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Evaluation Anxiety Levels of Adult Patients and Parents of Adolescent Patients With Anaphylaxis 成人过敏反应患者及青少年过敏反应患者父母的焦虑水平评估
Pub Date : 2022-12-27 DOI: 10.35440/hutfd.1122524
E. Emre, A. Kan
Background: Anaphylaxis is a sudden onset condition that may progress with severe systemic symptoms and may be accompanied by life-threatening respiratory failure and cardiovascular shock. Exposure to a traumatic event may cause patients and their parents to fear reliving the same event, so they try to avoid risk factors. It was aimed to determine the anxiety and stress levels in adult patients and in parents of adolescent patients diagnosed with anaphylaxis and to compare them with healthy controls. Materials and Methods: A questionnaire-type study was conducted. Control group (group 1), adult pa-tients diagnosed with anaphylaxis (group 2), and parents (a mother or father) of adolescent diagnosed with anaphylaxis (group 3) were included in the study. The anxiety levels of participants were evaluated by State-Trait Anxiety Inventory (STAI).Results: A total of 163 participants were included in the study. Seventy-one participants were in the con-trol group, forty-four were in group 2, thirty-eight were in group 3. STAI-T and STAI-S scores of groups 2 and 3 were significantly higher than controls. No difference was found between groups 2 and 3 for STAI-T scores (p=0.8) and STAI-S scores (p=0.74). Conclusions: Adult patients diagnosed with anaphylaxis and parents of adolescents are more anxious than the normal healthy population. Anxiety and anaphylactic conditions are often comorbid. Psychosocial assessment should be the first step in adult patients with anaphylaxis and their parents. Physicians should prevent the harm that anxiety may cause. For this purpose, education programs, screening programs, support trainings with patient participation should be organized.
背景:过敏性反应是一种突发性疾病,可发展为严重的全身症状,并可伴有危及生命的呼吸衰竭和心血管休克。接触创伤性事件可能会导致患者及其父母害怕再次经历同样的事件,因此他们试图避免风险因素。目的是确定成年患者和诊断为过敏反应的青少年患者的父母的焦虑和压力水平,并将其与健康对照进行比较。材料与方法:采用问卷式研究。对照组(1组)、诊断为过敏反应的成人患者(2组)和诊断为过敏反应的青少年的父母(母亲或父亲)(3组)被纳入研究。采用状态-特质焦虑量表(STAI)评估被试的焦虑水平。结果:本研究共纳入163名受试者。71名参与者在对照组,44名在第二组,38名在第三组。2、3组患者的sta - t、sta - s评分均显著高于对照组。第2组和第3组之间的STAI-T评分(p=0.8)和STAI-S评分(p=0.74)无差异。结论:诊断为过敏反应的成年患者和青少年家长的焦虑程度高于正常健康人群。焦虑和过敏性疾病通常是合并症。心理社会评估应是过敏反应成年患者及其父母的第一步。医生应该预防焦虑可能造成的伤害。为此,应组织有患者参与的教育项目、筛查项目和支持培训。
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引用次数: 0
Changes in the Prevalence of Neovascular Glaucoma in Individuals Over Sixty-Five Years of Age During the Covid-19 Pandemic Covid-19大流行期间65岁以上人群新生血管性青光眼患病率的变化
Pub Date : 2022-12-27 DOI: 10.35440/hutfd.1209137
M. Toptan
