Pub Date : 2026-01-20DOI: 10.1007/s00586-025-09728-6
Mitchell Ng, Leonidas Mastrokostas, Paul Mastrokostas, Gregorio Baek, Jonathan Dalton, Adam Fano, Alec Giakas, Rajendra Singh, Afshin Razi, Arya Varthi, Mark Kurd, Zachary Wilt, Daniel Fassett, Alan Hilibrand, Alexander Vaccaro, Gregory Schroeder, Christopher Kepler, Andrew Alvarez
Purpose: Mental health disorders have been shown to influence surgical outcomes, yet their effects on cervical spine surgery remain incompletely defined. This study evaluated the impact of depression and psychotic disorders on (1) perioperative complications, (2) discharge disposition, and (3) hospital resource utilization following anterior cervical discectomy and fusion (ACDF).
Methods: The National Inpatient Sample (NIS) was queried for adult ACDF admissions from 2016 to 2022. Patients were classified into those with either no mental illness, depression, or psychotic disorder. Medical/surgical complications, dysphagia, and overall adverse events were extracted using ICD-10 diagnosis codes. Discharge status, inpatient mortality, costs, and length of stay were also evaluated across all cohorts. Subsequent analyses were adjusted for demographics, Elixhauser comorbidity index, hospital characteristics, and levels fused. Fusion level was included as a categorical covariate (single-level vs. multilevel) in all adjusted regression models. Multivariable logistic regression estimated adjusted odds ratios for complications/discharge outcomes, while weighted linear models compared/contrasted healthcare utilization with statistical significance set at P < 0.05.
Results: 376,130 inpatient ACDFs were identified (64,020 with depression, 11,255 with psychotic disorders). Depression was associated with increased cardiovascular complications (OR 1.28, 95% CI 1.16-1.41), dysphagia (OR 1.09, 95% CI 1.02-1.18), and non-routine discharge (OR 1.15, 95% CI 1.09-1.21). Psychotic disorders were associated with increased rates of cardiovascular events (OR 1.29, 95% CI 1.04-1.59), mechanical complications (OR 1.36, 95% CI 1.01-1.83), and non-routine discharge (OR 1.47, 95% CI 1.32-1.64). Both mean costs and length of stay were likewise higher in patients with mental disorders (P < 0.001).
Conclusion: Mental health disorders are associated with increased postoperative complications, non-routine discharge, and healthcare utilization following ACDF. Appropriate diagnosis, management, and preoperative optimization may improve outcomes in this patient population.
目的:精神健康障碍已被证明会影响手术结果,但其对颈椎手术的影响仍不完全明确。本研究评估抑郁和精神障碍对(1)围手术期并发症、(2)出院处置和(3)前路颈椎椎间盘切除术融合术后医院资源利用的影响。方法:对2016 - 2022年成人ACDF入院的全国住院患者样本(NIS)进行查询。患者被分为无精神疾病、抑郁症和精神病三组。使用ICD-10诊断代码提取医疗/手术并发症、吞咽困难和总体不良事件。所有队列的出院状况、住院死亡率、费用和住院时间也被评估。随后的分析根据人口统计学、Elixhauser合并症指数、医院特征和融合水平进行调整。在所有调整后的回归模型中,融合水平被纳入分类协变量(单水平与多水平)。多变量logistic回归估计并发症/出院结果的校正优势比,而加权线性模型比较/对比医疗保健利用,P值具有统计学意义。结果:确定了376,130名住院ACDFs患者(64,020名抑郁症患者,11,255名精神障碍患者)。抑郁症与心血管并发症增加(OR 1.28, 95% CI 1.16-1.41)、吞咽困难(OR 1.09, 95% CI 1.02-1.18)和非常规出院(OR 1.15, 95% CI 1.09-1.21)相关。精神障碍与心血管事件(OR 1.29, 95% CI 1.04-1.59)、机械并发症(OR 1.36, 95% CI 1.01-1.83)和非常规出院(OR 1.47, 95% CI 1.32-1.64)增加相关。精神障碍患者的平均费用和住院时间同样更高(P结论:精神健康障碍与ACDF术后并发症、非常规出院和医疗保健利用率增加有关。适当的诊断、管理和术前优化可以改善这类患者的预后。
{"title":"Impact of mental health disorders and perioperative outcomes following anterior cervical discectomy and fusion (ACDF): a national inpatient analysis.","authors":"Mitchell Ng, Leonidas Mastrokostas, Paul Mastrokostas, Gregorio Baek, Jonathan Dalton, Adam Fano, Alec Giakas, Rajendra Singh, Afshin Razi, Arya Varthi, Mark Kurd, Zachary Wilt, Daniel Fassett, Alan Hilibrand, Alexander Vaccaro, Gregory Schroeder, Christopher Kepler, Andrew Alvarez","doi":"10.1007/s00586-025-09728-6","DOIUrl":"https://doi.org/10.1007/s00586-025-09728-6","url":null,"abstract":"<p><strong>Purpose: </strong>Mental health disorders have been shown to influence surgical outcomes, yet their effects on cervical spine surgery remain incompletely defined. This study evaluated the impact of depression and psychotic disorders on (1) perioperative complications, (2) discharge disposition, and (3) hospital resource utilization following anterior cervical discectomy and fusion (ACDF).