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2019 International Conference on Advanced Computer Science and information Systems (ICACSIS)最新文献

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Prediction of Drug-Target Interaction on Jamu Formulas using Machine Learning Approaches 利用机器学习方法预测Jamu公式的药物-靶标相互作用
Pub Date : 2019-10-01 DOI: 10.1109/ICACSIS47736.2019.8979795
A. K. Nasution, S. Wijaya, W. Kusuma
Jamu is an Indonesian herbal medicine that has many benefits. Prediction of drug-target interactions on Jamu formula using a graph-based approach was carried out, but the results were unsatisfactory with the area under the precision-recall curve (AUPR) of 0.70. This study develops a prediction model of drug-target interactions with machine learning approach using Support Vector Machine (SVM) and Random Forest (RF). The dataset used in this study as the same as the dataset in the previous research, obtained from Indonesian Jamu Herbs (IJAH) Analytics. The dataset represents interactions of compounds and proteins, including labels to indicate those of interactions. Principal Component Analysis (PCA) is used as feature reduction in the pre-processing stage. The prediction models using SVM and RF combined with PCA obtain the best AUPR results of 0.99. These results indicate that the machine learning approach has better performance than those of the graph-based approach in predicting drug-target interactions on Jamu formulas.
Jamu是一种印尼草药,有很多好处。采用基于图的方法对药物-靶标相互作用进行了预测,但结果并不理想,精确召回曲线下面积(AUPR)为0.70。本研究利用支持向量机(SVM)和随机森林(RF)的机器学习方法建立了药物-靶标相互作用的预测模型。本研究中使用的数据集与先前研究中的数据集相同,来自印度尼西亚Jamu Herbs (IJAH) Analytics。该数据集表示化合物和蛋白质的相互作用,包括指示这些相互作用的标签。预处理阶段采用主成分分析(PCA)进行特征约简。采用SVM和RF结合主成分分析的预测模型得到的AUPR为0.99的最佳结果。这些结果表明,机器学习方法比基于图的方法在预测Jamu公式上的药物-靶标相互作用方面具有更好的性能。
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引用次数: 6
ICACSIS 2019 Authors Index ICACSIS 2019作者索引
Pub Date : 2019-10-01 DOI: 10.1109/icacsis47736.2019.8979694
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引用次数: 0
The impact of feature selection methods on machine learning-based docking prediction of Indonesian medicinal plant compounds and HIV-1 protease 特征选择方法对基于机器学习的印尼药用植物化合物与HIV-1蛋白酶对接预测的影响
Pub Date : 2019-10-01 DOI: 10.1109/ICACSIS47736.2019.8979672
Rahman Pujianto, Yohanes Gultom, A. Wibisono, Arry Yanuar, H. Suhartanto
This work evaluates usage feature selection methods to reduce the number of features required to predict docking results between Indonesian medicinal plant compounds and HIV protease. Two feature selection methods, Recursive Feature Elimination (RFE) and Wrapper Method (WM), are trained with a dataset of 7,330 samples and 667 features from PubChem Bioassay and DUD-E decoys. To evaluate the selected features, a dataset of 368 Indonesian herbal chemical compounds labeled by manually docking to PDB HIV-1 protease is used to benchmark the performance of linear SVM classifier using different sets of features. Our experiments show that a set of 471 features selected by RFE and 249 by WM achieve a reduction of classification time by 4.0 and 8.2 seconds respectively. Although the accuracy and sensitivity are also increased by 8% and 16%, no meaningful improvement observed for precision and specificity.
这项工作评估了使用特征选择方法,以减少预测印度尼西亚药用植物化合物与HIV蛋白酶之间对接结果所需的特征数量。两种特征选择方法,递归特征消除(RFE)和包装方法(WM),使用来自PubChem Bioassay和ddu - e诱饵的7,330个样本和667个特征的数据集进行训练。为了评估所选择的特征,使用368个印度尼西亚草药化合物的数据集,通过人工对接PDB HIV-1蛋白酶进行标记,对使用不同特征集的线性支持向量机分类器的性能进行基准测试。我们的实验表明,RFE选择471个特征集,WM选择249个特征集,分类时间分别减少4.0秒和8.2秒。虽然准确度和灵敏度也分别提高了8%和16%,但在精密度和特异性方面没有明显的提高。
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引用次数: 0
Strategies to Improve Performance of Convolutional Neural Network on Histopathological Images Classification 改进卷积神经网络在组织病理图像分类中的性能策略
Pub Date : 2019-10-01 DOI: 10.1109/ICACSIS47736.2019.8979740
Toto Haryanto, H. Suhartanto, A. Murni, K. Kusmardi
Convolutional Neural Network (CNN) has been widely used in medical image processing. Histopathology is one of modality or images for a pathologist to analyze the status of cancer. The unstructured pattern of this image cause the problem, tend to miss identification or takes more time to analyze by the pathologist. Besides that, Deep learning training generally requires powerful hardware resources to improve performance during the training. Therefore, to address these problems, we propose two main activities in this study; to accelerate training time and to enhance the histopathology dataset. We train our CNN on three similar GPU specification (GTX-1080) as an alternative to become training time is faster. Mean-shift filter is one of the low-pass filter technique. We use this to handle unstructured pattern on histopathology images to enhance this dataset. The performance of all three GPUs is presented during the training process with 500 epochs measure by the speedup. Meanwhile, the performance of model testing is carried out with several batch-size selection scenarios from 32,64,128 and 256. The use of mean-shift can improve convergence during training in 128 batch-size become faster.
