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HİPOKSİK İSKEMİK ENSEFALOPATİDE UMBLİKAL KORD PH VE İZLEMDE ALINAN KARDİYAK BELİRTEÇLERİN YENİDOĞAN VE BEBEKLİK DÖNEMİ NÖROGELİŞİMSEL SONUÇLARA ETKİSİ
Pub Date : 2023-01-12 DOI: 10.38136/jgon.1187862
Ümit Ayşe Tandircioğlu, Ayşe METE YEŞİL, Tolga Çelik, E. Özmert, Süleyman Yi̇ği̇t
AMAÇ: Hipoksik iskemik ensefalopati (HİE); anormal bilinç durumu, nöbetler, çoklu organ yetmezliği ile seyredebilen klinik bir durumdur. Bu retrospektif çalışma ile terapötik hipotermi (TH) uygulanan HİE tanılı yenidoğanların kord kan gazı pH değeri ve kardiyak belirteçleri ile difüzyon Manyetik rezonans görüntüleme (MRG), nörolojik muayeneleri ve gelişimsel sonuçlarının değerlendirilmesi amaçlanmıştır. GEREÇ- YÖNTEM: Ocak 2015- Ocak 2021 tarihleri arasında Hacettepe Üniversitesi İhsan Doğramacı Çocuk Hastanesi Yenidoğan Yoğun Bakım Ünitesi'ne yatırılarak HİE evre 2-3 tanısı ile TH tedavisi almış ve poliklinik izlemine gelen hastalar çalışmaya dahil edildi. Umblikal kord kan gazı pH, Troponin-I, CK-MB değerleri, diffüzyon MRG bulguları ile Bayley Bebekler ve Küçük Çocuklar için Gelişimi Değerlendirme Ölçeği-III (BSID-III) sonuçları karşılaştırıldı. BULGULAR: Çalışmaya alınan 17 hastanın ortalama gebelik haftası 39 hafta (37-41), doğum ağırlıkları ortalama 3360 ± 325 g, 13’ü (%59) erkekti. Hastaların aEEG/EEG izleminde 10 (%59)’unda nöbet tespit edilmedi. Kordon kan gazı pH değeri ortancası ile anormal difüzyon MRG sonuçları arasında istatistiksel olarak fark saptanmadı. BSID-III skorları ile kord kan gazı pH değerinin ortancası arasında; kalp belirteçleri ile difüzyon MRG ve BSID-III sonuçları arasında istatistiksel fark saptanmadı. SONUÇ: Hipoksik iskemik ensefalopati olan bebeklerde TH endikasyonu için kullanılan kord kan gazı değerleri uzun dönem nörolojik-gelişimsel prognozun öngörülmesinde yeterli değildir. Hasta sayısı arttırıldığı takdirde bu hastalarda kalp kasının hipoksiden etkilendiğini gösteren kardiyak enzimleri uzun dönem izlemde bebeğin karşılaşabileceği nörolojik-gelişimsel sorunları öngörmede yararlı olabileceğini söyleyebiliriz.
