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Dynamics of Asynchronous Dichromatic Dissipative Solitons in a GHz-Repetition-Rate Mode-Locked Fiber Laser ghz重复速率锁模光纤激光器中异步二色耗散孤子的动力学
IF 5.1 2区 工程技术 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-10-23 DOI: 10.1109/JSTQE.2025.3624360
Lin Ling;Yang Yang;Wei Lin;Zhaoheng Liang;Xuewen Chen;Xiaoming Wei;Zhongmin Yang
The generation of asynchronous dichromatic dissipative solitons (ADDSs) from a single laser cavity is a promising scheme for dual-comb spectroscopy, due to its compactness and robustness. Scaling the repetition rate of ADDSs to the GHz level holds the potential of improving the acquisition speed and spectral resolution of dual-comb spectroscopy, wherein it involves versatile soliton dynamics that may limit its performance. In this work, we study the buildup dynamics of ADDSs in an ultrashort fiber cavity that leverages multimode interference-induced spectral filtering effect, which enables dual-wavelength mode-locking at GHz. The buildup dynamics are experimentally captured in real time by using dispersive Fourier transform. The real-time observation reveals the asynchronous evolution of the dichromatic dissipative solitons. In a transitional stage, particularly, there present intense interaction and competition, accompanied by dynamic phenomena such as central wavelength shift, soliton explosions, and quasi-periodic pulsation. Our findings can provide deeper understanding on the formation of high-quality ADDSs.
从单一激光腔中产生异步二色耗散孤子(adds)由于其紧凑性和鲁棒性,是一种很有前途的双梳光谱方案。将adss的重复频率缩放到GHz水平有可能提高双梳光谱的采集速度和光谱分辨率,其中涉及到可能限制其性能的多种孤子动力学。在这项工作中,我们研究了利用多模干涉诱导的频谱滤波效应的超短光纤腔中ADDSs的积累动力学,从而实现了GHz双波长锁模。利用色散傅里叶变换,实验实时捕捉了累积动力学。实时观测揭示了二色耗散孤子的非同步演化。特别是在过渡阶段,存在着激烈的相互作用和竞争,并伴有中心波长移动、孤子爆炸和准周期脉动等动态现象。我们的研究结果可以为高质量adss的形成提供更深入的理解。
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引用次数: 0
Dynamic Control of Electromagnetically Induced Transparency in a Toroidal Planar Terahertz Metasurface 环面太赫兹超表面电磁感应透明的动态控制
IF 5.1 2区 工程技术 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-10-20 DOI: 10.1109/JSTQE.2025.3624107
Lavi Kumar Vaswani;Rohith K. M.;Bhagwat Singh Chouhan;Sirsendu Ghosal;Updesh Verma;Anuraj Panwar;P.K. Giri;Gagan Kumar
The dynamic control of terahertz (THz) transmission is crucial for next-generation devices, including sensors, modulators, and slow-light systems. This study investigates an actively tunable electromagnetically induced transparency (EIT) effect in a toroidal dipole-based THz metamaterial. Experimental and numerical analyses confirm toroidal excitation through surface current distributions, profiles of the magnetic field, and multipolar analysis. The metamaterials, fabricated on a flexible polyimide substrate, achieve tunable modulation of EIT using vanadium dioxide (VO$_{2}$). The terahertz time-domain spectroscopy in transmission mode reveals modulation efficiency of up to 50%. Additionally, active control of group delay is demonstrated, highlighting the versatility of the proposed design for advanced THz applications.
