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The Ethics of Using “Pre-made Designs” in Commerce 商业中使用“预制设计”的伦理
Pub Date : 2023-06-05 DOI: 10.24940/ijird/2023/v12/i5/may23006
None Esseku, J. F., None Teye, V. Q. N., None Amissah, B, None Musa, M., None Opoku, N.
The distinction between creative work that is entirely original and that which is only based on the work of others is becoming increasingly difficult to discern as graphic design software gets easier to use and more widely available. This study examines the ethical consequences of utilizing graphic design software, particularly in regard to copyright legislation and responsible design practices. This article analyses how pre-made design components and templates found in software programmes might infringe on copyright and how designers can traverse these legal concerns to preserve ethical design practices. In addition, the essay explores the role that graphic design software may play in either nurturing or impeding original creativity, as well as the ethical issues that come into play when choosing between developing original ideas and employing pre-made design pieces. In conclusion, this section of the essay provides guidelines for designers on how they should approach the usage of graphic design tools in an ethical and responsible manner. This article gives insight into the ethical issues designers must consider while producing new designs and navigating the difficulties of copyright law by examining the ethical consequences of utilizing graphic design tools.
随着图形设计软件变得更容易使用和更广泛使用,完全原创的创造性作品和仅基于他人作品的创造性作品之间的区别正变得越来越难以辨别。本研究考察了使用图形设计软件的道德后果,特别是在版权立法和负责任的设计实践方面。本文分析了在软件程序中发现的预制设计组件和模板如何侵犯版权,以及设计师如何通过这些法律问题来维护合乎道德的设计实践。此外,本文探讨了平面设计软件在培养或阻碍原创创造力方面可能发挥的作用,以及在发展原创想法和采用预制设计作品之间进行选择时所起的道德问题。总之,本文的这一部分为设计师提供了指导方针,说明他们应该如何以道德和负责任的方式使用图形设计工具。本文通过研究使用图形设计工具的道德后果,深入了解设计师在制作新设计和导航版权法困难时必须考虑的道德问题。
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引用次数: 0
Effect of Civic Education on Effective Leadership and Sustainable Development 公民教育对有效领导和可持续发展的影响
Pub Date : 2023-05-29 DOI: 10.24940/ijird/2023/v12/i4/apr23018
Ejuchegahi A. Angwaomaodoko
This study examined how civic education affects both sustainable development and successful leadership. The goal of the study was to evaluate the role civic education played in sustainable development and the impact it has had in solving leadership problems currently occurring in many nations, regions, towns, organizations, and even religions around the globe. This research clarified the terms civic education, sustainable development, and leadership; it also looked at the connections between civic education and leadership, the effects of civic education on leadership qualities, and the connections between civic education and sustainable development. It became clear that the lack of civic education in schools is the cause of leadership problems at various levels and in different settings. It argued that the only answer to diverse leadership problems in different nations is political education. The various theories of leadership, which contends that meeting a group's needs and wants is the core of management, were used in the study to support our claims. According to this theory, a leader has only performed his duties well when he has contributed to the efficacy and group cohesiveness. Through televised public forums, print media, and television announcements, it is advised that the significance and effect of civic education on sustainable development, leadership, and good governance be consistently conveyed to students, undergraduates, and the public at large.
