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A review on the immunomodulatory properties of functional nutraceuticals as dietary interventions for children to combat COVID-19 related infections. 功能性营养品作为儿童对抗新冠肺炎相关感染的饮食干预措施的免疫调节特性综述
IF 4 3区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2023-01-01 Epub Date: 2023-04-06 DOI: 10.1186/s43014-023-00133-4
Swati Soni, Kuppusamy Alagesan Paari

COVID-19 is a significant threat to humanity in the present day due to the rapid increase in the number of infections worldwide. While most children may be spared of the direct mortality effects of the disease, those with weak immune systems are prone to adverse effects. Child mortality increases due to the stress caused to the health care system that disrupts essential health care needs such as immunisation and antenatal care. The use of functional foods (FF) aids in disease-prevention as they are known to have protective effects against COVID-19 by boosting children's cellular and humoral immunity. Plant components such as glycyrrhizin, epigallocatechin gallate, allicin, and fucoidan exhibit antiviral properties against various viruses, including SARS-CoV 2. Microbial foods that are made of probiotics, can enhance immunity against various respiratory viruses. Food enriched with additives such as lactoferrin, piperine, and zinc can boost immunity against COVID-19. With proper definitive drug therapy not available for treating COVID-19 and most of the disease management tools rely on symptoms and non-specific supportive care, developing a functional paediatric formulation will prevent further deterioration in infant health. It is wise to investigate the toxicological aspects of Functional Foods components especially when formulating for children. The safe limits of ingredients should be strictly followed during FFs formulation. Stronger regulations with advanced analytical techniques can help to formulate functional foods into the mainstream in child nutraceuticals. The purpose of this review is to compile collective information on the functional nutraceuticals specifically for infants and children up to the age of 10 years that could confer immunity against COVID-19 and other related viruses.

Graphical abstract:

由于全球感染人数迅速增加,COVID-19目前对人类构成重大威胁。虽然大多数儿童可能免于这种疾病的直接死亡影响,但免疫系统较弱的儿童容易受到不利影响。由于对卫生保健系统造成压力,破坏了免疫接种和产前保健等基本卫生保健需求,儿童死亡率上升。使用功能食品有助于预防疾病,因为已知功能食品通过增强儿童的细胞和体液免疫力,对COVID-19具有保护作用。植物成分如甘草酸、表没食子儿茶素没食子酸酯、大蒜素和褐藻糖聚糖对各种病毒(包括SARS-CoV 2)具有抗病毒特性。由益生菌制成的微生物食品可以增强对各种呼吸道病毒的免疫力。富含乳铁蛋白、胡椒碱和锌等添加剂的食物可以增强对COVID-19的免疫力。由于无法获得治疗COVID-19的适当决定性药物治疗,而且大多数疾病管理工具依赖于症状和非特异性支持性护理,因此开发一种功能性儿科配方将防止婴儿健康进一步恶化。调查功能性食品成分的毒理学方面是明智的,特别是当为儿童配制时。在ff的配制过程中,应严格遵守成分的安全限量。更强有力的法规和先进的分析技术可以帮助制定功能食品成为儿童营养保健品的主流。本综述的目的是汇编专门针对婴儿和10岁以下儿童的功能性营养保健品的集体信息,这些功能性营养保健品可以赋予婴儿和10岁以下儿童对COVID-19和其他相关病毒的免疫力。图形化的简介:
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引用次数: 0
Phytochemical constitution and antioxidant activity of functional herbal drink from Indian gooseberry (Emblica officinalis Gaertn.) fruits containing spices and condiments. 含香料和调味品的印度醋栗(Emblica officinalis Gaertn.)功能性草药饮料的植物化学成分和抗氧化活性
IF 4 3区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2023-01-01 Epub Date: 2023-06-01 DOI: 10.1186/s43014-022-00127-8
Saji Gomez, C Anjali, Bintu Kuruvila, P K Maneesha, Meagle Joseph

