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Comparison of diagnostic tools to assess the feasibility of programmatic use of rapid diagnostic tests for onchocerciasis: A dataset from Gabon 比较诊断工具,评估盘尾丝虫病快速诊断检测在计划中使用的可行性:加蓬数据集
IF 1 Q3 MULTIDISCIPLINARY SCIENCES Pub Date : 2024-09-06 DOI: 10.1016/j.dib.2024.110901

Due to the success of large-scale ivermectin mass drug administration (MDA), the aim of onchocerciasis intervention efforts have shifted from control of the disease to elimination of transmission. This has necessitated a greater understanding and comparison of the performance of diagnostic tools in hypoendemic (low prevalence) settings which had not been incorporated into large-scale MDA programmes before the goal switched from onchocerciasis elimination as a public health problem to elimination (interruption) of transmission (EOT). Data on age, sex and duration of residence were collected, prior to ivermectin treatment, across Gabon in 2015 from 5,829 participants in 67 communities from 14 districts. Skin-snip samples (for detection of Onchocerca volvulus microfilariae) were obtained from 4,350 (75 %) and blood samples (for detection of presence of IgG4 antibodies against the O. volvulus Ov16 antigen) from 4,257 of those skin-snip tested (98 %).

Whole blood was tested in the field using the SD Ov16 Rapid Diagnostic Test Prototype (Ov16 RDT). Dried blood spots (DBS) were prepared for all blood-sampled individuals. After assessing DBS quality, 2,990 (70 %) samples underwent valid analysis in the lab using horseradish peroxidase (HRP) Ov16 enzyme-linked immunosorbent assay (Ov16 ELISA). The number of positive individuals varied between diagnostic tools with skin-snip microscopy, Ov16 RDT and Ov16 ELISA detecting 337/4,350 (8 %, 95 % CI =7 %–9 %), 383/4,257 (9 %, 8 %–10 %) and 348/2,990 (12 %, 10 %–13 %), respectively. Data were analysed to understand the age profiles of microfilarial and IgG4 antibody prevalence by diagnostic and mapped across Gabon.

These data have reuse potential for policy makers, test manufacturers and country programmes when making determinations at community level of the suitability of using Ov16 RDT for conducting delineation mapping or evaluating the current stage of a community or, more generally, an evaluation unit along the EOT path. Further, these data are of use to transmission dynamics modellers who can fit models to these data to better understand the stage(s) in the O. volvulus lifecycle likely responsible for IgG4 antibody seroconversion in the presence of Ov16 antigen. This is crucial for incorporation of antibody prevalence as an output of onchocerciasis transmission models to permit evaluation of currently proposed serological thresholds to inform decisions about Start- or Stop-MDA in the context of onchocerciasis elimination mapping (OEM) and verification of EOT, respectively.

由于大规模伊维菌素大规模用药(MDA)取得了成功,盘尾丝虫病干预工作的目标已从控制疾病转变为消除传播。因此,有必要进一步了解和比较诊断工具在低流行(发病率低)环境中的性能,因为在目标从消除盘尾丝虫病这一公共卫生问题转变为消除(中断)传播(EOT)之前,这些诊断工具尚未被纳入大规模的 MDA 计划。2015年,在伊维菌素治疗前,我们在加蓬各地收集了14个区67个社区5829名参与者的年龄、性别和居住时间数据。其中4350人(75%)获得了皮吸样本(用于检测涡虫微丝蚴),4257人(98%)获得了血样(用于检测是否存在针对涡虫Ov16抗原的IgG4抗体)。对所有抽血者制备了干血斑 (DBS)。评估干血斑质量后,2990 份(70%)样本在实验室使用辣根过氧化物酶 (HRP) Ov16 酶联免疫吸附试验 (Ov16 ELISA) 进行了有效分析。不同诊断工具的阳性人数各不相同,皮片显微镜、Ov16 RDT 和 Ov16 酶联免疫吸附试验分别检测出 337/4,350 人(8 %,95 % CI =7 %-9%)、383/4,257 人(9 %,8 %-10%)和 348/2,990 人(12 %,10 %-13%)。这些数据对于政策制定者、检测试剂制造商和国家计划在社区层面确定是否适合使用 Ov16 RDT 进行划界绘图或评估社区或更广泛地说,评估单位在 EOT 路径上目前所处的阶段具有再利用的潜力。此外,这些数据对传播动力学建模者也很有用,他们可以根据这些数据拟合模型,以更好地了解在 Ov16 抗原存在的情况下,卷尾猴生命周期中可能导致 IgG4 抗体血清转换的阶段。这对于将抗体流行率作为盘尾丝虫病传播模型的输出结果至关重要,以便对目前提出的血清学阈值进行评估,从而在盘尾丝虫病消除绘图(OEM)和验证EOT的背景下分别为启动或停止MDA的决策提供信息。
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引用次数: 0
Building a benchmark dataset for the Kurdish news question answering 建立库尔德新闻问题解答基准数据集
IF 1 Q3 MULTIDISCIPLINARY SCIENCES Pub Date : 2024-09-06 DOI: 10.1016/j.dib.2024.110916

