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An Emerging Infection “Scrub Typhus”– A Detailed Clinical Profile and Complications among Children in a Tertiary Hospital 一种新发感染“恙虫病”——某三级医院儿童的详细临床资料和并发症
Pub Date : 2023-01-01 DOI: 10.37506/ijphrd.v14i4.19831
Objectives: To study the clinical profile and complications of Scrub typhus in children.Methods: This descriptive study conducted in Siddhartha Medical college, Vijayawada, among children less than12 years for a period of one year(December 2020-November 2021).A total of 49 children who are serologically/clinically diagnosed cases of Scrub typhus.Results: Scrub typhus mainly occurred in school going children with male predominance. Fever being the singlemost clinical presentation in most of the cases(95.9%) associated with pallor, hepatosplenomegaly. Co infectionwas documented in 14.2% cases with 85.7% cases showing increased morbidity and mortality. Mortality rate ismore in infants.Conclusions: Among cases of Acute febrile illness, Scrub typhus accounts for 9.8% of cases. Main clinical featureswere persistent fever, hepatosplenomegaly, thrombocytopenia, anemia along with capillary leak signs like edemawith or without eschar.Infants are at high risk for complications and mortality.
目的:探讨小儿恙虫病的临床特点及并发症。方法:本描述性研究在维杰亚瓦达悉达多医学院进行,研究对象为12岁以下儿童,为期一年(2020年12月- 2021年11月)。共有49名儿童经血清学/临床诊断为恙虫病病例。结果:恙虫病以学龄儿童为主,以男性为主。发热是大多数病例(95.9%)的唯一临床表现,并伴有苍白、肝脾肿大。14.2%的病例有Co感染记录,85.7%的病例发病率和死亡率增加。婴儿死亡率更高。结论:在急性发热性疾病中,恙虫病占9.8%。主要临床表现为持续发热、肝脾肿大、血小板减少、贫血伴水肿或无结痂等毛细血管渗漏征象。婴儿出现并发症和死亡的风险很高。
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引用次数: 0
Demographic, Clinical and Etiological Profile of Children Admitted with Febrile Seizures in a Tertiary Care Hospital of North India 北印度一家三级医院收治的儿童热性惊厥的人口学、临床和病因学概况
Pub Date : 2023-01-01 DOI: 10.37506/ijphrd.v14i4.19767
This retrospective hospital-based study was conducted in Paediatric emergency from 1st June 2022 to 30th November2022 to study the clinical demographic and etiological profile of paediatric patients admitted with febrile seizures.Out of total enrolled 243 children, 153(63%) were male and 100(37%) were females. Mean age of the patients was23.5 months. Mean time interval between onset of fever and occurrence of seizures was 18 hours. Overall, 170(70%)patients had simple seizures. Only 85(35%) patients had positive family history and 73(30%) had recurrence ofseizures during the same episode of illness. Acute respiratory infection was the commonest cause for febrileseizure in 190(78%) children.
这项基于医院的回顾性研究于2022年6月1日至2022年11月30日在儿科急诊科进行,研究住院的儿科热性惊厥患者的临床人口统计学和病因学特征。在总共登记的243名儿童中,153名(63%)为男性,100名(37%)为女性。患者平均年龄23.5个月。发热至癫痫发作的平均时间间隔为18小时。总体而言,170例(70%)患者有单纯癫痫发作。仅有85例(35%)患者有阳性家族史,73例(30%)患者在同一发作期间有癫痫复发。急性呼吸道感染是190例(78%)儿童发热性惊厥的最常见原因。
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引用次数: 0
Prognostic Relevance of Serum Ferritin on Short Term and Long term Outcome In Patients With Acute Myocardial Infarction 血清铁蛋白与急性心肌梗死患者短期和长期预后的相关性
Pub Date : 2023-01-01 DOI: 10.37506/ijphrd.v14i2.20129
Objective-Over the decades coronary artery disease appears to be an emerging cause of mortality andmorbidity. Elevated serum ferritin as a risk factor for development of AMI. However its role with regard tooutcome and prognosis of AMI still remains a matter of debate. Hence, the present study was aimed toestimate the prognostic relevance of serum ferritin in relation to short term and long term survival outcomes inpatients with AMI.Methods- Out of a total number of 100 patients,with first AMI (50 of STEMI & 50 of NSTEMI diagnosis)admitted within 12 hours of the onset of chest pain to coronary care units at MKCG MedicalCollege&Hospital over a period of 1 year. Serum ferritin was measured using an ELISA assay by a special kit.The patients were divided into three groups according to Serum ferritin level.i.e.(1sttertile:<120 ng/ml,2ndtertile:120 to 220 ng/ml and 3rd tertile:>220 ng/ml).Baselinecharacteristics,LVEjection Fraction, Killipfunctional class and outcomes were compared among three different groups of serum ferritin.Results:There was a significant correlation between serum ferritin and LV ejection fraction(p=0.01),Killipclass(p=0.03) and mortality(p=0.03). Lower and higher levels of ferritin (1st and 3rd tertiles, ≤ 120; >220 ng/ml,respectively) were associated with a higher incidence of HF during hospitalization and death at 1 year.Conclusion:Raised serum ferritin is associated with worse short term and longterm outcome followingmyocardial infarction.
