首页 > 最新文献

International Journal of TROPICAL DISEASE & Health最新文献

英文 中文
Geohelminth Infections and Nutritional Status of Mbororo Children 2 - 15 Years in the Bafmeng Health Area, North West Cameroon 喀麦隆西北部巴夫蒙卫生区2 - 15岁姆博罗罗族儿童地虫感染和营养状况
Pub Date : 2023-06-19 DOI: 10.9734/ijtdh/2023/v44i111437
Ismaila Karimu, R. Nyasa, Tendongfor Nicholas
Background: Geohelminth infections are endemic in Cameroon affecting millions of people and have serious nutritional and developmental effects especially among children. Aims: There is paucity of information on the prevalence, risk factors and nutritional effect of geohelminths on minority nomadic Mbororo communities in Cameroon, which is addressed herein amongst children 2-15 years in the Bafmeng Health Area. Materials and Methods: A cross-sectional community based study was conducted between April 2021 and June 2021 in which 263 children, within the age 2-15 years were randomly recruited and a structured questionnaire was administered to them and their caregivers to obtain socio-demographic data, hygienic practices and knowledge of caregivers regarding geohelminth infections. A single-stool sample was obtained from each child and analyzed using the Kato-Katz technique and anthropometric measurements were also obtained and used to compute nutritional indices using the World Health Organization Anthro software. Bivariate and multivariate logistic regression were used to identify risk factors of geohelminth infections. Results: The prevalence of geohelminth infections was 14.4% (38); Ascaris lumbricoides (11.41%), Trichuris trichuira (2.7%), and hook worm (0.4%). A total of 61.2% (161) of the children were malnourished; underweight (28.5%), stunting (19.0%), severe stunting (11.0%), severely underweight (1.9%), and wasting (0.8%). Geohelminth infection was not associated with nutritional status (P=0.4) but it was significantly (p=0.004) associated with males (21.9%) than females (8.7%). The use of unsafe water (P=0.03, AOR: 2.01, CI: 1.04 - 1.77) and dumping of waste around the compound (P=0.01, AOR=1.35, CI: 0.13 – 0.95) were risk factors significantly associated with geohelminth infection. Majority of the caregivers (75.3%) had good knowledge on the transmission and prevention of geohelminths. Conclusion: On a whole, the prevalence of geohelminth infection is low and malnutrition is high amongst Mbororo children. Long-term control strategies should focus on improvements on environmental hygiene, provision of portable water along side nutritional interventions.
背景:地蚯蚓感染在喀麦隆流行,影响数百万人,并对营养和发育产生严重影响,特别是对儿童。目的:关于地虫对喀麦隆游牧民族姆博罗罗人社区的流行程度、风险因素和营养影响的信息缺乏,本文针对巴富蒙保健区2-15岁儿童的情况。材料和方法:在2021年4月至2021年6月期间进行了一项基于社区的横断面研究,随机招募了263名年龄在2-15岁之间的儿童,并对他们及其照顾者进行了结构化问卷调查,以获取社会人口统计数据、卫生习惯和照顾者关于地虫感染的知识。从每个儿童身上获得一份粪便样本,并使用Kato-Katz技术进行分析,还获得人体测量数据,并使用世界卫生组织人类软件计算营养指数。采用双变量和多变量logistic回归来确定地蚓感染的危险因素。结果:地虫病感染率为14.4%(38例);类蚓蛔虫(11.41%)、trichuira(2.7%)、hook worm(0.4%)。61.2%(161)儿童营养不良;体重不足(28.5%)、发育迟缓(19.0%)、严重发育迟缓(11.0%)、严重体重不足(1.9%)和消瘦(0.8%)。地虫病感染与营养状况无相关性(P=0.4),但与男性(21.9%)的相关性显著(P= 0.004)高于女性(8.7%)。使用不安全水(P=0.03, AOR: 2.01, CI: 1.04 ~ 1.77)和小区周边倾倒废弃物(P=0.01, AOR=1.35, CI: 0.13 ~ 0.95)是地虫病感染的危险因素。大多数护理人员(75.3%)对地虫的传播和预防有较好的认识。结论:从总体上看,姆博罗罗族儿童地虫感染率较低,营养不良发生率较高。长期控制战略应侧重于改善环境卫生、提供便携水以及营养干预措施。
{"title":"Geohelminth Infections and Nutritional Status of Mbororo Children 2 - 15 Years in the Bafmeng Health Area, North West Cameroon","authors":"Ismaila Karimu, R. Nyasa, Tendongfor Nicholas","doi":"10.9734/ijtdh/2023/v44i111437","DOIUrl":"https://doi.org/10.9734/ijtdh/2023/v44i111437","url":null,"abstract":"Background: Geohelminth infections are endemic in Cameroon affecting millions of people and have serious nutritional and developmental effects especially among children. \u0000Aims: There is paucity of information on the prevalence, risk factors and nutritional effect of geohelminths on minority nomadic Mbororo communities in Cameroon, which is addressed herein amongst children 2-15 years in the Bafmeng Health Area. \u0000Materials and Methods: A cross-sectional community based study was conducted between April 2021 and June 2021 in which 263 children, within the age 2-15 years were randomly recruited and a structured questionnaire was administered to them and their caregivers to obtain socio-demographic data, hygienic practices and knowledge of caregivers regarding geohelminth infections. A single-stool sample was obtained from each child and analyzed using the Kato-Katz technique and anthropometric measurements were also obtained and used to compute nutritional indices using the World Health Organization Anthro software. Bivariate and multivariate logistic regression were used to identify risk factors of geohelminth infections. \u0000Results: The prevalence of geohelminth infections was 14.4% (38); Ascaris lumbricoides (11.41%), Trichuris trichuira (2.7%), and hook worm (0.4%). A total of 61.2% (161) of the children were malnourished; underweight (28.5%), stunting (19.0%), severe stunting (11.0%), severely underweight (1.9%), and wasting (0.8%). Geohelminth infection was not associated with nutritional status (P=0.4) but it was significantly (p=0.004) associated with males (21.9%) than females (8.7%). The use of unsafe water (P=0.03, AOR: 2.01, CI: 1.04 - 1.77) and dumping of waste around the compound (P=0.01, AOR=1.35, CI: 0.13 – 0.95) were risk factors significantly associated with geohelminth infection. Majority of the caregivers (75.3%) had good knowledge on the transmission and prevention of geohelminths. \u0000Conclusion: On a whole, the prevalence of geohelminth infection is low and malnutrition is high amongst Mbororo children. Long-term control strategies should focus on improvements on environmental hygiene, provision of portable water along side nutritional interventions.","PeriodicalId":126794,"journal":{"name":"International Journal of TROPICAL DISEASE & Health","volume":"153 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129152649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neonatal Iron Stores Depend on Gestational Age: A Prospective Comparative Cross-sectional Study at Neonatal Intensive Care Unit, University of Nigeria Teaching Hospital, Enugu State, Nigeria 新生儿铁储量依赖于胎龄:尼日利亚埃努古州尼日利亚大学教学医院新生儿重症监护病房的前瞻性比较横断面研究
Pub Date : 2023-06-10 DOI: 10.9734/ijtdh/2023/v44i101436
I. Asinobi
Aims: To establish mean values for serum ferritin at different gestational ages. To determine the relationship between serum ferritin and gestational age. Methodology: This was a prospective, comparative, cross sectional study carried out at the Neonatal Intensive Care Unit of the University of Nigeria Teaching Hospital (UNTH), Enugu State, Nigeria between June and December 2014. The study included 140 newborns with gestational ages of 25 weeks to 39 weeks, delivered at the UNTH. Babies with C-reactive protein levels > 10mg/dl, who were intra-uterine growth restricted, and whose mothers had conditions associated with low iron stores were excluded from the study. Anthropometric measurements were recorded for all subjects. Serum ferritin was measured at birth and this was correlated with gestational age. Results: Serum ferritin levels ranged from 20.6 to 296.4µg/l. The mean serum ferritin level was 93.14µg/l ± 57.69. There was a significant difference among the mean serum ferritin levels amongst different categories of gestational age (F = 11.159, P <.001).  Low serum ferritin was found in 85.7%, 48.1% and 16.7% of extreme preterms, very preterms and moderate to late preterms respectively 2 = 49.777, P < .05). Extreme preterms were sixty-four times more likely than term babies to have low serum ferritin (P <.01, OR = 64.00, 95% C.I for OR = 6.570 – 623.455), while very preterms were ten times more likely than term babies to have low serum ferritin levels (P < .001, OR = 9.905 95% C.I = 3.209 -30.570). In addition, moderate to late preterms were two times more likely than term babies to have low serum ferritin levels (P = 0.220, OR = 2.133, 95% C.I for OR = 0.635 – 7.167). There was a significant strong positive correlation between serum ferritin levels and gestational age in the study population (r = 0.656, P < .001). Conclusion: There is a wide range of serum ferritin amongst newborn babies. There is also a significant strong positive correlation between serum ferritin levels and gestational age.