This article presents the Kurdish News Question Answering Dataset (KNQAD). The texts are collected from various Kurdish news websites. The ParsHub software is used to extract data from different fields of news, such as social news, religion, sports, science, and economy. The dataset consists of 15,002 news paragraphs with question-answer pairs. For each news paragraph, one or more question-answer pairs are manually created based on the content of the paragraphs. The dataset is pre-processed by cleaning and normalizing the data. During the cleaning process, special characters and stop words are removed, and stemming is used as a normalization step. The distribution of each question type is presented in the KNQAD. Moreover, the complexity of the QA problem is analyzed in the KNQAD by using lexical similarity techniques between questions and answers.

本文介绍库尔德新闻问题解答数据集(KNQAD)。这些文本是从多个库尔德新闻网站收集的。ParsHub 软件用于从社会新闻、宗教、体育、科学和经济等不同新闻领域提取数据。数据集由 15,002 个带有问答对的新闻段落组成。对于每个新闻段落,都会根据段落内容手动创建一个或多个问答对。数据集通过数据清理和归一化进行预处理。在清理过程中,特殊字符和停滞词会被删除,词干处理也会被用作归一化步骤。KNQAD 中显示了每种问题类型的分布情况。此外,KNQAD 还利用问题与答案之间的词法相似性技术分析了质量保证问题的复杂性。
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引用次数: 0
An integrated georeferenced dataset of public investments for soil defence in Italy 意大利土壤防护公共投资综合地理参考数据集
IF 1 Q3 MULTIDISCIPLINARY SCIENCES Pub Date : 2024-09-05 DOI: 10.1016/j.dib.2024.110909

The dataset collects and harmonizes financial data about public works in Italy, focusing on soil defence investments. The data are sourced from three distinct platforms: the Italian Ministry of Economics and Finance's open data platform OpenBDAP, the OpenCoesione website, concerned with interventions framed in cohesion policies financed by additional resources from the European and national budgets, and the ReNDiS database, provided by the Italian Institute for Environmental Protection and Research (ISPRA), that exclusively gathers information about public works in soil defence. The data records belonging to these three sources are linked by a unique project code (CUP), ensuring that there is no duplication of data. The OpenBDAP and OpenCoesione repositories report financial variables classified into various funds. In contrast, the ReNDiS database only provides the total amount of financial resources allocated to each intervention. Consequently, the merged dataset consolidates these financial variables into one, representing the total investment amount. For the first two databases this aggregate is derived by summing the financial flows from the different funds. Geographical referencing has been added to each intervention and each financial observation is associated with an Italian municipality. The database includes information on the region, province, and municipality for each record. Each database entry has also been equipped with the coordinates of the municipality's centroid and with the polygonal shape of the municipality area. Overall, the merged dataset encompasses 28 variables reporting three descriptive variables, one financial variable representing the total amount of financial resources, six geographic variables representing the codes and names of regions, provinces, and municipalities, sixteen variables referring to key dates of the process of public works, two geographical references variables respectively representing the centroids and the shape polygons of the municipality. This comprehensive dataset allows to analyse the spatial distribution of the resources allocated to soil defence investments. It offers insights to policymakers striving to allocate resources more efficiently, thereby fostering sustainable land management practices and ensuring the long-term health of the Italian ecosystems. The dataset can be complemented with additional information related to various concomitant aspects such as those pertaining to the environmental and socio-economic fields. This integration allows for broad analysis of the relationships between soil defence efforts and surrounding environmental and socio-economic contexts.

