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New future dental material: Antimicrobial material "cetylpyridinium chloride-montmorillonite" and implantable material "phosphorylated pullulan". 未来新型牙科材料:抗菌材料“十六烷基氯代吡啶蒙脱土”和植入式材料“磷酸化普鲁兰”。
IF 1.9 4区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-01-31 Epub Date: 2025-01-11 DOI: 10.4012/dmj.2024-243
Ko Nakanishi, Tsukasa Akasaka, Yasuhiko Abe, Hiroshi Hayashi, Kumiko Yoshihara, Teppei Nakamura, Mariko Nakamura, Bart Van Meerbeek, Yasuhiro Yoshida

In dental practice, there are two major diseases: dental caries and periodontal disease. Although dental treatment techniques have advanced along with advances in dental materials, some diseases such as root surface caries and horizontal bone resorption have not yet achieved satisfactory treatment results. Since these diseases are infections caused by oral bacteria, we believe that materials with long-lasting antimicrobial properties would help control these diseases. In addition, materials that can adhere to wet hard tissues would contribute to treatment. In this review, new materials developed based on this idea, the antimicrobial material "cetylpyridinium chloride-montmorillonite" and the hard tissue adhesive implantable material "phosphorylated pullulan" was introduced.

在牙科实践中,有两种主要疾病:龋齿和牙周病。虽然牙科治疗技术随着牙科材料的进步而进步,但一些疾病如根面龋病、水平骨吸收等的治疗效果仍不理想。由于这些疾病是由口腔细菌引起的感染,我们相信具有持久抗菌性能的材料将有助于控制这些疾病。此外,能够粘附在湿硬组织上的材料也有助于治疗。本文介绍了基于这一思路开发的新型材料,抗菌材料“十六烷基吡啶氯化蒙脱土”和硬质组织粘连植入材料“磷酸化普鲁兰”。
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引用次数: 0
Preparation of CMC/ACP/PHMB nanocomposites and preliminary study on their antibacterial and remineralization functions. CMC/ACP/PHMB纳米复合材料的制备及其抗菌和再矿化功能的初步研究。
IF 1.9 4区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-01-31 Epub Date: 2024-12-07 DOI: 10.4012/dmj.2024-184
Honglei Guo, Ning Wang, Xuan Ye, Xinye Zhou, Kai Zhang, Xu Zhang

Caries is a chronic oral disease causing a series of complications. This study aims to develop a material that could remineralize demineralized enamel and simultaneously exert antibacterial effects. A carboxymethyl chitosan (CMC)/amorphous calcium phosphate (ACP)/polyhexamethylene biguanide hydrochloride (PHMB) nanocomposite was synthesized for the first time, and its stability, remineralization ability, and antibacterial properties were investigated in this study. PHMB has excellent antibacterial properties, was used as an additive to stabilize ACP. The enamel surface covered with CMC/ACP/PHMB showed a uniform layer with a similar elemental ratio to that of natural hydroxyapatite and the ratio of crystal diffraction peaks was close to that of natural enamel. The mechanical properties, including hardness and elastic modulus, of the enamel in all experimental groups were restored. The antibacterial effect of 240 mg/L CMC/ACP/PHMB was comparable to that of 0.12% CMC/ACP/chlorhexidine. This study provides a theoretical and experimental basis for the development of novel dual-function anticaries agent.

龋齿是一种引起一系列并发症的慢性口腔疾病。本研究旨在开发一种既能使脱矿牙釉质再矿化,又能发挥抗菌作用的材料。首次合成了羧甲基壳聚糖(CMC)/无定形磷酸钙(ACP)/聚六亚甲基双胍盐酸盐(PHMB)纳米复合材料,并对其稳定性、再矿化能力和抗菌性能进行了研究。PHMB具有优良的抗菌性能,被用作稳定ACP的添加剂。CMC/ACP/PHMB覆盖的牙釉质表面呈均匀层状,元素比与天然羟基磷灰石相似,晶体衍射峰比与天然牙釉质相近。各实验组牙釉质硬度、弹性模量等力学性能均恢复正常。240 mg/L CMC/ACP/PHMB的抑菌效果与0.12% CMC/ACP/氯己定相当。本研究为开发新型双功能抗菌剂提供了理论和实验依据。
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引用次数: 0
Evaluation with finite element analysis of a ball attachment overdenture prosthesis of a patient. 用有限元分析评价患者的球形附着覆盖义齿修复。
IF 1.9 4区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-01-31 Epub Date: 2024-12-21 DOI: 10.4012/dmj.2024-252
Hatice Özdemir, Burak Hülagü

