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Baseline Penile Ultrasound and Color Doppler Parameters – A Comparison Between Psychogenic and Vasculogenic Erectile Dysfunction Patients 基线阴茎超声和彩色多普勒参数-心理和血管源性勃起功能障碍患者的比较
Pub Date : 2021-07-16 DOI: 10.18311/IJMDS/2021/27292
N. Kaur, Janu Arora, R. Kaur, Nitin Gupta, V. Bhalla, Navdeep Kaur, Bhavneet Singh
Background and Objectives: There are many causes of erectile dysfunction (ED) like congenital anomalies, neurological, endocrinal, pharmacological, psychological, pathological or hemodynamic. Penile doppler ultrasound provides real-time evaluation of cavernosal vascular flow dynamics. Purpose of our study was to evaluate and compare the baseline penile ultrasound and color doppler vascular parameters in patients of ED to see if there was any significant difference between patients of psychogenic and vasculogenic ED (diagnosed on post Papaverine injection color doppler) without the use of intracavernosal Papaverine injection. To best of our knowledge such detailed comparison of baseline penile ultrasound and doppler parameters have not been published in literature. Methods: We have prospectively studied 32 patients of ED who underwent ultrasound, and color doppler pre-and post-papaverine intracavernosal injection. Baseline pre papaverine diameters of right and left cavernosal arteries were measured on grey scale ultrasound. Peak systolic velocity (PSV), end diastolic velocity (EDV) and resistive index (RI) of right and left cavernosal arteries were measured on color doppler before and after injecting intracavernosal papaverine injection. Patients were divided into normal study group (psychogenic ED), arterial insufficiency and venous leakage groups (vasculogenic ED) on the basis of post papaverine color doppler findings. Results: Eighteen patients showed normal study, 11 showed arterial insufficiency and 3 patients had venous leakage on post Papaverine injection color doppler. When base line prepapaverine vascular diameters and color doppler parameters were compared statistically, no significant difference was detected between and within these study groups. We have also compared Ed duration and IIEF scores among various study groups and found statistically significant difference between and within the groups. Conclusion: Use of a vasoactive agent like Papaverine with color Doppler is must to diagnose the vasculogenic ED.
背景与目的:导致勃起功能障碍(ED)的原因有很多,如先天性异常、神经系统、内分泌、药理、心理、病理或血流动力学等。阴茎多普勒超声提供海绵体血管流动动力学的实时评估。我们的研究目的是评估和比较ED患者的基线阴茎超声和彩色多普勒血管参数,看看心因性ED和血管源性ED(注射罂粟碱后彩色多普勒诊断)在不使用海绵内注射罂粟碱的情况下是否有显著差异。据我们所知,这样详细的比较基线阴茎超声和多普勒参数尚未发表在文献。方法:我们对32例经超声和彩色多普勒检查的ED患者进行了海绵体内注射罂粟碱前后的前瞻性研究。灰阶超声测量左、右海绵体动脉的基线前罂粟碱直径。用彩色多普勒测量海绵体内注射罂粟碱前后左右海绵体动脉的峰值收缩速度(PSV)、舒张末速度(EDV)和阻力指数(RI)。根据彩色多普勒超声检查结果将患者分为正常研究组(心因性ED)、动脉功能不全组和静脉漏组(血管源性ED)。结果:罂粟碱注射后彩色多普勒显示18例正常,11例动脉功能不全,3例静脉漏。当基线肾上腺血管直径和彩色多普勒参数进行统计学比较时,各组之间和组内没有发现显著差异。我们还比较了不同研究组的Ed持续时间和IIEF分数,发现组间和组内存在统计学上的显著差异。结论:应用血管活性药物如罂粟碱加彩色多普勒诊断血管源性ED是必要的。
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引用次数: 1
Students View on Medical Curriculum 学生对医学课程的看法
Pub Date : 2021-07-16 DOI: 10.18311/IJMDS/2021/27880
Tannabi Deka, S. Chakraborty, A. Bhatia, C. B. Manu
The Indian medical education system which is believed to be one of the largest in the world consists of 479 medical colleges which produces 60,845 doctors per year. Student’s evaluation of any teaching curriculum is a firmly recommended part of the teaching-learning process and is aimed at achieving the desired objectives of producing competent doctors. This cross-sectional study was conducted using a pre-designed questionnaire on 100 medical students studying at undergraduate level in NEIGRIHMS. Primary objective: To study the views of the students regarding the existing medical curriculum. Secondary objective: Whether the present mode of teaching covers all the aspects of teaching or not. Our study found that 74% of third-year and 74% of final year MBBS students were satisfied with the current MBBS curriculum. Significant number of students also felt that ward rounds should commence from first year MBBS with students interested to participate in other activities during the MBBS curriculum. These inputs can be considered for making amendments in the MBBS curriculum to create a student-centric environment.
