Enfermedades infecciosas y microbiologia clinica最新文献

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IF 2.5 4区医学 Q3 INFECTIOUS DISEASES

Enfermedades infecciosas y microbiologia clinica

Pub Date : 2026-01-01

引用次数: 0

IF 2.5 4区医学 Q3 INFECTIOUS DISEASES

Enfermedades infecciosas y microbiologia clinica

Pub Date : 2026-01-01

引用次数: 0

IF 2.5 4区医学 Q3 INFECTIOUS DISEASES

Enfermedades infecciosas y microbiologia clinica

Pub Date : 2026-01-01

引用次数: 0

IF 2.5 4区医学 Q3 INFECTIOUS DISEASES

Enfermedades infecciosas y microbiologia clinica

Pub Date : 2026-01-01

引用次数: 0

Acute Q fever in Spain: Aligning diagnosis and one health surveillance 西班牙急性Q热：统一诊断和健康监测

IF 2.5 4区医学 Q3 INFECTIOUS DISEASES

Enfermedades infecciosas y microbiologia clinica

Pub Date : 2025-12-01 DOI: 10.1016/j.eimc.2025.08.001

Francisco Carmona-Torre, Maialen Ibarguren Pinilla, Miguel Ángel Goenaga

引用次数: 0

The current challenge of accurately diagnosing new HIV infections 当前的挑战是准确诊断新的艾滋病毒感染

IF 2.5 4区医学 Q3 INFECTIOUS DISEASES

Enfermedades infecciosas y microbiologia clinica

Pub Date : 2025-12-01 DOI: 10.1016/j.eimc.2025.07.005

Sergio Fuente-García , Laura Martínez-García , Ana Moreno , Juan Carlos Galán

引用次数: 0

Fibrosis mediastínica como complicación de la infección por Histoplasma capsulatum en paciente inmunocomprometida 作为免疫受损患者囊性组织质感染并发症的介质纤维化

IF 2.5 4区医学 Q3 INFECTIOUS DISEASES

Enfermedades infecciosas y microbiologia clinica

Pub Date : 2025-12-01 DOI: 10.1016/j.eimc.2025.05.007

Susana Laura García Aguilera , Beatriz Villar Navas , Alba Mohedano Sánchez , Nerea Mohino Farré

引用次数: 0

Fiebre Q aguda en Mallorca, 2017-2022. Un problema infraestimado 2017-2022年马略卡岛急性Q热。被低估的问题

IF 2.5 4区医学 Q3 INFECTIOUS DISEASES

Enfermedades infecciosas y microbiologia clinica

Pub Date : 2025-12-01 DOI: 10.1016/j.eimc.2025.01.004

Mercedes García-Gasalla , Sophia Pinecki Socias , Pablo A. Fraile , Victoria Fernández-Baca , Aroa Villoslada , Antonio Adrover , Sandra Gregorio , Marta González-Moreno , Alfredo Pinheiro Martins , Alexander Zidouh , Gemma Mut , Meritxell Gavaldà , Melchor Riera , Luisa Martín Pena , Javier Murillas Angoiti

Introduction

Q fever (QF) is a zoonotic infection caused by Coxiella burnetii. Previous studies suggest that the incidence in the island of Majorca may be high. The objective was to know the epidemiological, clinical, diagnostic, and therapeutic characteristics of acute QF (AQF) on the island of Majorca during the years 2017 to 2022.

Methods

Retrospective analysis of a series of cases of AQF diagnosed in 3 out 4 hospitals of the Health Service of the island of Majorca. AQF was considered if a clinically compatible syndrome was present with one of the following serological criteria: confirmed AQF if IgG seroconversion phase II, very possible if only IgG ≥ 1/128 is available in addition to a positive IgM, and AQF possible if IgG ≥ 1/512 with negative IgM or if IgM positive with negative IgG in a single serological determination.

Results

223 cases of AQF were diagnosed, of which 102 (45.7%) were confirmed, 84 (37.7%) very possible and 37 (16.6%) possible AQF. Prolonged febrile syndrome was the most frequent clinical diagnosis (107, 48.0%), followed by pneumonia with/without pleural effusion (49, 21.9%), acute hepatitis (38, 17.0%), pericarditis and/or myocarditis (6, 2.6%). Three patients developed endocarditis (one in the acute phase, two others during follow-up). The median number of cases per year was 34 (p25-p75: 31.7 - 40.25). AQF-related mortality was 1.8% (4 patients).

