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Pyruvate in Aqueous Media Probed by Mid-Infrared Quantum Spectroscopy Based on Induced Coherence 基于诱导相干的中红外量子光谱探测水介质中的丙酮酸盐
IF 5.1 2区 工程技术 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-12-08 DOI: 10.1109/JSTQE.2025.3641631
Lin Cheng;Yu Chen;Yujie Cai;Xiaoying Wang;Yihan Jia;Kun Huang;E Wu
As a key intermediate in energy metabolism, pyruvate concentration can reflect cellular metabolic status. Conventional methods such as enzymatic colorimetric assays offer high sensitivity, but rely on fresh reagents and can modify or deplete the target analyte. Mid-infrared (MIR) spectroscopy simplifies the measurement. However, conventional MIR detection is constrained by limited MIR detector sensitivity and high background noise. Here we present an induced-coherence MIR quantum spectroscopy system that requires neither MIR sources nor detectors. Using a nonlinear Michelson interferometer with an AgGaSe2 crystal (type-I nondegenerate SPDC), we achieve the MIR spectral characterization of pyruvate at 8.5 μm (≈1176 cm−1), corresponding to the C–C vibrational band, while only the near-infrared signal photons are detected. A 10-μm-path liquid cell containing 5 μL of pyruvate solution in ultrapure water and simulated body fluid (SBF) is inserted in the MIR interferometer arm. The absorbance spectra retrieved from quantum interferograms via fast Fourier transform agree with those obtained by conventional MIR spectroscopy using the same sample. Using only near-infrared detection, we perform rapid scans near the zero-path-difference position, enabling nondestructive, label-free quantitative analysis of microliter-scale samples and establishing a linear response to pyruvate concentration. These results highlight the potential of quantum spectroscopy for biomedical sensing and provide a foundation for high-sensitivity MIR spectral analysis in complex physiological environments.
丙酮酸作为能量代谢的关键中间体,其浓度可以反映细胞的代谢状态。传统的方法,如酶比色测定法提供高灵敏度,但依赖于新鲜试剂,并且可以修饰或耗尽目标分析物。中红外光谱(MIR)简化了测量。然而,传统的MIR检测受到检测器灵敏度有限和高背景噪声的限制。在这里,我们提出了一个感应相干MIR量子光谱系统,既不需要MIR源也不需要探测器。利用AgGaSe2晶体(i型非简并SPDC)的非线性迈克尔逊干涉仪,我们在C-C振动带对应的8.5 μm(≈1176 cm−1)处实现了丙酮酸盐的MIR光谱表征,而仅检测到近红外信号光子。在MIR干涉仪臂中插入一个10 μm径的液池,其中含有5 μL的超纯水和模拟体液(SBF)中的丙酮酸溶液。通过快速傅立叶变换从量子干涉图中获得的吸光度光谱与使用相同样品的传统MIR光谱获得的吸光度光谱一致。仅使用近红外检测,我们在零路径差位置附近进行快速扫描,实现对微升尺度样品的无损,无标记定量分析,并建立对丙酮酸浓度的线性响应。这些结果突出了量子光谱在生物医学传感领域的潜力,为在复杂生理环境中进行高灵敏度MIR光谱分析提供了基础。
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引用次数: 0
Guest Editorial: When Photonics Meets Climate Mitigation: The Evolution of Knowledge Through Scientific Discourse 客座评论:当光子学满足气候减缓:通过科学话语知识的演变
IF 5.1 2区 工程技术 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-12-08 DOI: 10.1109/JSTQE.2025.3633926
Qiaoqiang Gan;Aaswath Raman
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引用次数: 0
Editorial Interview: The Cool Power of Light 编辑采访:光的酷力量
IF 5.1 2区 工程技术 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-12-08 DOI: 10.1109/JSTQE.2025.3633465
Shanhui Fan
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引用次数: 0
Editorial: Photonics for Climate Change Adaptation and Mitigation 社论:适应和减缓气候变化的光子学
IF 5.1 2区 工程技术 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-12-08 DOI: 10.1109/JSTQE.2025.3638176
Aaswath Raman
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引用次数: 0