Functional beverages originate primarily from fruits and vegetables sources, but also include those from other plants such as tea, coffee, cocoa, soybean as well as animal products like milk and dairy-based and alcoholic drinks. They have definite medical or health benefits which include prevention or delaying the progress of diseases. Indian gooseberry is a very rich source of vitamin C and phenolics, two potent antioxidant compounds. Similarly curcumin in turmeric, piperine in black pepper and gingerol in ginger have proven antioxidant and anti-inflammatory properties. Incidence of covid-19 pandemic has raised awareness among people the importance of maintaining higher levels of immunity. A study was undertaken at Kerala Agricultural University during 2020-21 to develop an herbal functional drink from Indian gooseberry fruit juice incorporated with turmeric and black pepper powders, ginger juice extract and juice of acid lime fruits. The herbal drink formulated with these ingredients was homogenized at an operating pressure of 175 Bar with a speed of 235 SPM and was subsequently pasteurized at 100 0 C for 10 minutes in glass bottles, followed by storage under refrigerated conditions at 5 ± 2 0 C for 3 months. The initial ascorbic acid, total phenolics, total flavonoids, total carotenoids and total curcumin contents were 61.0 mg100g- 1, 184.0 mg100g- 1, 153.0 mg100g- 1, 119.98 mg100g- 1 and 31.0 mg100g- 1, respectively. Antioxidant activity of the herbal drink was determined by three assays, viz. ABTS, DDPH and FRAP. The initial IC 50 values of the herbal drink by ABTS, DPPH and FRAP assays were 8.64, 0.212 and 0.368 μgml- 1, respectively. Significant decline in ascorbic acid, total flavonoids, total carotenoids and curcumin content were recorded in the product during storage in contrast to the total phenolics content which showed a significant rise over the storage period. Antioxidant activity of the herbal drink determined by all the three assays also declined significantly throughout the storage period. The results indicate that the product can be promoted as a healthy drink which has to be stored at low temperature in order to retain higher levels of antioxidant compounds and antioxidant activity.

Graphical abstract:

功能性饮料主要来源于水果和蔬菜,但也包括来自其他植物的饮料,如茶、咖啡、可可、大豆以及动物产品,如牛奶、乳制品和酒精饮料。它们具有明确的医疗或健康益处,包括预防或延缓疾病的进展。印度醋栗富含维生素C和酚类物质,这是两种有效的抗氧化化合物。同样,姜黄中的姜黄素、黑胡椒中的胡椒碱和生姜中的姜辣素也被证明具有抗氧化和抗炎的特性。2019冠状病毒病大流行的发生率提高了人们对保持较高免疫力重要性的认识。2020- 2021年期间,喀拉拉邦农业大学进行了一项研究,以印度醋栗果汁为原料,加入姜黄和黑胡椒粉、姜汁提取物和酸橙果汁,开发出一种草药功能饮料。用这些成分配制的草药饮料在175 Bar的操作压力下以235 SPM的速度均质,随后在100℃的玻璃瓶中巴氏消毒10分钟,然后在5±20℃的冷藏条件下储存3个月。初始抗坏血酸、总酚类、总黄酮、总类胡萝卜素和总姜黄素含量分别为61.0 mg100g- 1、184.0 mg100g- 1、153.0 mg100g- 1、119.98 mg100g- 1和31.0 mg100g- 1。采用ABTS、DDPH和FRAP三种检测方法测定该草药饮料的抗氧化活性。ABTS、DPPH和FRAP测定的初始IC 50值分别为8.64、0.212和0.368 μgml- 1。贮藏期间,产品中抗坏血酸、总黄酮、类胡萝卜素和姜黄素含量显著下降,而总酚类含量则显著上升。三种方法测定的草药饮料的抗氧化活性在贮藏期间也显著下降。结果表明,为了保持较高水平的抗氧化化合物和抗氧化活性,该产品可以作为一种健康饮料进行推广。图形化的简介:
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引用次数: 0
A review on biochemical constituents of pumpkin and their role as pharma foods; a key strategy to improve health in post COVID 19 period. 综述了南瓜的生物化学成分及其作为药用食品的作用;在2019冠状病毒病后时期改善健康的关键策略
IF 4 3区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2023-01-01 Epub Date: 2023-03-22 DOI: 10.1186/s43014-023-00138-z
Ashiq Hussain, Tusneem Kausar, Sawera Sehar, Ayesha Sarwar, Muhammad Yousaf Quddoos, Jawed Aslam, Atif Liaqat, Tahira Siddique, Qurat Ul An, Samina Kauser, Abdul Rehman, Rizwan Nisar

Progression of today's world has been given setback due to the adversity of a novel, viral, deadly outbreak COVID 19, which raised the concerns of the scientists, researchers and health related officials about the inherent and adaptive immune system of the living body and its relation with healthy diet balanced with pharma foods. Now world is coming out of the destructive pandemic era, the choice of right food can help to build and boost adaptive immunity and pumpkin due to excellent profile of functional and nutraceutical constituents could be the part of both infected and non-infected person's daily diet. Vitamins like A, C and E, minerals like zinc, iron and selenium, essential oils, peptides, carotenoids and polysaccharides present in pumpkin could accommodate the prevailing deficiencies in the body to fought against the viral pathogens. In current post COVID 19 scenario adequate supply of healthy diet, balanced with pharma foods could play a basic role in boosting immune system of the populations. This review covers the pharmacological activities of pumpkin functional constituents in relation with COVID 19 pandemic. Pumpkins are well equipped with nutraceuticals and functional bioactives like tocopherols, polyphenols, terpenoids and lutein therefore, consumption and processing of this remarkable vegetable could be encouraged as pharma food due to its antihyperlipidemic, antiviral, anti-inflammatory, antihyperglycemic, immunomodulatory, antihypertensive, antimicrobial and antioxidant potential. Need of healthy eating in current post COVID 19 period is very crucial for healthy population, and medicinal foods like pumpkin could play a vital role in developing a healthy community around the globe.