目的:在过去的几十年里,冠状动脉疾病似乎是一个新兴的死亡率和发病率的原因。血清铁蛋白升高是急性心肌梗死发生的危险因素。然而,它在AMI的预后和预后方面的作用仍然存在争议。因此,本研究旨在评估血清铁蛋白与AMI住院患者短期和长期生存结果的预后相关性。方法:在总共100例患者中,首次AMI (STEMI 50例);在1年的时间里,有50例(NSTEMI诊断)在胸痛发作后12小时内被送往MKCG医学院医院的冠状动脉护理部门。血清铁蛋白采用ELISA法测定,采用专用试剂盒。根据血清铁蛋白水平将患者分为3组(1组:120 ng/ml;2组:120 ~ 220 ng/ml; 3组:220 ng/ml)。比较三组患者血清铁蛋白的基线特征、左射分数、Killipfunctional分级及预后。结果:血清铁蛋白与左室射血分数(p=0.01)、Killipclass(p=0.03)、死亡率(p=0.03)有显著相关性。铁蛋白水平高低(1分位和3分位,≤120;[gt;220 ng/ml])与住院期间较高的心衰发生率和1年后死亡相关。结论:心肌梗死后血清铁蛋白升高与较差的短期和长期预后相关。
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引用次数: 0
Health Seeking Behaviour among Tribal Population of Shekharakund Colony, Wayanad, Kerala 喀拉拉邦瓦亚纳德Shekharakund殖民地部落人口的求医行为
Pub Date : 2023-01-01 DOI: 10.37506/ijphrd.v14i4.19757
Introduction: Health is the major pathway to human development. The individual self, various diseases, and theavailability and accessibility of health services all have an impact on how people seek health care.Objectives: The present study is aimed to assess the health seeking behaviours in the tribes of Paniya andKattunayakan in Shekharakund colony, Wayanad.Methods: Data to know the health seeking behaviour was collected using predesigned and pretested questionnairein the native language. Questions were asked about adequate health check-ups in nearby health centres, utilisationof health benefits from nearby PHCs, detection of pregnancy, antenatal check-ups, mode of delivery, immunizationof infants and prevalence of communicable and non-communicable disease (DM/HT) in the selected population,maternal and infant death in the community, knowledge about the antivenom for the snake envonemation, beliefin black magic in causation and treatment of disease.Results: Majority of the study population above 35yrs of age, did not seek health care benefits. 99% of the tribalpopulation found it difficult to take leave from work, 92% complained about long waiting time, 48 % were notsatisfied with the treatment, 95% of respondents said due to unavailability of doctors during the time they visited,98% agreed the distance of health centre was long for them to visit every time. 52.9% of tribal population preferredallopathic treatment over traditional healers. Only 29.4% of the population were aware of snake anti-venom.Conclusions: When treatment is sought, traditional medicines and healers play an important role in maintaininghealth and well-being among the ethnic groups. Traditional medicines and healers were preferred for treatment ofboth ‘simple and complicated diseases’ because of easy accessibility. They are aware of the superiority of modernhealth services but are hesitant to employ them due to the potential time loss.
