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Exploratory development and clinical research of a mixed reality guided radiotherapy positioning system 混合现实引导放射治疗定位系统的探索性开发和临床研究
IF 1.7 4区 综合性期刊 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2024-09-12 DOI: 10.1016/j.jrras.2024.101095
Sai Zhang , Heng Zhang , Qixuan Li , Ziyi Wang , Nannan Cao , Jiawei Sun , Kai Xie , Liugang Gao , Xinye Ni
<div><h3>Purpose</h3><p>This study aims to develop an application software deployed on HoloLens2 for guiding patient radiotherapy setup and assessing its feasibility and accuracy in radiotherapy.</p></div><div><h3>Methods</h3><p>The developed system features an application software deployed on the HoloLens2 device, enabling automatic tracking and registration of a virtual cube to the location of a real calibration cube. This functionality is achieved through the utilization of the Vuforia SDK, which determines the location point linking the virtual and real spaces. The system then generates a reference hologram based on simulated positioning computed tomography (CT) data sets and anchors this reference hologram at the determined location point. In the process of treatment positioning, the real human body in the scene of HoloLens2 is matched with the surface of the reference hologram to complete the positioning. This paper explores the factors that affect the accuracy of the system, namely the viewing distance and Angle, to determine the optimal conditions for using the system. Then, based on the optimal conditions, the error between the cone beam computed tomography (CBCT) data of patients (head, neck and chest and abdomen) obtained by the system and conventional positioning were compared by T-test method to evaluate the performance of the system.</p></div><div><h3>Results</h3><p>The observation distance had a minor impact on the system's accuracy, as there was no significant difference between the average six-dimensional error and the gold standard (all P > 0.05). A significant impact on the positioning error of the system was observed when the observation angle and isocentric deviation were both set at 45° (the vertical error was notably different from the gold standard, P < 0.05). The observation angle (0°–30°) exhibited a slight influence on the accuracy of the system (all P > 0.05). Patients with head and neck cancer exhibited a significant difference in positioning error between this system and the conventional method in the vertical direction (1.0 ± 0.9 mm vs. 1.8 ± 0.8 mm, P < 0.05), while no statistical significance was noted in other directions. Patients with chest and abdominal cancer showed significant discrepancies in the transformation between the two systems in lateral direction (1.9 ± 1.0 mm vs. 2.5 ± 0.7 mm, P < 0.05), vertical direction (1.4 ± 1.2 mm vs. 2.2 ± 1.1 mm, P < 0.05), and longitudinal direction (2.0 ± 1.2 mm vs. 3.1 ± 1.4 mm, P < 0.05), with no statistical significance found in rotation.</p></div><div><h3>Conclusion</h3><p>In this study, a radiotherapy treatment positioning system utilizing mixed reality guidance is introduced. This system demonstrates the capability to notably decrease positioning errors in the transformation of patients with chest and abdominal cancer, as well as in the vertical direction for patients with head and neck cancer. Furthermore, it shows enhancements in the overall a
本研究旨在开发一款部署在 HoloLens2 上的应用软件,用于指导患者的放射治疗设置,并评估其在放射治疗中的可行性和准确性。方法所开发系统的特点是在 HoloLens2 设备上部署了一款应用软件,能够自动跟踪和注册虚拟立方体与真实校准立方体的位置。这一功能是通过使用 Vuforia SDK 实现的,Vuforia SDK 可以确定连接虚拟空间和真实空间的位置点。然后,系统根据模拟定位计算机断层扫描(CT)数据集生成参考全息图,并将该参考全息图锚定在确定的位置点上。在治疗定位过程中,HoloLens2 场景中的真实人体与参考全息图的表面进行匹配,从而完成定位。本文探讨了影响该系统精度的因素,即观察距离和角度,以确定使用该系统的最佳条件。然后,在最佳条件的基础上,用 T 检验法比较了系统获得的患者(头颈部和胸腹部)锥束计算机断层扫描(CBCT)数据与传统定位之间的误差,以评价系统的性能。结果观察距离对系统的准确性影响较小,因为平均六维误差与金标准之间没有显著差异(所有 P > 0.05)。当观测角和等心偏差都设定为 45°时,系统的定位误差受到了明显影响(垂直误差与金标准有明显差异,P <0.05)。观察角度(0°-30°)对系统的准确性有轻微影响(均为 P > 0.05)。头颈部癌症患者的定位误差在垂直方向上与传统方法有显著差异(1.0 ± 0.9 mm vs. 1.8 ± 0.8 mm,P < 0.05),而在其他方向上没有统计学意义。胸部和腹部癌症患者在横向(1.9 ± 1.0 mm vs. 2.5 ± 0.7 mm,P < 0.05)、纵向(1.4 ± 1.2 mm vs. 2.2 ± 1.1 mm,P < 0.05)和纵向方向(2.0 ± 1.2 mm vs. 3.1 ± 1.4 mm,P < 0.05),旋转方向无统计学意义。该系统能够显著减少胸部和腹部癌症患者转型时的定位误差,以及头颈部癌症患者垂直方向的定位误差。此外,该系统还提高了放疗程序的整体准确性。
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引用次数: 0
Binomial Poisson Ailamujia model with statistical properties and application 具有统计特性的二项式泊松艾拉穆贾模型及其应用
IF 1.7 4区 综合性期刊 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2024-09-12 DOI: 10.1016/j.jrras.2024.101096
Safar M. Alghamdi , Muhammad Ahsan-ul-Haq , Olayan Albalawi , Majdah Mohammed Badr , Eslam Hussam , H.E. Semary , M.A. Abdelkawy