这项研究考察了公民教育如何影响可持续发展和成功的领导力。这项研究的目的是评估公民教育在可持续发展中所起的作用,以及它在解决目前在全球许多国家、地区、城镇、组织甚至宗教中出现的领导力问题方面所产生的影响。本研究厘清公民教育、永续发展与领导的概念;它还研究了公民教育与领导能力之间的联系,公民教育对领导素质的影响,以及公民教育与可持续发展之间的联系。很明显,学校缺乏公民教育是导致各级和不同环境下的领导问题的原因。它认为,解决不同国家的不同领导问题的唯一答案是政治教育。各种各样的领导理论都认为满足群体的需求和欲望是管理的核心,这些理论都被用于研究中来支持我们的观点。根据这一理论,领导者只有在为团队效能和团队凝聚力做出贡献时,才能很好地履行了自己的职责。通过电视公共论坛、平面媒体和电视公告,建议将公民教育在可持续发展、领导力和良好治理方面的重要性和作用始终传达给学生、本科生和广大公众。
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引用次数: 0
Adoption Strategy for Cloud Computing in Kenyan Research Institutions 肯尼亚研究机构的云计算采用策略
Pub Date : 2023-05-16 DOI: 10.24940/ijird/2023/v12/i2/feb23001
Asnath Nyachiro, Dr. Kennedy Ondimu, Dr. Gabriel Mafura
Cloud computing has transformed the aspect of distributed computing from many other prevailing methods by offering more unlimited benefits, like cutting down computing costs and allowing more capacity and agility. It is viewed as a game-changer in how information technology is provided since it allows computer resources like storage, processing capacity, network infrastructure, and applications to be offered as a service via the Internet. In business, it seems to have become strategic, with the potential for use in crucial parts of an organization's IT infrastructure, as it offers a potential alternative to traditional Enterprise Resource Planning (ERP) systems. Most Kenyan research institutes' systems experienced certain flaws and recognized incidents of system rigidity, which prevented these institutions from efficiently meeting their mandate, especially when they desired to access services from home via the Internet. The Research design that was utilized in the study was a survey research design. The study employed a systematic review approach that examined the current literature on cloud computing adoption strategy. The systematic literature review revealed that existing research was dominated by issues of the characteristics/peculiarities and IT environments of research institutions in Kenya and if they were amenable to cloud solutions, the current cloud computing technologies, adoption approaches and drivers fostering cloud computing and the adoption strategy that met the requirements for cloud computing for Kenyan research institutions. The present research was reviewed for knowledge gap identification purposes and future research opportunities. The researcher developed an adoption strategy favorable to research Institutions that was flexible to the provision of cloud computing resources, enhanced greater cloud computing efficiency, reduced capital expenditure in hardware and software and increased the performance of the research Institution's operations, provided the efficiency of data and information and supported the effectiveness of the management activities since the cloud strategies discussed did not promote cooperation, agility, scalability and flexibility and saving costs by using calculating resources efficiently and optimally. This study employed a purposive sampling approach that picked a sample size of twenty respondents from the KMFRI and related organizations. The analytical review of specifically identified studies exposed the kind of challenges that existed and gave an indication that cloud computing was applicable for Kenyan Research Institutions because of the organization size, possession of required skills to make use of cloud-based services, Government regulations, industry regulations and internal policies necessitated the move to cloud computing strategy. The cloud service providers have adequate capacity to run the services and are ready with the services they provide. Researchers noted that all the research Institu