</p><p><strong>Methods: </strong>The National Inpatient Sample (NIS) was queried for adult ACDF admissions from 2016 to 2022. Patients were classified into those with either no mental illness, depression, or psychotic disorder. Medical/surgical complications, dysphagia, and overall adverse events were extracted using ICD-10 diagnosis codes. Discharge status, inpatient mortality, costs, and length of stay were also evaluated across all cohorts. Subsequent analyses were adjusted for demographics, Elixhauser comorbidity index, hospital characteristics, and levels fused. Fusion level was included as a categorical covariate (single-level vs. multilevel) in all adjusted regression models. Multivariable logistic regression estimated adjusted odds ratios for complications/discharge outcomes, while weighted linear models compared/contrasted healthcare utilization with statistical significance set at P < 0.05.</p><p><strong>Results: </strong>376,130 inpatient ACDFs were identified (64,020 with depression, 11,255 with psychotic disorders). Depression was associated with increased cardiovascular complications (OR 1.28, 95% CI 1.16-1.41), dysphagia (OR 1.09, 95% CI 1.02-1.18), and non-routine discharge (OR 1.15, 95% CI 1.09-1.21). Psychotic disorders were associated with increased rates of cardiovascular events (OR 1.29, 95% CI 1.04-1.59), mechanical complications (OR 1.36, 95% CI 1.01-1.83), and non-routine discharge (OR 1.47, 95% CI 1.32-1.64). Both mean costs and length of stay were likewise higher in patients with mental disorders (P < 0.001).</p><p><strong>Conclusion: </strong>Mental health disorders are associated with increased postoperative complications, non-routine discharge, and healthcare utilization following ACDF. Appropriate diagnosis, management, and preoperative optimization may improve outcomes in this patient population.</p>","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146003434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-13DOI: 10.1007/s00586-025-09729-5
Miki Shikanai, Aditya Swaminathan, Ilijana Sumonja Zisakis, Siu Li Boo, Melvin Grainger, Huma Haseeb, Thomas Land, Jonathan Shadwell, Hussein Shoukry, Wai Cheong Soon, Sophie Walters, Marcin Czyz
{"title":"3D virtual models versus 2D imaging in preoperative planning for spinal En bloc resections: a comparative cohort study.","authors":"Miki Shikanai, Aditya Swaminathan, Ilijana Sumonja Zisakis, Siu Li Boo, Melvin Grainger, Huma Haseeb, Thomas Land, Jonathan Shadwell, Hussein Shoukry, Wai Cheong Soon, Sophie Walters, Marcin Czyz","doi":"10.1007/s00586-025-09729-5","DOIUrl":"https://doi.org/10.1007/s00586-025-09729-5","url":null,"abstract":"","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145959093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-10DOI: 10.1007/s00586-025-09643-w
Myung-Sup Ko, Soyeong Park, Young-Hoon Kim, Yohan Ko, Kee-Yong Ha, Hyung-Youl Park, Young-Il Ko, Yunseong Kim, Sangjun Park, Youngho Lee, Sang-Il Kim
{"title":"Climatic and clinical risk factors for surgical site infection following spine fusion surgery: a large-scale big data analysis.","authors":"Myung-Sup Ko, Soyeong Park, Young-Hoon Kim, Yohan Ko, Kee-Yong Ha, Hyung-Youl Park, Young-Il Ko, Yunseong Kim, Sangjun Park, Youngho Lee, Sang-Il Kim","doi":"10.1007/s00586-025-09643-w","DOIUrl":"https://doi.org/10.1007/s00586-025-09643-w","url":null,"abstract":"","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145943029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-09DOI: 10.1007/s00586-025-09715-x
Kay A Raftery, Hannah Levy, Rananjay Singh, Mohammed Madi, Thomas D Slater, Antony J Crossman, Angela E Kedgley, Brett A Freedman, Nicolas Newell
{"title":"Intervertebral disc distraction stiffness predicts endplate subsidence following transforaminal interbody cage expansion: an ex vivo study.","authors":"Kay A Raftery, Hannah Levy, Rananjay Singh, Mohammed Madi, Thomas D Slater, Antony J Crossman, Angela E Kedgley, Brett A Freedman, Nicolas Newell","doi":"10.1007/s00586-025-09715-x","DOIUrl":"https://doi.org/10.1007/s00586-025-09715-x","url":null,"abstract":"","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145932914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-09DOI: 10.1007/s00586-025-09687-y
Wenli Ge, Xiaochun Fan, Shuai Wang, Lin Wei, Lu Hu, Guangrong Ji
{"title":"Long-term impact of gastrointestinal risk stratification management on perioperative digestive complications in elderly osteoporotic vertebral fracture patients: a 10-year interrupted time series study.","authors":"Wenli Ge, Xiaochun Fan, Shuai Wang, Lin Wei, Lu Hu, Guangrong Ji","doi":"10.1007/s00586-025-09687-y","DOIUrl":"https://doi.org/10.1007/s00586-025-09687-y","url":null,"abstract":"","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145932933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-09DOI: 10.1007/s00586-025-09674-3
Liba Sheeran, Suzanne McIlroy, Arnold Y L Wong, David B Anderson, Dino Samartzis, Liedewij Bogaert, Bruno Domokos, Christoph Spang, Maryse Fortin, Paul W Hodges, Mario Bizzini, Jiří Dvořák