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引用次数: 0
Erken evre serviks kanseri hastalarında lenf nodunu metastazını predikte eden faktörler 预测早期宫颈癌患者淋巴结转移的因素
Pub Date : 2022-12-14 DOI: 10.38136/jgon.1210845
Burak Ersak, Duygu TUĞRUL ERSAK, Serra Akar, Bülent Özdal, Mahmut Kuntay Kokanalı, S. Serdar, H. Yalçin, İlker Selcuk, Özlem MORALOĞLU TEKİN
Amaç: Serviks kanseri hastalarında lenf nodu metastazının (LNM) değerlendirmesi tedavinin bireyselleştirilmesi için önemli bir konudur. Çalışmamızın amacı, serviks kanserli hastalarda LNM'nin prediktif faktörlerini belirlemektir. Gereç ve Yöntem: Bu retrospektif çalışmaya, 2007'den 2019'a kadar Uluslararası Jinekoloji ve Obstetrik Federasyonu (FIGO) evre IB1-IIA2'nin serviks kanseri hastaları dahil edildi. LNM insidanslarıyla beraber tek ve çok değişkenli modellerde pelvik ve paraaortik LNM için risk faktörlerinin prediktif değeri belirlendi. Bulgular: Çalışmaya dahil edilen 212 hastadan pelvik LNM olan hasta sayısı 81(%38.2), paraaortik LNM'li hasta sayısı 17(%8) idi. Serviks kanseri hastalarında multivariyant analize göre parametriyal tutulum (hazard ratio [HR]: 2.75, 95% confidence interval [CI], 1.18-6.40, p=0.019) ve lenfovasküler tutulum ([HR]: 3.83, 95% [CI], 1.76-8.38, p=0.001) pelvik LNM için bağımsız risk faktörleriydi iken paraaortik LNM için parametriyal tutulum bağımsız risk faktörüydü ([HR]: 3.62, 95% [CI], 1.20-10.98, p=0.023). Sonuç: Serviks kanseri hastalarında pelvik LNM'nin prediktif faktörleri parametrial tutulum ve LVSI iken paraaortik LNM için prediktif risk faktörü parametrial tutulumdu.
目的:评估宫颈癌患者的淋巴结转移(LNM)是个体化治疗的一个重要问题。我们的研究旨在确定宫颈癌患者淋巴结转移的预测因素。材料和方法:这项回顾性研究纳入了 2007 年至 2019 年国际妇产科联盟(FIGO)IB1-IIA2 期宫颈癌患者。研究确定了LNM的发生率以及盆腔和主动脉旁LNM风险因素在单变量和多变量模型中的预测价值。结果在纳入研究的212名患者中,盆腔LNM患者人数为81人(38.2%),主动脉旁LNM患者人数为17人(8%)。多变量分析显示,宫旁受累(危险比 [HR]:2.75,95% 置信区间 [CI],1.18-6.40,P=0.019)和淋巴管受累([HR]:3.83,95% [CI],1.76-8.38,P=0.001)是盆腔LNM的独立危险因素,而宫旁受累是主动脉旁LNM的独立危险因素([HR]:3.62,95% [CI],1.20-10.98,P=0.023)。结论宫颈癌患者盆腔 LNM 的预测因素是宫旁受累和 LVSI,而主动脉旁 LNM 的预测风险因素是宫旁受累。
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引用次数: 0
Evre IIIC Endometrium Kanserinde Paraaortik Lenf Nodu Metastazı Varlığına Göre Klinik, Cerrahi ve Patolojik Faktörlerin Dağılımı
Pub Date : 2022-12-11 DOI: 10.38136/jgon.1186328
Okan Aytekin, Yeşim ÖZKAYA UÇAR, Burak Ersak, Fatih Çelik, Günsu KİMYON CÖMERT, Bülent Özdal
Özet Amaç: Bu çalışmada Evre IIIC1 ve evre IIIC2 endometrium kanserinde, hasta grupları arasında klinik, cerrahi ve patolojik risk faktörlerinin dağılımını incelemek ve farklılığı tanımlamak amaçlanmıştır. Gereçler ve Yöntem: Kliniğimizde FIGO 2009 kriterlerine göre evre IIIC1-2 endometrium kanseri tanısı alan 115 hasta çalışmaya dâhil edildi. Hastaların demografik, klinik, cerrahi ve patolojik özellikleri hasta dosyalarından ve patoloji raporlarından retrospektif olarak elde edildi. Bulgular: Hastaların 39’unda (%33.9) sadece pelvik lenf nodu metastazı, 14’ünde (%12.2) sadece paraaortik lenf nodu metastazı, 62’sinde (%53.9) ise hem pelvik hem paraaortik lenf nodu metastazı mevcuttu. Otuz dokuz (%33.9) hasta FIGO IIIC1, 76 (%66.1) hasta FIGO IIIC2 evredeydi. Evre IIIC2 hasta grubunda evre IIIC1’e göre derin myometrial invazyon ve malign peritoneal sitoloji istatistiksel olarak anlamlı yüksekti. Buna karşın yaş, tümör boyutu, çıkarılan lenf nodu sayısı, preoperatif CA 125 değeri, FIGO grade derecesi, lenfovasküler alan invazyonu, servikal tutulum durumu ve adneksal metastaz durumu ile hastalığın paraaortik bölgeye yayılıp yayılmaması arasında anlamlı farklılık gözlenmedi. Sonuç: Evre IIIC endometrium kanserinde paraaortik lenf nodu metastazı varlığında derin miyometrial invazyon ve malign peritoneal sitoloji görülme olasılığı artmaktadır.