目的:建立不同胎龄血清铁蛋白的平均值。目的:探讨血清铁蛋白与胎龄的关系。方法:这是一项前瞻性、对比性、横断面研究,于2014年6月至12月在尼日利亚埃努古州尼日利亚大学教学医院(UNTH)新生儿重症监护室进行。这项研究包括140名胎龄在25周到39周的新生儿,他们都是在UNTH出生的。c反应蛋白水平> 10mg/dl的婴儿,子宫内生长受限,其母亲患有与低铁储存相关的疾病,被排除在研究之外。记录所有受试者的人体测量值。在出生时测定血清铁蛋白,这与胎龄有关。结果:血清铁蛋白水平为20.6 ~ 296.4µg/l。血清铁蛋白平均水平为93.14µg/l±57.69。不同胎龄组血清铁蛋白水平差异有统计学意义(F = 11.159, P < 0.001)。重度早产、重度早产和中晚期早产患者血清铁蛋白水平分别为85.7%、48.1%和16.7% (2 = 49.777,P < 0.05)。极端早产儿血清铁蛋白水平低的可能性是足月婴儿的64倍(P < 0.05)。0.01, OR = 64.00, 95% ci = 6.570 - 623.455),而极早产儿血清铁蛋白水平低的可能性是足月婴儿的10倍(P < 0.001, OR = 9.905 95% ci = 3.209 -30.570)。此外,中度至晚期早产儿血清铁蛋白水平低的可能性是足月婴儿的两倍(P = 0.220, OR = 2.133, 95% ci = 0.635 - 7.167)。研究人群血清铁蛋白水平与胎龄呈正相关(r = 0.656, P < 0.001)。结论:新生儿血清铁蛋白水平变化范围广。血清铁蛋白水平与胎龄之间也存在显著的强正相关。
{"title":"Neonatal Iron Stores Depend on Gestational Age: A Prospective Comparative Cross-sectional Study at Neonatal Intensive Care Unit, University of Nigeria Teaching Hospital, Enugu State, Nigeria","authors":"I. Asinobi","doi":"10.9734/ijtdh/2023/v44i101436","DOIUrl":"https://doi.org/10.9734/ijtdh/2023/v44i101436","url":null,"abstract":"Aims: To establish mean values for serum ferritin at different gestational ages. To determine the relationship between serum ferritin and gestational age. \u0000Methodology: This was a prospective, comparative, cross sectional study carried out at the Neonatal Intensive Care Unit of the University of Nigeria Teaching Hospital (UNTH), Enugu State, Nigeria between June and December 2014. The study included 140 newborns with gestational ages of 25 weeks to 39 weeks, delivered at the UNTH. Babies with C-reactive protein levels > 10mg/dl, who were intra-uterine growth restricted, and whose mothers had conditions associated with low iron stores were excluded from the study. Anthropometric measurements were recorded for all subjects. Serum ferritin was measured at birth and this was correlated with gestational age. \u0000Results: Serum ferritin levels ranged from 20.6 to 296.4µg/l. The mean serum ferritin level was 93.14µg/l ± 57.69. There was a significant difference among the mean serum ferritin levels amongst different categories of gestational age (F = 11.159, P <.001).  Low serum ferritin was found in 85.7%, 48.1% and 16.7% of extreme preterms, very preterms and moderate to late preterms respectively 2 = 49.777, P < .05). Extreme preterms were sixty-four times more likely than term babies to have low serum ferritin (P <.01, OR = 64.00, 95% C.I for OR = 6.570 – 623.455), while very preterms were ten times more likely than term babies to have low serum ferritin levels (P < .001, OR = 9.905 95% C.I = 3.209 -30.570). In addition, moderate to late preterms were two times more likely than term babies to have low serum ferritin levels (P = 0.220, OR = 2.133, 95% C.I for OR = 0.635 – 7.167). There was a significant strong positive correlation between serum ferritin levels and gestational age in the study population (r = 0.656, P < .001). \u0000Conclusion: There is a wide range of serum ferritin amongst newborn babies. There is also a significant strong positive correlation between serum ferritin levels and gestational age.","PeriodicalId":126794,"journal":{"name":"International Journal of TROPICAL DISEASE &amp; Health","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114417954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Unpreparedness of a Health District in the Face of an Epidemic, the Case of COVID-19 and Its Impact on Neurosurgery Activities 卫生区面对疫情的准备不足、COVID-19病例及其对神经外科活动的影响
Pub Date : 2023-06-10 DOI: 10.9734/ijtdh/2023/v44i101435
J. Fondop, M. C. A. E. Tchoffo, T. Atemken, C. Djam, J. F. O. Ondo, L. T. Takoudjou
In December 2019, the occurrence of several cases of pneumonia of unknown origin in Hubei province in China led to the identification in January 2020 of a new coronavirus, named SARS-CoV-2 by the Coronavirus Working Group of the International Committee on Taxonomy of Viruses.  In 2019 the national strategy to combat COVI 19 planned for national and regional centres.  Thus, as of 20 March 2019, the first suspected cases were registered and taken care of by the District Hospital of Dschang in an unpredictable manner and without any fund. The objective of this study was to describe the management of the COVID 19 epidemic by a district hospital without preparation and to describe its impact on hospital activities, in particular neurosurgery. Methodology: it was a retrospective descriptive study, focused on the documents and the management of human resources, material, suspect patients and financial means of the hospital during the first phase of the epidemic from March - August 2019 the crisis. It wasonly in September 2019 that the plan provided for the monitoring of patients at home and the patient at the case infected in KOUEKONG in Bafoussam in the region. The result A service was created with new staff as a matter of urgency and the hospitalisation of the first suspect led to a drop in the early attendance of the structure, hospitalisation of the hospital  and especially of the surgery service. The barrier measures introduced at the hospital were financed entirely by the hospital's own funds and donations, without any special funding, the hospital's revenue fell from 46,909,106 CFA francs in January 2019 to 27,103,235 CFA francs in June 2019, with a 43% drop in June 2019. expenses, masked by donations, fell from 46,909,106 CFA francs in January 2020 to 24,765,492 CFA francs in May 2020, but increased slightly to reach 38,724,361 CFA francs in August 2020. All activities were affected particularly surgery and neurosurgery. Conclusion: The unpredictable management of the Covi19 epidemic led to a disruption of the hospital's organisation and human resources, a drop in the hospital's income and an increase in the burden of self-management, without subsidies from the hierarchy.
