Pub Date : 2014-01-01DOI: 10.5455/jeim.180614.or.106
H. Avsever, K. Gündüz, K. Orhan, G. Canitezer, B. Piskin, M. Akyol
Objective: The aim of this study was to investigate the panoramic radiographic findings of totally and partially edentulous patients and to reveal the significant role of radiographic evaluations before prosthodontic treatment in a sample of Turkish population. Methods: A total of 845 patients referred to our hospital for removable dentures were selected. All of the patients were totally or partially edentulous. The patients had clinical and radiographic examinations. All of the radiographs were evaluated for significant radiographic findings as follows: retained root fragments, embedded teeth, radio-lucencies, radio-opacities, maxillary sinus position and the location of the mental foramen. The obtained data were analyzed using descriptive statistics. Results: Positive radiographic findings were found in 40.47% of the patients who referred for removable prosthesis. Totally 84 retained roots were found in 74 patients; 64 (%76.2) of them have only one, and 10 (%11.9) have two retained roots. A total of 49 impacted teeth were found in 42 patients. According to our evaluation, 4.1% of patients (n = 35; female 17, male 18) have one; 0.8% of patients (n = 7; female 3, male 4) have two embedded teeth. Migrated sinus floor to the alveolar ridge was the most observed finding (37.5%), followed by resorption of alveolar ridge (4.5% of the patients, n = 38) in mental region. Moreover, 16 soft tissue calcifications, 12 osteosclerosis and 11 foreign bodies were found. Conclusions: Radiographic examination is crucial for pre-prosthetic evaluation on partially or totally edentulous patients that should considered as the first step to avoid the repetition of prosthetic rehabilitation, time waste, prestige loss and high treatment costs.
{"title":"Prevalence of edentulousness, prosthetic need and panoramic radiographic findings of totally and partially edentulous patients in a sample of Turkish population -","authors":"H. Avsever, K. Gündüz, K. Orhan, G. Canitezer, B. Piskin, M. Akyol","doi":"10.5455/jeim.180614.or.106","DOIUrl":"https://doi.org/10.5455/jeim.180614.or.106","url":null,"abstract":"Objective: The aim of this study was to investigate the panoramic radiographic findings of totally and partially edentulous patients and to reveal the significant role of radiographic evaluations before prosthodontic treatment in a sample of Turkish population. Methods: A total of 845 patients referred to our hospital for removable dentures were selected. All of the patients were totally or partially edentulous. The patients had clinical and radiographic examinations. All of the radiographs were evaluated for significant radiographic findings as follows: retained root fragments, embedded teeth, radio-lucencies, radio-opacities, maxillary sinus position and the location of the mental foramen. The obtained data were analyzed using descriptive statistics. Results: Positive radiographic findings were found in 40.47% of the patients who referred for removable prosthesis. Totally 84 retained roots were found in 74 patients; 64 (%76.2) of them have only one, and 10 (%11.9) have two retained roots. A total of 49 impacted teeth were found in 42 patients. According to our evaluation, 4.1% of patients (n = 35; female 17, male 18) have one; 0.8% of patients (n = 7; female 3, male 4) have two embedded teeth. Migrated sinus floor to the alveolar ridge was the most observed finding (37.5%), followed by resorption of alveolar ridge (4.5% of the patients, n = 38) in mental region. Moreover, 16 soft tissue calcifications, 12 osteosclerosis and 11 foreign bodies were found. Conclusions: Radiographic examination is crucial for pre-prosthetic evaluation on partially or totally edentulous patients that should considered as the first step to avoid the repetition of prosthetic rehabilitation, time waste, prestige loss and high treatment costs.","PeriodicalId":16091,"journal":{"name":"Journal of Experimental and Integrative Medicine","volume":"127 1","pages":"220-226"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84010629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2014-01-01DOI: 10.5455/JEIM.060114.ED.018
S. Oter, George Ellington
In October 2013, John Bohannon, contributing correspondent of Science Magazine, published an intriguing work regarding the peer-review process of scientific open access journals, which attracted much attention around the globe. In brief, with the help of a professional team mainly based in Harvard University, he concocted analogous fake articles reporting anticancer effects of a chemical extracted from a lichen species. The articles contain major flaws in the study design and methodology, along with glaring mistakes in the presentation of results, and they end with irrelevant conclusions that should have led to their rejection after a quick editorial check. And yet, more than half of the 304 open access journals...