Amaç: Pandeminin farklı dönemlerinde 3. basamak bir hastaneye başvuran 65 yaş üstü neovasküler glokomlu olguların sayısında, GİB’ ı ve görme düzeylerindeki değişikliği incelemeyi amaçlamaktadır.Materyal ve metod: Hastalar karantina öncesi (21 mart 2019 -10 haziran 2019), karantina dönemi (21 mart 2020 -10 haziran 2020), karantina sonrası (21 mart 2021 -10 haziran 2021) 65 yaş üstü neovasküler glokom tanılı hastalar olmak üzere 3 gruba ayrıldı. Yaş, cinsiyet, dahil olan göz(ler), etiyoloji, göz içi basıncı (GİB), en iyi düzeltilmiş görme keskinliği (EİDGK), uygulanan tedaviler karşılaştırıldı.Bulgular: Karantina öncesi gruba göre karantina grubunda % 51.02, karantina sonrası grubunda % 14.29 oranında hasta sayısında azalma tespit ettik. Karantina döneminde uygulanan tedavi sayısı, karantina öncesi döneme göre % 51.85 azaldı (p=0.002). Karantina ve karantina sonrası dönem, karantina öncesi ile karşılaştırıldığında ortalama EİDGK seviyelerinde istatiksel anlamlı fark saptanmadı (p=0.078). Ancak ortalama GİB değerlerinde anlamlı fark tespit edildi (p<0.001) Sonuç: 65 yaş üstü neovasküler glokomlu hastaların karantina sürecinde ve sonrasında hastaneye başvurularında azalma tespit edildi. Karantina sürecinden sonra tedavinin gecikmesine bağlı olarak görme düzeylerinde azalma, GİB seviyelerinde yükselme mevcut idi. İlerleyen dönemlerde kaçınılmaz olarak neovasküler glokomlu hasta ve cerrahi sayısında artış görülecektir.
目的材料与方法:将患者分为 3 组:检疫前(2019 年 3 月 21 日至 2019 年 6 月 10 日)、检疫期(2020 年 3 月 21 日至 2020 年 6 月 10 日)、检疫后(2021 年 3 月 21 日至 2021 年 6 月 10 日)65 岁以上新生血管性青光眼患者。比较了年龄、性别、受累眼、病因、眼压(IOP)、最佳矫正视力(BCVA)和治疗方法:与检疫前相比,检疫组患者人数减少了 51.02%,检疫后减少了 14.29%;检疫期间的治疗次数比检疫前减少了 51.85%(P=0.002)。检疫期和检疫期后与检疫前相比,BCVA 平均水平无显著统计学差异(p=0.078)。不过,平均眼压值有明显差异(p<0.001):65 岁以上新生血管性青光眼患者在检疫期间和检疫之后的入院次数较少。隔离期结束后,由于治疗延误,视力下降,眼压水平升高。今后,新生血管性青光眼患者的人数和手术次数将不可避免地增加。
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引用次数: 0
The Effect of Mobile Phone on Hand Pain and Muscle Strength 手机对手部疼痛和肌肉力量的影响
Pub Date : 2022-12-27 DOI: 10.35440/hutfd.1187345
Ayşe Gül Kabakci, Sema ÖZANDAÇ POLAT, Emir İbrahim Işık, Gamze TAŞKIN ŞENOL
Background: Aim of the study determine the duration of mobile phone use on handgrip strength and thumb flexion muscle strength.Materials and method: The measurements were taken from hand dynamometer for handgrip strength and manual muscle tester for thumb flexion muscle strength. The means of the right and left handgrip strength, thumb flexion muscle strength were measured. Results: There was a statistically significant difference in height and weight measurements between genders (p<0.05). We found as using of mobile phone increased, hand strength increased. However, the highest value of thumb muscle strength on the right and left sides was observed to be over 8 hours. There was a high relation between gender and muscle strength measurements (p<0.05; r=0.700). Conclusion: This study revealed that the duration of mobile phone use has an effect on grip and thumb flexion muscle strength.
背景:本研究的目的是确定手机使用时间对握力和拇指屈曲肌力量的影响。材料和方法:测量方法为手握力测定仪和拇指屈曲肌力测定仪。测量右手、左手握力、拇指屈曲肌力量。结果:性别间身高、体重测量差异有统计学意义(p<0.05)。我们发现,随着手机使用的增加,手的力量也会增加。然而,左右两侧拇指肌肉力量的最大值被观察到超过8小时。性别与肌力测量值高度相关(p<0.05;r = 0.700)。结论:本研究揭示了手机使用时间长短对握力和拇指屈曲肌力量的影响。
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引用次数: 0
Could Some Measurements of the Scapula be Related to Rotator Cuff Syndrome? 肩胛骨的某些测量是否与肩袖综合征有关?