健康是人类发展的主要途径。个人自我、各种疾病以及卫生服务的可得性和可及性都对人们寻求卫生保健的方式产生影响。目的:本研究旨在评估瓦亚纳德Shekharakund殖民地Paniya和kattunayakan部落的求医行为。方法:采用预先设计和预测的本族语问卷,收集青少年的求医行为资料。询问的问题包括:在附近的保健中心进行充分的健康检查、利用附近的初级保健中心提供的保健福利、怀孕检测、产前检查、分娩方式、婴儿免疫接种以及选定人群中传染性和非传染性疾病(DM/HT)的流行情况、社区中孕产妇和婴儿死亡情况、对蛇环境抗蛇毒血清的了解、相信疾病的因果关系和治疗中的黑魔法。结果:大多数35岁以上的研究人群没有寻求医疗保健福利。99%的部落人口发现很难请假,92%的人抱怨等待时间长,48%的人对治疗不满意,95%的受访者表示由于他们就诊时没有医生,98%的人认为每次就诊的医疗中心距离很远。52.9%的部落人口选择对抗疗法而不是传统疗法。只有29.4%的人知道蛇抗毒液。结论:在寻求治疗时,传统药物和治疗师在维持少数民族群体的健康和福祉方面发挥了重要作用。由于容易获得,传统药物和治疗师更倾向于治疗“简单和复杂的疾病”。他们意识到现代保健服务的优越性,但由于潜在的时间损失,他们对雇用这些服务犹豫不决。
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引用次数: 0
To Study the Clinical and Etiological Profile of Patients with Hepatic Encephalopathy 目的:探讨肝性脑病的临床及病因特点
Pub Date : 2023-01-01 DOI: 10.37506/ijphrd.v14i4.19790
Hepatic encephalopathy (HE) is a term used to describe a reversible syndrome of impaired brain function involvinga complex spectrum of nonspecific neurological and psychiatric manifestations occurring in patients of severeacute or chronic liver insufficiency. Hepatic encephalopathy (HE) is one of the most devastating complication ofcirrhosis having high morbidity and mortality. There is very limited data regarding the incidence and risk factorsof hepatic encephalopathy so this study is to find the clinical and etiological profile of hepatic encephalopathy.Methodology: The study was conducted in patients visited in OPD/IPD of medicine department, SGRDIMSR,Amritsar (Punjab) in the time period from 1 April 2021 to 31 July 2022. A total of 150 patients were taken up forthis study. All the diagnosed patients of liver cirrhosis of any etiology (Recently detected or old patients) wereincluded in the study.FindingsIn this study most of patients were males (81%) in the age group of 31 to 60 yrs (65%). Most common etiologyfound to be alcoholic (53%) with presenting symptoms of altered talks(51%).Conclusion: Education of the society about the precipitating factors can lead to early detection of hepaticencephalopathy and thus decrease the morbidity and mortality related to it. So there is need for Screeningprograms and education.
肝性脑病(HE)是一个术语,用于描述一种可逆的脑功能受损综合征,涉及复杂的非特异性神经和精神表现,发生在严重急性或慢性肝功能不全患者中。肝性脑病(HE)是肝硬化最具破坏性的并发症之一,具有很高的发病率和死亡率。关于肝性脑病的发病率和危险因素的资料非常有限,因此本研究旨在了解肝性脑病的临床和病因学概况。方法:研究对象为2021年4月1日至2022年7月31日在阿姆利则(旁遮普省)SGRDIMSR内科门诊/IPD就诊的患者。这项研究共纳入了150名患者。所有诊断为肝硬化的任何病因的患者(新近发现或老年患者)都被纳入研究。在本研究中,大多数患者为男性(81%),年龄在31 - 60岁(65%)。最常见的病因是酒精中毒(53%),伴有说话改变的症状(51%)。结论:社会对肝性脑病的发病因素进行教育,可以早期发现肝性脑病,从而降低肝性脑病的发病率和死亡率。所以我们需要筛查项目和教育。
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引用次数: 0
Urate Nephropathy: A Rare Case Report 尿酸肾病:罕见病例报告
Pub Date : 2023-01-01 DOI: 10.37506/ijphrd.v14i4.19809
Acute hyperuricemia most commonly occurs in patients who experience tumor-lysis syndrome. Hyperuricemiaalong with other electrolyte abnormalities like hyperkalemia, hypocalcemia, and hyperphosphatemia leads to acutekidney injury (AKI) due to acute uric acid nephropathy which is associated with significant morbidity. High riskpatients are thus closely monitored for signs of these laboratory abnormalities. Extreme exercise, rhabdomyolysis,and seizures are rare causes of acute hyperuricemia. Serum uric acid level is not routinely monitored as a partof postictal labs. We report an unusual case of AKI in a young male and no associated rhabdomyolysis who wasfound to have acute uric acid nephropathy. Timely administration of Rasburicase prevented the need for dialysisin this patient and led to complete renal recovery. This case illustrates the importance of doing a urine microscopyand checking uric acid level in patients who develop unexplainable AKI, as timely management helps improveoutcome.
