Enfermedades infecciosas y microbiologia clinica最新文献

英文中文

Impacto de una intervención PROA en la solicitud de urocultivos de control postratamiento en atención primaria PROA干预对初级保健中治疗后控制尿路培养需求的影响

IF 2.5 4区医学 Q3 INFECTIOUS DISEASES

Enfermedades infecciosas y microbiologia clinica

Pub Date : 2025-12-01 DOI: 10.1016/j.eimc.2025.06.018

Iker Alonso-González , Maider Zuriarrain-Alonso , Koldo López-Guridi , Paula Lara-Esbrí , Rita Sainz de Rozas , Itxasne Lekue , José Luis Barrios-Andrés

Introduction

With the aim of reducing the number of post-treatment control urine cultures (UC) from health centers in our healthcare area, we conducted an ASP intervention throughout 2022. To do this, we set out to introduce effective methods to quantify, analyze, and subsequently try to reduce the number of inappropiate UC.

Methods

We conducted a prospective and non-restrictive quasi-experimental intervention study with historical and parallel control group to evaluate the impact of the intervention. The UC evaluation was performed by analyzing all the medical records of repeated UC in a period of less than 31 days. UC were classified as: appropriate, inappropriate and doubtful. The study was conducted in 3 phases: phase 1) measurement of the baseline situation; phase 2) intervention in intervention group: simple educational presentations and implementation of a non-restrictive computerized rule, and phase 3) analysis of results in both groups and periods.

Results

Looking at the percentage of appropriate UC, we observed that in the control group there was hardly any variation while in the intervention group these increased by 152.4 (p < 0.001). In addition, in the intervention group there was a decrease in total UCs of 55.4% (n = 418), representing an estimated savings of €7524. The acceptance of the computerized rule in the intervention group was 9.6%.

Conclusions

This ASP intervention is useful in decreasing the number of IUCs, especially the educational presentations. Achieving this can reduce direct and indirect patient harm and healthcare overload, in addition to improving the management of healthcare resources.

前言：为了减少我们医疗保健地区卫生中心治疗后对照尿培养（UC）的数量，我们在2022年进行了ASP干预。为了做到这一点，我们开始引入有效的方法来量化、分析，并随后尝试减少不适当的UC的数量。方法采用前瞻性、非限制性准实验干预研究，采用历史对照组和平行对照组，评价干预效果。通过分析所有在31天以内重复UC的医疗记录进行UC评估。UC分为：适当、不适当和可疑。研究分三个阶段进行：第一阶段测量基线情况；第二阶段对干预组进行干预：简单的教育演示和非限制性计算机规则的实施，第三阶段对两组和两期的结果进行分析。结果观察适当UC的百分比，我们观察到在对照组中几乎没有任何变化，而在干预组中这些变化增加了152.4 （p < 0.001）。此外，在干预组中，总UCs减少了55.4% (n = 418)，估计节省了7524欧元。干预组对计算机化规则的接受度为9.6%。结论ASP干预可有效减少IUCs的数量，尤其是教育报告的数量。实现这一目标除了可以改善医疗资源管理外，还可以减少对患者的直接和间接伤害以及医疗保健超载。

{"title":"Impacto de una intervención PROA en la solicitud de urocultivos de control postratamiento en atención primaria","authors":"Iker Alonso-González , Maider Zuriarrain-Alonso , Koldo López-Guridi , Paula Lara-Esbrí , Rita Sainz de Rozas , Itxasne Lekue , José Luis Barrios-Andrés","doi":"10.1016/j.eimc.2025.06.018","DOIUrl":"10.1016/j.eimc.2025.06.018","url":null,"abstract":"<div><h3>Introduction</h3><div>With the aim of reducing the number of post-treatment control urine cultures (UC) from health centers in our healthcare area, we conducted an ASP intervention throughout 2022. To do this, we set out to introduce effective methods to quantify, analyze, and subsequently try to reduce the number of inappropiate UC.</div></div><div><h3>Methods</h3><div>We conducted a prospective and non-restrictive quasi-experimental intervention study with historical and parallel control group to evaluate the impact of the intervention. The UC evaluation was performed by analyzing all the medical records of repeated UC in a period of less than 31 days. UC were classified as: appropriate, inappropriate and doubtful. The study was conducted in 3 phases: phase 1) measurement of the baseline situation; phase 2) intervention in intervention group: simple educational presentations and implementation of a non-restrictive computerized rule, and phase 3) analysis of results in both groups and periods.</div></div><div><h3>Results</h3><div>Looking at the percentage of appropriate UC, we observed that in the control group there was hardly any variation while in the intervention group these increased by 152.4 (p<0.001). In addition, in the intervention group there was a decrease in total UCs of 55.4% (n=418), representing an estimated savings of €7524. The acceptance of the computerized rule in the intervention group was 9.6%.</div></div><div><h3>Conclusions</h3><div>This ASP intervention is useful in decreasing the number of IUCs, especially the educational presentations. Achieving this can reduce direct and indirect patient harm and healthcare overload, in addition to improving the management of healthcare resources.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 10","pages":"Pages 652-658"},"PeriodicalIF":2.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145645427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antimicrobial resistance patterns of Nocardia species in clinical isolates from Argentina (2020–2022) 阿根廷诺卡菌临床分离株耐药性分析（2020-2022年）

