Malin Janson, Li Sun, Anja Liebermann, Christoph Matthias Schoppmeier
Objectives
This study evaluated the effect of universal adhesives (UAs) applied as Immediate Dentin Sealing (IDS) on the shear bond strength (SBS) of dual-cure resin cement, both immediately and after thermocycling aging.
Material and Methods
A total of 180 bovine incisors were prepared and randomly assigned to six groups (n = 15): NOC (control), Clearfil Universal Bond Quick (CUBQ), G-Premio Bond (GPB), Peak Universal Bond (PUB), Adhese Universal (AU), and Scotchbond Universal Plus (SBUP). Specimens were cemented with dual-cure resin cement (Panavia V5) and subjected to SBS testing at 24 h and after thermocycling (10,000 cycles, 5°C–55°C). SBS was measured using a universal testing machine, and failure modes were assessed microscopically. Statistical analysis was conducted using a Generalized Linear Model with Bonferroni correction (p < 0.05).
Results
Significant differences were found among UAs (p < 0.001) and after aging (p < 0.001). SBUP and GPB had the highest SBS before and after thermocycling, while NOC had the lowest. Thermocycling reduced SBS in all groups, with CUBQ and AU showing the largest declines. Failure mode analysis showed predominantly adhesive failures in NOC, while IDS groups had more cohesive and mixed failures.
Conclusion
IDS technique with universal adhesives significantly enhances bond strength to dentin compared to conventional cementation. SBUP and GPB showed superior bonding performance, likely due to their monomer formulations containing 10-MDP and acetone, which are known to improve chemical adhesion to dentin and promote effective resin infiltration. Thermocycling led to a reduction in SBS across all groups, highlighting the impact of aging on adhesive durability, underscoring the importance of selecting UAs with lasting adhesive strength for long-term bonding.
{"title":"Impact of Immediate Dentin Sealing With Various Universal Adhesives on Shear Bond Strength of Dual-Cure Resin Cement","authors":"Malin Janson, Li Sun, Anja Liebermann, Christoph Matthias Schoppmeier","doi":"10.1002/cre2.70186","DOIUrl":"https://doi.org/10.1002/cre2.70186","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This study evaluated the effect of universal adhesives (UAs) applied as Immediate Dentin Sealing (IDS) on the shear bond strength (SBS) of dual-cure resin cement, both immediately and after thermocycling aging.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>A total of 180 bovine incisors were prepared and randomly assigned to six groups (<i>n</i> = 15): NOC (control), Clearfil Universal Bond Quick (CUBQ), G-Premio Bond (GPB), Peak Universal Bond (PUB), Adhese Universal (AU), and Scotchbond Universal Plus (SBUP). Specimens were cemented with dual-cure resin cement (Panavia V5) and subjected to SBS testing at 24 h and after thermocycling (10,000 cycles, 5°C–55°C). SBS was measured using a universal testing machine, and failure modes were assessed microscopically. Statistical analysis was conducted using a Generalized Linear Model with Bonferroni correction (<i>p</i> < 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Significant differences were found among UAs (<i>p</i> < 0.001) and after aging (<i>p</i> < 0.001). SBUP and GPB had the highest SBS before and after thermocycling, while NOC had the lowest. Thermocycling reduced SBS in all groups, with CUBQ and AU showing the largest declines. Failure mode analysis showed predominantly adhesive failures in NOC, while IDS groups had more cohesive and mixed failures.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>IDS technique with universal adhesives significantly enhances bond strength to dentin compared to conventional cementation. SBUP and GPB showed superior bonding performance, likely due to their monomer formulations containing 10-MDP and acetone, which are known to improve chemical adhesion to dentin and promote effective resin infiltration. Thermocycling led to a reduction in SBS across all groups, highlighting the impact of aging on adhesive durability, underscoring the importance of selecting UAs with lasting adhesive strength for long-term bonding.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"11 4","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.70186","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144815143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lennart Johannes Gruber, Matthias Maximilian Bühler, Antonie Spillner, Stefan Andreas, Philipp Kauffmann, Henning Schliephake, Susanne Wolfer
Objectives
Tobacco smoking is one major risk factor in the development of oral squamous cell carcinoma (OSCC). Continuation of smoking after diagnosis and treatment is associated with an increase in recurrence rate and incidence of second tumors, with a shorter lon g-term survival and poorer response to therapy. In the current German guideline for the treatment of OSCC, there is no clear recommendation to participate in structured smoking cessation programs.
Materials and Methods
A total of 202 patients with histologically confirmed OSCC completed a one-time assessment of their smoking behavior using three standardized questionnaires during regular tumor follow-up. In addition to sociodemographic data, patients were asked retrospectively about their smoking habits and motivation to quit smoking before and after diagnosis and treatment.
Results
A serious smoking cessation attempt before diagnosis of OSCC were stated in 54.8% of the participants. This number increased up to 82.2% after OSCC diagnosis. However, only 48.5% managed to quit smoking after diagnosis. Professional support was with only 21.92% (n = 16) rarely used. Motivation to quit was significantly lower before (2.75 ± 2.41) than after OSCC diagnosis (7.27 ± 2.41) (p = 0.001) and significantly higher among the participants who finally managed to quit (9.38 ± 1.68) than among those who continued smoking (4.79 ± 3.43) (p = 0.001).