2019年12月,中国湖北省发生了多例来源不明的肺炎病例,导致国际病毒分类委员会冠状病毒工作组于2020年1月确定了一种新的冠状病毒,命名为SARS-CoV-2。2019年,为国家和区域中心制定了抗击covid - 19的国家战略。因此,截至2019年3月20日,第一批疑似病例以不可预测的方式在没有任何资金的情况下由昌区医院登记和治疗。本研究的目的是描述一家地区医院在没有准备的情况下对COVID - 19流行病的管理,并描述其对医院活动,特别是神经外科的影响。方法:这是一项回顾性描述性研究,重点关注2019年3月至8月危机期间流行病第一阶段期间医院的文件和人力资源、物资、疑似患者和财务手段的管理。直到2019年9月,该计划才规定对该地区巴富萨姆的KOUEKONG感染病例的患者和家中患者进行监测。结果,作为紧急事项,设立了一个新工作人员的服务部门,第一个嫌疑人的住院导致该机构的早期出勤率下降,医院住院率下降,特别是手术服务的住院率下降。医院采取的隔离措施完全由医院自己的资金和捐赠资助,没有任何特殊资金,医院的收入从2019年1月的46,909,106非洲法郎下降到2019年6月的27,103,235非洲法郎,2019年6月下降了43%。被捐款掩盖的费用从2020年1月的46,909,106非洲法郎下降到2020年5月的24,765,492非洲法郎,但在2020年8月略有增加,达到38,724,361非洲法郎。所有活动都受到影响,尤其是外科和神经外科。结论:新冠肺炎疫情管理的不可预测性导致医院组织和人力资源中断,医院收入下降,自我管理负担增加,没有层级补贴。
{"title":"The Unpreparedness of a Health District in the Face of an Epidemic, the Case of COVID-19 and Its Impact on Neurosurgery Activities","authors":"J. Fondop, M. C. A. E. Tchoffo, T. Atemken, C. Djam, J. F. O. Ondo, L. T. Takoudjou","doi":"10.9734/ijtdh/2023/v44i101435","DOIUrl":"https://doi.org/10.9734/ijtdh/2023/v44i101435","url":null,"abstract":"In December 2019, the occurrence of several cases of pneumonia of unknown origin in Hubei province in China led to the identification in January 2020 of a new coronavirus, named SARS-CoV-2 by the Coronavirus Working Group of the International Committee on Taxonomy of Viruses.  In 2019 the national strategy to combat COVI 19 planned for national and regional centres.  Thus, as of 20 March 2019, the first suspected cases were registered and taken care of by the District Hospital of Dschang in an unpredictable manner and without any fund. \u0000The objective of this study was to describe the management of the COVID 19 epidemic by a district hospital without preparation and to describe its impact on hospital activities, in particular neurosurgery. \u0000Methodology: it was a retrospective descriptive study, focused on the documents and the management of human resources, material, suspect patients and financial means of the hospital during the first phase of the epidemic from March - August 2019 the crisis. It wasonly in September 2019 that the plan provided for the monitoring of patients at home and the patient at the case infected in KOUEKONG in Bafoussam in the region. \u0000The result A service was created with new staff as a matter of urgency and the hospitalisation of the first suspect led to a drop in the early attendance of the structure, hospitalisation of the hospital  and especially of the surgery service. The barrier measures introduced at the hospital were financed entirely by the hospital's own funds and donations, without any special funding, the hospital's revenue fell from 46,909,106 CFA francs in January 2019 to 27,103,235 CFA francs in June 2019, with a 43% drop in June 2019. expenses, masked by donations, fell from 46,909,106 CFA francs in January 2020 to 24,765,492 CFA francs in May 2020, but increased slightly to reach 38,724,361 CFA francs in August 2020. All activities were affected particularly surgery and neurosurgery. \u0000Conclusion: The unpredictable management of the Covi19 epidemic led to a disruption of the hospital's organisation and human resources, a drop in the hospital's income and an increase in the burden of self-management, without subsidies from the hierarchy.","PeriodicalId":126794,"journal":{"name":"International Journal of TROPICAL DISEASE &amp; Health","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127110881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lessons Learnt from the Management of Severe COVID-19 Disease in a 93-year-old with Chronic Co-Morbidities at a Resource-constrained Centre in Nigeria – A Retrospective Single Case Study 尼日利亚一个资源有限的中心对一名患有慢性合并症的93岁老人的COVID-19重症管理的经验教训——回顾性单一病例研究
Pub Date : 2023-06-07 DOI: 10.9734/ijtdh/2023/v44i101434
C. B. Nwatu, O. Anyim, U. Unigwe
Introduction: Severe COVID-19 infection is associated with significant mortality in the elderly. This is even more so, when the elderly patient with the disease also has multiple chronic co-morbidities, and is resident in a resource-constrained area. Aims/ Objectives: To outline management strategies employed, and important lessons learnt from the successful management of a case of severe COVID-19 disease in a 93-year-old with chronic co-morbidities in a resource-limited setting. Methods: We utilized a simple COVID-19 severity categorization algorithm on presentation, to assign the index patient to the appropriate COVID-19 disease severity class and subsequently employed patient’s serial, weekly clinical and laboratory parameters to guide a multi-specialty management protocol. Results: A 93-year-old man was referred to a tertiary hospital in Enugu during the second wave of the COVID-19 pandemic, with a 5-day-history of high grade fever, severe fatigue, and altered sensorium. He had been living with diabetes for 48years; recently had worsening glycemic control, and was yet to pass urine in the previous 12hours. He was also being managed conservatively for prostate carcinoma. Examination revealed signs of severe pneumonia and he was drowsy, dehydrated, and had asterixis. A diagnosis of acute kidney injury from septicemia, following community acquired pneumonia and possibly urinary tract infection was made, with COVID-19 infection as a differential. Samples were collected for laboratory investigations while he was recommended for intensive care unit admission for further care. Para-enteral broad spectrum antibiotics, intravenous fluid therapy, intranasal oxygen therapy, basal-bolus-insulin-regimen, and anti-coagulation prophylaxis were instituted. Following laboratory investigation results which included a positive COVID-19 test (clinically categorized as severe disease), severe systemic inflammation, evidence of uro-tract infection, intravascular thrombosis and severe renal impairment, the Nephrology, Infectious disease, Urology teams were invited to co-manage the patient alongside the Endocrinologists. After 27days of collaborative care, patient was discharged with resolution of his symptoms and signs. Conclusion: Multi-specialty collaborative care improves patients’ outcome even in the face of severe COVID-19 with associated co-morbidities in elderly patients. Severity stratification ensures life-saving timely care for severe COVID-19 disease.