急性高尿酸血症最常见于肿瘤溶解综合征患者。高尿酸血症与其他电解质异常,如高钾血症、低钙血症和高磷血症,可导致急性尿酸肾病引起的急性肾损伤(AKI),其发病率很高。因此,应密切监测高风险患者的这些实验室异常迹象。剧烈运动、横纹肌溶解和癫痫发作是引起急性高尿酸血症的罕见原因。血清尿酸水平不是常规监测的一部分,作为阳性实验室。我们报告一个不寻常的病例AKI在年轻男性和没有相关的横纹肌溶解谁被发现有急性尿酸肾病。及时给予Rasburicase防止了该患者透析的需要,并导致肾脏完全恢复。本病例说明了在发生不明原因AKI的患者中进行尿液显微镜检查和检查尿酸水平的重要性,因为及时处理有助于改善预后。
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引用次数: 0
Perceptions regarding Flipped Classroom teaching method among first year MBBS students in a Medical College in National Capital Region, India 印度国家首都地区某医学院MBBS一年级学生对翻转课堂教学方法的看法
Pub Date : 2023-01-01 DOI: 10.37506/ijphrd.v14i4.19747
Background: Flipped classroom aims at exposing the students to teaching material outside of class first andutilizing the class time in deeper understanding of the topic with the discussion in the presence of the teacher. It isa method of teaching learning wherein the students take responsibility of their learning. The present study was toconducted to introduce flipped classroom approach as teaching learning method and to obtain students feedback.Materials and method: The study was descriptive study done in the Department of Anatomy after obtaining theIEC clearance. First year MBBS students who volunteered to participate (138 out of 150) were included in the studyafter obtaining informed consent. The students were given a pre-class reading material in form of PowerPointPresentation with voice over for the topics selected for flipped class using Institutional Learning ManagementSystem (LMS) seven days before the class. Class time was utilized in discussion of the topic. A questionnairewas used which was validated by other faculty members. Responses were collected using a 5 point Likert scale.Analysis was done by Microsoft Excel 2010.Results: The concept of flipped classroom was well accepted by the students. It was observed that 70% of thestudents found flipped classroom is more interesting method of learning anatomy compared to traditional lectures.30% of the students believed flipped class required more time and more preparation. They were of the view thatthese classes were more interesting, interactive, and motivated them to learn compared to the didactic lectures.Conclusion: Flipped classroom is not a new concept. However, in our country this concept of teaching learning isnot very commonly used in medical colleges and can be used as an alternative to the traditional lectures for betterunderstanding of the topic and can be used more often.
背景:翻转课堂的目的是让学生首先接触到课堂外的教材,利用课堂时间在老师在场的情况下进行讨论,对主题有更深的理解。这是一种教学方法,学生对自己的学习负责。本研究旨在将翻转课堂作为一种教学方法,并获得学生的反馈。材料和方法:本研究为描述性研究,在获得iec许可后在解剖学系完成。自愿参与的MBBS一年级学生(150人中有138人)在获得知情同意后被纳入研究。课前七天,学生们通过机构学习管理系统(LMS)获得了一份ppt形式的课前阅读材料,并为翻转课堂选择的主题配上语音。课堂时间被用来讨论这个话题。我们使用了一份问卷,问卷得到了其他教员的认可。问卷采用5分李克特量表收集。使用Microsoft Excel 2010进行分析。结果:翻转课堂的概念被学生接受。据观察,70%的学生认为,与传统课堂相比,翻转课堂是一种更有趣的解剖学学习方式。30%的学生认为翻转课堂需要更多的时间和准备。他们认为,这些课程更有趣,互动,并激励他们学习相比说教的讲座。结论:翻转课堂并不是一个新概念。然而,在我国,这种教学概念在医学院校中并不常用,可以作为传统讲座的替代方案,更好地理解主题,并且可以更频繁地使用。
{"title":"Perceptions regarding Flipped Classroom teaching method among first year MBBS students in a Medical College in National Capital Region, India","authors":"","doi":"10.37506/ijphrd.v14i4.19747","DOIUrl":"https://doi.org/10.37506/ijphrd.v14i4.19747","url":null,"abstract":"Background: Flipped classroom aims at exposing the students to teaching material outside of class first andutilizing the class time in deeper understanding of the topic with the discussion in the presence of the teacher. It isa method of teaching learning wherein the students take responsibility of their learning. The present study was toconducted to introduce flipped classroom approach as teaching learning method and to obtain students feedback.Materials and method: The study was descriptive study done in