首页 > 最新文献

Evolution & Development最新文献

英文 中文
The Body Size and Fitness Match and Its Variability in Plastic Response to Temperature 体型和适合度匹配及其在温度下塑性反应的变异性
IF 2.6 3区 生物学 Q2 DEVELOPMENTAL BIOLOGY Pub Date : 2025-07-09 DOI: 10.1111/ede.70012
Antoni Żygadło, Agata Burzawa, Katarzyna Potera, Franek Sierpowski, Aleksandra Walczyńska

The evolution of the plastic response of organisms to environmental change remains one of the most challenging areas of biological research. Reasons for this include the complex nature of environmental cues and organismal responses, the energetic costs behind phenotypic plasticity performed under different conditions, and the individual capacity to respond, which depends on many developmental factors. A special case is the plastic body size response to temperature, the temperature-size rule (TSR). We used eight experimental populations of the rotifer Lecane inermis and measured body size and population growth rate r over a wide thermal range to investigate (i) the thermal conditions under which rotifers perform the TSR or canalize their body size (= no plasticity) and how this relates to fitness, and (ii) whether this response varies with organismal thermal preferences. We found a relationship between body size and fitness, confirming that the TSR is only performed within a certain thermal range, beyond which body size is canalized. We did not find the expected relationship between the strength of the TSR and the range of thermal tolerance, but our results do not allow us to reject the existence of such a relationship. Furthermore, we found a high repeatability of the parameters informing thermal tolerance compared to previous studies, reflecting a substantial degree of developmental constancy in the context of the organism's preference for temperature. We describe the special case of plasticity versus canalization for body size response to optimal and suboptimal temperatures in organisms that differ in their thermal tolerance.

生物对环境变化的塑性反应的进化仍然是生物学研究中最具挑战性的领域之一。原因包括环境线索和有机体反应的复杂性,在不同条件下表现的表型可塑性背后的能量成本,以及个体的反应能力,这取决于许多发育因素。一个特殊的情况是塑料体尺寸对温度的响应,即温度-尺寸规则(TSR)。我们使用了8个实验种群Lecane inermis,并测量了在广泛的热范围内的体型和种群增长率r,以研究(i)轮虫进行TSR或调节体型(=无可塑性)的热条件及其与适应性的关系,以及(ii)这种反应是否随机体热偏好而变化。我们发现了体型和健康之间的关系,证实了TSR只在一定的热范围内进行,超过这个热范围,体型就会被限制。我们没有发现TSR强度与热容范围之间的预期关系,但我们的结果不允许我们拒绝这种关系的存在。此外,与之前的研究相比,我们发现与热耐受性相关的参数具有很高的重复性,这反映了生物对温度偏好背景下的很大程度的发育稳定性。我们描述了塑性与管道化的特殊情况下,身体大小对最佳和次优温度的反应,在不同的生物体的热耐受性。
{"title":"The Body Size and Fitness Match and Its Variability in Plastic Response to Temperature","authors":"Antoni Żygadło,&nbsp;Agata Burzawa,&nbsp;Katarzyna Potera,&nbsp;Franek Sierpowski,&nbsp;Aleksandra Walczyńska","doi":"10.1111/ede.70012","DOIUrl":"https://doi.org/10.1111/ede.70012","url":null,"abstract":"<div>\u0000 \u0000 <p>The evolution of the plastic response of organisms to environmental change remains one of the most challenging areas of biological research. Reasons for this include the complex nature of environmental cues and organismal responses, the energetic costs behind phenotypic plasticity performed under different conditions, and the individual capacity to respond, which depends on many developmental factors. A special case is the plastic body size response to temperature, the temperature-size rule (TSR). We used eight experimental populations of the rotifer <i>Lecane inermis</i> and measured body size and population growth rate <i>r</i> over a wide thermal range to investigate (i) the thermal conditions under which rotifers perform the TSR or canalize their body size (= no plasticity) and how this relates to fitness, and (ii) whether this response varies with organismal thermal preferences. We found a relationship between body size and fitness, confirming that the TSR is only performed within a certain thermal range, beyond which body size is canalized. We did not find the expected relationship between the strength of the TSR and the range of thermal tolerance, but our results do not allow us to reject the existence of such a relationship. Furthermore, we found a high repeatability of the parameters informing thermal tolerance compared to previous studies, reflecting a substantial degree of developmental constancy in the context of the organism's preference for temperature. We describe the special case of plasticity versus canalization for body size response to optimal and suboptimal temperatures in organisms that differ in their thermal tolerance.</p></div>","PeriodicalId":12083,"journal":{"name":"Evolution & Development","volume":"27 3","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144589913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The rx3 Gene Contributes to the Evolution of Eye Loss in the Cavefish Astyanax mexicanus rx3基因与洞穴鱼失明的进化有关
IF 2.6 3区 生物学 Q2 DEVELOPMENTAL BIOLOGY Pub Date : 2025-06-30 DOI: 10.1111/ede.70011
Devin Shennard, Itzel Sifuentes-Romero, Rianna Ambosie, Jennah Abdelaziz, Erik R. Duboue, Johanna E. Kowalko

Uncovering mechanisms by which sensory systems evolve is critical for understanding how organisms adapt to a novel environment. Astyanax mexicanus is a species of fish with populations of surface fish, which inhabit rivers and streams, and cavefish, which have adapted to life within caves. Cavefish have evolved sensory system changes relative to their surface fish counterparts, providing an opportunity to investigate mechanisms underlying sensory system evolution. Here, we report the role of the gene retinal homeobox 3 (rx3) in cavefish eye evolution. We generated surface fish with putative loss-of-function mutations in the rx3 gene using CRISPR-Cas9 to determine the role of this gene in eye development in this species. These rx3 mutant surface fish fail to develop eyes, demonstrating that rx3 is required for surface fish eye development. Further, rx3 mutant surface fish exhibit altered behaviors relative to wild-type surface fish, suggesting that the loss of eyes impacts sensory-dependent behaviors. Finally, eye development is altered in cave-surface hybrid fish that inherit the mutant allele of rx3 from surface fish relative to siblings that inherit a wild-type surface fish rx3 allele, suggesting that cis-regulatory variation at the rx3 locus contributes to eye size evolution in cavefish. Together, these findings demonstrate that, as in other species, rx3 is required for eye development in A. mexicanus. Moreover, they suggest that variation at the rx3 locus plays a role in the evolved reduction of eye size in cavefish, shedding light on the genetic mechanisms underlying sensory system evolution in response to extreme environmental changes.