{"title":"Universal ethics in scientific publishing","authors":"S. Oter, George Ellington","doi":"10.5455/JEIM.060114.ED.018","DOIUrl":"https://doi.org/10.5455/JEIM.060114.ED.018","url":null,"abstract":"In October 2013, John Bohannon, contributing correspondent of Science Magazine, published an intriguing work regarding the peer-review process of scientific open access journals, which attracted much attention around the globe. In brief, with the help of a professional team mainly based in Harvard University, he concocted analogous fake articles reporting anticancer effects of a chemical extracted from a lichen species. The articles contain major flaws in the study design and methodology, along with glaring mistakes in the presentation of results, and they end with irrelevant conclusions that should have led to their rejection after a quick editorial check. And yet, more than half of the 304 open access journals...","PeriodicalId":16091,"journal":{"name":"Journal of Experimental and Integrative Medicine","volume":"5 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81453458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2014-01-01DOI: 10.5455/JEIM.260214.OR.097
O. K. Olaibi, O. Ijomone, I. Olawuni, S. O. Adewole, S. O. Akinsomisoye
Objective: The mechanism of ethanol-induced gastrointestinal mucosal lesions is known to include direct damage to mucus synthesis. The present study histochemically evaluated the activity of mucus secreting cells and determined the concentration of nitric oxide (NO) in ethanol injured pylorus and duodenum of rats pretreated with ethanol extract of Moringa oleifera (MO) leaves. Methods: Male adult rats were randomly assigned into five groups: group A served as control; group B received single dose of 5 ml/kg ethanol orally; group C received 200 mg/kg MO only orally for five days; group D and E received MO at 200 mg/kg and cimetidine at 100 mg/kg orally for five days, respectively, and then ethanol was administered at 5 ml/kg orally on the 6th day to these groups. Results: Ethanol significantly reduced NO concentration in pylorus, and this was attenuated with MO pretreatment. Pretreatment with both MO and cimetidine significantly attenuated the hemorrhagic injuries induced by ethanol. Pretreatment with MO increased activity of mucus secreting cells compared to ethanol only group. Conclusion: The present study demonstrated that the antiulcer activity of Moringa oleifera may be attributed to preservation of mucus secreting cells and maintenance of endogenous NO concentrations in ethanol injured gastroduodenal tissues.
{"title":"Mucus secreting activity and nitric oxide concentrations of ethanol-injured pylorus and duodenum of rats pretreated with Moringa oleifera -","authors":"O. K. Olaibi, O. Ijomone, I. Olawuni, S. O. Adewole, S. O. Akinsomisoye","doi":"10.5455/JEIM.260214.OR.097","DOIUrl":"https://doi.org/10.5455/JEIM.260214.OR.097","url":null,"abstract":"Objective: The mechanism of ethanol-induced gastrointestinal mucosal lesions is known to include direct damage to mucus synthesis. The present study histochemically evaluated the activity of mucus secreting cells and determined the concentration of nitric oxide (NO) in ethanol injured pylorus and duodenum of rats pretreated with ethanol extract of Moringa oleifera (MO) leaves. Methods: Male adult rats were randomly assigned into five groups: group A served as control; group B received single dose of 5 ml/kg ethanol orally; group C received 200 mg/kg MO only orally for five days; group D and E received MO at 200 mg/kg and cimetidine at 100 mg/kg orally for five days, respectively, and then ethanol was administered at 5 ml/kg orally on the 6th day to these groups. Results: Ethanol significantly reduced NO concentration in pylorus, and this was attenuated with MO pretreatment. Pretreatment with both MO and cimetidine significantly attenuated the hemorrhagic injuries induced by ethanol. Pretreatment with MO increased activity of mucus secreting cells compared to ethanol only group. Conclusion: The present study demonstrated that the antiulcer activity of Moringa oleifera may be attributed to preservation of mucus secreting cells and maintenance of endogenous NO concentrations in ethanol injured gastroduodenal tissues.","PeriodicalId":16091,"journal":{"name":"Journal of Experimental and Integrative Medicine","volume":"129 1","pages":"123-130"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75483581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2014-01-01DOI: 10.5455/JEIM.060113.HP.011
M. Irmak
Virgin Mary gave birth to Jesus without a father. A scenario is presented here for this miraculous event. She is a chimera of 46,XX/46,XY type resulting from the fusion of two embryos of different sex types and both ovary and testis develop in Her body. It is well known that in chimera XX cells tend to gather on the left side while XY cells on the right; therefore, an ovary develops at the left side with an oviduct and a testis develops at the right side of the abdominal cavity with no duct. Both gonads are functional and produce oocyte and spermatozoa respectively after puberty. At the time of ovulation, estrogens leads to a negative pressure in the left oviduct and this vacuum effect helps oocyte and sperms to be picked-up into the tube, taking both types of gametes to the fertilization site in the left oviduct. Because of the higher temperature of the oocyte at the left ovary, fertilization occurs with a Y-bearing sperm to give rise to a XY male embryo which becomes miraculously Jesus.