太赫兹(THz)传输的动态控制对下一代设备至关重要,包括传感器、调制器和慢光系统。本文研究了环面偶极子基太赫兹超材料中主动可调谐的电磁感应透明效应。通过表面电流分布、磁场分布和多极分析,实验和数值分析证实了环形激励。在柔性聚酰亚胺衬底上制备的超材料,利用二氧化钒(VO$_{2}$)实现了EIT的可调调制。传输模式下的太赫兹时域光谱显示调制效率高达50%。此外,还演示了群延迟的主动控制,突出了所提出的设计在高级太赫兹应用中的多功能性。
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引用次数: 0
Nanoparticle-Mediated Laser Ablation: An Integrated Phantom Experimental-Computational Framework for Selective Cancer Therapy 纳米粒子介导的激光消融:选择性癌症治疗的综合幻影实验-计算框架
IF 5.1 2区 工程技术 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-10-14 DOI: 10.1109/JSTQE.2025.3621353
Federica Bianconi;Elena De Vita;Brian Novati;Marco Giustra;Lucia Salvioni;Daniela Lo Presti;Filippo Testa;Carlo Massaroni;Agostino Iadicicco;Alessio Gizzi;Davide Prosperi;Emiliano Schena;Stefania Campopiano
Minimally invasive thermal ablation treatments (TATs) offer a promising alternative to conventional cancer therapies, delivering precision and reduced side effects. This study introduces an integrated approach to enhancing laser thermal ablation (LTA) by combining nanoparticle (NP) mediation, thermal monitoring, and advanced numerical modeling. Four types of gold based NPs, i.e., nanorods and nanocages with tunable optical properties, are experimentally tested in agarose-based phantoms to evaluate their effects on LTA technique at a wavelength of 1064 nm, showing potential to selectively enhance heat deposition within tumor tissues while protecting surrounding healthy structures. Laser irradiation was performed with a literature-consistent setting of 3 W power and 120 s of exposure time. These irradiation conditions are selected to reach cytotoxic temperatures while avoiding phantom degradation and allowed for properly showing the differences between NP formulations. Real-time temperature monitoring by Fiber Bragg Grating sensors (FBGs) ensured precise thermal control, with 34 sensors deployed in four arrays and positioned near the laser applicator, at a minimum distance of 2 mm from the laser tip, providing a temperature resolution of 0.1°C. Among the tested NPs, silver/gold nanocages with absorption maximum located at 816.9 nm exhibit the highest photothermal conversion efficiency. Meanwhile, advanced numerical modeling was employed, integrating the optical and thermal coupled processes, based on the optical diffusion approximation and the dual phase lag model, respectively. The model was refined with empirical data, validating and supporting the approach by predicting thermal mapping. This integrated framework shows promises for achieving selective and effective TAT, paving the way for selective cancer treatments.
微创热消融治疗(TATs)提供了一种有希望的替代传统癌症治疗方法,提供精度和减少副作用。本研究介绍了一种结合纳米颗粒(NP)中介、热监测和先进数值模拟的综合方法来增强激光热烧蚀(LTA)。四种类型的金基NPs,即具有可调光学性质的纳米棒和纳米笼,在琼脂糖基模型中进行了实验测试,以评估它们在1064 nm波长下对LTA技术的影响,显示出选择性增强肿瘤组织内热沉积的潜力,同时保护周围的健康结构。激光照射的设置与文献一致,功率为3w,曝光时间为120s。选择这些照射条件以达到细胞毒性温度,同时避免幽灵降解,并允许正确显示NP配方之间的差异。光纤布拉格光栅传感器(fbg)的实时温度监测确保了精确的热控制,34个传感器部署在四个阵列中,位于激光涂敷器附近,距离激光尖端最小2毫米,提供0.1°C的温度分辨率。其中,吸收最大值位于816.9 nm处的银/金纳米笼光热转换效率最高。同时,采用基于光学扩散近似和双相位滞后模型的先进数值模拟方法,将光学和热耦合过程整合在一起。利用经验数据对模型进行了改进,并通过预测热映射验证和支持了该方法。这一综合框架有望实现选择性和有效的TAT,为选择性癌症治疗铺平道路。
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引用次数: 0
Collagen-Related Information Facilitates the Stratification of Breast Cancer Patients With NHG2 胶原蛋白相关信息有助于乳腺癌患者NHG2的分层
IF 5.1 2区 工程技术 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-10-14 DOI: 10.1109/JSTQE.2025.3621506
Zhijun Li;Zhonghua Han;Shuoyu Xu;Gangqin Xi;Shunwu Xu;Jianhua Chen;Deyong Kang;Jianxin Chen
The Nottingham histological grade (NHG) is routinely used to stratify breast cancer patients into NHG1-3 for treatment decisions, yet NHG1/NHG2 ambiguity complicates personalized clinical strategy formulation. In this retrospective study, we included a total of 686 subjects. The NHG1 and 3 tumors (n = 204) in the training cohort (n = 424) were used to construct a tumor-associated collagen signatures-grade model (TACS-grade model) to leverage the difference in the 5-year DFS between NHG1 and NHG3, followed by re-stratifiy NHG2 tumors into TACS-grade 2(TG2)-low and TG2-high subtypes using the learned patterns. Model generalisability was further evaluated in the validation cohort (n = 262). Our results showed that the TG2-high had worse 5-year DFS than the TG2-low, and the 5-year DFS in TG2-high was 56.0% (54.3% in the validation cohort) and 78.8% in the TG2-low (75.0% in the validation cohort) in the training cohort. The 5-year DFS of TG2-low was similar to that of NHG1, while the 5-year DFS of TG2-high was similar to that of NHG3. After integrating the collagen-related information into the NHG system, the modified NHG system (MNHG) demonstrated superior prognostic discrimination. The TACS-grade model re-stratification of NHG2 tumors offers a cost-effective promise for tumor grading and thus may improve the accuracy of clinical decision-making.
