E. Çölgeçen, H. Yıldız, Kemal Özyurt, Caner Ozbey, Hanife Icigen, Ragıp Ertaş
Eruptive xanthomas are characterized by large numbers of yellow papules, typically 1-4 m in size, sometimes with an erythematous halo, sometimes pruritic, of sudden onset and generally observed on the extensor surfaces of the extremities. These are seen in less than 0.1% of diabetic patients. Diabetes mellitus is the most common secondary cause of type 5 hyperlipoproteinemia, a form of chylomcronemia. Eruptive xanthomas generally emerge at triglyceride levels above 2000 mg/dL proceeding with chylomicronemia. This case report of a 36-year-old woman diagnosed with eruptive xanthoma on the basis of clinical and histopathological findings is presented in order to emphasize that these are an important finding of diseases associated with metabolic syndrome, such as diabetes mellitus and hypertriglyceridemia.
{"title":"Eruptive Xanthomas in a Patient with MetabolicSyndrome","authors":"E. Çölgeçen, H. Yıldız, Kemal Özyurt, Caner Ozbey, Hanife Icigen, Ragıp Ertaş","doi":"10.29333/ejgm/81912","DOIUrl":"https://doi.org/10.29333/ejgm/81912","url":null,"abstract":"Eruptive xanthomas are characterized by large numbers of yellow papules, typically 1-4 m in size, sometimes with an erythematous halo, sometimes pruritic, of sudden\u0000onset and generally observed on the extensor surfaces of the extremities. These are seen in less than 0.1% of diabetic patients. Diabetes mellitus is the most common\u0000secondary cause of type 5 hyperlipoproteinemia, a form of chylomcronemia. Eruptive xanthomas generally emerge at triglyceride levels above 2000 mg/dL proceeding\u0000with chylomicronemia. This case report of a 36-year-old woman diagnosed with eruptive xanthoma on the basis of clinical and histopathological findings is presented in\u0000order to emphasize that these are an important finding of diseases associated with metabolic syndrome, such as diabetes mellitus and hypertriglyceridemia.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77271232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Korkmaz, Ömer Özer, Şüheda Kaya, A. Kazğan, M. Atmaca
Objective:It is considered that, in addition to different effects of colors on mood, psychopathological processes are also a conductive factor in color preferences. Thus, the objective of the present study was to investigate whether there was a relationship between color preferences and impulsive behavior.Method:Socio-demographic information, anxiety levels, depression and impulsivity levels of 200 individuals aged 18-50, which were selected randomly, were assessed. Beck Anxiety (BAI), Beck Depression(BDI) and Barrat Impulsivity Scales(BIS) were applied to all participants. They were asked the first color that comes to mind and their favorite colors. Preferred colors were divided into three groups of cold (blue, purple, green), warm (red, yellow, pink, brown) and neutral colors (black, white, grey).Results:Study group included 87 males (43.5%), 113 females (56.5%) and their mean age was 26.9±6.2 years. (female mean age: 25.9±5.5; male mean age: 28.1±6.9). The first color that came to mind was blue (32%), followed by red (20%). Their most favorite colors were blue (33%) and black (20%). BIS total points were the highest for those who chose yellow, blue, purple and black colors, respectively. BAI was the highest in participants who preferred color black and BDI was the highest in participants who preferred color grey. Those who scored the highest points in BAI and BDI preferred neutral colors. Anxiety scores for those preferring cold, warm and neutral colors were statistically significantly different (p=0.02).Conclusion:Color preferences are closely related to impulsivity. Furthermore, anxiety and depression levels of individuals also affect their color preferences.