卷积神经网络(CNN)在医学图像处理中得到了广泛的应用。组织病理学是病理学家分析肿瘤状态的一种方式或图像。该图像的非结构化模式导致了问题,往往无法识别或需要更多的时间来分析病理学家。此外,深度学习训练通常需要强大的硬件资源来提高训练过程中的性能。因此,为了解决这些问题,我们在本研究中提出了两个主要活动;加快训练时间,增强组织病理学数据集。我们在三种类似的GPU规格(GTX-1080)上训练CNN,作为训练时间更快的替代方案。均值移位滤波器是低通滤波技术的一种。我们使用它来处理组织病理学图像上的非结构化模式,以增强该数据集。在训练过程中,三种gpu的性能以500次加速度量。同时,在32,64,128和256个批大小选择场景下进行了模型性能测试。使用mean-shift可以提高训练过程中的收敛性,在128批大小的训练中变得更快。
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引用次数: 5
A study of analogical grids extracted using feature vectors on varying vocabulary sizes in Indonesian 印尼语不同词汇量下特征向量提取的类比网格研究
Pub Date : 2019-10-01 DOI: 10.1109/ICACSIS47736.2019.8979864
Rashel Fam, Y. Lepage
Indonesian as an agglutinating language is known for its derivative morphological richness. Word forms are constructed by combining stem and affixes. In this paper, we study the influence of surface form and morphological information in analogical grids extracted from a set of word forms with varying sizes. Each word form is represented as a feature vector. In the experiment setting, we consider three features: characters, affixes, and morphosyntactic definition. The sizes and saturation are then observed to characterize the extracted grids.
印尼语作为一种粘连语,以其丰富的词源而闻名。词形是由词干和词缀组合而成的。在本文中,我们研究了从一组不同大小的词形式中提取的类比网格中表面形式和形态信息的影响。每个词的形式被表示为一个特征向量。在实验设置中,我们考虑了三个特征:字符、词缀和形态句法定义。然后观察大小和饱和度来表征提取的网格。
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引用次数: 0
Flavonoid Distribution Mapping System of Velvet Apple Leaf Based on Hyperspectral Imaging 基于高光谱成像的丝绒苹果叶片类黄酮分布制图系统
Pub Date : 2019-10-01 DOI: 10.1109/ICACSIS47736.2019.8979775
Maulana Ihsan, A. H. Saputro, W. Handayani
The total content of flavonoids in plants is generally measured using spectrophotometric analysis based on color absorption rates. The method could not inform the distribution of flavonoids in a leaf. In this study, the mapping system of flavonoid distribution of Velvet Apple (Diospyros discolor Willd.) leaf was introduced using a hyperspectral imaging technique combining spectral and spatial analysis. The proposed system consists of a measurement system and a mathematical model that converts each spatial pixel into a value that represents the number of flavonoids in velvet apple leaves. The measurement system consists of a hyperspectral camera, halogen lamp, slider, and measurement frame. A random forest (RF) method is used to calculate the transformation model between reflectance values and total flavonoids. The construction of the measurement system was carried out with 738 data containing spectral data and lab measurement data. The evaluation of the random forest model obtained a value of R2 of 0.94 and RMSE 15.87 mg/ml.