云计算通过提供更多的无限好处(比如降低计算成本、允许更大的容量和灵活性)改变了分布式计算的许多其他流行方法。它被视为信息技术提供方式的游戏规则改变者,因为它允许通过Internet将存储、处理能力、网络基础设施和应用程序等计算机资源作为服务提供。在业务中,它似乎已经成为战略,具有在组织it基础设施的关键部分使用的潜力,因为它提供了传统企业资源规划(ERP)系统的潜在替代方案。大多数肯尼亚研究机构的系统都存在某些缺陷和公认的系统僵化事件,这使这些机构无法有效地履行其职责,特别是当它们希望通过互联网从家中获得服务时。本研究采用的研究设计为调查研究设计。该研究采用了一种系统的回顾方法,检查了当前关于云计算采用策略的文献。系统的文献综述显示,现有的研究主要集中在肯尼亚研究机构的特征/特点和IT环境以及它们是否适合云解决方案、当前的云计算技术、促进云计算的采用方法和驱动因素以及满足肯尼亚研究机构云计算需求的采用策略等问题上。回顾了目前的研究,以确定知识差距的目的和未来的研究机会。研究人员制定了有利于研究机构的采用策略,该策略灵活地提供云计算资源,提高了云计算效率,减少了硬件和软件的资本支出,提高了研究机构的运营绩效,提供了数据和信息的效率,并支持了管理活动的有效性,因为所讨论的云战略并没有促进合作、敏捷性、可伸缩性和灵活性,并通过有效和最佳地使用计算资源来节省成本。本研究采用了有目的的抽样方法,从KMFRI和相关组织中挑选了20名受访者。对具体确定的研究进行的分析审查揭示了存在的各种挑战,并指出云计算适用于肯尼亚研究机构,因为组织规模、拥有利用云服务所需的技能、政府法规、行业法规和内部政策都需要转向云计算战略。云服务提供商有足够的能力来运行服务,并为他们提供的服务做好了准备。研究人员指出,所有研究机构都有专门的信息通信技术人员和信息通信技术政策。高效的服务交付意味着可以随时随地从云端轻松访问任何研究信息。使用因子分析,各种研究结构(技术、内部和外部环境)的可变权重被用于制定云计算(ASCC)的采用策略。已制定战略的研究报告提出的建议表明,应进一步发展网络基础设施,使肯尼亚研究机构能够连接到高速互联网,以便共享信息,从而确保利用云计算服务高效地提供服务。该研究还建议肯尼亚各研究机构对其客户和供应商进行培训,使其了解如何利用云计算服务高效地提供服务,以及如何采用云计算战略以实现高效地提供服务。可以开展进一步相关研究的领域,以确定制定的采用战略对肯尼亚研究机构采用云计算的长期影响。此外,还可以进行进一步的研究,以确定如何改进肯尼亚研究中采用云计算的已制定的采用战略。
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引用次数: 0
WhatsApp Data Policy, Data Security and Users’ Vulnerability WhatsApp数据政策,数据安全和用户漏洞
Pub Date : 2023-05-16 DOI: 10.24940/ijird/2023/v12/i4/apr23021
Oluwaseun Oladeji Olaniyi, Dagogo Sopriala Omubo
Several regulatory agencies regulate companies that deal with users' data, but specifically in the UK, they are regulated by the European Union General Data Protection Regulation (GDPR). The techniques of handling and processing data, rights of users, sanctions for defaulters, and other regulating clauses are formulated and implemented by these agencies to minimize the exploitation of the masses. Data regulation and management are essential because companies managing users' data are expected to handle data with care, caution, and due diligence. However, WhatsApp (arguably the most powerful instant messaging application in use) has been involved repeatedly in several cases that compromised the security of its users’ data over the years. The platform has become a prime target and medium for predators (con artists, fraudsters) with intentions to access users' data (phone numbers, last seen, live location, and others) for vile purposes. These cases include leaked data that could be used for marketing purposes, phishing, impersonation, and fraud. This paper highlights recent cases of data security (data leakages) and privacy policies involving WhatsApp, examining the various issues that threaten WhatsApp users and make them vulnerable to exploiters, cybercrime, and con artists. It also considers how WhatsApp can protect its users against vulnerabilities. Also, the European Union GDPR was examined in line with WhatsApp's privacy policy to measure compliance with the regulation in light of recent data breaches.  