Pub Date : 2022-12-27 DOI: 10.35440/hutfd.1187836
B. Candan, E. Torun
Background: The scapula plays a unique role in shoulder movement and stability. The dimensions of the scapula and its geometry, however, are of essential importance in the pathomechanics of rotator cuff syndrome, total shoulder arthroplasty, and recurrent shoulder dislocation. The aim of this study is to determine the scapula morphology and to investigate with the relationship between rotator cuff syndrome.Materials and Methods: This study was a retrospective, observational study, and a total of 232 radiographs, 125 of which were male and 107 were female, were analyzed. The patients were divided into two groups as follows: Patients with rotator cuff syndrome (116 patients) and patients with no history of shoulder problems (116 patients). 9 different parameters were measured: The maximum scapular length, the maximum scapular width, the scapular index, the maximum glenoid cavity length, the maximum glenoid cavity width, the glenoid cavity index, the length of acromion, the distances between the acromion and coracoid process and length of the spina scapula.Results: The maximum scapular length, the maximum glenoid cavity length (p=0.009) and the length of spina scapula (p=0.041) were significantly different between the rotator cuff and control groups in evaluating parameters. All parameters were significantly different between male and female patients (p<0.05).Conclusion: A detailed knowledge of scapular anatomy is essential for successful total shoulder arthroplasty or surgical treatment of disorders related to scapula and shoulder. We think that the measurements of acromion, glenoid and scapula sizes obtained from our study will help surgeons to better understand shoulder morphology and to decide on the appropriate glenoid component size for shoulder arthroplasty. The fact that the lengths of the scapula, glenoid cavity and spina scapula are significantly different in rotator cuff syndrome suggests that scapula morphology may be effective in rotator cuff syndrome.
背景:肩胛骨在肩部运动和稳定中起着独特的作用。然而,肩胛骨的尺寸及其几何形状在肩袖综合征、全肩关节置换术和复发性肩关节脱位的病理力学中是至关重要的。本研究的目的是确定肩胛骨形态并探讨与肩袖综合征的关系。材料与方法:本研究为回顾性观察性研究,共分析232张x线片,其中男性125张,女性107张。患者分为两组:肩袖综合征患者(116例)和无肩关节病史患者(116例)。测量了9个不同的参数:最大肩胛骨长度、最大肩胛骨宽度、肩胛骨指数、最大肩胛腔长度、最大肩胛腔宽度、肩胛腔指数、肩峰长度、肩峰与喙突之间的距离和肩胛骨长度。结果:肩胛骨最大长度、肩胛骨最大盂腔长度(p=0.009)和肩胛骨棘长度(p=0.041)在评价参数上与对照组有显著性差异。男女患者各项指标差异均有统计学意义(p<0.05)。结论:详细的肩胛骨解剖学知识对于成功的全肩关节置换术或肩胛骨和肩部相关疾病的手术治疗至关重要。我们认为,从我们的研究中获得的肩峰、肩胛和肩胛骨大小的测量将有助于外科医生更好地了解肩关节的形态,并决定肩关节置换术中合适的肩胛组成部分的大小。肩胛骨、肩胛盂和脊柱肩胛骨的长度在肩袖综合征中存在显著差异,这表明肩胛骨形态在肩袖综合征中可能是有效的。
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引用次数: 0
Evaluation the Effect of 50 g Glucose Tolerance Test on Oxidative Stress and Interleukin-8 Parameters in Prediabetic Pregnancy 50 g糖耐量试验对妊娠糖尿病前期氧化应激及白细胞介素-8参数的影响
Pub Date : 2022-12-27 DOI: 10.35440/hutfd.1082328
Z. Özmen, C. Mertoğlu, L. Aydoğan, M. Nacar, K. Deveci, M. Katar, Zeki Özsoy