{"title":"The correlation between color choices and impulsivity,anxiety and depression","authors":"S. Korkmaz, Ömer Özer, Şüheda Kaya, A. Kazğan, M. Atmaca","doi":"10.29333/EJGM/81905","DOIUrl":"https://doi.org/10.29333/EJGM/81905","url":null,"abstract":"Objective:It is considered that, in addition to different effects of colors on mood, psychopathological processes are also a conductive factor in color preferences. Thus,\u0000the objective of the present study was to investigate whether there was a relationship between color preferences and impulsive behavior.Method:Socio-demographic information, anxiety levels, depression and impulsivity levels of 200 individuals aged 18-50, which were selected randomly, were assessed.\u0000Beck Anxiety (BAI), Beck Depression(BDI) and Barrat Impulsivity Scales(BIS) were applied to all participants. They were asked the first color that comes to mind and their\u0000favorite colors. Preferred colors were divided into three groups of cold (blue, purple, green), warm (red, yellow, pink, brown) and neutral colors (black, white, grey).Results:Study group included 87 males (43.5%), 113 females (56.5%) and their mean age was 26.9±6.2 years. (female mean age: 25.9±5.5; male mean age: 28.1±6.9).\u0000The first color that came to mind was blue (32%), followed by red (20%). Their most favorite colors were blue (33%) and black (20%). BIS total points were the highest for\u0000those who chose yellow, blue, purple and black colors, respectively. BAI was the highest in participants who preferred color black and BDI was the highest in participants\u0000who preferred color grey. Those who scored the highest points in BAI and BDI preferred neutral colors. Anxiety scores for those preferring cold, warm and neutral colors\u0000were statistically significantly different (p=0.02).Conclusion:Color preferences are closely related to impulsivity. Furthermore, anxiety and depression levels of individuals also affect their color preferences.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88057723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. El-Agroudy, S. A. Arrayed, Sumaya AlGhareeb, E. Farid, H. Alhelow, Sadiq Abdulla
Background:We report a prospective, open-label, randomized study to evaluate the safety and efcacy of converting patients with stable renal function from Tacrolimus (Tac)-based regimen to a Sirolimus (SRL)-based regimen after kidney transplantation.Methods:Fifty eight low risk renal allograft recipients who were eligible to the study, 6 months posttransplant and receiving Tac, were randomly assigned to continue Tac (n=29) or convert to SRL (n=29). We evaluated the 3-year outcomes including patient and graft survival, graft function and safety profle.Results:3-year patient and graft survival in SRL and Tac groups was 93.1% vs. 100% (P=0.04), and 89.7% vs. 100% (P=0.04), respectively. However, the SRL group had signifcantly better renal function, from the second year post-transplant until the last follow-up. Four (13.8%) patients in the SRL group and 3 (10.3%) in the Tac group (P=0.5) developed biopsy proven acute rejection. Mean urinary protein excretion increased signifcantly after SRL conversion. Diastolic blood pressure was signifcantly lower in patients who eliminated tacrolimus (80.4 vs. 75.6 mmHg) (P = 0.03). Mean hemoglobin concentrations decreased after SRL conversion and remained signifcantly lower from 12 months to 36 months (P=0.01). The mean serum cholesterol and triglyceride levels increased signifcantly in the SRL group, (P < 0.05).Conclusions:our experience demonstrates that conversion to sirolimus from calcineurin inhibitors (CNI)-based therapy may result in better renal function and blood pressure control in renal transplant recipients without an increased risk of acute rejection. However, these benefts have not resulted in a growing advantage in graft or patient survival.
{"title":"Sirolimus-based, calcineurin inhibitor- free regimen in kidney transplant patients: An open-label, randomized, controlled trial","authors":"A. El-Agroudy, S. A. Arrayed, Sumaya AlGhareeb, E. Farid, H. Alhelow, Sadiq Abdulla","doi":"10.29333/EJGM/81898","DOIUrl":"https://doi.org/10.29333/EJGM/81898","url":null,"abstract":"Background:We report a prospective, open-label, randomized study to evaluate the safety and efcacy of converting patients with stable renal function from Tacrolimus (Tac)-based regimen to a Sirolimus (SRL)-based regimen after kidney transplantation.Methods:Fifty eight low risk renal allograft recipients who were eligible to the study, 6 months posttransplant and receiving Tac, were randomly assigned to continue Tac (n=29) or convert to SRL (n=29). We evaluated the 3-year outcomes including patient and graft survival, graft function and safety profle.Results:3-year patient and graft survival in SRL and Tac groups was 93.1% vs. 100% (P=0.04), and 89.7% vs. 100% (P=0.04), respectively. However, the