摘要 目的:本研究旨在探讨临床、手术和病理风险因素的分布情况,并确定 IIIC1 期和 IIIC2 期子宫内膜癌患者组间的差异。材料与方法:根据 FIGO 2009 标准,本诊所共纳入 115 例诊断为 IIIC1-2 期子宫内膜癌的患者。研究人员从患者档案和病理报告中回顾性地获取了患者的人口统计学、临床、手术和病理特征。研究结果39例患者(33.9%)仅有盆腔淋巴结转移,14例患者(12.2%)仅有主动脉旁淋巴结转移,62例患者(53.9%)同时有盆腔和主动脉旁淋巴结转移。39例(33.9%)患者为FIGO IIIC1期,76例(66.1%)患者为FIGO IIIC2期。与 IIIC1 期患者相比,IIIC2 期患者的子宫深部肌层浸润和恶性腹腔细胞学在统计学上明显更高。然而,在年龄、肿瘤大小、切除淋巴结数量、术前CA 125值、FIGO分级、淋巴管侵犯、宫颈受累、附件转移情况以及疾病是否扩散至腹主动脉旁区域之间没有观察到明显差异。结论对于 IIIC 期子宫内膜癌,如果存在主动脉旁淋巴结转移,则子宫肌层深部受侵和恶性腹膜细胞学检查的可能性会增加。
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引用次数: 0
Multicenter assessment of mortality risk in the neonatal intensive care unit 新生儿重症监护病房死亡风险的多中心评估
Pub Date : 2022-12-10 DOI: 10.38136/jgon.1166248
Kamuran Suman, E. Gök, P. Bütün, Zafer Bütün, Musa Büyük, M. Suman
OBJECTİVE: In neonatal intensive care, mortality is a source of great pressure and sadness on the family and the doctor. By its nature, intensive care services serve as a support point on the fine line between life and death. Minimizing this mortality is one of our colleagues' primary goals. For this reason, this study, it is aimed to determine the causes that have an effect on mortality and to minimize these causes with subsequent evaluations. MATERİAL AND METHOD: Our study covers the retrospective data of the babies who died in the neonatal unit between 2015 and 2019. In this context, patients who were born at 22 weeks and older and were hospitalized in the neonatal unit or needed resuscitation in the delivery room were included. Our colleagues from three different hospitals participated in this study with the patients they registered. One of these centers is a training and research hospital and the other centers are state hospitals with busy delivery rooms. Babies lost in utero were not included in the study. Maternal and newborn mortality risk factors were recorded in the perinatal period. In addition, family demographic characteristics, causes of death, and mortality rates were recorded. These recorded data were analyzed according to Wiggleswort's mortality classification. Snappe ll scoring was used to evaluate the probability of death. RESULT: Of the 3112 babies admitted to our neonatal units during the aforementioned four years, we lost 79. When we examined the records of the newborns we lost, prematurity stood out as the most common cause of death. The causes we see less frequently, such as fatal congenital anomalies and severe genetic anomalies incompatible with life, drew attention as their incidence decreased. When we focus, we found that the loss rate was higher in the early neonatal period than in other periods. İn further detail, we see that the highest mortality rate occurred on the first day. While losses due to prematurity were more common in the first weeks of gestation, it was observed that the causes of death changed as the weeks of gestation progressed, and the incidence of genetic diseases and congenital anomalies increased. CONCLUSİON: As we know, the causes of neonatal intensive care losses are diverse, although their frequency varies. The most important determinant of this diversity is gestational age. In this retrospective study, we found that causes such as prematurity and congenital anomalies were among the most common causes. Similar to our results, many international publications have shown that these causes have the highest mortality rate. Improving follow-up and care in the perinatal period has an impact on reducing the causes of mortality we listed. Although not all causes can be eliminated, there are ethical debates about abortion for diseases incompatible with life.
