Pub Date : 2024-03-30DOI: 10.15584/ejcem.2024.1.14
A. Ojoawo, Oluwaseun Odesanya, Kayode Kunuji, C. Mbada, Oluwafemi Olusesan Adedeji
Introduction and aim. The study assessed and compared the effects of clinic-based and telemonitored home-based interventions on pain intensity, functioning and quality of life in patients with knee osteoarthritis (KOA). Material and methods. Forty-two patients were recruited purposely and randomly allocated into clinic-based (CBG) and telemonitored home-based group (THG) equally. The CBG and THG received isometric exercises to strengthen the quadriceps and hamstring muscles using theraband. THG received the exercise at home they were monitored on phone thrice in a week, while the CBG did the exercise in the hospital. The subjects performed four sets of eight repetitions three days in a week for eight weeks. Pain intensity, functioning and health related quality of life (HRQoL) were assessed at pretreatment, 6th and 8th week of intervention. Data was analyzed with descriptive and inferential statistics. Alpha level was set at 0.05. Results. There was a significant reduction (p<0.001) among pre-treatment, 6th and 8th week intervention in pain intensity, functional pain intensity and quality of life of CBG and THG. CBG showed significant reduction (p<0.001) in pain intensity, function and increase in HRQoL than THG at 8th week. Conclusion. Clinic-based and telemonitored home-based interventions were both effective in the management of KOA but clinic-based intervention was better than telemonitored home-based intervention.
{"title":"Effect of clinic-based and telemonitored home-based intervention on pain intensity, functioning and quality of life in patients with knee osteoarthritis","authors":"A. Ojoawo, Oluwaseun Odesanya, Kayode Kunuji, C. Mbada, Oluwafemi Olusesan Adedeji","doi":"10.15584/ejcem.2024.1.14","DOIUrl":"https://doi.org/10.15584/ejcem.2024.1.14","url":null,"abstract":"Introduction and aim. The study assessed and compared the effects of clinic-based and telemonitored home-based interventions on pain intensity, functioning and quality of life in patients with knee osteoarthritis (KOA). Material and methods. Forty-two patients were recruited purposely and randomly allocated into clinic-based (CBG) and telemonitored home-based group (THG) equally. The CBG and THG received isometric exercises to strengthen the quadriceps and hamstring muscles using theraband. THG received the exercise at home they were monitored on phone thrice in a week, while the CBG did the exercise in the hospital. The subjects performed four sets of eight repetitions three days in a week for eight weeks. Pain intensity, functioning and health related quality of life (HRQoL) were assessed at pretreatment, 6th and 8th week of intervention. Data was analyzed with descriptive and inferential statistics. Alpha level was set at 0.05. Results. There was a significant reduction (p<0.001) among pre-treatment, 6th and 8th week intervention in pain intensity, functional pain intensity and quality of life of CBG and THG. CBG showed significant reduction (p<0.001) in pain intensity, function and increase in HRQoL than THG at 8th week. Conclusion. Clinic-based and telemonitored home-based interventions were both effective in the management of KOA but clinic-based intervention was better than telemonitored home-based intervention.","PeriodicalId":11828,"journal":{"name":"European Journal of Clinical and Experimental Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140361752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-30DOI: 10.15584/ejcem.2024.1.21
N. Stepanova, A. Rysyev, L. Snisar
Introduction and aim. Long-term outcomes of COVID-19 pose a global challenge, particularly impacting individuals with un derlying health conditions, including those who have undergone hemodialysis (HD). The study aimed to investigate the rela tionship between preexisting dialysis dose, measured by single pool Kt/V (spKt/V), and long-term outcomes of COVID-19 in patients undergoing HD. Material and methods. Demographic, clinical, and laboratory parameters following COVID-19 recovery, and long-term out comes, including the presence of COVID-19 sequelae, hospitalization, and all-cause mortality during a year after COVID-19 were retrospectively analyzed. Results. Out of the 195 patients included, there were 108 males (55.4%) and 87 females (44.6%), with a median age of 56 (44-63) years and a dialysis duration of 49 (31.3–85.2) months. Patients with spKt/V<1.4 had a significantly increased risk of long-term COVID-19 sequelae (HR 9.1, 95% CI: 3.4; 24.6), hospitalization (HR 7.6, 95% CI: 3.9; 14.6), and all-cause mortality (HR 8.5, 95% CI: 2.9; 25.8) within one year after COVID-19 recovery compared with those with spKt/V≥1.4. spKt/V cutoff point of ≤1.3 emerged as a significant risk factor for one-year hospitalization and mortality within our cohort. Conclusion. Suboptimal dialysis dose, as indicated by spKt/V < 1.4, is associated with adverse long-term COVID-19 outcomes in patients undergoing HD. Optimizing dialysis adequacy may mitigate these risks. Further research is needed to validate these f indings and explore interventions to improve outcomes in this vulnerable population.