在老年人中,严重的COVID-19感染与显著的死亡率相关。当老年患者同时患有多种慢性合并症,且居住在资源有限的地区时,情况更是如此。目的/目的:概述所采用的管理策略,以及在资源有限的情况下成功管理一例93岁慢性合并症重症COVID-19病例的重要经验教训。方法:采用简单的COVID-19疾病严重程度分类算法,将指标患者分配到相应的COVID-19疾病严重程度类别,然后利用患者的连续、每周临床和实验室参数指导多专科管理方案。结果:一名93岁男性患者在第二波COVID-19大流行期间转诊至埃努古一家三级医院,有5天的高热、严重疲劳和感觉改变史。他患有糖尿病已经48年了;近期血糖控制恶化,12小时内未排尿。他还因前列腺癌接受了保守治疗。检查显示有严重肺炎的迹象,他嗜睡,脱水,并有星形肿。诊断为败血症引起的急性肾损伤,随后是社区获得性肺炎和可能的尿路感染,以COVID-19感染作为鉴别诊断。收集样本进行实验室调查,同时建议他进入重症监护病房接受进一步治疗。建立了肠外广谱抗生素、静脉输液、鼻内氧疗、基础胰岛素方案和抗凝预防。根据实验室调查结果,包括COVID-19检测阳性(临床归类为严重疾病)、严重全系统炎症、尿路感染、血管内血栓形成和严重肾功能损害的证据,肾脏科、传染病科、泌尿科团队被邀请与内分泌科医生共同管理患者。经过27天的共同护理,患者在症状和体征得到缓解后出院。结论:多专科协同护理可改善老年重症COVID-19合并并发症患者的预后。严重程度分层可确保对COVID-19严重疾病及时提供挽救生命的护理。
{"title":"Lessons Learnt from the Management of Severe COVID-19 Disease in a 93-year-old with Chronic Co-Morbidities at a Resource-constrained Centre in Nigeria – A Retrospective Single Case Study","authors":"C. B. Nwatu, O. Anyim, U. Unigwe","doi":"10.9734/ijtdh/2023/v44i101434","DOIUrl":"https://doi.org/10.9734/ijtdh/2023/v44i101434","url":null,"abstract":"Introduction: Severe COVID-19 infection is associated with significant mortality in the elderly. This is even more so, when the elderly patient with the disease also has multiple chronic co-morbidities, and is resident in a resource-constrained area. \u0000Aims/ Objectives: To outline management strategies employed, and important lessons learnt from the successful management of a case of severe COVID-19 disease in a 93-year-old with chronic co-morbidities in a resource-limited setting. \u0000Methods: We utilized a simple COVID-19 severity categorization algorithm on presentation, to assign the index patient to the appropriate COVID-19 disease severity class and subsequently employed patient’s serial, weekly clinical and laboratory parameters to guide a multi-specialty management protocol. \u0000Results: A 93-year-old man was referred to a tertiary hospital in Enugu during the second wave of the COVID-19 pandemic, with a 5-day-history of high grade fever, severe fatigue, and altered sensorium. He had been living with diabetes for 48years; recently had worsening glycemic control, and was yet to pass urine in the previous 12hours. He was also being managed conservatively for prostate carcinoma. Examination revealed signs of severe pneumonia and he was drowsy, dehydrated, and had asterixis. A diagnosis of acute kidney injury from septicemia, following community acquired pneumonia and possibly urinary tract infection was made, with COVID-19 infection as a differential. Samples were collected for laboratory investigations while he was recommended for intensive care unit admission for further care. Para-enteral broad spectrum antibiotics, intravenous fluid therapy, intranasal oxygen therapy, basal-bolus-insulin-regimen, and anti-coagulation prophylaxis were instituted. Following laboratory investigation results which included a positive COVID-19 test (clinically categorized as severe disease), severe systemic inflammation, evidence of uro-tract infection, intravascular thrombosis and severe renal impairment, the Nephrology, Infectious disease, Urology teams were invited to co-manage the patient alongside the Endocrinologists. After 27days of collaborative care, patient was discharged with resolution of his symptoms and signs. \u0000Conclusion: Multi-specialty collaborative care improves patients’ outcome even in the face of severe COVID-19 with associated co-morbidities in elderly patients. Severity stratification ensures life-saving timely care for severe COVID-19 disease.","PeriodicalId":126794,"journal":{"name":"International Journal of TROPICAL DISEASE &amp; Health","volume":"223 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120881865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of a Tertiary Hospital’s Systems Thinking Approach Using the World Health Organization Health System Framework in Response to the COVID-19 Pandemic in Nigeria 利用世界卫生组织卫生系统框架评估三级医院应对尼日利亚COVID-19大流行的系统思维方法
Pub Date : 2023-06-05 DOI: 10.9734/ijtdh/2023/v44i101433
C. B. Nwatu
Background: The coronavirus disease 2019, (COVID-19) pandemic dealt a catastrophic blow to health systems globally, especially those of middle and low-income-countries, whose health systems were already frail, pre-pandemic. The World Health Organization (WHO) recognizes six building blocks (BBs) for a sturdy health system, whose synergistic interaction, through a systems thinking approach, guarantees optimal and equitable health outcomes for the populace, while shielding them from financial risk.  Objectives: To showcase a Nigerian tertiary hospital’s response to the COVID-19 pandemic, through the application of systems thinking, to the WHO health systems BBs. Methods: A questionnaire-based survey (utilizing a Likert scale of 1=very poor; 2=poor; 3=fair; 4=good and 5=excellent) of the hospital-wide efforts, employed by the leadership of the University of Nigeria Teaching Hospital (UNTH) Enugu, utilizing the WHO BBs, during the COVID-19 pandemic, assessed the perceived impact of the individual BBs on the hospital system. Eighty key stakeholders (Females=55%), heads of departments and supervisors, comprising various categories of medical personnel, overseeing twenty critical service areas of the hospital undertook the survey. Results: Leadership/Governance ranked highest in impact among the BBs (68.6%), with the availability of Medical products/Technology (65.9%), and Service delivery (64.4%) trailing closely at second and third, respectively. Perceived robustness and overall motivation of the Health Workforce was least ranked at 57.1%, closely followed by Healthcare Financing (58.2%) and Health Information Systems (61.9%). Conclusion: At an average cumulative score of 62.7% for all the BBs, the UNTH leadership may be adjudged to have performed creditably in their efforts at COVID-19 containment. Staff welfare should be enhanced, to ensure a well-motivated staff which will likely translate to improved service delivery.   
