation to sex and age distribution.

Conclusion

Our results demonstrated that the pelvis has high bilateral symmetry, which confirmed the potential of using contralateral pelvic models to create fully patient-specific and custom-made pelvic implants applicable for the treatment of fracture and bony destruction.

目的探讨中国人骨盆的对称性。方法将50个中国人骨盆的计算机断层扫描图像转换为三维模型,并在Mimics软件上反映骨盆左侧。然后,使用Geomagic软件的最近点算法函数将反射的左侧模型与右侧模型对齐,以进行对称性分析。还计算了骨盆两侧的体积和表面积。平均标准偏差(SD),±2范围内允许偏差的平均百分比 mm范围内,测量体积和表面积的百分比差异以比较骨盆对称性。此外,还比较了与年龄和性别相关的骨盆双侧对称性的分布。结果平均SD为1.15 ± 0.16 mm,允许偏差的平均百分比为90.82% ± 偏差彩色图显示,不对称的特定区域主要局限于主要肌肉或韧带附着部位和骶髂关节表面。骨盆两侧的体积或表面积均无显著差异。此外,性别和年龄分布在任何指标上都没有差异。结论我们的研究结果表明,骨盆具有高度的双侧对称性,这证实了使用对侧骨盆模型来创建适用于骨折和骨破坏治疗的完全针对患者的定制骨盆植入物的潜力。
{"title":"Investigation of pelvic symmetry: A systematic analysis using computer aided design software","authors":"Qiubao Zheng,&nbsp;Kangshuai Xu,&nbsp;Xiaorui Zhan,&nbsp;Fuming Huang,&nbsp;Liping Wang,&nbsp;Sheqiang Chen,&nbsp;Jiacheng Li,&nbsp;Cheng Yang,&nbsp;Yuhui Chen,&nbsp;Shicai Fan","doi":"10.1002/hcs2.25","DOIUrl":"https://doi.org/10.1002/hcs2.25","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This study aimed to investigate the symmetry of the Chinese pelvis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Computed tomography scan images of each of 50 Chinese pelvises were converted to 3D models and the left sides of the pelvises were reflected on Mimics software. Then, the reflected left side model was aligned with the right side using the closest point algorithm function of Geomagic software to perform symmetry analysis. The volume and surface area of either side of the pelvises were also calculated. The mean standard deviation (SD), the mean percentage of permissible deviations within the ±2 mm range, the percentage differences in volume and surface area were measured to compare pelvic symmetry. In addition, the distribution of pelvic bilateral symmetry associated with both age and sex were compared.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The mean SD was 1.15 ± 0.16 mm and the mean percentage of permissible deviations was 90.82% ± 4.67%. The deviation color maps showed that the specific areas of asymmetry were primarily localized to major muscle or ligament attachment sites and the sacroiliac joint surfaces. There was no significant difference between the bilateral sides of the pelvis in either volume or surface area. Additionally, no difference in any indexes was exhibited in relation to sex and age distribution.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Our results demonstrated that the pelvis has high bilateral symmetry, which confirmed the potential of using contralateral pelvic models to create fully patient-specific and custom-made pelvic implants applicable for the treatment of fracture and bony destruction.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100601,"journal":{"name":"Health Care Science","volume":"2 1","pages":"36-44"},"PeriodicalIF":0.0,"publicationDate":"2022-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/hcs2.25","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50125196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transfer or tailor? Implementing a technology-supported intervention for noncommunicable diseases across contexts 调动还是裁缝?跨环境实施技术支持的非传染性疾病干预措施
Pub Date : 2022-11-07 DOI: 10.1002/hcs2.26
Thomas Gadsden, Anushka Patel, Devarsetty Praveen, Anna Palagyi

In May 2022, the 75th World Health Assembly recognized the need to accelerate national responses to the growing burden of noncommunicable diseases (NCDs) to achieve the goals of the Global Action Plan (GAP) for the Prevention and Control of NCDs. To facilitate this, an implementation roadmap was adopted that urges countries to prioritize the implementation of NCD interventions that are most appropriate to their specific local and regional context. The roadmap will act as an overarching guide for countries to tackle NCDs via three approaches: (i) Accelerate national responses based on local NCD epidemiology, risk factors and identified barriers and enablers; (ii) Prioritize and scale up the implementation of most impactful and feasible interventions according to the local context; and (iii) Ensure timely, reliable and sustained national data on NCD risk factors and mortality for data driven actions and to strengthen accountability [1].