{"title":"Hemodialysis dose and long-term COVID-19 outcomes – a retrospective cohort study","authors":"N. Stepanova, A. Rysyev, L. Snisar","doi":"10.15584/ejcem.2024.1.21","DOIUrl":"https://doi.org/10.15584/ejcem.2024.1.21","url":null,"abstract":"Introduction and aim. Long-term outcomes of COVID-19 pose a global challenge, particularly impacting individuals with un derlying health conditions, including those who have undergone hemodialysis (HD). The study aimed to investigate the rela tionship between preexisting dialysis dose, measured by single pool Kt/V (spKt/V), and long-term outcomes of COVID-19 in patients undergoing HD. Material and methods. Demographic, clinical, and laboratory parameters following COVID-19 recovery, and long-term out comes, including the presence of COVID-19 sequelae, hospitalization, and all-cause mortality during a year after COVID-19 were retrospectively analyzed. Results. Out of the 195 patients included, there were 108 males (55.4%) and 87 females (44.6%), with a median age of 56 (44-63) years and a dialysis duration of 49 (31.3–85.2) months. Patients with spKt/V<1.4 had a significantly increased risk of long-term COVID-19 sequelae (HR 9.1, 95% CI: 3.4; 24.6), hospitalization (HR 7.6, 95% CI: 3.9; 14.6), and all-cause mortality (HR 8.5, 95% CI: 2.9; 25.8) within one year after COVID-19 recovery compared with those with spKt/V≥1.4. spKt/V cutoff point of ≤1.3 emerged as a significant risk factor for one-year hospitalization and mortality within our cohort. Conclusion. Suboptimal dialysis dose, as indicated by spKt/V < 1.4, is associated with adverse long-term COVID-19 outcomes in patients undergoing HD. Optimizing dialysis adequacy may mitigate these risks. Further research is needed to validate these f indings and explore interventions to improve outcomes in this vulnerable population.","PeriodicalId":11828,"journal":{"name":"European Journal of Clinical and Experimental Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140362324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-30DOI: 10.15584/ejcem.2024.1.23
R. Maalman, S. Bimpong, C. Abaidoo, Magalys Lopez Cuba, Michael Barima Kumi, Francis Kofi Sarkodie
Introduction and aim. There has been a surge in the consumption of Ghanaian alcoholic bitters. Ghanaian alcoholic bitters are formulated from a maceration of not less than three plant parts making the organic composition very complex. There appear to be no studies on the effect of Ghanaian alcoholic bitters on the hepatorenal biochemistry indices. The study aimed to assess the effects of alcoholic bitters and cocoa powder on the liver and kidney serum biochemistry. Material and methods. Twenty-four healthy male Sprague Dawley rats, age 11–12 weeks, weighing 150–250 g were used. The rats were randomly assigned to four groups (n=6). At the end of the experimentation, a blood sample was taken by cardiac puncture and centrifuged to obtain the serum for biochemical assays and analysis. Results. The liver enzymes showed no significant difference between the treatment and control groups. There were higher mean values for total bilirubin and direct bilirubin for alcoholic bitters and natural cocoa powder groups respectively than the control group and the co-administration of alcoholic bitters and natural cocoa powder group. Conclusion. The study concludes that alcoholic bitters consumption might cause injury to the liver and kidney resulting in anomaly of the hepatorenal indices from rat blood serum biochemistry.