揭示感觉系统进化的机制对于理解生物体如何适应新环境至关重要。墨西哥Astyanax mexicanus是一种鱼类,有栖息在河流和溪流中的表层鱼,也有适应洞穴生活的洞穴鱼。洞穴鱼相对于它们的表层鱼类已经进化出了感觉系统的变化,这为研究感觉系统进化的机制提供了机会。在这里,我们报道了基因视网膜同源盒3 (rx3)在洞穴鱼眼睛进化中的作用。我们使用CRISPR-Cas9技术培育了rx3基因假定功能缺失突变的表面鱼,以确定该基因在该物种眼睛发育中的作用。这些rx3突变的水面鱼不能发育眼睛,这表明rx3是水面鱼眼睛发育所必需的。此外,rx3突变的表层鱼表现出与野生型表层鱼不同的行为,这表明眼睛的丧失影响了感觉依赖的行为。最后,与继承野生型表面鱼rx3等位基因的兄弟姐妹相比,遗传了表面鱼rx3突变等位基因的洞穴-表面杂交鱼的眼睛发育发生了改变,这表明rx3位点的顺式调控变异有助于洞穴鱼眼睛大小的进化。综上所述,这些发现表明,与其他物种一样,rx3是墨西哥斑羚眼睛发育所必需的。此外,他们认为rx3基因座的变异在洞穴鱼眼睛变小的进化过程中发挥了作用,从而揭示了极端环境变化下感觉系统进化的遗传机制。
{"title":"The rx3 Gene Contributes to the Evolution of Eye Loss in the Cavefish Astyanax mexicanus","authors":"Devin Shennard,&nbsp;Itzel Sifuentes-Romero,&nbsp;Rianna Ambosie,&nbsp;Jennah Abdelaziz,&nbsp;Erik R. Duboue,&nbsp;Johanna E. Kowalko","doi":"10.1111/ede.70011","DOIUrl":"https://doi.org/10.1111/ede.70011","url":null,"abstract":"<p>Uncovering mechanisms by which sensory systems evolve is critical for understanding how organisms adapt to a novel environment. <i>Astyanax mexicanus</i> is a species of fish with populations of surface fish, which inhabit rivers and streams, and cavefish, which have adapted to life within caves. Cavefish have evolved sensory system changes relative to their surface fish counterparts, providing an opportunity to investigate mechanisms underlying sensory system evolution. Here, we report the role of the gene <i>retinal homeobox 3</i> (<i>rx3</i>) in cavefish eye evolution. We generated surface fish with putative loss-of-function mutations in the <i>rx3</i> gene using CRISPR-Cas9 to determine the role of this gene in eye development in this species. These <i>rx3</i> mutant surface fish fail to develop eyes, demonstrating that <i>rx3</i> is required for surface fish eye development. Further, <i>rx3</i> mutant surface fish exhibit altered behaviors relative to wild-type surface fish, suggesting that the loss of eyes impacts sensory-dependent behaviors. Finally, eye development is altered in cave-surface hybrid fish that inherit the mutant allele of <i>rx3</i> from surface fish relative to siblings that inherit a wild-type surface fish <i>rx3</i> allele, suggesting that cis-regulatory variation at the <i>rx3</i> locus contributes to eye size evolution in cavefish. Together, these findings demonstrate that, as in other species, <i>rx3</i> is required for eye development in <i>A. mexicanus</i>. Moreover, they suggest that variation at the <i>rx3</i> locus plays a role in the evolved reduction of eye size in cavefish, shedding light on the genetic mechanisms underlying sensory system evolution in response to extreme environmental changes.</p>","PeriodicalId":12083,"journal":{"name":"Evolution & Development","volume":"27 3","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ede.70011","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144514618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Monopodial and Sympodial Growth Modes in the Colonial Graptolithina (Hemichordata, Pterobranchia) 群笔石属(半纲,翼支亚目)的单足和联足生长模式
IF 2.6 3区 生物学 Q2 DEVELOPMENTAL BIOLOGY Pub Date : 2025-06-11 DOI: 10.1111/ede.70010
Jörg Maletz, Rudy Lerosey-Aubril

Two growth modes are recognized in colonial pterobranchs (Graptolithina): monopodial growth and sympodial growth. The earliest colonial Graptolithina likely developed through monopodial growth, a mode of colony formation well-documented in the extant graptolite Rhabdopleura normani. This growth involves a permanent terminal zooid and the sequential budding of additional zooids behind it, as the contractile stalk (gymnocaulus) of this terminal zooid elongates. This process is reflected in specific features of the secreted housing structure, the tubarium. Recently, monopodial growth was identified for the first time in a fossil taxon—the Cambrian dithecodendrid Tarnagraptus—based on tubarium characteristics, as no zooids were preserved. Monopodial growth also appears probable in other Cambrian taxa resembling Tarnagraptus, although evidence remains limited due to fragmentary materials. Sympodial growth, characterized by transient terminal zooids that are sequentially replaced as new buds form, is extensively documented in the fossil record of the Graptolithina. This growth mode characterizes the vast majority of Cambrian to Devonian Dendroidea and Graptoloidea. Phylogenetic evidence suggests sympodial growth evolved from monopodial growth in graptolithines, but the mechanisms underlying this evolutionary transition remain unclear.