背景:2019年冠状病毒病(COVID-19)大流行对全球卫生系统造成了灾难性打击,特别是中低收入国家的卫生系统,这些国家的卫生系统在大流行前就已经脆弱不堪。世界卫生组织(世卫组织)确认了一个坚固的卫生系统的六个组成部分,通过系统思维方法,这些组成部分的协同作用保证了民众获得最佳和公平的卫生结果,同时保护他们免受财务风险。目的:通过将系统思维应用于世卫组织卫生系统论坛,展示尼日利亚一家三级医院应对COVID-19大流行的情况。方法:采用问卷调查法(采用李克特量表,1=非常差;2 =差;3 =公平;在2019冠状病毒病大流行期间,尼日利亚大学埃努古教学医院(UNTH)领导利用世卫组织论坛,评估了各个论坛对医院系统的感知影响,对医院范围内的工作进行了4=良好和5=优秀)。80名主要利益相关者(女性=55%)、部门负责人和主管,包括监督医院20个关键服务领域的各类医务人员,参与了调查。结果:领导力/治理在论坛中的影响力排名最高(68.6%),医疗产品/技术的可用性(65.9%)和服务提供(64.4%)紧随其后,分别排在第二和第三位。卫生人力的感知稳健性和整体动机排名最低,为57.1%,紧随其后的是医疗融资(58.2%)和卫生信息系统(61.9%)。结论:所有论坛的平均累积得分为62.7%,可以判断UNTH领导层在COVID-19控制方面的努力是值得赞扬的。应加强员工福利,以确保员工积极性高,从而可能转化为改善服务。
{"title":"Assessment of a Tertiary Hospital’s Systems Thinking Approach Using the World Health Organization Health System Framework in Response to the COVID-19 Pandemic in Nigeria","authors":"C. B. Nwatu","doi":"10.9734/ijtdh/2023/v44i101433","DOIUrl":"https://doi.org/10.9734/ijtdh/2023/v44i101433","url":null,"abstract":"Background: The coronavirus disease 2019, (COVID-19) pandemic dealt a catastrophic blow to health systems globally, especially those of middle and low-income-countries, whose health systems were already frail, pre-pandemic. The World Health Organization (WHO) recognizes six building blocks (BBs) for a sturdy health system, whose synergistic interaction, through a systems thinking approach, guarantees optimal and equitable health outcomes for the populace, while shielding them from financial risk.  \u0000Objectives: To showcase a Nigerian tertiary hospital’s response to the COVID-19 pandemic, through the application of systems thinking, to the WHO health systems BBs. \u0000Methods: A questionnaire-based survey (utilizing a Likert scale of 1=very poor; 2=poor; 3=fair; 4=good and 5=excellent) of the hospital-wide efforts, employed by the leadership of the University of Nigeria Teaching Hospital (UNTH) Enugu, utilizing the WHO BBs, during the COVID-19 pandemic, assessed the perceived impact of the individual BBs on the hospital system. Eighty key stakeholders (Females=55%), heads of departments and supervisors, comprising various categories of medical personnel, overseeing twenty critical service areas of the hospital undertook the survey. \u0000Results: Leadership/Governance ranked highest in impact among the BBs (68.6%), with the availability of Medical products/Technology (65.9%), and Service delivery (64.4%) trailing closely at second and third, respectively. Perceived robustness and overall motivation of the Health Workforce was least ranked at 57.1%, closely followed by Healthcare Financing (58.2%) and Health Information Systems (61.9%). \u0000Conclusion: At an average cumulative score of 62.7% for all the BBs, the UNTH leadership may be adjudged to have performed creditably in their efforts at COVID-19 containment. Staff welfare should be enhanced, to ensure a well-motivated staff which will likely translate to improved service delivery.   ","PeriodicalId":126794,"journal":{"name":"International Journal of TROPICAL DISEASE &amp; Health","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125125400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterization and Profiling of Gut Bacterial Microbiome and Pathobionts among HIV-negative and HIV-infected Individuals in Cameroon 喀麦隆艾滋病毒阴性和艾滋病毒感染者肠道细菌微生物组和病原体的特征和分析
Pub Date : 2023-05-26 DOI: 10.9734/ijtdh/2023/v44i91431
S. Ako, C. Nkenfou, J. N. Assob, T. B. Pokam, M. Ngemenya, R. Ndip, A. Nota, M. Tongo, Christopher Njopin, Enoh Jude Eteneneng, F. Cho, Mbanya Gladice Mbanya, Woguia Gilles-Fils, Ngoume Moukoma Y. Franck, E. Akum
Background: Knowledge of the core gut microbiome among Cameroonians is a preliminary step for a better implementation of treatment strategies to correct dysbiosis and improve health care management. HIV infection has continued to cause high mortality among those infected, but the types and frequency of human gut microbiota associated with or without HIV/AIDS presence have not been identified in the adult populations in Cameroon. Methods: This was a case-control and comparative study design that ran from June 2018 to September 2019. Stool Samples were purposively collected from 40 participants (15 HIV-negative and 25 HIV-positive) for the 16S rRNA gene sequencing on the next-generation Illumina® MiSeq™ sequencer. Blood samples were collected for HIV determine testing, CD4 Tcell count, and HIV viral load. Sequences were clustered into operational taxonomic units (OTUs) at ninety-nine percent identity and their representatives were accustomed to using a phylogenetic approach. Results: The study showed a phylogenetic taxonomy of the gut microbiome communities in two kingdoms (Archea and Bacteria) and eight Phylum [Firmicutes (44.7%), Bacteroidetes (43.7%), Proteobacteria (8.7%), Actinobacteria (1%), Fusobacteria (0.2%), Euryarchaeota (0.01%), Synergistetes (0.01%), Verrucomicrobia (0.01%) and unclassified phylum (1.7%)]. A total of 347 gut microbiota species were identified, including 55 unique species/oligotypes, and 28 pathobionts from the study population. HIV infection was characterized by significant gut microbiota compositional changes with HIV-positive less diverse (56 strains absent) with significantly increased OTUs of the butyrate-producing microbiome species as compared to HIV-negative individuals (p=0.001). Conclusions: A profile of 347 gut microbiome bacterial species was identified in the Cameroonian community. Particularly, from the 347 gut microbiome bacterial species profiled, eight phyla were identified, with 55 unique species/oligotypes containing more than one sequence and 28 pathobionts. A host of unknown/unclassified gut microbiome bacterial species were also noted circulating among the study population.