IF 2.5 4区医学 Q3 INFECTIOUS DISEASES

Enfermedades infecciosas y microbiologia clinica

Pub Date : 2025-12-01 DOI: 10.1016/j.eimc.2025.07.003

Mónica Prieto, María Florencia Rocca, Rita Armitano, Ariel Gianecini, Lucía Cipolla

Introduction

Nocardia species are opportunistic pathogens with intrinsic antimicrobial resistance and regional variability in susceptibility patterns. Argentina lacks standardized surveillance data, complicating empirical therapy. This study aimed to characterize Nocardia species distribution and antimicrobial resistance profiles nationwide.

Methods

We analyzed 62 clinical Nocardia isolates from 41 laboratories across eight Argentine provinces (2020–2022). Species identification utilized MALDI-TOF mass spectrometry. Antimicrobial susceptibility testing was performed via broth microdilution for 11 antibiotics according to CLSI guidelines, with additional E-test comparisons.

Results

Respiratory specimens predominated (67.7%), followed by central nervous system (14.5%), skin/soft tissue (8.1%), and bloodstream (6.5%) infections. Primary species identified were N. cyriacigeorgica (30.6%), N. abscessus complex (22.6%), and N. farcinica complex (17.7%). Highest susceptibility rates occurred with linezolid (100%) and trimethoprim–sulfamethoxazole (97.6%). Significant resistance was observed for clarithromycin (81.0%), ciprofloxacin (76.2%), and moxifloxacin (57.1%). N. farcinica dominated CNS infections (55.6%), while N. brasiliensis complex prevailed in skin/soft tissue cases (80%). Methodological discrepancies between testing methods showed 33.3% major errors for ceftriaxone (E-test vs. microdilution).

Conclusion

This first Argentine nationwide surveillance study confirms trimethoprim–sulfamethoxazole and linezolid as reliable empiric therapy options while highlighting concerning resistance to fluoroquinolones and macrolides. The observed methodological discordance emphasizes the critical need for standardized antimicrobial susceptibility testing protocols for Nocardia species.

诺卡菌属是条件致病菌，具有固有的抗菌素耐药性和药敏模式的区域差异。阿根廷缺乏标准化的监测数据，使经验性治疗复杂化。本研究旨在了解全国诺卡菌种类分布及耐药情况。方法对阿根廷8个省41个实验室的62株诺卡菌临床分离株（2020-2022年）进行分析。物种鉴定采用MALDI-TOF质谱法。根据CLSI指南，通过肉汤微量稀释对11种抗生素进行抗生素药敏试验，并进行e试验比较。结果呼吸道感染占67.7%，其次是中枢神经系统感染（14.5%）、皮肤/软组织感染（8.1%）和血液感染（6.5%）。主要种为cyriacigorgica（30.6%）、abesssus复合体（22.6%）和farcinica复合体（17.7%）。利奈唑胺（100%）和甲氧苄啶-磺胺甲恶唑（97.6%）的敏感性最高。克拉霉素（81.0%）、环丙沙星（76.2%）和莫西沙星（57.1%）耐药显著。中枢神经系统感染以法氏奈瑟菌为主（55.6%），皮肤/软组织感染以巴西奈瑟菌复体为主（80%）。不同检测方法之间的方法学差异显示头孢曲松的主要误差为33.3% （e试验与微量稀释试验）。结论阿根廷首次全国监测研究证实甲氧苄啶-磺胺甲恶唑和利奈唑胺是可靠的经验性治疗选择，同时强调对氟喹诺酮类药物和大环内酯类药物的耐药性。观察到的方法上的不一致强调了对诺卡菌种的标准化抗菌药物敏感性测试方案的迫切需要。