印度医学教育体系被认为是世界上最大的医学教育体系之一,由479所医学院组成,每年培养60,845名医生。学生对任何教学课程的评价都是教学过程中被强烈推荐的一部分,旨在实现培养合格医生的预期目标。本横断面研究采用预先设计的调查问卷对100名在NEIGRIHMS就读本科阶段的医学生进行调查。主要目的:了解学生对现有医学课程的看法。次要目标:目前的教学模式是否涵盖了教学的所有方面。我们的研究发现,74%的三年级和74%的最后一年MBBS学生对目前的MBBS课程感到满意。相当多的学生也认为查房应该从MBBS的第一年开始,学生们有兴趣参加MBBS课程中的其他活动。可以考虑这些输入来修改MBBS课程,以创建一个以学生为中心的环境。
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引用次数: 0
Incidence of Plate Removal and its Correlation to the Site of Injury in Patients with Maxillofacial Trauma: A Retrospective Study 颌面外伤患者钢板取出发生率及其与损伤部位的相关性:一项回顾性研究
Pub Date : 2021-07-16 DOI: 10.18311/IJMDS/2021/26745
G. Venkatesa, N. Sahoo
Background: Maxillofacial injuries can be classified according to its anatomical location of the involved bone and by the degree of involvement like simple, compound or comminuted. Regardless of the site of involvement and nature of trauma the fracture can be addressed by closed and open methods of reduction. Objective: The aim of this retrospective study was to record the incidence and factors associated with plate removal in patients with maxillofacial trauma. Materials and Methods: Records of 280 cases managed for maxillofacial trauma in the last (5 years) period from January 2010 to Dec 2014 by open reduction and internal fixation (ORIF) with osteosynthesis plates were analyzed at a tertiary health care facility. Logistic regression analysis was done to find an association between the variables studied and incidence of plate removal. Results: 32 cases (11.42%), 55 number of implants underwent removal of plates due to reasons ranging from infection(50%), Plate exposure(9.375%), treatment failure(15.625%), palpability(12.50%), and persistent pain(12.50%), Zygomatic buttress and Parasymphysis sites had highest incidence of plate removal compared to other sites. Being a female [OR 9.87(4.21–10.72)], age groups of 46-60 [OR 6.39(4.43-9.62)], 31-45 [OR 11.25(6.81-13.77)] and 15-30 [OR 10.01(5.74-12.22)], infra orbital rim among sites [OR 2.03 (1.48-4.67)] significantly increased the odds of incidence of plate removal. Conclusion: In our retrospective analysis, the overall incidence of plate removal was 11.42%. Maximum plate removals were from Zygomatico-Maxillary Buttress and Symphysis and Parasymphysis regions. Infection was found to be the most common cause of plate removal.
