Journal of oral biology and craniofacial research最新文献

{"title":"Evaluation of buccolingual and linguobuccal implants in the atrophic posterior mandible: A finite element analysis study","authors":"Moyfat Karimov ,&nbsp;Goksel Timarcioglu ,&nbsp;Celal Candirli","doi":"10.1016/j.jobcr.2024.10.009","DOIUrl":"10.1016/j.jobcr.2024.10.009","url":null,"abstract":"<div><h3>Aim</h3><div>This study aims to evaluate the stress distribution on buccolingual and linguobuccal tilted implants in the atrophic posterior mandible using finite element analysis.</div></div><div><h3>Material and methods</h3><div>Twelve digital models of implants with varying lengths (8.5 mm, 10 mm, 11.5 mm) and angles (20°, 25°) were created. These implants were analyzed under 150 N vertical and oblique forces to assess stress distribution on both implants and surrounding bone.</div></div><div><h3>Results</h3><div>Linguobuccal implants generally exhibited lower maximum principal stress in cortical bone, while buccolingual implants showed lower minimum principal stress. Longer implants reduced stress under oblique loading.</div></div><div><h3>Conclusion</h3><div>Tilted implants, particularly using the linguobuccal method, are effective for stress distribution in the atrophic posterior mandible. Further research should explore varying implant diameters and multiple placements for optimization.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"14 6","pages":"Pages 793-801"},"PeriodicalIF":0.0,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142528185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of efficacy of digital or virtual bite registration over conventional techniques- A systematic review","authors":"Priyanjali Paul,&nbsp;Tridib Nath Banerjee,&nbsp;Saurav Banerjee,&nbsp;Anasua Debnath","doi":"10.1016/j.jobcr.2024.10.007","DOIUrl":"10.1016/j.jobcr.2024.10.007","url":null,"abstract":"<div><h3>Background</h3><div>Bite registration procedures have been transformed by the digital revolution in dentistry, thus it is now necessary to compare the accuracy of digital or virtual techniques to conventional ones.</div></div><div><h3>Aim</h3><div>To assess the accuracy of digital or virtual bite registration systems in comparison to conventional methods to clarify any potential advantages or disadvantages.</div></div><div><h3>Methodology</h3><div>A thorough search in numerous databases, including PubMed, Embase, the Cochrane Library, Scopus, and Web of Science, was carried out in accordance with PRISMA criteria. The review focused on the accuracy of digital or virtual bite registration and covered a variety of study formats, including randomized controlled trials, clinical studies, and in-vitro investigations. For each of the included 7 studies, a thorough assessment of bias was conducted using the Newcastle-Ottawa Scale and the Cochrane Risk of Bias tool. As there would be expected variability in study designs, data synthesis required both a narrative explanation of the results and a qualitative synthesis.</div></div><div><h3>Results</h3><div>This systematic review compared 7 studies on traditional bite registration methods versus digital/virtual techniques. Digital techniques highlighted improved efficiency and innovation with increased speed, accuracy, and integration advantages. Evaluations performed with the Newcastle-Ottawa Scale and ROBINS-I tool showed little bias in cross-sectional studies. Nevertheless, in vitro studies have identified biases in participant selection and result reporting, indicating a need for better study rigor and reporting standards. A study received a noteworthy 8 out of 9 score on the Newcastle-Ottawa Scale, indicating strong methodology with careful sample selection, solid comparability, and comprehensive outcome evaluation, enhancing its credibility in assessing bite registration techniques.</div></div><div><h3>Conclusion</h3><div>The benefits of digital/virtual bite registration methods over traditional ones are demonstrated in this systematic review, which also shows how these methods improve speed, accuracy, and integration. Although some studies have shown biases, overall results support the validity and efficiency of digital techniques in improving dental practice.