一些监管机构对处理用户数据的公司进行监管,但特别是在英国,它们受欧盟通用数据保护条例(GDPR)的监管。数据的处理和处理技术、用户的权利、违规者的处罚等规范条款由这些机构制定和执行,以尽量减少对群众的剥削。数据监管和管理至关重要,因为管理用户数据的公司应该谨慎、谨慎、尽职地处理数据。然而,WhatsApp(可以说是目前使用中功能最强大的即时通讯应用程序)多年来多次卷入危及用户数据安全的案件。这个平台已经成为骗子、诈骗者的主要目标和媒介,他们为了卑鄙的目的访问用户的数据(电话号码、最后一次露面、实时位置等)。这些情况包括可能用于营销目的、网络钓鱼、冒充和欺诈的泄露数据。本文重点介绍了最近涉及WhatsApp的数据安全(数据泄露)和隐私政策案例,研究了威胁WhatsApp用户的各种问题,并使他们容易受到剥削者、网络犯罪和骗子的攻击。它还考虑了WhatsApp如何保护其用户免受漏洞的侵害。此外,根据WhatsApp的隐私政策,根据最近的数据泄露事件,对欧盟GDPR进行了审查,以衡量是否遵守该法规。
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引用次数: 4
Synthesis and Evaluation of Alum Crystals from Waste Aluminum Foils in Turbid Water Treatment 废铝箔混浊水处理中明矾结晶的合成及评价
Pub Date : 2023-05-08 DOI: 10.54536/jir.v1i1.1528
O. H. Olabimtan, Oluyinka O Akinlotan, Joyce Omohu, M. K. Ukpong, Bayo H Yekeen
The disposal of waste aluminum foil is a significant environmental concern due to its non-biodegradable nature and potential to contaminate the surrounding ecosystem. In this study, we synthesized alum crystals from waste aluminum foil and evaluated their potential as an effective adsorbent for water treatment. The synthesis process involved the reaction of crushed aluminum foil with sulfuric acid and sodium hydroxide to form aluminum hydroxide, which was then converted to alum crystals through a precipitation reaction. Chemical tests were conducted to confirm the presence of different ions in alum solution and solid alum crystals. The tests showed the presence of sulfate ions, potassium ions, and aluminum ions. Additionally, the study examined the effect of different dosages (10 to 100 mg/l) of alum on turbidity removal (triplicate) in water, where increasing the alum dosage led to an increase in turbidity removal, but beyond a certain point, the marginal increase in turbidity removal diminished. A dosage of around 40–50 mg/L was established as optimal for achieving a balance between effective turbidity removal and cost-effective use of alum, using a quadratic relationship to model a non-linear relationship between turbidity removal and alum dosage. This study demonstrates the potential of waste aluminum foil as a valuable resource for the synthesis of alum crystals, which can be used as an effective adsorbent for water treatment. Using waste materials for the synthesis of value-added products not only helps reduce environmental pollution but also contributes to the development of sustainable technologies. The results of this study have significant implications for the development of cost-effective and environmentally sustainable solutions for water treatment.
废铝箔的处理是一个重要的环境问题,由于其不可生物降解的性质和潜在的污染周围的生态系统。本研究以废铝箔为原料合成明矾晶体,并评价其作为水处理的有效吸附剂的潜力。该合成工艺是将粉碎的铝箔与硫酸和氢氧化钠反应生成氢氧化铝,然后通过沉淀反应转化为明矾晶体。化学试验证实了明矾溶液和固体明矾晶体中存在不同的离子。试验表明,硫酸盐离子、钾离子和铝离子的存在。此外,本研究还考察了不同剂量(10 ~ 100 mg/l)明矾对水中除浊(三次)的影响,其中增加明矾的剂量会导致除浊的增加,但超过某一点,除浊的边际增加就会减少。通过使用二次关系来模拟浊度去除和明矾用量之间的非线性关系,确定了40-50 mg/L左右的用量是实现有效除浊和成本效益使用明矾之间平衡的最佳用量。该研究表明,废铝箔是一种合成明矾晶体的宝贵资源,可作为水处理的有效吸附剂。利用废料合成增值产品不仅有助于减少环境污染,而且有助于可持续技术的发展。本研究的结果对开发具有成本效益和环境可持续性的水处理解决方案具有重要意义。
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引用次数: 0
Comparative Analysis and Models for Losses in Electrical Energy in Low Voltage Devices 低压装置中电能损耗的比较分析与模型
Pub Date : 2023-05-07 DOI: 10.54536/jir.v1i1.1570
O. H. Olabimtan, Sani K Ahmed, F. O. Arowosere, Agbe N Ozogu Agbe N, Ejovwoke J Efetobor
Electrical energy losses in low-voltage devices can have a significant impact on the overall efficiency of an electrical system. In this research, a comprehensive comparative analysis of losses in electrical energy in low-voltage devices, including transformers, cables, and switchgear was presented. Experiments to measure the losses under varying operating conditions, such as loads, ambient temperatures, and frequencies were conducted. The data collected from the experiments were then analyzed to identify the major contributors to losses in each device with models for these devices to predict the losses accurately. The models were based on analytical and empirical approaches, considering various factors such as size, insulation type, and operating conditions. The models were validated using the data collected from the experiments, and the results showed good agreement between the predicted and measured losses. The findings show that losses in low-voltage devices depend on various factors and can be significant. Transformers losses due to hysteresis and eddy currents were found to be effective at high loads. In cables, losses were higher at higher frequencies due to skin and proximity effects. In switchgear, losses were dependent on the type of switch used. The models developed in this study can help in identifying the significant contributors to losses and predicting the overall efficiency of an electrical system. The results of this study can be used in the design and optimization of low-voltage devices to improve their efficiency and reduce energy losses which can lead to significant savings in energy costs and improve the overall sustainability of electrical systems.