With the end date of 2030 for the NCD-GAP fast approaching, the adaptation of proven interventions is likely the most efficient and effective means by which countries can make inroads into NCD control [2]. While investment in continued research and innovation to support such adaptation processes is vital, prior knowledge and experience with the implementation of NCD interventions highlight a series of common principles that—if leveraged—can provide programs for NCD prevention and management with the strongest chance of success. In this perspective piece we share such key principles emerging from our own experience implementing a multifaceted NCD management intervention—SMARThealth (Systematic Medical Appraisal Referral and Treatment)—across different country contexts.

SMARThealth is a technology-supported, multifaceted primary health care intervention aimed at improving the provision of guideline-based assessment and prevention or management of common NCDs. A central common component of the SMARThealth intervention is a clinical decision support system (CDSS) with context-defined variations in disease focus and approach to health system integration, including workforce strategy [3] (Figure 1).

The intervention was first piloted in Australia as a CDSS embedded in existing patient management information systems and delivered by general practitioners (GPs) [4]. Encouraged by positive outcomes (e.g., improved cardiovascular risk factor screening, namely blood pressure [BP] recording and up-titration of cardiovascular preventive drugs), the CDSS was adapted to the Indian primary health care setting by expanding the platform to include a mobile application that can be used by frontline health workers within rural communities to support early identification, referral, and management for cardiovascular disease. Though the platform was found to be acceptable by the community and health professionals across test sites in rural India,