蚁群翼枝有两种生长模式:单轴生长和合轴生长。最早的笔石类群可能是通过单足生长发展起来的,这是一种在现存的笔石Rhabdopleura normani中得到充分证明的群体形成模式。这种生长包括一个永久的末端类动物和它后面的其他类动物的连续出芽,因为这个末端类动物的可收缩的茎(裸子茎)拉长。这一过程反映在秘密住宅结构的具体特征上,即浴室。最近,在寒武纪双树endrid tarnagraptus化石分类中首次发现了单足生长,基于管状体特征,因为没有保存动物。在其他类似Tarnagraptus的寒武纪分类群中也可能出现单足生长,尽管由于碎片材料的原因证据仍然有限。在笔石纲的化石记录中广泛记录了以瞬时末端动物为特征的合胞生长,其特征是依次被新的芽形式所取代。寒武纪至泥盆纪的绝大多数树科和笔科都具有这种生长方式。系统发育证据表明,笔石属植物的联足生长是从单足生长进化而来的,但这种进化转变的机制尚不清楚。
{"title":"Monopodial and Sympodial Growth Modes in the Colonial Graptolithina (Hemichordata, Pterobranchia)","authors":"Jörg Maletz,&nbsp;Rudy Lerosey-Aubril","doi":"10.1111/ede.70010","DOIUrl":"https://doi.org/10.1111/ede.70010","url":null,"abstract":"<p>Two growth modes are recognized in colonial pterobranchs (Graptolithina): monopodial growth and sympodial growth. The earliest colonial Graptolithina likely developed through monopodial growth, a mode of colony formation well-documented in the extant graptolite <i>Rhabdopleura normani</i>. This growth involves a permanent terminal zooid and the sequential budding of additional zooids behind it, as the contractile stalk (<i>gymnocaulus</i>) of this terminal zooid elongates. This process is reflected in specific features of the secreted housing structure, the tubarium. Recently, monopodial growth was identified for the first time in a fossil taxon—the Cambrian dithecodendrid <i>Tarnagraptus</i>—based on tubarium characteristics, as no zooids were preserved. Monopodial growth also appears probable in other Cambrian taxa resembling <i>Tarnagraptus</i>, although evidence remains limited due to fragmentary materials. Sympodial growth, characterized by transient terminal zooids that are sequentially replaced as new buds form, is extensively documented in the fossil record of the Graptolithina. This growth mode characterizes the vast majority of Cambrian to Devonian Dendroidea and Graptoloidea. Phylogenetic evidence suggests sympodial growth evolved from monopodial growth in graptolithines, but the mechanisms underlying this evolutionary transition remain unclear.</p>","PeriodicalId":12083,"journal":{"name":"Evolution & Development","volume":"27 2","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ede.70010","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144256460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recruitment of Sugar Transport and Scent Volatile Genes for Prey Attraction in the Nectar Spoon of Heliamphora tatei 白桦花蜜匙中糖转运和气味挥发基因的募集及吸引猎物的研究
IF 2.6 3区 生物学 Q2 DEVELOPMENTAL BIOLOGY Pub Date : 2025-05-24 DOI: 10.1111/ede.70009
Sukuan Liu, Stacey D. Smith

Prey attraction is an integral component of the carnivorous syndrome, yet its molecular adaptations have remained largely unexplored. Our study utilized tissue-specific transcriptomic data from the South American marsh pitcher plant, Heliamphora tatei, to explore the molecular and developmental basis of prey attraction. Carnivorous plants often present specialized structures associated with prey attraction and in Heliamphora, that function is carried out by the nectar spoon, a colorful extension of the top of the pitcher that is densely covered in nectaries. Through comparisons of gene expression in the nectar spoon with the rest of the pitcher, we identified a suite of differentially expressed genes that likely contribute to prey attraction, including enzymes involved in volatile synthesis and sugar transporters. We found that one lineage of sugar transporters, the 14a clade of SWEETs (Sugars Will Eventually Be Exported Transporters), is highly upregulated in the nectar spoon and has evolved more rapidly in Sarraceniaceae, consistent with specialization for nectar transport as part of prey attraction. Among the genes related to volatile production, we found several enzymes best known for their role in floral scent. These results suggest that, similar to prey digestion, ancient genes are repurposed for novel functions during the transition to carnivory and may facilitate the repeated convergent origins of carnivory across angiosperms.