背景:颌面部损伤可根据受累骨的解剖位置和受累程度进行分类,如单纯性、复合性和粉碎性。无论受累部位和创伤的性质如何,骨折都可以通过封闭和开放复位方法来解决。目的:本回顾性研究的目的是记录颌面部外伤患者钢板取出的发生率和相关因素。材料与方法:对某三级医疗机构2010年1月至2014年12月间采用骨固定钢板切开复位内固定(ORIF)治疗颌面部外伤的280例病例进行分析。进行了Logistic回归分析,以发现所研究的变量与钢板去除发生率之间的关联。结果:32例(11.42%),55例植入物因感染(50%)、钢板暴露(9.375%)、治疗失败(15.625%)、可触性(12.50%)和持续疼痛(12.50%)等原因取出钢板,其中颧支撑和副骨部位的钢板取出率最高。女性[OR 9.87(4.21-10.72)]、46-60岁[OR 6.39(4.43-9.62)]、31-45岁[OR 11.25(6.81-13.77)]和15-30岁[OR 10.01(5.74-12.22)]年龄组,眶下缘部位[OR 2.03(1.48-4.67)]显著增加钢板取出的发生率。结论:在我们的回顾性分析中,钢板取出的总发生率为11.42%。最大的钢板移除是在颧-上颌支撑区、联合区和副联合区。感染是拔牙最常见的原因。
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引用次数: 0
Evaluation of the Component Separation Technique for Treatment of Patients with Large Incisional Hernia 成分分离技术治疗大切口疝的疗效评价
Pub Date : 2021-07-16 DOI: 10.18311/IJMDS/2021/26738
Kunwar Aggarwal
Background: Incisional hernia remains a frequent complication of abdominal surgery. Results of surgical repair are disappointing with recurrence rates of suture repair being in the range of 5–63% depending upon the type of repair used, with better results using mesh implantation. In extreme cases a large hernial defect exists with a “loss of abdominal domain”. In addition, the approximated rectus muscles under tension become hypoper fused leading to atrophy and increased chances of recurrence. For the management of such large hernias, interest has been generated in the “ Component Separation Technique ”. This technique relaxes abdominal wall by translation of muscular layers without severing the innervation and blood supply, with or without the mesh augmentation. This can accommodate for defects up to 25–30cm in the waistline. However, wound complications are frequent and reported in up to half of the patients. Thus, the study was planned in view of the potential benefits of “CST” and its capability to restore lost abdominal domain. Methods: The study was conducted on 20 patients with “Large Incisional Hernia” with defect size >5cm or with a surface area >50cm 2 operated upon with component separation. Outcome was measured over a follow up period of three months in terms of recurrence and other local complications. Result: There were 20 patients [3 men and 17 women; 70% cases above the age of 50years]. Mean defect size was 9.5cm [range = 6–20cm]. Average body mass index was 28.97kg/m 2 [range = 22–37kg/ m 2 ]. Mean duration of hospital stay was 9 days [range = 5–21 days]. Early complications occurred in 15% (3/20) cases and post-operative abdominal compartment or recurrence was not reported over a follow up period of 3 months. Conclusions: It is finally concluded that “Large Incisional Hernias” can be effectively treated by “Component Separation Technique”
背景:切口疝仍然是腹部手术的常见并发症。手术修复的结果令人失望,根据使用的修复类型,缝线修复的复发率在5-63%之间,使用补片植入效果更好。在极端情况下,存在巨大的疝缺损,并伴有“腹部区域的丧失”。此外,紧绷的近直肌融合不良,导致萎缩和复发的机会增加。对于这种大疝的治疗,“成分分离技术”引起了人们的兴趣。该技术通过肌肉层的平移来放松腹壁,而不切断神经支配和血液供应,有或没有网状物增强。这可以适应腰围25 - 30厘米的缺陷。然而,伤口并发症是常见的,报告在多达一半的患者。因此,考虑到“CST”的潜在益处及其恢复失去的腹部区域的能力,计划进行这项研究。方法:选取缺损尺寸>5cm或表面积>50cm 2的“大切口疝”患者20例,采用组份分离手术。结果是在随访三个月后根据复发率和其他局部并发症来衡量的。结果:共20例患者,男3例,女17例;50岁以上病例占70%]。平均缺陷尺寸为9.5cm[范围= 6-20cm]。平均体重指数28.97kg/ m2[取值范围为22 ~ 37kg/ m2]。平均住院时间9天[范围5 ~ 21天]。15%(3/20)病例出现早期并发症,术后腹腔隔室或随访3个月未见复发。结论:“成分分离技术”可有效治疗“大切口疝”。