2022年5月,第75届世界卫生大会认识到,有必要加快国家应对日益严重的非传染性疾病负担,以实现《预防和控制非传染性疾病全球行动计划》的目标。为了促进这一点,通过了一项实施路线图,敦促各国优先实施最适合其特定地方和区域背景的非传染性疾病干预措施。路线图将作为各国通过三种方法应对非传染性疾病的总体指南:(一)根据当地非传染性疾病流行病学、风险因素以及已确定的障碍和促成因素,加快国家应对措施;二根据当地情况,优先考虑并扩大实施最具影响力和可行性的干预措施;以及(iii)确保及时、可靠和持续的关于非传染性疾病风险因素和死亡率的国家数据,用于数据驱动的行动,并加强问责制[1]。随着2030年非传染性疾病全球行动计划的结束日期即将到来,采用经验证的干预措施可能是各国控制非传染性疾病的最有效和最有效的手段[2]。尽管投资于持续的研究和创新以支持这种适应过程至关重要,但先前实施非传染性疾病干预措施的知识和经验突出了一系列共同原则,如果加以利用,这些原则可以为非传染性疾病预防和管理计划提供最有可能成功的机会。在这篇观点文章中,我们分享了我们在不同国家实施多方面非传染性疾病管理干预措施——SMARThealth(系统医疗评估转诊和治疗)的经验中得出的这些关键原则。SMARThealth是一种技术支持的多方面初级卫生保健干预措施,旨在改善对常见非传染性疾病的基于指南的评估和预防或管理。SMARThealth干预的中心共同组成部分是临床决策支持系统(CDSS),该系统在疾病焦点和卫生系统集成方法方面具有上下文定义的变化,包括劳动力战略[3](图1)。该干预措施最初在澳大利亚进行试点,作为嵌入现有患者管理信息系统的CDSS,由全科医生提供[4]。在积极结果的鼓励下(例如,改进了心血管危险因素筛查,即血压[BP]记录和心血管预防药物的上调),CDSS通过扩展平台以包括移动应用程序来适应印度初级卫生保健环境,农村社区的一线卫生工作者可以使用该应用程序来支持早期识别,心血管疾病的治疗、转诊和管理。尽管该平台被发现为印度农村测试点的社区和卫生专业人员所接受,但集群随机试验中没有明确的临床益处证据(例如,在实现血压目标或接受降压药物方面没有差异)[5,6]。相反,随后在印度尼西亚农村类似初级卫生保健环境中进行的一项试验是非常积极的(例如,在接受干预的人群中,使用更高的降压药物和更低的血压水平),导致当地政府当局采用干预措施扩大规模[7]。为了进一步评估实施结果的差异,SMART健康干预的试点目前正在中国和泰国进行[8]。背景,卫生系统干预,非传染性疾病Thomas Gadsden:写作——初稿(牵头);写作——审查和编辑(领导)。阿努什卡·帕特尔:概念化(平等);项目管理(牵头);写作——复习和编辑(同等)。Devarsetty Praveen:写作——审查和编辑(支持)。安娜·帕拉吉:概念化(平等);书面——原始草稿(同等);写作-审查和编辑(平等)。作者声明没有利益冲突。无声明。没有一个
{"title":"Transfer or tailor? Implementing a technology-supported intervention for noncommunicable diseases across contexts","authors":"Thomas Gadsden,&nbsp;Anushka Patel,&nbsp;Devarsetty Praveen,&nbsp;Anna Palagyi","doi":"10.1002/hcs2.26","DOIUrl":"https://doi.org/10.1002/hcs2.26","url":null,"abstract":"<p>In May 2022, the 75th World Health Assembly recognized the need to accelerate national responses to the growing burden of noncommunicable diseases (NCDs) to achieve the goals of the Global Action Plan (GAP) for the Prevention and Control of NCDs. To facilitate this, an implementation roadmap was adopted that urges countries to prioritize the implementation of NCD interventions that are most appropriate to their specific local and regional context. The roadmap will act as an overarching guide for countries to tackle NCDs via three approaches: (i) Accelerate national responses based on local NCD epidemiology, risk factors and identified barriers and enablers; (ii) Prioritize and scale up the implementation of most impactful and feasible interventions according to the local context; and (iii) Ensure timely, reliable and sustained national data on NCD risk factors and mortality for data driven actions and to strengthen accountability [<span>1</span>].</p><p>With the end date of 2030 for the NCD-GAP fast approaching, the adaptation of proven interventions is likely the most efficient and effective means by which countries can make inroads into NCD control [<span>2</span>]. While investment in continued research and innovation to support such adaptation processes is vital, prior knowledge and experience with the implementation of NCD interventions highlight a series of common principles that—if leveraged—can provide programs for NCD prevention and management with the strongest chance of success. In this perspective piece we share such key principles emerging from our own experience implementing a multifaceted NCD management intervention—SMART<i>health</i> (Systematic Medical Appraisal Referral and Treatment)—across different country contexts.</p><p>SMART<i>health</i> is a technology-supported, multifaceted primary health care intervention aimed at improving the provision of guideline-based assessment and prevention or management of common NCDs. A central common component of the SMART<i>health</i> intervention is a clinical decision support system (CDSS) with context-defined variations in disease focus and approach to health system integration, including workforce strategy [<span>3</span>] (Figure 1).</p><p>The intervention was first piloted in Australia as a CDSS embedded in existing patient management information systems and delivered by general practitioners (GPs) [<span>4</span>]. Encouraged by positive outcomes (e.g., improved cardiovascular risk factor screening, namely blood pressure [BP] recording and up-titration of cardiovascular preventive drugs), the CDSS was adapted to the Indian primary health care setting by expanding the platform to include a mobile application that can be used by frontline health workers within rural communities to support early identification, referral, and management for cardiovascular disease. Though the platform was found to be acceptable by the community and health professionals across test sites in rural India,","PeriodicalId":100601,"journal":{"name":"Health Care Science","volume":"2 1","pages":"75-78"},"PeriodicalIF":0.0,"publicationDate":"2022-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/hcs2.26","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50134779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A systematic review on the cost-effectiveness of the computer-assisted orthopedic system 计算机辅助骨科系统成本效益的系统综述
Pub Date : 2022-11-02 DOI: 10.1002/hcs2.23
Hua Li, Tengfeng Zhuang, Wenrui Wu, Wenyi Gan, Chongjie Wu, Sijun Peng, Songwei Huan, Ning Liu

Computer-assisted orthopedic system (CAOS) is rapidly gaining popularity in the field of precision medicine. However, the cost-effectiveness of CAOS has not been well clarified. We performed this review to summarize and assess the cost-effectiveness analyses (CEAs) with regard to CAOS. Publications on CEA in CAOS have been searched in PubMed and CEA Registry up to May 31, 2022. The Quality of Health Economic Studies (QHES) instrument was used to estimate the quality of studies. Relationships between qualities and potential factors were also examined. There were 15 eligible studies in the present review. Twelve studies evaluated CAOS joint arthroplasties and found that CAOS joint arthroplasties were cost-effective compared to manual methods. Three studies focused on spinal surgery, two of which analyzed the cost-effectiveness of CAOS for patients after spinal fusion, with conflicting results. One study demonstrated that CAOS was cost-effective in spinal pedicle screw insertion. The mean QHES score of CEAs included was 86.1. The potential factors had no significant relationship with the quality of studies. Based on available studies, our review reflected that CAOS was cost-effective in the field of joint arthroplasty. While in spinal surgery, the answer was unclear. Current CEAs represent high qualities, and more CEAs are required in the different disciplines of orthopedics where CAOS is employed.

