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Volatile organic compounds in carpet manufacturing plants: Exposure levels and probabilistic risk assessment using Monte-Carlo simulations 地毯制造工厂中的挥发性有机化合物:使用蒙特卡罗模拟的暴露水平和概率风险评估
Pub Date : 2022-08-21 DOI: 10.1080/10807039.2022.2112507
A. Khoshakhlagh, S. Morais
Abstract Air pollution due to volatile organic compounds (VOCs) in the workplace has been identified as a global problem. Therefore, the present study was conducted to assess the levels and the risk of occupational exposure of workers to benzene, toluene, ethylbenzene, and xylene (BTEX) in carpet manufacturing plants. BTEX sampling in the workers’ breathing zones was performed according to occupational safety and health standard methods using a personal sampling pump and analyzed by gas chromatography with flame ionization detection. The concentrations of all compounds were lower than the occupational exposure limits. However, the estimated lifetime cancer risks and the values of hazard quotient (95th percentile) for benzene and ethylbenzene suggest potential carcinogenic (2.97 additional cases per 10,000 employees exposed and 1.48 additional cases per 1,000 employees exposed) and non-carcinogenic (11.3–5.46 times greater than threshold risk level set by the US EPA) risks. Moreover, on the basis of the sensitivity analysis carried out using the Monte-Carlo simulation method, the concentration is the main parameter affecting significantly both cancer and non-cancer risks. This study is the first effort to provide information on health risk assessment of BTEX in the breathing zone of the employees in carpet manufacturing plants in the world and may be useful for potential plans of health risk management and reduction.
工作场所挥发性有机化合物(VOCs)引起的空气污染已被认为是一个全球性问题。因此,本研究旨在评估地毯制造工厂工人对苯、甲苯、乙苯和二甲苯(BTEX)的职业暴露水平和风险。按照职业安全卫生标准方法,使用个人采样泵对工人呼吸区BTEX进行采样,并采用气相色谱-火焰电离检测法进行分析。所有化合物的浓度均低于职业暴露限值。然而,苯和乙苯的估计终身癌症风险和危害商值(第95百分位数)表明潜在的致癌风险(每10,000名暴露的员工中有2.97例额外病例,每1,000名暴露的员工中有1.48例额外病例)和非致癌风险(比美国环保署设定的阈值风险水平高11.3-5.46倍)。此外,根据蒙特卡罗模拟方法进行的敏感性分析,浓度是影响癌症和非癌症风险的主要参数。本研究在国际上首次提供了地毯生产车间员工呼吸区BTEX的健康风险评估信息,可为制定健康风险管理和降低计划提供参考。
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引用次数: 5
Inhalation health risk assessment of ambient PM2.5 and associated trace elements in Cape Town, South Africa 南非开普敦环境PM2.5及相关微量元素的吸入健康风险评估
Pub Date : 2022-08-18 DOI: 10.1080/10807039.2022.2110449
Anna Alfeus, Péter Molnár, J. Boman, J. Shirinde, J. Wichmann
Abstract Few human health risk assessment studies of air pollution exist in Africa. This study used the US EPA health risk framework to investigate the human health risks due to inhalation exposure to ambient PM2.5 and some of its trace element composition (Cl, Si, and Ti) in Cape Town, South Africa, for 12 months (April 2017 to April 2018). The safe average daily dose was determined using the yearly WHO guideline and South African ambient air quality standard for PM2.5 and the US EPA regional screening levels for trace elements. The average yearly PM2.5 concentration (13 µg/m3) was above the yearly WHO guideline (5 µg/m3), but below the yearly South African standard (20 µg/m3). The average yearly PM2.5 concentration posed a low risk to adults (Hazard Quotient = 0.66) compared to infants (HQ = 2.13) and children (HQ =1.96). Cl posed health risks to all age groups (HQ > 1). The study concludes that PM2.5 and its trace element components pose adverse health effects to all population age groups. The toxicity of PM2.5 depends on its composition; hence this study recommends a source apportionment study to quantify the source contributions and inform the right abatement strategies.
