Pub Date : 2024-11-05DOI: 10.1016/j.supflu.2024.106452
Albert Rosado , Luis García-Fernández , María Rosa Aguilar , Rosa Ana Ramírez , Ana M. López-Periago , José A. Ayllón , Concepción Domingo
Despite the impressive characteristics of biological metal organic frameworks (bioMOFs) for their use as drug delivery systems (DDs), there are still some parameters related to their structural stability and processing routes that have decelerated their realistic application in this field. Both drawbacks are unraveled in this work for the microporous bioMOF CaSyr-1 by using supercritical CO2 (scCO2) to load the bioMOF with the anti-tubercular isoniazid (INH) drug, and functionalize its external surface with a hydrophobic protective layer of stearate (S). The hydrophobicized CaSyr-1(INH)/S vehicle is further coated with a neutral surfactant (PS60) to enhance the wettability of the system. In vitro tests, related to drug carrier biocompatibility and drug release in body simulated fluids, are performed to demonstrate potential prospective of the designed DDs in pharmacy. The synthetized product displayed total biocompatibility even at high concentrations, and the particle size and dissolution rate showed to be adequate for pulmonary administration.
{"title":"Supercritical CO2 assisted bioMOF drug encapsulation and functionalization for delivery with a synergetic therapeutic value","authors":"Albert Rosado , Luis García-Fernández , María Rosa Aguilar , Rosa Ana Ramírez , Ana M. López-Periago , José A. Ayllón , Concepción Domingo","doi":"10.1016/j.supflu.2024.106452","DOIUrl":"10.1016/j.supflu.2024.106452","url":null,"abstract":"<div><div>Despite the impressive characteristics of biological metal organic frameworks (bioMOFs) for their use as drug delivery systems (DDs), there are still some parameters related to their structural stability and processing routes that have decelerated their realistic application in this field. Both drawbacks are unraveled in this work for the microporous bioMOF CaSyr-1 by using supercritical CO<sub>2</sub> (scCO<sub>2</sub>) to load the bioMOF with the anti-tubercular isoniazid (INH) drug, and functionalize its external surface with a hydrophobic protective layer of stearate (S). The hydrophobicized CaSyr-1(INH)/S vehicle is further coated with a neutral surfactant (PS60) to enhance the wettability of the system. <em>In vitro</em> tests, related to drug carrier biocompatibility and drug release in body simulated fluids, are performed to demonstrate potential prospective of the designed DDs in pharmacy. The synthetized product displayed total biocompatibility even at high concentrations, and the particle size and dissolution rate showed to be adequate for pulmonary administration.</div></div>","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"216 ","pages":"Article 106452"},"PeriodicalIF":3.4,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142660511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This research investigates the extraction of compounds from Nepeta crispa (N. crispa), utilizing supercritical carbon dioxide green solvent, for the first time. Using RSM, the study examines the impact of pressure (15–25 MPa), temperature (313–333 K), and co-solvent (0.5–3.5%) on the extraction yield. The antioxidant activity of the essential oil is assessed through Ferric Reducing Antioxidant Power (FRAP) assay, while its antibacterial properties are evaluated against four bacterial strains. The SCFE method achieved a maximum yield of 1.812 % at optimum conditions (P= 25 MPa, T= 313 K and co-solvent= 3.5%). GC-Mass analysis revealed that the primary constituents of N. crispa essential oil which are 1,8-cineol and 4aα,7α,7aα-nepetalactone in both extraction methods. The antioxidant and antibacterial results of N. crispa showed the superiority of SC-CO2 over hydrodistillation method. These observed antioxidant and antibacterial attributes highlight the plant’s potential suitability for applications within the food and pharmaceutical industries.