{"title":"Assessment of hepatorenal biochemical indices in male Sprague Dawley rats preceding concurrent oral administration of Ghana alcoholic bitters and natural cocoa powder","authors":"R. Maalman, S. Bimpong, C. Abaidoo, Magalys Lopez Cuba, Michael Barima Kumi, Francis Kofi Sarkodie","doi":"10.15584/ejcem.2024.1.23","DOIUrl":"https://doi.org/10.15584/ejcem.2024.1.23","url":null,"abstract":"Introduction and aim. There has been a surge in the consumption of Ghanaian alcoholic bitters. Ghanaian alcoholic bitters are formulated from a maceration of not less than three plant parts making the organic composition very complex. There appear to be no studies on the effect of Ghanaian alcoholic bitters on the hepatorenal biochemistry indices. The study aimed to assess the effects of alcoholic bitters and cocoa powder on the liver and kidney serum biochemistry. Material and methods. Twenty-four healthy male Sprague Dawley rats, age 11–12 weeks, weighing 150–250 g were used. The rats were randomly assigned to four groups (n=6). At the end of the experimentation, a blood sample was taken by cardiac puncture and centrifuged to obtain the serum for biochemical assays and analysis. Results. The liver enzymes showed no significant difference between the treatment and control groups. There were higher mean values for total bilirubin and direct bilirubin for alcoholic bitters and natural cocoa powder groups respectively than the control group and the co-administration of alcoholic bitters and natural cocoa powder group. Conclusion. The study concludes that alcoholic bitters consumption might cause injury to the liver and kidney resulting in anomaly of the hepatorenal indices from rat blood serum biochemistry.","PeriodicalId":11828,"journal":{"name":"European Journal of Clinical and Experimental Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140364503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction and aim. Global and national care recommendations indicate that women with high-risk pregnancies should receive personalized and qualified care during this period. This study was conducted to determine the distress levels in high-risk pregnant women and affecting factors. Material and methods. The cross-sectional this study was conducted with total of 416 high-risk pregnant women who met the inclusion criteria in the obstetrics clinic of a training and research hospital. The study data were collected with data collection form and “Tilburg Pregnancy Distress Scale (TPDS).” Results. The mean TPDS total score of high-risk pregnant women was 18.25±6.85. It was found that planning pregnancy, gravida, and diagnosis of gestational hypertension, systemic diseases, and gestational diabetes in the present pregnancy was asso ciated with pregnancy-specific distress (p<0.05; β=0.291, β=0.158, β=0.272, β=0.137, β=0.116, respectively). Conclusion. It is advised that health professionals assess the distress levels of high-risk pregnant women and give personalized care during prenatal period.
{"title":"Determinants of distress levels in high-risk pregnant women – cross-sectional study","authors":"Pınar Kara, Evşen Nazik, Zehra Çerçer","doi":"10.15584/ejcem.2024.1.9","DOIUrl":"https://doi.org/10.15584/ejcem.2024.1.9","url":null,"abstract":"Introduction and aim. Global and national care recommendations indicate that women with high-risk pregnancies should receive personalized and qualified care during this period. This study was conducted to determine the distress levels in high-risk pregnant women and affecting factors. Material and methods. The cross-sectional this study was conducted with total of 416 high-risk pregnant women who met the inclusion criteria in the obstetrics clinic of a training and research hospital. The study data were collected with data collection form and “Tilburg Pregnancy Distress Scale (TPDS).” Results. The mean TPDS total score of high-risk pregnant women was 18.25±6.85. It was found that planning pregnancy, gravida, and diagnosis of gestational hypertension, systemic diseases, and gestational diabetes in the present pregnancy was asso ciated with pregnancy-specific distress (p<0.05; β=0.291, β=0.158, β=0.272, β=0.137, β=0.116, respectively). Conclusion. It is advised that health professionals assess the distress levels of high-risk pregnant women and give personalized care during prenatal period.","PeriodicalId":11828,"journal":{"name":"European Journal of Clinical and Experimental Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140364665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction and aim. In patients with schizophrenia, omega-3 (n-3) polyunsaturated fatty acids (PUFAs) treatment was found to ameliorate the cardiovascular, metabolic, and inflammatory problems caused by antipsychotic medication and even reduce the need for medication by 20%. In this study, we evaluated the potential therapeutic effects of n-3 PUFA supplementation in patients with schizophrenia. Material and methods. The PRISMA guidelines were followed in conducting this systematic review. The Embase, MEDLINE, Web of Science, and Google Scholar databases were searched electronically. The first search yielded 50 papers in total. Subse quently, 43 publications that did not meet our eligibility requirements were removed, and seven articles were selected. Analysis of the literature. The analysis showed that n-3 PUFA supplementation and the placebo group both decreased their psychotic (PANSS and GAF scales) and Calgary Depression Scale symptomatology and boosted their functional ability (GAF) when used as an adjuvant to antipsychotic medication. When administered as a monotherapy with a metabolic antioxidant, n-3 PUFA supplementation proved beneficial for treating schizophrenia. In patients with schizophrenia, n-3 PUFAs have thera peutic benefits as adjuvant treatments to medications, although not for different variables or patient groups. Conclusion. In many studies, patients with chronic schizophrenia who received n-3 PUFA supplementation showed no improvement in their clinical condition.