非洲的空气污染人类健康风险评估研究很少。本研究使用美国环保署健康风险框架,调查了南非开普敦吸入暴露于环境PM2.5及其一些微量元素组成(Cl, Si和Ti)的人类健康风险,为期12个月(2017年4月至2018年4月)。安全平均日剂量是根据世卫组织年度指南和南非PM2.5环境空气质量标准以及美国环保署微量元素区域筛查水平确定的。年平均PM2.5浓度(13µg/m3)高于世卫组织年度指南(5µg/m3),但低于南非年度标准(20µg/m3)。与婴儿(HQ = 2.13)和儿童(HQ =1.96)相比,年平均PM2.5浓度对成人(危险系数= 0.66)构成的风险较低。PM2.5及其微量元素对各年龄段人群均存在健康风险(HQ > 1)。研究认为PM2.5及其微量元素对各年龄段人群均存在健康危害。PM2.5的毒性取决于其成分;因此,本研究建议进行来源分配研究,以量化来源贡献并告知正确的减排策略。
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引用次数: 1
Groundwater quality evaluation using water quality index (WQI) and human health risk (HHR) assessment in Herat aquifer, west Afghanistan 利用水质指数(WQI)和人类健康风险(HHR)评价阿富汗西部赫拉特含水层地下水质量
Pub Date : 2022-08-09 DOI: 10.1080/10807039.2022.2075316
A. Shakeri, Hashim Hosseini, M. Rastegari Mehr, M. Dashti Barmaki
Abstract Numerous political and economic crises, and successive wars in Afghanistan have put safe water resources at risk due to mismanagement in the country. In this study, groundwater quality in the Herat aquifer, western Afghanistan is evaluated by geochemical methods and quality indices. Total of 27 samples were collected and analyzed for nitrate, fluoride and trace elements. Sodium and bicarbonate are the main cation and anion, respectively. Various diagrams revealed that rock weathering and normal ion exchange may controls the major ion chemistry. Granitic or biotite gneiss rocks and leachate from the Herat urban sewage are the main sources of fluoride and nitrate, respectively. Geogenic source of the studied parameters was verified by principal component analysis (PCA). Groundwater is contaminated by F, As and U in the Northwest of the region, and by nitrate almost in the majority of samples, especially in urban areas. Water quality index (WQI) showed poor quality for 29.6% of the samples, and the best quality was observed in Southwest of the area. Also, based on heavy metal evaluation index (HEI), the highest pollution was observed in Northwestern region. Nitrate poses a serious health risk to consumers (particularly in central parts), so that non-carcinogenic risk (HQ) values ranged from 1.1 to 3 in most of the samples, and very high (> 3) non-carcinogenic risk values were observed in 4 sampling sites.
由于阿富汗的管理不善,无数的政治和经济危机以及连续的战争使安全的水资源处于危险之中。本研究采用地球化学方法和水质指标对阿富汗西部赫拉特含水层的地下水水质进行了评价。共采集27份样品进行硝酸盐、氟化物和微量元素分析。钠和碳酸氢盐分别是主要的阳离子和阴离子。各种图表显示,岩石风化和正常的离子交换可能控制了主要的离子化学。花岗岩或黑云母片麻岩和赫拉特城市污水的渗滤液分别是氟化物和硝酸盐的主要来源。通过主成分分析(PCA)对研究参数的地质来源进行了验证。该地区西北部地下水受F、As和U污染,大部分样本受硝酸盐污染,城市地区尤甚。水质指数(WQI)为差的样品占29.6%,其中西南水质最好。重金属污染评价指数(HEI)显示西北地区污染最严重。硝酸盐对消费者构成严重的健康风险(特别是在中部地区),因此大多数样品的非致癌风险(HQ)值在1.1至3之间,在4个采样点观察到非常高(>.3)的非致癌风险值。
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引用次数: 7
Assessing vulnerability of coupled human–environment systems and its influence factors in Yan'an City, China 延安市人-环境耦合系统脆弱性评价及其影响因素
Pub Date : 2022-08-09 DOI: 10.1080/10807039.2022.2093156
Guowei Nan, Lei Han, Yueyue Wang
Abstract The natural, economic, social, resource and other factors were incorporated into the framework of VSD model, and vulnerability and obstacle degree models were used to analyze the spatio-temporal evolution and influencing factors of coupled human–environment system in Yan'an City. The results show that: (1) The overall vulnerability of coupled human–environment systems in Yan'an city from 2000 to 2014 is between 0.2589 and 17.0180, the vulnerability index values of counties in the northwest and northeast are higher, while those in the central and southern regions are lower. (2) The spatial variability in exposure (0.1516–0.2255), sensitivity (0.2235–0.3093), adaptive capacity (0.6588–0.8865) and vulnerability (0.7502–0.7949) in the study area from 2000 to 2014 showed a downward trend. The spatial variability in exposure and sensitivity in each period was moderate, while adaptive capacity and vulnerability displayed strong variability. (3) There are significant differences in the obstacles affecting vulnerability in the study area. Unreasonable economic structure, fragile ecological environment, low level of economic and social development and low efficiency of production are the leading factors affecting the sustainability of coupled human–environment system, which means that how to adjust the economic structure and improve the ecological environment is the key to the sustainable development of resource-based cities.