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引用次数: 0
A Study to Evaluate the Effectiveness of Inhaled Corticosteroid/Long-Acting Beta Agonist Combination and Assessment of Health-Related Quality of Life Among COPD Patients on this Therapy 一项评估吸入皮质类固醇/长效β激动剂联合治疗COPD患者健康相关生活质量的研究
Pub Date : 2021-07-16 DOI: 10.18311/IJMDS/2021/26829
A. Kaur, V. Sehgal, Jasbir Singh, S. Singh, Meenakshi Raju
Background: Do combined inhalers offer additional benefits or harms in people with chronic obstructive pulmonary disease compared with the bronchodilator alone? The present study was conducted to evaluate the effectiveness of inhaled corticosteroid/long acting beta agonist combination and to assess the health related quality of life among COPD patients.  Methods: A prospective, comparative study was conducted in department of Pulmonary Medicine, Government Medical College and Rajindra Hospital, Patiala. A total of 80 patients were enrolled, and randomly allocated in two groups with 40 patients in each group. In group 1- Budesonide/formoterol (200/6 µg or 400/6 µg), and in group 2- Fluticasone/salmeterol (250/50 µg) was prescribed. The effectiveness was evaluated by assessing exacerbation rate, and breathlessness Modified Medical Research Council (mMRC) grade. Health related quality of life was assessed using St. George’s Respiratory Questionnaire (SGRQ). All the observations thus made were statistically analyzed using chi-square test and t-test.  Results: In present study, male patients (n=63) were more than female patients (n=17). In group 1 significant improvement was observed in breathlessness mMRC grade between visit 0 and 2 nd (x2 = 8.50, p=0.004), and between visit 1 st and 2 nd (x2 = 7.24, p=0.007). Similarly, among group 2, significant improvement was seen in mMRC grade between visit 0 and 2 nd (x2 = 8.39, p=0.004), and between visit 1 st and 2 nd  (x2 = 5.05, p=0.025). But, no significant difference was seen between group 1 and 2 mMRC grade (p > 0.05). There was no statistically significant difference between group 1 and group 2 exacerbation episodess (x2 = 2.13,p>0.05). In SGRQ mean total score, no significant difference was present between group 1 and 2 (p>0.05).  Conclusions: Budesonide Formoterol (BFC) and Fluticasone Salmeterol (FSC) belongs to same group of drug class i.e. inhaled corticosteroid with long acting beta agonist combination and are used to treat exacerbations in moderate to severe COPD patients. BFC and FSC are equally effective in present study.
背景:与单独使用支气管扩张剂相比,联合吸入器对慢性阻塞性肺疾病患者是否有额外的益处或危害?本研究旨在评估吸入皮质类固醇/长效β激动剂联合治疗的有效性,并评估COPD患者的健康相关生活质量。方法:对帕提亚拉市政府医学院肺内科与拉金德拉医院进行前瞻性比较研究。共纳入80例患者,随机分为两组,每组40例。1组布地奈德/福莫特罗(200/6µg或400/6µg), 2组氟替卡松/沙美特罗(250/50µg)。通过评估加重率和呼吸困难程度(mMRC)评分来评估疗效。采用圣乔治呼吸问卷(SGRQ)评估健康相关生活质量。所有观察结果采用卡方检验和t检验进行统计学分析。结果:本组患者中,男性63例,女性17例。第1组患者呼吸困难mMRC评分在第0 ~ 2次就诊期间(x2 = 8.50, p=0.004)和第1 ~ 2次就诊期间(x2 = 7.24, p=0.007)均有显著改善。同样,在第2组中,mMRC分级在第0至第2次就诊期间(x2 = 8.39, p=0.004)和第1至第2次就诊期间(x2 = 5.05, p=0.025)均有显著改善。mMRC分级1组与2组间差异无统计学意义(p > 0.05)。1组与2组急性加重发作次数比较,差异无统计学意义(x2 = 2.13,p>0.05)。SGRQ平均总分1组与2组比较差异无统计学意义(p>0.05)。结论:布地奈德福莫特罗(BFC)与氟替卡松沙美特罗(FSC)同属吸入性皮质类固醇与长效受体激动剂联用一类药物,可用于治疗中重度COPD患者的加重期。BFC和FSC在本研究中同样有效。