对猎物的吸引力是食肉动物综合症的一个组成部分,但其分子适应性在很大程度上仍未被探索。本研究利用南美沼泽猪笼草Heliamphora tatei的组织特异性转录组学数据,探索猎物吸引的分子和发育基础。食肉植物通常呈现出与吸引猎物有关的特殊结构,在Heliamphora中,这种功能是由花蜜勺来完成的,花蜜勺是水罐顶部的一个彩色延伸,上面密密麻麻地覆盖着蜜腺。通过比较花蜜勺和猪笼草其他部位的基因表达,我们发现了一组差异表达的基因,这些基因可能有助于吸引猎物,包括参与挥发性合成和糖转运的酶。我们发现糖转运蛋白的一个谱系,糖的14a分支(糖最终会被出口转运蛋白),在花蜜勺中高度上调,并且在Sarraceniaceae中进化得更快,这与作为猎物吸引的一部分的花蜜转运专业化是一致的。在与挥发物产生相关的基因中,我们发现了几种最著名的酶,它们在花香中起着重要作用。这些结果表明,与猎物消化类似,在向食肉动物过渡的过程中,古老的基因被重新用于新的功能,并可能促进跨被子植物食肉性的重复趋同起源。
{"title":"Recruitment of Sugar Transport and Scent Volatile Genes for Prey Attraction in the Nectar Spoon of Heliamphora tatei","authors":"Sukuan Liu,&nbsp;Stacey D. Smith","doi":"10.1111/ede.70009","DOIUrl":"https://doi.org/10.1111/ede.70009","url":null,"abstract":"<p>Prey attraction is an integral component of the carnivorous syndrome, yet its molecular adaptations have remained largely unexplored. Our study utilized tissue-specific transcriptomic data from the South American marsh pitcher plant, <i>Heliamphora tatei</i>, to explore the molecular and developmental basis of prey attraction. Carnivorous plants often present specialized structures associated with prey attraction and in <i>Heliamphora</i>, that function is carried out by the nectar spoon, a colorful extension of the top of the pitcher that is densely covered in nectaries. Through comparisons of gene expression in the nectar spoon with the rest of the pitcher, we identified a suite of differentially expressed genes that likely contribute to prey attraction, including enzymes involved in volatile synthesis and sugar transporters. We found that one lineage of sugar transporters, the 14a clade of <i>SWEET</i>s (Sugars Will Eventually Be Exported Transporters), is highly upregulated in the nectar spoon and has evolved more rapidly in Sarraceniaceae, consistent with specialization for nectar transport as part of prey attraction. Among the genes related to volatile production, we found several enzymes best known for their role in floral scent. These results suggest that, similar to prey digestion, ancient genes are repurposed for novel functions during the transition to carnivory and may facilitate the repeated convergent origins of carnivory across angiosperms.</p>","PeriodicalId":12083,"journal":{"name":"Evolution & Development","volume":"27 2","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ede.70009","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144126080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Evolution of Skull Shape in Boana faber Clade: Unraveling Heterochrony's Influence 白桦枝颅骨形状的演化:揭示异时性的影响
IF 2.6 3区 生物学 Q2 DEVELOPMENTAL BIOLOGY Pub Date : 2025-05-13 DOI: 10.1111/ede.70008
Daniel de Abreu e Melo-Moreira, Roberta Azeredo Murta-Fonseca, Alessandra Silveira Machado, Ricardo Tadeu Lopes, Luciana Barreto Nascimento

Variation in shape and size within a lineage, driven by developmental processes, plays a key role in diversification. Here, we explore the effects of allometry and heterochrony on the skull shape evolution during the post-metamorphic period of species within the Boana faber clade, which vary considerably in body size. We analyzed 61 skulls of specimens belonging to eight species of the Boana faber clade, in addition to two outgroups, through 2D geometric morphometric analyses taken from CT-Scan images. Our results demonstrated that skull shape is considerably impacted by the size, represented by centroid size, and this effect can be observed from ontogenetic and evolutionary perspectives. In this way, we accessed the ontogenetic trajectories of analysed species and, in light of the phylogenetic hypothesis of the clade, we discussed the observed variation based on the concept of heterochrony, suggesting that a peramorphic pattern has evolved in the group.

在一个谱系内,由发育过程驱动的形状和大小的变化在多样化中起着关键作用。在这里,我们探讨了异速生长和异时性对Boana faber分支中物种后变质期颅骨形状进化的影响,这些物种的体型差异很大。通过ct扫描图像的二维几何形态分析,我们分析了属于Boana faber分支的8个物种的61个头骨标本,以及两个外群。我们的研究结果表明,头骨形状受到质心大小的影响很大,这种影响可以从个体发生和进化的角度观察到。通过这种方式,我们获得了被分析物种的个体发育轨迹,并根据进化枝的系统发育假说,我们根据异时性的概念讨论了观察到的变化,表明该群体已经进化出了一种变质模式。
{"title":"The Evolution of Skull Shape in Boana faber Clade: Unraveling Heterochrony's Influence","authors":"Daniel de Abreu e Melo-Moreira,&nbsp;Roberta Azeredo Murta-Fonseca,&nbsp;Alessandra Silveira Machado,&nbsp;Ricardo Tadeu Lopes,&nbsp;Luciana Barreto Nascimento","doi":"10.1111/ede.70008","DOIUrl":"https://doi.org/10.1111/ede.70008","url":null,"abstract":"<p>Variation in shape and size within a lineage, driven by developmental processes, plays a key role in diversification. Here, we explore the effects of allometry and heterochrony on the skull shape evolution during the post-metamorphic period of species within the <i>Boana faber</i> clade, which vary considerably in body size. We analyzed 61 skulls of specimens belonging to eight species of the <i>Boana faber</i> clade, in addition to two outgroups, through 2D geometric morphometric analyses taken from CT-Scan images. Our results demonstrated that skull shape is considerably impacted by the size, represented by centroid size, and this effect can be observed from ontogenetic and evolutionary perspectives. In this way, we accessed the ontogenetic trajectories of analysed species and, in light of the phylogenetic hypothesis of the clade, we discussed the observed variation based on the concept of heterochrony, suggesting that a peramorphic pattern has evolved in the group.</p>","PeriodicalId":12083,"journal":{"name":"Evolution & Development","volume":"27 2","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ede.70008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143939545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Plasticity as a Sign of Developmental Bias in the Evolution of Gene Regulatory Networks 可塑性是基因调控网络进化中发育偏差的标志
IF 2.6 3区 生物学 Q2 DEVELOPMENTAL BIOLOGY Pub Date : 2025-04-18 DOI: 10.1111/ede.70007
Carlos Espinosa-Soto

