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Impact of mental health disorders and perioperative outcomes following anterior cervical discectomy and fusion (ACDF): a national inpatient analysis. 前路颈椎椎间盘切除术和融合术(ACDF)后精神健康障碍和围手术期结果的影响:一项全国住院患者分析
IF 2.7 3区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2026-01-20 DOI: 10.1007/s00586-025-09728-6
Mitchell Ng, Leonidas Mastrokostas, Paul Mastrokostas, Gregorio Baek, Jonathan Dalton, Adam Fano, Alec Giakas, Rajendra Singh, Afshin Razi, Arya Varthi, Mark Kurd, Zachary Wilt, Daniel Fassett, Alan Hilibrand, Alexander Vaccaro, Gregory Schroeder, Christopher Kepler, Andrew Alvarez

Purpose: Mental health disorders have been shown to influence surgical outcomes, yet their effects on cervical spine surgery remain incompletely defined. This study evaluated the impact of depression and psychotic disorders on (1) perioperative complications, (2) discharge disposition, and (3) hospital resource utilization following anterior cervical discectomy and fusion (ACDF).

Methods: The National Inpatient Sample (NIS) was queried for adult ACDF admissions from 2016 to 2022. Patients were classified into those with either no mental illness, depression, or psychotic disorder. Medical/surgical complications, dysphagia, and overall adverse events were extracted using ICD-10 diagnosis codes. Discharge status, inpatient mortality, costs, and length of stay were also evaluated across all cohorts. Subsequent analyses were adjusted for demographics, Elixhauser comorbidity index, hospital characteristics, and levels fused. Fusion level was included as a categorical covariate (single-level vs. multilevel) in all adjusted regression models. Multivariable logistic regression estimated adjusted odds ratios for complications/discharge outcomes, while weighted linear models compared/contrasted healthcare utilization with statistical significance set at P < 0.05.

Results: 376,130 inpatient ACDFs were identified (64,020 with depression, 11,255 with psychotic disorders). Depression was associated with increased cardiovascular complications (OR 1.28, 95% CI 1.16-1.41), dysphagia (OR 1.09, 95% CI 1.02-1.18), and non-routine discharge (OR 1.15, 95% CI 1.09-1.21). Psychotic disorders were associated with increased rates of cardiovascular events (OR 1.29, 95% CI 1.04-1.59), mechanical complications (OR 1.36, 95% CI 1.01-1.83), and non-routine discharge (OR 1.47, 95% CI 1.32-1.64). Both mean costs and length of stay were likewise higher in patients with mental disorders (P < 0.001).

Conclusion: Mental health disorders are associated with increased postoperative complications, non-routine discharge, and healthcare utilization following ACDF. Appropriate diagnosis, management, and preoperative optimization may improve outcomes in this patient population.