{"title":"Therapeutic advantages of omega-3 fatty acid supplementation in patients with schizophrenia – a systematic review","authors":"Srilaxmi Vityala, Krishna Priya Kanteti, Yethindra Vityala, T. Tagaev, Ujwala Damineni","doi":"10.15584/ejcem.2024.1.5","DOIUrl":"https://doi.org/10.15584/ejcem.2024.1.5","url":null,"abstract":"Introduction and aim. In patients with schizophrenia, omega-3 (n-3) polyunsaturated fatty acids (PUFAs) treatment was found to ameliorate the cardiovascular, metabolic, and inflammatory problems caused by antipsychotic medication and even reduce the need for medication by 20%. In this study, we evaluated the potential therapeutic effects of n-3 PUFA supplementation in patients with schizophrenia. Material and methods. The PRISMA guidelines were followed in conducting this systematic review. The Embase, MEDLINE, Web of Science, and Google Scholar databases were searched electronically. The first search yielded 50 papers in total. Subse quently, 43 publications that did not meet our eligibility requirements were removed, and seven articles were selected. Analysis of the literature. The analysis showed that n-3 PUFA supplementation and the placebo group both decreased their psychotic (PANSS and GAF scales) and Calgary Depression Scale symptomatology and boosted their functional ability (GAF) when used as an adjuvant to antipsychotic medication. When administered as a monotherapy with a metabolic antioxidant, n-3 PUFA supplementation proved beneficial for treating schizophrenia. In patients with schizophrenia, n-3 PUFAs have thera peutic benefits as adjuvant treatments to medications, although not for different variables or patient groups. Conclusion. In many studies, patients with chronic schizophrenia who received n-3 PUFA supplementation showed no improvement in their clinical condition.","PeriodicalId":11828,"journal":{"name":"European Journal of Clinical and Experimental Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140363398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction and aim. The effective and safe administration of medication is the responsibility of every health care provider involved in patient care. One of the biggest problems with nursing education is the gap between theory and practice, which pave ways for medication errors to occur at any level of the medication administration process. This can be rectified by using an efficient teaching strategy that harmoniously blends nursing theory and practical skills. the aim of the study was to evaluate the effectiveness of the traditional teaching method versus simulation-based teaching method on level of knowledge, attitude, and practice on prevention of medication errors among nursing students in selected colleges, Puducherry. Material and methods. The research approach and design used for the study were quantitative approach and quasi-experi mental pre and post-test control group design respectively. The study settings were selected 4 nursing colleges in Puducherry. The sample size was 100 (50 in experimental group I and 50 in experimental group II) which was selected by using simple ran dom and stratified sampling technique. pre-test was done to assess the level of knowledge, attitude and practice on preven tion of medication error for both experimental groups utilizing the self-administered knowledge, attitude questionnaire and checklist. The experimental group I received traditional teaching method and experimental group II received simulation-based teaching method. Post-test was done after one week using the same tool. Results. The study results revealed that out of 100 nursing students, majority 35 (70%) and 38 (76%) of the nursing students were in the age group of 20–21 years, 40 (80%) and 39 (78%) of them were female, 50 (100%) and 41 (82%) of them were staying as day scholars, 40 (80%) and 41 (82%) had one attempt to clear the pharmacology subject in the experimental group I and II respectively. The level of knowledge, attitude, practice showed a statistically significance difference at p<0.05 between the pre and post-test within the experimental group I and II respectively. The effective mean scores of knowledge, attitude and practice showed a statistically significance difference at p<0.05 between the experimental group I and II respectively, revealed that the simulation-based teaching method was more effective over the traditional teaching method. There was a significant positive correlation at p<0.05 exist between the level of knowledge and attitude, knowledge and practice in the experimental group I. The association between the post-test level of attitude and the gender variable showed a statistically significant at p<0.05 in the experimental group II. Conclusion. The study concluded that the simulation-based teaching method was effective which can be utilized as a means to educate the nursing students during their academic performance.