背景:了解喀麦隆人的核心肠道微生物群是更好地实施治疗策略以纠正生态失调和改善卫生保健管理的初步步骤。艾滋病毒感染继续在感染者中造成高死亡率,但在喀麦隆的成年人口中,与艾滋病毒/艾滋病存在与否相关的人类肠道微生物群的类型和频率尚未确定。方法:采用病例对照和比较研究设计,研究时间为2018年6月至2019年9月。有目的地从40名参与者(15名hiv阴性和25名hiv阳性)中收集粪便样本,在下一代Illumina®MiSeq™测序仪上进行16S rRNA基因测序。采集血样进行HIV检测、CD4 t细胞计数和HIV病毒载量检测。序列以99%的同一性聚类成操作分类单位(otu),它们的代表习惯于使用系统发育方法。结果:本研究获得了两门(古细菌门和古细菌门)和8门(厚壁菌门(44.7%)、拟杆菌门(43.7%)、变形菌门(8.7%)、放线菌门(1%)、梭菌门(0.2%)、Euryarchaeota(0.01%)、Synergistetes(0.01%)、Verrucomicrobia(0.01%)和未分类门(1.7%))肠道微生物群落的系统发育分类。共鉴定出347种肠道微生物,包括55种独特的物种/寡型,以及来自研究人群的28种病原体。HIV感染的特征是肠道菌群组成发生显著变化,HIV阳性个体的肠道菌群多样性较低(56株缺失),与HIV阴性个体相比,产生丁酸盐的微生物群物种的OTUs显著增加(p=0.001)。结论:在喀麦隆社区中鉴定了347种肠道微生物组细菌。特别是,在347种肠道微生物组细菌中,鉴定出8门,55种独特的物种/寡型含有多个序列和28种病原体。在研究人群中还发现了大量未知/未分类的肠道微生物菌群。
{"title":"Characterization and Profiling of Gut Bacterial Microbiome and Pathobionts among HIV-negative and HIV-infected Individuals in Cameroon","authors":"S. Ako, C. Nkenfou, J. N. Assob, T. B. Pokam, M. Ngemenya, R. Ndip, A. Nota, M. Tongo, Christopher Njopin, Enoh Jude Eteneneng, F. Cho, Mbanya Gladice Mbanya, Woguia Gilles-Fils, Ngoume Moukoma Y. Franck, E. Akum","doi":"10.9734/ijtdh/2023/v44i91431","DOIUrl":"https://doi.org/10.9734/ijtdh/2023/v44i91431","url":null,"abstract":"Background: Knowledge of the core gut microbiome among Cameroonians is a preliminary step for a better implementation of treatment strategies to correct dysbiosis and improve health care management. HIV infection has continued to cause high mortality among those infected, but the types and frequency of human gut microbiota associated with or without HIV/AIDS presence have not been identified in the adult populations in Cameroon. \u0000Methods: This was a case-control and comparative study design that ran from June 2018 to September 2019. Stool Samples were purposively collected from 40 participants (15 HIV-negative and 25 HIV-positive) for the 16S rRNA gene sequencing on the next-generation Illumina® MiSeq™ sequencer. Blood samples were collected for HIV determine testing, CD4 Tcell count, and HIV viral load. Sequences were clustered into operational taxonomic units (OTUs) at ninety-nine percent identity and their representatives were accustomed to using a phylogenetic approach. \u0000Results: The study showed a phylogenetic taxonomy of the gut microbiome communities in two kingdoms (Archea and Bacteria) and eight Phylum [Firmicutes (44.7%), Bacteroidetes (43.7%), Proteobacteria (8.7%), Actinobacteria (1%), Fusobacteria (0.2%), Euryarchaeota (0.01%), Synergistetes (0.01%), Verrucomicrobia (0.01%) and unclassified phylum (1.7%)]. A total of 347 gut microbiota species were identified, including 55 unique species/oligotypes, and 28 pathobionts from the study population. HIV infection was characterized by significant gut microbiota compositional changes with HIV-positive less diverse (56 strains absent) with significantly increased OTUs of the butyrate-producing microbiome species as compared to HIV-negative individuals (p=0.001). \u0000Conclusions: A profile of 347 gut microbiome bacterial species was identified in the Cameroonian community. Particularly, from the 347 gut microbiome bacterial species profiled, eight phyla were identified, with 55 unique species/oligotypes containing more than one sequence and 28 pathobionts. A host of unknown/unclassified gut microbiome bacterial species were also noted circulating among the study population.","PeriodicalId":126794,"journal":{"name":"International Journal of TROPICAL DISEASE &amp; Health","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123608268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Unique Community of Gut Bacterial Microbiome as Indicator for HIV Infection and Progression 独特的肠道细菌微生物群落作为HIV感染和进展的指标
Pub Date : 2023-05-25 DOI: 10.9734/ijtdh/2023/v44i91430
S. Ako, C. Nkenfou, J. N. Assob, T. B. Pokam, M. Tongo, Enoh Jude Eteneneng, Mbanya Gladice Mbanya, E. Akum
The human digestive tract harbors complex microbial communities within its epithelial cell lining. Disruption in enteric immunity will promote gut dysbiosis, which can successively induce chronic inflammation within the mucous membrane and periphery. Interpretation of the specific gut microbiome changes observed during HIV infection is warranted in populations most affected.This was a case-control and comparative study design carried out between June 2018 to September 2019. A total of 40 volunteer adult participants were recruited (15 HIV-negative and 25 HIV-positive) at the Buea Regional Hospital. Blood analysis was done for CD4+ T cell count and HIV viral load. Fecal samples from all participants were analyzed using the 16S rRNA gene sequencing on the next-generation Illumina® MiSeq™ sequencer. Biomarker Linear Discriminant Analysis (LDA) score from LEfSe analysis indicated that the specific gut microbiome, Lachnoclostridium sp32343-sp32393-sp32423 communities could serve as an indicator for HIV infection. Findings also showed that Bacteroides vulgatus (seq 11 & seq 42), Megamonas funiformis (seq 63), unclassified members of Prevotallaceae family sp14289 (seq 51), sp13942 (seq 4), and Prevotella copri-sp13942 (seq 5) could be used as gut microbiome biomarkers for increased HIV viral load and decreased CD4+ T cell count. Meanwhile gut microbiome biomarkers for decreased HIV viral load and increased CD4+ T cell count were identified as Succinivibrionaceae sp56244 (seq 47),  Eubacterium rectale (seq 8), Megamonas funiformis (seq 1 and seq 14), Prevotella copri (seq 29, seq 34, and seq 12) and unclassified Prevotellaceae sp13927 (seq 17), sp13942 (seq 5). Specific gut microbiome communities of Lachnoclostridium sp32343-sp32393-sp32423 could be used as an indicator of HIV presence. Some gut bacteria microbiome can be utilized in the management of HIV disease progression.