植物中黄酮类化合物的总含量通常采用基于显色吸收率的分光光度法测定。该方法不能反映黄酮类化合物在叶片中的分布。本研究采用光谱与空间分析相结合的高光谱成像技术,建立了丝绒苹果叶片黄酮类化合物分布图谱。该系统由一个测量系统和一个数学模型组成,该模型将每个空间像素转换为代表天鹅绒苹果叶片中黄酮类化合物数量的值。测量系统由高光谱相机、卤素灯、滑块和测量框架组成。采用随机森林(RF)方法计算反射率值与总黄酮之间的转换模型。测量系统的构建使用了738个数据,其中包括光谱数据和实验室测量数据。随机森林模型的评价R2为0.94,RMSE为15.87 mg/ml。
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引用次数: 2
The Implementation of Data Mining to Show UKT (Students’ Tuition) Using Fuzzy C-Means Algorithm : (Case Study: Universitas Pendidikan Ganesha) 使用模糊c均值算法实现UKT(学生学费)数据挖掘(以Universitas Pendidikan Ganesha为例)
Pub Date : 2019-10-01 DOI: 10.1109/ICACSIS47736.2019.8979933
Nengah Widya Utami, I. N. Sukajaya, I. Candiasa, Eka Grana Aristyana Dewi
This research aimed to show the result of clustering students’ tuition (UKT) at Undiksha using algorithm FCM. The characteristics of each cluster, measurement of level implementing algorithm FCM accuracy in determining UKT. Students’ tuition data used in this research include students’ tuition from SBMPTN year 2017. The students’ data came from 30 students with 7 parameters, namely, parents’ occupation, parents’ income, number of dependents, assets, water payment, electronic voltage, and varieties of vehicles. The data of students’ tuition grouped into four groups, namely, UKT 1, UKT 2, UKT 3, and UKT 4. The data from grouping students’ tuition using FCM method in determining students’ tuition supported with Matlab Software 2017 a showed UKT 1 into 89 students, UKT 2 into 91 students, UKT 3 into 79 students, and UKT 4 into 46 students. The data characteristics of each student’s tuition were gathered from each parameter based on the result of the center vector (v) in the last iteration. Besides, the result showed an FCM method has high accuracy in 0.78. The result of factor analysis showed 3 factors determined students’ tuition from 7 parameters, namely, income factor, expulsion factor, and load factor. On the other hand, future research can be developed by grouping the 3 factors as computation variable in algorithm FCM and to use other methods, so that the results of clustering are more optimal.
本研究旨在展示使用FCM算法对Undiksha学生学费(UKT)进行聚类的结果。每个聚类的特征,测量水平,实现算法FCM在确定UKT中的精度。本研究中使用的学生学费数据包括SBMPTN 2017年的学生学费。学生的数据来自30名学生,有7个参数,分别是父母的职业、父母的收入、受抚养人的数量、资产、水费支付、电子电压、车辆品种。学生的学费数据分为四组,分别是ukt1、ukt2、ukt3和ukt4。在Matlab软件2017a支持下,采用FCM方法对学生学费进行分组,所得数据显示,ukt1分为89人,ukt2分为91人,ukt3分为79人,ukt4分为46人。根据最后一次迭代的中心向量(v)的结果,从每个参数中收集每个学生学费的数据特征。结果表明,FCM法在0.78范围内具有较高的准确度。因子分析结果显示,从7个参数来看,3个因素决定了学生的学费,分别是收入因素、开除因素和负荷因素。另一方面,未来的研究可以将FCM算法中的3个因素分组为计算变量,并使用其他方法,使聚类结果更优。
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引用次数: 3
An Interactive Augmented Reality Architectural Design Model : A Prototype for Digital Heritage Preservation 交互式增强现实建筑设计模型:数字遗产保护的原型
Pub Date : 2019-10-01 DOI: 10.1109/ICACSIS47736.2019.8979767
A. Indraprastha
We present study on the integration of augmented reality using Microsoft Hololens and architectural design documentation for cultural heritage application by practical evaluation method. Our goal is to understand the potential of AR implementation in architectural narration and documentation. Herein, we outlined our works: 1) Visualization of architectural forms; 2) Data visualization embedded in augmented environment; 3) Basic user interaction mechanism. Our focus of the study is on the methodology and workflows involved in the AR platform. The case study is traditional Balinese architectures that constitute issues of materiality, tectonics, aesthetics and embodied local and specific information, hence the cultural heritage. Our study found that AR and Hololens provide a promising tool for 3D visualization and experiences particularly in cultural heritage application where computer-generated objects are augmented into real and physical objects. Despite latency, limited visual field and interaction methods that are still in development, implementation of AR in the architectural field bring understanding architecture as a medium and interface where space, form, and information are combined