该数据集收集并统一了意大利公共工程的财务数据,重点关注土壤防御投资。数据来源于三个不同的平台:意大利经济和财政部的开放数据平台 OpenBDAP、OpenCoesione 网站(涉及由欧洲和国家预算额外资源资助的凝聚力政策框架内的干预措施),以及意大利环境保护和研究所(ISPRA)提供的 ReNDiS 数据库,该数据库专门收集有关土壤防护公共工程的信息。这三个来源的数据记录通过唯一的项目代码(CUP)进行链接,确保数据不会重复。OpenBDAP 和 OpenCoesione 数据库报告的财务变量分为不同的基金。相比之下,ReNDiS 数据库只提供分配给每项干预措施的资金总额。因此,合并后的数据集将这些财务变量合并为一个,代表投资总额。在前两个数据库中,这一总额是通过将不同基金的资金流相加得出的。每项干预措施都添加了地理参照,每项金融观察结果都与意大利的一个市镇相关联。数据库包括每个记录的地区、省和市的信息。每个数据库条目还配有该市的中心点坐标和该市区域的多边形。总体而言,合并后的数据集包含 28 个变量,其中 3 个是描述性变量,1 个是代表财政资源总额的财务变量,6 个是代表地区、省和市的代码和名称的地理变量,16 个是指公共工程进程中的关键日期的变量,2 个是分别代表市的中心点和多边形形状的地理参考变量。通过这一综合数据集,可以分析分配给土壤防护投资的资源的空间分布情况。它为政策制定者提供了见解,使其努力更有效地分配资源,从而促进可持续的土地管理实践,确保意大利生态系统的长期健康。该数据集还可补充与环境和社会经济领域等相关方面有关的其他信息。通过这种整合,可以对土壤防护工作与周围环境和社会经济背景之间的关系进行广泛分析。
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引用次数: 0
Flow field data of three-dimensional Riemann problems 三维黎曼问题的流场数据
IF 1 Q3 MULTIDISCIPLINARY SCIENCES Pub Date : 2024-09-05 DOI: 10.1016/j.dib.2024.110888

Common validation and verification test cases for compressible flow solvers are only one- or two-dimensional. Such flows, however, are inherently three-dimensional. The provided data contains simulation results of genuine three-dimensional Riemann problems computed with the open-source compressible flow solver ALPACA. The problems are designed so that each octant's constant initial state connects two neighboring states by only one elementary wave each. Thereby, initial conditions are chosen to induce three-dimensional effects. Furthermore, the cases are designed to trigger common shortcomings of compressible flow solvers, such as spurious pressure oscillations, unphysical symmetry breaking, or the onset of shock disturbances. The cases were simulated using a finite-volume scheme with HLLC and Roe Riemann solvers and fifth-order WENO reconstruction. The simulations were conducted on over 300 cores of a compute cluster. Besides the raw binary flow field data, input files are provided next to post-processing scripts and the visualizations obtained by them. The provided files ease setting up and simulating the respective cases with different solvers and allow quantitative comparisons of the obtained results.

可压缩流求解器的常见验证和核查测试案例只有一维或二维。然而,这种流动本质上是三维的。所提供的数据包含使用开源可压缩流求解器 ALPACA 计算的真正三维黎曼问题的模拟结果。问题的设计使每个八分之一的恒定初始状态只通过一个基本波连接两个相邻状态。因此,初始条件的选择可产生三维效应。此外,还设计了一些案例来触发可压缩流动求解器的常见缺陷,如假压力振荡、非物理对称性破坏或冲击扰动的发生。这些案例是使用带有 HLLC 和 Roe Riemann 求解器以及五阶 WENO 重建的有限体积方案进行模拟的。模拟在一个计算集群的 300 多个内核上进行。除了原始二进制流场数据外,还提供了输入文件、后处理脚本和可视化效果。所提供的文件便于使用不同的求解器设置和模拟相应的情况,并可对所获得的结果进行定量比较。
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引用次数: 0
LC-MS/MS-QTOF dataset of chemical compounds detected in honey samples from Bali and Lombok, Indonesia 印度尼西亚巴厘岛和龙目岛蜂蜜样品中检测到的化合物的 LC-MS/MS-QTOF 数据集
IF 1 Q3 MULTIDISCIPLINARY SCIENCES Pub Date : 2024-09-05 DOI: 10.1016/j.dib.2024.110884