计算机辅助骨科系统(CAOS)在精准医学领域正迅速普及。然而,CAOS的成本效益尚未得到很好的澄清。我们进行了这篇综述,以总结和评估关于CAOS的成本效益分析(cea)。截至2022年5月31日,在PubMed和CEA Registry中检索了CAOS中CEA的出版物。使用卫生经济研究质量(QHES)工具来评估研究的质量。同时还考察了质量与潜在因素之间的关系。在本综述中有15项符合条件的研究。12项研究评估了CAOS关节置换术,发现与手工方法相比,CAOS关节置换术具有成本效益。三项研究聚焦脊柱手术,其中两项研究分析了脊柱融合术后患者CAOS的成本-效果,结果相互矛盾。一项研究表明,CAOS在椎弓根螺钉置入中具有成本效益。入选cea的平均QHES评分为86.1分。潜在因素与研究质量无显著关系。基于现有的研究,我们的综述反映CAOS在关节置换术领域具有成本效益。在脊柱外科手术中,答案还不清楚。目前的cea代表了高质量,在使用CAOS的骨科不同学科中需要更多的cea。
{"title":"A systematic review on the cost-effectiveness of the computer-assisted orthopedic system","authors":"Hua Li,&nbsp;Tengfeng Zhuang,&nbsp;Wenrui Wu,&nbsp;Wenyi Gan,&nbsp;Chongjie Wu,&nbsp;Sijun Peng,&nbsp;Songwei Huan,&nbsp;Ning Liu","doi":"10.1002/hcs2.23","DOIUrl":"10.1002/hcs2.23","url":null,"abstract":"<p>Computer-assisted orthopedic system (CAOS) is rapidly gaining popularity in the field of precision medicine. However, the cost-effectiveness of CAOS has not been well clarified. We performed this review to summarize and assess the cost-effectiveness analyses (CEAs) with regard to CAOS. Publications on CEA in CAOS have been searched in PubMed and CEA Registry up to May 31, 2022. The Quality of Health Economic Studies (QHES) instrument was used to estimate the quality of studies. Relationships between qualities and potential factors were also examined. There were 15 eligible studies in the present review. Twelve studies evaluated CAOS joint arthroplasties and found that CAOS joint arthroplasties were cost-effective compared to manual methods. Three studies focused on spinal surgery, two of which analyzed the cost-effectiveness of CAOS for patients after spinal fusion, with conflicting results. One study demonstrated that CAOS was cost-effective in spinal pedicle screw insertion. The mean QHES score of CEAs included was 86.1. The potential factors had no significant relationship with the quality of studies. Based on available studies, our review reflected that CAOS was cost-effective in the field of joint arthroplasty. While in spinal surgery, the answer was unclear. Current CEAs represent high qualities, and more CEAs are required in the different disciplines of orthopedics where CAOS is employed.</p>","PeriodicalId":100601,"journal":{"name":"Health Care Science","volume":"1 3","pages":"173-185"},"PeriodicalIF":0.0,"publicationDate":"2022-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/hcs2.23","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91224740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The development and impact of adopting electronic health records in the United States: A brief overview and implications for nursing education 在美国采用电子健康记录的发展和影响:简要概述和对护理教育的影响
Pub Date : 2022-11-01 DOI: 10.1002/hcs2.21
Song Ge, Yuting Song, Jiale Hu, Xianping Tang, Junxin Li, Linda Dune

At present, health-care systems in the United States face enormous challenges in providing quality care, characterized by safe, effective, efficient, patient-centered, timely, and equitable care while containing health-care costs [12]. To understand and address patients' increasingly complicated health-care needs, we need safe access to quality information that is characterized by integrity, reliability, and accuracy [3], and establish mutually beneficial relationships among a multidisciplinary team of professionals [4]. Traditional paper-based clinical workflow produces many issues such as illegible handwriting, inconvenient access, the possibility of computational prescribing errors, inadequate patient hand-offs, and drug administration errors. These problems can lead to medical errors, omissions, and duplications and, ultimately, poor patient outcomes and compromised quality of care [2].