通过实际评估方法,对微软Hololens增强现实技术与建筑设计文献的融合进行了研究。我们的目标是了解AR实现在架构叙述和文档方面的潜力。在此,我们概述了我们的工作:1)建筑形式的可视化;2)增强环境中嵌入的数据可视化;3)基本的用户交互机制。我们研究的重点是AR平台所涉及的方法和工作流程。本案例研究的是巴厘岛传统建筑,这些建筑构成了材料、构造、美学等问题,并体现了当地和特定的信息,因此是文化遗产。我们的研究发现,AR和Hololens为3D可视化和体验提供了一个很有前途的工具,特别是在文化遗产应用中,计算机生成的物体被增强为真实的和物理的物体。尽管延迟,有限的视野和交互方法仍在开发中,但AR在建筑领域的实施使人们认识到建筑是空间,形式和信息结合的媒介和界面
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引用次数: 3
Adult Content Classification on Indonesian Tweets using LSTM Neural Network 基于LSTM神经网络的印尼文推文成人内容分类
Pub Date : 2019-10-01 DOI: 10.1109/ICACSIS47736.2019.8979982
A. Hidayatullah, Anisa Miladya Hakim, Abdullah Aziz Sembada
In the last decade, social media networking sites have become an inseparable part of people’s life. However, not all of content in social media contain beneficial and necessary information. This can be seen from the existing of negative and harmful content in social media, such as adult or pornographic content. Therefore, this study aims to build a model for adult content classification by using Long Short Term Memory (LSTM) Neural Network to classify adult content and non-adult content. We also compared our LSTM methods with Multinomial Naive Bayes, Logistic Regression, and Support Vector Classification. According to our experiments, the best model was obtained from the LSTM model with two LSTM layers and dropout reached the accuracy of 98,39% and the loss value of 5,08&.
在过去的十年里,社交媒体网站已经成为人们生活中不可分割的一部分。然而,并非社交媒体上的所有内容都包含有益和必要的信息。这可以从社交媒体中存在的负面有害内容中看出,例如成人或色情内容。因此,本研究旨在构建成人内容分类模型,利用LSTM神经网络对成人内容和非成人内容进行分类。我们还将LSTM方法与多项朴素贝叶斯、逻辑回归和支持向量分类进行了比较。根据我们的实验,两层LSTM的LSTM模型得到了最好的模型,dropout的准确率达到了98.39%,损失值为5.08 &。
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引用次数: 2
Role of IT in IT Governance Practices Maturity Perspective IT在IT治理实践成熟度视角中的角色
Pub Date : 2019-10-01 DOI: 10.1109/ICACSIS47736.2019.8979844
Dimas Agung Saputra, I. Alif, R. Wijaya, Y. G. Sucahyo, M. K. Hammi
In the organization, IT should be sustained and extended from the organization’s strategy and objectives of business. Good IT governance can increase the effectiveness of IT utilization by aligning business and IT strategy. Organization also need to know what the role of IT to give understanding about the IT utilization consequences for business impact. The purpose of this study is to analyse the role of IT in IT governance practices maturity perspective which implemented in the organization. This study compose relevant maturity model based on theory of IT governance practices that have relation to two key dimensions of IT Strategic Impact Grid. There are five case studies to verify the proposed maturity model, a case from Indonesian Telecommunication Company and four cases from the study of related IT governance practices. From the case studies result, IT governance practices can provide an understanding related to the utilization of IT roles in an organization. The maturity of business/IT alignment is consistent with the two key dimensions of IT Strategic Grid maturity but it possible to get the lower or higher maturity measurement result comparison with business/IT alignment maturity because of the different weight effectiveness. Details on IT governance practices could help the Board or CIO to take further action to achieve target maturity that accordance with the desired role of IT in the organization
在组织中,IT应该从组织的战略和业务目标中得到持续和扩展。良好的IT治理可以通过调整业务和IT策略来提高IT利用的有效性。组织还需要知道IT的角色,以便了解IT利用对业务影响的后果。本研究的目的是分析IT在组织中实现的IT治理实践成熟度视角中的作用。本研究以IT治理实践理论为基础,构建了与IT战略影响网格两个关键维度相关的成熟度模型。有五个案例研究来验证所建议的成熟度模型,一个来自印度尼西亚电信公司的案例和四个来自相关IT治理实践研究的案例。从案例研究的结果来看,IT治理实践可以提供与组织中IT角色的利用相关的理解。业务/IT对齐成熟度与IT战略网格成熟度的两个关键维度是一致的,但由于权重有效性的不同,与业务/IT对齐成熟度比较,可能得到较低或较高的成熟度度量结果。关于IT治理实践的详细信息可以帮助董事会或CIO采取进一步的行动,以实现与组织中期望的IT角色相一致的目标成熟度
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引用次数: 4
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2019 International Conference on Advanced Computer Science and information Systems (ICACSIS)
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