{"title":"Supercritical CO2 green solvent extraction of Nepeta crispa: Evaluation of process optimization, chemical analysis, and biological activity","authors":"Saeid Matinfard , Hamid Tavakolipour , Gholamhossein Sodeifian , Seyed Ali Sajadian , Ramezan Kalvandi","doi":"10.1016/j.supflu.2024.106451","DOIUrl":"10.1016/j.supflu.2024.106451","url":null,"abstract":"<div><div>This research investigates the extraction of compounds from <em>Nepeta crispa</em> (<em>N. crispa</em>), utilizing supercritical carbon dioxide green solvent, for the first time. Using RSM, the study examines the impact of pressure (15–25 MPa), temperature (313–333 K), and co-solvent (0.5–3.5%) on the extraction yield. The antioxidant activity of the essential oil is assessed through Ferric Reducing Antioxidant Power (FRAP) assay, while its antibacterial properties are evaluated against four bacterial strains. The SCFE method achieved a maximum yield of 1.812 % at optimum conditions (P= 25 MPa, T= 313 K and co-solvent= 3.5%). GC-Mass analysis revealed that the primary constituents of <em>N. crispa</em> essential oil which are 1,8-cineol and 4aα,7α,7aα-nepetalactone in both extraction methods. The antioxidant and antibacterial results of <em>N. crispa</em> showed the superiority of SC-CO<sub>2</sub> over hydrodistillation method. These observed antioxidant and antibacterial attributes highlight the plant’s potential suitability for applications within the food and pharmaceutical industries.</div></div>","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"216 ","pages":"Article 106451"},"PeriodicalIF":3.4,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142660691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-31DOI: 10.1016/j.supflu.2024.106450
Xingyan Bian , Xuan Wang , Xuanang Zhang , Rui Wang , Jingyu Wang , Hua Tian , Gequn Shu
The transcritical CO2 (T-CO2) power cycle is regarded as one of the most promising alternatives to the steam power cycle in nuclear power plants. However, these plants often operate with transient cold source conditions, leading to deviations from the optimal design point and performance degradation. Therefore, this study examines a double recompression T-CO2 power cycle to optimize the design point pump inlet temperature and investigate part-load performance under cold source fluctuations. Results indicate that the lowest design point pump inlet temperature is optimal for low temperature cold sources and high load conditions to maximize thermal efficiency. When the system operates at 80 % load with a cold source temperature of 5 °C, the thermal efficiencies at the design point pump inlet temperature of 15 °C and 25 °C are 58 % and 56.93 %, respectively. In contrast, a moderate design point pump inlet temperature is better suited for accommodating wide fluctuations in operating conditions. A lower cold source temperature helps mitigate the reduction in thermal efficiency caused by load decreases. Furthermore, reducing the split ratio of low-temperature compressor can enhance thermal efficiency as the cold source temperature increases. These findings provide an effective approach to minimizing performance degradation in the T-CO2 power cycle under off-design conditions.
{"title":"Impact of cold source temperature on transcritical CO2 power cycle: Design point optimization and off-design performance analysis","authors":"Xingyan Bian , Xuan Wang , Xuanang Zhang , Rui Wang , Jingyu Wang , Hua Tian , Gequn Shu","doi":"10.1016/j.supflu.2024.106450","DOIUrl":"10.1016/j.supflu.2024.106450","url":null,"abstract":"<div><div>The transcritical CO<sub>2</sub> (T-CO<sub>2</sub>) power cycle is regarded as one of the most promising alternatives to the steam power cycle in nuclear power plants. However, these plants often operate with transient cold source conditions, leading to deviations from the optimal design point and performance degradation. Therefore, this study examines a double recompression T-CO<sub>2</sub> power cycle to optimize the design point pump inlet temperature and investigate part-load performance under cold source fluctuations. Results indicate that the lowest design point pump inlet temperature is optimal for low temperature cold sources and high load conditions to maximize thermal efficiency. When the system operates at 80 % load with a cold source temperature of 5 °C, the thermal efficiencies at the design point pump inlet temperature of 15 °C and 25 °C are 58 % and 56.93 %, respectively. In contrast, a moderate design point pump inlet temperature is better suited for accommodating wide fluctuations in operating conditions. A lower cold source temperature helps mitigate the reduction in thermal efficiency caused by load decreases. Furthermore, reducing the split ratio of low-temperature compressor can enhance thermal efficiency as the cold source temperature increases. These findings provide an effective approach to minimizing performance degradation in the T-CO<sub>2</sub> power cycle under off-design conditions.</div></div>","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"218 ","pages":"Article 106450"},"PeriodicalIF":3.4,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142789994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
High-pressure gas might affect the molecular chain movement, chain interaction, and crosslinking behavior of MVQ during the saturation process. In this paper, by comparing crosslinking exothermic behaviors of MVQ in air, CO2, and N2, it is found that the supercritical CO2 (scCO2) can promote crosslinking reaction of MVQ through enhancing the swelling and molecular chain's mobility. The result of rheological property shows the competitive relationship between crosslinking and plasticizing effects of MVQ in CO2. MVQ foams with different cellular structures and porosity are designed by balancing the crosslinking density and plasticization effect. MVQ foams prepared in this study have excellent compressive mechanical properties, and compressive stress can reach up to 1839 kPa at 40 % strain. This paper offers a reference for preparing thermosetting polymer foams in the aspect of crosslinking reaction and cellular structure regulation.