Electronic health records (EHR) is a major achievement in the health information technology [5]. It is deemed a promising solution to improve the interoperability of patients' information across health-care settings and achieve a more cost-effective, safer, and higher quality of care [36]. Electronic medical records (EMR) is a different concept from EHR; thus, the two terms cannot be used interchangeably. The EMR is the official record produced by hospitals and other ambulatory settings that serves as the EHR's data source. EMR is a prerequisite for EHR [7]. EHR refers to systematic documentation of patients' health status and health care in a secured digital format [8]. It indicates that patients' health information can not only be stored but also be transmitted and accessed by authorized interdisciplinary professionals across health-care settings in patients' health-care continuum. In addition, authorized non-health-care professionals, including insurers, the government, and researchers can also have access to patients' health information as well.

With EHR, patients can have greater autonomy over their care, and clinicians may better understand patients' medical history and coordinate care with other interdisciplinary professionals with fewer barriers [2]. EHR can also provide data for a variety of other purposes such as providing data for research, population-based interventions, and reporting quality-related measures [9]. Thus, this technological innovation benefits not only patients but also healthcare providers, administrative officers, researchers, and professionals from a variety of disciplines [10].

The adoption of EHR in the United States started early and was accelerated by laws and regulations. In 2004, US President George W. Bush proposed a plan that most Americans would have EHR by 2014. He stated that computerizing health records could help clinicians avo