Background: The aim of this study is to evaluate the effect of 50 g oral glucose tolerance test (OGTT) on oxidative stress and interleukin-8 (IL-8) parameters in prediabetic pregnant women. Materials and Methods: Fasting and 1 hour blood samples were collected from 79 pregnant women who were administered 50 gr OGTT. Patients with a 1 hour blood glucose level of 140–200 mg/dl were considered as the prediabetic group. Thereafter, routine biochemical parameters and the levels of superoxide dismutase (SOD), glutathione peroxidase (GPx), malondialdehyde (MDA) and interleukin-8 (IL-8) parameters were measured from the serum samples taken during fasting and at 1 hour. Results: The serum GPx and SOD levels of the prediabetic group were remarkably lower than that of the control group (p<0.05). Whereas the serum IL-8 levels of the prediabetic group were significantly higher than that of the control group (p<0.05). When the fasting and 1 hour levels of the parameters were compared during OGTT, SOD levels were significantly decreased (p<0.001) and IL-8 levels were significantly higher (p<0.001). Conclusions: In conclusion, it was found that serum GPX and SOD levels decreased, while serum IL-8 levels increased in prediabetic pregnant women; however, when 50 g OGTT was administered to these patients, SOD levels decreased and IL-8 levels increased. These results we obtained suggest that oxidative stress and systemic inflammation that are already present in prediabetic pregnant women may be triggered by 50 g OGTT, posing negative risk factors for pregnant women.
背景:本研究旨在探讨50g口服糖耐量试验(OGTT)对糖尿病前期孕妇氧化应激和白细胞介素-8 (IL-8)参数的影响。材料与方法:采集79例接受50克OGTT治疗的孕妇的空腹和1小时血样。1小时血糖水平在140-200 mg/dl的患者被认为是糖尿病前期组。随后,测定空腹及1 h时血清常规生化指标及超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GPx)、丙二醛(MDA)、白细胞介素-8 (IL-8)水平。结果:糖尿病前期组血清GPx、SOD水平显著低于对照组(p<0.05)。而糖尿病前期组血清IL-8水平显著高于对照组(p<0.05)。对比OGTT期间空腹和1小时参数水平,SOD水平显著降低(p<0.001), IL-8水平显著升高(p<0.001)。结论:糖尿病前期孕妇血清GPX、SOD水平降低,血清IL-8水平升高;然而,当给予这些患者50 g OGTT时,SOD水平降低,IL-8水平升高。我们获得的这些结果表明,50 g OGTT可能会触发糖尿病前期孕妇已经存在的氧化应激和全身炎症,对孕妇构成负面危险因素。
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引用次数: 0
Üçüncü Basamak Bir Hastanede Yatan Tip 2 Diyabetli Hastalarda Hipertansiyon Sıklığı ve Etkileyen Faktörler
Pub Date : 2022-12-27 DOI: 10.35440/hutfd.1092287
M. Eren, Hüseyin Karaaslan, Mehmet Selim Mamiş, Ahmet Cebeli Gökay, Meliha Özkutlu, Tevfik Sabuncu
Amaç: Diyabet ve hipertansiyon birbirlerinin bulunma riskini arttıran, ayrıca kardiyak, vasküler ve renal kompli-kasyonlara neden olabilen yaygın hastalıklardır. Ayaktan takip edilen diyabetli hastalarda hipertansiyon sıklığı çoğu kez çalışılmışsa da yatan hastalar ile ilgili bilgiler kısıtlıdır. Biz de hastaneye yatan diyabetli hastalarda hipertansiyon sıklığını araştırmayı amaçladık.Materyal ve metod: Herhangi bir nedenle servise yatırılan tip 2 diyabetes mellituslu hastalar çalışmaya alındı. Hipertansiyon, antihipertansif ilaçlar almak veya hastanede ölçülen arteryel kan basıncının en az iki kez 140/90 mmHg’den daha yüksek çıkması olarak tanımlandı.Bulgular: Hastanede yatan tip 2 diyabet hastalarında hipertansiyon sıklığı %52.6 olarak bulundu. Hipertansiyonu olan ve ilaç kullanan 98 hastanın 29’unda (%29.5) kan basıncı kontrol altında değildi. Hipertansiyonu olanların yaşları