Micro-Transfer-Printed Heterogeneous Thin-Film Lithium Niobate Mach–Zehnder Modulator on Silicon With Low-Loss Inter-Layer Coupler 低损耗层间耦合器微转移印刷非均质铌酸锂薄膜马赫曾德调制器
IF 5.1 2区 工程技术 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-12-08 DOI: 10.1109/JSTQE.2025.3641391
Toshiya Murai;Rai Kou;Guangwei Cong;Yohei Yamashita;Masahiko Imai;Kazumasa Takabayashi;Koji Yamada
Micro-transfer printing (µ-TP) enables high-density integration of pre-structure-defined device coupons, facilitating multiple photonic functions on a single chip after the CMOS back-end-of-line process. This study demonstrates µ-TP of a pre-structured thin-film lithium-niobate (TFLN) coupon with two parallel etched TFLN waveguides onto a silicon photonics (SiPh) platform, achieving a 3σ alignment accuracy of approximately 0.5 μm. It incorporates low-loss design-optimized inter-layer couplers with a minimum transition loss of less than 0.1 dB and traveling-wave coplanar electrodes. The Si/TFLN hybrid Mach–Zehnder modulator achieves an on-chip device loss of 1.0 dB and a 3-dB EO bandwidth exceeding 67 GHz. This represents the first µ-TP integration of pre-structured TFLN waveguides with low-loss inter-layer coupling on a SiPh platform, marking a significant advancement in scalable, high-performance photonic integration.
微转移印刷(µ-TP)实现了预先结构定义器件的高密度集成,在CMOS后端工艺之后,促进了单个芯片上的多个光子功能。本研究展示了一种具有两个平行蚀刻TFLN波导的预结构薄膜铌酸锂(TFLN)贴片在硅光子学(SiPh)平台上的微tp,实现了约0.5 μm的3σ对准精度。它采用低损耗设计优化的层间耦合器,最小过渡损耗小于0.1 dB,并采用行波共面电极。Si/TFLN混合Mach-Zehnder调制器实现了片上器件损耗为1.0 dB和超过67 GHz的3db EO带宽。这是在SiPh平台上首次将预结构TFLN波导与低损耗层间耦合集成在一起,标志着可扩展、高性能光子集成的重大进步。
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引用次数: 0
Thermal Challenges for Resonant Si Photonic Modulators in System-on-Wafer Applications 谐振硅光子调制器在片上系统应用中的热挑战
IF 5.1 2区 工程技术 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-12-08 DOI: 10.1109/JSTQE.2025.3641312
David Coenen;Minkyu Kim;Herman Oprins;Xinyue Chang;Filippo Ferraro;Yoojin Ban;Joris Van Campenhout
Recent developments in system-on-wafer high-performance compute systems have delivered promising results for alleviating the memory wall encountered in AI/ML training workloads. This is achieved by integrating multiple XPUs on the same interposer substrate. It is expected that performance can scale further by replacing the electrical interface with an optical variant. In this paper, we study the thermal challenges this concept brings for Si photonic disk modulators, a key component of the optical transceiver. Because of the highly integrated nature of the system, thermal crosstalk is especially a concern, as well as heater efficiency for thermal tuning. Detailed, experimentally calibrated simulations reveal a loss of heater efficiency between 42–62% after hybrid bonding of the electrical IC (EIC) on the photonic IC (PIC). This loss can partially be offset by introducing a new thermal isolation feature called TOPCUT, which blocks vertical heat conduction and increases efficiency by 25%. Alternatively, co-design of the EIC back-end-of-line layers and the PIC layout to ensure low metal density directly above the device can be done to gain 12% heater efficiency. Thermal simulations of a fully populated interposer wafer reveal extremely low thermal crosstalk between tiles, but significant crosstalk inside a single tile. Studies predict a spatial gradient of 12 K/mm and temporal gradient of 1.78 K/ms in the PIC due to XPU power map.