{"title":"Antimicrobial resistance patterns of Nocardia species in clinical isolates from Argentina (2020–2022)","authors":"Mónica Prieto, María Florencia Rocca, Rita Armitano, Ariel Gianecini, Lucía Cipolla","doi":"10.1016/j.eimc.2025.07.003","DOIUrl":"10.1016/j.eimc.2025.07.003","url":null,"abstract":"<div><h3>Introduction</h3><div><em>Nocardia</em> species are opportunistic pathogens with intrinsic antimicrobial resistance and regional variability in susceptibility patterns. Argentina lacks standardized surveillance data, complicating empirical therapy. This study aimed to characterize <em>Nocardia</em> species distribution and antimicrobial resistance profiles nationwide.</div></div><div><h3>Methods</h3><div>We analyzed 62 clinical <em>Nocardia</em> isolates from 41 laboratories across eight Argentine provinces (2020–2022). Species identification utilized MALDI-TOF mass spectrometry. Antimicrobial susceptibility testing was performed via broth microdilution for 11 antibiotics according to CLSI guidelines, with additional E-test comparisons.</div></div><div><h3>Results</h3><div>Respiratory specimens predominated (67.7%), followed by central nervous system (14.5%), skin/soft tissue (8.1%), and bloodstream (6.5%) infections. Primary species identified were <em>N. cyriacigeorgica</em> (30.6%), <em>N. abscessus</em> complex (22.6%), and <em>N. farcinica</em> complex (17.7%). Highest susceptibility rates occurred with linezolid (100%) and trimethoprim–sulfamethoxazole (97.6%). Significant resistance was observed for clarithromycin (81.0%), ciprofloxacin (76.2%), and moxifloxacin (57.1%). <em>N. farcinica</em> dominated CNS infections (55.6%), while <em>N. brasiliensis</em> complex prevailed in skin/soft tissue cases (80%). Methodological discrepancies between testing methods showed 33.3% major errors for ceftriaxone (E-test vs. microdilution).</div></div><div><h3>Conclusion</h3><div>This first Argentine nationwide surveillance study confirms trimethoprim–sulfamethoxazole and linezolid as reliable empiric therapy options while highlighting concerning resistance to fluoroquinolones and macrolides. The observed methodological discordance emphasizes the critical need for standardized antimicrobial susceptibility testing protocols for <em>Nocardia</em> species.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 10","pages":"Pages 659-665"},"PeriodicalIF":2.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145645428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Paciente con cuadro séptico, carcinoma urotelial y lesiones pulmonares 化粪池、输尿管癌和肺部病变患者

IF 2.5 4区医学 Q3 INFECTIOUS DISEASES

Enfermedades infecciosas y microbiologia clinica

Pub Date : 2025-11-01 DOI: 10.1016/j.eimc.2025.05.005

Mónica Pilar Ariza Samper , Sara Sanz Sanz , Desiré Gil Pérez , Jesús Viñuelas Bayón

引用次数: 0

Outbreak of Schistosomiasis mansoni in a Spanish dance and percussion ensemble acquired in the Republic of Guinea 在几内亚共和国获得的西班牙舞蹈和打击乐合奏团中爆发曼氏血吸虫病

IF 2.5 4区医学 Q3 INFECTIOUS DISEASES

Enfermedades infecciosas y microbiologia clinica

Pub Date : 2025-11-01 DOI: 10.1016/j.eimc.2025.01.012

Marta Arsuaga Vicente , Guillermo Ruiz-Carrascoso , Fernando De la Calle-Prieto , Javier Sotillo Gallego , Rosa De Miguel-Buckley , Mar Lago Nuñez , Daniel Mesado Martinez , Marta Díaz Menéndez

Introduction

Schistosomiasis is a neglected tropical disease endemic in 78 countries worldwide. The acute phase, commonly referred to as Katayama fever, is more frequently observed in travelers than in migrants. Despite significant progress in understanding its pathology, many aspects of this disease remain unclear, posing challenges to timely diagnosis and management.

Methods

This observational retrospective study was conducted at the National Referral Unit for Imported Tropical Diseases, located at Hospital La Paz-Carlos III in Madrid, Spain. The study included a total of 14 members of a dance and percussion ensemble that traveled to the Republic of Guinea from March 3 to March 18, 2023. Patients with confirmed or probable schistosomiasis were included in the analysis.

Results

Twelve patients had suspected acute schistosomiasis. Of these, 78.5% were female. The predominant clinical manifestations included fever (91.6%), eosinophilia (100%), acute diarrhea (91.6%), and abdominal pain (83.3%). All patients reported a history of freshwater exposure in Guinea. Schistosoma serology was positive in all cases, and stool samples from five patients revealed the presence of Schistosoma mansoni eggs. Acute symptoms were managed with corticosteroids, leading to clinical improvement in all cases. Thereafter, all patients were treated with praziquantel at a dose of 40 mg/kg/day, administered in two separate doses four weeks apart.