ve vücut kütle indeksleri (VKİ), hipertansiyonu olmayanlara göre anlamlı olarak daha yüksekti (yaş için 63.2 ± 10.4’e karşın 55.3 ± 11.2, p <0.001; VKİ için 31.0 ± 6.8’e karşın 27.5 ± 5.6, p <0.001). Sigara içenlerin sıklığı hipertansiyonu olmayanlarda (%67.0), olanlara göre (%45.5) anlamlı olarak daha fazlaydı (p=0.004). Kreatinin düzeyi hipertansiyonu olan diyabetlilerde (1.2 ± 1.0), olmayanlara (1.0 ± 0.5) göre anlamlı olarak yüksek bulundu (p=0.038). Sonuç: Yatarak tedavi edilen tip 2 diyabetli hastalarda, yatış sırasında hipertansiyon sıklıkla eşlik edebilmektedir. Bu hastaların ise üçte birinde kan basınçları kontrol altında olmayıp bu durum diyabetle ilişkili komplikasyonlara olumsuz katkıda bulunabilir. Diyabeti olan bireylerde hipertansiyonun varlığı tespit edilmeli ve tedavisi mutlaka gözden geçirilmelidir. Anahtar Kelimeler: Tip 2 diyabetes mellitus, Hipertansiyon, Komplikasyon
目的:糖尿病和高血压是常见疾病,它们会增加彼此的风险,并可能引起心脏、血管和肾脏并发症。尽管人们经常研究门诊糖尿病患者的高血压患病率,但有关住院患者的资料却很有限。我们旨在调查住院糖尿病患者的高血压发病率。高血压的定义是至少两次在服用降压药或在医院测量的动脉血压高于 140/90 mmHg:住院的 2 型糖尿病患者中高血压患病率为 52.6%。在 98 名正在服药的高血压患者中,有 29 人(29.5%)的血压未得到控制。高血压患者的年龄和体重指数(BMI)明显高于非高血压患者(年龄为(63.2 ± 10.4)比(55.3 ± 11.2),P < 0.001;体重指数为(31.0 ± 6.8)比(27.5 ± 5.6),P < 0.001)。无高血压患者的吸烟率(67.0%)明显高于高血压患者(45.5%)(P=0.004)。患有高血压的糖尿病患者的肌酐水平(1.2 ± 1.0)明显高于无高血压患者(1.0 ± 0.5)(P=0.038)。结论在 2 型糖尿病住院患者中,高血压可能经常伴随住院。其中三分之一的患者血压未得到控制,这可能会对糖尿病相关并发症产生负面影响。应检测糖尿病患者是否患有高血压,并审查其治疗方法。关键词2型糖尿病 高血压 并发症
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引用次数: 0
Correlation of Morphometric Parameters Taken from the Head of the Mandible with Other Parameters of the Mandible 下颌骨头部形态计量学参数与其他参数的相关性
Pub Date : 2022-12-27 DOI: 10.35440/hutfd.1186395
Ş. Toy, Y. Secgin, D. Şenol, Zülal Öner, Abdullah Ray, Ismail Malkoç
Background: The mandible is a very important bone for forensic medicine, anthropology, anatomy and odontology sciences. This bone has many functions such as speaking, chewing and swallowing. This study was carried out to examine the relationship between morphometric parameters ob-tained from the head of the mandible and other parameters of the mandible.Materials and Methods: In our study, 45 dry mandible bones were used. These bones were photo-graphed and measured in the Image J program. These measurements were the distance of the head of the mandible to mental foramen (right, left), the distance of the head of the mandible to angle of the mandible (right, left), the distance of the head of the mandible to gnathion (right, left), the distance of the head of the mandible to coronoid process (right, left), the distance of the head of the mandible to the mandibular notch (right, left), the distance of the head of the mandible to alveolar juga (right, left) and the distance between right and left head of the mandible.Results: While no difference was found in terms of direction in dry mandibles with correlation anal-ysis (p>0.05), a high significant correlation was found in 18 parameters (p≤0.05).Conclusions: In our study, correlations were found between parameters obtained from the head of the mandible and other parameters of the mandible.