In this study, an improved extension of the Poisson-Ailamujia distribution is introduced. The new distribution was derived using a binomial mixing approach, and the new model is named the “Binomial Poisson-Ailamujia (Bin-PA)” distribution. Some important statistical properties are derived, including mode, quantile function, moments and their associated measures, actuarial (risk) measures, and reliability features such as survival, hazard (failure) rate, and mean residual life function. The parameters of the proposed distribution are estimated using the maximum likelihood estimation method. A comprehensive simulation study is also carried out to access the behavior-derived maximum likelihood estimators. Furthermore, a new count-regression model was also introduced. Two datasets are utilized to demonstrate the applicability and usefulness of the new model. It is concluded that the Binomial Poisson-Ailamujia distribution is more flexible and efficiently analyzed both datasets as compared to competitive discrete distributions.

本研究介绍了泊松-艾拉穆贾分布的改进扩展。新分布是用二项混合方法推导出来的,新模型被命名为 "二项泊松-Ailamujia(Bin-PA)"分布。推导出了一些重要的统计特性,包括模式、量子函数、矩及其相关度量、精算(风险)度量,以及存活率、危险(故障)率和平均残余寿命函数等可靠性特征。采用最大似然估计法对拟议分布的参数进行了估计。还进行了全面的模拟研究,以获取行为衍生最大似然估计值。此外,还引入了一个新的计数回归模型。利用两个数据集证明了新模型的适用性和实用性。结论是,与竞争性离散分布相比,二项泊松-Ailamujia 分布更灵活、更有效地分析了这两个数据集。
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引用次数: 0
Radiation protection in dental imaging: Evaluating the impact of the SABA thyroid shield during panoramic and cone beam computed tomography 牙科成像中的辐射防护:评估 SABA 甲状腺防护罩在全景和锥形束计算机断层扫描中的影响
IF 1.7 4区 综合性期刊 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2024-09-12 DOI: 10.1016/j.jrras.2024.101102
Omemh Bawazeer , Hanan Almutairi , Khulood Almutiri , Alaa Fallatah , Mohamed Alasmary , Younis Bokhary , Mohamed Abuzaid , Abdulwali Ajlouni , Saeed Bawazir , Saeed Al-Qahtani , Mohammad Qutub , Emtenan Alotaibi , Merfat Algethami , Marwan Alhazmi

Background

Dental panoramic radiography (DPR) and cone beam computed tomography (CBCT) are an imaging modalities in dentistry. However, these procedures involve exposure to ionising radiation, raising concerns about radiation-induced thyroid damage. To mitigate these risks, thyroid shields have been introduced. This study aimed to evaluate the effectiveness of the SABA thyroid shield in reducing thyroid radiation exposure during DPR and CBCT scans.

Method

An experimental study to measure surface dose in the thyroid region during (DPR) and (CBCT) scans using an Anthropomorphic Phantom and a Solid-State Detector. The attenuation percentage was calculated between radiation surface doses with and without shielding. The significance of the Saba thyroid shield was calculated using a t-test.

Results

For DPR scans, the average surface doses in the thyroid reduced significantly from 301.1 μGy (at 85 kVp) and 170.3 μGy (at 60 kVp) to 64.43 μGy and 12.94 μGy, respectively, when the Saba thyroid shield was used. For CBCT scans, the average surface doses in the thyroid decreased significantly from 814.43 μGy (for 11 × 13 cm2 field size) and 32.40 μGy (for 5 × 5 cm2 field size) to 62.91 μGy and 12.07 μGy, respectively, with the application of the Saba thyroid shield. The maximum attenuation percentages in the thyroid for the DPR and CBCT scans were 92.40% and 92.27%, respectively. Statistically significant differences between the surface dose reduction with the Saba shield and without it was observed in both DPR scans (p < 0.0000) and CBCT scans (p < 0.0003).

Conclusion

The study demonstrates that Saba thyroid shields effectively reduce doses in the thyroid region during dental DPR and CBCT scans. The dose reduction depends on tube voltage for DPR scans, field size, and its position for CBCT scans. Findings highlight the importance of using Saba thyroid shields to minimise radiation exposure and protect the thyroid gland during dental scans.