Phenotypic plasticity is an organism's ability to produce a different phenotype in response to nongenetic perturbations such as environmental disturbances. Beneficial phenotypic plasticity can be important in evolution. After an environmental disturbance, it can delay extinction giving opportunity to the appearance of beneficial mutations. In addition, plasticity may also be one of the factors that define the course that evolution takes, for example, through genetic assimilation. This is a process in which a phenotype that initially appears as a plastic response becomes under genetic control. In the end, development of such a phenotype does not require the factor that originally induced it. Here, I use a model of the evolution of gene regulatory networks to study the range of conditions that allow the association between plasticity and the course of evolution. I assayed conditions like the difference between ancestral and optimum phenotypes, the difficulty to build the optimum phenotype, the complexity of the developmental system, mutation rate, strength of plasticity limitations, fitness advantage of the optima, and the similarity between the initially induced phenotype and the optimum. I found that populations that yield a beneficial phenotype through plasticity most often evolve a similar genetically determined phenotype under all the conditions that I assayed. I also identified conditions that facilitate evolution through genetic assimilation. Notwithstanding, even under less favorable circumstances, this form of evolution still confers easier access to a new genetically determined optimum.

表型可塑性是生物体在非遗传扰动(如环境扰动)下产生不同表型的能力。有益的表型可塑性在进化中可能很重要。在环境扰动之后,它可以延迟灭绝,给有益突变的出现提供机会。此外,可塑性也可能是决定进化过程的因素之一,例如,通过遗传同化。在这一过程中,最初表现为塑性反应的表型变成了受遗传控制的表型。最后,这种表型的发展不需要最初诱导它的因素。在这里,我使用基因调控网络的进化模型来研究允许可塑性和进化过程之间联系的条件范围。我分析了祖先表型与最优表型之间的差异、构建最优表型的难度、发育系统的复杂性、突变率、可塑性限制的强度、最优适应度优势以及初始诱导表型与最优表型之间的相似性等条件。我发现,在我分析的所有条件下,通过可塑性产生有益表型的种群通常会进化出相似的基因决定表型。我还发现了通过基因同化促进进化的条件。尽管如此,即使在不太有利的环境下,这种进化形式仍然使人们更容易达到由基因决定的新的最佳状态。
{"title":"Plasticity as a Sign of Developmental Bias in the Evolution of Gene Regulatory Networks","authors":"Carlos Espinosa-Soto","doi":"10.1111/ede.70007","DOIUrl":"https://doi.org/10.1111/ede.70007","url":null,"abstract":"<div>\u0000 \u0000 <p>Phenotypic plasticity is an organism's ability to produce a different phenotype in response to nongenetic perturbations such as environmental disturbances. Beneficial phenotypic plasticity can be important in evolution. After an environmental disturbance, it can delay extinction giving opportunity to the appearance of beneficial mutations. In addition, plasticity may also be one of the factors that define the course that evolution takes, for example, through genetic assimilation. This is a process in which a phenotype that initially appears as a plastic response becomes under genetic control. In the end, development of such a phenotype does not require the factor that originally induced it. Here, I use a model of the evolution of gene regulatory networks to study the range of conditions that allow the association between plasticity and the course of evolution. I assayed conditions like the difference between ancestral and optimum phenotypes, the difficulty to build the optimum phenotype, the complexity of the developmental system, mutation rate, strength of plasticity limitations, fitness advantage of the optima, and the similarity between the initially induced phenotype and the optimum. I found that populations that yield a beneficial phenotype through plasticity most often evolve a similar genetically determined phenotype under all the conditions that I assayed. I also identified conditions that facilitate evolution through genetic assimilation. Notwithstanding, even under less favorable circumstances, this form of evolution still confers easier access to a new genetically determined optimum.</p></div>","PeriodicalId":12083,"journal":{"name":"Evolution & Development","volume":"27 2","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143845974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does Covariation Between Cranial and Pelvic Shapes Alleviate the Obstetric Dilemma? Insights From a Brazilian Sample 颅和盆腔形状的共变是否减轻了产科困境?来自巴西样本的见解
IF 2.6 3区 生物学 Q2 DEVELOPMENTAL BIOLOGY Pub Date : 2025-04-01 DOI: 10.1111/ede.70005
Maria Rita Guedes Carvalho, Mercedes Okumura

Cranial and pelvic bones could have evolved in response to each other during human evolutionary history due to the increasingly tight fit between the baby's head and the mother's pelvis during delivery. A recently identified covariation pattern between these sets of bones and stature has shown important evidence of such an evolutionary trade-off, alleviating the chances of obstructed labor. Here, we tested the validity of this covariation pattern in a different sample, from a population with known high rates of C-section. 98 computed tomographies were used to perform statistical covariation tests (two-block partial least squares and ANOVA Procrustes) between pelvic and cranial shape, as well as other anthropometric variables, like stature, body mass, and BMI. Additionally, measurements were taken from cranial and pelvic bones for classic morphometric analyses. The results have shown an important sexual dimorphism in pelvic bones' shape but no correlation between them and stature or cranial size or shape. In terms of size, the sexual dimorphism on the true pelvis was also noticeable. The fact that the results obtained from this sample do not corroborate previous findings suggests the absence of this pattern in some populations. It also suggests that the current ideal rates of C-sections proposed by the World Health Organization might not be considering the existing diversity among human populations that may account for variable levels of difficulties in birth.