This study aimed to apply finite element analysis (FEA) to simulate the oral environment of a patient with an implant-supported overdenture prosthesis. A 3D mandibular model was created for a 45-year-old female patient from CT images, with mucosal thickness measured at 3 mm on average using ultrasonography. The overdenture prosthesis was scanned with an intraoral scanner and placed onto the 3D mandibular model. Displacement of the prosthesis and von Mises stress values of the implant, surrounding bone tissue, implant-prosthesis components, and mucosa were calculated under various masticatory loads. The study found that anterior mastication generated higher stress compared to unilateral and bilateral mastication. The addition of a third implant significantly reduced stress and improved prosthesis stability, particularly during bilateral mastication.

本研究旨在应用有限元分析(FEA)模拟种植覆盖义齿患者的口腔环境。本文以45岁女性患者为研究对象,根据CT图像建立下颌三维模型,超声测量其黏膜厚度平均为3mm。用口腔内扫描仪扫描复盖义齿,并将复盖义齿置于三维下颌模型上。计算不同咀嚼负荷下假体的位移和种植体、周围骨组织、种植体-假体构件和黏膜的von Mises应力值。研究发现,与单侧和双侧咀嚼相比,前咀嚼产生的压力更大。添加第三个种植体可显著减少压力并改善假体稳定性,特别是在双侧咀嚼时。
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引用次数: 0
Bond strength of self-adhesive resin cement to definitive resin crown materials manufactured by additive and subtractive methods. 自粘树脂水泥与用增减法制造的确定树脂冠材料的粘结强度。
IF 1.9 4区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-01-31 Epub Date: 2024-12-07 DOI: 10.4012/dmj.2024-111
Elifnaz Ozen Sutuven, Nuray Capa Yildirim

The aim was to compare different surface pretreatments on definitive resin crown materials manufactured additively or subtractively in terms of shear bond strength (SBS) values. Seven subgroups (n=10) were formed from additively manufactured VarseoSmile Crown Plus (VS) and subtractively manufactured Cerasmart270 blocks (CS) according to different surface pretreatments applied; sandblasting (subgroup SB), hydrofluoric acid (subgroup HF), Multi Primer (subgroup MP), subgroup SB-HF, subgroup SB-MP, subgroup SB-HF-MP, and control subgroup. A 3-mm-diameter composite was cemented onto each sample by self-adhesive resin cement. SBS values were measured and failure modes were analyzed after thermocycling. Data were analyzed with two-way ANOVA and Tukey HSD tests. The mean SBS value of VS was found significantly higher than CS (p<0.001). Subgroups SB-HF-MP, HF, SB-MP, and MP of VS exhibited the highest SBS values (p<0.001). The VS exhibited mostly cohesive failure, while CS exhibited mostly adhesive failure.

目的是比较不同的表面预处理对确定树脂冠材料的添加或减法制造的剪切粘接强度(SBS)值。根据不同的表面预处理,将增材制造的VarseoSmile Crown Plus (VS)和减材制造的Cerasmart270 block (CS)组成7个亚组(n=10);喷砂(SB亚组)、氢氟酸(HF亚组)、多引物(MP亚组)、SB-HF亚组、SB-MP亚组、SB-HF-MP亚组和对照亚组。用自粘树脂水泥将直径为3mm的复合材料粘接在每个样品上。测量了SBS值,分析了热循环后的失效模式。数据分析采用双因素方差分析和Tukey HSD检验。VS的平均SBS值显著高于CS (p
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引用次数: 0
The influence of phosphoric acid and primer treatment on the evaluation of the adhesive resin cement/enamel interface. 磷酸和底漆处理对胶粘剂树脂水泥/牙釉质界面评价的影响。
IF 1.9 4区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-01-31 Epub Date: 2024-12-03 DOI: 10.4012/dmj.2024-214
Mengtian Zhao, Takaaki Sato, Abu Hasan Mohammad Khaled, Masaomi Ikeda, Yasushi Shimada