{"title":"Study on the crosslinking reaction and foaming behavior of silicone rubber in high-pressure fluids","authors":"Bo Wang, Wanyu Tang, Zuoze Fan, Ruyun Xu, Guangxian Li, Xia Liao","doi":"10.1016/j.supflu.2024.106449","DOIUrl":"10.1016/j.supflu.2024.106449","url":null,"abstract":"<div><div>High-pressure gas might affect the molecular chain movement, chain interaction, and crosslinking behavior of MVQ during the saturation process. In this paper, by comparing crosslinking exothermic behaviors of MVQ in air, CO<sub>2</sub>, and N<sub>2</sub>, it is found that the supercritical CO<sub>2</sub> (scCO<sub>2</sub>) can promote crosslinking reaction of MVQ through enhancing the swelling and molecular chain's mobility. The result of rheological property shows the competitive relationship between crosslinking and plasticizing effects of MVQ in CO<sub>2</sub>. MVQ foams with different cellular structures and porosity are designed by balancing the crosslinking density and plasticization effect. MVQ foams prepared in this study have excellent compressive mechanical properties, and compressive stress can reach up to 1839 kPa at 40 % strain. This paper offers a reference for preparing thermosetting polymer foams in the aspect of crosslinking reaction and cellular structure regulation.</div></div>","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"216 ","pages":"Article 106449"},"PeriodicalIF":3.4,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142578818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-29DOI: 10.1016/j.supflu.2024.106448
Crisleine P. Draszewski, Bruna C. Witter, Pedro A. Assini, Flávio D. Mayer, Ederson R. Abaide, Fernanda de Castilhos
Steam explosion (SE) pretreatment and sequentially subcritical water hydrolysis (SWH) was studied. Industrially, there is an advantage in using this process strategy, since it uses the same equipment and instrumentation, without the need to transport the raw material in separate stages. The influence of severity factors (SF) (2.75, 3.05, and 3.35) and solvent used (distilled water and 0.5 % w/w of H2SO4) were evaluated in the SE efficiency. SWH was perform in integrated processing using the best pre-treatment conditions. The influence of temperature (230 and 260 °C) and the solvent/feed ratio (40 and 80) were considered. The integrated system resulted in a FS yield of 19.19 ± 0.49 g/ 100 g SH, for a condition Integrated 230 °C, S/F-40, a FS yield 3.3 times greater than that obtained in the same condition with untreated soybean hulls, demonstrating the advantage of perform the process under this operating strategy (SE + SWH)
{"title":"Subcritical water hydrolysis of soybean hulls pretreated by steam explosion: High pressure integrated process strategy","authors":"Crisleine P. Draszewski, Bruna C. Witter, Pedro A. Assini, Flávio D. Mayer, Ederson R. Abaide, Fernanda de Castilhos","doi":"10.1016/j.supflu.2024.106448","DOIUrl":"10.1016/j.supflu.2024.106448","url":null,"abstract":"<div><div>Steam explosion (SE) pretreatment and sequentially subcritical water hydrolysis (SWH) was studied. Industrially, there is an advantage in using this process strategy, since it uses the same equipment and instrumentation, without the need to transport the raw material in separate stages. The influence of severity factors (SF) (2.75, 3.05, and 3.35) and solvent used (distilled water and 0.5 % w/w of H<sub>2</sub>SO<sub>4</sub>) were evaluated in the SE efficiency. SWH was perform in integrated processing using the best pre-treatment conditions. The influence of temperature (230 and 260 °C) and the solvent/feed ratio (40 and 80) were considered. The integrated system resulted in a FS yield of 19.19 ± 0.49 g/ 100 g SH, for a condition Integrated 230 °C, S/F-40, a FS yield 3.3 times greater than that obtained in the same condition with untreated soybean hulls, demonstrating the advantage of perform the process under this operating strategy (SE + SWH)</div></div>","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"216 ","pages":"Article 106448"},"PeriodicalIF":3.4,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142586193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-28DOI: 10.1016/j.supflu.2024.106423
Marco Antonio Mamani , José Manuel del Valle , Paulo Aravena , Roberto Canales
We developed a methodology to study the extraction of high-value solutes directly from suspensions of finely disrupted substrates. For that, we modelled the high-pressure phase equilibrium for the ternary (CO2 + ethanol + water) system using experimental literature data. Different compositions of hydroethanolic mixture and CO2 were loaded into an extraction vessel set at 30–35 MPa and 40–50 °C during static extraction, and a gaseous mixture with the composition of the CO2-rich gaseous phase in the extraction vessel was continuously fed during dynamic extraction. Losses of the fed hydroethanolic mixture occurred mainly during dynamic extraction (10–30 wt%) and were properly distributed to account for actual flows and compositions of experimental streams. Mostly, equilibrium conditions were reached following about 1 h of the 2-h dynamic extraction, and good reproducibility was achieved. In conclusion, equilibrium is reached in which two phases coexist in equilibrium within the extraction vessel: a water-rich liquid phase and a CO2-rich gaseous phase.