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"14 6","pages":"Pages 785-792"},"PeriodicalIF":0.0,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142528186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mari's novel T shaped incision in frenotomy technique with bilateral pedicle flap- an aesthetic approach","authors":"K. Rudhra ,&nbsp;Ranjith Mari ,&nbsp;Anitha Balaji ,&nbsp;Mohan Valiathan","doi":"10.1016/j.jobcr.2024.09.008","DOIUrl":"10.1016/j.jobcr.2024.09.008","url":null,"abstract":"<div><h3>Background</h3><div>Aberrant frenum attachments often lead to mucogingival deformities, culminating in both functional impairments and aesthetic concerns. Traditional frenectomy procedures are associated with extensive incisions and resultant wound defects. To address these challenges, a novel T-shaped incision technique has been developed. This method enhances accessibility for removing vestibular and frenal attachments while creating a tripod layer of flaps, thereby promoting primary closure and improved blood supply for healing by primary intention.</div></div><div><h3>Case management</h3><div>This innovative technique is particularly suited for managing frenum variations such as bifid frenum, persistent tectolabial frenum, double frenum, and wider frenum. The procedure involves crafting two horizontal and two converging parallel incisions that form a “T\" shape, facilitating effective fiber detachment. Bilateral pedicle flaps are then employed for primary closure, which concurrently enlarges the zone of attached gingiva.</div></div><div><h3>Conclusion</h3><div>The T-shaped incision approach presents an advanced method for treating abnormal frenum attachments, ensuring efficient fiber separation and fostering healing by primary intention.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"14 6","pages":"Pages 782-784"},"PeriodicalIF":0.0,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142528184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unravelling the unique case of congenital infiltrating lipomatosis of face with its rare associations—A case report","authors":"Ramandeep Singh ,&nbsp;Aakash Gupta ,&nbsp;Gaurav Shanker Pradhan ,&nbsp;Arshit Kataria","doi":"10.1016/j.jobcr.2024.10.006","DOIUrl":"10.1016/j.jobcr.2024.10.006","url":null,"abstract":"<div><div>Congenital infiltrating lipomatosis of facial (CIL-F) is a rare tumour of adipose tissue resulting in a progressive craniofacial deformity with involvement of the underlying bones, muscles and joints. We report a very rare case of CIL-F with left sided temporomandibular joint ankylosis in a young patient who presented with facial swelling and reduced mouth opening. This case highlights the imaging features, differential diagnosis and brief management of CIL-F with special emphasis on CT and MRI findings. Also, some associations of CIL-F such as TMJ ankylosis and extraocular muscle hypertrophy has been described, which has been reported very rarely.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"14 6","pages":"Pages 767-772"},"PeriodicalIF":0.0,"publicationDate":"2024-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142528182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Myofibroblasts persist through immune privilege mechanisms to mediate oral submucous fibrosis: Uncovering the pathogenesis","authors":"Mohit Sharma ,&nbsp;Smitha Sammith Shetty ,&nbsp;Sonal Soi ,&nbsp;Raghu Radhakrishnan","doi":"10.1016/j.jobcr.2024.10.008","DOIUrl":"10.1016/j.jobcr.2024.10.008","url":null,"abstract":"<div><div>Immune privilege is the ability to tolerate foreign antigens without eliciting an inflammatory immune response. Several mechanisms explain a structure's immune privilege status, which is regulated by innate and adaptive immune responses. The role of myofibroblasts in perpetuating fibrosis by acquiring an immune privileged phenotype against the backdrop of oral submucous fibrosis (OSF) is evolving. Myofibroblasts persist through the Fas/FasL autocrine pathway and induce apoptosis in epithelial cells, explaining the juxtaposition of apoptotic cells in areas of fibrosis. However, increased matrix stiffness, in addition to activating TGF-β, reduces Fas surface expression in myofibroblasts, increasing their resistance to apoptosis. The reciprocal amplification loop between the immune checkpoint proteins programmed death-ligand 1 (PD-L1) and TGF-β involves the YAP-TAZ and SMAD2,3 pathways and dramatically enhances profibrotic signalling. Increased matrix stiffness also enhances cMYC expression, which subsequently amplifies PD-L1 levels on myofibroblasts. The increase in PD-L1 on the myofibroblast microengineers the phenotype of CD4⁺ T cells homing to fibrotic areas by acting on the programmed cell death protein 1 (PD-1) receptor on the T-cell surface, converting these cells from antifibrotic cells to profibrotic cells that produce IL-17A and TGF-β. This manuscript provides mechanistic insight into how myofibroblasts avoid apoptosis in OSFs by evading the immune system. Targeting an immune-privileged phenotype in myofibroblasts with FAS-FASL pathway-dependent characteristics is an ideal strategy for reversing OSF.