背景:下颌骨是法医学、人类学、解剖学和牙科学的重要研究对象。这块骨头有很多功能,比如说话、咀嚼和吞咽。本研究旨在探讨从下颌骨头部获得的形态测量参数与下颌骨其他参数之间的关系。材料与方法:本研究使用45块干下颌骨。这些骨头是在Image J程序中拍摄和测量的。这些测量头的距离的下颌骨颏孔(左,右)的距离的下颌骨角的下颌骨(左,右),头下颌骨颔下点的距离(左,右)的距离的下颌骨,喙突(左,右)的距离的下颌骨的下颌切口(左,右)的距离的下颌骨牙槽轭(对的,左)和左右头下颌骨之间的距离。结果:经相关分析,干性下颌骨在方向上无差异(p>0.05),但18个参数间存在高度显著相关(p≤0.05)。结论:在我们的研究中,从下颌骨头部获得的参数与下颌骨的其他参数之间存在相关性。
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引用次数: 0
İkinci Servikal Vertebranın Morfometrik Analizi: Radyolojik Bir Çalışma 第二颈椎的形态计量分析:放射学研究
Pub Date : 2022-12-27 DOI: 10.35440/hutfd.1208504
Sema Doğru, Sibel ATEŞOĞLU KARABAŞ, Tuğsan Ballı
Amaç: Baş ile gövde arasındaki bağlantıyı sağlayan servikal omurgalar kraniyofasial bir çok yapıyı barındıran önemli bir anatomik konuma sahiptir. Bu çalışmada yetişkin bireylerdeki ikinci servikal vertebranın (C-2) morfometrik özelliklerinin ortaya konulması ve cinsiyete bağlı farklılıkların belirlenmesi amaçlanmıştır. Materyal ve Metod: Çukurova Üniversitesi Radyoloji Anabilim dalına başvuran ve lateral kraniyofasiyal radyografisi çekilmiş 22 yaş ve üstü toplam 89 (40’ı kadın, 49’u erkek) hastada retrospektif olarak gerçekleştirilmiştir. Çalışmaya dahil edilen bireylerin yaşlarının ortalaması 47,85 (kadınlarda 48,15, erkeklerde 47,61) idi.Bulgular: Çalışmaya dahil edilen erkeklerin boy ve kilo ölçümlerinin kadınlardan daha yüksek olduğu belirlenmiştir (p<0,05). Ölçüm parametrelerine baktığımızda total yükseklik (TY), üst dens derinliği (ÜDD), alt dens derinliği (ADD), ön vertebra gövde yüksekliği (ÖVGY), arka vertebra gövde yüksekliği (AVGY) ve horizontal ön-arka uzunluklarının (HÖAU) erkeklerde kadınlardan istatistiksel olarak daha fazla olduğu görülmüştür (p<0,05).Sonuç: C-2 vertebranın morfometrik özellikleri ile kadın ve erkeklerdeki farklılıkları ortaya konulmuştur. Bu sonuçların göz önünde bulundurularak hastalıkların tanı ve tedavisinde, cerrahi operasyonlarda klinisyenlere yardımcı olabileceği kanaatindeyiz.