低压设备中的电能损耗会对电气系统的整体效率产生重大影响。在这项研究中,对低压设备(包括变压器、电缆和开关柜)中的电能损耗进行了全面的比较分析。实验测量了不同工作条件下的损耗,如负载、环境温度和频率。然后分析从实验中收集的数据,以确定每个设备中损耗的主要贡献者,并为这些设备建立模型,以准确预测损耗。该模型基于分析和经验方法,考虑了各种因素,如尺寸,绝缘类型和运行条件。利用实验数据对模型进行了验证,结果表明预测损失与实测损失吻合较好。研究结果表明,低压器件的损耗取决于各种因素,并且可能是显著的。由于磁滞和涡流引起的变压器损耗在高负载下是有效的。在电缆中,由于趋肤效应和接近效应,损耗在更高的频率下更高。在开关设备中,损耗取决于所使用的开关类型。本研究中开发的模型可以帮助确定造成损失的重要因素,并预测电力系统的整体效率。本研究结果可用于低压设备的设计和优化,以提高其效率,减少能量损失,从而显著节省能源成本,提高电气系统的整体可持续性。
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引用次数: 0
Technical Report on Harmful Impact of Illegal Bunkering of Crude Oil on the People and Environment of the Igbomatoru Community, Bayelsa, Niger Delta, Nigeria 关于非法注油对尼日利亚尼日尔三角洲巴耶尔萨伊博马托鲁社区人民和环境有害影响的技术报告
Pub Date : 2023-05-07 DOI: 10.54536/jir.v1i1.1531
Ozogu A. Nanadeinboemi, O. H. Olabimtan, Ndubuisi C. Chukwurah
Nigeria is blessed with crude oil in an abundance, which makes it one of the largest oil producers in Africa. Illegal crude oil bunkering is a regular activity in the Niger Delta region in Nigeria. The trend of illegal bunkering of crude oil activities in the Niger Delta has turned out to be a key concern to the people, government, and the international body. This makes it deem fit to carry out an assessment of the continued negative impact of vandalism, crude oil theft, and illegal bunkering of oil production activities in the Igbomatoru community in Southern Ijaw Local Government Area (SILGA), Bayelsa, Niger Delta area. This report critically examines the negative impact of vandalism and crude oil theft, negative impacts of illegal bunkering of crude oil activities in the community, and finding lasting possible solution to the problem of illegal bunkering of crude oil in the Igbomotoru community. Based on the investigation, some recommendations have been made, including that the government should promote a kick-start of cellular refinery programme to close the refining gap with strong local participation, provide legitimate employment opportunities, make better use of surveillance techniques, youth empowerment programmes should be carried out through vocational training, government should clean-up the degraded sites, government should give free education for the youths and children in the community, and government ought to promptly arrest and prosecute offenders of crude oil theft.