晶圆上系统高性能计算系统的最新发展为缓解AI/ML训练工作负载中遇到的内存墙提供了有希望的结果。这是通过在同一中间层基板上集成多个xpu来实现的。预计通过用光学变体取代电接口,性能可以进一步扩展。在本文中,我们研究了这一概念给光收发器的关键部件硅光子盘调制器带来的热挑战。由于系统的高度集成化,热串扰以及热调谐的加热器效率尤其值得关注。详细的、经过实验校准的模拟显示,电集成电路(EIC)在光子集成电路(PIC)上混合键合后,加热器效率损失在42-62%之间。通过引入一种名为TOPCUT的新型热隔离功能,可以部分抵消这种损失,该功能可以阻止垂直热传导,并将效率提高25%。或者,EIC后端线层和PIC布局的共同设计,以确保器件正上方的低金属密度,可以获得12%的加热器效率。对完全填充的中间层晶圆的热模拟显示,瓦片之间的热串扰极低,但单个瓦片内部的串扰显著。研究预测,由于XPU功率图,PIC的空间梯度为12 K/mm,时间梯度为1.78 K/ms。
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引用次数: 0
Assessment of Tartrazine Diffusion Properties in Skeletal Muscle 酒黄石在骨骼肌中的扩散特性评估
IF 5.1 2区 工程技术 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-12-08 DOI: 10.1109/JSTQE.2025.3640959
Ana R. Guerra;Luís R. Oliveira;Gonçalo O. Rodrigues;Maria R. Pinheiro;Maria I. Carvalho;Valery V. Tuchin;Luís M. Oliveira
Evaluating diffusion properties of novel optical clearing (OC) agents is critical for advancing medical imaging. Tartrazine (TTZ), a strong absorbing dye, has shown promise in enhancing tissue transparency, yet its diffusion properties remain uncharacterized. In this work, OC treatments with TTZ-water solutions with varying osmolarities were performed, and the diffusion times (τ) that characterize the tissue dehydration and the RI matching mechanisms were estimated. From kinetic Tc measurements during treatment, τ values of water and TTZ were estimated in muscles as 60.0 s and 416.0 s, respectively. Corresponding diffusion coefficients (D) were derived from sample thickness data measured during treatments where the unique fluxes of TTZ and water occur. The respective D values were then calculated as 1.9 × 10−6 cm2/s for water and 3.6 × 10−7 cm2/s for TTZ. These findings provide key insights into TTZ diffusion in skeletal muscle and support its potential as an effective OC agent.
评估新型光学清除剂(OC)的扩散特性对推进医学成像至关重要。酒黄石(TTZ)是一种强吸收染料,在提高组织透明度方面表现出了希望,但其扩散特性仍未被表征。在这项工作中,使用不同渗透压的ttz -水溶液进行OC处理,并估计表征组织脱水的扩散时间(τ)和RI匹配机制。从处理期间的动力学Tc测量中,估计肌肉中水和TTZ的τ值分别为60.0 s和416.0 s。相应的扩散系数(D)由在TTZ和水发生独特通量的处理期间测量的样品厚度数据得出。然后分别计算出水的D值为1.9 × 10−6 cm2/s, TTZ的D值为3.6 × 10−7 cm2/s。这些发现为TTZ在骨骼肌中的扩散提供了关键见解,并支持其作为有效OC剂的潜力。
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引用次数: 0
High-Efficiency Compact Optical Transmitter With a Total Bit Energy of 0.78 pJ/Bit Including Silicon Slow-Light Modulator and Open-Collector Current-Mode Driver 一种总比特能量为0.78 pJ/Bit的高效紧凑型光发射机,包括硅慢光调制器和开路集电极电流模式驱动器
IF 5.1 2区 工程技术 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-12-05 DOI: 10.1109/JSTQE.2025.3640645
Keisuke Kawahara;Tai Tsuchizawa;Noritsugu Yamamoto;Yuriko Maegami;Koji Yamada;Shinsuke Hara;Toshihiko Baba
Increasing datacenter demands require power-efficient optical interconnects. However, a conventional standard transmitter using a silicon rib-waveguide Mach-Zehnder modulator and voltage-mode driver has low efficiency and consumes watt-class high power and occupies a several-square-millimeter footprint, which limits large-scale integration for parallel transmission. This paper presents a transmitter consisting of a compact photonic crystal waveguide (PCW) modulator and a current-mode open-collector driver. The PCW modulator is designed to have high impedance in addition to the slow-light effect. The driver connected to the modulator without termination resistors is optimized based on electronics-photonics co-simulations using a standard electronic circuit simulator with an in-house photonic model library. Co-packaging these dramatically reduces the power consumption to 50 mW and a bit energy to 0.78 pJ/bit at 64-Gbaud, and the footprint to 0.66 mm2. This result represents a significant advancement toward the integration of a large number of transmission channels with no temperature control.