引言和目的。有效、安全地用药是每一位参与患者护理的医护人员的责任。护理教育的最大问题之一是理论与实践之间的差距，这为用药过程中任何环节出现用药错误铺平了道路。本研究旨在评估传统教学法与模拟教学法对普度克里选定学院护理专业学生预防用药错误的知识、态度和实践水平的影响。材料和方法。本研究采用的研究方法和设计分别为定量方法和准前瞻性前后对照组设计。研究地点选在普杜切里的 4 所护理学院。样本量为 100 个（实验 I 组 50 个，实验 II 组 50 个），采用简单抽样和分层抽样技术。实验 I 组采用传统教学法，实验 II 组采用模拟教学法。一周后使用相同的工具进行后测。结果显示研究结果显示，在 100 名护理专业学生中，35 名（70%）和 38 名（76%）护理专业学生的年龄在 20-21 岁之间，40 名（80%）和 39 名（78%）为女生，50 名（100%）和 41 名（82%）为走读生，40 名（80%）和 41 名（82%）分别在实验组 I 和实验组 II 中尝试过一次药理学课程。实验组 I 和实验组 II 的知识、态度和实践水平在前测和后测之间的差异（P<0.05）具有统计学意义。实验组 I 和实验组 II 的知识、态度和实践的有效平均分分别在 P<0.05 时有显著的统计学差异，这表明模拟教学法比传统教学法更有效。实验组 I 的知识水平与态度、知识与实践之间存在明显的正相关（P<0.05）。结论该研究得出结论，模拟教学法是有效的，可以作为一种手段在护理专业学生的学业成绩中对其进行教育。
{"title":"Traditional teaching method versus simulation-based teaching method in the prevention of medication errors among nursing students","authors":"Rohini Ramamurthy, Felicia Chitra, Kavitha","doi":"10.15584/ejcem.2024.1.2","DOIUrl":"https://doi.org/10.15584/ejcem.2024.1.2","url":null,"abstract":"Introduction and aim. The effective and safe administration of medication is the responsibility of every health care provider involved in patient care. One of the biggest problems with nursing education is the gap between theory and practice, which pave ways for medication errors to occur at any level of the medication administration process. This can be rectified by using an efficient teaching strategy that harmoniously blends nursing theory and practical skills. the aim of the study was to evaluate the effectiveness of the traditional teaching method versus simulation-based teaching method on level of knowledge, attitude, and practice on prevention of medication errors among nursing students in selected colleges, Puducherry. Material and methods. The research approach and design used for the study were quantitative approach and quasi-experi mental pre and post-test control group design respectively. The study settings were selected 4 nursing colleges in Puducherry. The sample size was 100 (50 in experimental group I and 50 in experimental group II) which was selected by using simple ran dom and stratified sampling technique. pre-test was done to assess the level of knowledge, attitude and practice on preven tion of medication error for both experimental groups utilizing the self-administered knowledge, attitude questionnaire and checklist. The experimental group I received traditional teaching method and experimental group II received simulation-based teaching method. Post-test was done after one week using the same tool. Results. The study results revealed that out of 100 nursing students, majority 35 (70%) and 38 (76%) of the nursing students were in the age group of 20–21 years, 40 (80%) and 39 (78%) of them were female, 50 (100%) and 41 (82%) of them were staying as day scholars, 40 (80%) and 41 (82%) had one attempt to clear the pharmacology subject in the experimental group I and II respectively. The level of knowledge, attitude, practice showed a statistically significance difference at p<0.05 between the pre and post-test within the experimental group I and II respectively. The effective mean scores of knowledge, attitude and practice showed a statistically significance difference at p<0.05 between the experimental group I and II respectively, revealed that the simulation-based teaching method was more effective over the traditional teaching method. There was a significant positive correlation at p<0.05 exist between the level of knowledge and attitude, knowledge and practice in the experimental group I. The association between the post-test level of attitude and the gender variable showed a statistically significant at p<0.05 in the experimental group II. Conclusion. The study concluded that the simulation-based teaching method was effective which can be utilized as a means to educate the nursing students during their academic performance.","PeriodicalId":11828,"journal":{"name":"European Journal of Clinical and Experimental Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140361306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-30DOI: 10.15584/ejcem.2024.1.11
Igor Gawłowski, Joanna Ożga, Agata Raczko
Introduction and aim. Artificial intelligence is increasingly being used in the medicine, particularly in radiological diagnosis of diseases such as an axial spondyloarthritis (axSpA). The aim of this study is to compare the available algorithms designed to detect active sacroiliitis in patients with axSpA. Material and methods. Four algorithms, two semi-automated and two full-automated for the assessment of bone marrow ede ma (BME) on magnetic resonance imaging (MRI) of the sacroiliac joints (SIJs) were included in the study. They were described and compared in terms of specificity, sensitivity, and correlation of BME detection findings between AI and experts. Analysis of the literature. Among all automated algorithms, the one created by Bressem et al. had the highest number of ex aminations analyzed in the study, involving 593 MRIs of SIJs. The sensitivity and specificity, as well as the correlation between the AI’s detection of BME versus manual, were not calculated for each algorithm. Rzecki’s algorithm had the greatest sensitivity and specificity for BME detection reaching 0.95 and 0.96, respectively. In addition, its Speraman’s coefficient of correlation be tween manual and automated measurements was 0.866. Conclusion. Each of described algorithms is certainly useful in assessing BME in the MRI examinations of SIJs.