尼日利亚拥有丰富的原油,这使其成为非洲最大的石油生产国之一。非法原油加注是尼日利亚尼日尔三角洲地区经常发生的活动。尼日尔三角洲非法原油加注活动的趋势已成为人民、政府和国际机构关注的一个关键问题。因此,有必要对尼日尔三角洲巴耶尔萨南部Ijaw地方政府地区(SILGA) Igbomatoru社区的破坏行为、原油盗窃和非法石油生产活动的持续负面影响进行评估。本报告批判性地审查了故意破坏和原油盗窃的负面影响,社区非法加油原油活动的负面影响,并为Igbomotoru社区非法加油原油问题找到持久的可能解决方案。根据调查,提出了一些建议,包括政府应该推动启动蜂窝炼油厂计划,以缩小当地参与的炼油差距,提供合法的就业机会,更好地利用监测技术,应该通过职业培训实施青年赋权计划,政府应该清理退化的地点,政府应该为社区的青少年和儿童提供免费教育,政府应该及时逮捕和起诉盗窃原油的罪犯。
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引用次数: 0
Photocatalytic Degradation of Toluene (Component of Crude Oil) Contaminated Water Using Titanium Dioxide Based Catalyst: A Review 二氧化钛基催化剂光催化降解原油组分甲苯污染水体的研究进展
Pub Date : 2023-05-03 DOI: 10.54536/jir.v1i1.1532
Ozogu A. Nanadeinboemi, O. O. Fasanya, Olusegun A. Ajayi, Adegboyega S. Olawale, M. S. Olakunle
Petroleum industry is one of the fastest growing industry in the world, and it contributes significantly to the profitable development in unindustrialized countries. The wastewater from a petroleum industry consist a wide variety of pollutants like petroleum hydrocarbons, mercaptans, oil and grease, benzene, toluene, ethylbenzene, xylene, phenol, ammonia, sulphide and other organic compounds etc. All these compounds are present as very complex form in discharged water of petroleum industry, which are harmful to the environment and human health directly or indirectly. Pollution of soil-water interface due to the release of hydrocarbons in environment is a major public health concern, and therefore, remediation of these pollutants is needed to reduce risk to human and environment. Various methods such as physical, chemical, biological, and Advanced oxidation processes (AOPs) methods are used to degrade these pollutants from wastewater. The conventional remediation methods can only change the phase of contaminants without destroying them, thereby leading to another pollution problem. This review paper highlights some current treatment methods of toluene contaminated water, and to introduce a proposed method that sought to develop an oleophilic and hydrophobic composite catalyst (ESA-TiO2-FeS2-Kenaf), that would harvest the toluene content, and simultaneously degrade the harvested toluene content using solar light as the energy source.
石油工业是世界上发展最快的工业之一,对非工业化国家的盈利性发展作出了重要贡献。石油工业废水中含有各种各样的污染物,如石油碳氢化合物、硫醇、油和油脂、苯、甲苯、乙苯、二甲苯、苯酚、氨、硫化物和其他有机化合物等。这些化合物都以非常复杂的形式存在于石油工业排放水中,直接或间接地对环境和人体健康造成危害。由于在环境中释放碳氢化合物而造成的土壤-水界面污染是一个重大的公共卫生问题,因此需要对这些污染物进行补救,以减少对人类和环境的风险。各种方法,如物理、化学、生物和高级氧化过程(AOPs)方法被用于从废水中降解这些污染物。传统的修复方法只能改变污染物的相,而不能破坏污染物,从而导致另一个污染问题。本文综述了目前处理甲苯污染水的几种方法,并介绍了一种利用太阳能作为能量源制备亲油疏水复合催化剂(esa - tio2 - fes2 -红麻)的方法,该方法既能收集甲苯,又能降解收集到的甲苯。
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引用次数: 2
Portrayal of Society through Sexist Lenses: Misrepresentation of Women in Business in Print Media in Lesotho 性别歧视镜头下的社会写照:莱索托印刷媒体对商界女性的歪曲
Pub Date : 2023-05-03 DOI: 10.54536/jir.v1i1.1342
Senate Rapitse, Tawanda Mukurunge, Takura Bhila
Reputation can build a person’s business profile to propel them to greater heights or ruin them and their business enterprise. The media can prop up a business or destroy it as perception carries value with customers. This study therefore sought to establish how the media in Lesotho gives coverage on female businesspeople in the country. The study interviewed women in business to solicit their opinions on how they benefit from how the local print media portray them.