OBJECTİVE:在新生儿重症监护中,死亡率给家庭和医生带来了巨大的压力和悲伤。从本质上讲,重症监护服务是生与死之间的一个支撑点。尽量减少这种死亡率是我们同事的主要目标之一。因此,本研究旨在确定影响死亡率的原因,并在随后的评估中尽量减少这些原因。MATERİAL与方法:我们的研究涵盖了2015年至2019年期间在新生儿病房死亡的婴儿的回顾性数据。在这种情况下,22周及以上出生并在新生儿病房住院或需要在产房复苏的患者包括在内。我们来自三家不同医院的同事与他们登记的病人一起参与了这项研究。其中一个中心是培训和研究医院,其他中心是拥有繁忙产房的州立医院。在子宫内丢失的婴儿不包括在这项研究中。在围产期记录产妇和新生儿死亡的危险因素。此外,还记录了家庭人口特征、死亡原因和死亡率。这些记录的数据根据Wiggleswort的死亡率分类进行分析。采用Snappe评分法评价死亡概率。结果:在上述四年中,3112名婴儿入住我们的新生儿病房,我们失去了79名。当我们检查我们失去的新生儿的记录时,早产是最常见的死亡原因。我们很少看到的原因,如致命的先天性异常和与生命不相容的严重遗传异常,随着发病率的下降而引起人们的注意。当我们集中注意力时,我们发现新生儿早期的损失率高于其他时期。İn更详细地说,我们看到第一天的死亡率最高。虽然早产造成的死亡在妊娠最初几周更为常见,但据观察,随着妊娠几周的进展,死亡原因发生变化,遗传疾病和先天性异常的发生率增加。CONCLUSİON:正如我们所知,新生儿重症监护损失的原因多种多样,尽管其频率各不相同。这种多样性最重要的决定因素是胎龄。在这项回顾性研究中,我们发现早产和先天性异常等原因是最常见的原因。与我们的研究结果类似,许多国际出版物表明,这些原因的死亡率最高。改善围产期的随访和护理对减少我们列出的死亡原因有影响。虽然并非所有的原因都可以消除,但对于因与生命不相容的疾病而堕胎的问题,存在着伦理上的争论。
{"title":"Multicenter assessment of mortality risk in the neonatal intensive care unit","authors":"Kamuran Suman, E. Gök, P. Bütün, Zafer Bütün, Musa Büyük, M. Suman","doi":"10.38136/jgon.1166248","DOIUrl":"https://doi.org/10.38136/jgon.1166248","url":null,"abstract":"OBJECTİVE: In neonatal intensive care, mortality is a source of great pressure and sadness on the family and the doctor. By its nature, intensive care services serve as a support point on the fine line between life and death. Minimizing this mortality is one of our colleagues' primary goals. For this reason, this study, it is aimed to determine the causes that have an effect on mortality and to minimize these causes with subsequent evaluations. \u0000MATERİAL AND METHOD: \u0000Our study covers the retrospective data of the babies who died in the neonatal unit between 2015 and 2019. In this context, patients who were born at 22 weeks and older and were hospitalized in the neonatal unit or needed resuscitation in the delivery room were included. Our colleagues from three different hospitals participated in this study with the patients they registered. One of these centers is a training and research hospital and the other centers are state hospitals with busy delivery rooms. Babies lost in utero were not included in the study. Maternal and newborn mortality risk factors were recorded in the perinatal period. In addition, family demographic characteristics, causes of death, and mortality rates were recorded. These recorded data were analyzed according to Wiggleswort's mortality classification. Snappe ll scoring was used to evaluate the probability of death. \u0000RESULT: Of the 3112 babies admitted to our neonatal units during the aforementioned four years, we lost 79. When we examined the records of the newborns we lost, prematurity stood out as the most common cause of death. The causes we see less frequently, such as fatal congenital anomalies and severe genetic anomalies incompatible with life, drew attention as their incidence decreased. When we focus, we found that the loss rate was higher in the early neonatal period than in other periods. İn further detail, we see that the highest mortality rate occurred on the first day. While losses due to prematurity were more common in the first weeks of gestation, it was observed that the causes of death changed as the weeks of gestation progressed, and the incidence of genetic diseases and congenital anomalies increased. \u0000 \u0000CONCLUSİON: As we know, the causes of neonatal intensive care losses are diverse, although their frequency varies. The