目的:颈椎是连接头部和躯干的重要部位,其解剖位置包括许多颅面结构。本研究旨在确定成人第二颈椎(C-2)的形态特征,并确定与性别相关的差异。材料和方法:本研究对Çukurova 大学放射科申请并接受颅颌面侧位放射摄影的 89 名 22 岁及以上患者(40 名女性和 49 名男性)进行了回顾性研究。研究对象的平均年龄为 47.85 岁(女性 48.15 岁,男性 47.61 岁):研究结果表明,男性的身高和体重测量值均高于女性(P<0.05)。从测量参数来看,男性的总身高(TH)、上椎体深度(ÜDD)、下椎体深度(ADD)、椎体前高度(ÖVGY)、椎体后高度(AVGY)和水平前后长度(HÖAU)均高于女性(P<0.05):结论:研究显示了 C-2 椎体的形态特征及其在男性和女性中的差异。我们相信,这些结果将有助于临床医生对疾病的诊断和治疗以及外科手术。
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引用次数: 0
Non-dipper ve Dipper Hipertansiyonlu Hastalardaki Copeptin Düzeyinin Karşılaştırması
Pub Date : 2022-12-27 DOI: 10.35440/hutfd.1141304
M. Altın, Halil Fedai̇, M. Erkuş, Özgür Günebakmaz
Amaç: Kardiyovasküler hastalıklar açısından hipertansiyon önemli bir risk faktörüdür. Amblatuvar kan basıncı monitörizasyonu(AKBM) ile yapılan çalışmalar kan basıncının gün içerisinde değiştiğini ve sirkadiyen bir ritminin olduğunu ortaya koymuştur. Kan basıncında gece % 10 veya daha fazla düşme olması dipper hipertansiyon (HT), olmaması non-dipper HT olarak nitelendirilmiştir. Non-dipper HT’li hastalarda kardiyovasküler riskin arttığı gösterilmiştir. Copeptin ise antidiüretik hormonun parçası olan bir molüküldür. Bazı çalışmalarda kardiyovasküler hastalıklar, serebrovasküler hastalıklar, sepsis ve şok gibi durumlarda kanda copeptin düzeyi hızlı bir yükseliş göstermektedir. Bu çalışmada dipper ve non-dipper hasta gruplarında serum copeptin düzeylerini karşılaştırmayı amaçladık. Materyal ve Metod: Bu çalışmaya yeni HT tanısı konulan 73 hasta çalışma grubu olarak ve 35 sağlıklı bireyde kontrol grubu olarak dahil edildi. HT tanısı konulan bireyler AKBM göre dipper HT ve non-dipper HT alt gruplarına ayrıldı. Çalışmaya alınan tüm bireylerin temel biyokimyasal parametreleri ve copeptin düzeyleri çalışıldı. Bulgular: Non-dipper HT'u olan bireylerin serum copeptin düzeyleri, hem kontrol hem dipper hasta grubuna göre serum copeptin düzeylerinden anlamlı olarak daha yüksek bulundu. İkili korolerasyon analizlerinde copeptin ile trigliserid arasında pozitif korelasyon görüldü. Diğer biyokimyasal belirteçler ile copeptin arasında istatistiksel olarak anlamlı bir ilişki bulunamadı. Sonuç: Serum copeptin düzeyleri prognoztik olarak kötü seyreden non-dipper hipertansif olan hasta grubunda yüksek saptandı. Bu bulgu artmış copeptin düzeyinin non-dipper HT’u olan hastaların prognozu ile ilişkili olduğunu düşündürmektedir. Bu nedenle copeptin düzeyi hipertansiyonlu hastalarda bir prognoztik parametre olarak kullanılabilir.