诺丁汉组织学分级(NHG)通常用于将乳腺癌患者分为NHG1-3进行治疗决策,但NHG1/NHG2的不确定性使个性化临床策略的制定复杂化。在这项回顾性研究中,我们共纳入了686名受试者。训练队列(n = 424)中的NHG1和3肿瘤(n = 204)被用来构建肿瘤相关胶原蛋白特征分级模型(tacs分级模型),以利用NHG1和NHG3之间5年DFS的差异,随后使用学习模式将NHG2肿瘤重新分层为tacs - 2(TG2)低和TG2高亚型。在验证队列(n = 262)中进一步评估模型的通用性。我们的研究结果显示,tg2高组的5年DFS比tg2低组差,训练组tg2高组的5年DFS为56.0%(验证组为54.3%),tg2低组为78.8%(验证组为75.0%)。tg2低的5年DFS与NHG1相似,tg2高的5年DFS与NHG3相似。将胶原蛋白相关信息整合到NHG系统后,改进的NHG系统(MNHG)显示出更好的预后辨别能力。NHG2肿瘤的tacs级模型重新分层为肿瘤分级提供了一种具有成本效益的前景,从而可以提高临床决策的准确性。
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引用次数: 0
Biological Effects of Light-Emitting Diode (LED)-Based Low-Level Light on Natural Killer Cells 基于发光二极管(LED)的弱光对自然杀伤细胞的生物学效应
IF 5.1 2区 工程技术 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-10-09 DOI: 10.1109/JSTQE.2025.3619841
Hyun Bon Kang;Woo-Chang Son;Hong-Rae Lee;Eun-Kyoung Koh;Ga-Young Park;You-Soo Park
Natural killer (NK) cells have attracted considerable attention as a promising strategy for cancer immunotherapy, leading to research efforts aimed at enhancing their efficacy. However, despite the availability of various approaches to enhance NK cell function, there remains an urgent need for more efficient, cost-effective, and safe methods. Energy metabolism plays a critical role in the activation of NK cells. Low levels of light can influence cellular energy metabolism, thereby affecting cellular activity. In this study, we applied low-level light to human-derived NK-92 cells to investigate the changes in cellular activity induced by alterations in energy metabolism. Exposure to a 740 nm light-emitting diode (LED) at an energy density of 3 J/cm2 once daily for 3 consecutive days resulted in the most significant changes in adenosine triphosphate (ATP) levels. Furthermore, NK-92 cells produced ATP in a glycolysis-dependent manner, and exposure to 740 nm light further promoted the glycolytic process. Additionally, 740 nm light stimulation prevented apoptosis in cells and enhanced the cytotoxicity of NK-92 cells. In conclusion, these findings suggest that LED-based low level light therapy is a viable approach for enhancing the efficacy of NK cells.
自然杀伤(NK)细胞作为一种很有前途的癌症免疫治疗策略,引起了人们的广泛关注,人们致力于提高其疗效。然而,尽管有各种方法可以增强NK细胞的功能,但仍然迫切需要更有效、更经济、更安全的方法。能量代谢在NK细胞的激活中起着至关重要的作用。低水平的光照会影响细胞能量代谢,从而影响细胞活动。在这项研究中,我们将低强度光应用于人源性NK-92细胞,以研究能量代谢改变引起的细胞活性变化。在能量密度为3 J/cm2的740 nm发光二极管(LED)下连续暴露3天,导致三磷酸腺苷(ATP)水平发生最显著的变化。此外,NK-92细胞以糖酵解依赖的方式产生ATP,暴露于740 nm光下进一步促进糖酵解过程。740 nm光刺激可抑制NK-92细胞凋亡,增强细胞毒性。综上所述,这些发现表明基于led的弱光疗法是一种增强NK细胞功效的可行方法。
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引用次数: 0
Tunable Switching of Quasi-Bound States in the Continuum in Terahertz Metasurfaces 太赫兹超表面连续介质中准束缚态的可调谐开关
IF 5.1 2区 工程技术 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-10-08 DOI: 10.1109/JSTQE.2025.3619128
Jing Chen;Deguo Shi;Zongli Hu;Bin Tang
Bound states in the continuum (BIC) are a special type of optical resonance with strong field confinement and minimal energy loss, making them highly attractive for photonics applications. In this work, we propose a terahertz metasurface capable of supporting both symmetry-protected BIC and quasi-BIC (q-BIC) resonances. By intentionally breaking the structural symmetry, the optical response transitions from a symmetry-protected BIC to a leaky q-BIC resonance, enabling strong light-matter interaction. Especially, integrating the phase-change material vanadium dioxide (VO2) enables reversible, thermally driven switching between BIC and q-BIC modes via its insulator-to-metal transition. Meanwhile, a maximum modulation depth of 96% can be achieved by tuning the conductivity of VO2. Furthermore, the high quality-factor (Q-factor) of the q-BIC mode endows the hybrid metal-VO2 metasurface with remarkable sensing capabilities, achieving a sensitivity of 3708 GHz/RIU. This study advances the design of tunable terahertz devices, offering insights for dynamic modulators, switches, and high-performance sensors in the terahertz frequency range.