Graphical abstract:

由于新型病毒性致命疫情COVID - 19的逆境,当今世界的进步受到挫折,这引起了科学家,研究人员和卫生相关官员对生物固有和适应性免疫系统及其与健康饮食平衡的关系的担忧。现在世界正在走出毁灭性的大流行时代,选择正确的食物可以帮助建立和增强适应性免疫,南瓜由于其出色的功能和营养成分,可以成为感染者和非感染者日常饮食的一部分。南瓜中的维生素如A、C和E,矿物质如锌、铁和硒,精油,多肽,类胡萝卜素和多糖可以弥补体内普遍存在的缺陷,以对抗病毒病原体。在COVID - 19后的当前情况下,充足的健康饮食供应,与制药食品相平衡,可以在增强人群免疫系统方面发挥基本作用。本文综述了南瓜功能成分与COVID - 19大流行相关的药理活性。南瓜富含营养药品和功能性生物活性物质,如生育酚、多酚、萜类和叶黄素,因此,由于其抗高血脂、抗病毒、抗炎、降血糖、免疫调节、降压、抗菌和抗氧化的潜力,这种非凡的蔬菜的消费和加工可以被鼓励作为制药食品。新冠肺炎疫情后,健康饮食需求对健康人群至关重要,南瓜等药用食品可以在全球健康社区建设中发挥重要作用。图形化的简介:
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引用次数: 0
An overview on the nutritional and bioactive components of green seaweeds. 绿色海藻的营养和生物活性成分综述
IF 4 3区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2023-01-01 Epub Date: 2023-03-20 DOI: 10.1186/s43014-023-00132-5
Jingxiang Xu, Wei Liao, Yuning Liu, Yuling Guo, Shiyue Jiang, Chao Zhao

Green seaweed, as the most abundant species of macroseaweeds, is an important marine biological resource. It is a rich source of several amino acids, fatty acids, and dietary fibers, as well as polysaccharides, polyphenols, pigments, and other active substances, which have crucial roles in various biological processes such as antioxidant activity, immunoregulation, and anti-inflammatory response. In recent years, attention to marine resources has accelerated the exploration and utilization of green seaweeds for greater economic value. This paper elaborates on the main nutrients and active substances present in different green seaweeds and provides a review of their biological activities and their applications for high-value utilization.

Graphical abstract:

绿海藻是大型海藻中数量最多的一种,是重要的海洋生物资源。它是多种氨基酸、脂肪酸、膳食纤维以及多糖、多酚、色素和其他活性物质的丰富来源,这些活性物质在各种生物过程中起着至关重要的作用,如抗氧化活性、免疫调节和抗炎反应。近年来,人们对海洋资源的重视加快了对绿色海藻的开发利用,以期获得更大的经济价值。本文阐述了不同绿海藻中存在的主要营养物质和活性物质,并对其生物活性及其在高价值利用方面的应用进行了综述。图形化的简介:
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引用次数: 0
Impact of drying on the bioactive compounds and antioxidant properties of bignay [Antidesma bunius (L.) Spreng.] pomace. 干燥对bignay[Antidesma bunius(L.)Spreng.]果渣生物活性化合物和抗氧化性能的影响
IF 4 3区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2023-01-01 Epub Date: 2023-02-07 DOI: 10.1186/s43014-022-00122-z
Claire S Zubia, Gilda Melanie O Babaran, Sheba Mae M Duque, Lotis E Mopera, Lloyd Earl L Flandez, Katherine Ann T Castillo-Israel, Florencio C Reginio

Bignay pomace is a processing byproduct that can be a source of bioactive compounds. However, a suitable dehydration method should be considered to efficiently valorize this waste material into high-value food ingredient and maximize its health-promoting properties. Bignay pomace was subjected to convection oven-drying and freeze-drying to investigate the effect of these pre-processing techniques on the physicochemical, bioactives, and antioxidant properties of the samples. Both drying methods significantly (p<0.05) changed the total phenolic and anthocyanin contents of bignay pomace while flavonoids and tannins were not significantly affected. Freeze-drying of samples resulted in higher phenolic content (1742 vs. 1273 mg gallic acid equivalent/100 g DW) and anthocyanin content (496 vs. 223 mg cyanidin-3-glucoside equivalent/100 g DW) than convection oven-drying. Freeze-drying also resulted in higher antioxidant properties based on DPPH, ABTS radical scavenging activity, and FRAP assays. B ignay pomace extract was analyzed through HPLC (with photo-diode array detector) for its phenolic profile and nine compounds were identified, with catechin and epicatechin as the dominant components. HPLC analysis also showed that while the drying process does not influence the phenolic profile of the samples, it significantly affected the concentration of phenolic compounds present. The results of this study showed that freeze-drying is a more viable method to retain the majority of bignay pomace's functional properties compared to convection oven-drying.

