Pub Date : 2024-02-29DOI: 10.55522/jmpas.v13i1.5890
Elmiawati Latifah
Purslane plant (Portulaca oleracea L.) is a type of wild plant that grows abundantly, but its benefits are rarely known. Purslane contains saponins, which have high antioxidant and biological activity. Skin that is sensitive to sun exposure is the issue this nanospray is targeting. The aim of this research is to determine the optimal formulation of herbal nanospray products with Purslane sunscreen to treat skin problems caused by sun exposure. The research method used was an experimental method with research stages starting from plant determination, extract making, nanospray formulation determination, preparation evaluation, in vivo UV protection activity test, and in vitro SPF test. Quantitative descriptive analysis was carried out using Microsoft Excel and SPSS Version 24. There were significant differences in erythema (lesions on the skin) between the 4 treatment groups, with significant differences in the negative control and positive control groups, as well as the group given dose treatment (the amount of extract in the nanoparticles) of 0.8 g and 0.4 g of purslane extract with the negative control. So, it can be concluded that doses of 0.8 g (SPF value: 9.9) and 0.4 g (SPF value: 8.43) of purslane extract have the potential to be sunscreens with maximum category and extra protective power. Purslane extract nanospray sunscreen has the advantage of being made from herbal ingredients, which have less potential for irritation than chemical sunscreen products.
{"title":"Formulation of nano spray preparation from Purslane Leaf Extract (Portulaca\u0000 oleracea l.) as sunscreen","authors":"Elmiawati Latifah","doi":"10.55522/jmpas.v13i1.5890","DOIUrl":"https://doi.org/10.55522/jmpas.v13i1.5890","url":null,"abstract":"Purslane plant (Portulaca oleracea L.) is a type of wild plant that grows\u0000 abundantly, but its benefits are rarely known. Purslane contains saponins, which have\u0000 high antioxidant and biological activity. Skin that is sensitive to sun exposure is the\u0000 issue this nanospray is targeting. The aim of this research is to determine the optimal\u0000 formulation of herbal nanospray products with Purslane sunscreen to treat skin problems\u0000 caused by sun exposure. The research method used was an experimental method with\u0000 research stages starting from plant determination, extract making, nanospray formulation\u0000 determination, preparation evaluation, in vivo UV protection activity test, and in vitro\u0000 SPF test. Quantitative descriptive analysis was carried out using Microsoft Excel and\u0000 SPSS Version 24. There were significant differences in erythema (lesions on the skin)\u0000 between the 4 treatment groups, with significant differences in the negative control and\u0000 positive control groups, as well as the group given dose treatment (the amount of\u0000 extract in the nanoparticles) of 0.8 g and 0.4 g of purslane extract with the negative\u0000 control. So, it can be concluded that doses of 0.8 g (SPF value: 9.9) and 0.4 g (SPF\u0000 value: 8.43) of purslane extract have the potential to be sunscreens with maximum\u0000 category and extra protective power. Purslane extract nanospray sunscreen has the\u0000 advantage of being made from herbal ingredients, which have less potential for\u0000 irritation than chemical sunscreen products.","PeriodicalId":16445,"journal":{"name":"Journal of Medical pharmaceutical and allied sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140411658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}