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"14 6","pages":"Pages 773-781"},"PeriodicalIF":0.0,"publicationDate":"2024-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142528183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Three-dimensional finite element analysis of stress distribution on different complex macro designs in commercially available implants: An in-vitro study","authors":"Saranya V ,&nbsp;Mervin Harris ,&nbsp;Silpa Abraham ,&nbsp;Ramanarayanan Venkitachalam ,&nbsp;Shiv Shankar Nair ,&nbsp;Anil Mathew","doi":"10.1016/j.jobcr.2024.10.003","DOIUrl":"10.1016/j.jobcr.2024.10.003","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to investigate the effects of different commercially available complex implant macro designs on stress distributions using Finite element analysis. The experiment is done under varying simulated bone conditions to provide reference for clinical application.</div></div><div><h3>Materials and methods</h3><div>The study employed the Finite Element Analysis (FEA) method to compare four commercially available complex implant macro designs on a Computer-Aided Design (CAD) model of a maxillary bone segment. The three-dimensional geometrical model of the implants was reconstructed from computed tomography (CT)-slices in Digital Imaging and Communications in Medicine (DICOM) format and contact condition between the implant and the bone was considered as ‘Bonded’, implying perfect osseointegration. All materials used in the models were assumed to be isotropic, homogeneous, and linearly elastic. The Finite element simulations employed load of 400 N under both axial and non-axial conditions Stresses were analysed under different bone conditions.</div></div><div><h3>Results</h3><div>Average values of von Mises stresses were used for comparing stress levels between implant designs. There was a definite increase in the equivalent stress values from higher density(D1)to lower density (D4) bone conditions for all implants. The percentage of increase ranged from 23.63 to 49.39 on axial loading and 20.39 to 57.19 when subjected to non-axial loading. The equivalent stress values resulted from non-axial loading were 1.78–2.94 times higher than that of axial loading for all implants under all bone densities. Among the complex designs Equinox Myriad Plus implant exhibited the least stress under axial loading (12.749–19.046 MPa) and (37.462–49.217 MPa) for non-axial loading. The stress on the crestal module was higher (1.49–2.99 times) than the overall stress on the implant regardless of the loading direction or bone conditions.</div></div><div><h3>Conclusions</h3><div>Data from the present study shows Equinox Myriad Plus implant generating the least equivalent stress and this can be taken as indicator in the biomechanical performance of the design.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"14 6","pages":"Pages 761-766"},"PeriodicalIF":0.0,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142528187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of different agents on preload force of dental implants with bio high-performance poly-ether-ether-ketone abutments","authors":"Sabina Mary Paul,&nbsp;Kuttae Viswanathan Anitha,&nbsp;Muthukumar Balasubramaniam","doi":"10.1016/j.jobcr.2024.10.004","DOIUrl":"10.1016/j.jobcr.2024.10.004","url":null,"abstract":"<div><h3>Purpose</h3><div>This study evaluated the influence of different agents such as blood, artificial saliva, and normal saline on preload force of dental implants with bio-high-performance poly-ether-ether-ketone (Bio-HPP) abutments to determine its effect on screw loosening.</div></div><div><h3>Methods</h3><div>Forty (N = 40) Grade 5 titanium dental implant analog (GM Implant Analog; Neodent, Straumann) with Bio-HPP poly ether-ether ketone (PEEK) abutment and titanium screw was used in the study. The samples were embedded in acrylic split mold. In the control Group C, no agent was added. In the other three groups, blood (B), normal saline (N) and saliva (S) was added in the access cavity of the samples. A sequential torque of 15 Ncm, 20 Ncm, 25 Ncm, 30 Ncm up to 35 Ncm was applied with a digital torque meter (Eclatorq, model: SD-05bn, range:2.5–50 Ncm, torque accuracy: ± 2%cw). Samples were subjected to thermomechanical cyclic loading at 5–55⁰ Celsius for 1000 cycles (Chewing simulator, CS 4.4) to simulate six months of clinical service. Preload was measured as reverse torque value (RTV). Raw data in the form of mean ± standard deviation was documented and subjected to statistical analysis. A one-way ANOVA was performed to contrast the groups. Tukey HSD test was used to determine the multiple comparison assessment (<em>P</em> &lt; 0. 