摘要将自然、经济、社会、资源等因素纳入VSD模型框架,采用脆弱性和障碍度模型分析延安市人-环境耦合系统的时空演变及其影响因素。结果表明:(1)2000 - 2014年延安市人-环境耦合系统总体脆弱性介于0.2589 ~ 17.0180之间,西北和东北区县脆弱性指数较高,中部和南部区县脆弱性指数较低;(2) 2000 - 2014年研究区暴露度(0.1516 ~ 0.2255)、敏感性(0.2235 ~ 0.3093)、适应能力(0.6588 ~ 0.8865)和脆弱性(0.7502 ~ 0.7949)的空间变异性呈下降趋势。各时期暴露度和敏感性的空间变异性均为中等,而适应能力和脆弱性的空间变异性较强。(3)研究区影响脆弱性的障碍存在显著差异。经济结构不合理、生态环境脆弱、经济社会发展水平低下和生产效率低下是影响人-环境耦合系统可持续性的主导因素,如何调整经济结构和改善生态环境是资源型城市可持续发展的关键。
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引用次数: 1
Urinary brominated trihalomethanes among pregnant women: Correlation with lifestyle factors 孕妇尿中溴化三卤甲烷:与生活方式因素的相关性
Pub Date : 2022-08-05 DOI: 10.1080/10807039.2022.2107479
Bahare Dehdashti, A. Feizi, A. Arvin, N. Bagheri, Seyede Shahrbanoo Daniali, M. Amin, R. Kelishadi
Abstract According to the epidemiological evidences, long-term exposure to trihalomethanes containing bromine (Br-THMs) is associated with a variety of unpleasant consequences such as congenital malformations, preterm delivery, changing in gestational age, fetal growth and death, etc. The objective of current work was to monitor Br-THMs concentration in the pregnant women’s urine samples, to understand relationship between Br-THMs concentration and sociodemographic and water-use behavior as lifestyle factors. In this study, 118 third-trimester pregnant women, who cooperated in the Persian Birth Cohort, were studied. The concentration distribution of urine samples that were measured by a gas chromatography-mass spectrometer (GC-MC) had a positive deviation that was exposed to logarithmic transformation. By utilization of independent samples of t test, one-way ANOVA, Spearman ranks correlation coefficient, and multivariable linear regression, relationship between Br-THMs concentrations of urine with demographic and lifestyle factors was evaluated. According to the results, mean concentrations (standard deviation) of Br-THMs including bromodichloromethane (BDCM), dibromochloromethane (DBCM), and total bromoform (TBM) were recorded as 30.17 (40.80), 10.25 (11.37), 14.76 (27.17), and 4.96 (3.21) ng/L, respectively. The regression model predicted significant increase in relationship between time of washing clothes by hand and the concentration of Br-THMs. In the analysis of the relationship between using storage tanks as a source of drinking water and the contaminants, according to different statistical methods, inverse meaningful correlation relationship was found.