Conclusion

Freshwater exposure in tropical regions is the primary risk factor for acquiring schistosomiasis. Early diagnosis and treatment during the acute phase are crucial to prevent complications and long-term sequelae.

血吸虫病是一种被忽视的热带病，在全世界78个国家流行。急性期，通常称为片山热，在旅行者中比在移民中更常观察到。尽管在了解其病理方面取得了重大进展，但这种疾病的许多方面仍不清楚，对及时诊断和管理提出了挑战。方法本观察性回顾性研究在位于西班牙马德里La Paz-Carlos III医院的国家输入性热带病转诊单位进行。这项研究包括了一个舞蹈和打击乐团的14名成员，他们于2023年3月3日至3月18日前往几内亚共和国。确诊或可能患有血吸虫病的患者被纳入分析。结果12例疑似急性血吸虫病。其中78.5%为女性。主要临床表现为发热（91.6%）、嗜酸性粒细胞增多（100%）、急性腹泻（91.6%）、腹痛（83.3%）。所有患者均报告在几内亚有淡水接触史。所有病例的血吸虫血清学均呈阳性，5例患者的粪便样本显示存在曼氏血吸虫卵。急性症状用皮质类固醇治疗，所有病例的临床改善。此后，所有患者均接受吡喹酮治疗，剂量为40 mg/kg/天，间隔四周分两次给药。结论热带地区淡水暴露是血吸虫病发病的主要危险因素。急性期的早期诊断和治疗对于预防并发症和长期后遗症至关重要。

{"title":"Outbreak of Schistosomiasis mansoni in a Spanish dance and percussion ensemble acquired in the Republic of Guinea","authors":"Marta Arsuaga Vicente , Guillermo Ruiz-Carrascoso , Fernando De la Calle-Prieto , Javier Sotillo Gallego , Rosa De Miguel-Buckley , Mar Lago Nuñez , Daniel Mesado Martinez , Marta Díaz Menéndez","doi":"10.1016/j.eimc.2025.01.012","DOIUrl":"10.1016/j.eimc.2025.01.012","url":null,"abstract":"<div><h3>Introduction</h3><div>Schistosomiasis is a neglected tropical disease endemic in 78 countries worldwide. The acute phase, commonly referred to as Katayama fever, is more frequently observed in travelers than in migrants. Despite significant progress in understanding its pathology, many aspects of this disease remain unclear, posing challenges to timely diagnosis and management.</div></div><div><h3>Methods</h3><div>This observational retrospective study was conducted at the National Referral Unit for Imported Tropical Diseases, located at Hospital La Paz-Carlos III in Madrid, Spain. The study included a total of 14 members of a dance and percussion ensemble that traveled to the Republic of Guinea from March 3 to March 18, 2023. Patients with confirmed or probable schistosomiasis were included in the analysis.</div></div><div><h3>Results</h3><div>Twelve patients had suspected acute schistosomiasis. Of these, 78.5% were female. The predominant clinical manifestations included fever (91.6%), eosinophilia (100%), acute diarrhea (91.6%), and abdominal pain (83.3%). All patients reported a history of freshwater exposure in Guinea. Schistosoma serology was positive in all cases, and stool samples from five patients revealed the presence of <em>Schistosoma mansoni</em><span> eggs. Acute symptoms were managed with corticosteroids, leading to clinical improvement in all cases. Thereafter, all patients were treated with praziquantel at a dose of 40</span> <!-->mg/kg/day, administered in two separate doses four weeks apart.</div></div><div><h3>Conclusion</h3><div>Freshwater exposure in tropical regions is the primary risk factor for acquiring schistosomiasis. Early diagnosis and treatment during the acute phase are crucial to prevent complications and long-term sequelae.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 9","pages":"Pages 571-576"},"PeriodicalIF":2.5,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145425740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cólicos renoureterales de un año de evolución con urocultivos negativos: desafío diagnóstico 尿道培养呈阴性的1年进化期非尿道结肠炎：诊断挑战

IF 2.5 4区医学 Q3 INFECTIOUS DISEASES

Enfermedades infecciosas y microbiologia clinica

Pub Date : 2025-11-01 DOI: 10.1016/j.eimc.2025.04.004

Ramón Vela-Fernández, Natalia Montiel Quezel-Guerraz, Teresa Trujillo Soto, Manuel Antonio Rodríguez-Iglesias