在人类进化史上,由于婴儿的头部和母亲的骨盆在分娩过程中越来越紧密地结合在一起,颅骨和骨盆可能是为了相互回应而进化的。最近发现的这些骨骼和身材之间的共同变异模式为这种进化权衡提供了重要证据,减少了难产的机会。在这里,我们在一个不同的样本中测试了这种共变模式的有效性,这个样本来自一个已知的高剖腹产率的人群。使用98张计算机断层扫描进行骨盆和颅骨形状以及其他人体测量变量(如身材、体重和BMI)之间的统计共变检验(双块偏最小二乘法和方差分析Procrustes)。此外,测量从颅骨和骨盆骨进行经典形态计量学分析。结果表明,骨盆骨的形状具有重要的性别二态性,但与身高或颅骨大小或形状之间没有相关性。就大小而言,真骨盆的两性二态性也很明显。从这个样本中获得的结果并不能证实先前的发现,这一事实表明在某些人群中没有这种模式。它还表明,目前世界卫生组织提出的理想剖腹产率可能没有考虑到人口的多样性,这种多样性可能导致不同程度的分娩困难。
{"title":"Does Covariation Between Cranial and Pelvic Shapes Alleviate the Obstetric Dilemma? Insights From a Brazilian Sample","authors":"Maria Rita Guedes Carvalho,&nbsp;Mercedes Okumura","doi":"10.1111/ede.70005","DOIUrl":"https://doi.org/10.1111/ede.70005","url":null,"abstract":"<div>\u0000 \u0000 <p>Cranial and pelvic bones could have evolved in response to each other during human evolutionary history due to the increasingly tight fit between the baby's head and the mother's pelvis during delivery. A recently identified covariation pattern between these sets of bones and stature has shown important evidence of such an evolutionary trade-off, alleviating the chances of obstructed labor. Here, we tested the validity of this covariation pattern in a different sample, from a population with known high rates of C-section. 98 computed tomographies were used to perform statistical covariation tests (two-block partial least squares and ANOVA Procrustes) between pelvic and cranial shape, as well as other anthropometric variables, like stature, body mass, and BMI. Additionally, measurements were taken from cranial and pelvic bones for classic morphometric analyses. The results have shown an important sexual dimorphism in pelvic bones' shape but no correlation between them and stature or cranial size or shape. In terms of size, the sexual dimorphism on the true pelvis was also noticeable. The fact that the results obtained from this sample do not corroborate previous findings suggests the absence of this pattern in some populations. It also suggests that the current ideal rates of C-sections proposed by the World Health Organization might not be considering the existing diversity among human populations that may account for variable levels of difficulties in birth.</p></div>","PeriodicalId":12083,"journal":{"name":"Evolution & Development","volume":"27 2","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143749422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ontogenetic Mechanisms of Differentiation in Two Salvia Species With Different Pollinators 两种不同传粉媒介鼠尾草的分化机制
IF 2.6 3区 生物学 Q2 DEVELOPMENTAL BIOLOGY Pub Date : 2025-03-28 DOI: 10.1111/ede.70006
Agustín Davies, Santiago Benitez-Vieyra

Shifts between pollinators are a major driver in the evolution and diversification of angiosperms and often involve major changes in flower morphology. These morphological differences typically originate during development, highlighting the importance of integrating ecological and developmental studies. Corolla tube length, in particular, is a key trait in specialized plant-pollinator interactions. Here, we compared flower development in two closely related Salvia species with contrasting corolla tube lengths: Salvia guaranitica, pollinated by hummingbirds, and Salvia stachydifolia, primarily pollinated by bees. We characterized developmental trajectories, floral development duration, and patterns of cell growth and proliferation. Both species shared similar allometric trajectories, differing only in their prolongation, suggesting ontogenetic scaling. However, S. guaranitica exhibited longer and faster corolla tube growth, resulting in a larger final size compared to S. stachydifolia. Corolla tube growth was linked to cell proliferation during the early stages of bud development and rapid anisotropic cell elongation in later stages. Additionally, we observed differences in anisotropic growth rates across basal, middle, and distal regions of the corolla tube. These findings suggest that shifts between pollination syndromes in Salvia species may occur without major changes to basic developmental patterns, but through ontogenetic scaling accompanied by heterochronic changes.

传粉者之间的转换是被子植物进化和多样化的主要驱动力,通常涉及花形态的重大变化。这些形态差异通常起源于发育过程,突出了整合生态学和发育研究的重要性。花冠筒长度是植物与传粉者相互作用的关键性状。在这里,我们比较了两种花冠管长度不同的近亲鼠尾草的花发育:由蜂鸟授粉的鼠尾草(Salvia guaranitica)和主要由蜜蜂授粉的水仙(Salvia stachydifolia)。我们描述了发育轨迹、花发育持续时间以及细胞生长和增殖的模式。这两个物种都有相似的异速生长轨迹,不同之处在于它们的长度,这表明了个体发生尺度。但瓜拉尼加的花冠管生长时间更长,生长速度更快,最终尺寸大于水仙。花冠管生长与芽发育早期的细胞增殖和后期的细胞快速各向异性伸长有关。此外,我们还观察到花冠筒基部、中部和远端区域各向异性生长速率的差异。这些发现表明,丹参传粉综合征之间的转变可能在基本发育模式没有重大变化的情况下发生,而是通过个体发生尺度变化伴随着异时性变化。
{"title":"Ontogenetic Mechanisms of Differentiation in Two Salvia Species With Different Pollinators","authors":"Agustín Davies,&nbsp;Santiago Benitez-Vieyra","doi":"10.1111/ede.70006","DOIUrl":"https://doi.org/10.1111/ede.70006","url":null,"abstract":"<div>\u0000 \u0000 <p>Shifts between pollinators are a major driver in the evolution and diversification of angiosperms and often involve major changes in flower morphology. These morphological differences typically originate during development, highlighting the importance of integrating ecological and developmental studies. Corolla tube length, in particular, is a key trait in specialized plant-pollinator interactions. Here, we compared flower development in two closely related <i>Salvia</i> species with contrasting corolla tube lengths: <i>Salvia guaranitica</i>, pollinated by hummingbirds, and <i>Salvia stachydifolia</i>, primarily pollinated by bees. We characterized developmental trajectories, floral development duration, and patterns of cell growth and proliferation. Both species shared similar allometric trajectories, differing only in their prolongation, suggesting ontogenetic scaling. However, <i>S. guaranitica</i> exhibited longer and faster corolla tube growth, resulting in a larger final size compared to <i>S. stachydifolia</i>. Corolla tube growth was linked to cell proliferation during the early stages of bud development and rapid anisotropic cell elongation in later stages. Additionally, we observed differences in anisotropic growth rates across basal, middle, and distal regions of the corolla tube. These findings suggest that shifts between pollination syndromes in <i>Salvia</i> species may occur without major changes to basic developmental patterns, but through ontogenetic scaling accompanied by heterochronic changes.</p></div>","PeriodicalId":12083,"journal":{"name":"Evolution & Development","volume":"27 2","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Conserved Somatic Sex Determination Cascade Instructs Trait-Specific Sexual Dimorphism in Horned Dung Beetles 一个保守的体细胞性别决定级联指示角蜣螂的性状特异性性别二态性。
IF 2.6 3区 生物学 Q2 DEVELOPMENTAL BIOLOGY Pub Date : 2025-03-19 DOI: 10.1111/ede.70004
London C. Mitchell, Armin P. Moczek, Erica M. Nadolski