SRL group had signifcantly better renal function, from the second year post-transplant until the last follow-up. Four (13.8%) patients in the SRL group and 3 (10.3%) in the Tac group (P=0.5) developed biopsy proven acute rejection. Mean urinary protein excretion increased signifcantly after SRL conversion. Diastolic blood pressure was signifcantly lower in patients who eliminated tacrolimus (80.4 vs. 75.6 mmHg) (P = 0.03). Mean hemoglobin concentrations decreased after SRL conversion and remained signifcantly lower from 12 months to 36 months (P=0.01). The mean serum cholesterol and triglyceride levels increased signifcantly in the SRL group, (P < 0.05).Conclusions:our experience demonstrates that conversion to sirolimus from calcineurin inhibitors (CNI)-based therapy may result in better renal function and blood pressure control in renal transplant recipients without an increased risk of acute rejection. However, these benefts have not resulted in a growing advantage in graft or patient survival.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82507170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adenoid cystic carcinoma are relatively less common type of salivary gland tumour including parotid gland, and is the only histological type having propensity to spread distantly by lympho-hematogenous and other ‘classical perineural’ spread. Adenoid cystic carcinoma as a primary salivary gland tumor arising in bronchus is known entity although is exceptionally rare. In this case report, 43 year male with past history of adenoid cystic carcinoma of left parotid gland which was operated 4 years back and received post-operative radiotherapy presented with shortness of breath clinically. We observed ‘cannon ball opacities bilaterally’ over chest radiograph and Endobronchial growth during bronchoscopy. Histopathology confirmed as a metastatic lung cancer. We recommend bronchoscopy of all the cases with bilateral cannon ball metastasis as it will help in diagnosis endobronchial growth.
{"title":"A rare presentation of Adenoid cystic carcinoma ofparotid gland as metastatic Endobronchial growthduring Bronchoscopy with multiple ‘Bilateral Cannonball’ lung metastasis in chest radiograph","authors":"Patil Shital, L. Kasture","doi":"10.29333/EJGM/81911","DOIUrl":"https://doi.org/10.29333/EJGM/81911","url":null,"abstract":"Adenoid cystic carcinoma are relatively less common type of salivary gland tumour including parotid gland, and is the only histological type having propensity to\u0000spread distantly by lympho-hematogenous and other ‘classical perineural’ spread. Adenoid cystic carcinoma as a primary salivary gland tumor arising in bronchus\u0000is known entity although is exceptionally rare. In this case report, 43 year male with past history of adenoid cystic carcinoma of left parotid gland which was\u0000operated 4 years back and received post-operative radiotherapy presented with shortness of breath clinically. We observed ‘cannon ball opacities bilaterally’ over\u0000chest radiograph and Endobronchial growth during bronchoscopy. Histopathology confirmed as a metastatic lung cancer. We recommend bronchoscopy of all the cases\u0000with bilateral cannon ball metastasis as it will help in diagnosis endobronchial growth.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79554536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background:Obstructive sleep apnea syndrome (OSAS) is a disorder characterized by repetitive episodes of complete or partial airway obstruction due to pharyngeal collapse during sleep. The pathogenesis of OSAS is still not clear, although studies showing that OSAS is caused mainly by upper respiratory tract stenosis mainly at nasopharynx. The purpose of this study is to show the paranasal sinus (PNS) pathologies and nasal cavity volume, nasopharynx volume and adenoid diameters of OSAS patients, and correlate the multi detector computed tomography (MDCT) findings with severity of the disease.Methods:A total of 48 (34 male and 14 female) OSAS patients were evaluated retrospectively between November 2011 and July 2012. Polysomnography and MDCT was performed to all patients.Results:Mean age of the patients were 45.46±8.82 years. The body mass index grades were normal weight in 5 (10.4%), overweight in 13 (27.1%), obese in 30 (62.5%) patients. The OSAS were graded as mild (5 patients, 10.4%), moderate (16 patients, 33.3%) and severe (27 patients, 56.3%) according to their polysomnography findings. The correlation between OSAS grades and radiological measurements were low. There was no difference between gender regardless from the OSAS grades (p≥0.05).Conclusion:OSAS patients have nasal septal spur formation and septal deviation which may aggravate their syndrome. PNS MDCT is important to demonstrate these disorders. Further studies comparing patients and controls may show 3D volumetric changes of the PNS region.