{"title":"An experimental methodology to validate the use of hydroethanolic mixtures as suspending medium / modifier for the supercritical CO2 extraction of suspensions","authors":"Marco Antonio Mamani , José Manuel del Valle , Paulo Aravena , Roberto Canales","doi":"10.1016/j.supflu.2024.106423","DOIUrl":"10.1016/j.supflu.2024.106423","url":null,"abstract":"<div><div>We developed a methodology to study the extraction of high-value solutes directly from suspensions of finely disrupted substrates. For that, we modelled the high-pressure phase equilibrium for the ternary (CO<sub>2</sub> + ethanol + water) system using experimental literature data. Different compositions of hydroethanolic mixture and CO<sub>2</sub> were loaded into an extraction vessel set at 30–35 MPa and 40–50 °C during static extraction, and a gaseous mixture with the composition of the CO<sub>2</sub>-rich gaseous phase in the extraction vessel was continuously fed during dynamic extraction. Losses of the fed hydroethanolic mixture occurred mainly during dynamic extraction (10–30 wt%) and were properly distributed to account for actual flows and compositions of experimental streams. Mostly, equilibrium conditions were reached following about 1 h of the 2-h dynamic extraction, and good reproducibility was achieved. In conclusion, equilibrium is reached in which two phases coexist in equilibrium within the extraction vessel: a water-rich liquid phase and a CO<sub>2</sub>-rich gaseous phase.</div></div>","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"216 ","pages":"Article 106423"},"PeriodicalIF":3.4,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142660692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-28DOI: 10.1016/j.supflu.2024.106441
Gricielle A. Sutil , Kátia S. Andrade , Evertan A. Rebelatto , Marcelo Lanza
The impregnation of piperine and black pepper extract into poly (L-lactic acid) (PLLA) films using supercritical CO2 was investigated. Piperine was a model to determine the influence of operating conditions of pressure (10 and 12 MPa) and temperature (40 and 50 °C) on the impregnation yield. The most favorable conditions were obtained at 10 MPa and 50 °C and were used in the incorporation of piperine and black pepper extract into 200 µm films. The addition of 5 and 10 % ethanol as cosolvent was tested during the impregnation processes of black pepper extract and piperine. The impregnated films were characterized on their thermal, mechanical, structural and surface properties. The addition of 5 % cosolvent favored the increase in piperine yield (5.6 %). The impregnation of piperine and extract using co-solvent led to an increase in the crystallinity of the films and significant changes in the mechanical properties. Supercritical technology has shown promise for the impregnation of active agents into PLLA films for potential development in food packaging applications.