{"title":"Comparison of algorithms for detection of active inflammatory lesions in sacroiliitis","authors":"Igor Gawłowski, Joanna Ożga, Agata Raczko","doi":"10.15584/ejcem.2024.1.11","DOIUrl":"https://doi.org/10.15584/ejcem.2024.1.11","url":null,"abstract":"Introduction and aim. Artificial intelligence is increasingly being used in the medicine, particularly in radiological diagnosis of diseases such as an axial spondyloarthritis (axSpA). The aim of this study is to compare the available algorithms designed to detect active sacroiliitis in patients with axSpA. Material and methods. Four algorithms, two semi-automated and two full-automated for the assessment of bone marrow ede ma (BME) on magnetic resonance imaging (MRI) of the sacroiliac joints (SIJs) were included in the study. They were described and compared in terms of specificity, sensitivity, and correlation of BME detection findings between AI and experts. Analysis of the literature. Among all automated algorithms, the one created by Bressem et al. had the highest number of ex aminations analyzed in the study, involving 593 MRIs of SIJs. The sensitivity and specificity, as well as the correlation between the AI’s detection of BME versus manual, were not calculated for each algorithm. Rzecki’s algorithm had the greatest sensitivity and specificity for BME detection reaching 0.95 and 0.96, respectively. In addition, its Speraman’s coefficient of correlation be tween manual and automated measurements was 0.866. Conclusion. Each of described algorithms is certainly useful in assessing BME in the MRI examinations of SIJs.","PeriodicalId":11828,"journal":{"name":"European Journal of Clinical and Experimental Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140361613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction and aim. With the development of transportation facilities and options, people can now travel easily. With women having a greater presence in the workforce, pregnant women can work until the eighth week before childbirth. This study was conducted to examine the behaviors of pregnant women regarding travel. Material and methods. The data for this cross-sectional and descriptive study were collected from 519 pregnant women who voluntarily participated in the research and met the research criteria. The data were analyzed using the SPSS 24 software package. Results. The average age of the participating pregnant women was 27.49±0.17, with 63.8% residing in urban areas, 74.8% be ing primiparous, and 47.6% being in the third trimester of pregnancy. A decrease in travel and car usage during pregnancy. The use of bus, train/tram/metro, taxi, bicycle/scooter, and motorcycle decreased during pregnancy, while use of car, plane, and ship/ferry increased. 81.9% of women always wore a seat belt during pregnancy. There was a statistically significant difference between the educational level of women and their car usage (p<0.005). It was found that women wore seat belts more frequently in the third trimester. As the number of pregnancies increased, the frequency of seat belt usage decreased. Conclusion. A decrease in the frequency of travel was observed among women during pregnancy. The levels of seat belt usage and correct seat belt fastening were unsatisfactory.