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引用次数: 0
Online Teaching versus Traditional Teaching – A Survey among Medical Students in Covid 19 Pandemic 在线教学与传统教学——对新冠肺炎大流行医学院学生的调查
Pub Date : 2021-07-16 DOI: 10.18311/IJMDS/2021/27691
Anuradha Dehiya, Ravikant Sharma, M. Khullar, Vanita Gupta, Rimpi Gupta
For decades, scholars have debated which mode of education is superior amongst online versus traditional teaching. Some argue in favour of traditional or face to face teaching and others consider online teaching better. Still others suggested hybrid or blended mode of teaching as the most effective and productive method. This shift in strategy for medical education delivery has been driven by external forces beyond the influence of the institutions as well as by their internal dynamic. However, students’ perception towards online teaching as compared to traditional teaching has largely been overlooked. Aims and Objectives: This study or survey in covid pandemic intends to fill this void in the literature, and explore medical students’ perception and obtain their feedback towards online learning or teaching versus traditional teaching (face to face) mode of education in the medical field. Material and Method: Present survey included 1100 medical students from different medical colleges situated under different universities in North India. Survey was developed, which included a total of 14 questions (5 were demographical). After obtaining their responses, statistical analysis of responses was done. Conclusion: The results of present study concluded that medical students preferred traditional teaching over online mode of teaching.
几十年来,学者们一直在争论在线教育和传统教育哪种模式更好。一些人赞成传统的或面对面的教学,而另一些人认为在线教学更好。还有一些人认为混合或混合教学模式是最有效和最有成效的方法。医学教育战略的这种转变是由机构影响之外的外部力量以及它们的内部动态推动的。然而,与传统教学相比,学生对在线教学的看法在很大程度上被忽视了。目的和目的:本研究或调查旨在填补这一文献空白,探讨医学生对医学领域在线学习或教学与传统教学(面对面)教育模式的看法和反馈。材料与方法:本调查包括1100名来自印度北部不同大学下属不同医学院的医学生。该调查共包括14个问题(其中5个是人口学问题)。得到他们的回复后,对回复进行统计分析。结论:医学生对传统教学模式的偏好高于网络教学模式。
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引用次数: 0
Simultaneous Gap Arthroplasty and Distraction Osteogenesis in the Management of Unilateral Bony TMJ Reankylosis – A Case Report 同时间隙关节置换术和牵张成骨治疗单侧骨性颞下颌关节再强直1例报告
Pub Date : 2021-01-29 DOI: 10.18311/IJMDS/2021/25916
Vasantha Kumar Vanmathi, Varalakshmi R Parasuraman, R. Vanmathi
Temporomandibular Joint ankylosis is the adhesion of the condyle of the mandible to the base of the skull. It is the most common cause of hypoplasia of the mandible and eventual facial asymmetry. This case report describes the management of unilateral bony re-ankylosis of temporomandibular joint after the failure of a costochondral graft in an eight-year-old girl. The management of temporomandibular ankylosis presents a major challenge due to its increased reoccurrence rate. In the present case, simultaneous gap arthroplasty and distraction osteogenesis were performed to separate the ankylotic mass and lengthen the ramus-condyle unit. The one year follow-up of the patient showed adequate mouth opening. We recommend concomitant gap arthroplasty and distraction osteogenesis for effectively managing temporomandibular joint bony ankylosis.