引用次数: 0

Infección de prótesis articular por Listeria monocytogenes: a propósito de 2 casos clínicos y revisión de la literatura 单核细胞增生李斯特菌关节假体感染：针对2例临床病例和文献综述

IF 2.5 4区医学 Q3 INFECTIOUS DISEASES

Enfermedades infecciosas y microbiologia clinica

Pub Date : 2025-11-01 DOI: 10.1016/j.eimc.2025.05.003

Begoña Fachal Bugarín, Lucía Ramos Merino, Joaquín Manuel Serrano Arreba, Alicia Alonso Álvarez, Ramón María Fernández Varela, Berta Pernas Souto, Laura Gutiérrez Fernández, María Dolores Sousa Regueiro, Enrique Míguez Rey, Efrén Sánchez Vidal

Introduction

Most infections caused by Listeria monocytogenes occur in individuals with predisposing conditions, such as advanced age or the use of immunosuppressive therapies, and primarily manifest as bacteremia or meningoencephalitis. Osteoarticular infections are uncommon and typically affect joint prostheses, with late-onset infections following surgery. Treatment in these cases should include antibiotic therapy along with a surgical strategy, which generally involves the removal of the affected prosthesis.

Methods

Two cases of prosthetic joint infection caused by L. monocytogenes are presented, along with a narrative review of the English and Spanish literature via PubMed® up to December 2024.

Results

To the best of our knowledge, 52 cases of prosthetic joint infection caused by L. monocytogenes have been reported since 2000. All patients had predisposing conditions, with advanced age being the most common (mean age of 71 years). Most cases were late infections following surgery. Combined treatment (antibiotic therapy and surgery) was used in two-thirds of cases. The prognosis was favorable in almost all instances.

Discussion

It is important to consider L. monocytogenes in the etiological diagnosis of prosthetic joint infections, especially in elderly or immunocompromised patients. While the most used antibiotics have been ampicillin and cotrimoxazole, oxazolidinones could serve as an oral alternative for the treatment of these infections.

大多数由单核细胞增生李斯特菌引起的感染发生在有易感条件的个体中，如高龄或使用免疫抑制疗法，主要表现为菌血症或脑膜脑炎。骨关节感染不常见，通常影响关节假体，手术后迟发性感染。这些病例的治疗应包括抗生素治疗和手术治疗，通常包括切除受影响的假体。方法报告2例由单核增生L.菌引起的假体关节感染病例，并通过PubMed®对截至2024年12月的英文和西班牙文文献进行叙述性回顾。结果自2000年以来，共报告52例假体关节感染病例。所有患者都有易感条件，以高龄最常见（平均年龄71岁）。大多数病例为手术后晚期感染。三分之二的病例采用联合治疗（抗生素治疗和手术）。几乎所有病例的预后都是良好的。在假体关节感染的病原学诊断中，特别是在老年人或免疫功能低下的患者中，考虑单核细胞增生乳杆菌是很重要的。虽然最常用的抗生素是氨苄西林和复方新诺明，但恶唑烷酮可以作为治疗这些感染的口服替代药物。

{"title":"Infección de prótesis articular por Listeria monocytogenes: a propósito de 2 casos clínicos y revisión de la literatura","authors":"Begoña Fachal Bugarín, Lucía Ramos Merino, Joaquín Manuel Serrano Arreba, Alicia Alonso Álvarez, Ramón María Fernández Varela, Berta Pernas Souto, Laura Gutiérrez Fernández, María Dolores Sousa Regueiro, Enrique Míguez Rey, Efrén Sánchez Vidal","doi":"10.1016/j.eimc.2025.05.003","DOIUrl":"10.1016/j.eimc.2025.05.003","url":null,"abstract":"<div><h3>Introduction</h3><div>Most infections caused by <em>Listeria monocytogenes</em> occur in individuals with predisposing conditions, such as advanced age or the use of immunosuppressive therapies, and primarily manifest as bacteremia or meningoencephalitis. Osteoarticular infections are uncommon and typically affect joint prostheses, with late-onset infections following surgery. Treatment in these cases should include antibiotic therapy along with a surgical strategy, which generally involves the removal of the affected prosthesis.</div></div><div><h3>Methods</h3><div>Two cases of prosthetic joint infection caused by <em>L. monocytogenes</em> are presented, along with a narrative review of the English and Spanish literature via PubMed® up to December 2024.</div></div><div><h3>Results</h3><div>To the best of our knowledge, 52 cases of prosthetic joint infection caused by <em>L. monocytogenes</em> have been reported since 2000. All patients had predisposing conditions, with advanced age being the most common (mean age of 71 years). Most cases were late infections following surgery. Combined treatment (antibiotic therapy and surgery) was used in two-thirds of cases. The prognosis was favorable in almost all instances.</div></div><div><h3>Discussion</h3><div>It is important to consider <em>L. monocytogenes</em> in the etiological diagnosis of prosthetic joint infections, especially in elderly or immunocompromised patients. While the most used antibiotics have been ampicillin and cotrimoxazole, oxazolidinones could serve as an oral alternative for the treatment of these infections.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 9","pages":"Pages 591-595"},"PeriodicalIF":2.5,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145425687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ante una picadura de garrapata en España, ¿qué riesgo de infección hay? 在西班牙，蜱虫叮咬有多大的感染风险？