根据流行病学证据,长期接触含溴三卤甲烷(Br-THMs)可导致先天性畸形、早产、胎龄改变、胎儿生长和死亡等不良后果。本研究的目的是监测孕妇尿液样本中溴三thms浓度,了解溴四thms浓度与社会人口统计学和用水行为作为生活方式因素的关系。在本研究中,研究了118名晚期妊娠妇女,她们在波斯出生队列中合作。气相色谱-质谱仪(GC-MC)测定的尿样浓度分布存在正偏差,并对其进行对数变换。采用独立样本t检验、单因素方差分析、Spearman秩相关系数和多变量线性回归等方法,评价尿Br-THMs浓度与人口统计学和生活方式因素的关系。结果表明,含溴二氯甲烷(BDCM)、二溴氯甲烷(DBCM)和总溴仿(TBM)的Br-THMs平均浓度(标准差)分别为30.17(40.80)、10.25(11.37)、14.76(27.17)和4.96 (3.21)ng/L。回归模型预测手洗时间与Br-THMs浓度之间的关系显著增加。在分析储罐作为饮用水水源与污染物的关系时,根据不同的统计方法,发现了有意义的负相关关系。
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引用次数: 0
Health risk assessment using chemical signatures of fine and coarse particles collected at breathing level height during firework display in New Delhi, India 使用在印度新德里烟花表演期间在呼吸水平高度收集的细颗粒和粗颗粒的化学特征进行健康风险评估
Pub Date : 2022-08-03 DOI: 10.1080/10807039.2022.2107480
Amarjeet Rathee, S. Yadav
Abstract Sporadic emissions of fine (PM2.5) and coarse (PM2.5-10) particles at breathing level height (BLH) during Diwali, before Diwali and after Diwali (DD, BD and AD) in fireworks ban and no-ban years (2017 and 2018) were studied for water-soluble inorganic ions (WSII), organic and elemental carbon (OC and EC), metals and health risk. Average PM2.5 level at BLH exceeded Air Quality Standard (60 µgm−3) by 7.6, 3.7 and 3.2 times during BD, DD and AD, respectively, in 2017 while impulsive increase was observed in 2018 during DD (26 times) followed by AD and BD (5.2 and 4.7 times). Al, K, Sr, Ba, NO3 -, OC, Cl- in PM2.5 showed sudden increase during DD compared to BD and AD in non-Ban year (2018) and can be considered as markers of firework display. OC was more than EC in PM2.5 and was highest during BD and AD, as compare to DD. Dry deposition of emissions and re-suspension of residual ash/unburnt mass could be a reason for poor air quality at BLH. High Hazardous Index (HI) values in both size particles indicated that children were more vulnerable to exposure and were at high risk compared to adults. Cr followed by Cd and Ni in particles posed carcinogenic risk to children and adults. More such studies shall be conducted at BLH to improve human health risk assessment due to PM2.5 exposure.
摘要研究了2017年和2018年排灯节期间、排灯节前和排灯节后(DD、BD和AD)呼吸水平高度(BLH)细颗粒物(PM2.5)和粗颗粒物(PM2.5-10)的零星排放,以及禁放烟花年和禁放烟花年(2017年和2018年)的水溶性无机离子(WSII)、有机碳和元素碳(OC和EC)、金属和健康风险。在2017年的BD、DD和AD期间,BLH的平均PM2.5水平分别超过空气质量标准(60µgm - 3)的7.6倍、3.7倍和3.2倍,而在2018年的DD期间(26倍),其次是AD和BD(5.2倍和4.7倍),出现了脉冲增长。PM2.5中的Al、K、Sr、Ba、NO3 -、OC、Cl-在非ban年(2018年)DD期间比BD和AD期间突然增加,可以认为是烟花燃放的标志。PM2.5中的OC高于EC,在BD和AD期间最高,与DD相比。排放物的干沉积和残余灰/未燃烧物质的重新悬浮可能是BLH空气质量差的原因。两种大小颗粒的高危险指数(HI)值表明,与成人相比,儿童更容易受到暴露,处于高风险中。颗粒中的铬、镉和镍对儿童和成人具有致癌风险。卫生署应进行更多此类研究,以改善PM2.5暴露对人体健康的风险评估。
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引用次数: 3
Endocrine disrupting compounds (EDCs) in source water, finished water, and tap water from drinking water treatment plants and its human risk assessment in Chengdu Plain, China 成都平原饮用水处理厂源水、成品水和自来水中的内分泌干扰物(EDCs)及其对人体的风险评价
Pub Date : 2022-08-01 DOI: 10.1080/10807039.2022.2105195
Y. Jian, Xia Yunting, Tian Xianghong, Zhang Rong, Bian Zhanqiang