背景牙科全景放射摄影(DPR)和锥形束计算机断层扫描(CBCT)是牙科的一种成像方式。然而,这些程序需要暴露于电离辐射中,引起了人们对辐射诱发甲状腺损伤的担忧。为了降低这些风险,人们引入了甲状腺防护罩。本研究旨在评估SABA甲状腺防护罩在DPR和CBCT扫描过程中减少甲状腺辐射暴露的有效性。方法一项实验研究,使用人体模型和固态探测器测量(DPR)和(CBCT)扫描过程中甲状腺区域的表面剂量。计算了有屏蔽和无屏蔽时辐射表面剂量的衰减百分比。结果对于 DPR 扫描,当使用 Saba 甲状腺屏蔽时,甲状腺的平均表面剂量分别从 301.1 μGy (85 kVp 时)和 170.3 μGy (60 kVp 时)显著降低到 64.43 μGy 和 12.94 μGy。在 CBCT 扫描中,使用 Saba 甲状腺防护罩后,甲状腺的平均表面剂量分别从 814.43 μGy(11 × 13 平方厘米的视野尺寸)和 32.40 μGy(5 × 5 平方厘米的视野尺寸)显著降至 62.91 μGy 和 12.07 μGy。在 DPR 和 CBCT 扫描中,甲状腺的最大衰减率分别为 92.40% 和 92.27%。在 DPR 扫描(p <0.0000)和 CBCT 扫描(p <0.0003)中,使用 Saba 防护罩和不使用 Saba 防护罩所减少的表面剂量之间存在明显的统计学差异。在 DPR 扫描中,剂量的减少取决于管电压;在 CBCT 扫描中,剂量的减少取决于磁场大小及其位置。研究结果凸显了在牙科扫描过程中使用 Saba 甲状腺防护罩最大限度地减少辐照和保护甲状腺的重要性。
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引用次数: 0
Revealing the surprising: Computed tomography-guided exploration of paranasal sinuses incidental findings 揭示惊人之处计算机断层扫描引导下的副鼻窦探查偶然发现
IF 1.7 4区 综合性期刊 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2024-09-11 DOI: 10.1016/j.jrras.2024.101101
Mogahid M.A. Zidan , Abrar Altayeb , Assala Altayeb , Ahmed Alhaj , Ahmed Khalid , Reem Haytham , Nihad Alwaseela , Amel Alsaied Hasan Abd Elraheim , Ala M.A. Elgyoum , Amel F.H. Alzain , Fatima Eltayb M. Ageed , Moram A. Fagiry , Ali Bahny Alhailiy , Hamid Osman , Bahaaedin A. Elkhader , Mohammed S. Alqahtani , Mustafa Mahmoud

Background

Incidental findings (IFs) are unintentional discoveries that are unrelated to the original imaging goal. Imaging exams of persons with suspected intracranial disorders may reveal IFs in the paranasal sinuses (PNS). The current investigation aims to determine the frequency and features of unexpected discoveries in the PNS in persons who have had brain computed tomography (CT) scans for suspected intracranial abnormalities.

Methods

Between December 2022 and February 2023, 100 patients who met the inclusion criteria for clinically suspected intracranial disorders had CT brain scans as part of this retrospective cross-sectional study. Two board-certified radiologists with at least three years of experience assessed the CT scans independently. The study investigated the incidence and proportion of paranasal sinuses incidental findings (PNS IFs) observed during brain CT scans to detect brain abnormalities.

Results

The study discovered that 27% of patients had IFs, with the retired population (aged 61 and up) having the highest prevalence, particularly among men. Acute sinusitis was the most commonly diagnosed incidental finding (IF), accounting for 15% of total cases. In addition, we found polyps, retention cysts, chronic sinusitis, mucoceles, and fungal infections. Left-sided maxillary sinus abnormalities outnumbered right-sided ones. Bilateral involvement was unusual.

Conclusion

These findings emphasize the importance of addressing IFs in the PNS when treating patients, as they may necessitate further inspection or intervention. These results have the potential to help establish strategies for treating patients with incidental paranasal sinus findings, ultimately improving patient care.