IF 2.5 4区医学 Q3 INFECTIOUS DISEASES

Enfermedades infecciosas y microbiologia clinica

Pub Date : 2025-11-01 DOI: 10.1016/j.eimc.2025.06.012

María Cruz Calvo Reyes , Juan Antonio del Castillo Polo , Esther García-Expósito , Esteban Aznar Cano , Laura Santos Larrégola , María José Sierra Moros , Lucía García-San Miguel

Introduction

The development of parameters to estimate the risk of transmission of infections is one of the objectives of entomological surveillance, included in the National Plan for the Prevention, Surveillance and Control of Vector-Borne Diseases. This study aims to assess the utility of the infection prevalence (IP) of Rickettsia spp., Borrelia burgdorferi, and Crimean-Congo haemorrhagic fever virus in ticks in Spain, as an indicator of the risk of infection from a tick bite and for temporal and geographical comparisons.

Methods

The IP and its 95% confidence interval were calculated for the different microorganism-tick pairs, using data published until April 2024, obtained through a systematic literature review. Studies that included pathogen detection using molecular methods in ticks collected from vegetation (questing ticks) were selected.

Results

Five hundred and eighty-one articles were reviewed, and 20 were selected. The IP of Rickettsia spp. in Dermacentor marginatus was 84.4%, in D. reticulatus 45.9%, and in Rhipicephalus sanguineus 21.2%, with some Rickettsia species causing DEBONEL (R. raoultii and R. slovaca) and MSF-like illness (R. massiliae) being the most frequent. The IP of Borrelia burgdorferi sensu lato in Ixodes ricinus was 5.9%. The IP of Crimean-Congo haemorrhagic fever virus in Hyalomma spp. was 0.3%.

Conclusions

The IP varies for each pathogen-tick pair, from very high for Rickettsia in Dermacentor, to relatively low for Borrelia in Ixodes and Crimean-Congo haemorrhagic fever virus in Hyalomma. The IP in ticks can be a useful indicator, along with other factors, for estimating the risk of infection from a tick bite and conducting population risk assessments in Spain.

制定参数以估计感染传播的风险是昆虫学监测的目标之一，已列入《国家媒介传播疾病预防、监测和控制计划》。本研究旨在评估西班牙蜱虫中立克次体、伯氏疏螺旋体和克里米亚-刚果出血热病毒感染流行率（IP）的效用，作为蜱叮咬感染风险的指标，并进行时间和地理比较。方法利用截至2024年4月发表的文献资料，计算不同微生物-蜱虫对的IP值及其95%置信区间。选择了利用分子方法对植物采集的蜱进行病原检测的研究（探索蜱）。结果共审稿581篇，入选20篇。立克次体在边缘革螨中的感染率为84.4%，在网状革螨中的感染率为45.9%，在血鼻头虫中的感染率为21.2%，其中一些立克次体引起的疾病（拉乌尔氏革螨和斯洛瓦氏革螨）和无国界医生样疾病（马氏革螨）最为常见。蓖麻伊蚊中感应伯氏疏螺旋体的感染率为5.9%。克里米亚-刚果出血热病毒在透明眼蝇中的感染率为0.3%。结论不同病原体-蜱对的IP值不同，革螨的立克次体IP值较高，伊蚊的伯氏体IP值较低，透明瘤的克里米亚-刚果出血热病毒IP值较低。在西班牙，蜱虫中的IP可作为一个有用的指标，与其他因素一起，用于估计蜱虫叮咬感染的风险并进行人口风险评估。