目的:高血压是心血管疾病的重要风险因素:高血压是心血管疾病的重要风险因素。使用动态血压监测(ABPM)进行的研究表明,血压在白天会发生变化,并有昼夜节律。夜间血压下降 10% 或更多被称为低血压(HT)和非低血压(HT)。研究表明,非自转性高血压患者的心血管风险会增加。copeptin 是抗利尿激素的一种分子。一些研究表明,在心血管疾病、脑血管疾病、败血症和休克等情况下,血液中的 copeptin 水平会迅速升高。在这项研究中,我们的目的是比较尿毒症患者组和非尿毒症患者组的血清 copeptin 水平。 材料和方法:在这项研究中,73 名新确诊的高血压患者被纳入研究组,35 名健康人被纳入对照组。根据 AKBM 将确诊的 HT 患者分为自吸型 HT 和非自吸型 HT 亚组。对所有研究对象的基本生化指标和 copeptin 水平进行分析。研究结果非自饮型高血压患者的血清 copeptin 水平明显高于对照组和自饮型高血压患者的血清 copeptin 水平。配对相关分析表明, copeptin 与甘油三酯之间存在正相关。在统计学上,未发现 copeptin 与其他生化指标之间有明显的相关性。结论血清 copeptin 水平在预后不良的非糖尿病高血压患者中升高。这一发现表明, copeptin 水平升高与非自转高血压患者的预后有关。因此, copeptin 水平可用作高血压患者的预后参数。
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引用次数: 0
Brain MRI Findings In Children With Convulsions Secondary to Covid-19 Infection Covid-19感染继发惊厥儿童的脑MRI表现
Pub Date : 2022-12-27 DOI: 10.35440/hutfd.1201798
F. Doğan, Mehmet Zeki Yilmazteki̇n
Background: The aim of the current study was to investigate magnetic resonance imaging (MRI) findings in children who developed convulsions after COVID-19 infection.Materials and Methods: A retrospective screening was made of paediatric cases who presented at the COVID-19 pandemic clinic with suspected COVID-19 infection between March 2020 and June 2021 and were diagnosed with COVID-19 from a positive real-time polymerase chain reaction test (qRT-PCR). Non-contrast brain and diffusion MRI performed using a 3-Tesla device in all patients with convulsions. The demographic characteristics and brain MRI findings were recorded of cases with COVID-19 infection who developed convulsions.Results: Evaluation was made of 6 cases who were diagnosed with COVID-19 and developed convulsions during the disease course. There was a history of convulsions in 3 patients and recurrent convulsion attacks developed despite anticonvulsant therapy. In the other 3 cases developed convulsion, there was no history of convulsions, or additional disease. Non-contrast brain MRI was taken for etiology in all patients. In all the cases, no signal changes of acute pathologies were detected on diffusion MRI.Conclusion: COVID-19 infection can trigger convulsions even in patients with epilepsy and taking anticonvulsant therapy and may cause convulsions in previously healthy cases. Unlike in the adult patient population, COVID-19 infection was not seen to cause acute changes in brain MRI findings in the pediatric age group who developed convulsions due to COVID-19 infection.
背景:本研究的目的是调查COVID-19感染后发生惊厥的儿童的磁共振成像(MRI)结果。材料与方法:回顾性筛选2020年3月至2021年6月期间在COVID-19大流行诊所就诊的疑似COVID-19感染的儿科病例,并通过实时聚合酶链反应试验(qRT-PCR)阳性诊断为COVID-19。所有惊厥患者均使用3特斯拉设备进行非对比脑和弥散MRI。记录发生惊厥的COVID-19感染病例的人口学特征和脑MRI结果。结果:对6例确诊为COVID-19并在病程中出现惊厥的患者进行评估。3例患者有惊厥病史,经抗惊厥药物治疗后仍发生反复惊厥发作。其余3例发生惊厥,无惊厥史,无其他疾病。所有患者均行非对比脑MRI检查病因。所有病例弥散MRI未见急性病变信号改变。结论:COVID-19感染即使在癫痫患者和服用抗惊厥药物的患者中也可引发惊厥,并且可能在先前健康的病例中引起惊厥。与成人患者群体不同,在因COVID-19感染而出现抽搐的儿科年龄组中,COVID-19感染未引起脑MRI结果的急性变化。
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引用次数: 0
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Harran Üniversitesi Tıp Fakültesi Dergisi
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