背景意外发现(IFs)是与最初的成像目标无关的无意发现。对疑似颅内疾病患者进行成像检查时,可能会在鼻旁窦(PNS)中发现意外发现。本次调查旨在确定因疑似颅内异常而接受脑部计算机断层扫描(CT)的患者在副鼻窦中意外发现的频率和特征。方法在 2022 年 12 月至 2023 年 2 月期间,100 名符合临床疑似颅内疾病纳入标准的患者接受了脑部 CT 扫描,作为本次回顾性横断面研究的一部分。两名具有至少三年经验的注册放射科医师对 CT 扫描结果进行了独立评估。研究调查了在脑部 CT 扫描中观察到的副鼻窦偶然发现(PNS IFs)的发生率和比例,以检测脑部异常。结果研究发现,27% 的患者有 IFs,其中退休人群(61 岁及以上)的发生率最高,尤其是男性。急性鼻窦炎是最常见的诊断性偶然发现(IF),占总病例的 15%。此外,我们还发现了息肉、潴留囊肿、慢性鼻窦炎、粘液囊肿和真菌感染。左侧上颌窦异常多于右侧。结论这些发现强调了在治疗患者时处理上颌窦IF的重要性,因为这些IF可能需要进一步检查或干预。这些结果有可能有助于为偶然发现副鼻窦的患者制定治疗策略,最终改善患者护理。
{"title":"Revealing the surprising: Computed tomography-guided exploration of paranasal sinuses incidental findings","authors":"Mogahid M.A. Zidan ,&nbsp;Abrar Altayeb ,&nbsp;Assala Altayeb ,&nbsp;Ahmed Alhaj ,&nbsp;Ahmed Khalid ,&nbsp;Reem Haytham ,&nbsp;Nihad Alwaseela ,&nbsp;Amel Alsaied Hasan Abd Elraheim ,&nbsp;Ala M.A. Elgyoum ,&nbsp;Amel F.H. Alzain ,&nbsp;Fatima Eltayb M. Ageed ,&nbsp;Moram A. Fagiry ,&nbsp;Ali Bahny Alhailiy ,&nbsp;Hamid Osman ,&nbsp;Bahaaedin A. Elkhader ,&nbsp;Mohammed S. Alqahtani ,&nbsp;Mustafa Mahmoud","doi":"10.1016/j.jrras.2024.101101","DOIUrl":"10.1016/j.jrras.2024.101101","url":null,"abstract":"<div><h3>Background</h3><p>Incidental findings (IFs) are unintentional discoveries that are unrelated to the original imaging goal. Imaging exams of persons with suspected intracranial disorders may reveal IFs in the paranasal sinuses (PNS). The current investigation aims to determine the frequency and features of unexpected discoveries in the PNS in persons who have had brain computed tomography (CT) scans for suspected intracranial abnormalities.</p></div><div><h3>Methods</h3><p>Between December 2022 and February 2023, 100 patients who met the inclusion criteria for clinically suspected intracranial disorders had CT brain scans as part of this retrospective cross-sectional study. Two board-certified radiologists with at least three years of experience assessed the CT scans independently. The study investigated the incidence and proportion of paranasal sinuses incidental findings (PNS IFs) observed during brain CT scans to detect brain abnormalities.</p></div><div><h3>Results</h3><p>The study discovered that 27% of patients had IFs, with the retired population (aged 61 and up) having the highest prevalence, particularly among men. Acute sinusitis was the most commonly diagnosed incidental finding (IF), accounting for 15% of total cases. In addition, we found polyps, retention cysts, chronic sinusitis, mucoceles, and fungal infections. Left-sided maxillary sinus abnormalities outnumbered right-sided ones. Bilateral involvement was unusual.</p></div><div><h3>Conclusion</h3><p>These findings emphasize the importance of addressing IFs in the PNS when treating patients, as they may necessitate further inspection or intervention. These results have the potential to help establish strategies for treating patients with incidental paranasal sinus findings, ultimately improving patient care.</p></div>","PeriodicalId":16920,"journal":{"name":"Journal of Radiation Research and Applied Sciences","volume":"17 4","pages":"Article 101101"},"PeriodicalIF":1.7,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1687850724002851/pdfft?md5=40f4a1e5e6e8beb990e392ae66a7da17&pid=1-s2.0-S1687850724002851-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142168012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analyzing Burr-X competing risk model using adaptive progressive Type-II censored binomial removal data with application to electrodes and electronics 利用自适应渐进式 II 类删减二叉删除数据分析 Burr-X 竞争风险模型,并将其应用于电极和电子产品
IF 1.7 4区 综合性期刊 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2024-09-10 DOI: 10.1016/j.jrras.2024.101107
Ohud A. Alqasem , Mazen Nassar , Maysaa Elmahi Abd Elwahab , Ahmed Elshahhat

The aim of this paper is to investigate the Burr-X competing risks model in the context of adaptive progressively Type-II censored samples. In this scenario, the removal pattern is assumed to be a random variable that follows the binomial distribution, which is a more realistic assumption compared to assuming a fixed removal pattern. In this study, we explore both classical and Bayesian estimation approaches to estimate the parameters of the Burr-X competing risks model, as well as the reliability parameter and the parameter of the binomial distribution. The interval ranges of different parameters are determined by utilizing the asymptotic normality of the maximum likelihood estimators. Furthermore, the Bayes credible intervals are calculated by sampling from the joint posterior distribution using the Markov Chain Monte Carlo procedure. To assess the efficiency of the acquired estimators, a comprehensive simulation study that considered various types of experimental designs is conducted. Finally, two applications are considered by analyzing data sets of electrodes and electronics.