This study evaluated the influence of phosphoric acid and primer on enamel bonding performance using Panavia V5. Ground bovine enamels were assigned: using K-etchant syringe and Tooth Primer (CT), using K-etchant syringe (PA), using Tooth Primer (TP), neither K-etchant syringe nor Tooth Primer was used (NC). The micro-tensile bond strength values of CT and PA were significantly higher than TP. After thermal cycling, the values were higher in CT and PA. In the leakage test, line-shaped signal pattern at the adhesive interface was detected in NC, and the signal was partially detected in PA and TP. Observation of the adhesive interface after acid and base challenge confirmed tooth-like structures in groups except NC. Large spaces were observed between the enamel and cement in NC. Limited in this study, the lack of application of phosphoric acid or Tooth Primer may affect the enamel bonding performance.

以Panavia V5为材料,研究了磷酸和底漆对釉质粘接性能的影响。磨碎的牛牙釉质分配:使用k -蚀刻注射器和牙底漆(CT),使用k -蚀刻注射器(PA),使用牙底漆(TP),不使用k -蚀刻注射器和牙底漆(NC)。CT和PA的微拉伸粘结强度值明显高于TP。热循环后,CT和PA值升高。在泄漏试验中,NC在粘接界面处检测到线状信号模式,PA和TP检测到部分信号。酸、碱激发后的粘接界面观察证实除NC组外其余各组均有齿状结构。NC牙釉质与骨水泥间空隙较大。在本研究中,缺乏磷酸或牙底漆的应用可能会影响牙釉质的粘接性能。
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引用次数: 0
Evaluation of resorption rate-controlled calcium carbonate ceramics as a substitute bone material. 可控制吸收速率的碳酸钙陶瓷替代骨材料的评价。
IF 1.9 4区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-01-31 Epub Date: 2024-12-28 DOI: 10.4012/dmj.2024-120
Shota Umemoto, Toshitake Furusawa, Hidero Unuma, Tomoyo Goto, Tohru Sekino

Artificial bone, primarily composed of calcium carbonate, demonstrates a higher resorption rate than calcium phosphate-based counterparts, suggesting potential for early bone replacement. Animal experiments using porous calcium carbonate ceramics have demonstrated bone formation superior to commercially available artificial bone after short-term implantation. Long-term implantation has yielded suboptimal results owing to resorption of both newly formed bone and implantation material. We prepared calcium carbonate ceramics added with silica (Si-CaCO3) to regulate the resorption rate. After 12 weeks of implantation, Si-CaCO3 ceramics exhibited bone formation comparable to that of β-tricalcium phosphate (β-TCP) but less variability in the distribution of bone formation within the tissue. An in vitro dissolution test, serving as an indicator of in vivo resorption rate, revealed that Si-CaCO3 ceramics exhibited an intermediate dissolution rate between high-purity calcium carbonate and β-TCP ceramics. Silica doping in CaCO3 ceramics presents an effective approach for aligning material resorption with bone formation and growth.

人工骨主要由碳酸钙组成,其吸收率高于以磷酸钙为基础的人工骨,这表明早期骨置换的潜力。使用多孔碳酸钙陶瓷的动物实验表明,短期植入后骨形成优于市售人工骨。由于新形成的骨和植入材料的重新吸收,长期植入产生了不理想的结果。我们制备了添加二氧化硅(Si-CaCO3)的碳酸钙陶瓷,以调节吸收率。植入12周后,Si-CaCO3陶瓷的骨形成与β-磷酸三钙(β-TCP)相当,但骨形成在组织内分布的可变性较小。体外溶出试验表明,Si-CaCO3陶瓷的溶出速率介于高纯碳酸钙和β-TCP陶瓷之间。二氧化硅掺杂CaCO3陶瓷是一种将材料吸收与骨形成和生长结合起来的有效方法。
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引用次数: 0
Evaluation of mechanical properties and ion-releasing of 3D printing resins containing S-PRG filler: A preliminary study. 含S-PRG填料的3D打印树脂的力学性能和离子释放评价:初步研究。
IF 1.9 4区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-01-31 Epub Date: 2024-12-03 DOI: 10.4012/dmj.2024-195
Yukiko Tsuji, Noriko Hiraishi, Masaomi Ikeda, Motohiro Uo, Yumi Tsuchida, Kei Ushijima, Toru Nikaido, Yasushi Shimada