{"title":"Embryological basis of the virgin birth of Jesus","authors":"M. Irmak","doi":"10.5455/JEIM.060113.HP.011","DOIUrl":"https://doi.org/10.5455/JEIM.060113.HP.011","url":null,"abstract":"Virgin Mary gave birth to Jesus without a father. A scenario is presented here for this miraculous event. She is a chimera of 46,XX/46,XY type resulting from the fusion of two embryos of different sex types and both ovary and testis develop in Her body. It is well known that in chimera XX cells tend to gather on the left side while XY cells on the right; therefore, an ovary develops at the left side with an oviduct and a testis develops at the right side of the abdominal cavity with no duct. Both gonads are functional and produce oocyte and spermatozoa respectively after puberty. At the time of ovulation, estrogens leads to a negative pressure in the left oviduct and this vacuum effect helps oocyte and sperms to be picked-up into the tube, taking both types of gametes to the fertilization site in the left oviduct. Because of the higher temperature of the oocyte at the left ovary, fertilization occurs with a Y-bearing sperm to give rise to a XY male embryo which becomes miraculously Jesus.","PeriodicalId":16091,"journal":{"name":"Journal of Experimental and Integrative Medicine","volume":"36 1","pages":"143-146"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74044961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2014-01-01DOI: 10.5455/JEIM.021113.HP.008
M. Irmak
Received September 19, 2013 Accepted November 2, 2013 Published Online December 16, 2013 DOI 10.5455/jeim.021113.hp.008 Corresponding Author M.Kemal Irmak Gulhane Askeri Tip Akademisi Yuksek Bilim Konseyi 06010 Etlik, Ankara, Turkey. mkirmak@gata.edu.tr
{"title":"Evolution or adaptation? What do heritable adaptive changes imply?","authors":"M. Irmak","doi":"10.5455/JEIM.021113.HP.008","DOIUrl":"https://doi.org/10.5455/JEIM.021113.HP.008","url":null,"abstract":"Received September 19, 2013 Accepted November 2, 2013 Published Online December 16, 2013 DOI 10.5455/jeim.021113.hp.008 Corresponding Author M.Kemal Irmak Gulhane Askeri Tip Akademisi Yuksek Bilim Konseyi 06010 Etlik, Ankara, Turkey. mkirmak@gata.edu.tr","PeriodicalId":16091,"journal":{"name":"Journal of Experimental and Integrative Medicine","volume":"24 1","pages":"13-16"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89403626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2014-01-01DOI: 10.5455/JEIM.260214.BR.019
S. Mostovoy, V. F. Shul’gin, E. Maksimova, I. Nauhatsky, Elena T. Melucova, Kristina A. Plehanova
{"title":"Mineralizing process and morphological structure of the femoral bone in rats under influence of aminophosphonates","authors":"S. Mostovoy, V. F. Shul’gin, E. Maksimova, I. Nauhatsky, Elena T. Melucova, Kristina A. Plehanova","doi":"10.5455/JEIM.260214.BR.019","DOIUrl":"https://doi.org/10.5455/JEIM.260214.BR.019","url":null,"abstract":"","PeriodicalId":16091,"journal":{"name":"Journal of Experimental and Integrative Medicine","volume":"64 1","pages":"81-84"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73605924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2014-01-01DOI: 10.5455/JEIM.240614.OR.107
A. Padmaja, A. Sultana, Khaleequr Rahman, Sumana Nagapattinam
Objective: To investigate and compare the efficacy of oleo-gum-resin of root of Cyperus scariosus and Boswellia serrata with placebo in improving health related quality of life (HRQOL) in women with stress urinary incontinence (SUI). Methods: A parallel, randomized placebo-controlled, single-blind, pre- and post-test trial was conducted in the National Institute of Unani Medicine Hospital. The patients (n = 60) were randomly allocated to either test (n = 30) or control group (n = 30). In the test and placebo group, equal quantity of C.scariosus and B.serrata (4 g powder in two divided doses) plus pelvic floor muscle training (PFMT) and placebo plus PFMT, respectively, was given for 8 weeks. The outcome was to assess HRQOL by International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF). Mann-Whitney, Wilcoxon Matched paired, Chi-square or Fisher Exact tests were used to analyze the results. Results: The mean ICIQ-SF score in the test and control group at baseline was 10.2 ± 0.96 and 10.13 ± 0.89 respectively. At post-intervention, statistically significant improvement was recorded in the ICIQ-SF scores between groups. In addition, within the group comparison was statistically significant in both groups at each follow up. The percentage improvement from baseline at 12 weeks was 70% and 53% in the test and control groups, respectively. No adverse effects were noted. Conclusion: The test group yielded a more positive effect with regards to improvement in HRQOL than control group in women with stress urinary incontinence. Hence, test drugs plus PFMT appear to be a better alternative than PFMT alone.