连续介质中的束缚态(BIC)是一种特殊类型的光学共振,具有强的场约束和最小的能量损失,使其在光子学应用中具有很高的吸引力。在这项工作中,我们提出了一种能够支持对称保护BIC和准BIC (q-BIC)共振的太赫兹超表面。通过故意破坏结构对称性,光学响应从对称保护的BIC转变为泄漏的q-BIC共振,从而实现强光-物质相互作用。特别是,集成相变材料二氧化钒(VO2)可以通过其绝缘体到金属的转变在BIC和q-BIC模式之间实现可逆的热驱动切换。同时,通过调节VO2的电导率,可以实现96%的最大调制深度。此外,q-BIC模式的高质量因子(Q-factor)赋予了混合金属- vo2元表面显著的传感能力,实现了3708 GHz/RIU的灵敏度。这项研究推进了可调谐太赫兹器件的设计,为太赫兹频率范围内的动态调制器、开关和高性能传感器提供了见解。
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引用次数: 0
Call for Papers: Special issue on Advances in Multifunctional Optical Spectrometers 征文:多功能分光计进展特刊
IF 5.1 2区 工程技术 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-10-08 DOI: 10.1109/JSTQE.2025.3615368
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引用次数: 0
Polarization Control and TM-Pass Filtering in SiN Photonics Integrated With 2D Multiferroic Materials 二维多铁性材料集成SiN光子学中的偏振控制和tm通滤波
IF 5.1 2区 工程技术 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-10-08 DOI: 10.1109/JSTQE.2025.3619201
Ghada Dushaq;Solomon Serunjogi;Srinivasa R. Tamalampudi;Mahmoud Rasras
Polarization control is a critical function in integrated photonic circuits, directly impacting performance, stability, and signal integrity. In this work, we demonstrate the integration of multiferroic two-dimensional (2D) material CuCrP2S6 (CCPS) with silicon nitride (SiN) photonic devices to achieve polarization-selective filtering and rotation. Our experimental results show that microring resonators incorporating CCPS exhibit transverse magnetic (TM)-pass filtering with a polarization extinction ratio exceeding 25 dB and a low insertion loss of ∼ 0.2–0.4 dB at 1500 −1600 nm. Additionally, under TM-mode input, straight waveguides loaded with CCPS can achieve a significant polarization rotation, with azimuth angle shifts reaching up to 92.9°. Simulations and experimental validation indicate that the primary mechanism behind these effects is the polarization-dependent optical mode overlap. This overlap is governed by the refractive index profile of the CCPS/SiN hybrid system and the waveguide’s geometrical dimensions. The anisotropic properties of CCPS provide further enhancement but play a secondary role. These results highlight the potential of CCPS-integrated devices for compact, high-performance polarization control in on-chip photonic platforms.