{"title":"The ELEVATE-LBP consortium: exercise & evidence to lead effective vital action in translating excellence for low back pain prevention.","authors":"Liba Sheeran, Suzanne McIlroy, Arnold Y L Wong, David B Anderson, Dino Samartzis, Liedewij Bogaert, Bruno Domokos, Christoph Spang, Maryse Fortin, Paul W Hodges, Mario Bizzini, Jiří Dvořák","doi":"10.1007/s00586-025-09674-3","DOIUrl":"https://doi.org/10.1007/s00586-025-09674-3","url":null,"abstract":"","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145932912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-09DOI: 10.1007/s00586-025-09720-0
Mine Arğali Deniz, Burcu Özüberk, Feray Soyupek
{"title":"The effect of exercıse program on exercıse perceptıon and fear of movement ın low back paın.","authors":"Mine Arğali Deniz, Burcu Özüberk, Feray Soyupek","doi":"10.1007/s00586-025-09720-0","DOIUrl":"https://doi.org/10.1007/s00586-025-09720-0","url":null,"abstract":"","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145932947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-08DOI: 10.1007/s00586-025-09734-8
Cécile Roscop, Anouar Bourghli, Daniel Larrieu, Louis Boissière, Ibrahim Obeid
Study design: Technical case report.
Introduction: Severe thoracic hyperkyphosis caused by multiple osteoporotic fractures can lead to significant disability. When deformities are rigid, surgical correction may be required. This report describes a rare case of four-level pedicle subtraction osteotomy (PSO) to address a fixed deformity, with focus on technique, outcomes, and complications.
Case presentation: A 65-year-old female with Scheuermann's disease developed progressive thoracic hyperkyphosis due to osteoporotic vertebral fractures. Radiographs showed a rigid kyphosis of 130.3°. The patient underwent a two-stage surgery: cement-augmented instrumentation (T2-L3), followed by contiguous PSOs from T6 to T9. Neurophysiological monitoring was used throughout.
Results: Kyphosis was corrected from 130.3° to 48°. Postoperatively, the patient developed progressive lower limb weakness due to spinal cord kinking. Revision surgery allowed neurological recovery. At two years, radiological parameters remained stable, and the patient reported reduced pain, improved mobility, and restored quality of life.
Conclusion: Four-level PSO can be an effective treatment for severe rigid thoracic hyperkyphosis in osteoporotic patients. Although technically demanding and associated with potential complications, careful planning and staged correction can result in successful outcomes.
{"title":"Four-level pedicle subtraction osteotomy for severe rigid thoracic hyperkyphosis: a technical case report.","authors":"Cécile Roscop, Anouar Bourghli, Daniel Larrieu, Louis Boissière, Ibrahim Obeid","doi":"10.1007/s00586-025-09734-8","DOIUrl":"https://doi.org/10.1007/s00586-025-09734-8","url":null,"abstract":"<p><strong>Study design: </strong>Technical case report.</p><p><strong>Introduction: </strong>Severe thoracic hyperkyphosis caused by multiple osteoporotic fractures can lead to significant disability. When deformities are rigid, surgical correction may be required. This report describes a rare case of four-level pedicle subtraction osteotomy (PSO) to address a fixed deformity, with focus on technique, outcomes, and complications.</p><p><strong>Case presentation: </strong>A 65-year-old female with Scheuermann's disease developed progressive thoracic hyperkyphosis due to osteoporotic vertebral fractures. Radiographs showed a rigid kyphosis of 130.3°. The patient underwent a two-stage surgery: cement-augmented instrumentation (T2-L3), followed by contiguous PSOs from T6 to T9. Neurophysiological monitoring was used throughout.</p><p><strong>Results: </strong>Kyphosis was corrected from 130.3° to 48°. Postoperatively, the patient developed progressive lower limb weakness due to spinal cord kinking. Revision surgery allowed neurological recovery. At two years, radiological parameters remained stable, and the patient reported reduced pain, improved mobility, and restored quality of life.</p><p><strong>Conclusion: </strong>Four-level PSO can be an effective treatment for severe rigid thoracic hyperkyphosis in osteoporotic patients. Although technically demanding and associated with potential complications, careful planning and staged correction can result in successful outcomes.</p><p><strong>Level of evidence: </strong>IV (Case Report).</p>","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145917351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}