Conclusions
The diagnosis of OSCC appears to be an important teachable moment for smoking cessation. To maximize this effect, an early and standardized implementation of systematic smoking cessation programs into the therapeutic concept of patients with OSCC is strongly recommended.
{"title":"Motivation for Smoking Cessation in Patients With Oral Squamous Cell Carcinoma—A One-Time Survey","authors":"Lennart Johannes Gruber, Matthias Maximilian Bühler, Antonie Spillner, Stefan Andreas, Philipp Kauffmann, Henning Schliephake, Susanne Wolfer","doi":"10.1002/cre2.70154","DOIUrl":"https://doi.org/10.1002/cre2.70154","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Tobacco smoking is one major risk factor in the development of oral squamous cell carcinoma (OSCC). Continuation of smoking after diagnosis and treatment is associated with an increase in recurrence rate and incidence of second tumors, with a shorter lon g-term survival and poorer response to therapy. In the current German guideline for the treatment of OSCC, there is no clear recommendation to participate in structured smoking cessation programs.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>A total of 202 patients with histologically confirmed OSCC completed a one-time assessment of their smoking behavior using three standardized questionnaires during regular tumor follow-up. In addition to sociodemographic data, patients were asked retrospectively about their smoking habits and motivation to quit smoking before and after diagnosis and treatment.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A serious smoking cessation attempt before diagnosis of OSCC were stated in 54.8% of the participants. This number increased up to 82.2% after OSCC diagnosis. However, only 48.5% managed to quit smoking after diagnosis. Professional support was with only 21.92% (<i>n</i> = 16) rarely used. Motivation to quit was significantly lower before (2.75 ± 2.41) than after OSCC diagnosis (7.27 ± 2.41) (<i>p</i> = 0.001) and significantly higher among the participants who finally managed to quit (9.38 ± 1.68) than among those who continued smoking (4.79 ± 3.43) (<i>p</i> = 0.001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The diagnosis of OSCC appears to be an important teachable moment for smoking cessation. To maximize this effect, an early and standardized implementation of systematic smoking cessation programs into the therapeutic concept of patients with OSCC is strongly recommended.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"11 4","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.70154","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144809244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emilio Salerno, Silvio Abati, Gianluigi Arrigoni, Daniela Finocchiaro, Giorgio Gastaldi, Alessandra Lissoni, Andrea Galli, Matteo Trimarchi
Objectives
The primary objective of this study is to report and analyze two rare cases of secretory carcinoma (SC) of the minor salivary glands, focusing on their diagnostic and therapeutic work-up. The study aims to enhance scientific knowledge about SC, which is crucial for developing targeted therapies and ensuring precise diagnosis, especially differentiating it from acinic cell carcinoma (ACC).
Materials and Methods
The study involved a detailed examination of two patients diagnosed with SC of the minor salivary glands. Clinical examinations, histological investigations, and immunohistochemical analyses were conducted. The treatment approach included surgical excision of the lesions followed by regular follow-ups to monitor for recurrence. Immunohistochemical analysis was performed to identify the presence of markers such as GATA3, SOX-10, NTRK, mammaglobin, and others.
Results
Two cases are shown: a case of a 76-year-old male with a lesion in the hard palate was initially misdiagnosed as leukoplakia. After surgical excision and histological examination, the lesion was identified as SC. The patient underwent follow-up examinations, including MRI and CT scans, which showed no recurrence, and another case of a 39-year-old female with a nodule in the superior left vestibule underwent surgery to remove the nodule. Histological and immunohistochemical analyses confirmed SC, showing a high proliferation index and presence of the ETV6–NTRK3 gene fusion. Follow-up imaging showed no signs of disease recurrence.
Conclusions
The study underscores the importance of precise diagnosis and differentiation of SC from ACC. Surgical excision followed by regular monitoring is effective in managing SC. Immunohistochemical and molecular analyses are crucial for accurate diagnosis. The findings contribute to the growing body of evidence on SC and highlight the potential for developing more targeted therapies. Further research is needed to establish clear guidelines for follow-up duration and treatment protocols.