目的:精神健康障碍已被证明会影响手术结果,但其对颈椎手术的影响仍不完全明确。本研究评估抑郁和精神障碍对(1)围手术期并发症、(2)出院处置和(3)前路颈椎椎间盘切除术融合术后医院资源利用的影响。方法:对2016 - 2022年成人ACDF入院的全国住院患者样本(NIS)进行查询。患者被分为无精神疾病、抑郁症和精神病三组。使用ICD-10诊断代码提取医疗/手术并发症、吞咽困难和总体不良事件。所有队列的出院状况、住院死亡率、费用和住院时间也被评估。随后的分析根据人口统计学、Elixhauser合并症指数、医院特征和融合水平进行调整。在所有调整后的回归模型中,融合水平被纳入分类协变量(单水平与多水平)。多变量logistic回归估计并发症/出院结果的校正优势比,而加权线性模型比较/对比医疗保健利用,P值具有统计学意义。结果:确定了376,130名住院ACDFs患者(64,020名抑郁症患者,11,255名精神障碍患者)。抑郁症与心血管并发症增加(OR 1.28, 95% CI 1.16-1.41)、吞咽困难(OR 1.09, 95% CI 1.02-1.18)和非常规出院(OR 1.15, 95% CI 1.09-1.21)相关。精神障碍与心血管事件(OR 1.29, 95% CI 1.04-1.59)、机械并发症(OR 1.36, 95% CI 1.01-1.83)和非常规出院(OR 1.47, 95% CI 1.32-1.64)增加相关。精神障碍患者的平均费用和住院时间同样更高(P结论:精神健康障碍与ACDF术后并发症、非常规出院和医疗保健利用率增加有关。适当的诊断、管理和术前优化可以改善这类患者的预后。
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引用次数: 0
3D virtual models versus 2D imaging in preoperative planning for spinal En bloc resections: a comparative cohort study. 三维虚拟模型与二维成像在脊柱整体切除术前计划中的对比:一项比较队列研究
IF 2.7 3区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2026-01-13 DOI: 10.1007/s00586-025-09729-5
Miki Shikanai, Aditya Swaminathan, Ilijana Sumonja Zisakis, Siu Li Boo, Melvin Grainger, Huma Haseeb, Thomas Land, Jonathan Shadwell, Hussein Shoukry, Wai Cheong Soon, Sophie Walters, Marcin Czyz
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引用次数: 0
Climatic and clinical risk factors for surgical site infection following spine fusion surgery: a large-scale big data analysis. 脊柱融合术后手术部位感染的气候和临床危险因素:大规模大数据分析
IF 2.7 3区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2026-01-10 DOI: 10.1007/s00586-025-09643-w
Myung-Sup Ko, Soyeong Park, Young-Hoon Kim, Yohan Ko, Kee-Yong Ha, Hyung-Youl Park, Young-Il Ko, Yunseong Kim, Sangjun Park, Youngho Lee, Sang-Il Kim
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引用次数: 0
A modified bone cement pusher for percutaneous vertebroplasty combined with multi-target negative pressure rotary-cutting technique in puncture biopsy for bone tumors. 经皮椎体成形术中改良骨水泥推力器联合多靶点负压旋转切割技术在骨肿瘤穿刺活检中的应用。
IF 2.7 3区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2026-01-09 DOI: 10.1007/s00586-025-09733-9
Zhengyong Tao, Zongqiang Yang, Xiaobin Ma, Jiandang Shi, NingKui Niu
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引用次数: 0
Intervertebral disc distraction stiffness predicts endplate subsidence following transforaminal interbody cage expansion: an ex vivo study. 椎间盘牵张刚度预测椎间孔椎间笼扩张后终板沉降:一项离体研究。
IF 2.7 3区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2026-01-09 DOI: 10.1007/s00586-025-09715-x
Kay A Raftery, Hannah Levy, Rananjay Singh, Mohammed Madi, Thomas D Slater, Antony J Crossman, Angela E Kedgley, Brett A Freedman, Nicolas Newell
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引用次数: 0
Long-term impact of gastrointestinal risk stratification management on perioperative digestive complications in elderly osteoporotic vertebral fracture patients: a 10-year interrupted time series study. 胃肠风险分层管理对老年骨质疏松性椎体骨折患者围手术期消化并发症的长期影响:一项10年中断时间序列研究
IF 2.7 3区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2026-01-09 DOI: 10.1007/s00586-025-09687-y
Wenli Ge, Xiaochun Fan, Shuai Wang, Lin Wei, Lu Hu, Guangrong Ji
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引用次数: 0
The ELEVATE-LBP consortium: exercise & evidence to lead effective vital action in translating excellence for low back pain prevention. 升高- lbp联盟:运动和证据,引导有效的重要行动,转化卓越的腰痛预防。
IF 2.7 3区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2026-01-09 DOI: 10.1007/s00586-025-09674-3
Liba Sheeran, Suzanne McIlroy, Arnold Y L Wong, David B Anderson, Dino Samartzis, Liedewij Bogaert, Bruno Domokos, Christoph Spang, Maryse Fortin, Paul W Hodges, Mario Bizzini, Jiří Dvořák
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引用次数: 0
Comparative analysis of surgical outcomes and prognostic factors between primary and recurrent sacral chordomas. 原发性与复发性骶脊索瘤手术效果及预后因素的比较分析。
IF 2.7 3区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2026-01-09 DOI: 10.1007/s00586-026-09736-0
Junxiao Li, Zhilong Shen, Pengru Wang, Jiawei Zhou, Jianru Xiao, Wei Xu
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引用次数: 0
The effect of exercıse program on exercıse perceptıon and fear of movement ın low back paın. exercıse计划对exercıse perceptıon和运动恐惧的影响ın下背paın。
IF 2.7 3区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2026-01-09 DOI: 10.1007/s00586-025-09720-0
Mine Arğali Deniz, Burcu Özüberk, Feray Soyupek
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引用次数: 0
Four-level pedicle subtraction osteotomy for severe rigid thoracic hyperkyphosis: a technical case report. 四节段椎弓根减截骨术治疗重度刚性胸后凸症一例技术病例报告。
IF 2.7 3区 医学 Q2 CLINICAL NEUROLOGY Pub Date : 2026-01-08 DOI: 10.1007/s00586-025-09734-8
Cécile Roscop, Anouar Bourghli, Daniel Larrieu, Louis Boissière, Ibrahim Obeid