人类消化道的上皮细胞内层蕴藏着复杂的微生物群落。肠道免疫紊乱会促进肠道生态失调,进而诱发粘膜和外周慢性炎症。在最受影响的人群中,对HIV感染期间观察到的特定肠道微生物组变化的解释是有必要的。这是一项病例对照和比较研究设计,于2018年6月至2019年9月进行。在布埃亚地区医院共招募了40名成年志愿者(15名艾滋病毒阴性,25名艾滋病毒阳性)。血液分析CD4+ T细胞计数和HIV病毒载量。使用下一代Illumina®MiSeq™测序仪对所有参与者的粪便样本进行16S rRNA基因测序分析。生物标志物线性判别分析(LDA)结果表明,特异性肠道微生物群Lachnoclostridium sp32343-sp32393-sp32423群落可以作为HIV感染的指标。研究结果还表明,普通拟杆菌(seq 11和seq 42)、异种大单胞菌(seq 63)、普雷沃菌科未分类成员sp14289 (seq 51)、sp13942 (seq 4)和copi -普雷沃菌sp13942 (seq 5)可作为HIV病毒载量升高和CD4+ T细胞计数降低的肠道微生物组生物标志物。与此同时,肠道微生物组生物标志物鉴定出降低HIV病毒载量和增加CD4+ T细胞计数的有Succinivibrionaceae sp56244 (seq 47)、Eubacterium rectale (seq 8)、Megamonas funiformis (seq 1和seq 14)、Prevotella copri (seq 29、seq 34和seq 12)和未分类的Prevotellaceae sp13927 (seq 17)、sp13942 (seq 5)。Lachnoclostridium sp32343-sp32393-sp32423的特异性肠道微生物群落可以作为HIV存在的指标。一些肠道细菌微生物组可用于艾滋病毒疾病进展的管理。
{"title":"Unique Community of Gut Bacterial Microbiome as Indicator for HIV Infection and Progression","authors":"S. Ako, C. Nkenfou, J. N. Assob, T. B. Pokam, M. Tongo, Enoh Jude Eteneneng, Mbanya Gladice Mbanya, E. Akum","doi":"10.9734/ijtdh/2023/v44i91430","DOIUrl":"https://doi.org/10.9734/ijtdh/2023/v44i91430","url":null,"abstract":"The human digestive tract harbors complex microbial communities within its epithelial cell lining. Disruption in enteric immunity will promote gut dysbiosis, which can successively induce chronic inflammation within the mucous membrane and periphery. Interpretation of the specific gut microbiome changes observed during HIV infection is warranted in populations most affected.This was a case-control and comparative study design carried out between June 2018 to September 2019. A total of 40 volunteer adult participants were recruited (15 HIV-negative and 25 HIV-positive) at the Buea Regional Hospital. Blood analysis was done for CD4+ T cell count and HIV viral load. Fecal samples from all participants were analyzed using the 16S rRNA gene sequencing on the next-generation Illumina® MiSeq™ sequencer. \u0000Biomarker Linear Discriminant Analysis (LDA) score from LEfSe analysis indicated that the specific gut microbiome, Lachnoclostridium sp32343-sp32393-sp32423 communities could serve as an indicator for HIV infection. Findings also showed that Bacteroides vulgatus (seq 11 & seq 42), Megamonas funiformis (seq 63), unclassified members of Prevotallaceae family sp14289 (seq 51), sp13942 (seq 4), and Prevotella copri-sp13942 (seq 5) could be used as gut microbiome biomarkers for increased HIV viral load and decreased CD4+ T cell count. Meanwhile gut microbiome biomarkers for decreased HIV viral load and increased CD4+ T cell count were identified as Succinivibrionaceae sp56244 (seq 47),  Eubacterium rectale (seq 8), Megamonas funiformis (seq 1 and seq 14), Prevotella copri (seq 29, seq 34, and seq 12) and unclassified Prevotellaceae sp13927 (seq 17), sp13942 (seq 5). Specific gut microbiome communities of Lachnoclostridium sp32343-sp32393-sp32423 could be used as an indicator of HIV presence. Some gut bacteria microbiome can be utilized in the management of HIV disease progression.","PeriodicalId":126794,"journal":{"name":"International Journal of TROPICAL DISEASE &amp; Health","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129496719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Knowledge and Management of Buruli Ulcer Disease: A Case Study at Sekyere Afram Plains District of Ashanti Region, Ghana 布鲁里溃疡疾病的知识和管理:以加纳阿散蒂地区塞基尔阿夫拉姆平原地区为例
Pub Date : 2023-05-19 DOI: 10.9734/ijtdh/2023/v44i91428
Philip Gyaase, Michael Kobina Lindsay, Emmanuel Boateng Acheampong, D. Sampson
Introduction: The goal of the study was to assess the knowledge and management of Buruli ulcer disease in the Sekyere Afram Plains District of Ashanti Region. Methods: The study used a quantitative study type and cross-sectional study design with a sample size of 251 comprising Buruli Ulcer (BU) patients, health workers and community members as study population. The study used a structured questionnaire for the primary data. The questionnaire was used because the respondents were literates and could read and respond to the items without difficulty. Data collected were edited and coded and statistically analyzed using Statistical Package for the Social Sciences (SPSS) version 26 software. Inferential and Descriptive statistics such as frequencies and percentages were used to describe the study variables. Chi-square (p-values) was used and the data were analyzed in Tables with significance level set at 0.05. Results: The results revealed that the patient’s knowledge, about BU was 61.9% which was statistically significant (p-value= <0.001). It also revealed association between knowledge on Buruli ulcer and demographic characteristics of respondents (p-value =<0.001). Relatively colossal number of respondents (81.0%) revealed that they were not an active member of National Health Insurance Scheme (NHIS). Conclusion: The study concludes that if health workers are trained on BU and more education is given to the community members on Buruli ulcer disease, their health seeking behaviour would be improved to reduce complications associated with Buruli ulcer disease in the District. The study recommends that Ghana Health Service (GHS) should organize training and refresher courses for health care workers to increase their knowledge on Buruli ulcer.
本研究的目的是评估阿散蒂地区Sekyere Afram平原地区布鲁里溃疡疾病的知识和管理。方法:本研究采用定量研究类型和横断面研究设计,样本量为251人,包括布鲁里溃疡(BU)患者、卫生工作者和社区成员作为研究人群。本研究采用结构化问卷作为主要数据。使用问卷调查是因为受访者是文盲,可以阅读和回答项目没有困难。收集的数据进行编辑、编码,并使用社会科学统计软件包(SPSS)第26版软件进行统计分析。使用频率和百分比等推理和描述性统计来描述研究变量。采用卡方(p值),以表进行数据分析,显著性水平设为0.05。结果:患者对BU的知知率为61.9%,差异有统计学意义(p值= <0.001)。它还揭示了布鲁里溃疡知识与受访者人口统计学特征之间的关联(p值=<0.001)。相当多的受访者(81.0%)表示,他们不是国家健康保险计划(NHIS)的积极成员。结论:研究得出的结论是,如果对保健工作者进行布鲁里溃疡方面的培训,并向社区成员提供更多布鲁里溃疡疾病的教育,他们的求医行为将得到改善,从而减少该地区与布鲁里溃疡疾病相关的并发症。该研究建议加纳卫生局(GHS)应为卫生保健工作者组织培训和进修课程,以增加他们对布鲁里溃疡的认识。
{"title":"Knowledge and Management of Buruli Ulcer Disease: A Case Study at Sekyere Afram Plains District of Ashanti Region, Ghana","authors":"Philip Gyaase, Michael Kobina Lindsay, Emmanuel Boateng Acheampong, D. Sampson","doi":"10.9734/ijtdh/2023/v44i91428","DOIUrl":"https://doi.org/10.9734/ijtdh/2023/v44i91428","url":null,"abstract":"Introduction: The goal of the study was to assess the knowledge and management of Buruli ulcer disease in the Sekyere Afram Plains District of Ashanti Region. \u0000Methods: The study used a quantitative study type and cross-sectional study design with a sample size of 251 comprising Buruli Ulcer (BU) patients, health workers and community members as study population. The study used a structured questionnaire for the primary data. The questionnaire was used because the respondents were literates and could read and respond to the items without difficulty. Data collected were edited and coded and statistically analyzed using Statistical Package for the Social Sciences (SPSS) version 26 software. Inferential and Descriptive statistics such as frequencies and percentages were used to describe the study variables. Chi-square (p-values) was used and the data were analyzed in Tables with significance level set at 0.05. \u0000Results: The results revealed that the patient’s knowledge, about BU was 61.9% which was statistically significant (p-value= <0.001). It also revealed association between knowledge on Buruli ulcer and demographic characteristics of respondents (p-value =<0.001). Relatively colossal number of respondents (81.0%) revealed that they were not an active member of National Health Insurance Scheme (NHIS). \u0000Conclusion: The study concludes that if health workers are trained on BU and more education is given to the community members on Buruli ulcer disease, their health seeking behaviour would be improved to reduce complications associated with Buruli ulcer disease in the District. The study recommends that Ghana Health Service (GHS) should organize training and refresher courses for health care workers to increase their knowledge on Buruli ulcer.","PeriodicalId":126794,"journal":{"name":"International Journal of TROPICAL DISEASE &amp; Health","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130891679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Overview of COVID-19 and Its Progression in Ghana COVID-19概述及其在加纳的进展