This study aimed to evaluate ionic release, flexural strength and water absorption of UDMA resins containing 0-30 wt% surface pre-reacted glass-ionomer (S-PRG) filler fabricated by a DLP 3D printer. Release of Al, B, Na, Sr and F ions were measured by inductively coupled plasma (ICP) and an ion meter. Flexural strength test and water absorption measurements were performed according to the International Organization for Standardization (ISO) 4049 standard and ISO 1567 standard, respectively. Sr ions were released the most, followed by F, B, Na and Al ions. The highest flexural strength was recorded with the S-PRG filler amount 0 wt%, followed by the S-PRG filler amounts 30, 20 and 10 wt%. Water absorption after one week was below the 32 µg/mm3 mark specified by ISO 1567. The release of ions was confirmed using UDMA-based photopolymerized resin containing S-PRG filler. Furthermore, the results suggest that this resin could be used for provisional restoration.

本研究旨在评估DLP 3D打印机制备的含有0-30 wt%表面预反应玻璃离子聚体(S-PRG)填料的UDMA树脂的离子释放、弯曲强度和吸水率。用电感耦合等离子体(ICP)和离子计测量Al、B、Na、Sr和F离子的释放。抗弯强度测试和吸水率测试分别按照国际标准化组织(ISO) 4049标准和ISO 1567标准进行。Sr离子释放最多,其次是F、B、Na和Al离子。当S-PRG填充量为0 wt%时,其抗折强度最高,其次为30 wt%、20 wt%和10 wt%。一周后的吸水率低于ISO 1567规定的32µg/mm3。用含S-PRG填料的udma基光聚合树脂对离子的释放进行了验证。此外,研究结果表明,该树脂可用于临时修复。
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引用次数: 0
Inhibitory effects of Colocasia antiquorum var. esculenta varnish on inflammation and alveolar bone loss in a rat ligature-induced periodontitis model. 在大鼠结扎性牙周炎模型中,牙槽骨清漆对炎症和牙槽骨丢失的抑制作用。
IF 1.9 4区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-01-31 Epub Date: 2024-12-28 DOI: 10.4012/dmj.2024-180
Seong-Hee Moon, Seong-Jin Shin, Gyu-Yeon Shim, Hyun-Jin Kim, Seunghan Oh, Seong-Hwan Kim, Ji-Myung Bae

We aimed to evaluate whether Colocasia antiquorum var. esculenta (CA) mixed with experimental varnish inhibits inflammation and alveolar bone loss in a rat ligature-induced periodontitis model. The minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) were tested and cell viability of CA were also evaluated. The varnish mixed with CA (CAV) was applied to ligature site of Sprague-Dawley rats and alveolar bone loss and cytokines were measured. CA exhibited a MIC of 31.3 μg/mL and an MBC of 62.5 μg/mL against Porphyromonas gingivalis, with no cytotoxicity. The CAV group exhibited significantly lower levels of alveolar bone loss than the PC group (p<0.05). The expression of IL-1β, TNF-α, and IL-6 was significantly decreased, while that of Runx2 was significantly increased in the CAV than in the PC group (p<0.05). In conclusion, CAV demonstrated the potential to improve the symptoms of periodontitis.