Graphical abstract:

豆渣是加工过程的副产品,可能是生物活性化合物的来源。然而,应该考虑一种合适的脱水方法,以有效地将这种废物转化为高价值的食品原料,并最大限度地发挥其促进健康的作用。采用对流干燥法和冷冻干燥法研究了不同预处理技术对Bignay渣的理化、生物活性和抗氧化性能的影响。两种干燥方法对果渣的黄酮和单宁含量影响不显著。冷冻干燥样品的酚含量(1742比1273毫克没食子酸当量/100克DW)和花青素含量(496比223毫克花青素-3-葡萄糖苷当量/100克DW)高于对流干燥。根据DPPH、ABTS自由基清除活性和FRAP测定,冷冻干燥也导致了更高的抗氧化性能。采用高效液相色谱法(光电二极管阵列检测器)对木犀草渣提取物的酚类成分进行分析,鉴定出以儿茶素和表儿茶素为主要成分的9个化合物。HPLC分析还表明,虽然干燥过程不影响样品的酚类成分,但会显著影响样品中酚类化合物的浓度。本研究结果表明,与对流干燥相比,冷冻干燥是一种更可行的方法,可以保留大部分大豆渣的功能特性。图形化的简介:
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引用次数: 0
Nutritional, health benefits and toxicity of underutilized garden cress seeds and its functional food products: a review 未充分利用的花园水芹种子及其功能性食品的营养、健康益处和毒性:综述
IF 4.7 3区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2022-12-01 DOI: 10.1186/s43014-022-00114-z
Meseret Azene, Kifle Habte, Helen Tkuwab
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引用次数: 3
Immobilization of Lactobacillus plantarum NCIMB 8826 ameliorates Citrobacter rodentium induced lesions and enhances the gut inflammatory response in C57BL/6 weanling mice 植物乳杆菌NCIMB 8826的固定化改善C57BL/6断奶小鼠的柠檬酸杆菌诱导的损伤并增强肠道炎症反应
IF 4.7 3区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2022-12-01 DOI: 10.1186/s43014-022-00111-2
E. Kyereh, Diana B Coulon, I. Langohr, Anne M. Raggio, Michael Keenan, S. Sathivel
{"title":"Immobilization of Lactobacillus plantarum NCIMB 8826 ameliorates Citrobacter rodentium induced lesions and enhances the gut inflammatory response in C57BL/6 weanling mice","authors":"E. Kyereh, Diana B Coulon, I. Langohr, Anne M. Raggio, Michael Keenan, S. Sathivel","doi":"10.1186/s43014-022-00111-2","DOIUrl":"https://doi.org/10.1186/s43014-022-00111-2","url":null,"abstract":"","PeriodicalId":12395,"journal":{"name":"Food Production, Processing and Nutrition","volume":" ","pages":"1-12"},"PeriodicalIF":4.7,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49401114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Plant-based pecan nut cake beverage enrichment of phytochemicals and antioxidant properties using multi-stage block freeze concentration 基于植物的山核桃坚果蛋糕饮料利用多级块冷冻浓缩富集植物化学物质和抗氧化性能
IF 4.7 3区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2022-12-01 DOI: 10.1186/s43014-022-00116-x
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引用次数: 2
Variations in the substrate composition and microbial community structure in the anaerobic fermentation process using the green algae Enteromorpha prolifera 利用浒苔厌氧发酵过程中底物组成和微生物群落结构的变化
IF 4.7 3区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2022-11-29 DOI: 10.1186/s43014-022-00110-3
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{"title":"Variations in the substrate composition and microbial community structure in the anaerobic fermentation process using the green algae Enteromorpha prolifera","authors":"Chao Ai, Ai-Jun Tong, Jiahui Wen, Ruoxin Chen, Yajun Huang, Chao Zhao","doi":"10.1186/s43014-022-00110-3","DOIUrl":"https://doi.org/10.1186/s43014-022-00110-3","url":null,"abstract":"","PeriodicalId":12395,"journal":{"name":"Food Production, Processing and Nutrition","volume":"4 1","pages":"1-12"},"PeriodicalIF":4.7,"publicationDate":"2022-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47402021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Optimization of the iron-enriched extruded snack containing jackfruit seed flour, mung bean flour and ferrous ammonium phosphate by using response surface methodology 利用响应面法优化含有菠萝蜜籽粉、绿豆粉和磷酸亚铁的富铁挤压小吃
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引用次数: 1
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Food Production, Processing and Nutrition
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