most important determinant of this diversity is gestational age. In this retrospective study, we found that causes such as prematurity and congenital anomalies were among the most common causes. Similar to our results, many international publications have shown that these causes have the highest mortality rate. \u0000Improving follow-up and care in the perinatal period has an impact on reducing the causes of mortality we listed. Although not all causes can be eliminated, there are ethical debates about abortion for diseases incompatible with life.","PeriodicalId":119624,"journal":{"name":"Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129734707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of Fetal Thymus Size in Small for Gestational Age and Growth Restricted Fetuses 小胎龄和生长受限胎胸腺大小的评估
Pub Date : 2022-12-04 DOI: 10.38136/jgon.1204415
Selcan Sınacı, D. Şahın
Objective: The purpose of this study was to analyze the fetal thymus size by sonography in healthy, small for gestational age (SGA), and fetal growth restriction (FGR) pregnancies and investigate if there is a difference between healthy fetuses and those with growth restriction. Study Design: The thymic-thoracic ratio (TTR), transverse diameter, and perimeter of the fetal thymus were prospectively measured in SGA and FGR pregnancies between the gestational ages of 20 and 37 weeks and compared with healthy controls. Fetal abdominal circumference (AC) or estimated fetal weight (EFW)
目的:本研究的目的是通过超声分析健康、小胎龄(SGA)和胎儿生长受限(FGR)妊娠的胎儿胸腺大小,探讨健康胎儿和生长受限胎儿胸腺大小的差异。研究设计:在孕周20 ~ 37周的SGA和FGR孕妇中,前瞻性地测量胸腺胸廓比(TTR)、胸腺横向直径和胸腺周长,并与健康对照组进行比较。胎儿腹围(AC)或估计胎儿体重(EFW)
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引用次数: 0
The Assessment of The Level of Covid-19 Fear And State-Trait Anxiety of The Healthcare Workers: The Sample Of Turkey 医护人员对Covid-19恐惧水平和状态-特质焦虑水平的评估:以土耳其为例
Pub Date : 2022-11-19 DOI: 10.38136/jgon.1062140
Nükhet Kaçar, F. Sayıner, Özlem Moraloğlu Tekin
ABSTRACT Aim: In our study, it was aimed to analyze the relationship between the level of covid fear and state-trait anxiety of the healthcare professionals. Materials and Methods: 203 healthcare workers working in healthcare organizations during pandemia participated in our descriptive study made in May 2021. The used data collection tools are descriptive features form, Covid-19 Fear Scale (CFS) and State-Trait Anxiety (STAI) scale. The data were collected by using social media because the pandemia existed. Results: In our study, it was found that the CFS points (.005) of healthcare workers who did not use accommodation services arranged by the TR Ministry of Health, are more statistically significant than the others. The STAI points (.008) of healthcare workers who did not get any psychological support are less than the ones who got support, the points of STAI (.000) of healthcare workers who did not think about quitting their jobs were less than the others. The healthcare workers who did not think about having psychological support, have fewer points of CFS (.002) and STAI (.001) than the ones who think to get support. In addition between the points of CFS and STAI has a statistically significant relationship (.000). Conclusion: Increasing the number of healthcare workers, strengthening their motivation, providing annual leave, giving education about covid, providing psychological support are helpful to decrease the effects of pandemia on healthcare workers.