我们的目的是评估在大鼠结扎诱导的牙周炎模型中,与实验用清漆混合的芋头(CA)是否能抑制炎症和牙槽骨流失。测试了最低抑菌浓度(MIC)和最低杀菌浓度(MBC),还评估了 CA 的细胞活力。将与 CA 混合的清漆(CAV)涂抹在 Sprague-Dawley 大鼠的结扎部位,测量牙槽骨损失和细胞因子。CA 对牙龈卟啉单胞菌的 MIC 为 31.3 μg/mL,MBC 为 62.5 μg/mL,无细胞毒性。CAV 组的牙槽骨损失水平明显低于 PC 组(p
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引用次数: 0
Erratum to: Osteoinductivity performance dicalcium phosphate dihydrate-coated porous β-tricalcium phosphate granules in adipose-derived mesenchymal stem cells. 二水磷酸二钙包被多孔β-磷酸三钙颗粒在脂肪源间充质干细胞中的骨诱导性能。
IF 1.9 4区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-01-01 DOI: 10.4012/dmj.2024-310-e
Khairul Anuar Shariff, Alexander Patera Nugraha, Ahmed Hafedh Mohammed Mohammed, Ida Bagus Narmada, I Gusti Aju Wahju Ardani, Nastiti Faradilla Ramadhani, Ratri Maya Sitalaksmi, Wibi Riawan, Helen Susilowati, Suryo Kuncorojakti, Bramasta Nugraha, Guang Hong
{"title":"Erratum to: Osteoinductivity performance dicalcium phosphate dihydrate-coated porous β-tricalcium phosphate granules in adipose-derived mesenchymal stem cells.","authors":"Khairul Anuar Shariff, Alexander Patera Nugraha, Ahmed Hafedh Mohammed Mohammed, Ida Bagus Narmada, I Gusti Aju Wahju Ardani, Nastiti Faradilla Ramadhani, Ratri Maya Sitalaksmi, Wibi Riawan, Helen Susilowati, Suryo Kuncorojakti, Bramasta Nugraha, Guang Hong","doi":"10.4012/dmj.2024-310-e","DOIUrl":"https://doi.org/10.4012/dmj.2024-310-e","url":null,"abstract":"","PeriodicalId":11065,"journal":{"name":"Dental materials journal","volume":"44 6","pages":"716"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145647781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A new method to measure the mechanical properties of rotary endodontic Ni-Ti files: Measurement of 6-axis force/torque and automatic root canal preparation. 测量旋转根管治疗镍钛锉机械性能的新方法:测量六轴力/扭矩和自动根管预备。
IF 1.9 4区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-12-10 Epub Date: 2024-10-02 DOI: 10.4012/dmj.2024-082
Hyungwoo Lee, In-Bog Lee

The purpose of this study was to develop a new instrument to measure the mechanical properties of rotary endodontic Ni-Ti files (ProTaper Gold F2, ProTaper Ultimate F2, and HyFlex EDM Onefile), and to evaluate the overall utility of the device. The instrument was capable of analyzing the 6-axis force/torque generated by the files during cyclic dynamic movement in a metal curved artificial root canal, and doing automatic cyclic dynamic filing in a resin root canal with a preset vertical force limit by adopting a negative feedback mechanism. By analyzing the 6-axis force/torque, we were able to estimate the position and contact points of the files in the curved root canal. ProTaper Gold showed the highest force/torque in all directions. HyFlex EDM had the highest hysteresis ratio, centering ratio value and NCF (number of cycles to fatigue fracture), while the lowest vertical force.

本研究的目的是开发一种新仪器,用于测量旋转式根管治疗镍钛锉(ProTaper Gold F2、ProTaper Ultimate F2 和 HyFlex EDM Onefile)的机械性能,并评估该设备的整体效用。该仪器能够分析锉在金属弯曲人工根管中循环动态运动时产生的六轴力/扭矩,并通过采用负反馈机制,在预设垂直力限制的树脂根管中进行自动循环动态锉磨。通过分析六轴力/力矩,我们可以估算出锉刀在弯曲根管内的位置和接触点。ProTaper Gold 在所有方向上都显示出最高的力/扭矩。HyFlex EDM 的滞后比、中心比值和 NCF(疲劳断裂循环次数)最高,而垂直力最低。
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引用次数: 0
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Dental materials journal
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