{"title":"Rare Tumors of Oral Cavity: A Case Report and Literature Review on Secretory Carcinoma of Minor Salivary Glands","authors":"Emilio Salerno, Silvio Abati, Gianluigi Arrigoni, Daniela Finocchiaro, Giorgio Gastaldi, Alessandra Lissoni, Andrea Galli, Matteo Trimarchi","doi":"10.1002/cre2.70200","DOIUrl":"https://doi.org/10.1002/cre2.70200","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>The primary objective of this study is to report and analyze two rare cases of secretory carcinoma (SC) of the minor salivary glands, focusing on their diagnostic and therapeutic work-up. The study aims to enhance scientific knowledge about SC, which is crucial for developing targeted therapies and ensuring precise diagnosis, especially differentiating it from acinic cell carcinoma (ACC).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>The study involved a detailed examination of two patients diagnosed with SC of the minor salivary glands. Clinical examinations, histological investigations, and immunohistochemical analyses were conducted. The treatment approach included surgical excision of the lesions followed by regular follow-ups to monitor for recurrence. Immunohistochemical analysis was performed to identify the presence of markers such as GATA3, SOX-10, NTRK, mammaglobin, and others.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Two cases are shown: a case of a 76-year-old male with a lesion in the hard palate was initially misdiagnosed as leukoplakia. After surgical excision and histological examination, the lesion was identified as SC. The patient underwent follow-up examinations, including MRI and CT scans, which showed no recurrence, and another case of a 39-year-old female with a nodule in the superior left vestibule underwent surgery to remove the nodule. Histological and immunohistochemical analyses confirmed SC, showing a high proliferation index and presence of the ETV6–NTRK3 gene fusion. Follow-up imaging showed no signs of disease recurrence.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The study underscores the importance of precise diagnosis and differentiation of SC from ACC. Surgical excision followed by regular monitoring is effective in managing SC. Immunohistochemical and molecular analyses are crucial for accurate diagnosis. The findings contribute to the growing body of evidence on SC and highlight the potential for developing more targeted therapies. Further research is needed to establish clear guidelines for follow-up duration and treatment protocols.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"11 4","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.70200","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144773888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
William Weng Nian Mak, Sushil Kaur, Maurice J. Meade
Objective
To investigate the quality of online information provided by dental-related websites regarding periodontal surgery.
Methods
The term “Gum Surgery” was entered into three search engines (Google, Yahoo, and Bing). The content of websites satisfying selection criteria was assessed with five validated quality of information tools (DISCERN, The Patient Education Materials Assessment Tool [PEMAT], Journal of the American Medical Association [JAMA] benchmarks, and HONCode and @TRUST certification). The Simple Measure of Gobbledygook (SMOG) was used to evaluate the readability of content.
Results
A total of 55 websites satisfied selection criteria. The mean (SD) DISCERN score for all website categories was 2.89 (0.57). The quality of information related to the risks of each treatment scored poorly in most websites. The healthcare portals obtained the highest mean PEMAT score of 71.74%, a statistically significant outcome. Healthcare portal websites also recorded the highest mean (SD) JAMA score of 3.72 (0.75) out of 4. The mean (SD) SMOG score was 9.56 (1.07). Cohen's κ inter-rater reliability for DISCERN and PEMAT scores were 0.75 and 0.79, respectively.
Conclusion
The information available online about periodontal surgery was variable and difficult to read, falling short of established standards for accuracy, reliability, and credibility. Vital information was often omitted.
{"title":"A Cross-Sectional Study of the Quality of Online Information on Periodontal Surgery","authors":"William Weng Nian Mak, Sushil Kaur, Maurice J. Meade","doi":"10.1002/cre2.70195","DOIUrl":"https://doi.org/10.1002/cre2.70195","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To investigate the quality of online information provided by dental-related websites regarding periodontal surgery.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The term “Gum Surgery” was entered into three search engines (Google, Yahoo, and Bing). The content of websites satisfying selection criteria was assessed with five validated quality of information tools (DISCERN, The Patient Education Materials Assessment Tool [PEMAT], Journal of the American Medical Association [JAMA] benchmarks, and HONCode and @TRUST certification). The Simple Measure of Gobbledygook (SMOG) was used to evaluate the readability of content.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 55 websites satisfied selection criteria. The mean (SD) DISCERN score for all website categories was 2.89 (0.57). The quality of information related to the risks of each treatment scored poorly in most websites. The healthcare portals obtained the highest mean PEMAT score of 71.74%, a statistically significant outcome. Healthcare portal websites also recorded the highest mean (SD) JAMA score of 3.72 (0.75) out of 4. The mean (SD) SMOG score was 9.56 (1.07). Cohen's <i>κ</i> inter-rater reliability for DISCERN and PEMAT scores were 0.75 and 0.79, respectively.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The information available online about periodontal surgery was variable and difficult to read, falling short of established standards for accuracy, reliability, and credibility. Vital information was often omitted.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"11 4","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.70195","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144773724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bone repair and regeneration are important processes for treating bone defects and injuries. However, traditional bone grafts like autografts and allografts have limitations, such as complications at the donor site and immune rejection. As a result, there is growing interest in using polylactic acid (PLA), a biodegradable and biocompatible material, as a synthetic bone substitute. This study aims to evaluate the effectiveness of 3D-printed PLA scaffolds as bone substitutes using a rat model.
Material and Methods
PLA scaffolds with dimensions of 2 × 2 × 4 mm and 2 × 2 × 8 mm were fabricated using the CUBEX-TRIO 3D printer. Twelve male Wistar rats were divided into four groups based on defect size (4 and 8 mm) and observation period (4 weeks and 8 weeks). The surgical procedures involved creating discontinuity defects in the rats' zygoma and implanting PLA scaffolds that were stabilized with a bio-membrane. Bone regeneration was assessed through radiographic analysis and histological examination.