Study design: Technical case report.

Introduction: Severe thoracic hyperkyphosis caused by multiple osteoporotic fractures can lead to significant disability. When deformities are rigid, surgical correction may be required. This report describes a rare case of four-level pedicle subtraction osteotomy (PSO) to address a fixed deformity, with focus on technique, outcomes, and complications.

Case presentation: A 65-year-old female with Scheuermann's disease developed progressive thoracic hyperkyphosis due to osteoporotic vertebral fractures. Radiographs showed a rigid kyphosis of 130.3°. The patient underwent a two-stage surgery: cement-augmented instrumentation (T2-L3), followed by contiguous PSOs from T6 to T9. Neurophysiological monitoring was used throughout.

Results: Kyphosis was corrected from 130.3° to 48°. Postoperatively, the patient developed progressive lower limb weakness due to spinal cord kinking. Revision surgery allowed neurological recovery. At two years, radiological parameters remained stable, and the patient reported reduced pain, improved mobility, and restored quality of life.

Conclusion: Four-level PSO can be an effective treatment for severe rigid thoracic hyperkyphosis in osteoporotic patients. Although technically demanding and associated with potential complications, careful planning and staged correction can result in successful outcomes.

Level of evidence: IV (Case Report).

研究设计:技术案例报告。简介:多发性骨质疏松性骨折引起的严重胸后凸症可导致严重的残疾。当畸形是刚性的,可能需要手术矫正。本报告描述了一例罕见的四节段椎弓根减截骨术(PSO)治疗固定畸形的病例,重点介绍了技术、结果和并发症。病例介绍:一名65岁女性伴有舒尔曼病,由于骨质疏松性椎体骨折而发展为进行性胸后凸症。x线片显示刚性后凸130.3°。患者接受了两期手术:骨水泥增强内固定(T2-L3),随后在T6至T9连续进行pso。全程神经生理监测。结果:后凸由130.3°矫正至48°。术后,由于脊髓扭结,患者出现进行性下肢无力。翻修手术使神经系统恢复。两年后,放射学参数保持稳定,患者报告疼痛减轻,活动能力改善,生活质量恢复。结论:四级PSO可有效治疗骨质疏松症患者重度刚性胸后凸症。尽管在技术上要求很高,并且伴有潜在的并发症,但仔细的计划和分阶段的矫正可以获得成功的结果。证据等级:IV(病例报告)。
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引用次数: 0
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European Spine Journal
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