Global Challenges最新文献

Inhospitable, inaccessible, and extremely remote alike the famed pole of inaccessibility, aka Point Nemo, the isolated locations in deserts, at sea, or in outer space are difficult for humans to settle, let alone to thrive in. Yet, they present a unique set of opportunities for science, economy, and geopolitics that are difficult to ignore. One of the critical challenges for settlers is the stable supply of energy both to sustain a reasonable quality of life, as well as to take advantage of the local opportunities presented by the remote environment, e.g., abundance of a particular resource. The possible solutions to this challenge are heavily constrained by the difficulty and prohibitive cost of transportation to and from such a habitat (e.g., a lunar or Martian base). In this essay, the advantages and possible challenges of integrating Fischer–Tropsch, artificial photosynthesis, and plasma catalysis into a robust, scalable, and efficient self-contained system for energy harvesting, storage, and utilization are explored.

Ninety percent of the large interior, rural part of Africa is not an abundant user of fossil fuels and is not connected to an electricity grid. This limits habitability and leads to significant migration to larger cities in attempts to improve economic and social welfare, which happens at the cost of its rich cultural diversity by inevitable adaption and mixing of societies. A direct transition from a firewood to an off-grid renewable electricity age can mitigate this detrimental development. This perspective discusses the interdisciplinary requirements linking cultural, sociological, economic, and technical aspects for a transition to modern life without loss of valuable traditions. Photovoltaic power and wind energy can provide local affordable electricity in off-grid locations. Intermediate storage for day–night cycles is catered for by novel types of batteries. Purifying and recycling water, refrigerating food and medicine, and benefitting from contact with the world via electronic media permit a tremendous increase in living conditions and significantly lower the pressure of migration into cities. Access to energy is a fundamental requirement for the preservation of the rich cultural diversity with family and tribal bindings, local languages, traditions, and religions, and allows for a more moderate transition to a modern society.

The potential of strawberry-derived protease as a component of laundry detergent is investigated. The compatibility of the enzyme with various surfactants, oxidizing agents, and commercial detergents is tested. The immobilized enzyme prepared by immobilizing Co²⁺ ions together with the enzyme is also tested. Strawberry crude protease shows high stability in the presence of surfactants frequently used in detergents. The enzyme is found to be relatively stable to oxidizing agents. In addition, it is determined that strawberry protease works in excellent compatibility with different commercial solid and liquid detergents in the Turkish market and also maintains its stability very well. Washing tests based on visual examination also reveal that the enzyme improves the washing performance of the tested detergent. All these properties and high activity at alkaline pH make this enzyme a very strong candidate for use in laundry detergent formulations.

High entropy oxides (HEOs) offer great potential as catalysts for oxygen electrocatalytic reactions in alkaline environments. Herein, a novel synthesis approach to prepare (FeCrCoMnZn)₃O_4-δ high entropy spinel oxide in a vacuum atmosphere, with the primary objective of introducing oxygen vacancies into the crystal structure, is presented. As compared to the air-synthesized counterpart, the (FeCrCoMnZn)₃O_4-δ with abundant oxygen vacancies demonstrates a low (better) bifunctional (BI) index of 0.89 V in alkaline media, indicating enhanced electrocatalytic oxygen catalytic activity. Importantly, (FeCrCoMnZn)₃O_4-δ demonstrates outstanding long-term electrochemical and structural stability. When utilized as electrocatalysts in the air cathode of Zn-air batteries, the vacuum atmosphere synthesized (FeCrCoMnZn)₃O_4-δ catalysts outperform the samples treated in an air atmosphere, displaying superior peak power density, specific capacity, and cycling stability. These findings provide compelling evidence that manipulating the synthesis atmosphere of multi-component oxides can serve as a novel approach to tailor their electrochemical performance.

Green hydrogen is the key to the chemical industry achieving net zero emissions. The chemical industry is responsible for almost 2% of all CO₂ emissions, with half of it coming from the production of simple commodity chemicals, such as NH₃, H₂O₂, methanol, and aniline. Despite electrolysis driven by renewable power sources emerging as the most promising way to supply all the green hydrogen required in the production chain of these chemicals, in this review, it is worth noting that the photocatalytic route may be underestimated and can hold a bright future for this topic. In fact, the production of H₂ by photocatalysis still faces important challenges in terms of activity, engineering, and economic feasibility. However, photocatalytic systems can be tailored to directly convert sunlight and water (or other renewable proton sources) directly into chemicals, enabling a solar-to-chemical strategy. Here, a series of recent examples are presented, demonstrating that photocatalysis can be successfully employed to produce the most important commodity chemicals, especially on NH₃, H₂O₂, and chemicals produced by reduction reactions. The replacement of fossil-derived H₂ in the synthesis of these chemicals can be disruptive, essentially safeguarding the transition of the chemical industry to a low-carbon economy.