05).</div></div><div><h3>Results</h3><div>A mean reverse torque value of 35 Ncm ±0.00 was observed in both control and in groups exposed to normal saline (<em>P &gt;</em>.05). Measurements of 33.4 Ncm ±2.51 and 34.8 Ncm ±0.40 were found when exposed to blood and artificial saliva in order (<em>P</em> &lt; .05). When compared with control, exposure to blood showed significant variation in preload (<em>P</em> = .03).</div></div><div><h3>Conclusion</h3><div>A significant reduction in reverse torque force was observed when titanium implants and Bio-HPP abutments were exposed to blood, suggesting a potential risk of screw loosening (P &lt; .05). In contrast, minimal decrease and no significant change in preload were noted with exposure to saliva and normal saline (P &gt; .05).</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"14 6","pages":"Pages 756-760"},"PeriodicalIF":0.0,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142446644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship of tooth shade and skin tone and its influence on smile attractiveness in native South Indians: A web-based cross sectional survey","authors":"Hrudi Sundar Sahoo,&nbsp;Aishwarya Balasubramanian","doi":"10.1016/j.jobcr.2024.10.005","DOIUrl":"10.1016/j.jobcr.2024.10.005","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aimed to investigate the influence of tooth shade and skin tone on smile attractiveness among native South Indians. The primary research question was whether there is a significant relationship between these variables and perceived smile attractiveness.</div></div><div><h3>Materials and methods</h3><div>A web-based cross-sectional survey was conducted with approval from the Institutional Review Board of (Thai Moogambigai Dental College and Hospital, Chennai). Standardized smile photographs of two South Indian models (one male and one female) were digitally modified to display four different tooth shades and four different skin tones, resulting in 32 images. These images were incorporated into a Google Form along with a questionnaire and a Visual Analog Scale (VAS) for attractiveness rating. The survey was distributed to 1200 participants, including both dental professionals and the general population, with 1000 valid responses recorded. Statistical analysis was performed using IBM SPSS Statistics, employing parametric tests to evaluate the data.</div></div><div><h3>Results</h3><div>The study found that lighter tooth shades were consistently rated higher in attractiveness for both genders. Lighter tooth shades such as FS1T1 and FS2T1 scored means of 6.88 and 7.27 respectively for females, while darker shades like FS1T4 scored lower with a mean of 4.95. Similarly, males showed a preference for lighter tooth shades with MS1T1 and MS2T1 scoring means of 5.57 and 5.78 respectively compared to darker shades like MS1T4 with a mean of 3.63. Significant differences were noted across age groups and genders, with younger participants and females showing a stronger preference for lighter tooth shades.</div></div><div><h3>Conclusions</h3><div>The study concludes that both tooth shade and skin tone significantly influence smile attractiveness, with a clear preference for lighter tooth shades among the surveyed population. These findings suggest the importance of considering these factors in aesthetic dental treatments to enhance patient satisfaction and achieve optimal results.</div></div><div><h3>Clinical relevance</h3><div>The results underscore the necessity for dental practitioners to take into account both tooth shade and skin tone when planning aesthetic dental treatments. This approach will help in achieving a more harmonious and natural appearance, ultimately improving patient satisfaction with the treatment outcomes. Future research should continue to explore the cultural and individual factors that contribute to these preferences in dental aesthetics.