目前,美国的医疗保健系统在提供安全、有效、高效、以患者为中心、及时和公平的医疗服务同时控制医疗成本方面面临着巨大的挑战[1,2]。为了理解和解决患者日益复杂的保健需求,我们需要安全获取以完整性、可靠性和准确性为特征的高质量信息[b],并在多学科专业人员团队[b]之间建立互利关系[b]。传统的纸质临床工作流程会产生许多问题,如字迹难以辨认、访问不便、计算处方错误的可能性、患者交接不足和药物管理错误。这些问题可能导致医疗差错、遗漏和重复,并最终导致患者预后不良和护理质量下降。电子病历(EHR)是卫生信息技术领域的一项重大成就。它被认为是一种很有前途的解决方案,可以改善医疗保健机构中患者信息的互操作性,并实现更具成本效益、更安全、更高质量的护理[3,6]。电子病历(EMR)是一个不同于EHR的概念;因此,这两个术语不能互换使用。电子病历是由医院和其他门诊机构制作的官方记录,作为电子病历的数据源。电子病历是电子病历[7]的先决条件。电子健康档案是指以安全的数字格式系统地记录患者的健康状况和医疗保健。这表明,患者的健康信息不仅可以存储,而且还可以由经授权的跨学科专业人员在患者保健连续体的各个保健机构中传输和访问。此外,获得授权的非保健专业人员,包括保险公司、政府和研究人员也可以访问患者的健康信息。有了电子健康档案,患者可以对自己的护理有更大的自主权,临床医生可以更好地了解患者的病史,并与其他跨学科专业人员协调护理,减少障碍。电子病历还可以为各种其他目的提供数据,例如为研究、基于人群的干预措施和报告质量相关措施提供数据。因此,这项技术创新不仅有利于患者,也有利于医疗保健提供者、行政官员、研究人员和来自各种学科的专业人员。在美国,电子病历的采用起步较早,并在法律法规的推动下得到了加速。2004年,美国总统乔治·w·布什提出了一项计划,到2014年,大多数美国人将拥有电子病历。他说,计算机化的健康记录可以帮助临床医生避免危险的医疗错误,降低成本,并改善病人的护理。后来,奥巴马总统通过提出《2009年美国复苏与再投资法案》继续了这一努力。该政策包括《卫生信息技术促进经济和临床健康(HITECH)法案》,该法案利用医疗保险和医疗补助为卫生组织和提供者在特定时间框架内有意义地采用电子病历提供明确的报销和惩罚激励[10,13]。在启动这项法案时,联邦政府承诺提供前所未有的资源,以支持采用电子健康档案b[10]。HITECH法案可以被认为是在2019冠状病毒病大流行之前鼓励美国采用电子病历的“最重要的推动力”。值得注意的是,并非所有电子病历都有资格报销。HITECH法案规定,医疗保健提供者和组织必须实施《电子病历》的所有核心目标,然后在头两年完成的十个额外目标中选出五个才有资格获得报销。支持更好的医疗保健的基本任务被包括在HITECH法案定义的关键目标中,包括数据输入和许多基于软件的临床决策支持系统(DSS)[10]。可选目标使提供者有机会根据自己的情况做出选择。尽管技术和标准在不断变化,并且仍然存在接受障碍,但美国的许多医疗保健公司在10多年后实施了电子健康档案。[15]。2001年,只有18%的医生使用电子病历,而2016年这一比例超过80%。此外,根据医疗保健信息和管理系统协会(HIMSS) 2015年分析报告,1313家美国医院已经全面实施了医生文档、强大的临床DSS和医疗成像电子访问(第6阶段)b[17](图1)。自2020年以来发生的2019冠状病毒病(COVID-19)大流行对美国采用EHR产生了前所未有的影响。 重要的概念应该包括在课程中,例如电子病历的发展,它对卫生保健系统的影响,在各种实践环境中有效和安全的技术和信息系统的例子,以及如何保护患者的信息。此外,研究人员还发现,模拟电子病历课程是一种有效且引人入胜的方法,可以教授学生电子病历技能和组织图表,从而实现安全、有效和高质量的患者护理bb0。在模拟的电子病历课程中,学生们使用电子病历培训平台起草医嘱和处方,制定循证护理计划,并在查看了患有慢性疾病和护理不良的复杂患者的虚拟病历后,对他们的工作进行小组审查。在其卫生保健机构严格选择适当的电子病历系统并提供相关支持后,护士应该有能力在工作场所使用电子病历。作为医疗保健的前沿,护士有很大的机会参与这场重大的革命。护士可以在安装前阶段帮助机构选择最合适的系统,利用其专业知识调整系统以适应其机构的需要,鼓励和培训其同事采用系统,并协助其机构评估系统的质量、采用情况和影响。最终,在每个人的努力下,该系统将为包括护士在内的所有医疗保健专业人员提供更好的工作流程和护理结果,如果与该机构整合良好的话。宋歌:概念化(平等);调查(平等);方法(平等)。宋玉婷:概念化(平等);资源(平等)。胡家乐:资源(相等);软件(平等);监督(平等)。汤咸平:调查(同等);软件(平等);监督(平等)。李俊欣:概念化(平等);数据管理(相等);形式分析(相等);写作-原稿(同等);写作-回顾&;编辑(平等)。Linda Dune:形式分析(相等);资金获取(相等)。作者声明无利益冲突。不适用。不适用。
{"title":"The development and impact of adopting electronic health records in the United States: A brief overview and implications for nursing education","authors":"Song Ge,&nbsp;Yuting Song,&nbsp;Jiale Hu,&nbsp;Xianping Tang,&nbsp;Junxin Li,&nbsp;Linda Dune","doi":"10.1002/hcs2.21","DOIUrl":"10.1002/hcs2.21","url":null,"abstract":"<p>At present, health-care systems in the United States face enormous challenges in providing quality care, characterized by safe, effective, efficient, patient-centered, timely, and equitable care while containing health-care costs [<span>1</span>, <span>2</span>]. To understand and address patients' increasingly complicated health-care needs, we need safe access to quality information that is characterized by integrity, reliability, and accuracy [<span>3</span>], and establish mutually beneficial relationships among a multidisciplinary team of professionals [<span>4</span>]. Traditional paper-based clinical workflow produces many issues such as illegible handwriting, inconvenient access, the possibility of computational prescribing errors, inadequate patient hand-offs, and drug administration errors. These problems can lead to medical errors, omissions, and duplications and, ultimately, poor patient outcomes and compromised quality of care [<span>2</span>].</p><p>Electronic health records (EHR) is a major achievement in the health information technology [<span>5</span>]. It is deemed a promising solution to improve the interoperability of patients' information across health-care settings and achieve a more cost-effective, safer, and higher quality of care [<span>3</span>, <span>6</span>]. Electronic medical records (EMR) is a different concept from EHR; thus, the two terms cannot be used interchangeably. The EMR is the official record produced by hospitals and other ambulatory settings that serves as the EHR's data source. EMR is a prerequisite for EHR [<span>7</span>]. EHR refers to systematic documentation of patients' health status and health care in a secured digital format [<span>8</span>]. It indicates that patients' health information can not only be stored but also be transmitted and accessed by authorized interdisciplinary professionals across health-care settings in patients' health-care continuum. In addition, authorized non-health-care professionals, including insurers, the government, and researchers can also have access to patients' health information as well.</p><p>With EHR, patients can have greater autonomy over their care, and clinicians may better understand patients' medical history and coordinate care with other interdisciplinary professionals with fewer barriers [<span>2</span>]. EHR can also provide data for a variety of other purposes such as providing data for research, population-based interventions, and reporting quality-related measures [<span>9</span>]. Thus, this technological innovation benefits not only patients but also healthcare providers, administrative officers, researchers, and professionals from a variety of disciplines [<span>10</span>].</p><p>The adoption of EHR in the United States started early and was accelerated by laws and regulations. In 2004, US President George W. Bush proposed a plan that most Americans would have EHR by 2014. He stated that computerizing health records could help clinicians avo","PeriodicalId":100601,"journal":{"name":"Health Care Science","volume":"1 3","pages":"186-192"},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/hcs2.21","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79264400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Monkey pox: Rethinking COVID-19 to project future strategies against emerging and evolving pathogens 猴痘:重新思考COVID-19以预测未来应对新出现和不断演变的病原体的战略
Pub Date : 2022-10-12 DOI: 10.1002/hcs2.20
Emmanuel Lamptey, Stanley Yaidoo, Ernestina Asiedua, Evans Osei Boakye, Moses tia Banoya, Ephraim Kumi Senkyire