本文旨在研究 Burr-X 竞争风险模型在自适应渐进式 II 型删减样本中的应用。在这种情况下,移除模式被假定为遵循二项分布的随机变量,与假定固定的移除模式相比,这是一种更现实的假定。在本研究中,我们探索了经典和贝叶斯估计方法来估计 Burr-X 竞争风险模型的参数,以及可靠性参数和二项分布参数。利用最大似然估计值的渐近正态性确定了不同参数的区间范围。此外,贝叶斯可信区间是通过使用马尔科夫链蒙特卡罗程序从联合后验分布中采样计算得出的。为了评估所获得的估计器的效率,进行了一项综合模拟研究,考虑了各种类型的实验设计。最后,通过分析电极和电子设备的数据集,考虑了两种应用。
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引用次数: 0
Analysis of ZnO-SAE50 nanolubricant performance under variable thermal conductivity and solar radiations: Model for bidirectional stretchable surface 不同导热系数和太阳辐射条件下的 ZnO-SAE50 纳米润滑剂性能分析双向可拉伸表面模型
IF 1.7 4区 综合性期刊 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2024-09-10 DOI: 10.1016/j.jrras.2024.101106
Sadia Karim , Adnan , Basharat Ullah , Yasir Khan , Ahmed A. Altohamy , Lioua Kolsi , Lotfi Ben Said , Wajdi Rajhi

Analysis of thermal transport in nanolubricants is an interesting and potential topic. Hence, the current research focuses on the study of ZnO-SAE50 by adding the major effects of variable thermal conductivity, combined convection, and thermal radiations. The physical set up is designed for 3D dimensional flow through a surface and then investigated the results via numerical scheme. From detailed analysis of the physical results, it is examined that ZnO concentration and suction effects cause reduction in the fluid movement while for stretching case these variations are quite rapid than shrinking case. Further, the combined convective effects greatly influenced the fluid motion over the surface. The velocity G(η) increases rapidly under increasing Grashof effects and maximum motion is observed for stretching case. The temperature of ZnO-SAE50 enhanced due to increasing thermal radiations and ZnO concentration. However, minimal changes are investigated under variable thermal conductivity number ϵ, shterching/shrinking λ and maximum drop in the temperature is examined due to stronger Grashof number effects.

分析纳米润滑剂中的热传输是一个有趣而有潜力的课题。因此,当前的研究重点是研究 ZnO-SAE50 的热传导性、联合对流和热辐射的主要影响。研究设计了流经表面的三维流动物理装置,然后通过数值方案对结果进行了研究。通过对物理结果的详细分析,可以发现氧化锌浓度和吸力效应会导致流体运动减弱,而在拉伸情况下,这些变化要比收缩情况下迅速。此外,综合对流效应极大地影响了流体在表面的运动。在格拉肖夫效应增加的情况下,速度 G′(η)迅速增加,在拉伸情况下观察到最大运动。ZnO-SAE50 的温度随着热辐射和 ZnO 浓度的增加而升高。然而,在热传导系数ϵ、拉伸/收缩λ可变的情况下,温度变化极小,而在格拉肖夫数效应增强的情况下,温度下降最大。
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引用次数: 0
Assessing parotid gland function through diffusion weighted MRI during and post-radiotherapy in head and neck cancer patients 通过弥散加权磁共振成像评估头颈部癌症患者放疗期间和放疗后的腮腺功能
IF 1.7 4区 综合性期刊 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2024-09-09 DOI: 10.1016/j.jrras.2024.101094
Ahmad Ameri , Shaghayegh Hassas Yeganeh , Saeed Nasiri , Zahra Azizmohammadi , Mojtaba Ansari , Ainaz Sourati , Manijeh Beigi

Objectives

The purpose of this study was to evaluate the usefulness of apparent diffusion coefficient (ADC) variation in irradiated parotid glands during and after 3D conformal radiotherapy (3DCRT).

Materials and methods

This study enrolled 15 head and neck cancer (HNC) patients who were treated with 3DCRT underwent diffusion weighted imaging (DWI) at rest and after gustatory stimulation in three time points as follows: before, during (one day after receiving the mean dose 26 Gy) and 6 months after the end of radiotherapy (RT). Salivary Ejection Fraction (SEF) data was also obtained from salivary gland scintigraphy (SGS) at the same three time points as MRI. Mean ADC at rest and after stimulation (ADCr, ADCs) and SEF were extracted from parotid region for three time points. Finally, SEF and changes of ADC over time at rest and after stimulation and in each time point were compared.

Results

Difference between mean ADCr before RT and during RT was not significant (p = 0.12). The ADCr values were significantly higher after RT than before RT (p = 0.003) and during RT (after dose 26 Gy) (p = 0.001). The difference between ADCr and ADCs in each time point showed that there is significant difference between ADCr and ADCs before RT (p = 0.005). Difference between these parameters after RT was also significant (p = 0.05). Non-significant difference (p = 0.21) between ADCr and ADCs during RT was observed. The result of SEF also was significantly lower after RT than during (p = 0.008) and before RT (p = 0.001).