the Department of Anatomy after obtaining theIEC clearance. First year MBBS students who volunteered to participate (138 out of 150) were included in the studyafter obtaining informed consent. The students were given a pre-class reading material in form of PowerPointPresentation with voice over for the topics selected for flipped class using Institutional Learning ManagementSystem (LMS) seven days before the class. Class time was utilized in discussion of the topic. A questionnairewas used which was validated by other faculty members. Responses were collected using a 5 point Likert scale.Analysis was done by Microsoft Excel 2010.Results: The concept of flipped classroom was well accepted by the students. It was observed that 70% of thestudents found flipped classroom is more interesting method of learning anatomy compared to traditional lectures.30% of the students believed flipped class required more time and more preparation. They were of the view thatthese classes were more interesting, interactive, and motivated them to learn compared to the didactic lectures.Conclusion: Flipped classroom is not a new concept. However, in our country this concept of teaching learning isnot very commonly used in medical colleges and can be used as an alternative to the traditional lectures for betterunderstanding of the topic and can be used more often.","PeriodicalId":13368,"journal":{"name":"Indian Journal of Public Health Research and Development","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135749314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of Anxiety and Associated Risk Factors among General Public During COVID-19 Pandemic: A Community Based Study COVID-19大流行期间公众焦虑及相关危险因素评估:一项基于社区的研究
Pub Date : 2023-01-01 DOI: 10.37506/ijphrd.v14i4.19753
Background: Lockdown represents a remarkably effective strategy of social distancing to break the chain oftransmission of COVID-19. This state of lockdown led to a significant influence on physical and mental wellbeingof people. The present study was conducted to assess the impact of COVID-19 pandemic on anxiety level ofgeneral public and find out the associated factors.Methods: The present web based cross-sectional study was carried out among 450 participants in India in themonth of May 2020. Data collection was done using online Google form. A semi-structured questionnaire wasused. Generalized Anxiety Disorder Scale-7 (GAD-7) Scale was used to assess anxiety symptoms among theparticipants. Descriptive Statistics and Chi-square test were done using SPSS version 21.Results: Age of the participants ranged between 18 to 71 years. Nearly one-third of the participants were health careprofessionals. Symptoms of mild anxiety was reported by 17.1% of participants, while 20.2% reported moderateanxiety. Anxiety was found to be significantly more among female gender, health care professional and among thestudy participants who were going to work daily.Conclusion: Covid-19 pandemic has increased the anxiety level among general public.
背景:封锁是打破COVID-19传播链的一种非常有效的社交距离策略。这种封锁状态对人们的身心健康产生了重大影响。本研究旨在评估新冠肺炎大流行对公众焦虑水平的影响,并找出相关因素。方法:目前基于网络的横断面研究于2020年5月在印度的450名参与者中进行。数据收集使用在线Google表单完成。采用半结构化问卷。广泛性焦虑障碍量表-7 (GAD-7)用于评估参与者的焦虑症状。描述性统计和卡方检验采用SPSS 21版。结果:参与者年龄在18 - 71岁之间。近三分之一的参与者是卫生保健专业人员。17.1%的参与者报告了轻度焦虑的症状,而20.2%的参与者报告了中度焦虑。研究发现,女性、医疗保健专业人员和每天上班的研究参与者的焦虑程度明显更高。结论:新冠肺炎疫情增加了公众的焦虑水平。
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引用次数: 0
Assessment of Exposure to Factors Favoring Covid 19 Transmission among Medical Students in South Kerala during the First Wave of the Pandemic 在第一波大流行期间,南喀拉拉邦医学生暴露于有利于Covid - 19传播因素的评估
Pub Date : 2023-01-01 DOI: 10.37506/ijphrd.v14i4.19810