Honey production is susceptible to manipulation by unscrupulous sellers, making honey authentication crucial to prevent fraud. The process of authenticating honey often necessitates the use of various analytical techniques, such as identifying the chemicals present in honey by means of hyphenated mass spectrometry. Here, we report on the investigation of the chemical composition of three honey samples collected at two locations in Lombok and Bali by liquid chromatography mass spectrometry (LC-MS). The three datasets include information regarding compound name, mass, retention times, as well as findings from database searches. Collectively, these data afford first insights into the compositional profile of honey samples from this specific geographical area.

蜂蜜的生产很容易受到不法销售商的操纵,因此,蜂蜜鉴定对于防止欺诈至关重要。在鉴定蜂蜜真伪的过程中,往往需要使用各种分析技术,例如通过联用质谱法鉴定蜂蜜中的化学成分。在此,我们报告了通过液相色谱质谱法(LC-MS)对龙目岛和巴厘岛两地采集的三种蜂蜜样本的化学成分进行调查的结果。这三个数据集包括化合物名称、质量、保留时间以及数据库搜索结果等信息。总体而言,这些数据首次揭示了这一特定地理区域蜂蜜样本的成分概况。
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引用次数: 0
Dataset for image classification with knowledge 知识图像分类数据集
IF 1 Q3 MULTIDISCIPLINARY SCIENCES Pub Date : 2024-09-05 DOI: 10.1016/j.dib.2024.110893

Deep learning applied to raw data has demonstrated outstanding image classification performance, mainly when abundant data is available. However, performance significantly degrades when a substantial volume of data is unavailable. Furthermore, deep architectures struggle to achieve satisfactory performance levels when distinguishing between distinct classes, such as fine-grained image classification, is challenging. Utilizing a priori knowledge alongside raw data can enhance image classification in demanding scenarios. Nevertheless, only a limited number of image classification datasets given with a priori knowledge are currently available, thereby restricting research efforts in this field. This paper introduces innovative datasets for the classification problem that integrate a priori knowledge. These datasets are built from existing data typically employed for multilabel multiclass classification or object detection. Frequent closed itemset mining is used to create classes and their corresponding attributes (e.g. the presence of an object in an image) and then to extract a priori knowledge expressed by rules on these attributes. The algorithm for generating rules is described.

应用于原始数据的深度学习已显示出出色的图像分类性能,主要是在有大量数据可用的情况下。然而,当大量数据不可用时,性能就会明显下降。此外,当区分不同类别(如细粒度图像分类)具有挑战性时,深度架构也很难达到令人满意的性能水平。在要求苛刻的情况下,利用先验知识和原始数据可以增强图像分类能力。然而,目前利用先验知识给出的图像分类数据集数量有限,从而限制了这一领域的研究工作。本文针对分类问题引入了集成先验知识的创新数据集。这些数据集由现有数据构建而成,通常用于多标签多类分类或物体检测。频繁封闭项集挖掘用于创建类别及其相应的属性(如图像中是否存在物体),然后通过这些属性的规则提取先验知识。本文介绍了生成规则的算法。
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引用次数: 0
Genome sequence data of Caudoviricetes bacteriophage MK21 infecting Xanthomonas citri, the causative agent of citrus canker 感染柑橘腐烂病病原体柑橘黄单胞菌的噬菌体 Caudoviricetes MK21 的基因组序列数据
IF 1 Q3 MULTIDISCIPLINARY SCIENCES Pub Date : 2024-09-05 DOI: 10.1016/j.dib.2024.110897

This dataset reports the isolation and genomic characterization of the Caudoviricetes bacteriophage MK21, a novel bacteriophage infecting Xanthomonas citri subsp. citri (XCC), collected from soil samples on Jeju Island, South Korea. The phage was isolated and enriched using double agar layer plaque assays on nutrient media. Genomic analysis revealed that the phage MK21 is a double-stranded circular DNA genome of 43,495 bp, comprising 61 genes with high coding density. The dataset includes detailed genomic information, highlighting genes related to structural components, lysis mechanisms, and DNA/RNA metabolism. Phylogenetic analysis shows a close relationship with Xanthomonas phage CP1, supporting its potential use in comparative genomic studies and the development of antibacterial agents against citrus canker. This dataset offers valuable insights for the advancement of phage therapy and sustainable agricultural practices.