{"title":"Behaviors of pregnant women regarding travel – the case of Türkiye","authors":"Şeyma Kilci Erciyas, Ebru Cirban Ekrem Cirban-Ekrem, Rukiye Demir, Gizem Aköz","doi":"10.15584/ejcem.2024.1.7","DOIUrl":"https://doi.org/10.15584/ejcem.2024.1.7","url":null,"abstract":"Introduction and aim. With the development of transportation facilities and options, people can now travel easily. With women having a greater presence in the workforce, pregnant women can work until the eighth week before childbirth. This study was conducted to examine the behaviors of pregnant women regarding travel. Material and methods. The data for this cross-sectional and descriptive study were collected from 519 pregnant women who voluntarily participated in the research and met the research criteria. The data were analyzed using the SPSS 24 software package. Results. The average age of the participating pregnant women was 27.49±0.17, with 63.8% residing in urban areas, 74.8% be ing primiparous, and 47.6% being in the third trimester of pregnancy. A decrease in travel and car usage during pregnancy. The use of bus, train/tram/metro, taxi, bicycle/scooter, and motorcycle decreased during pregnancy, while use of car, plane, and ship/ferry increased. 81.9% of women always wore a seat belt during pregnancy. There was a statistically significant difference between the educational level of women and their car usage (p<0.005). It was found that women wore seat belts more frequently in the third trimester. As the number of pregnancies increased, the frequency of seat belt usage decreased. Conclusion. A decrease in the frequency of travel was observed among women during pregnancy. The levels of seat belt usage and correct seat belt fastening were unsatisfactory.","PeriodicalId":11828,"journal":{"name":"European Journal of Clinical and Experimental Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140363108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-30DOI: 10.15584/ejcem.2024.1.22
Nataliia Demianchuk, Viorika Akimova, Larysa Soyka, M. Shchurko, Lyubov Lapovets, N. Lutsiv, Serhii Tkachuk, Olha Buchko, Svitlana Zubchenko, Ihor Hayduchok
Introduction and aim. Information concerning lactoferrin and interleukin-8 (IL-8) local levels in breast milk are not numerous and requires further research. The aim of this study was to determine the content of lactoferrin and interleukin-8 in the breast milk of patients with lactational mastitis, and to identify new potential markers for assessing the activity of the inflammatory process in the mammary gland. Material and methods. This study analyzed the breast milk of 30 women with lactostasis (group I), 37 women with lactational mastitis (group II) and 30 healthy lactating women (age 26±5 years old). The milk content of lactoferrin and interleukin-8 (IL-8) was determined by enzyme-linked immunosorbent assay. Results. The average value of lactoferrin in breast milk of healthy women was 4.78±0.47 mg/mL, exceeding levels in group I 1.8 times (p<0.05). The level of lactoferrin in group II exceeds the control values 3.1 times (p<0.05). The content of IL-8 in breast milk of women in group I was 7.3 times higher than the control (3.63±0.12 pg/mL, p<0.05). In lactational mastitis, the concentration of IL-8 in breast milk exceeded the group I 13.9 times (p<0.05) and was 1.9 times higher than group I (p<0.05). Conclusion. The analysis has revealed an increase of lactoferrin and IL-8 in breast milk of the test groups, which indicates the activation of non-specific protection.
{"title":"The content of lactoferrin and interleukin-8 in breast milk of patients with lactational mastitis","authors":"Nataliia Demianchuk, Viorika Akimova, Larysa Soyka, M. Shchurko, Lyubov Lapovets, N. Lutsiv, Serhii Tkachuk, Olha Buchko, Svitlana Zubchenko, Ihor Hayduchok","doi":"10.15584/ejcem.2024.1.22","DOIUrl":"https://doi.org/10.15584/ejcem.2024.1.22","url":null,"abstract":"Introduction and aim. Information concerning lactoferrin and interleukin-8 (IL-8) local levels in breast milk are not numerous and requires further research. The aim of this study was to determine the content of lactoferrin and interleukin-8 in the breast milk of patients with lactational mastitis, and to identify new potential markers for assessing the activity of the inflammatory process in the mammary gland. Material and methods. This study analyzed the breast milk of 30 women with lactostasis (group I), 37 women with lactational mastitis (group II) and 30 healthy lactating women (age 26±5 years old). The milk content of lactoferrin and interleukin-8 (IL-8) was determined by enzyme-linked immunosorbent assay. Results. The average value of lactoferrin