{"title":"Paranasal Sinus Computed Tomography VolumetricFindings of Obstructive Sleep Apnea Syndrome","authors":"G. Orman, N. Huseyinoglu, M. Duymuş","doi":"10.29333/EJGM/81902","DOIUrl":"https://doi.org/10.29333/EJGM/81902","url":null,"abstract":"Background:Obstructive sleep apnea syndrome (OSAS) is a disorder characterized by repetitive episodes of complete or partial airway obstruction due to pharyngeal\u0000collapse during sleep. The pathogenesis of OSAS is still not clear, although studies showing that OSAS is caused mainly by upper respiratory tract stenosis mainly at\u0000nasopharynx. The purpose of this study is to show the paranasal sinus (PNS) pathologies and nasal cavity volume, nasopharynx volume and adenoid diameters of OSAS\u0000patients, and correlate the multi detector computed tomography (MDCT) findings with severity of the disease.Methods:A total of 48 (34 male and 14 female) OSAS patients were evaluated retrospectively between November 2011 and July 2012. Polysomnography and MDCT was\u0000performed to all patients.Results:Mean age of the patients were 45.46±8.82 years. The body mass index grades were normal weight in 5 (10.4%), overweight in 13 (27.1%), obese in 30 (62.5%)\u0000patients. The OSAS were graded as mild (5 patients, 10.4%), moderate (16 patients, 33.3%) and severe (27 patients, 56.3%) according to their polysomnography findings.\u0000The correlation between OSAS grades and radiological measurements were low. There was no difference between gender regardless from the OSAS grades (p≥0.05).Conclusion:OSAS patients have nasal septal spur formation and septal deviation which may aggravate their syndrome. PNS MDCT is important to demonstrate these\u0000disorders. Further studies comparing patients and controls may show 3D volumetric changes of the PNS region.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89864553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background:Fibularis tertius (FT) is a variant muscle of the anterior compartment of leg which involves in dorsiflexion and evertion of the foot. Literature shows that the reported prevalence of FT ranges from 49-100%. This study investigates the prevalence of FT in South-eastern population of India using surface anatomy techniques in living subjects and comparing it with the studies available in the literature.Material and Methods:Study included the evaluation of 195 subjects from Year 1 & 2 medical students (102 females and 93 males) which correspond to 390 feet in total. The average age of the sample was 17.9 years, with lower and upper limits of 17 and 20 years, respectively. The presence of FT was identified with a standard palpation technique that determines the presence of muscle on the basis of the progression tests called F1, F2, and F3.Results:The total FT prevalence was found to be 52% of the sample. On the right foot, FT was found to be 26.6% in males and 24.6% in females and on the left foot, it was 27.2% in males and 25.6% in females. FT palpation criterion showed 0 (zero) cases for F1, 31 cases for F2 and 172 cases for F3.Conclusions:This surface anatomical study reports for the first time the FT prevalence in South-eastren population of India. Further studies on prevalence of FT are needed to understand its role in biomechanics and reconstructive surgeries of the ankle and foot.
{"title":"Prevalence of Fibularis Tertius Muscle in Southeastren Indian Population: a Surface Anatomical Study","authors":"B. K. Potu, Vinod Kumar, A. Salem, M. Abu-Hijleh","doi":"10.29333/EJGM/81900","DOIUrl":"https://doi.org/10.29333/EJGM/81900","url":null,"abstract":"Background:Fibularis tertius (FT) is a variant muscle of the anterior compartment of leg which involves in dorsiflexion and evertion of the foot. Literature shows that the reported prevalence of FT ranges from 49-100%. This study investigates the prevalence of FT in South-eastern population of India using surface anatomy techniques in living subjects and comparing it with the studies available in the literature.Material and Methods:Study included the evaluation of 195 subjects from Year 1 & 2 medical students (102 females and 93 males) which correspond to 390 feet in total. The average age of the sample was 17.9 years, with lower and upper limits of 17 and 20 years, respectively. The presence of FT was identified with a standard palpation technique that determines the presence of muscle on the basis of the progression tests called F1, F2, and F3.Results:The total FT prevalence was found to be 52% of the sample. On the right foot, FT was found to be 26.6% in males and 24.6% in females and on the left foot, it was 27.2% in males and 25.6% in females. FT palpation criterion showed 0 (zero) cases for F1, 31 cases for F2 and 172 cases for F3.Conclusions:This surface anatomical study reports for the first time the FT prevalence in South-eastren population of India. Further studies on prevalence of FT are needed to understand its role in biomechanics and reconstructive surgeries of the ankle and foot.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90235284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kidney dysfunction is a common and potentially life-threating event in patients with cirrhosis, and underlying mechanisms for renal dysfunction are quite variable. Acute kidney injury (AKI) is relatively frequent encountered in approximately 20% of hospitalized patients with cirrhosis. Nevertheless, chronic kidney disease (CKD) occurs in almost 1% of all patients with cirrhosis. In this review various renal problems encountered in cirrhotic patients are discussed and strategies to prevent renal dysfunction are suggested.
