Statement of problem: The staining and discoloration of computer-aided design and computer-aided manufacture (CAD-CAM) and heat-polymerized denture base resins caused by cleaners and liquids influence material selection and patient instructions; systematic reviews, however, are lacking.
Purpose: The purpose of this systematic review was to evaluate whether CAD-CAM denture base resins exhibit more staining and discoloration compared with heat-polymerized resins after immersion in liquids and cleaners.
Material and methods: This review followed the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. Searches were conducted in the PubMed, Scopus, Web of Science, Embase, Google Scholar databases, and from the reference lists of articles found. The articles were screened by title and abstract, followed by full-text evaluation. Studies assessing the color change of milled or printed resins compared with heat-polymerized resins after immersion in liquids or cleaners were included. The risk of bias was evaluated using the Joanna Briggs Institute tool for quasi-experimental studies.
Results: Of the 1183 articles identified, 15 were included in this review. Printed resins showed higher staining and discoloration after immersion in cleaners and liquids, followed by heat-polymerized and milled resins.
Conclusions: Printed CAD-CAM resins showed more staining and discoloration, and milled resins showed lower stainability after immersion in liquids and cleaners when compared with heat-polymerized resins.
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