Pub Date : 2023-05-19 DOI: 10.9734/ijtdh/2023/v44i91429
J. Apenteng, Samuel Korsah, Miriam Tagoe, A. Sarfo
This research focuses on the progression of the coronavirus pandemic in Ghana, measures put in place to fight the pandemic and evaluation of Ghana’s response in terms of both containing the pandemic and mitigating the social and economic effects of the COVID 19 pandemic. Methods: The study mainly assessed the COVID-19 situation in Ghana within the period of March 2020 to MAY 2021. Data from reputable sources; Ministry of Health, Goggle scholar, Ghana Health Service, CDC, WHO, WTTC and online news articles were retrieved and assessed in quarterly basis. The results were further tabulated and graphically represented using Microsoft Excel application. Results: A total of 94011 cases were recorded by the end of the of May 2021; first quarter of the second year. The highest number of active cases (11897), deaths (295) and critical cases (280) recorded were from December 2020 to February 2021. In the first quarter, the infection rate recorded was 3.77% which increased to 16.10% in the second quarter. However, with reinforcement of the COVID-19 protocol there was a significant decrease in infection rate in the final quarter for the studies; from March to May 2021 (3.60%). Conclusion: Actions adopted by the Ghanaian government so far in handling the pandemic have generated significant achievements. It is however recommended that more control measures such as mass vaccination, mass testing and contact tracing will help track the infection and further reduce the rate of infection.
本研究的重点是加纳冠状病毒大流行的进展、为抗击大流行而采取的措施,以及从遏制大流行和减轻COVID - 19大流行的社会和经济影响两方面评估加纳的应对措施。方法:本研究主要评估2020年3月至2021年5月期间加纳的COVID-19情况。数据来自信誉良好的来源;每季度检索和评估卫生部、gogle学者、加纳卫生服务、疾病预防控制中心、世卫组织、WTTC和在线新闻文章。使用Microsoft Excel应用程序将结果进一步制成表格并图形化表示。结果:截至2021年5月底,共记录病例94011例;第二年的第一季度。活跃病例(11897例)、死亡病例(295例)和危重病例(280例)的最高记录发生在2020年12月至2021年2月。第一季度的感染率为3.77%,第二季度上升至16.10%。然而,随着COVID-19方案的加强,研究的最后一个季度感染率显着下降;2021年3月至5月(3.60%)。结论:加纳政府迄今在应对疫情方面采取的行动取得了重大成就。然而,建议采取更多控制措施,如大规模疫苗接种、大规模检测和接触者追踪,将有助于追踪感染并进一步降低感染率。
{"title":"An Overview of COVID-19 and Its Progression in Ghana","authors":"J. Apenteng, Samuel Korsah, Miriam Tagoe, A. Sarfo","doi":"10.9734/ijtdh/2023/v44i91429","DOIUrl":"https://doi.org/10.9734/ijtdh/2023/v44i91429","url":null,"abstract":"This research focuses on the progression of the coronavirus pandemic in Ghana, measures put in place to fight the pandemic and evaluation of Ghana’s response in terms of both containing the pandemic and mitigating the social and economic effects of the COVID 19 pandemic. \u0000Methods: The study mainly assessed the COVID-19 situation in Ghana within the period of March 2020 to MAY 2021. Data from reputable sources; Ministry of Health, Goggle scholar, Ghana Health Service, CDC, WHO, WTTC and online news articles were retrieved and assessed in quarterly basis. The results were further tabulated and graphically represented using Microsoft Excel application. \u0000Results: A total of 94011 cases were recorded by the end of the of May 2021; first quarter of the second year. The highest number of active cases (11897), deaths (295) and critical cases (280) recorded were from December 2020 to February 2021. In the first quarter, the infection rate recorded was 3.77% which increased to 16.10% in the second quarter. However, with reinforcement of the COVID-19 protocol there was a significant decrease in infection rate in the final quarter for the studies; from March to May 2021 (3.60%). \u0000Conclusion: Actions adopted by the Ghanaian government so far in handling the pandemic have generated significant achievements. It is however recommended that more control measures such as mass vaccination, mass testing and contact tracing will help track the infection and further reduce the rate of infection.","PeriodicalId":126794,"journal":{"name":"International Journal of TROPICAL DISEASE &amp; Health","volume":"177 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132932709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mathematical Models and Societal Impact of COVID-19 Pandemic: A Short Review COVID-19大流行的数学模型和社会影响:简要综述
Pub Date : 2023-05-16 DOI: 10.9734/ijtdh/2023/v44i91427
Achintya Bhattacharyya, J. Mukherjee
In this article we present a short and informative review on growth and impact of novel corona virus appeared in 2019. Almost entire world has been is the victim of this life-threatening virus. Here, we have discussed the growth of the COVID 19 in different parts of the world and how they are mathematically modelled. We have also discussed how different mathematical models predicts the minimisation of the growth by predicting the minimum days of lockdown. Further, the effect of effect of lockdown in everyday life and its societal impact are also highlighted.
在本文中,我们对2019年出现的新型冠状病毒的生长和影响进行了简短而翔实的回顾。几乎整个世界都是这种威胁生命的病毒的受害者。在这里,我们讨论了COVID - 19在世界不同地区的增长情况,以及如何对其进行数学建模。我们还讨论了不同的数学模型如何通过预测封锁的最短天数来预测增长的最小化。此外,还强调了封锁对日常生活的影响及其社会影响。
{"title":"Mathematical Models and Societal Impact of COVID-19 Pandemic: A Short Review","authors":"Achintya Bhattacharyya, J. Mukherjee","doi":"10.9734/ijtdh/2023/v44i91427","DOIUrl":"https://doi.org/10.9734/ijtdh/2023/v44i91427","url":null,"abstract":"In this article we present a short and informative review on growth and impact of novel corona virus appeared in 2019. Almost entire world has been is the victim of this life-threatening virus. Here, we have discussed the growth of the COVID 19 in different parts of the world and how they are mathematically modelled. We have also discussed how different mathematical models predicts the minimisation of the growth by predicting the minimum days of lockdown. Further, the effect of effect of lockdown in everyday life and its societal impact are also highlighted.","PeriodicalId":126794,"journal":{"name":"International Journal of TROPICAL DISEASE &amp; Health","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116942091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
International Journal of TROPICAL DISEASE &amp; Health
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1