{"title":"Effectiveness of Cyperus scariosus and Boswellia serrata on quality of life in women with stress urinary incontinence assessed with ICIQ-SF -","authors":"A. Padmaja, A. Sultana, Khaleequr Rahman, Sumana Nagapattinam","doi":"10.5455/JEIM.240614.OR.107","DOIUrl":"https://doi.org/10.5455/JEIM.240614.OR.107","url":null,"abstract":"Objective: To investigate and compare the efficacy of oleo-gum-resin of root of Cyperus scariosus and Boswellia serrata with placebo in improving health related quality of life (HRQOL) in women with stress urinary incontinence (SUI). Methods: A parallel, randomized placebo-controlled, single-blind, pre- and post-test trial was conducted in the National Institute of Unani Medicine Hospital. The patients (n = 60) were randomly allocated to either test (n = 30) or control group (n = 30). In the test and placebo group, equal quantity of C.scariosus and B.serrata (4 g powder in two divided doses) plus pelvic floor muscle training (PFMT) and placebo plus PFMT, respectively, was given for 8 weeks. The outcome was to assess HRQOL by International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF). Mann-Whitney, Wilcoxon Matched paired, Chi-square or Fisher Exact tests were used to analyze the results. Results: The mean ICIQ-SF score in the test and control group at baseline was 10.2 ± 0.96 and 10.13 ± 0.89 respectively. At post-intervention, statistically significant improvement was recorded in the ICIQ-SF scores between groups. In addition, within the group comparison was statistically significant in both groups at each follow up. The percentage improvement from baseline at 12 weeks was 70% and 53% in the test and control groups, respectively. No adverse effects were noted. Conclusion: The test group yielded a more positive effect with regards to improvement in HRQOL than control group in women with stress urinary incontinence. Hence, test drugs plus PFMT appear to be a better alternative than PFMT alone.","PeriodicalId":16091,"journal":{"name":"Journal of Experimental and Integrative Medicine","volume":"78 1","pages":"212-219"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76116560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2014-01-01DOI: 10.5455/JEIM.291213.HP.010
M. Irmak
Brain is protected from thermal damage by a so-called radiator system: the brain cooling system. As the brain gets hotter, the veins of this radiator system bring in cool blood from the evaporating surfaces of skin and craniofacial cavities. The craniofacial regions important in brain cooling system are very similar to the regions washed or wetted with ablution. So washing the face, oral and nasal cavities, and wetting scalp, ears and nape 4-5 times a day help the brain to remain cool throughout the day. This obviously means that with ablution cooler the head, healthier the brain. However, when a person is erect, the basal surface of the brain is in close contact with the cranial bones and therefore cerebrospinal fluid (CSF) could not cool the basal parts of the brain in erect position. Of course the relations of CSF to the skull and the brain are reversed when a person stoops (such as bowing and prostrating) allowing the CSF to intervene between the brain and the skull. Therefore stooping (as Muslims do about 120 times a day with prayer) would be beneficial for cooling the brain entirely by providing the CSF to wash-up the basal parts of brain. As for the other benefits of prayer, grounding is another aspect which provides a basis that restores and maintains natural electrical contact between the human body and the earth.
{"title":"Medical aspects of ablution and prayer","authors":"M. Irmak","doi":"10.5455/JEIM.291213.HP.010","DOIUrl":"https://doi.org/10.5455/JEIM.291213.HP.010","url":null,"abstract":"Brain is protected from thermal damage by a so-called radiator system: the brain cooling system. As the brain gets hotter, the veins of this radiator system bring in cool blood from the evaporating surfaces of skin and craniofacial cavities. The craniofacial regions important in brain cooling system are very similar to the regions washed or wetted with ablution. So washing the face, oral and nasal cavities, and wetting scalp, ears and nape 4-5 times a day help the brain to remain cool throughout the day. This obviously means that with ablution cooler the head, healthier the brain. However, when a person is erect, the basal surface of the brain is in close contact with the cranial bones and therefore cerebrospinal fluid (CSF) could not cool the basal parts of the brain in erect position. Of course the relations of CSF to the skull and the brain are reversed when a person stoops (such as bowing and prostrating) allowing the CSF to intervene between the brain and the skull. Therefore stooping (as Muslims do about 120 times a day with prayer) would be beneficial for cooling the brain entirely by providing the CSF to wash-up the basal parts of brain. As for the other benefits of prayer, grounding is another aspect which provides a basis that restores and maintains natural electrical contact between the human body and the earth.","PeriodicalId":16091,"journal":{"name":"Journal of Experimental and Integrative Medicine","volume":"33 1","pages":"147-149"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77308197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}