Transmission of SARS -Cov occurs primarily primarily between people through direct, indirect, or close contactwith infected people through infected secretions such as saliva and respiratory secretions. To prevent transmissionthere are several measures implanted by health authorities all over the world like social distancing, use of facemasks, hand washing or use of sanitizer, contact tracing and quarantine, isolation, etc. This study was intendedto determine medical students’ exposure (while at home due to lockdown) to environmental factors favoring thetransmission of Covid 19. After getting institutional ethical clearance a cross-sectional study was done among82 medical students. The mode of data collection was through google forms. The students were asked to report thefactors (already practicing) that favor covid 19 transmission to which they were exposed during the last 2 weeks.All the study subjects were tested for Covid 19 during the next 2-week period. Data were analyzed descriptivelyto find out the number and percentage. The median age of the sample was 22 years ( Q1 21, Q3 23). Comorbiditiesthat could favor covid 19 transmission were present in 12.2% of students. The percentage of students who visitedcrowded places in the last 2 weeks which could increase the risk of transmission ranged from 6 % to 29%. Socialdistancing was practiced by 51%, Wearing a mask was practiced by 62%, and using soap/sanitizer by 73% ofmedical students. Out of the total 82 medical students 4 tested positive for Covid 19. The study concluded thatexposure to risk factors of covid 19 transmission was optimum among medical students during the pandemicphase.
SARS冠状病毒的传播主要发生在人与人之间,通过唾液和呼吸道分泌物等受感染的分泌物与感染者直接、间接或密切接触。为防止传播,世界各地的卫生当局采取了一些措施,如保持社交距离、使用口罩、洗手或使用消毒剂、接触者追踪和隔离、隔离等。本研究旨在确定医学生暴露于有利于Covid - 19传播的环境因素(由于封锁而在家中)的情况。在获得机构伦理许可后,对82名医学生进行了横断面研究。数据收集的方式是通过google表单。学生们被要求报告他们在过去两周内接触到的有利于covid - 19传播的因素(已经在实施)。在接下来的两周内,所有研究对象都接受了Covid - 19检测。对数据进行描述性分析,找出数量和百分比。样本的中位年龄为22岁(Q1 21岁,Q3 23岁)。12.2%的学生存在可能有利于covid - 19传播的合并症。在过去两周内去过可能增加传播风险的拥挤场所的学生比例为6%至29%。51%的医学生保持社交距离,62%的医学生戴口罩,73%的医学生使用肥皂/消毒剂。在82名医学生中,有4人的新冠病毒检测呈阳性。该研究得出结论,在大流行阶段,医学生接触covid - 19传播风险因素的程度最高。
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引用次数: 0
Bacteriological Analysis of Bronchoalveolar Lavage Fluid in Patients with Respiratory Tract Infections 呼吸道感染患者支气管肺泡灌洗液的细菌学分析
Pub Date : 2023-01-01 DOI: 10.37506/ijphrd.v14i4.19796
Background and Aim: Bacterial respiratory infections are most commonly causes of illness for all age group patientsin ICU. Most of the patients suffer from urosepsis, postoperative disease and lower respiratory infection whenadmitted in ICU’s. Broncho alveolar lavage (BAL) is an ideal sample that allows the recovery of pathogens cellularand noncellular components from the epithelial surface of lower respiratory tract. This study was performed todetect pathogenic organisms by microscopy of BAL fluid and isolate and identify various bacteria and fungi fromBAL fluid in culture and analyze their antibiogram.Material and Methods: The cross-sectional prospective study was conducted in the Department of Microbiology,tertiary care teaching hospital, India. The study included 200 BAL samples taken from all consecutive patientsreferred with suspicion of pneumonia. Bronchial wash was done with the help of fibreoptic bronchoscope underlocal anaesthesia. All BAL samples were cultured on three bacteriological media agar plates using a sterile 4mmnichrome loop (0.01ml), and incubated at 37 C for 72 hours for quantitative bacterial culture using standardlaboratory techniques. Bacterial isolates were identified by performing standard microbiological procedures suchas study of colony morphology, Gram staining and standard biochemical tests.Results: Out of the total 200 samples, 120 (60%) were from males, and 80 (40%) were