Results
Radiographic analysis confirmed the formation of bone in the grafted regions. Histological analysis revealed connective tissue formation at the defect edges and scaffold surface at both 4 and 8 weeks. In the 4 mm defect group, the transformation of connective tissue into chondrocytes and endochondral ossification was observed at 8 weeks, indicating successful bone regeneration. However, in the 8 mm defect group, bone formation was not as evident, suggesting limitations in the osteoinductive potential of PLA scaffolds for larger defects.
Conclusions
The 3D-printed PLA scaffolds show promise as bone substitutes for small to moderate-sized defects due to their effective biocompatibility and osteoinductive potential. Further studies are needed to optimize their performance for larger defects, potentially enhancing their clinical application in bone repair and regeneration.
{"title":"Evaluation of 3D-Printed Polylactic Acid as a Bone Substitute: An Animal Study in a Rat Model","authors":"Velayudhan Ashok, Mohanraj Karthik Ganesh, Subhabrata Maiti, Deepak Nallaswamy, Artak Heboyan","doi":"10.1002/cre2.70201","DOIUrl":"https://doi.org/10.1002/cre2.70201","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Bone repair and regeneration are important processes for treating bone defects and injuries. However, traditional bone grafts like autografts and allografts have limitations, such as complications at the donor site and immune rejection. As a result, there is growing interest in using polylactic acid (PLA), a biodegradable and biocompatible material, as a synthetic bone substitute. This study aims to evaluate the effectiveness of 3D-printed PLA scaffolds as bone substitutes using a rat model.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>PLA scaffolds with dimensions of 2 × 2 × 4 mm and 2 × 2 × 8 mm were fabricated using the CUBEX-TRIO 3D printer. Twelve male Wistar rats were divided into four groups based on defect size (4 and 8 mm) and observation period (4 weeks and 8 weeks). The surgical procedures involved creating discontinuity defects in the rats' zygoma and implanting PLA scaffolds that were stabilized with a bio-membrane. Bone regeneration was assessed through radiographic analysis and histological examination.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Radiographic analysis confirmed the formation of bone in the grafted regions. Histological analysis revealed connective tissue formation at the defect edges and scaffold surface at both 4 and 8 weeks. In the 4 mm defect group, the transformation of connective tissue into chondrocytes and endochondral ossification was observed at 8 weeks, indicating successful bone regeneration. However, in the 8 mm defect group, bone formation was not as evident, suggesting limitations in the osteoinductive potential of PLA scaffolds for larger defects.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The 3D-printed PLA scaffolds show promise as bone substitutes for small to moderate-sized defects due to their effective biocompatibility and osteoinductive potential. Further studies are needed to optimize their performance for larger defects, potentially enhancing their clinical application in bone repair and regeneration.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"11 4","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.70201","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144773725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rashad I. Shaadouh, Mohammad Y. Hajeer, Mohammad Khursheed Alam, Samer T. Jaber
<div> <section> <h3> Objective</h3> <p>To evaluate external apical root resorption (EARR) and periodontal indices during en-masse retraction of maxillary anterior teeth stimulated with low-intensity electrical currents.</p> </section> <section> <h3> Trial Design</h3> <p>A two-arm randomized controlled trial.</p> </section> <section> <h3> Methods</h3> <p>Young adult patients who visited the Department of Orthodontics at Damascus University between November 2023 and March 2024 and met predefined inclusion criteria were randomly allocated into two groups using block randomization. The study included 34 patients, with 17 assigned to the electrically stimulated en-masse retraction (ESER) group and 17 to the conventional en-masse retraction (CER) group. The force for the en-masse retraction technique in both groups was 250 g per side. The force was applied through bilateral closed-coil nickel-titanium springs anchored to an orthodontic mini-screw on each side. In the ESER group, each upper anterior tooth was subjected to a continuous electrical stimulation of 15–20 µA for 5 h daily, utilizing an intraoral removable electrical stimulation device. EARR was assessed using digital panoramic radiographs. Four periodontal indices were also used to assess periodontal status. Blinding was confined to data analysis.</p> </section> <section> <h3> Results</h3> <p>Thirty-four patients (26 females and 8 males) were analyzed with a mean age of 21.12 ± 2.41 years. At the end of the en-masse retraction phase, no significant difference in EARR was observed between the two groups (<i>p</i> > 0.05). The observed root resorption in the ESER and CER ranged between 0.27 and 0.64 and 0.32 and 0.71 mm, respectively. Also, insignificant differences were found in all periodontal indices studied at all measurement points between the two groups (<i>p</i> > 0.05).</p> </section> <section> <h3> Conclusions</h3> <p>Low-intensity electrical stimulation had no significant effect on root resorption during the en-masse retraction of the six upper anterior teeth. Both groups exhibited comparable slight root resorption without any significant difference between them. Additionally, low-intensity electrical stimulation did not affect the periodontal status during en-masse retraction.</p> </section> <section> <h3> Trail Registration</h3> <p>Clinical Trials database (NCT06873490).</p>