颞下颌关节强直是下颌骨髁突与颅骨底部的粘连。这是下颌发育不全和最终面部不对称的最常见原因。本病例报告描述了一名八岁女孩在肋软骨移植失败后颞下颌关节单侧骨再强直的治疗。颞下颌强直的管理提出了一个主要的挑战,由于其复发率增加。在本病例中,同时进行间隙关节置换术和牵张成骨术以分离强直性肿块并延长支髁单位。随访1年,患者口腔张开程度正常。我们建议同时进行间隙关节置换术和牵张成骨术,以有效地治疗颞下颌关节骨性强直。
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引用次数: 0
Self-perceived competence of contemporary restorative practices of dental students in North India: A pilot study 印度北部牙科学生当代恢复性实践的自我感知能力:一项试点研究
Pub Date : 2021-01-29 DOI: 10.18311/IJMDS/2021/26669
Rudra Kaul, S. Kaur, Ashish Choudhary, V. Kaul, Rahat Saleem, Iggdc Jammu Jammu Jammu Kashmir – India Endodontics
Background: There has been a paradigm shift in the restorative dentistry practiced in the clinics with an increased share of resin-composites in contrast to dental amalgam due to various factors, however, this has not found its way into the Indian dental school curriculum. Aim: To evaluate the self-perceived competence of contemporary restorative practices of dental students in North India. Materials and Methods: 232 dental students from 4 colleges in North India completed a survey comprising 11 polar questions about their perception of contemporary restorative dental practice and their curriculum update regarding the same. Further, the collected data was tabulated and finally extracted data was subjected to descriptive analysis using Chi-square test. Results: All 11 questions showed statistically significant responses. Only 15.5% of students thought that the current curriculum of restorative dentistry was adequate. Moreover, only 20.7% of the respondents were confident about using rubber dam for isolation. About 93.1% felt that the quality of their composite restorations was not at par with those seen on social media. A clear majority of 91.4% felt that the maximum uploads of restorative dentistry involved composite restorations. A huge number of 91.45% did not use rubber dam for isolation in composite restorations. 79.3% students felt that the current curriculum is not teaching them about the various instruments, and developing their skills about instrumentation and operative procedures of composite restorations matching the trending composite practices. Conclusion: Considering the results of this study as the student’s mandate will help shape the guidelines for possibly a new curriculum of conservative dentistry in India.
背景:由于各种因素,与牙科汞合金相比,树脂复合材料的比例增加,在诊所中进行的修复牙科实践中已经发生了范式转变,然而,这还没有进入印度牙科学校的课程。目的:评价北印度牙科学生当代修复实践的自我认知能力。材料和方法:来自印度北部4所大学的232名牙科学生完成了一项调查,其中包括11个关于他们对当代修复牙科实践的看法以及他们对此的课程更新的极端问题。将收集到的数据制成表格,最后提取的数据采用卡方检验进行描述性分析。结果:11个问题的回答均有统计学意义。只有15.5%的学生认为目前的牙科修复课程是足够的。此外,只有20.7%的受访者对使用橡胶坝进行隔离有信心。大约93.1%的人认为他们的复合修复体的质量与社交媒体上看到的质量不一样。绝大多数(91.4%)的人认为修复牙科的最大上传涉及复合修复。在复合修复中,有91.45%的人没有使用橡胶坝进行隔离。79.3%的学生认为目前的课程没有教授他们各种仪器的知识,也没有培养他们对复合修复的仪器和操作程序的技能,与趋势的复合实践相匹配。结论:考虑到这项研究的结果作为学生的任务,将有助于塑造可能在印度保守牙科新课程的指导方针。
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引用次数: 0
Prevalence and Antibiotic Resistance Pattern of Staphylococcus aureus isolates from Clinical samples at a Tertiary Care Hospital, North India 北印度一家三级保健医院临床样本中金黄色葡萄球菌分离株的流行率和抗生素耐药模式
Pub Date : 2021-01-29 DOI: 10.18311/IJMDS/2021/25742
S. Tyagi, A. Oberoi