Conclusion

Mean ADC values could be used as a surrogate marker to characterize the parotid function in different stages of RT.

本研究的目的是评估三维适形放疗(3DCRT)期间和之后辐照腮腺表观弥散系数(ADC)变化的有用性。材料和方法本研究纳入了 15 名接受 3DCRT 治疗的头颈部癌症(HNC)患者,他们分别在放疗(RT)前、放疗期间(接受平均剂量 26 Gy 后一天)和放疗(RT)结束后 6 个月的三个时间点接受了静息状态下和味觉刺激后的弥散加权成像(DWI)。唾液腺射血分数(SEF)数据也是在与核磁共振成像相同的三个时间点通过唾液腺闪烁成像(SGS)获得的。提取腮腺区域在三个时间点的静息时和刺激后的平均 ADC(ADCr、ADCs)和 SEF。最后,比较静息时和刺激后以及每个时间点的 SEF 和 ADC 随时间的变化。RT 后的 ADCr 值明显高于 RT 前(p = 0.003)和 RT 期间(剂量 26 Gy 后)(p = 0.001)。各时间点的 ADCr 和 ADCs 之间的差异表明,RT 前的 ADCr 和 ADCs 之间存在明显差异(p = 0.005)。RT 后这些参数之间的差异也很明显(p = 0.05)。在 RT 期间,ADCr 和 ADCs 之间的差异不明显(p = 0.21)。结论 ADC 平均值可作为替代标记物来描述 RT 不同阶段的腮腺功能。
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引用次数: 0
Preparation & characterization of polyvinyl alcohol/thymol blue composites gel and films for low radiation dosimetry 用于低辐射剂量测定的聚乙烯醇/百里酚蓝复合凝胶和薄膜的制备与表征
IF 1.7 4区 综合性期刊 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2024-09-09 DOI: 10.1016/j.jrras.2024.101103
Mohammed A. Ali Omer , Abdalla Abdelkarem Abdalla

Background

Exposure to low radiation has been indispensable due to it is necessity in radiography and it is induced potential effects in patients and radiology staff. Hence the measurement and detection became inevitable for radiation practitioners and the patients. The study aimed to present the synthesis of polyvinyl alcohol gel doped with Thymol Blue dye (PVA/TB) as gel and films for low radiation dosimetry.

Method

The polymer was prepared under controlled parameters (PVA 5%, temperature 80 °C, dopped with 0.01, 0.03, 0.05, 0.07, 0.09 mw of TB). The formed gel and films were irradiated with x-ray as: 0, 2, 4, 6, 8, 10 mGy.

Results

Gel and films showed color quenching from yellow to light yellow as the radiation dose increased, as well as gradual significant (R2 = 0.97) reduction in optical density for all concentration (0.01, 0.02–0.09 mw of TB). The UV-spectroscope for (PVA/TB0.01mw) gel showed absorbance peaks at λ = 435, 326 and 279 nm, that decreased significantly (R2 = 0.97) as the radiation dose increases. And XRD for (PVA/TB0.01 mw) reveals the crystallinity of PVA at 2 thetas = 19.5° which increased to 40.5% at 10 mGy. FTIR revealed the chemical bonds with relevant intensities (CH (725.1–781 & 3030 cm−1), C – C (883.2 & 1170.6 cm−1), C – O (1063- 1096 cm−1), CH2 (1357.6 cm−1 wagging, 2879.2 cm−1 alkyl stretch), C = C (1623.8–1651.5 cm−1), C = O (1681.6–1683.6 cm−1), C – OH (3288 cm−1)) that decreased as the radiation dose increased and new radiogenic bonds at vibrational bands 1063–1096 cm−1 referring to C – O – C of Polysaccharide's pyranose and at 2125.1 cm−1 for C ≡ C alkenyl).

Conclusion

Both forms of PVA/TB films and gel showed feasibility and applicability for radiation detection and measurement.