{"title":"Effect of Low-Intensity Electrical Stimulation on External Apical Root Resorption and Periodontal Indices Following En-Masse Retraction of Upper Anterior Teeth in Young Adults: A Randomized Controlled Trial","authors":"Rashad I. Shaadouh, Mohammad Y. Hajeer, Mohammad Khursheed Alam, Samer T. Jaber","doi":"10.1002/cre2.70188","DOIUrl":"https://doi.org/10.1002/cre2.70188","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To evaluate external apical root resorption (EARR) and periodontal indices during en-masse retraction of maxillary anterior teeth stimulated with low-intensity electrical currents.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Trial Design</h3>\u0000 \u0000 <p>A two-arm randomized controlled trial.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Young adult patients who visited the Department of Orthodontics at Damascus University between November 2023 and March 2024 and met predefined inclusion criteria were randomly allocated into two groups using block randomization. The study included 34 patients, with 17 assigned to the electrically stimulated en-masse retraction (ESER) group and 17 to the conventional en-masse retraction (CER) group. The force for the en-masse retraction technique in both groups was 250 g per side. The force was applied through bilateral closed-coil nickel-titanium springs anchored to an orthodontic mini-screw on each side. In the ESER group, each upper anterior tooth was subjected to a continuous electrical stimulation of 15–20 µA for 5 h daily, utilizing an intraoral removable electrical stimulation device. EARR was assessed using digital panoramic radiographs. Four periodontal indices were also used to assess periodontal status. Blinding was confined to data analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Thirty-four patients (26 females and 8 males) were analyzed with a mean age of 21.12 ± 2.41 years. At the end of the en-masse retraction phase, no significant difference in EARR was observed between the two groups (<i>p</i> > 0.05). The observed root resorption in the ESER and CER ranged between 0.27 and 0.64 and 0.32 and 0.71 mm, respectively. Also, insignificant differences were found in all periodontal indices studied at all measurement points between the two groups (<i>p</i> > 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Low-intensity electrical stimulation had no significant effect on root resorption during the en-masse retraction of the six upper anterior teeth. Both groups exhibited comparable slight root resorption without any significant difference between them. Additionally, low-intensity electrical stimulation did not affect the periodontal status during en-masse retraction.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Trail Registration</h3>\u0000 \u0000 <p>Clinical Trials database (NCT06873490).</p>\u0000 ","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"11 4","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.70188","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144773889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study investigated the effects of various application methods of silver diamine fluoride (SDF) on dentin microhardness and its durability under a 14-day acid challenge. The primary goal was to identify an optimal conservative SDF application protocol for clinical dentistry.
Material and Methods
Mid-coronal dentin disc samples from human premolars were prepared through two horizontal cuts and polished. Samples were randomly divided into three groups of ten: (1) SDF-NR (SDF applied for 3 min, excess removed with cotton); (2) SDF-R-R (SDF applied, rinsed, and polished after 24 h); (3) SDF-R (SDF applied for 3 min, then rinsed). Vickers microhardness was measured at three stages: initial, post-demineralization, and post-SDF application. In the second phase, a control group (no SDF) and a test group (SDF-R) underwent a 14-day pH-cycling regimen, with final hardness changes evaluated at a significance level of 0.05.
Results
Significant microhardness increases were observed in all groups following SDF application compared to demineralized conditions (p = 0.001). Although the decrease in microhardness after acid challenge in the SDF group was less than in the control group, this difference was not statistically significant (p = 0.423).
Conclusion
Different SDF application methods significantly enhance dentin microhardness post-demineralization. Nevertheless, the acid challenge revealed minimal differences between the control and test group, indicating that reapplication of SDF may be necessary for sustained effectiveness.