本数据集报告了从韩国济州岛土壤样本中采集到的噬菌体 MK21 的分离和基因组特征,这是一种感染柠檬黄单胞菌亚种(XCC)的新型噬菌体。该噬菌体通过营养培养基上的双琼脂层斑块试验进行了分离和富集。基因组分析表明,噬菌体 MK21 是一个双链环状 DNA 基因组,长度为 43,495 bp,由 61 个高编码密度的基因组成。数据集包括详细的基因组信息,突出了与结构成分、裂解机制和 DNA/RNA 代谢有关的基因。系统发育分析表明,该噬菌体与黄单胞菌噬菌体 CP1 关系密切,支持将其用于比较基因组研究和柑橘腐烂病抗菌剂的开发。该数据集为推动噬菌体疗法和可持续农业实践提供了宝贵的见解。
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引用次数: 0
Data of crystal structure of the monomeric red fluorescent protein DsRed 单体红色荧光蛋白 DsRed 的晶体结构数据
IF 1 Q3 MULTIDISCIPLINARY SCIENCES Pub Date : 2024-09-05 DOI: 10.1016/j.dib.2024.110905
The monomeric red fluorescent protein DsRed (mDsRed) is an optical probe widely used in multicolor applications in flow cytometry and fluorescence microscopy. Although the crystal structure of monomeric DsRed has been determined, its molecular dynamics have not been fully elucidated. To better understand its molecular flexibility, the crystal structure of mDsRed was recently determined, and its structure and temperature factors were analyzed. Solvent-accessible hole connected with the mDsRed chromophore was observed on the mDsRed surface structure. Electron density map analysis showed the tyrosine-ring group of the mDsRed chromophore in a cis-conformation, exhibiting flexibility with a nonplanar configuration between the tyrosine and imidazoline rings of the chromophore. Temperature factor analysis indicated that the top and bottom of the β-barrel are relatively flexible. These structural findings extended our understanding of the molecular flexibility of mDsRed. The detailed data collection and structure determination reported in this study can be used for future structural analyses.
单体红色荧光蛋白 DsRed(mDsRed)是一种光学探针,广泛应用于流式细胞仪和荧光显微镜中的多色应用。虽然 DsRed 单体的晶体结构已经确定,但其分子动力学尚未完全阐明。为了更好地了解其分子灵活性,最近测定了 mDsRed 的晶体结构,并对其结构和温度因素进行了分析。在 mDsRed 表面结构上观察到了与 mDsRed 发色团相连的可溶解孔。电子密度图分析表明,mDsRed 发色团的酪氨酸环基团呈顺式构象,在发色团的酪氨酸环和咪唑啉环之间呈现出非平面构型的柔性。温度因素分析表明,β 管的顶部和底部相对灵活。这些结构发现扩展了我们对 mDsRed 分子柔性的理解。本研究中报告的详细数据收集和结构测定可用于未来的结构分析。
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引用次数: 0
Intestinal microbial profiles of wild Alaskan rainbow trout (Oncorhynchus mykiss) characterized by 16S rRNA amplicon data 用 16S rRNA 扩增子数据描述阿拉斯加野生虹鳟鱼(Oncorhynchus mykiss)的肠道微生物特征
IF 1 Q3 MULTIDISCIPLINARY SCIENCES Pub Date : 2024-09-05 DOI: 10.1016/j.dib.2024.110902