Sex-specific trait expression represents a striking dimension of morphological variation within and across species. The mechanisms instructing sex-specific organ development have been well studied in a small number of insect model systems, suggesting striking conservation in some parts of the somatic sex determination pathway while hinting at possible evolutionary lability in others. However, further resolution of this phenomenon necessitates additional taxon sampling, particularly in groups in which sexual dimorphisms have undergone significant elaboration and diversification. Here, we functionally investigate the somatic sex determination pathway in the gazelle dung beetle Digitonthophagus gazella, an emerging model system in the study of the development and evolution of sexual dimorphisms. We find that RNA interference (RNAi) targeting transformer (tra) caused chromosomal females to develop morphological traits largely indistinguishable from those normally only observed in males, and that traRNAi is sufficient to induce splicing of the normally male-specific isoform of doublesex in chromosomal females, while leaving males unaffected. Further, intersexRNAi was found to phenocopy previously described RNAi phenotypes of doublesex in female but not male beetles. These findings match predictions derived from models of the sex determination cascade as developed largely through studies in Drosophila melanogaster. In contrast, efforts to target transformer2 via RNAi resulted in high juvenile mortality but did not appear to affect doublesex splicing, whereas RNAi targeting Sex-lethal and two putative orthologs of hermaphrodite yielded no obvious phenotypic modifications in either males or females, raising the possibility that the function of a subset of sex determination genes may be derived in select Diptera and thus nonrepresentative of their roles in other holometabolous orders. Our results help illuminate how the differential evolutionary lability of the somatic sex determination pathway has contributed to the extraordinary morphological diversification of sex-specific trait expression found in nature.

性别特异性性状表达代表了物种内部和物种间形态变异的显著维度。在少数昆虫模型系统中,指示性别特异性器官发育的机制已经得到了很好的研究,表明体细胞性别决定途径的某些部分具有惊人的保守性,同时暗示其他部分可能存在进化不稳定性。然而,进一步解决这一现象需要额外的分类群取样,特别是在性别二态性经历了显著的细化和多样化的群体中。本文对瞪羚蜣螂(Digitonthophagus gazella)的体细胞性别决定途径进行了功能性研究,这是一种研究两性异形发育和进化的新兴模式系统。我们发现,靶向变形体(tra)的RNA干扰(RNAi)导致染色体雌性产生与通常仅在雄性中观察到的形态特征在很大程度上无法区分,并且traRNAi足以诱导染色体雌性中正常雄性特异性双性染色体异构体的剪接,而雄性不受影响。此外,intersexRNAi被发现在雌性而不是雄性甲虫中复制了先前描述的双性昆虫的RNAi表型。这些发现与性别决定级联模型的预测相吻合,这些模型主要是通过对黑腹果蝇的研究而发展起来的。相比之下,通过RNAi靶向transformer2的努力导致了高幼虫死亡率,但似乎没有影响双性剪接,而RNAi靶向性致死性和两种假定的雌雄同体同源物在雄性或雌性中都没有产生明显的表型改变,这提高了一种可能性,即性别决定基因子集的功能可能来源于选择的双翅目,因此不代表它们在其他全变性目中的作用。我们的研究结果有助于阐明体细胞性别决定途径的差异进化稳定性如何促成了自然界中发现的性别特异性性状表达的非凡形态多样化。
{"title":"A Conserved Somatic Sex Determination Cascade Instructs Trait-Specific Sexual Dimorphism in Horned Dung Beetles","authors":"London C. Mitchell,&nbsp;Armin P. Moczek,&nbsp;Erica M. Nadolski","doi":"10.1111/ede.70004","DOIUrl":"10.1111/ede.70004","url":null,"abstract":"<p>Sex-specific trait expression represents a striking dimension of morphological variation within and across species. The mechanisms instructing sex-specific organ development have been well studied in a small number of insect model systems, suggesting striking conservation in some parts of the somatic sex determination pathway while hinting at possible evolutionary lability in others. However, further resolution of this phenomenon necessitates additional taxon sampling, particularly in groups in which sexual dimorphisms have undergone significant elaboration and diversification. Here, we functionally investigate the somatic sex determination pathway in the gazelle dung beetle <i>Digitonthophagus gazella</i>, an emerging model system in the study of the development and evolution of sexual dimorphisms. We find that RNA interference (RNAi) targeting <i>transformer (tra)</i> caused chromosomal females to develop morphological traits largely indistinguishable from those normally only observed in males, and that <i>tra</i><sup>RNAi</sup> is sufficient to induce splicing of the normally male-specific isoform of <i>doublesex</i> in chromosomal females, while leaving males unaffected. Further, <i>intersex</i><sup>RNAi</sup> was found to phenocopy previously described RNAi phenotypes of <i>doublesex</i> in female but not male beetles. These findings match predictions derived from models of the sex determination cascade as developed largely through studies in <i>Drosophila melanogaster</i>. In contrast, efforts to target <i>transformer2</i> via RNAi resulted in high juvenile mortality but did not appear to affect <i>doublesex</i> splicing, whereas RNAi targeting <i>Sex-lethal</i> and two putative orthologs of <i>hermaphrodite</i> yielded no obvious phenotypic modifications in either males or females, raising the possibility that the function of a subset of sex determination genes may be derived in select Diptera and thus nonrepresentative of their roles in other holometabolous orders. Our results help illuminate how the differential evolutionary lability of the somatic sex determination pathway has contributed to the extraordinary morphological diversification of sex-specific trait expression found in nature.</p>","PeriodicalId":12083,"journal":{"name":"Evolution & Development","volume":"27 1","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11923317/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genetic Mapping of Orofacial Traits Reveals a Single Genomic Region Associated With Differences in Multiple Parameters of Jaw Size Between Astyanax mexicanus Surface and Cavefish 墨西哥Astyanax和洞穴鱼口面部特征的遗传定位揭示了与颚大小多个参数差异相关的单个基因组区域。
IF 2.6 3区 生物学 Q2 DEVELOPMENTAL BIOLOGY Pub Date : 2025-02-20 DOI: 10.1111/ede.70003
Amanda K. Powers, Alleigh Amaismeier, Kathryn Thiel, William Anyonge, Suzanne E. McGaugh, Tyler E. Boggs, Clifford J. Tabin, Joshua B. Gross