目的研究氟化二胺银（SDF）不同涂敷方式对牙本质显微硬度及其在14 d酸胁迫下耐久性的影响。主要目的是为临床牙科确定一个最佳的保守的SDF应用方案。材料与方法采用两次水平切割和抛光法制备人前磨牙中冠牙本质盘样品。样本随机分为三组，每组10人：(1)SDF- nr （SDF作用3 min，多余部分用棉花除去）；(2) SDF- r - r （SDF涂抹、冲洗、抛光24小时后）；(3) SDF- r （SDF应用3分钟，然后冲洗）。在三个阶段测量维氏显微硬度：初始、脱矿后和sdf应用后。在第二阶段，对照组（无SDF）和试验组（SDF- r）进行14天的ph循环治疗，最终硬度变化在0.05的显著水平上进行评估。结果与脱矿条件相比，应用SDF后，所有组的显微硬度均显著增加（p = 0.001）。虽然SDF组酸激后显微硬度的下降幅度小于对照组，但差异无统计学意义（p = 0.423）。结论不同的SDF应用方法可显著提高脱矿后牙本质显微硬度。然而，酸攻击显示对照组和试验组之间的差异很小，这表明为了持续有效，可能需要重新施用SDF。
{"title":"Effect of Silver Diamine Fluoride Application Methods on Dentin Microhardness and Durability Under pH Cycling: An In Vitro Study","authors":"Farideh Darabi, Parmida Farzam, Mehrsima Ghavami-Lahiji","doi":"10.1002/cre2.70190","DOIUrl":"https://doi.org/10.1002/cre2.70190","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This study investigated the effects of various application methods of silver diamine fluoride (SDF) on dentin microhardness and its durability under a 14-day acid challenge. The primary goal was to identify an optimal conservative SDF application protocol for clinical dentistry.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>Mid-coronal dentin disc samples from human premolars were prepared through two horizontal cuts and polished. Samples were randomly divided into three groups of ten: (1) SDF-NR (SDF applied for 3 min, excess removed with cotton); (2) SDF-R-R (SDF applied, rinsed, and polished after 24 h); (3) SDF-R (SDF applied for 3 min, then rinsed). Vickers microhardness was measured at three stages: initial, post-demineralization, and post-SDF application. In the second phase, a control group (no SDF) and a test group (SDF-R) underwent a 14-day pH-cycling regimen, with final hardness changes evaluated at a significance level of 0.05.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Significant microhardness increases were observed in all groups following SDF application compared to demineralized conditions (<i>p</i> = 0.001). Although the decrease in microhardness after acid challenge in the SDF group was less than in the control group, this difference was not statistically significant (<i>p</i> = 0.423).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Different SDF application methods significantly enhance dentin microhardness post-demineralization. Nevertheless, the acid challenge revealed minimal differences between the control and test group, indicating that reapplication of SDF may be necessary for sustained effectiveness.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"11 4","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.70190","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144740224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sindi Vishaj, Alissa Villhauer, Mandi Morris, Donald M. Belles, Daher Antonio Queiroz, Maria D. Gonzalez, Ransome van der Hoeven
Objectives
This study aimed to evaluate the antimicrobial efficacy of three commercially available denture cleaning tablets Efferdent, Polident, and Val-clean against Staphylococcus aureus biofilms formed on two denture base materials: milled polymethyl methacrylate (PMMA) and 3D printed denture resin.
Material and Methods
Eighty samples were fabricated, with 40 specimens per denture base material: CAD/CAM milled PMMA (Lucitone Digital Fit LT; Dentsply Sirona, Charlotte, NC, USA) and 3D printed resin (Denture Base Resin; Formlabs Inc., Somerville, MA, USA). Each group was divided into four subgroups (n = 10), Efferdent, Polident, Val-clean, and deionized water (control). Surface roughness was measured using a digital profilometer (Digiprofilo I; Digiwork Instruments, Concord, ON, Canada). Samples were exposed to S. aureus in tryptic soy broth (TSB) and subsequently treated with the cleaning solutions. Colony-forming units (CFUs) were quantified using serial dilution plating. To distinguish bactericidal from bacteriostatic effects, normalized S. aureus cultures were incubated with the cleaning agents for 16 h, followed by optical density measurements, LIVE/DEAD staining (Invitrogen, Carlsbad, California), and TSB agar plating. Statistical analysis was performed using one-way ANOVA and Dunnett's multiple comparisons test, with significance set at p < 0.05.
Results
A significant difference in surface roughness was observed between the 3D printed and milled samples before treatment (p < 0.0001). Significantly fewer CFUs were observed in all cleaning solution groups compared to the control (p < 0.05). All denture cleaning solutions demonstrated bactericidal activity against S. aureus, as indicated by the absence of CFU growth on agar plates and the lack of viable cells in LIVE/DEAD staining posttreatment. Both denture materials demonstrated comparable microbial adhesion and response to the cleaning agents.
Conclusions
Efferdent, Polident, and Val-clean denture tablets are effective bactericidal agents against S. aureus in vitro, regardless of the denture base material used. These findings support their use in daily denture hygiene routines, particularly in reducing bacterial colonization on removable prostheses.