日益增长的数据中心需求需要高能效的光互连。然而,使用硅肋波导马赫-曾德尔调制器和电压模式驱动器的传统标准发射机效率低,消耗瓦级高功率,占用几平方毫米的占地面积,这限制了大规模集成并行传输。本文介绍了一种由紧凑型光子晶体波导(PCW)调制器和电流型开路集电极驱动器组成的发射机。PCW调制器除了具有慢光效应外,还具有高阻抗。利用标准的电子电路模拟器和内部的光子模型库,基于电子-光子学联合仿真,优化了无终端电阻连接到调制器的驱动器。这些共同封装显着降低了功耗至50 mW, 64-Gbaud时的比特能量降至0.78 pJ/bit,占地面积降至0.66 mm2。这一结果代表了在集成大量无温度控制传输通道方面取得的重大进展。
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引用次数: 0
Terahertz Chip-Scale Meta-Networks With LSPR Routing: A Theoretical Framework 具有LSPR路由的太赫兹芯片级元网络:一个理论框架
IF 5.1 2区 工程技术 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-12-03 DOI: 10.1109/JSTQE.2025.3639965
Maryam Khodadadi;Hamidreza Taghvaee;Pei Xiao;Gabriele Gradoni;Mohsen Khalily
Efficient chip-scale interconnects are critical for modern microelectronic–photonic systems, enabling high-bandwidth utilisation and ultra-low-latency processing. Conventional wired links suffer from high resistivity and latency, while radio-frequency and millimetre-wave wireless solutions face limitations such as bandwidth congestion, interference and power inefficiency. Terahertz (THz) plasmonic communication, utilising surface-plasmon polaritons (SPPs), is shown to provide broad bandwidth and high data rates for wireless network-on-chip (WiNoC) links, while remaining compatible with nanophotonic architectures. A novel Binary Field-Driven Meta-Routing Method is proposed, supported by a semi-analytical framework that models the interaction between graphene’s tunable electromagnetic properties and THz plasmonic phenomena. Graphene impedance modulation is exploited to dynamically couple localized surface-plasmon resonances (LSPRs) and guide them across a meta-network, enabling controlled beam steering within chip-scale architectures. Analytical conductivity models are combined with coupled-mode theory and algorithmic control to predict and configure LSPR-based beam steering in graphene metasurfaces. Four reconfigurable graphene meta-pixel antenna configurations — Y-MetaRouter, MetaSwitcher, Penta-MetaEmitter and CP-MetaCore — are designed and analysed; they enable unidirectional radiation, bi-directional meta-steering, frequency-driven multidirectional transitions and circular polarization, respectively. Real-time beam steering is enabled via chemical-potential modulation, thereby forming configurable LSPR pathways and creating virtual SPP channels. A theoretical formulation of the Coupled-Mode Theory of Field-Driven LSPR Meta-Networks is developed to model the current distribution of virtual SPPs and path-dependent LSPR coupling for prediction of far-field characteristics. Theoretical results show excellent agreement with full-wave numerical simulations. A point-to-point meta-wireless link is analysed by both theoretical and numerical methods, thereby demonstrating scalability for low-latency, high-performance THz communication in WiNoC and nanophotonic platforms. System-level metrics — such as link-budget, data-rate and reconfiguration energy — are estimated to validate feasibility for applications including chiplet communication, intra-core data transfer, heterogeneous computing, and compact transceivers in space-constrained environments.
