Enfermedades infecciosas y microbiologia clinica最新文献

英文中文

Prevalencia y características clínico-epidemiológicas de la hepatitis crónica por el virus de la hepatitis delta en la isla de Gran Canaria 大加那利岛慢性乙型肝炎病毒性肝炎的发病率和临床流行病学特征。

IF 2.6 4区医学 Q3 INFECTIOUS DISEASES

Enfermedades infecciosas y microbiologia clinica

Pub Date : 2024-11-01 DOI: 10.1016/j.eimc.2024.06.008

Goretti Redondo Betancor , Melisa Hernández Febles , Raquel Zaragozá González , Rafael Granados Monzón , Ildefonso Quiñones Morales , Adolfo de Salazar , Federico García García , María José Pena López

Objective

The objective of this study was to know the prevalence and clinical-epidemiological characteristics of patients with chronic infection due to hepatitis D virus (HDV).

Patients and methods

A retrospective descriptive study was carried out on patients with HDV infection under follow-up in a hospital in 2023. All patients carrying HBsAg were tested for antibodies against HDV. HDV RNA detection was performed in all antibody-positive samples. The medical records were reviewed.

Results

Of the 340 patients carrying HBsAg, 24 (7.1%) had anti-HDV antibodies, and 6 (25%) had detectable HDV RNA (chronic infection). The prevalence of chronic hepatitis in HBsAg carriers was 1.8%. All patients had a genotype 1 infection. Half of the patients were of African origin and 29.2% were Spanish. Of the 6 patients with chronic infection, 5 (83.3%) had cirrhosis and 2 (33.3%) had hepatocellular carcinoma. Half of the patients had some exacerbation of the disease during follow-up. Of the 18 patients without viremia, 2 (11.1%) presented cirrhosis (one recently diagnosed). The mean follow-up time of patients without viremia was 13.5 years.

Conclusions

The prevalence of chronic HDV hepatitis in our area is low and in all cases it presents as an advanced disease, with exacerbations during follow-up. Patients without viremia have probably resolved the infection, as viremia was not detected in any moment.

本研究旨在了解丁型肝炎病毒（HDV）慢性感染患者的患病率和临床流行病学特征。患者和方法对 2023 年在一家医院接受随访的 HDV 感染患者进行了回顾性描述性研究。对所有携带 HBsAg 的患者进行了 HDV 抗体检测。对所有抗体阳性样本进行了 HDV RNA 检测。结果在 340 名携带 HBsAg 的患者中，24 人（7.1%）有抗 HDV 抗体，6 人（25%）检测到 HDV RNA（慢性感染）。HBsAg 携带者中慢性肝炎的发病率为 1.8%。所有患者均为基因型 1 感染。半数患者为非洲裔，29.2%为西班牙裔。在 6 名慢性感染患者中，5 人（83.3%）患有肝硬化，2 人（33.3%）患有肝细胞癌。半数患者在随访期间病情有所加重。在 18 名无病毒感染的患者中，有 2 人（11.1%）患有肝硬化（其中一人最近确诊）。无病毒血症患者的平均随访时间为 13.5 年。结论慢性 HDV 肝炎在我们地区的发病率较低，所有病例均为晚期，随访期间病情加重。没有病毒血症的患者很可能已经摆脱了感染，因为在任何时候都没有检测到病毒血症。

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引用次数: 0

Resultados de la encuesta nacional de REIV-TOXO sobre el cribado gestacional de la toxoplasmosis en España 西班牙 REIV-TOXO 全国妊娠弓形虫病筛查调查结果

IF 2.6 4区医学 Q3 INFECTIOUS DISEASES

Enfermedades infecciosas y microbiologia clinica

Pub Date : 2024-11-01 DOI: 10.1016/j.eimc.2023.08.004

Introduction

Currently, the status of serological screening for toxoplasmosis in pregnant women in Spain is unknown, and there is no official recommendation. The objective of this study is to show the current practice of gestational screening for toxoplasmosis in hospitals belonging to the Spanish Network for Research on Congenital Toxoplasmosis (REIV-TOXO).

Methods

An electronic survey was sent between April 2021 and September 2021 to investigators from 118 hospitals of REIV-TOXO, representing all Spanish regions. Nine items related to gestational screening for toxoplasmosis were collected. This information was compared with cases of congenital toxoplasmosis (CT) identified in REIV-TOXO to determine if these were diagnosed in the presence of gestational screening.

Results

During the study period, serological screening was performed in 53.3% (63/118) hospitals, with variations between regions and even among hospitals within the same region. Testing performed in each trimester was the most common practice (57.7%), followed by a single determination (24.4%). 89.4% of CT cases between January 2015 and September 2021 were diagnosed due to gestational screening.

Conclusion

The decision to perform gestational screening for toxoplasmosis in Spain is highly heterogeneous, with significant local and regional differences. Despite this, screening still allows the diagnosis of most CT cases. It is urgent to have current epidemiological data to inform decision-making in public health.