Abstract A study to monitor endocrine disrupting compounds (EDCs) [including pesticides, phthalate acid esters (PAEs), and polychlorinated biphenyls (PCBs)] in drinking water treatment plants from water source to consumers tap in Chengdu Plain was undertaken. A total of 37 source water, 37 finished water, and 37 tap water samples were collected during the period from July to August in 2021. Based on the survey results, a human health noncarcinogenic and carcinogenic risk assessment was conducted for adults and children. The results showed that the pesticides: atrazine, acetochlor, alachlor, heptachlor, and chlorpyrifos were detected in source, finished, and tap water, the detection rate of heptachlor was the highest in source (29.73%), finished (21.62%), and tap water (29.73%). Hexachlorobenzene and chlorothalonium were not detected in source, finished, and tap water. The concentrations of total PAEs ranged from not detected (nd)—1788.79 ng/L (median = 470.23 ng/L), nd to 3755.13 ng/L (median = 423 ng/L), and nd to 4095.89 ng/L (median = 585.12 ng/L) for source, finished, and tap water, respectively. The ΣPCBs were from nd to 239.65 ng/L (median = 91.03 ng/L), nd to 50.4 ng/L (median = 18.04 ng/L), and nd to 157.96 ng/L (median = 58.13 ng/L) for source, finished, and tap water, respectively. The hazard quotient (HQ) of EDCs in tap water of Chengdu Plain was lower than 1 and the highest value was 1.60E-02, which suggests that EDCs are considered unlikely to pose noncarcinogenic effects to individuals. Carcinogenic risk caused by EDCs for adults (both in median and highest concentration) was much lower than the 1.0E-04 cancer risk level, while the highest risk caused by EDCs for children through tap water was 9.48E-05.
摘要对成都平原自来水厂从水源地到消费者自来水口的内分泌干扰物(EDCs)(包括农药、邻苯二甲酸酯(PAEs)和多氯联苯(PCBs))进行了监测研究。在2021年7月至8月期间,共采集了37份水源水、37份成品水和37份自来水样本。根据调查结果,对成人和儿童进行了人类健康非致癌性和致癌性风险评估。结果表明:源、成品和自来水中检出莠去津、乙草胺、甲草胺、七氯胺和毒死蜱,其中源、成品和自来水中七氯胺的检出率最高,分别为29.73%、21.62%和29.73%;源、成品和自来水中未检出六氯苯和氯thalonium。源、成品和自来水的总PAEs浓度范围分别为未检出(nd) -1788.79 ng/L(中位数= 470.23 ng/L)、3755.13 ng/L(中位数= 423 ng/L)和4095.89 ng/L(中位数= 585.12 ng/L)。来源水、成品水和自来水的ΣPCBs分别为nd ~ 239.65 ng/L(中位数为91.03 ng/L)、nd ~ 50.4 ng/L(中位数为18.04 ng/L)和nd ~ 157.96 ng/L(中位数为58.13 ng/L)。成都平原自来水中EDCs的危害商数(HQ)均小于1,最高值为1.60E-02,认为EDCs不太可能对个体产生非致癌作用。EDCs对成人(中位浓度和最高浓度)的致癌风险均远低于1.0E-04的致癌风险水平,而自来水对儿童EDCs的致癌风险最高为9.48E-05。
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引用次数: 1
Hydrogeophysical characterization of the Southern Red Sea coastal aquifer, Saudi Arabia, using Time-Domain electromagnetic method 利用时域电磁法对沙特阿拉伯南红海沿岸含水层进行水文地球物理表征
Pub Date : 2022-07-27 DOI: 10.1080/10807039.2022.2104693
S. Qaysi, Salman S. Alharbi, Mahmoud M. Elwaheidi
Abstract The research aims to characterize the shallow coastal aquifer of the Red Sea in terms of lateral and vertical extensions and to determine the factors controlling the quality of groundwater using the Time-Domain Electromagnetic sounding method. The aquifer consists of alluvial sediments with an increasing thickness toward NE. Groundwater resistivity is variable from less than 5 Ω.m at the coastal strip to 20 Ω.m at 5 km toward NE. Furthermore, resistivity reached up to 100 Ω.m in other parts of the area. Variations in aquifer resistivity are attributed to lithological changes and seawater intrusion. Aquifer resistivity and the total dissolved solid values from wells indicate that the aquifer is adequate for agricultural usage except along the coastal areas.