声誉可以建立一个人的商业形象,推动他们达到更高的高度,也可以毁掉他们和他们的企业。媒体可以支撑一个企业,也可以摧毁它,因为感知对客户来说是有价值的。因此,这项研究试图确定莱索托的新闻媒介如何报道该国的女商人。该研究采访了商界女性,询问她们如何从当地印刷媒体对她们的描述中获益。
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引用次数: 0
Evaluation of the Nephroprotective and Hypoglycemic Effect of Aqueous Extract of Leaf and Root of Thaumatococcus danielli on Alloxan-Induced Diabetic Rats 牛链球菌叶、根水提物对四氧嘧啶诱导的糖尿病大鼠的保肾降糖作用
Pub Date : 2023-04-24 DOI: 10.24940/ijird/2023/v12/i3/oct22019
Salaudeen Ibrahim Aderemi, Dr. Olojo Folake O., Rasheed-Adeleke, Azeezat Ayannike, Onye Ihimi, Ogunbusola Sade G.
The management of diabetes without side effects is a major challenge affecting majorities of the world population, thus the constant search for alternative compounds from natural products. This study investigated the nephroprotective and the hypoglycemic effect of aqueous extract of the leaf and root of Thaumatococcus danielli (T. danielli). Rats were assigned to 9 groups (1-9) of four rats each. Each group was made diabetic using Alloxan (150 mg/kg/b.wt) except the control group. The treatment group received 0.5 ml of Metformin (150 mg/kg/b.wt,), 200 and 400 mg/kg/b.wt, of Thaumatococcus danielli aqueous extract of leaf, root, and mixture orally, respectively. After 14 days of treatment, animals were sacrificed, and blood and kidney samples were collected for further analysis. The lowest reduction in glucose level was 22.65%, which was observed in the diabetic group treated with 200 mg/kg aqueous leaf of T. danielli, while the highest decrease was observed to be 38.63% in the diabetic group treated with 400 mg/kg aqueous root of Thaumatococcus danielli. The diabetic control group had a significantly higher level of sodium and potassium ions. Little changes were observed in chloride, carbonate, and total protein level in the diabetic group compared to the control group; while urea and creatinine levels were higher. Histological alterations such as poor architecture, few collapsed renal tubules, and loss of luminar spaces were observed in control. From this study, it can be inferred that aqueous extracts of the leaves and roots of Thaumatococcus danielli and their combination have antihyperglycemic activity as well as modulating renal indices and diabetes-induced nephropathy.  
无副作用的糖尿病管理是影响世界上大多数人口的一项重大挑战,因此不断寻找天然产物中的替代化合物。本研究探讨了大牛黄球藻叶和根水提物对肾脏的保护作用和降血糖作用。将大鼠分为9组(1 ~ 9),每组4只。除对照组外,各组均采用四氧嘧啶(150 mg/kg/b.wt)致糖尿病。治疗组给予二甲双胍0.5 ml (150 mg/kg/b.wt,)、200、400 mg/kg/b。分别口服牛膝球藻叶水提物、根水提物和混合液。治疗14天后,处死动物,采集血液和肾脏样本作进一步分析。以200 mg/kg牛蹄草叶片处理的糖尿病组血糖降低率最低,为22.65%;以400 mg/kg牛蹄草根处理的糖尿病组血糖降低率最高,为38.63%。糖尿病对照组的钠离子和钾离子水平明显高于对照组。与对照组相比,糖尿病组氯离子、碳酸盐和总蛋白水平变化不大;而尿素和肌酐水平较高。在对照组中观察到组织学改变,如结构不良,少数肾小管塌陷和光空间丧失。从本研究可以推断,丹尼尔酒球菌叶和根的水提物及其组合具有降糖活性,并能调节肾脏指标和糖尿病肾病。
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International journal of innovative research and development
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