摘要目的:本研究旨在分析医护人员新冠病毒恐惧水平与状态-特质焦虑的关系。材料与方法:203名在大流行期间在卫生保健机构工作的卫生保健工作者参与了我们于2021年5月进行的描述性研究。使用的数据收集工具是描述性特征表、Covid-19恐惧量表(CFS)和状态-特质焦虑量表(STAI)。这些数据是通过社交媒体收集的,因为大流行已经存在。结果:在我们的研究中,没有使用TR卫生部安排的住宿服务的医护人员的CFS分(.005)比其他医护人员更具统计学意义。未获得任何心理支持的医务人员的sti(.008)分低于获得支持的医务人员,未考虑过辞职的医务人员的sti(.000)分低于其他医务人员。未考虑获得心理支持的医护人员的CFS(.002)分和STAI(.001)分低于考虑获得支持的医护人员。此外,CFS与STAI之间有统计学意义的关系(0.000)。结论:增加医护人员数量、增强医护人员积极性、提供年假、开展疫情教育、提供心理支持等措施有助于降低疫情对医护人员的影响。
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引用次数: 0
Plasenta Previa Tanılı Hastalarda Peripartum Histerektominin Depresyon Düzeylerine Etkisi
Pub Date : 2022-11-19 DOI: 10.38136/jgon.1063444
Merve ALDIKAÇTIOĞLU TALMAÇ, Özge Özdemi̇r, Aslı ENEZ DARÇIN, Ibrahim Polat, Cemal Ark
Amaç: Bu çalışmada plasenta previa tanılı hastaların, operasyonlarından sonraki dönemde depresif belirti şiddetleri araştırıldı ve uterusu kaybetmenin sonucunda duygu durumlarındaki değişim incelendi. Gereçler ve Yöntem: Çalışmaya Mart 2012-Kasım 2014 tarihleri arasında plasenta previa nedeniyle sezaryen histerektomi yapılan toplam 59 hasta ile aynı tanı nedeniyle sezaryen olan ancak histerektomi yapılmayan toplam 60 hasta alındı. Hastalarda depresyon varlığı araştırıldı ve Beck Depresyon Ölçeği (BDÖ) ile depresif belirti şiddeti değerlendirildi. Bulgular: Peripartum histerektomi yapılan hasta grubunda ortalama BDÖ puanı 11±6, histerektomi yapılmayan grupta ise 4±2 bulundu. Histerektomi yapılan grupta ortalama BDÖ puanları istatistiksel olarak anlamlı bulundu (p
研究目的本研究调查了前置胎盘患者术后抑郁症状的严重程度,并分析了患者因失去子宫而产生的情绪变化。材料和方法:本研究共纳入了 59 名在 2012 年 3 月至 2014 年 11 月期间因前置胎盘而接受剖腹产子宫切除术的患者,以及 60 名因相同诊断而接受剖腹产手术但未切除子宫的患者。研究人员调查了患者是否患有抑郁症,并使用贝克抑郁量表(BDS)评估了抑郁症状的严重程度。结果显示围产期子宫切除组的平均 BDI 分数为 11±6,非子宫切除组为 4±2。子宫切除组的平均 BDI 评分具有统计学意义(p
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引用次数: 0
RETROSPECTIVE STUDY FOR PREDICTING PERINATAL OUTCOME USING CEREBROPLACENTAL RATIO IN FETAL GROWTH RESTRICTED PREGNANCY 利用脑胎盘比预测胎儿生长受限妊娠围产儿结局的回顾性研究
Pub Date : 2022-11-19 DOI: 10.38136/jgon.1065316
Hatice LAÇİN TUĞAN, S. Özden, Koray Gök
ABSTRACT Objective: To investigate and predict perinatal outcomes of pregnancies affected with fetal growth restriction by cerebroplacental ratio. Material and Methods: A retrospective study was conducted based on 100 high-risk pregnant who referred to the antenatal clinic. 66 pregnant women were diagnosed with ıntrauterine growth restriction. And 34 pregnant women were diagnosed with small for gestational age. Baseline demographic, past obstetric and medical histories were recorded for all patients. Intrauterine growth retardation was defined as an estimated weight below the 10th percentile for gestational age based on sonographic measurement.