摘要采用时域电磁测深方法对红海浅海含水层进行横向和纵向扩展特征描述,确定地下水质量控制因素。含水层由冲积沉积物组成,厚度向东北方向增加。地下水电阻率从小于5 Ω开始变化。M在沿海地带到20 Ω。风速5公里,向东北方向。电阻率高达100 Ω。在这个地区的其他地方。含水层电阻率的变化归因于岩性变化和海水侵入。含水层电阻率和井中总溶解固体值表明,除沿海地区外,该含水层适合农业使用。
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引用次数: 1
Temporal effect of phytoremediation on the bacterial community in petroleum-contaminated soil 植物修复对石油污染土壤细菌群落的时间效应
Pub Date : 2022-07-26 DOI: 10.1080/10807039.2022.2102460
Yuanyuan Shen, Yuchen Ji, Wenke Wang, Tianpeng Gao, Haijuan Li, Mingyan Xiao
Abstract Phytoremediation is a promising bio-technology where plants associated with microbes are employed to remediate sites co-contaminated with petroleum. With the in-depth study of plant restoration, it is necessary to explore the dynamic changes of microbial communities in petroleum-contaminated soil. This study investigated the effects of Ryegrass on bacterial community and diversity in petroleum contaminated soil. High-throughput sequencing technology was used to compare the bacterial communities in 14 groups samples at different repair stages. It was concluded that different responses were observed to promote or inhibit microbial reproduction. The most significant bacterial family were Comamonadaceae, Nocardiaceae, Blastocatellaceae, and Cytophagacea. Comamonadaceae showed the highest level of remediation in non-petroleum-contaminated soils at 90 days. However, Blastocatellaceae and Cytophagaceae exhibited high microbial contents in petroleum-contaminated soil at 0 and 40 days, respectively. In all samples, plants improved the remediation of petroleum-contaminated soil and the highest abundance of microbial communities were found after 90 days. These data indicate that not only rhizosphere secretions but also petroleum, will promote microbial growth. Moreover, the repair time has a vital effect on microbial community changes. This study supports the foundation to control soil pollution and highlight the periodic dynamic of microbial community diversity and structure.
摘要植物修复是一项很有前途的生物技术,利用植物与微生物结合对石油共污染场地进行修复。随着植物恢复研究的深入,有必要探讨石油污染土壤中微生物群落的动态变化。研究了黑麦草对石油污染土壤细菌群落和多样性的影响。采用高通量测序技术对14组样品在不同修复阶段的细菌群落进行比较。结果表明,在促进或抑制微生物繁殖方面存在不同的反应。其中最显著的细菌科为单胞菌科、诺卡菌科、芽孢菌科和细胞菌科。在非石油污染土壤中,绿藓科植物在90 d时的修复效果最高。而在石油污染土壤中,Blastocatellaceae和Cytophagaceae的微生物含量分别在0和40 d时较高。在所有样品中,植物都改善了石油污染土壤的修复,并且在90天后发现微生物群落的丰度最高。这些数据表明,除了根际分泌物外,石油也会促进微生物的生长。此外,修复时间对微生物群落的变化有重要影响。本研究为土壤污染治理奠定了基础,同时也凸显了微生物群落多样性和结构的周期性动态。
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引用次数: 0
Perfluoroalkyl and polyfluoroalkyl substances, bisphenol and paraben compounds in dust collected from residential homes in Klang Valley, Malaysia 从马来西亚巴生谷住宅收集的灰尘中的全氟烷基和多氟烷基物质、双酚和对羟基苯甲酸酯化合物
Pub Date : 2022-07-25 DOI: 10.1080/10807039.2022.2101429
D. E. Mohamad Haron, M. Yoneda, R. Hod, M. I. A. Wahab, M. Aziz