Background: Staphylococcus aureus (S. aureus) is a well recognized nosocomial and community acquired pathogen which is implicated in causing a wide spectrum of superficial, deep pyogenic infections and toxin mediated illnesses. Localized infections sometimes progress to systemic infections, while ‘spontaneous’ bacteraemia also occur without an evident septic focus, particularly in chronic debilitated immunocompromised patients. Emergence of drug resistance to penicillins and penicillinase-resistant penicillins (i.e., oxacillin and methicillin) is a globally recognized problem. Methicillin Resistant Staphylococcus aureus isolates are also important with respect to the range of nosocomial infections it causes, leading to an increase in the hospital expenditure and mortality or morbidity rate. The increased prevalence of such resistant strains has narrowed down the list of available therapeutic options. Therefore, information regarding the prevalence of S. aureus infections in a health care setting and determining its current antibiotic resistance profile becomes crucial in selecting appropriate treatment regime. Therefore, the current study was done in the department of Microbiology to determine the prevalence of S. aureus infections and the antibiotic resistance pattern of S. aureus isolates from various clinical specimens at our tertiary care hospital in North India. Materials and Methods: A one year prospective study was carried out in the Department of Microbiology, at a tertiary care hospital in North India where non-duplicate strains of S. aureus isolated from various clinical specimens received in the Microbiology laboratory were studied. All S. aureus isolates were subjected to Antibiotic Susceptibility Testing using Kirby Bauer’s disk diffusion method on Mueller Hinton Agar plates in accordance to CLSI guidelines. The antibiotics tested included Penicillin (10U), Amoxicillin-clavulanic acid (20/10μg), Sulphamethoxazole-trimethoprim (1.25/23.75μg), Ciprofloxacin (5μg), Erythromycin (15μg), Clindamycin (2μg), Vancomycin (30μg), Teicoplanin (30μg) and Linezolid (30μg). Results: A total of 23,699 clinical specimens were processed in the laboratory while conducting this study, from which 1233 clinical isolates of S. aureus were identified and processed further. Among all clinical specimens, pyogenic samples (63.1%) yielded maximum number of S. aureus strains followed by blood samples (29.9%) and urine samples (4.8%). S. aureus infection was more evident in hospitalized 71.2% patients than in OPD patients 28.8%. Seasonal variation was also seen in isolation of S. aureus , with a higher percentage of isolates obtained during summer season than during winter season. On antibiotic susceptibility testing, 49.6% strains were Methicillin Resistant. Majority of the isolates were found resistant to Penicillin (92.1%), followed by Erythromycin (59%). Almost half of the total isolates were resistant to Sulphamethoxazole-Trimethoprim (49.3%) followed by Am