COVID-19 Monkey pox, days like these need planning

COVID-19猴痘,像这样的日子需要规划
{"title":"Monkey pox: Rethinking COVID-19 to project future strategies against emerging and evolving pathogens","authors":"Emmanuel Lamptey,&nbsp;Stanley Yaidoo,&nbsp;Ernestina Asiedua,&nbsp;Evans Osei Boakye,&nbsp;Moses tia Banoya,&nbsp;Ephraim Kumi Senkyire","doi":"10.1002/hcs2.20","DOIUrl":"10.1002/hcs2.20","url":null,"abstract":"<p>COVID-19 Monkey pox, days like these need planning\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":100601,"journal":{"name":"Health Care Science","volume":"1 2","pages":"129-133"},"PeriodicalIF":0.0,"publicationDate":"2022-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/hcs2.20","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74951134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Implementation science: A critical but undervalued part of the healthcare innovation ecosystem 实施科学:医疗保健创新生态系统中一个关键但被低估的部分
Pub Date : 2022-10-12 DOI: 10.1002/hcs2.22
Sze Ling Chan, Elaine Lum, Marcus E. H. Ong, Nicholas Graves

Healthcare systems face many competing demands and insufficient resources. Service innovations to improve efficiency are important to address this challenge. Innovations can range from new pharmaceuticals, alternate models of care, novel devices, and the use other technologies. Suboptimal implementation can mean lost benefits. This review article aims to highlight the role of implementation science, summarize how settings have leveraged this methodology to promote translation of innovation into practice, and describe our own experience of embedding implementation science into an academic medical center in Singapore. Implementation science offers a range of methods to promote systematic uptake of research findings about innovations and is gaining recognition worldwide as an important discipline for health services researchers. Health systems around the world have tried to promote implementation research in their settings by establishing (1) dedicated centers/programs, (2) offering funding, and (3) building knowledge and capacity among staff. Implementation science is a critical piece in the translational pathway of “evidence to innovation.” The three efforts we describe should be strengthened to integrate implementation science into the innovation ecosystem around the world.

卫生保健系统面临着许多相互竞争的需求和资源不足。提高效率的服务创新对于应对这一挑战至关重要。创新可以包括新的药物、替代的护理模式、新设备和其他技术的使用。次优实现可能意味着失去好处。这篇综述文章旨在强调实施科学的作用,总结设置如何利用这种方法来促进创新转化为实践,并描述我们自己在新加坡学术医疗中心嵌入实施科学的经验。实施科学提供了一系列方法来促进系统地吸收有关创新的研究成果,并作为卫生服务研究人员的一门重要学科在世界范围内得到认可。世界各地的卫生系统都试图通过建立(1)专门的中心/项目,(2)提供资金,以及(3)在工作人员中建立知识和能力来促进实施研究。实施科学是“从证据到创新”这一转化途径的关键部分。我们所描述的三项努力应该得到加强,以将实施科学融入全球的创新生态系统。
{"title":"Implementation science: A critical but undervalued part of the healthcare innovation ecosystem","authors":"Sze Ling Chan,&nbsp;Elaine Lum,&nbsp;Marcus E. H. Ong,&nbsp;Nicholas Graves","doi":"10.1002/hcs2.22","DOIUrl":"10.1002/hcs2.22","url":null,"abstract":"<p>Healthcare systems face many competing demands and insufficient resources. Service innovations to improve efficiency are important to address this challenge. Innovations can range from new pharmaceuticals, alternate models of care, novel devices, and the use other technologies. Suboptimal implementation can mean lost benefits. This review article aims to highlight the role of implementation science, summarize how settings have leveraged this methodology to promote translation of innovation into practice, and describe our own experience of embedding implementation science into an academic medical center in Singapore. Implementation science offers a range of methods to promote systematic uptake of research findings about innovations and is gaining recognition worldwide as an important discipline for health services researchers. Health systems around the world have tried to promote implementation research in their settings by establishing (1) dedicated centers/programs, (2) offering funding, and (3) building knowledge and capacity among staff. Implementation science is a critical piece in the translational pathway of “evidence to innovation.” The three efforts we describe should be strengthened to integrate implementation science into the innovation ecosystem around the world.</p>","PeriodicalId":100601,"journal":{"name":"Health Care Science","volume":"1 3","pages":"160-165"},"PeriodicalIF":0.0,"publicationDate":"2022-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/hcs2.22","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82777241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Xenotransplantation—reflections on the bioethics 异种移植——关于生命伦理学的思考
Pub Date : 2022-10-12 DOI: 10.1002/hcs2.18
Xiaomei Zhai