{"title":"Ante una picadura de garrapata en España, ¿qué riesgo de infección hay?","authors":"María Cruz Calvo Reyes , Juan Antonio del Castillo Polo , Esther García-Expósito , Esteban Aznar Cano , Laura Santos Larrégola , María José Sierra Moros , Lucía García-San Miguel","doi":"10.1016/j.eimc.2025.06.012","DOIUrl":"10.1016/j.eimc.2025.06.012","url":null,"abstract":"<div><h3>Introduction</h3><div>The development of parameters to estimate the risk of transmission of infections is one of the objectives of entomological surveillance, included in the National Plan for the Prevention, Surveillance and Control of Vector-Borne Diseases. This study aims to assess the utility of the infection prevalence (IP) of <em>Rickettsia</em> spp., <em>Borrelia burgdorferi</em>, and Crimean-Congo haemorrhagic fever virus in ticks in Spain, as an indicator of the risk of infection from a tick bite and for temporal and geographical comparisons.</div></div><div><h3>Methods</h3><div>The IP and its 95% confidence interval were calculated for the different microorganism-tick pairs, using data published until April 2024, obtained through a systematic literature review. Studies that included pathogen detection using molecular methods in ticks collected from vegetation (questing ticks) were selected.</div></div><div><h3>Results</h3><div>Five hundred and eighty-one articles were reviewed, and 20 were selected. The IP of <em>Rickettsia</em> spp. in <em>Dermacentor marginatus</em> was 84.4%, in <em>D. reticulatus</em> 45.9%, and in <em>Rhipicephalus sanguineus</em> 21.2%, with some <em>Rickettsia</em> species causing DEBONEL (<em>R. raoultii</em> and <em>R. slovaca</em>) and MSF-like illness <em>(R. massiliae)</em> being the most frequent. The IP of <em>Borrelia burgdorferi</em> <em>sensu lato</em> in <em>Ixodes ricinus</em> was 5.9%. The IP of Crimean-Congo haemorrhagic fever virus in <em>Hyalomma</em> spp. was 0.3%.</div></div><div><h3>Conclusions</h3><div>The IP varies for each pathogen-tick pair, from very high for <em>Rickettsia</em> in <em>Dermacentor</em>, to relatively low for <em>Borrelia</em> in <em>Ixodes</em> and Crimean-Congo haemorrhagic fever virus in <em>Hyalomma</em>. The IP in ticks can be a useful indicator, along with other factors, for estimating the risk of infection from a tick bite and conducting population risk assessments in Spain.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 9","pages":"Pages 600-606"},"PeriodicalIF":2.5,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145425690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cribado de infecciones de transmisión sexual en población trans e interacción del tratamiento hormonal reafirmante de género con la terapia antirretroviral 对跨性别人群中的性传播感染进行筛查，以及性别强化激素治疗与抗逆转录病毒治疗之间的相互作用

IF 2.5 4区医学 Q3 INFECTIOUS DISEASES

Enfermedades infecciosas y microbiologia clinica

Pub Date : 2025-11-01 DOI: 10.1016/j.eimc.2025.04.006

Esteban Sánchez-Toscano , Dunia Collazo-Yáñez , Jesús Domínguez-Riscart , Laura Larrán-Escandón , Andrés Martín-Aspas , Isabel Mateo-Gavira , Manuel Aguilar-Diosdado

Introduction

Current evidence suggests that transgender people have a higher risk of sexually transmitted infections (STIs) than general population, although most of the literature focuses on transwomen with HIV.

Objective

To determine the prevalence of STDs diagnosed by serology in transgender population in our hospital and to analyze the impact of antiretroviral treatment on hormonal therapy.

Methods

We design a cross-sectional study based on medical records of transgender people treated at the Transgender Care Unit of Cadiz from June 2022 to June 2023. Hepatitis, HIV and syphilis serology was requested from people between 16 and 65 years.

Results

A total of 295 people were included, 48,14% transwomen (n = 142) and 51,86% transmen (n = 153), with an average age of 24,78 ± 9,2 years. It was detected 14 cases of HAV, 5 of syphilis, 3 of HBV and 3 of HCV. Prevalence of HIV was 3,73% (n = 11). Of the 9 transwomen with HIV infection, 3 of them required a change in antiretroviral medication and 2 cases required changes in the route of estrogen administration to achieve optimal plasma hormone levels.

Conclusions

With the current model of care for transgender people in Andalusia, the prevalence of STDs detected in our sociocultural environment is low. Special attention should be paid to possible interactions between antiretroviral treatment and hormone therapy, especially in transwomen.