Rainbow trout (Oncorhynchus mykiss) is a dominant aquaculture species of the Salmonidae family, native only to the North Pacific. Recently, the gut microbiome has been shown to reflect the health status and responses to environmental changes in farmed fish. In this analysis we investigated the microbiome composition of the intestinal tract in 20 wild-caught rainbow trout specimens sampled in Alaska, USA. The targeted 16S rRNA gene (V3-V4 region) was sequenced on the Illumina NovaSeq 6000 platform. After quality control, demultiplexing and adapter trimming reads were analyzed using the DADA2 pipeline to obtain Amplicon Sequencing Variants (ASVs) which were subsequently taxonomically assigned. We found two phyla dominating the gut ecosystem present in every sample, Firmicutes and Fusobacteria, followed by lower abundances of Cyanobacteria, Proteobacteria and Bacteroidetes. At the genus level, we found high relative abundances of Cetobacterium and Clostridium sensu stricto 1. Interestingly, we did not identify often dominant genera Mycoplasma, Pseudomonas or Weisella which were prevalent in numerous studies previously, in cultured rainbow trout. Wild fish are exposed to a plethora of unpredictable environmental challenges, ranging from fluctuating water temperatures to variable food availability, as opposed to controlled conditions in production facilities. Examining and comparing the gut ecosystem of wild and reared individuals holds great potential in optimizing management practices for commercially important species. Microbiome studies can provide novel ways to enhance the overall welfare of fish, strengthen disease prevention and increase sustainability in aquaculture production.

虹鳟鱼(Oncorhynchus mykiss)是鲑科鱼类中的主要水产养殖品种,仅产于北太平洋。最近的研究表明,肠道微生物组能反映养殖鱼类的健康状况和对环境变化的反应。在这项分析中,我们调查了在美国阿拉斯加采样的 20 种野生虹鳟鱼标本的肠道微生物组组成。在 Illumina NovaSeq 6000 平台上对目标 16S rRNA 基因(V3-V4 区域)进行了测序。经过质量控制、解复用和适配器修剪后,使用 DADA2 管道对读数进行分析,以获得扩增子测序变异(ASVs),随后对其进行分类学分配。我们发现,在每个样本中都有两个门类在肠道生态系统中占主导地位,即固缩菌和镰刀菌,其次是含量较低的蓝藻、变形菌和类杆菌。有趣的是,我们并没有发现支原体、假单胞菌或魏氏菌等在养殖虹鳟中经常占主导地位的菌属,而这些菌属在以前的许多研究中都很普遍。与生产设施中的受控条件相比,野生鱼类面临着大量不可预测的环境挑战,从水温波动到食物可获得性的变化。研究和比较野生个体和饲养个体的肠道生态系统,对于优化重要商业物种的管理方法具有巨大潜力。微生物组研究可为提高鱼类的整体福利、加强疾病预防和提高水产养殖生产的可持续性提供新的方法。
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引用次数: 0
Dataset on factors influencing pedestrian crosswalk usage behavior in high-density urban areas of a developing country 发展中国家高密度城市地区影响行人使用人行横道行为的因素数据集
IF 1 Q3 MULTIDISCIPLINARY SCIENCES Pub Date : 2024-09-04 DOI: 10.1016/j.dib.2024.110912

The dataset consists of survey data on pedestrian crosswalk usage behavior in high-density urban areas of a developing country, specifically collected from Dhaka, the capital city of Bangladesh. Data were gathered through a questionnaire survey conducted at twelve key locations, covering eight attributes related to crosswalk behavior and the demographic details of respondents. The survey yielded 682 valid responses, focusing on factors such as the suitability of crosswalk locations, guard rails, and lighting. The dataset is structured to support analyses using supervised machine learning techniques, facilitating reproducibility, secondary analysis, and policy development for pedestrian safety improvements. Furthermore, the dataset can be reused for cross-validation of future studies, comparison with pedestrian behavior in similar urban settings, and the development of predictive models to enhance pedestrian infrastructure in other developing regions.

数据集包括发展中国家高密度城市地区行人使用人行横道行为的调查数据,特别是从孟加拉国首都达卡收集的数据。数据是通过在 12 个主要地点进行的问卷调查收集的,涉及与人行横道行为相关的 8 个属性和受访者的人口统计学细节。调查共收到 682 份有效回复,主要涉及人行横道位置的适宜性、护栏和照明等因素。该数据集的结构支持使用有监督的机器学习技术进行分析,有利于可重复性、二次分析和行人安全改进政策的制定。此外,该数据集还可重复用于未来研究的交叉验证、与类似城市环境中行人行为的比较,以及开发预测模型,以改善其他发展中地区的行人基础设施。
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引用次数: 0
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