背景:金黄色葡萄球菌(金黄色葡萄球菌)是一种公认的医院和社区获得性病原体,它涉及引起广泛的浅表、深部化脓性感染和毒素介导的疾病。局部感染有时会发展为全身性感染,而“自发性”菌血症也会发生,但没有明显的败血症灶,特别是在慢性衰弱免疫功能低下的患者中。出现对青霉素类和耐青霉素酶青霉素类(即恶西林和甲氧西林)的耐药性是一个全球公认的问题。耐甲氧西林金黄色葡萄球菌分离株在其引起的院内感染范围方面也很重要,导致医院支出和死亡率或发病率增加。这种耐药菌株的日益流行缩小了可用治疗方案的范围。因此,医疗机构中有关金黄色葡萄球菌感染流行情况的信息,以及确定其当前抗生素耐药概况,对于选择适当的治疗方案至关重要。因此,本研究在印度北部三级医院的微生物科进行,以确定金黄色葡萄球菌感染的流行情况和从各种临床标本中分离出的金黄色葡萄球菌的抗生素耐药模式。材料和方法:一项为期一年的前瞻性研究在印度北部一家三级医院的微生物科进行,研究了从微生物实验室收到的各种临床标本中分离出的金黄色葡萄球菌的非重复菌株。所有金黄色葡萄球菌分离株均按照CLSI指南采用Kirby Bauer圆盘扩散法在Mueller Hinton琼脂板上进行抗生素药敏试验。检测的抗生素包括青霉素(10U)、阿莫西林-克拉维酸(20/10μg)、磺胺甲恶唑-甲氧苄啶(1.25/23.75μg)、环丙沙星(5μg)、红霉素(15μg)、克林霉素(2μg)、万古霉素(30μg)、替柯planin (30μg)和利奈唑胺(30μg)。结果:本研究共处理临床标本23699份,其中鉴定出临床分离金黄色葡萄球菌1233株并进一步处理。临床标本中金黄色葡萄球菌检出最多的是化脓性标本(63.1%),其次是血液标本(29.9%)和尿液标本(4.8%)。住院患者中金黄色葡萄球菌感染的发生率为71.2%,高于门诊患者的28.8%。金黄色葡萄球菌的分离也存在季节变化,夏季获得的分离株百分比高于冬季。药敏试验中,49.6%的菌株耐甲氧西林。大多数菌株对青霉素(92.1%)耐药,其次是红霉素(59%)。对磺胺甲恶唑-甲氧苄啶耐药的占比接近一半(49.3%),其次是阿莫西林-克拉维酸(47.8%)、环丙沙星(43.4%)和克林霉素(18.4%)。所有菌株对万古霉素、替柯planin、利奈唑胺等抗生素均100%敏感。结论:鉴于本研究中抗生素耐药性的高流行率,有效治疗由多重耐药葡萄球菌菌株引起的感染可能变得具有挑战性。万古霉素、替柯普兰和利奈唑胺等药物有望成为对抗耐多药MRSA菌株的特效药,但我们需要保证明智地使用这些特效药,以保存它们以备将来使用。
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引用次数: 0
Assessment of Inter-Condylar Distance as a guide for Arrangement of Maxillary Prosthetic Teeth 评估髁间距离对上颌义齿排列的指导作用
Pub Date : 2021-01-29 DOI: 10.18311/IJMDS/2021/26378
P. Parajuli, P. Suwal, R. Singh
Background & Objectives: Inter-Condylar Distance (ICD) has been used as a reliable and fixed parameter for selection of mandibular anterior teeth and their arrangement. The objectives of this study were to determine the relationship of inter-condylar distance with maxillary inter-canine distance and maxillary inter-molar distance. Methods: This crosssectional study was conducted in the Department of Prosthodontics & Crown-Bridge, B.P. Koirala Institute of Health Sciences (BPKIHS) enrolling 120 dentate subjects those fulfilled the inclusion criteria. Maxillary casts were prepared and the distance between bilateral canine tips were measured using a Vernier caliper. The mesiobuccal cusp tips of maxillary first molars were marked and the distance was measured using the caliper. Inter-condylar distance was measured using arbritary face bow. The distance between the two condylar rods was measured in millimeters using Vernier caliper. Every distance was measured three times to assure the accuracy and mean taken. Data were recorded on the proforma for statistical analysis. Results: The ratio of intercondylar distance to the maxillary inter-canine distance was found to be 3.6:1 whereas that to intermolar distance was 2.6:1. Pearson correlation coefficients (r) for the ICD showed positive and significant correlation to both the inter-dental distances. (r - 0.33, (p<0.001) for Maxillary Inter-Canine distance (MIC) and r – 0.59, (p<0.001) for Maxillary Inter-Molar distance (MIM). Conclusion: Inter-condylar distance provides significant measurements and hence can be used as a guide for maxillary denture teeth arrangement.
背景与目的:髁间距离(ICD)是下颌前牙选择和排列的一个可靠、固定的参数。本研究的目的是确定髁间距离与上颌犬间距离和上颌磨牙间距离的关系。方法:本横断面研究在柯伊拉腊健康科学研究所(BPKIHS)修复与冠桥科进行,纳入120名符合纳入标准的有牙受试者。准备上颌铸型,用游标卡尺测量双牙尖之间的距离。标记上颌第一磨牙中颊尖尖,用卡尺测量距离。采用任意面弓测量髁间距离。用游标卡尺测量两髁棒之间的距离,以毫米为单位。每段距离测量三次,以保证测量的准确性和平均值。将数据记录在表格上进行统计分析。结果:髁间距离与上颌犬间距离之比为3.6:1,磨牙间距离之比为2.6:1。ICD的Pearson相关系数(r)与牙间距离均呈显著正相关。(r - 0.33, p<0.001)上颌犬齿间距离(MIC)和上颌磨牙间距离(MIM) r- 0.59, (p<0.001)。结论:髁间距离提供了重要的测量指标,可作为上颌义齿排列的指导。
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引用次数: 1
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International Journal of Medical and Dental Sciences
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