{"title":"Renal dysfunctions in cirrhosis","authors":"M. Bıyık, Mehmet Asıl, Z. Biyik","doi":"10.29333/EJGM/81907","DOIUrl":"https://doi.org/10.29333/EJGM/81907","url":null,"abstract":"Kidney dysfunction is a common and potentially life-threating event in patients with cirrhosis, and underlying mechanisms for renal dysfunction are quite variable.\u0000Acute kidney injury (AKI) is relatively frequent encountered in approximately 20% of hospitalized patients with cirrhosis. Nevertheless, chronic kidney disease (CKD)\u0000occurs in almost 1% of all patients with cirrhosis. In this review various renal problems encountered in cirrhotic patients are discussed and strategies to prevent renal\u0000dysfunction are suggested.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74779118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Kokten, F. M. Hanege, O. Çam, L. Uzun, M. Tekin
Peripheric facial paralysis may be observed primary or secondary causes. Firearm injuries may cause facial paralysis via direct injury or ballistic effects. Ballistic effects may be observed far beyond the bullet trace. In this article we present an unusual late peripheric facial paralysis onset related with ballistic effect a firearm injury to the left maxillary sinus. Due to late onset of facial paralysis after firearm injury; differential diagnosis and ballistic effects have been discussed.
{"title":"An unusual peripheric facial paralysis onset","authors":"N. Kokten, F. M. Hanege, O. Çam, L. Uzun, M. Tekin","doi":"10.29333/EJGM/81910","DOIUrl":"https://doi.org/10.29333/EJGM/81910","url":null,"abstract":"Peripheric facial paralysis may be observed primary or secondary causes. Firearm injuries may cause facial paralysis via direct injury or ballistic effects. Ballistic effects\u0000may be observed far beyond the bullet trace. In this article we present an unusual late peripheric facial paralysis onset related with ballistic effect a firearm injury to\u0000the left maxillary sinus. Due to late onset of facial paralysis after firearm injury; differential diagnosis and ballistic effects have been discussed.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79291966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This case report is to enlighten the awareness on spinal epidural haematoma due to warfarin. A 58-year-old man who had been on prophylactic anticoagulant therapy after aortic valve replacement since 1998, had presented with acute onset of reduced sensation and weakness in both lower extremities 3 days prior to the admission to our centre. His prothrombin time (PT) was 46.8 seconds, international normalized ratio (INR) was 5.11, and activated partial thromboplastin time (APTT) was 167.6 seconds (control, 31.3-46.1 seconds). Magnetic resonant imaging scan revealed haematoma in post epidural space at the level of Lumbar 2 and 3. He underwent evacuation and posterior instrumentation on the 6th day. Spinal epidural haematoma should be included in the differential diagnosis of progressive spinal cord and nerve root compression in patients whom are receiving anticoagulant therapy. Prompt diagnosis and early surgical decompression would positively lead to a good outcome.