The regulation of bone size is a poorly understood and complex developmental process. Evolutionary models can enable insight through interrogation of the developmental and molecular underpinnings of natural variation in bone size and shape. Here, we examine the Mexican tetra (Astyanax mexicanus), a species of teleost fish comprising of an extant river-dwelling surface fish and obligate cave-dwelling fish. These divergent morphs have evolved for thousands of years in drastically different habitats, which have led to diverse phenotypic differences. Among many craniofacial aberrations, cavefish harbor a wider gape, an underbite, and larger jaws compared to surface-dwelling morphs. Morphotypes are inter-fertile, allowing quantitative genetic analyses in F2 pedigrees derived from surface × cavefish crosses. Here, we used quantitative trait locus (QTL) analysis to determine the genetic basis of jaw size. Strikingly, we discovered a single genomic region associated with several jaw size metrics. Future work identifying genetic lesions that explain differences in jaw development will provide new insight to the mechanisms driving bone size differences across vertebrate taxa.

骨大小的调节是一个鲜为人知的复杂的发育过程。进化模型可以通过询问骨骼大小和形状自然变化的发育和分子基础来实现洞察力。在这里,我们研究了墨西哥四鱼(Astyanax mexicanus),一种硬骨鱼,由现存的河面鱼和专性穴居鱼组成。这些不同的形态在截然不同的栖息地中进化了数千年,导致了不同的表型差异。在许多颅面畸形中,与生活在水面上的鱼类相比,洞穴鱼有更宽的开口、下咬合和更大的颚。形态型是间可育的,允许对来自面穴鱼杂交的F2家系进行定量遗传分析。在这里,我们使用数量性状位点(QTL)分析来确定颌骨大小的遗传基础。引人注目的是,我们发现了一个与几个颌骨尺寸指标相关的单一基因组区域。未来的工作将确定解释颌骨发育差异的遗传病变,这将为脊椎动物类群之间骨骼大小差异的机制提供新的见解。
{"title":"Genetic Mapping of Orofacial Traits Reveals a Single Genomic Region Associated With Differences in Multiple Parameters of Jaw Size Between Astyanax mexicanus Surface and Cavefish","authors":"Amanda K. Powers,&nbsp;Alleigh Amaismeier,&nbsp;Kathryn Thiel,&nbsp;William Anyonge,&nbsp;Suzanne E. McGaugh,&nbsp;Tyler E. Boggs,&nbsp;Clifford J. Tabin,&nbsp;Joshua B. Gross","doi":"10.1111/ede.70003","DOIUrl":"10.1111/ede.70003","url":null,"abstract":"<p>The regulation of bone size is a poorly understood and complex developmental process. Evolutionary models can enable insight through interrogation of the developmental and molecular underpinnings of natural variation in bone size and shape. Here, we examine the Mexican tetra (<i>Astyanax mexicanus</i>), a species of teleost fish comprising of an extant river-dwelling surface fish and obligate cave-dwelling fish. These divergent morphs have evolved for thousands of years in drastically different habitats, which have led to diverse phenotypic differences. Among many craniofacial aberrations, cavefish harbor a wider gape, an underbite, and larger jaws compared to surface-dwelling morphs. Morphotypes are inter-fertile, allowing quantitative genetic analyses in F<sub>2</sub> pedigrees derived from surface × cavefish crosses. Here, we used quantitative trait locus (QTL) analysis to determine the genetic basis of jaw size. Strikingly, we discovered a single genomic region associated with several jaw size metrics. Future work identifying genetic lesions that explain differences in jaw development will provide new insight to the mechanisms driving bone size differences across vertebrate taxa.</p>","PeriodicalId":12083,"journal":{"name":"Evolution & Development","volume":"28 1","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12353297/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143457413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Evolution & Development
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1