‘ small for gestational age’ diagnosis shows that fetal weight or fetal abdomainal circunference measurement is below 10th percentile; but it was diagnosed in fetuses with normal doppler parameters and no pathological factors were preventing the fetus from reaching its expected growth potential. Doppler ultrasound of middle cerebral arteries and umbilical arteries were used to assess pregnancies. Cerebroplacental rate (CPR); It is calculated by dividing MCA percentile index to UA percentile index. The cerebroplacental doppler ratio less than 1 was accepted abnormal. Adverse perinatal outcomes for newborns were documented for all cases. Results: 100 pregnant women were classified into two groups according to cerebroplacental ratio. Cerebroplacental ratio ratio of Group A is greater than 1 (n=87). And cerebroplacental ratio ratio of Group B is less than 1 (n=13). Perinatal morbidity statistically significantly increased in Group B. The fetuses with abnormal cerebroplacental ratıo were strongly correlated with worse fetal prognosis. Respiratory distress syndrome rates (p = 0.043; p
目的:探讨脑胎盘比对胎儿生长受限妊娠围产儿结局的影响。材料与方法:对100例到产前门诊就诊的高危孕妇进行回顾性研究。66名孕妇被诊断为ıntrauterine生长受限。34名孕妇被诊断为小于胎龄。记录了所有患者的基线人口统计、过去的产科和病史。宫内生长迟缓定义为基于超声测量的估计体重低于胎龄的第10个百分位数。“小于胎龄”诊断表明胎儿体重或胎儿腹围测量值低于10个百分位数;但在多普勒参数正常的胎儿中诊断出来,没有病理因素阻止胎儿达到预期的生长潜力。采用多普勒超声检查大脑中动脉和脐动脉,评估妊娠情况。脑胎盘率(CPR);用MCA百分位数指数除以UA百分位数指数计算。脑胎盘多普勒比值小于1为异常。所有病例均记录了新生儿的不良围产期结局。结果:100例孕妇按脑胎盘比分为两组。A组脑胎盘比大于1 (n=87)。B组脑胎盘比小于1 (n=13)。b组围产期发病率显著增高,脑胎盘异常ratıo与胎儿预后差密切相关。呼吸窘迫综合征发生率(p = 0.043;p
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引用次数: 0
Is SARS-CoV-2 a risk factor for hypotension during spinal anesthesia for obstetric patients? SARS-CoV-2是产科患者脊柱麻醉期间低血压的危险因素吗?
Pub Date : 2022-10-30 DOI: 10.38136/jgon.1135792
A. Güler, N. Özcan
Background: Since the onset of COVID-19, recommendations suggest the use of neuraxial anesthesia, over general anesthesia for cesarian section to avoid the risks of aerosolization associated with intubation and extubation. But the safety of performing spinal anesthesia is unclear especially for post spinal hypotension, during the presence of active COVID-19. According to a few studies there was a controversial discussion about the safety of regional anesthesia. In this study we aimed to compare the incidence of hypotension in COVID-19 pregnant patients between non-COVID 19 pregnant patients in the literature to see if the spinal anesthesia is safe or if it poses an additional risk. Materials and Methods: Medical records of COVID-19 pregnant women for cesarean section from the beginning of the pandemic up to December 2020 were retrospectively retrieved. All the demographic-vital data, including systolic and diastolic blood pressure (SBP-DBP), ephedrine-atropine doses, infusion volumes, and nausea and vomiting were retrospectively analyzed. Results: Spinal anesthesia induced hypotension was seen 54 of the patients (21,69%). And vasopressors (Ephedrine) were used to all hypotensive patients. Demographic data’s, the amount of bupivacaine and crystalloid volume which used before the spinal anesthesia showed no differences between hypotensive and non-hypotensive patients. Conclusion: This is the first retrospective study which shows 249 COVID 19 patients’ data in one center that no significant difference was seen in the incidence of hypotension associated with spinal anesthesia for COVID-19 cesarean section compared to non-COVID group in literature. We recommend using of regional anesthesia safely for patients and anesthesiologists during active COVID-19 patients.