背景由于在放射摄影中必须暴露于低辐射,而低辐射又会对患者和放射工作人员产生潜在影响,因此暴露于低辐射是不可或缺的。因此,对于放射从业人员和患者来说,测量和检测是不可避免的。本研究的目的是合成掺杂百里酚蓝染料(PVA/TB)的聚乙烯醇凝胶,作为凝胶和薄膜用于低辐射剂量测定。用 X 射线照射形成的凝胶和薄膜:结果随着辐射剂量的增加,凝胶和薄膜的颜色从黄色淬变为浅黄色,并且在所有浓度(0.01、0.02-0.09 mw 的 TB)下,光密度逐渐显著降低(R2 = 0.97)。PVA/TB0.01mw)凝胶的紫外光谱显示在 λ = 435、326 和 279 nm 处有吸光峰,随着辐射剂量的增加,吸光峰显著降低(R2 = 0.97)。PVA/TB0.01 mw)的 XRD 显示,PVA 的结晶度为 2 thetas = 19.5°,在 10 mGy 时增加到 40.5%。傅立叶变换红外光谱显示了相关强度的化学键(CH (725.1-781 & 3030 cm-1)、C - C (883.2 & 1170.6 cm-1)、C - O (1063- 1096 cm-1)、CH2 (1357.6 cm-1 wagging, 2879.2 cm-1 alkyl stretch)、C = C (1623.8-1651.5 cm-1)、C = O (1681.6-1683. 6 cm-1)、C - OH (1357.6 cm-1 wagging, 2879.2 cm-1 alkyl stretch))。结论两种形式的 PVA/TB 薄膜和凝胶都显示了辐射检测和测量的可行性和适用性。
{"title":"Preparation & characterization of polyvinyl alcohol/thymol blue composites gel and films for low radiation dosimetry","authors":"Mohammed A. Ali Omer ,&nbsp;Abdalla Abdelkarem Abdalla","doi":"10.1016/j.jrras.2024.101103","DOIUrl":"10.1016/j.jrras.2024.101103","url":null,"abstract":"<div><h3>Background</h3><p>Exposure to low radiation has been indispensable due to it is necessity in radiography and it is induced potential effects in patients and radiology staff. Hence the measurement and detection became inevitable for radiation practitioners and the patients. The study aimed to present the synthesis of polyvinyl alcohol gel doped with Thymol Blue dye (PVA/TB) as gel and films for low radiation dosimetry.</p></div><div><h3>Method</h3><p>The polymer was prepared under controlled parameters (PVA 5%, temperature 80 °C, dopped with 0.01, 0.03, 0.05, 0.07, 0.09 mw of TB). The formed gel and films were irradiated with x-ray as: 0, 2, 4, 6, 8, 10 mGy.</p></div><div><h3>Results</h3><p>Gel and films showed color quenching from yellow to light yellow as the radiation dose increased, as well as gradual significant (R<sup>2</sup> = 0.97) reduction in optical density for all concentration (0.01, 0.02–0.09 mw of TB). The UV-spectroscope for (PVA/TB<sub>0.01mw</sub>) gel showed absorbance peaks at λ = 435, 326 and 279 nm, that decreased significantly (R<sup>2</sup> = 0.97) as the radiation dose increases. And XRD for (PVA/TB<sub>0.01 mw</sub>) reveals the crystallinity of PVA at 2 thetas = 19.5° which increased to 40.5% at 10 mGy. FTIR revealed the chemical bonds with relevant intensities (CH (725.1–781 &amp; 3030 cm<sup>−1</sup>), C – C (883.2 &amp; 1170.6 cm<sup>−1</sup>), C – O (1063- 1096 cm<sup>−1</sup>), CH<sub>2</sub> (1357.6 cm<sup>−1</sup> wagging, 2879.2 cm<sup>−1</sup> alkyl stretch), C = C (1623.8–1651.5 cm<sup>−1</sup>), C = O (1681.6–1683.6 cm<sup>−1</sup>), C – OH (3288 cm<sup>−1</sup>)) that decreased as the radiation dose increased and new radiogenic bonds at vibrational bands 1063–1096 cm<sup>−1</sup> referring to C – O – C of Polysaccharide's pyranose and at 2125.1 cm<sup>−1</sup> for C ≡ C alkenyl).</p></div><div><h3>Conclusion</h3><p>Both forms of PVA/TB films and gel showed feasibility and applicability for radiation detection and measurement.</p></div>","PeriodicalId":16920,"journal":{"name":"Journal of Radiation Research and Applied Sciences","volume":"17 4","pages":"Article 101103"},"PeriodicalIF":1.7,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1687850724002875/pdfft?md5=c10828d50046df6844a1ae1c95015a12&pid=1-s2.0-S1687850724002875-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142163390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Image fusion: A deep Y shaped–residual convolution auto-encoder with MS-SSIM loss function 图像融合:带有 MS-SSIM 损失函数的深度 Y 型残差卷积自动编码器
IF 1.7 4区 综合性期刊 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2024-09-06 DOI: 10.1016/j.jrras.2024.101089
M. Gayathri Devi , I.S. Akila

Image fusion and deep learning are actively investigating fields of research. Their application domains include machine vision, clinical imaging, remote sensing, and other areas, all of which are used to obtain comprehensive information about a specific image. Image fusion is a process that integrates multiple imaging modalities to create a single image, for the sake of providing comprehensive information. Extensive literature shows that various methodologies, requirements, and network types are utilized for diverse modality fusion. This paper addresses the previously described issue by utilizing a unique Y-shaped Residual Convolution Autoencoder Neural Network to combine images from various modalities using the same network specifications and thereby eliminating the need for manual fusion. The combined convolved features are recreated in the decoder part using a symmetric nested residual approach with the encoder. By employing MS-SSIM as the loss function, the network is capable of generating images that are perceptually and pixel-wise indistinguishable from the target images. The fusion results are compared with five other current approaches, and the Y-shaped convolutional autoencoder result demonstrates superior achievement in both quantitative and qualitative aspects.