导言：目前，西班牙孕妇弓形虫血清学筛查的情况尚不清楚，也没有官方建议。本研究旨在介绍西班牙先天性弓形虫病研究网络（REIV-TOXO）下属医院目前开展的妊娠期弓形虫病筛查工作。方法：在 2021 年 4 月至 2021 年 9 月期间，我们向代表西班牙所有地区的 118 家 REIV-TOXO 医院的调查人员发送了一份电子调查问卷。调查收集了与妊娠弓形虫筛查相关的九个项目。这些信息与 REIV-TOXO 发现的先天性弓形虫病（CT）病例进行了比较，以确定这些病例是否在妊娠筛查中被确诊。结果在研究期间，53.3%（63/118）的医院进行了血清学筛查，不同地区之间甚至同一地区不同医院之间都存在差异。在每个孕期进行检测是最常见的做法（57.7%），其次是一次性检测（24.4%）。2015年1月至2021年9月期间，89.4%的CT病例是通过妊娠筛查确诊的。尽管如此，筛查仍能诊断出大多数 CT 病例。当务之急是掌握最新的流行病学数据，为公共卫生决策提供依据。

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Índice de autores

IF 2.6 4区医学 Q3 INFECTIOUS DISEASES

Enfermedades infecciosas y microbiologia clinica

Pub Date : 2024-11-01 DOI: 10.1016/S0213-005X(24)00397-5

引用次数: 0

Comité de Honor, Comité Organizador, Comité Científico y Responsables de TRACK

IF 2.6 4区医学 Q3 INFECTIOUS DISEASES

Enfermedades infecciosas y microbiologia clinica

Pub Date : 2024-11-01 DOI: 10.1016/S0213-005X(24)00392-6

引用次数: 0

Acute and recent hepatitis C virus (HCV) infections in men having sex with men (MSM): Is the test&treat strategy fundamental to reduce the incidence in this population? 男男性行为者 (MSM) 中的急性和近期丙型肝炎病毒 (HCV) 感染：检测和治疗策略是降低这一人群发病率的根本吗？

IF 2.6 4区医学 Q3 INFECTIOUS DISEASES

Enfermedades infecciosas y microbiologia clinica

Pub Date : 2024-10-01 DOI: 10.1016/j.eimc.2024.08.003

Cristina Gómez Ayerbe

引用次数: 0

Patología infecciosa importada desde el hemisferio norte 从北半球传入的传染病学

IF 2.6 4区医学 Q3 INFECTIOUS DISEASES

Enfermedades infecciosas y microbiologia clinica

Pub Date : 2024-10-01 DOI: 10.1016/j.eimc.2023.12.009

引用次数: 0

Uso de isavuconazol en la meningitis criptocócica de un paciente cirrótico 在一名肝硬化患者的隐球菌脑膜炎中使用异黄酮唑

IF 2.6 4区医学 Q3 INFECTIOUS DISEASES

Enfermedades infecciosas y microbiologia clinica

Pub Date : 2024-10-01 DOI: 10.1016/j.eimc.2024.04.008

Jesús Fernández Plaza , Sandra Gregorio Malagón , Manuel Poyato Borrego , Rafael Luque Márquez

引用次数: 0

Lo agresivo no siempre es tumoral: osteomielitis por Bartonella henselae 侵袭性并不总是肿瘤性的：鸡形巴顿氏菌骨髓炎

IF 2.6 4区医学 Q3 INFECTIOUS DISEASES

Enfermedades infecciosas y microbiologia clinica

Pub Date : 2024-10-01 DOI: 10.1016/j.eimc.2024.03.010

引用次数: 0

Usefulness of decentralized sequencing networks on antimicrobial resistance surveillance 分散测序网络对抗菌药耐药性监测的作用

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Enfermedades infecciosas y microbiologia clinica

Pub Date : 2024-10-01 DOI: 10.1016/j.eimc.2024.04.011

引用次数: 0

Proponiendo el cambio de denominación de la viruela del mono (Mpox) en español a viruela M 建议将猴痘（Mpox）的西班牙语名称改为 Mpox。

IF 2.6 4区医学 Q3 INFECTIOUS DISEASES

Enfermedades infecciosas y microbiologia clinica

Pub Date : 2024-10-01 DOI: 10.1016/j.eimc.2024.08.002

Francisco Javier Membrillo de Novales , Jaime García Iglesias , Miriam J. Álvarez-Martínez , Luis E. Cuellar , María Eugenia Gutiérrez-Pimentel , Alexis M. Holguin , Virgilio Lezcano , Susana Lloveras , Mariella Raijmakers , Iván Arturo Rodríguez Sabogal , Adriana Sucari , Alfonso J. Rodriguez-Morales , en nombre de la Alianza Latinoamericana de Enfermedades Infecciosas y Microbiología Clínica (ALEIMC)

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