{"title":"Spinal epidural hematoma due to anticoagulant therapy: a case report and literature review","authors":"O. Htwe, A. S. Naicker, T. Pei","doi":"10.29333/EJGM/81908","DOIUrl":"https://doi.org/10.29333/EJGM/81908","url":null,"abstract":"This case report is to enlighten the awareness on spinal epidural haematoma due to warfarin. A 58-year-old man who had been on prophylactic anticoagulant therapy\u0000after aortic valve replacement since 1998, had presented with acute onset of reduced sensation and weakness in both lower extremities 3 days prior to the admission\u0000to our centre. His prothrombin time (PT) was 46.8 seconds, international normalized ratio (INR) was 5.11, and activated partial thromboplastin time (APTT) was 167.6\u0000seconds (control, 31.3-46.1 seconds). Magnetic resonant imaging scan revealed haematoma in post epidural space at the level of Lumbar 2 and 3. He underwent\u0000evacuation and posterior instrumentation on the 6th day. Spinal epidural haematoma should be included in the differential diagnosis of progressive spinal cord and\u0000nerve root compression in patients whom are receiving anticoagulant therapy. Prompt diagnosis and early surgical decompression would positively lead to a good\u0000outcome.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80364726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background:Lipomas are benign mesenchymal tumors of soft tissue that can be found anywhere in the body: However their presence in oral cavity is very rare (4.4%). Histopathologically lipomas are classified as simple lipomas and different variants. The present study describes the prevalence of oral lipomas with relation to patient’s age, their site of occurrence and histological pattern in Indian population.Methods:All cases of oral lipomas reported in the department of oral pathology and microbiology, N.I.M.S dental college Jaipur (India) from 2005 to 2017 for age, gender, site of occurrence, histopathological pattern and treatment mode were reviewed. The published case reports of oral lipomas reported in Indian patients from 1976 – 2017 also reviewed through pubmed by using MeSH word; oral lipoma and combined the data with the data of present study to analyze the prevalence and histopathological characteristic of oral lipomas in Indian population.Results:Total of 23 (14 males and 9 females) cases included in the study. The mean age was 34.3 years (range 17 – 71). The specific sites involved were buccal mucosa (n = 9) Tongue (n = 5) buccal vestibule (n = 2) Lip (n -= 3) Floor of mouth (n = 1), palate (n = 2) and retro molar pad (n = 1). Histopathological examination revealed 11 cases were diagnosed as simple lipoma, 6 cases were fibrolipoma, 2 cases were angiolipoma, 1 case each of osteolipoma, myxolioma, angiomyxolipoma and hibernoma. All cases treated with surgical excision only one case showed radiographical sign. This data was combined with the data of published cases (pubmed) of oral lipoma in Indian population.Conclusion:Oral lipomas are rare neoplasms of oral cavity; only 49 published cases have been found from 1976 – 2017 in Indian population. Oral lipoma should be considered as a differential diagnosis of oral soft tissue swelling. Surgical excision is the treatment of choice for all such tumors.
{"title":"Prevalence of oral lipomas in Indian population: Aninstitutional retrospective study of 12 years andanalysis of 49 published cases from 1976 – 2017reported in Indian patients","authors":"M. Bajpai, Manika Arora, Betina Chandolia","doi":"10.29333/EJGM/81904","DOIUrl":"https://doi.org/10.29333/EJGM/81904","url":null,"abstract":"Background:Lipomas are benign mesenchymal tumors of soft tissue that can be found anywhere in the body: However their presence in oral cavity is very rare (4.4%).\u0000Histopathologically lipomas are classified as simple lipomas and different variants. The present study describes the prevalence of oral lipomas with relation to patient’s\u0000age, their site of occurrence and histological pattern in Indian population.Methods:All cases of oral lipomas reported in the department of oral pathology and microbiology, N.I.M.S dental college Jaipur (India) from 2005 to 2017 for age,\u0000gender, site of occurrence, histopathological pattern and treatment mode were reviewed. The published case reports of oral lipomas reported in Indian patients from\u00001976 – 2017 also reviewed through pubmed by using MeSH word; oral lipoma and combined the data with the data of present study to analyze the prevalence and\u0000histopathological characteristic of oral lipomas in Indian population.Results:Total of 23 (14 males and 9 females) cases included in the study. The mean age was 34.3 years (range 17 – 71). The specific sites involved were buccal mucosa\u0000(n = 9) Tongue (n = 5) buccal vestibule (n = 2) Lip (n -= 3) Floor of mouth (n = 1), palate (n = 2) and retro molar pad (n = 1). Histopathological examination revealed 11\u0000cases were diagnosed as simple lipoma, 6 cases were fibrolipoma, 2 cases were angiolipoma, 1 case each of osteolipoma, myxolioma, angiomyxolipoma and hibernoma.\u0000All cases treated with surgical excision only one case showed radiographical sign. This data was combined with the data of published cases (pubmed) of oral lipoma in\u0000Indian population.Conclusion:Oral lipomas are rare neoplasms of oral cavity; only 49 published cases have been found from 1976 – 2017 in Indian population. Oral lipoma should be\u0000considered as a differential diagnosis of oral soft tissue swelling. Surgical excision is the treatment of choice for all such tumors.","PeriodicalId":12017,"journal":{"name":"European journal of general medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84625338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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