in breast milk of healthy women was 4.78±0.47 mg/mL, exceeding levels in group I 1.8 times (p<0.05). The level of lactoferrin in group II exceeds the control values 3.1 times (p<0.05). The content of IL-8 in breast milk of women in group I was 7.3 times higher than the control (3.63±0.12 pg/mL, p<0.05). In lactational mastitis, the concentration of IL-8 in breast milk exceeded the group I 13.9 times (p<0.05) and was 1.9 times higher than group I (p<0.05). Conclusion. The analysis has revealed an increase of lactoferrin and IL-8 in breast milk of the test groups, which indicates the activation of non-specific protection.","PeriodicalId":11828,"journal":{"name":"European Journal of Clinical and Experimental Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140362282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-30DOI: 10.15584/ejcem.2024.1.26
Martyna Dyrek, Ewa Sikorska, Aleksandra Partyka, Piotr Sikorski, Edyta Dusza, Dorota Kopacz
Introduction and aim. Recently, an increased use of video display terminals has been observed in workplace environments, as a result of the evolution of communication technologies and new information-sharing strategies. It has led to an increased prevalence of computer-related ocular disorders, such as computer vision syndrome, dry eye disease, refractive errors and con vergence insufficiency. In this review we describe problems associated with these disorders and propose preventive methods. Material and methods. With the use of specific keywords, the databases of the PubMed, Science Direct, and Google Scholar were searched for relevant original papers. Analysis of the literature. The listed disorders might have similar symptoms, such as eye burning, itching, blurred vision, and tearing, and their severity correlates with the time of exposure to video display units. However, there are preventive measures, which can help in decreasing the negative effects of computers on our vision, such as adequate viewing distance, proper work space lighting, eyeglasses with anti-glare coating, taking 5-minutes breaks after every 30 minutes, or following the 20-20-20 rule. Conclusion. Prolonged usage of the video display terminals is connected to many ocular disorders, and in today’s world, it is very important to remember actions that can be undertaken to minimize the risk.
导言和目的。近来，由于通信技术的发展和新的信息共享策略，视频显示终端在工作环境中的使用越来越多。计算机视觉综合症、干眼症、屈光不正和辐辏不全等与计算机有关的眼部疾病的发病率也随之上升。在这篇综述中，我们描述了与这些疾病相关的问题，并提出了预防方法。材料和方法。使用特定的关键词，在 PubMed、Science Direct 和 Google Scholar 数据库中搜索相关的原始论文。文献分析。所列疾病可能有类似的症状，如眼睛灼热、发痒、视力模糊和流泪，其严重程度与接触视频显示设备的时间相关。不过，有一些预防措施可以帮助减少电脑对视力的负面影响，如足够的观看距离、适当的工作空间照明、带防眩光涂层的眼镜、每 30 分钟休息 5 分钟，或遵循 20-20-20 原则。结论长时间使用视频显示终端与许多眼部疾病有关，在当今世界，记住可以采取的措施以尽量减少风险是非常重要的。
{"title":"Prolonged screen-time as the cause of ocular disorders: what can we do with the problem? – a review","authors":"Martyna Dyrek, Ewa Sikorska, Aleksandra Partyka, Piotr Sikorski, Edyta Dusza, Dorota Kopacz","doi":"10.15584/ejcem.2024.1.26","DOIUrl":"https://doi.org/10.15584/ejcem.2024.1.26","url":null,"abstract":"Introduction and aim. Recently, an increased use of video display terminals has been observed in workplace environments, as a result of the evolution of communication technologies and new information-sharing strategies. It has led to an increased prevalence of computer-related ocular disorders, such as computer vision syndrome, dry eye disease, refractive errors and con vergence insufficiency. In this review we describe problems associated with these disorders and propose preventive methods. Material and methods. With the use of specific keywords, the databases of the PubMed, Science Direct, and Google Scholar were searched for relevant original papers. Analysis of the literature. The listed disorders might have similar symptoms, such as eye burning, itching, blurred vision, and tearing, and their severity correlates with the time of exposure to video display units. However, there are preventive measures, which can help in decreasing the negative effects of computers on our vision, such as adequate viewing distance, proper work space lighting, eyeglasses with anti-glare coating, taking 5-minutes breaks after every 30 minutes, or following the 20-20-20 rule. Conclusion. Prolonged usage of the video display terminals is connected to many ocular disorders, and in today’s world, it is very important to remember actions that can be undertaken to minimize the risk.","PeriodicalId":11828,"journal":{"name":"European Journal of Clinical and Experimental Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140364692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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