{"title":"Evaluating the Antimicrobial Properties of Different Dental Cleaning Tablets Against S. aureus Grown on Two Denture Base Materials","authors":"Sindi Vishaj, Alissa Villhauer, Mandi Morris, Donald M. Belles, Daher Antonio Queiroz, Maria D. Gonzalez, Ransome van der Hoeven","doi":"10.1002/cre2.70189","DOIUrl":"https://doi.org/10.1002/cre2.70189","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This study aimed to evaluate the antimicrobial efficacy of three commercially available denture cleaning tablets Efferdent, Polident, and Val-clean against <i>Staphylococcus aureus</i> biofilms formed on two denture base materials: milled polymethyl methacrylate (PMMA) and 3D printed denture resin.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>Eighty samples were fabricated, with 40 specimens per denture base material: CAD/CAM milled PMMA (Lucitone Digital Fit LT; Dentsply Sirona, Charlotte, NC, USA) and 3D printed resin (Denture Base Resin; Formlabs Inc., Somerville, MA, USA). Each group was divided into four subgroups (<i>n</i> = 10), Efferdent, Polident, Val-clean, and deionized water (control). Surface roughness was measured using a digital profilometer (Digiprofilo I; Digiwork Instruments, Concord, ON, Canada). Samples were exposed to <i>S. aureus</i> in tryptic soy broth (TSB) and subsequently treated with the cleaning solutions. Colony-forming units (CFUs) were quantified using serial dilution plating. To distinguish bactericidal from bacteriostatic effects, normalized <i>S. aureus</i> cultures were incubated with the cleaning agents for 16 h, followed by optical density measurements, LIVE/DEAD staining (Invitrogen, Carlsbad, California), and TSB agar plating. Statistical analysis was performed using one-way ANOVA and Dunnett's multiple comparisons test, with significance set at <i>p</i> < 0.05.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A significant difference in surface roughness was observed between the 3D printed and milled samples before treatment (<i>p</i> < 0.0001). Significantly fewer CFUs were observed in all cleaning solution groups compared to the control (<i>p</i> < 0.05). All denture cleaning solutions demonstrated bactericidal activity against <i>S. aureus</i>, as indicated by the absence of CFU growth on agar plates and the lack of viable cells in LIVE/DEAD staining posttreatment. Both denture materials demonstrated comparable microbial adhesion and response to the cleaning agents.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Efferdent, Polident, and Val-clean denture tablets are effective bactericidal agents against <i>S. aureus</i> in vitro, regardless of the denture base material used. These findings support their use in daily denture hygiene routines, particularly in reducing bacterial colonization on removable prostheses.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"11 4","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.70189","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144740222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mobile applications are becoming essential for speech therapy, especially in areas with limited access to professional speech therapists. This technological intervention is especially pertinent during pandemics, which further restrict access to traditional therapeutic modalities. The objective of this study was to develop and evaluate a mobile application for articulation therapy, specifically designed for pediatric patients with articulation disorders associated with cleft palate.
Material and Methods
The articulation exercises incorporated in the application encompassed 27 Thai initial and final consonant sounds, presented through video demonstrations and tabular reading materials. These materials included nonsense syllables, words, phrases, and sentences. The content validity was assessed using the Item-Objective Congruence (IOC) index. Face validity and functional satisfaction were evaluated by a panel comprising four speech-language pathologists (SLPs), five children with cleft palate with or without cleft lip (CP ± L) and their respective caregivers, and an expert in application design. The clinical efficacy of the application for speech correction was subsequently assessed in a cohort of 19 children diagnosed with CP ± L.
Results
The Application for Articulation Therapy-Thai (AAT-T) was finalized after four iterative revisions. The IOC index for the application ranged from 0.80 to 1.00, indicating strong content validity. Functional satisfaction scores ranged from 76% to 100%, suggesting high user acceptability. Nineteen children participated in the clinical efficacy assessment; however, one child was withdrawn due to the inability to complete 6-month follow-up. The results demonstrated that AAT-T significantly reduced articulation errors in connected speech (mean difference = 2.33, SD = 2.40, 95% CI = 1.14–3.53, p < 0.001).
Conclusions
The AAT-T application emerged as an accessible, engaging, and motivational tool for articulation practice. Its efficacy in speech correction was demonstrated.
移动应用程序对语言治疗越来越重要，特别是在专业语言治疗师有限的地区。这种技术干预在大流行病期间尤为重要，因为大流行病进一步限制了人们获得传统治疗方式的机会。本研究的目的是开发和评估一款专门为腭裂相关的儿童发音障碍患者设计的发音治疗移动应用程序。材料和方法应用程序中包含的发音练习包括27个泰语声母和韵母，通过视频演示和表格阅读材料呈现。这些材料包括无意义的音节、单词、短语和句子。采用项目-客观一致性（IOC）指标评估内容效度。面部有效性和功能满意度由四名言语语言病理学家（slp）、五名腭裂伴或非唇裂儿童（CP±L）及其各自的护理人员和一名应用程序设计专家组成的小组进行评估。随后在19名诊断为CP±L的儿童中评估了应用言语矫正的临床疗效。结果经4次反复修订，最终确定了《关节治疗泰式应用程序》（AAT-T）。应用程序的IOC指数在0.80到1.00之间，表明内容效度较强。功能满意度评分从76%到100%不等，用户接受度高。19例患儿参与临床疗效评估；然而，一名儿童因无法完成6个月的随访而退出。结果表明，AAT-T显著减少了连接语音的发音错误（平均差值= 2.33,SD = 2.40, 95% CI = 1.14-3.53, p < 0.001）。结论：AAT-T的应用是一种易于使用的、有吸引力的、有动机的发音练习工具。证明了其在言语矫正中的有效性。
{"title":"Development and Clinical Efficacy of the Application for Articulation Therapy-Thai (AAT-T) for Thai Children With Cleft Lip and Palate","authors":"Benjamas Prathanee, Sumita Duangprasert, Sasalaksamon Chanachai, Patorn Piromchai","doi":"10.1002/cre2.70194","DOIUrl":"https://doi.org/10.1002/cre2.70194","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Mobile applications are becoming essential for speech therapy, especially in areas with limited access to professional speech therapists. This technological intervention is especially pertinent during pandemics, which further restrict access to traditional therapeutic modalities. The objective of this study was to develop and evaluate a mobile application for articulation therapy, specifically designed for pediatric patients with articulation disorders associated with cleft palate.