The explosive growth of biomedical Big Data presents both significant opportunities and challenges in the realm of knowledge discovery and translational applications within precision medicine. Efficient management, analysis, and interpretation of big data can pave the way for groundbreaking advancements in precision medicine. However, the unprecedented strides in the automated collection of large-scale molecular and clinical data have also introduced formidable challenges in terms of data analysis and interpretation, necessitating the development of novel computational approaches. Some potential challenges include the curse of dimensionality, data heterogeneity, missing data, class imbalance, and scalability issues. This overview article focuses on the recent progress and breakthroughs in the application of big data within precision medicine. Key aspects are summarized, including content, data sources, technologies, tools, challenges, and existing gaps. Nine fields—Datawarehouse and data management, electronic medical record, biomedical imaging informatics, Artificial intelligence-aided surgical design and surgery optimization, omics data, health monitoring data, knowledge graph, public health informatics, and security and privacy—are discussed.

This study offers a comprehensive analysis of the distribution, evolution, and driving factors of CO₂ emissions from 1990 to 2016 at multiple spatial scales. Utilizing 26 indicators encompassing various facets of CO₂ emissions, it is employed principal component analysis (PCA) and empirical orthogonal functions (EOFs) to identify the dominant characteristics of global CO₂ emissions. This model retained three core components, accounting for 93% of the global CO₂ variation, reflecting emission trajectories and associated economic metrics, such as Gross domestic product (GDP). The analysis differentiated the effects of these components based on countries' economic standings. Using a novel aggregated index, significant national contributors to global CO₂ emissions are pinpointed. Notably, the leading contributors are found among developed nations (e.g., the United States, Canada, Japan), Gulf states (e.g., Saudi Arabia, Qatar), and emerging economies (e.g., China, Brazil, Mexico). Furthermore, these results highlight that shifts in global CO₂ emissions over the past 30 years are predominantly influenced by factors like industrial emissions and GDP. Results also demonstrate a distinct relationship between a country's CO₂ emissions and its physical and socioeconomic factors. Specifically, the nation's coastline length, population density in coastal regions, and the diversity of its climatic conditions significantly influence its carbon footprint.

Various concentrations of samarium-grafted-carbon nitride (Sm-g-C₃N₄) doped-bismuth oxobromide (BiOBr) quantum dots (QDs) are prepared by the co-precipitation method. Elemental evaluation, morphological, optical, and functional group assessment are studied employing characterization techniques. Based on the XRD pattern analysis, it is determined that BiOBr exhibits a tetragonal crystal structure. The electronic spectroscopy revealed an absorption peak for BiOBr at 315 nm and the bandgap energy (E_g) decreasing from 3.9 to 3.8 eV with the insertion of Sm-g-C₃N₄. The presence of vibrational modes related to BiOBr at 550 cm⁻¹ is confirmed through FTIR spectra. TEM revealed that pure BiOBr possessed non-uniform QDS, and agglomeration increased with the addition of Sm-g-C₃N₄. The catalytic performance of Sm-g-C₃N₄ into BiOBr (6 mL) in a neutral medium toward rhodamine B exhibited excellent results (99.66%). The bactericidal activity is evaluated against multi-drug resistance (MDR) Escherichia coli once the surface area is increased by dopant and the measured inhibition zone is assessed to be 3.65 mm. Molecular docking results supported the in vitro bactericidal potential of Sm-g-C₃N₄ and Sm-g-C₃N₄ doped-BiOBr as DNA gyrase_{E. coli} inhibitors. This study shows that the novel Sm-g-C₃N₄ doped-BiOBr is a better catalyst that increases specific semiconductor's catalytic activity (CA).

Fungi adapt to their surroundings, modifying their behaviors and composition under different conditions like nutrient availability and environmental stress. This perspective examines how a basic understanding of fungal genetics and the different ways that fungi can be influenced by their surroundings can be leveraged toward the production of functional mycelium materials. Simply put, within the constraints of a given genetic script, both the quality and quantity of fungal mycelium are shaped by what they eat and where they grow. These two levers, encompassing their global growth environment, can be turned toward different materials outcomes. The final properties of myco-materials are thus intimately shaped by the conditions of their growth, enabling the design of new biobased and biodegradable material constructions for applications that have traditionally relied on petroleum-based chemicals.This perspective highlights aspects of fungal genetics and environmental adaptation that have potential materials science implications, along the way touching on key studies, both to situate the state of the art within the field and to punctuate the viewpoints of the authors. Finally, this work ends with future perspectives, reinforcing key topics deemed important to consider in emerging myco-materials research.