Conclusion

AQF is a preventable and little recognized zoonosis, causing significant morbidity and mortality in Majorca.

q热是一种由伯纳克希菌引起的人畜共患感染。先前的研究表明，马略卡岛的发病率可能很高。目的是了解2017年至2022年马略卡岛急性QF （AQF）的流行病学、临床、诊断和治疗特征。方法回顾性分析马略卡岛卫生服务部门4所医院中3所诊断的一系列AQF病例。如果临床相容综合征存在以下血清学标准之一，则考虑AQF：如果IgG血清转化期为确诊AQF，如果IgG≥1/128且IgM阳性，则极有可能，如果IgG≥1/512且IgM阴性或IgM阳性且IgG阴性，则AQF可能。结果确诊AQF 223例，确诊102例（45.7%），非常可能84例（37.7%），可能37例（16.6%）。延长热综合征是最常见的临床诊断（107例，48.0%），其次是肺炎合并/不合并胸腔积液（49例，21.9%），急性肝炎（38例，17.0%），心包炎和/或心肌炎（6例，2.6%）。3例患者发生心内膜炎（1例急性期，2例随访）。每年中位病例数为34例（p25-p75: 31.7 - 40.25）。aqf相关死亡率为1.8%（4例）。结论马略卡岛aqf是一种可预防的人畜共患疾病，发病率和死亡率均较高。

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引用次数: 0

Unsuccessful tuberculosis-treatment in HIV-positive patients and associated factors hiv阳性患者结核病治疗失败及其相关因素

IF 2.5 4区医学 Q3 INFECTIOUS DISEASES

Enfermedades infecciosas y microbiologia clinica

Pub Date : 2025-12-01 DOI: 10.1016/j.eimc.2025.06.008

Guillermo Bosch , Joan-Pau Millet , Àngels Orcau , Isabel Moreira , Carles Pericas , Lluïsa Forns , Isabel Marcos , Raquel Prieto , Anna Hernandez , Lídia Arranz , Cristina Rius

Background

TB is one of the most deathly infections worldwide, affecting disproportionally people living with HIV (PLHIV). Furthermore, HIV co-infection is related to worse outcomes for TB patients, including lower treatment success.

Methods

Using surveillance records of all TB cases notified in Barcelona city from 2001 to 2021, we analyzed TB treatment success according to HIV status. Additionally, we explored potential social and health related and factors associated to unsuccessful treatment in PLHIV, using multiple regression analyses.

Results

Out of the 8406 new TB cases diagnosed during the study period, 9% were co-infected with HIV. According to our regression models, PLHIV were more frequently men, users of injected drugs (aOR = 45.81; 95% CI (33.10–64.26)), had previously been treated for TB (aOR = 1.77; 95% CI (1.30–2.40)) and had a lower rate of contact tracing (aOR = 0.51; 95% CI (0.40–0.64)). Among PLHIV, unsuccessful treatment was related to the use of injected drugs and homelessness, but it was lower for those who had undergone contact tracing.

Conclusion

PLHIV have higher odds of unsuccessful TB treatment, especially those who are homeless and use injected drugs. Contact tracing improved treatment success, calling for further efforts and resources to correctly follow-up on these patients, with the goal of increasing treatment success.

结核病是全世界最致命的传染病之一，对艾滋病毒感染者（PLHIV）的影响不成比例。此外，艾滋病毒合并感染与结核病患者预后较差有关，包括治疗成功率较低。方法利用巴塞罗那市2001 - 2021年报告的所有结核病例监测记录，根据HIV感染情况分析结核治疗成功情况。此外，我们利用多元回归分析探讨了与hiv治疗失败相关的潜在社会和健康因素。结果在研究期间诊断的8406例新结核病例中，9%合并感染艾滋病毒。根据我们的回归模型，PLHIV感染者多为男性，注射药物使用者（aOR = 45.81; 95% CI(33.10-64.26)），以前接受过结核病治疗（aOR = 1.77; 95% CI(1.30-2.40)），接触者追踪率较低（aOR = 0.51; 95% CI(0.40-0.64)）。在艾滋病毒感染者中，治疗失败与注射毒品的使用和无家可归有关，但与那些接受过接触者追踪的人有关。结论艾滋病毒感染者结核病治疗失败的几率较高，尤其是无家可归者和注射吸毒者。接触者追踪提高了治疗成功率，要求进一步努力和投入资源，对这些患者进行正确的随访，目标是提高治疗成功率。

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Sobre «Análisis comparativo de las infecciones respiratorias agudas de etiología viral en menores de 6 meses con y sin nirsevimab en Baleares (2022-2023 y 2023-2024)» 关于“巴利阿里群岛（2022-2023年和2023-2024年）使用和不使用nirsevimab的6个月以下儿童急性病毒性呼吸道感染的比较分析”

IF 2.5 4区医学 Q3 INFECTIOUS DISEASES

Enfermedades infecciosas y microbiologia clinica

Pub Date : 2025-12-01 DOI: 10.1016/j.eimc.2025.06.020

Paula Corihuela Menéndez, Sacramento M. Segovia López, Alejandra Méndez Sánchez, Lara González García

引用次数: 0

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