Background

Similar to most countries in the world, China has a severe shortage of human organs, and this is one of the main issues restricting the application of organ transplantation technology. In 2019 alone, only 19,454 (23.90%) of the 81,410 people waiting were able to receive organ transplants. There is an increasing focus from both the medical profession and society on how to fill the gap between supply and demand.

Methods

Xenotransplantation using animal organs is being considered as one option to make up for the shortage of human organs for transplantation. For some years now, the international medical community has been examining the possibility of using animal organs for human transplant. However, the research has faced two important types of challenges: scientific and ethical issues.

Results

In January 2021, the first clinical trial of transgenic pig heart transplantation into a human recipient was completed by the Medical Center of the University of Maryland in the United States. This has stimulated enthusiasm and interest in xenotransplantation.

Conclusions

The trend towards xenotransplantation has highlighted global problems such as the severe shortage of organ transplant donors and the high cost of organ transplantation. China needs to consider how to cope with the scientific, public health, and social ethics challenges of xenotransplantation clinical trials.

与世界上大多数国家一样,中国存在着严重的人体器官短缺问题,这是制约器官移植技术应用的主要问题之一。仅在2019年,在81410名等待器官移植的患者中,只有19454人(23.90%)能够接受器官移植。医学界和社会越来越关注如何填补供需之间的差距。方法利用动物器官进行异种移植是弥补人体器官短缺的一种选择。多年来,国际医学界一直在研究利用动物器官进行人体移植的可能性。然而,这项研究面临着两种重要的挑战:科学和伦理问题。结果2021年1月,美国马里兰大学医学中心完成了首例转基因猪心脏移植到人类受体的临床试验。这激发了人们对异种器官移植的热情和兴趣。结论异种器官移植的发展趋势凸显了器官供体严重短缺和器官移植费用高等全球性问题。中国需要考虑如何应对异种移植临床试验在科学、公共卫生和社会伦理方面的挑战。
{"title":"Xenotransplantation—reflections on the bioethics","authors":"Xiaomei Zhai","doi":"10.1002/hcs2.18","DOIUrl":"10.1002/hcs2.18","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Similar to most countries in the world, China has a severe shortage of human organs, and this is one of the main issues restricting the application of organ transplantation technology. In 2019 alone, only 19,454 (23.90%) of the 81,410 people waiting were able to receive organ transplants. There is an increasing focus from both the medical profession and society on how to fill the gap between supply and demand.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Xenotransplantation using animal organs is being considered as one option to make up for the shortage of human organs for transplantation. For some years now, the international medical community has been examining the possibility of using animal organs for human transplant. However, the research has faced two important types of challenges: scientific and ethical issues.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>In January 2021, the first clinical trial of transgenic pig heart transplantation into a human recipient was completed by the Medical Center of the University of Maryland in the United States. This has stimulated enthusiasm and interest in xenotransplantation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The trend towards xenotransplantation has highlighted global problems such as the severe shortage of organ transplant donors and the high cost of organ transplantation. China needs to consider how to cope with the scientific, public health, and social ethics challenges of xenotransplantation clinical trials.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100601,"journal":{"name":"Health Care Science","volume":"1 2","pages":"86-92"},"PeriodicalIF":0.0,"publicationDate":"2022-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/hcs2.18","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88355902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
期刊
Health Care Science
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1