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>The articulation exercises incorporated in the application encompassed 27 Thai initial and final consonant sounds, presented through video demonstrations and tabular reading materials. These materials included nonsense syllables, words, phrases, and sentences. The content validity was assessed using the Item-Objective Congruence (IOC) index. Face validity and functional satisfaction were evaluated by a panel comprising four speech-language pathologists (SLPs), five children with cleft palate with or without cleft lip (CP ± L) and their respective caregivers, and an expert in application design. The clinical efficacy of the application for speech correction was subsequently assessed in a cohort of 19 children diagnosed with CP ± L.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The Application for Articulation Therapy-Thai (AAT-T) was finalized after four iterative revisions. The IOC index for the application ranged from 0.80 to 1.00, indicating strong content validity. Functional satisfaction scores ranged from 76% to 100%, suggesting high user acceptability. Nineteen children participated in the clinical efficacy assessment; however, one child was withdrawn due to the inability to complete 6-month follow-up. The results demonstrated that AAT-T significantly reduced articulation errors in connected speech (mean difference = 2.33, SD = 2.40, 95% CI = 1.14–3.53, <i>p</i> < 0.001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The AAT-T application emerged as an accessible, engaging, and motivational tool for articulation practice. Its efficacy in speech correction was demonstrated.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"11 4","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.70194","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144740223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lin Jing Uei, Xin Hui Yeo, Yiu Yan Leung, George Pelekos, Bilal Al Nawas, Nikos Mattheos
Objective
This white paper aimed to discuss educational strategies for teaching and learning of computer-assisted implant surgery (CAIS) within the wider dental curriculum, including the pedagogy, technologies, and challenges.
Material and Methods
A review of the available literature up to February 2025 was conducted, compiling existing evidence related to the application of CAIS in dental education, both through simulation and in clinical care. The findings were further integrated with expert opinions and current best practices in dental education in a panel discussion.
Results
Guided CAIS demonstrated potential to enhance implant placement accuracy and increase confidence among novice surgeons. Dynamic CAIS (d-CAIS) could support broader cognitive and surgical skill development, whereas static CAIS (s-CAIS) showed limited utility as a comprehensive educational instrument. The sequence of learning between guided and non-guided techniques appears to be less critical than ensuring proficiency in both. Competence development with d-CAIS is incremental, unlike s-CAIS, where progress might be faster but involves mainly procedural skills. Key challenges remain for the implementation of CAIS in educational structures such as limited faculty expertise, high costs of digital equipment, limited interoperability of digital systems, and ethical or legal concerns regarding autonomy of technologies.
Conclusion
CAIS has shown to be a valuable tool in teaching implant dentistry; its proper integration into dental education enhances the learners' experience and offers significant benefits for developing overall surgical competences. Current educational research is limited and primarily focused on the accuracy of implant placement, while practice of CAIS entails a very wide set of parameters encompassing the clinician, the workflow, the institution or clinic, and the patient. Future studies targeting educational interventions with a wider array of outcome measures would be required to help design effective educational strategies with CAIS.
{"title":"Computer-Assisted Implant Surgery: Implications for Teaching, Learning, and Educational Strategies","authors":"Lin Jing Uei, Xin Hui Yeo, Yiu Yan Leung, George Pelekos, Bilal Al Nawas, Nikos Mattheos","doi":"10.1002/cre2.70197","DOIUrl":"https://doi.org/10.1002/cre2.70197","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>This white paper aimed to discuss educational strategies for teaching and learning of computer-assisted implant surgery (CAIS) within the wider dental curriculum, including the pedagogy, technologies, and challenges.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>A review of the available literature up to February 2025 was conducted, compiling existing evidence related to the application of CAIS in dental education, both through simulation and in clinical care. The findings were further integrated with expert opinions and current best practices in dental education in a panel discussion.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Guided CAIS demonstrated potential to enhance implant placement accuracy and increase confidence among novice surgeons. Dynamic CAIS (d-CAIS) could support broader cognitive and surgical skill development, whereas static CAIS (s-CAIS) showed limited utility as a comprehensive educational instrument. The sequence of learning between guided and non-guided techniques appears to be less critical than ensuring proficiency in both. Competence development with d-CAIS is incremental, unlike s-CAIS, where progress might be faster but involves mainly procedural skills. Key challenges remain for the implementation of CAIS in educational structures such as limited faculty expertise, high costs of digital equipment, limited interoperability of digital systems, and ethical or legal concerns regarding autonomy of technologies.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>CAIS has shown to be a valuable tool in teaching implant dentistry; its proper integration into dental education enhances the learners' experience and offers significant benefits for developing overall surgical competences. Current educational research is limited and primarily focused on the accuracy of implant placement, while practice of CAIS entails a very wide set of parameters encompassing the clinician, the workflow, the institution or clinic, and the patient. Future studies targeting educational interventions with a wider array of outcome measures would be required to help design effective educational strategies with CAIS.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"11 4","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.70197","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144740221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
扫码关注我们
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号