图像融合和深度学习是正在积极探索的研究领域。它们的应用领域包括机器视觉、临床成像、遥感等,都是为了获取特定图像的综合信息。图像融合是一种将多种成像模式整合在一起生成单一图像的过程,目的是提供全面的信息。大量文献表明,不同的方法、要求和网络类型被用于不同的模态融合。本文利用独特的 Y 型残差卷积自动编码器神经网络,使用相同的网络规格将来自不同模态的图像进行融合,从而消除了手动融合的需要,解决了之前描述的问题。解码器部分采用对称嵌套残差法与编码器一起重新创建合并的卷积特征。通过使用 MS-SSIM 作为损失函数,该网络能够生成在感知和像素上与目标图像无差别的图像。融合结果与其他五种现有方法进行了比较,Y 型卷积自动编码器的结果在定量和定性方面都取得了优异的成绩。
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引用次数: 0
Towards precise chronic disease management: A combined approach with binary metaheuristics and ensemble deep learning 实现精准的慢性病管理:二元元启发式与集合深度学习相结合的方法
IF 1.7 4区 综合性期刊 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2024-09-04 DOI: 10.1016/j.jrras.2024.101092
Nuzaiha Mohamed , Reem Lafi Almutairi , Sayda Abdelrahim , Randa Alharbi , Fahad M. Alhomayani , Azhari A. Elhag

Chronic disease (CD) recognition involves identifying the existence or risk of CDs in individuals. CDs have chronic health illnesses categorized by slow progression and frequent reduction from intricate reasons. CDs comprise chronic respiratory diseases, heart disease, diabetes mellitus, and certain cancers. Earlier diagnosis is vital in handling CDs proficiently. Then, it permits lifestyle modifications, timely intervention, and medical services to avoid the progression of the disease and reduce its effect on their health. Recently, technical development, particularly in healthcare statistics and artificial intelligence (AI), has assisted in advancing sophisticated approaches and systems for CD recognition. These methodologies usually employ deep learning (DL) and machine learning (ML) models for investigating enormous databases, identifying patterns, and making predictions that rely on distinct health-related parameters. This study presents an accurate chronic disease detection and classification model using binary meta-heuristics with an ensemble deep learning (ACDDC-BMEDL) approach. The ACDDC-BMEDL methodology focuses on the procedure of average ensemble classifier with meta-heuristic-based feature selection (FS) and hyperparameter tuning processes. The ACDDC-BMEDL methodology uses a binary arithmetic optimization algorithm (BAOA) to choose better feature subsets. Additionally, the ACDDC-BMEDL methodology uses an average ensemble technique encompassing recurrent neural network (RNN), gated recurrent unit (GRU), and extreme learning machine (ELM) for classification procedure. The marine predator's algorithm (MPA) is employed for the hyperparameter tuning process. The experimental value of the ACDDC-BMEDL methodology was examined on 2 CD datasets. The performance validation of the ACDDC-BMEDL methodology portrays a superior value of 98.70% and 94.51% with recent methods concerning several metrics under Diabetes and HD datasets.

慢性疾病(CD)识别包括识别个人是否患有慢性疾病或患有慢性疾病的风险。慢性疾病是一种慢性健康疾病,其特点是病情发展缓慢,并经常因复杂的原因而减轻。慢性疾病包括慢性呼吸系统疾病、心脏病、糖尿病和某些癌症。早期诊断对于有效处理 CD 至关重要。然后,可以通过调整生活方式、及时干预和医疗服务来避免疾病恶化,减少对健康的影响。近来,技术的发展,尤其是医疗统计和人工智能(AI)方面的发展,有助于推进CD识别的复杂方法和系统。这些方法通常采用深度学习(DL)和机器学习(ML)模型来调查庞大的数据库、识别模式并根据不同的健康相关参数进行预测。本研究提出了一种使用二元元启发式与集合深度学习(ACDDC-BMEDL)方法的精确慢性疾病检测和分类模型。ACDDC-BMEDL 方法侧重于平均集合分类器的程序,以及基于元启发式的特征选择(FS)和超参数调整过程。ACDDC-BMEDL 方法使用二进制算术优化算法(BAOA)来选择更好的特征子集。此外,ACDDC-BMEDL 方法在分类过程中使用了平均集合技术,包括循环神经网络(RNN)、门控循环单元(GRU)和极端学习机(ELM)。超参数调整过程采用了海洋捕食者算法(MPA)。在 2 个 CD 数据集上检验了 ACDDC-BMEDL 方法的实验价值。ACDDC-BMEDL 方法的性能验证结果表明,在糖尿病和 HD 数据集的多个指标上,ACDDC-BMEDL 方法分别比最近的方法高出 98.70% 和 94.51%。
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引用次数: 0
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Journal of Radiation Research and Applied Sciences
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