Abstract Endocrine disrupting chemicals (EDCs) are a growing global concern due to their widespread use and potential harm to human and animal health. Several EDCs have been linked to cancer, obesity, and diabetes in children and adults. EDCs come from manufacturers or everyday products like cookware, textile, cosmetic, furniture, and plastic. Some EDCs are volatile and may be inhaled by the inhabitants where indoor exposure to EDCs is considered worse than outdoor exposure due to the limited and confined area allowing dermal contact and ingestion of EDCs. During the COVID-19 pandemic in 2020–2021, all Malaysians were confined to their homes, prompting the goal of this study to investigate EDCs in household dust collected from Klang Valley homes. A total of 57 dust samples were collected, filtered, and extracted using methanol. EDCs including perfluoroalkyl and polyfluoroalkyl substances (PFAS), bisphenol and parabens were identified and quantified in dust samples by liquid chromatography mass tandem spectrometry (LCMS/MS). The presence of perfluorooctanoic acid (PFOA), perfluorooctane sulfonic acid (PFOS), butylparaben (BuP), methylparaben (MeP), ethylparaben (EtP), and propylparaben (PrP) was detected in 50–100% of dust samples, with range of concentration of 0.31–3693.96 ng/g, indicating that these compounds are common in indoor dust. Methylparaben was the most prevalent EDC in collected dust samples with mean concentration at 148. 18 ng/g, accounting for 54% of the concentration distribution, followed by BuP and PFOA. There were regional differences in EDC profiles, with higher PFAS and paraben levels in urban areas such as Putrajaya, Kuala Lumpur, and Petaling. The estimated daily intake (EDI) of EDCs from indoor dust ingestion varied by age, with infants having a significantly higher EDI (p < .01) than children and adults. Despite safe for consumption (Hazard Quotient, HQ < 1), these findings provide a baseline for assessing PFAS, bisphenol, and paraben in indoor dust from Malaysian homes.
摘要内分泌干扰物(EDCs)由于其广泛的使用和对人类和动物健康的潜在危害而日益受到全球的关注。一些EDCs与儿童和成人的癌症、肥胖和糖尿病有关。EDCs来自制造商或日常用品,如炊具、纺织品、化妆品、家具和塑料。有些EDCs是挥发性的,可能被居民吸入,而室内暴露于EDCs的情况被认为比室外暴露更严重,因为允许皮肤接触和摄入EDCs的区域有限。在2020-2021年COVID-19大流行期间,所有马来西亚人都被限制在家中,这促使本研究的目标是调查从巴生谷家庭收集的家庭灰尘中的EDCs。共收集了57个粉尘样品,过滤后用甲醇提取。采用液相色谱-质谱联用技术(LCMS/MS)对粉尘样品中的EDCs,包括全氟烷基和多氟烷基物质(PFAS)、双酚和对羟基苯甲酸酯进行了鉴定和定量。在50-100%的粉尘样品中检测到全氟辛酸(PFOA)、全氟辛烷磺酸(PFOS)、对羟基苯甲酸丁酯(BuP)、对羟基苯甲酸甲酯(MeP)、对羟基苯甲酸乙酯(EtP)和对羟基苯甲酸丙酯(PrP)的存在,浓度范围为0.31-3693.96 ng/g,表明这些化合物在室内粉尘中很常见。对羟基苯甲酸甲酯是采集的粉尘样品中最常见的EDC,平均浓度为148。18 ng/g,占浓度分布的54%,其次是BuP和PFOA。EDC分布存在区域差异,在布城、吉隆坡和佩打令等城市地区,PFAS和对羟基苯甲酸酯水平较高。室内灰尘摄入EDCs的估计每日摄入量(EDI)因年龄而异,婴儿的EDI显著高于儿童和成人(p < 0.01)。尽管食用是安全的(危害商数,HQ < 1),但这些发现为评估马来西亚家庭室内粉尘中的PFAS、双酚和对羟基苯甲酸酯提供了基线。
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Human and Ecological Risk Assessment: An International Journal
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