高效的芯片级互连对于现代微电子-光子系统至关重要,可以实现高带宽利用率和超低延迟处理。传统的有线链路受到高电阻率和延迟的影响,而射频和毫米波无线解决方案则面临带宽拥塞、干扰和功率低效率等限制。利用表面等离子激元(SPPs)的太赫兹(THz)等离子通信被证明可以为无线片上网络(WiNoC)链路提供宽带和高数据速率,同时与纳米光子架构保持兼容。提出了一种新的二元场驱动的元路由方法,该方法由一个半解析框架支持,该框架模拟了石墨烯的可调谐电磁特性与太赫兹等离子体现象之间的相互作用。石墨烯阻抗调制被用于动态耦合局部表面等离子体共振(LSPRs),并引导它们穿过元网络,从而在芯片级架构中实现可控的光束导向。分析电导率模型与耦合模式理论和算法控制相结合,以预测和配置石墨烯超表面中基于lsr的光束转向。设计并分析了四种可重构的石墨烯元像素天线配置——Y-MetaRouter、MetaSwitcher、Penta-MetaEmitter和CP-MetaCore;它们分别实现了单向辐射、双向元转向、频率驱动的多向转换和圆极化。通过化学势调制实现实时波束控制,从而形成可配置的LSPR路径并创建虚拟SPP通道。建立了场驱动LSPR元网络的耦合模式理论,用于模拟虚拟spp的电流分布和路径依赖的LSPR耦合,用于预测远场特性。理论结果与全波数值模拟结果吻合良好。通过理论和数值方法分析了点对点元无线链路,从而证明了在WiNoC和纳米光子平台上低延迟、高性能太赫兹通信的可扩展性。系统级指标——如链路预算、数据速率和重新配置能量——估计用于验证应用的可行性,包括芯片通信、核心内数据传输、异构计算和空间受限环境中的紧凑型收发器。
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引用次数: 0
Dual Schottky Embedded Electronically Reconfigurable Toroidal Resonance 双肖特基嵌入式电子可重构环形共振
IF 5.1 2区 工程技术 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-12-03 DOI: 10.1109/JSTQE.2025.3639774
Nityananda Acharyya;Atul C. Khot;Shreeya H. Rane;Mangababu Akkanaboina;Soumyajyoti Mallick;Yogitha S N;Priyanka A;J.J. Heremans;Dhanvir Singh Rana;Tae Geun Kim;Dibakar Roy Chowdhury
Resonance phenomena play a crucial role in realizing intense light-matter interactions. However, in most resonance driven interactions radiative losses play a spoiling role. In this regard, toroidal resonance offers great promise to realize non-radiating charge current distributions leading to intense electromagnetic field confinements, ultimately negating the radiative losses. However, for real time photonic devices, electronically tunable toroidal modes are fundamental necessity. Hence, we demonstrate electrically tunable dual Schottky embedded toroidal metasurfaces operating in the terahertz (THz) regime. Platinum and aluminium metals on IGZO film simultaneously form the metal resonators for plasmonic metasurface as well as dual asymmetric Schottky contacts in a compact configuration. Such dual Schottky design allows electronically tunable metasurfaces operating in forward and reverse biases which is not feasible with a typical single Schottky contact. Further, our experiments demonstrate relative changes in toroidal mode, ∼19% for 18 V bias which is validated by an analytically derived multipole analysis. Moreover, the experimentally observed resonance modifications are qualitatively explained using voltage controlled Schottky depletion widths established underneath the metasurface resonators. Hence, this work showcases the potential of dual Schottky junctions in realizing electronically controlled compact metasurfaces that can be helpful in implementing miniaturized on-chip THz devices.
共振现象在实现强光-物质相互作用中起着至关重要的作用。然而,在大多数共振驱动的相互作用中,辐射损耗起着破坏作用。在这方面,环形共振为实现非辐射电荷电流分布提供了很大的希望,从而导致强烈的电磁场限制,最终消除辐射损失。然而,对于实时光子器件来说,电子可调谐的环面模式是必不可少的。因此,我们展示了在太赫兹(THz)区域工作的电可调谐双肖特基嵌入环面超表面。IGZO薄膜上的铂和铝金属同时形成等离子体超表面的金属谐振器以及紧凑结构的双非对称肖特基触点。这种双肖特基设计允许电子可调谐的元表面在正向和反向偏置中运行,这是典型的单肖特基接触不可行的。此外,我们的实验证明了环面模式的相对变化,18 V偏置约19%,这是通过解析推导的多极分析验证的。此外,实验观察到的共振变化是定性解释使用电压控制肖特基耗尽宽度下建立的超表面谐振器。因此,这项工作展示了双肖特基结在实现电子控制紧凑超表面方面的潜力,这有助于实现小型化的片上太赫兹器件。
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引用次数: 0
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IEEE Journal of Selected Topics in Quantum Electronics
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