极化控制是集成光子电路的一个关键功能,直接影响到集成光子电路的性能、稳定性和信号完整性。在这项工作中,我们展示了多铁性二维(2D)材料CuCrP2S6 (CCPS)与氮化硅(SiN)光子器件的集成,以实现偏振选择性滤波和旋转。实验结果表明,采用CCPS的微环谐振器在1500 ~ 1600 nm处具有横向磁通滤波,极化消光比超过25 dB,插入损耗低至0.2 ~ 0.4 dB。此外,在tm模式输入下,加载CCPS的直波导可以实现显著的偏振旋转,方位角位移达到92.9°。模拟和实验验证表明,这些效应背后的主要机制是偏振相关的光学模式重叠。这种重叠是由CCPS/SiN混合系统的折射率分布和波导的几何尺寸决定的。CCPS的各向异性特性提供了进一步的增强,但起次要作用。这些结果突出了ccps集成器件在片上光子平台中实现紧凑、高性能偏振控制的潜力。
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引用次数: 0
Planar Tandem APD Array for Free Space Laser Communications Applications 用于自由空间激光通信的平面串联APD阵列
IF 5.1 2区 工程技术 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-10-03 DOI: 10.1109/JSTQE.2025.3617509
Pei-Syuan Lin;Kai-Ping Wang;Chao-Chuan Kuo;Hong-Sung Liao;You-Chia Chang;Jin-Wei Shi
Enlarging the active window size of the photodetector (PD) while sustaining its high-speed and high-responsivity performances is the key to achieving a high-performance photo-receiver with a large field-of-view (FoV) angle for application in a free space laser communication system. However, in the traditional PD structure, a large active area always leads to a pronounced degradation in the RC-bandwidth. Using a tandem layout for high-speed p-i-n PD arrays solves the problem, but it reduces the responsivity for high-speed and large FoV performance, as current balancing between the different p-n junctions is needed. Here, for the first time, novel tandem APD arrays are demonstrated which relax the fundamental trade-offs among window size, responsivity, and speed. Our flip-chip packaged 3 $ times $ 3 arrays with a window size of 0.12 mm can simultaneously achieve a, high-responsivity (1.2 A/W), wide-bandwidth (6 GHz), and large GBP (150 GHz).
扩大光电探测器(PD)的有效窗口尺寸,同时保持其高速和高响应性能是实现大视场角高性能光接收机应用于自由空间激光通信系统的关键。然而,在传统的PD结构中,较大的有源面积总是导致rc带宽的明显下降。使用串联布局的高速p-i-n PD阵列解决了这个问题,但它降低了高速和大视场性能的响应性,因为需要在不同的p-n结之间进行电流平衡。本文首次展示了新型串联APD阵列,该阵列放松了窗口大小、响应性和速度之间的基本权衡。我们的倒装芯片封装3 $ times $ 3阵列,窗口尺寸为0.12 mm,可以同时实现高响应(1.2 a /W)、宽带(6 GHz)和大GBP (150 GHz)。
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引用次数: 0
Optical Fiber Amplifiers for Satellite Communications 卫星通信用光纤放大器
IF 5.1 2区 工程技术 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-10-01 DOI: 10.1109/JSTQE.2025.3616785
Keith G. Petrillo;Justin Cook;Doruk Engin;Alex Sincore;Andrew M. Schober
Optical fiber amplifiers are crucial components for medium to long range space-based optical telecommunications networks. Current systems leverage technologies from the mature terrestrial optical fiber communications industry to enable rapid development and deployment of optical links and networks. However, link dynamics, performance metrics, and environmental conditions deviate significantly from terrestrial fiber telecommunications conditions and can vary depending on the orbit. This work reviews some of the major differences between optical fiber telecommunications and satellite free-space optical communications in the context of amplifier design and presents several examples of optical amplifiers developed to support space-based networks in both on-orbit and ground station applications. We discuss differences in the waveforms, link dynamics, and environmental conditions relevant to different space-based implementations. We also describe differences between multiple amplifier types, such as ground-based booster amplifiers and low noise optical receivers as well as amplifiers designed for various space orbital altitudes. Results and demonstrations show tremendous scalability and tailorability, exemplified in amplifiers from both CubeSat compatible compact and low-power models to larger long-range amplifiers with electrical to optical efficiencies up to 20% in the 1550 nm band.
光纤放大器是中远程天基光通信网络的关键部件。目前的系统利用成熟的地面光纤通信行业的技术,实现光链路和网络的快速开发和部署。然而,链路动态、性能指标和环境条件明显偏离地面光纤通信条件,并可能因轨道而异。这项工作回顾了光纤通信和卫星自由空间光通信在放大器设计方面的一些主要区别,并介绍了为支持在轨和地面站应用的天基网络而开发的光放大器的几个例子。我们讨论了与不同的空间实现相关的波形、链路动力学和环境条件的差异。我们还描述了多种放大器类型之间的差异,例如地基助推器放大器和低噪声光学接收器以及为各种空间轨道高度设计的放大器。结果和演示显示了巨大的可扩展性和可定制性,例如从CubeSat兼容的紧凑型和低功耗型号到更大的远程放大器,其电光效率在1550nm波段高达20%。
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引用次数: 0
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IEEE Journal of Selected Topics in Quantum Electronics
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