目前的证据表明，变性人患性传播感染（STIs）的风险高于一般人群，尽管大多数文献关注的是感染艾滋病毒的变性女性。目的了解我院跨性别人群性传播疾病血清学诊断情况，分析抗逆转录病毒治疗对激素治疗的影响。方法基于2022年6月至2023年6月在加的斯变性人护理中心治疗的变性人的医疗记录，设计了一项横断面研究。肝炎、艾滋病毒和梅毒的血清学要求来自16至65岁之间的人。结果共纳入295人，其中跨性别者占48.14% (n = 142)，跨性别者占51.86% (n = 153)，平均年龄（24.78±9.2）岁。检出甲型肝炎14例，梅毒5例，乙型肝炎3例，丙型肝炎3例。HIV患病率为3.73% （n = 11）。9例感染HIV的跨性别女性中，3例需要改变抗逆转录病毒药物治疗，2例需要改变雌激素给药途径以达到最佳血浆激素水平。结论在安达卢西亚现有的跨性别人群护理模式下，性病检出率在我们的社会文化环境中较低。应特别注意抗逆转录病毒治疗和激素治疗之间可能的相互作用，特别是在跨性别妇女中。

{"title":"Cribado de infecciones de transmisión sexual en población trans e interacción del tratamiento hormonal reafirmante de género con la terapia antirretroviral","authors":"Esteban Sánchez-Toscano , Dunia Collazo-Yáñez , Jesús Domínguez-Riscart , Laura Larrán-Escandón , Andrés Martín-Aspas , Isabel Mateo-Gavira , Manuel Aguilar-Diosdado","doi":"10.1016/j.eimc.2025.04.006","DOIUrl":"10.1016/j.eimc.2025.04.006","url":null,"abstract":"<div><h3>Introduction</h3><div>Current evidence suggests that transgender people have a higher risk of sexually transmitted infections (STIs) than general population, although most of the literature focuses on transwomen with HIV.</div></div><div><h3>Objective</h3><div>To determine the prevalence of STDs diagnosed by serology in transgender population in our hospital and to analyze the impact of antiretroviral treatment on hormonal therapy.</div></div><div><h3>Methods</h3><div>We design a cross-sectional study based on medical records of transgender people treated at the Transgender Care Unit of Cadiz from June 2022 to June 2023. Hepatitis, HIV and syphilis serology was requested from people between 16 and 65 years.</div></div><div><h3>Results</h3><div>A total of 295 people were included, 48,14% transwomen (n=142) and 51,86% transmen (n=153), with an average age of 24,78±9,2 years. It was detected 14 cases of HAV, 5 of syphilis, 3 of HBV and 3 of HCV. Prevalence of HIV was 3,73% (n=11). Of the 9 transwomen with HIV infection, 3 of them required a change in antiretroviral medication and 2 cases required changes in the route of estrogen administration to achieve optimal plasma hormone levels.</div></div><div><h3>Conclusions</h3><div>With the current model of care for transgender people in Andalusia, the prevalence of STDs detected in our sociocultural environment is low. Special attention should be paid to possible interactions between antiretroviral treatment and hormone therapy, especially in transwomen.</div></div>","PeriodicalId":11608,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica","volume":"43 9","pages":"Pages 585-590"},"PeriodicalIF":2.5,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145425744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A propósito de un caso: mastitis puerperal complicada 关于一个案例：复杂的产后乳腺炎

IF 2.5 4区医学 Q3 INFECTIOUS DISEASES

Enfermedades infecciosas y microbiologia clinica

Pub Date : 2025-11-01 DOI: 10.1016/j.eimc.2025.02.009

Maialen Larrea Ayo, Begoña Vilar Achabal, Elena Urra Zalbidegoitia, Mikel Gallego Rodrigo

引用次数: 0

Celulitis meningocócica en contexto de infección por SARS-CoV-2: una presentación inusual SARS-CoV-2感染背景下的脑膜炎球菌性细胞炎：不寻常的发病

IF 2.5 4区医学 Q3 INFECTIOUS DISEASES

Enfermedades infecciosas y microbiologia clinica

Pub Date : 2025-11-01 DOI: 10.1016/j.eimc.2025.06.004

María Calle Romero, Patricia de la Montaña Díaz, Montserrat Rodríguez Gómez, Fernando Martínez Sagasti

引用次数: 0

首页上一页

下一页尾页

类型

全部化学•材料生命科学医学物理工程技术环境•农林材料科学地球科学法学管理学化学环境科学与生态学计算机科学教育学经济学农林科学人文科学生物学数学物理与天体物理心理学综合性期刊其他工业工程理学历史学农学文学信息工程

数据库

全部 ACS Publications Elsevier ieeexplore Springer The Royal Society of Chemistry Wiley

期刊

Enfermedades infecciosas y microbiologia clinica

全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.

﹀