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"14 6","pages":"Pages 746-750"},"PeriodicalIF":0.0,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142442170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparative evaluation of the antimicrobial efficacy of Chlorhexidine and Chlorine dioxide on self-ligating brackets contaminated with Streptococcus mutans biofilm- An In vitro study","authors":"Ashish Kumar Singh ,&nbsp;Yash Salkar ,&nbsp;Puneet Batra ,&nbsp;Garima Arora ,&nbsp;Shakila Mahesh","doi":"10.1016/j.jobcr.2024.10.001","DOIUrl":"10.1016/j.jobcr.2024.10.001","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate and compare antimicrobial efficacy of Chlorhexidine and Chlorine dioxide mouthwashes on <em>S</em>.<em>mutans</em> biofilm created on metal and ceramic self-ligating brackets.</div></div><div><h3>Materials and methods</h3><div>A total of 162 metal and ceramic self-ligating brackets (3M™ SmartClip™ &amp; Clarity SL™) were randomly divided into 3 groups and 2 subgroups. Standard procedures were followed to coat all brackets with <em>S</em>.<em>mutans</em> biofilm. The biofilms were cultivated which were then subjected to the effects of the mouthwashes. Quantitative assessment was carried out by comparing the number of viable colonies of <em>S</em>.<em>mutans.</em> A Mann-Whitney <em>U</em> test was used to compare the data between the experimental and control groups. (<em>p</em> &lt; 0.05).</div></div><div><h3>Result</h3><div>When compared to untreated controls the antimicrobial efficacy of Chlorhexidine Digluconate and Chlorine Dioxide mouthwashes was found to be statistically significant (<em>p</em> = 0.00). The comparison between Chlorhexidine digluconate and Chlorine dioxide mouthwashes was not statistically significant in Ceramic self-ligating group (<em>p</em> = 0.502) and statistically significant in Metal self-ligating group (<em>p</em> = 0.001)</div></div><div><h3>Conclusion</h3><div><em>S mutans</em> colonies on metal and ceramic self-ligating brackets can be reduced effectively by Chlorhexidine digluconate and Chlorine dioxide mouthwashes. Chlorhexidine digluconate more effective for metal bracket group. Both mouthwashes had comparable antimicrobial effectiveness, with the difference in the number of viable colonies following exposure for ceramic bracket groups.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"14 6","pages":"Pages 751-755"},"PeriodicalIF":0.0,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142442172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of ABO phenotype, rhesus factor, platelet count and hemoglobin level with oral hygiene status and severity of chronic periodontitis","authors":"Mohd Aamir Khan ,&nbsp;Nand Lal ,&nbsp;Tulika Chandra ,&nbsp;Wahid Ali ,&nbsp;Hira Ismail","doi":"10.1016/j.jobcr.2024.09.015","DOIUrl":"10.1016/j.jobcr.2024.09.015","url":null,"abstract":"<div><h3>Background</h3><div>The development of periodontal diseases has multifactorial causes including genetic factors. Limited investigations have been conducted to explore the association between ABO blood groups and the development and progression of periodontal diseases.</div></div><div><h3>Aim</h3><div>To evaluate and assess the association of ABO Phenotype and Rhesus factor with oral hygiene status, severity of chronic periodontitis and blood parameters like hemoglobin level and Platelet count in localized and generalized chronic periodontitis.</div></div><div><h3>Material and methods</h3><div>Study was carried out on 100 patients, out of which 80 patients of Generalized Chronic Periodontitis and 20 patients of Localized Chronic Periodontitis. Patients were categorized into Mild, Moderate and Severe Periodontitis.</div></div><div><h3>Result</h3><div>A highly significant association was found between severity of periodontitis and blood groups with blood group B and O were found to be at a greater risk to develop moderate to severe form of chronic periodontitis. Also subjects with blood group B and O showed worst oral hygiene among all the blood groups. Also patients suffering from chronic periodontitis showed a general trend towards lower limit of both hemoglobin level and platelet.</div></div><div><h3>Conclusion</h3><div>Genetic factors such as ABO blood group antigens may act as a risk influencer that plays a role in progression and severity of the chronic periodontitis, with blood group B and O being worst affected. Another observation was that a long standing case of chronic periodontitis can lead to anemia thus having systemic implications.</div></div>","PeriodicalId":16609,"journal":{"name":"Journal of oral biology and craniofacial research","volume":"14 6","pages":"Pages 730-734"},"PeriodicalIF":0.0,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142437857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}