female patients. Thepredominant GNB was Klebsiella pneumoniae 45 (61%), followed by Pseudomonas aeruginosa 22(30%), Esch.coli 6(8%) and the fungal isolate was Aspergillus niger 5(1%). Klebsiella & Pseudomonas were highly sensitive toamikacin, piperacillin-tazobactam, imipenem, gentamycin, followed by tobramycin.Conclusion: Results of the present study demonstrate the high incidence of gram-negative isolates. The study alsosuggests that regular antimicrobial sensitivity monitoring should be done as most isolates are highly resistant tocephalosporin and other commonly used antimicrobials
背景与目的:细菌性呼吸道感染是ICU所有年龄组患者最常见的病因。ICU住院患者多出现尿脓毒症、术后疾病和下呼吸道感染。支气管肺泡灌洗(BAL)是一种理想的样品,可以从下呼吸道上皮表面恢复病原体的细胞和非细胞成分。本研究对BAL液进行病原微生物的显微镜检测,并从BAL液中分离鉴定培养的各种细菌和真菌,分析其抗生素谱。材料与方法:横断面前瞻性研究在印度三级护理教学医院微生物科进行。该研究包括从所有疑似肺炎的连续患者中采集的200份BAL样本。局部麻醉下在纤维支气管镜下进行支气管冲洗。所有BAL样品采用无菌4mmnicrome环(0.01ml)在三种细菌培养基琼脂板上培养,并使用标准实验室技术在37℃下孵育72小时进行定量细菌培养。通过菌落形态研究、革兰氏染色和标准生化试验等标准微生物学程序鉴定分离的细菌。结果:200例样本中,男性120例(60%),女性80例(40%)。GNB以肺炎克雷伯菌45(61%)、铜绿假单胞菌22(30%)、Esch;大肠杆菌6(8%)和分离真菌为黑曲霉5(1%)。克雷伯氏菌,假单胞菌对阿米卡星、哌哌西林-他唑巴坦、亚胺培南、庆大霉素高度敏感,其次为妥布霉素。结论:本研究结果表明革兰氏阴性分离株发病率高。该研究还建议应定期进行抗菌素敏感性监测,因为大多数分离株对头孢菌素和其他常用抗菌素具有高度耐药性
{"title":"Bacteriological Analysis of Bronchoalveolar Lavage Fluid in Patients with Respiratory Tract Infections","authors":"","doi":"10.37506/ijphrd.v14i4.19796","DOIUrl":"https://doi.org/10.37506/ijphrd.v14i4.19796","url":null,"abstract":"Background and Aim: Bacterial respiratory infections are most commonly causes of illness for all age group patientsin ICU. Most of the patients suffer from urosepsis, postoperative disease and lower respiratory infection whenadmitted in ICU’s. Broncho alveolar lavage (BAL) is an ideal sample that allows the recovery of pathogens cellularand noncellular components from the epithelial surface of lower respiratory tract. This study was performed todetect pathogenic organisms by microscopy of BAL fluid and isolate and identify various bacteria and fungi fromBAL fluid in culture and analyze their antibiogram.Material and Methods: The cross-sectional prospective study was conducted in the Department of Microbiology,tertiary care teaching hospital, India. The study included 200 BAL samples taken from all consecutive patientsreferred with suspicion of pneumonia. Bronchial wash was done with the help of fibreoptic bronchoscope underlocal anaesthesia. All BAL samples were cultured on three bacteriological media agar plates using a sterile 4mmnichrome loop (0.01ml), and incubated at 37 C for 72 hours for quantitative bacterial culture using standardlaboratory techniques. Bacterial isolates were identified by performing standard microbiological procedures suchas study of colony morphology, Gram staining and standard biochemical tests.Results: Out of the total 200 samples, 120 (60%) were from males, and 80 (40%) were female patients. Thepredominant GNB was Klebsiella pneumoniae 45 (61%), followed by Pseudomonas aeruginosa 22(30%), Esch.coli 6(8%) and the fungal isolate was Aspergillus niger 5(1%). Klebsiella &amp; Pseudomonas were highly sensitive toamikacin, piperacillin-tazobactam, imipenem, gentamycin, followed by tobramycin.Conclusion: Results of the present study demonstrate the high incidence of gram-negative isolates. The study alsosuggests that regular antimicrobial sensitivity monitoring should be done as most isolates are highly resistant tocephalosporin and other commonly used antimicrobials","PeriodicalId":13368,"journal":{"name":"Indian Journal of Public Health Research and Development","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135750841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Indian Journal of Public Health Research and Development
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