背景:自COVID-19发病以来,建议在剖宫产术中使用神经轴麻醉,而不是全身麻醉,以避免与插管和拔管相关的雾化风险。但实施脊髓麻醉的安全性尚不清楚,特别是在存在活动性COVID-19的脊髓低血压后。根据一些研究,关于区域麻醉的安全性存在争议。在本研究中,我们旨在比较文献中COVID-19妊娠患者与非COVID-19妊娠患者的低血压发生率,以了解脊髓麻醉是否安全或是否会带来额外风险。材料与方法:回顾性检索自疫情开始至2020年12月的COVID-19孕妇剖宫产病历。回顾性分析所有人口统计学数据,包括收缩压和舒张压(SBP-DBP)、麻黄碱-阿托品剂量、输注量、恶心和呕吐。结果:腰麻致低血压54例(21.69%)。所有低血压患者均应用血管加压药(麻黄碱)。低血压和非低血压患者在脊髓麻醉前布比卡因用量和晶体体积方面无统计学差异。结论:这是文献中首次对249例COVID-19患者资料进行回顾性研究,发现COVID-19剖宫产术后腰麻相关低血压发生率与非COVID-19组无显著差异。我们建议患者和麻醉师在COVID-19活动性患者期间安全地使用区域麻醉。
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引用次数: 0
Do the Number of Oocytes Retrieved and Mature Oocyte Rate in the Cohort Affect IVF Results? 队列中取卵数量和成熟卵母细胞率是否影响IVF结果?
Pub Date : 2022-10-24 DOI: 10.38136/jgon.1176830
Mehmet Caner Özer, Ayten Türkkani, Derya ÖZDEMİR TAŞ, Ş. Özyer, Mustafa Turan, Nafiye Yilmaz, Özlem Moraloğlu Tekin
Aim: The aim of this study was to investigate the effects of the number of oocytes retrieved and rate of mature oocytes on IVF outcomes in single fresh embryo transfer. Materials and Medhods: Two main groups were formed regarding number of oocytes retrieved and mature oocyte rate. According to the number of oocytes retrieved in 561 IVF cycles, 0-5 (n=175) oocytes were determined as group 1, 6-10 (n=214) oocytes as group 2, 11-15 (n=121) oocytes as group 3 and 16 or more oocytes as group 4 (n=51). Regarding mature oocyte (metaphase II, MII oocyte) rate, three groups were formed: group 1A (n=338) 76-100% mature oocytes, group 2A (n=150) 75-50% mature oocytes, and group 3A (n=73) less than 50% mature oocytes. Results: The number of oocytes retrieved was negatively correlated fertilization rate, whereas Β-hCG positivity and clinical pregnancy rates were observed to be better in the 6-10 oocytes group. The mean age, basal LH, and ovulation trigger day E2 levels, and fertilization rate were differed significantly between three groups of mature oocyte rate. Conclusion: In conclusion, MII oocyte rates in the cohort, regardless of the number of oocytes retrieved, did not affect IVF outcomes.
目的:探讨单新鲜胚胎移植中卵母细胞数量和成熟卵母细胞率对体外受精结果的影响。材料与方法:取卵数量和成熟卵母细胞率分为两组。根据561个IVF周期取卵数,0-5个(n=175)个卵为第1组,6-10个(n=214)个卵为第2组,11-15个(n=121)个卵为第3组,16个及以上卵为第4组(n=51)。成熟卵母细胞(中期II, MII卵母细胞)率分为三组:1A组(n=338)成熟卵母细胞76-100%,2A组(n=150)成熟卵母细胞75-50%,3A组(n=73)成熟卵母细胞不足50%。结果:取卵数与受精率呈负相关,6-10个卵母细胞组Β-hCG阳性及临床妊娠率较好。平均年龄、基础黄体生成素、促排卵日E2水平和受精率在三组成熟卵母细胞率之间差异显著。结论:总之,队列中的MII卵母细胞率,无论提取的卵母细胞数量如何,都不会影响IVF结果。
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引用次数: 0
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Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi
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