{"title":"Effect of supercritical CO2 impregnation of piperine and black pepper extract on properties of poly(l-lactic acid) films","authors":"Gricielle A. Sutil , Kátia S. Andrade , Evertan A. Rebelatto , Marcelo Lanza","doi":"10.1016/j.supflu.2024.106441","DOIUrl":"10.1016/j.supflu.2024.106441","url":null,"abstract":"<div><div>The impregnation of piperine and black pepper extract into poly (L-lactic acid) (PLLA) films using supercritical CO<sub>2</sub> was investigated. Piperine was a model to determine the influence of operating conditions of pressure (10 and 12 MPa) and temperature (40 and 50 °C) on the impregnation yield. The most favorable conditions were obtained at 10 MPa and 50 °C and were used in the incorporation of piperine and black pepper extract into 200 µm films. The addition of 5 and 10 % ethanol as cosolvent was tested during the impregnation processes of black pepper extract and piperine. The impregnated films were characterized on their thermal, mechanical, structural and surface properties. The addition of 5 % cosolvent favored the increase in piperine yield (5.6 %). The impregnation of piperine and extract using co-solvent led to an increase in the crystallinity of the films and significant changes in the mechanical properties. Supercritical technology has shown promise for the impregnation of active agents into PLLA films for potential development in food packaging applications.</div></div>","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"216 ","pages":"Article 106441"},"PeriodicalIF":3.4,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142578955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dyes abundance in wastewaters poses environmental threats, and a cost-effective strategy to remediate dyed water is adsorption: this process could be enhanced using nanostructured sorbents, that expose high surface areas.
Methods
In this work, chitosan aerogel adsorbents were produced by supercritical CO2 assisted drying, working at 200 bar, 35 °C, and CO2 mass flow rate of 0.8 kg/h. FESEM images proved that the delicate biopolymeric network was intact thanks to near-zero surface tension at the interface between CO2 and the liquid, and large supercritical fluid diffusivity. Methyl Orange (MO) and Crystal Violet (CV) were used as model anionic and cationic dyes, respectively.
Significant findings
Changing dye initial concentration, chitosan aerogel showed different behavior at low and large driving forces, for both CV and MO. Adsorption experiments proved that MO could be not completely removed by aqueous solutions: whereas, CV removal was successful with removal efficiencies up to 89.0 ± 1.1 % from a 10 ppm solution, using 50 mg of aerogel. FT-IR analysis proved that chitosan active sites were more effectively involved with CV rather than MO. Kinetic analysis, carried out for both dyes, showed that the process follows a pseudo-second order kinetics, related to internal mass transfer resistances and diffusion phenomena.
{"title":"Dye removal from wastewater using nanostructured chitosan aerogels produced by supercritical CO2 drying","authors":"Alessandra Zanotti, Lucia Baldino, Stefano Cardea, Ernesto Reverchon","doi":"10.1016/j.supflu.2024.106442","DOIUrl":"10.1016/j.supflu.2024.106442","url":null,"abstract":"<div><h3>Background</h3><div>Dyes abundance in wastewaters poses environmental threats, and a cost-effective strategy to remediate dyed water is adsorption: this process could be enhanced using nanostructured sorbents, that expose high surface areas.</div></div><div><h3>Methods</h3><div>In this work, chitosan aerogel adsorbents were produced by supercritical CO<sub>2</sub> assisted drying, working at 200 bar, 35 °C, and CO<sub>2</sub> mass flow rate of 0.8 kg/h. FESEM images proved that the delicate biopolymeric network was intact thanks to near-zero surface tension at the interface between CO<sub>2</sub> and the liquid, and large supercritical fluid diffusivity. Methyl Orange (MO) and Crystal Violet (CV) were used as model anionic and cationic dyes, respectively.</div></div><div><h3>Significant findings</h3><div>Changing dye initial concentration, chitosan aerogel showed different behavior at low and large driving forces, for both CV and MO. Adsorption experiments proved that MO could be not completely removed by aqueous solutions: whereas, CV removal was successful with removal efficiencies up to 89.0 ± 1.1 % from a 10 ppm solution, using 50 mg of aerogel. FT-IR analysis proved that chitosan active sites were more effectively involved with CV rather than MO. Kinetic analysis, carried out for both dyes, showed that the process follows a pseudo-second order kinetics, related to internal mass transfer resistances and diffusion phenomena.</div></div>","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"216 ","pages":"Article 106442"},"PeriodicalIF":3.4,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142578817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-28DOI: 10.1016/j.supflu.2024.106443
Rafael V. Mota , Nayara J.N. da Silva , Eduardo G.O. Menezes , Maria Eduarda F. de Carvalho , Jean M.L. Pinheiro , Diego A. da Silva , Eloisa H. de A. Andrade , Raul N. de Carvalho Junior
This pioneering study is the first to explore the extraction of Calycolpus goetheanus using supercritical carbon dioxide (scCO2), novel approach to harnessing the bioactive potential of this Amazonian species. By examining extractions under varying temperatures (35 and 45 °C) and pressures (150, 250, and 350 bar), the research not only evaluates the yields but also uncovers significant differences in chemical composition and antioxidant activity compared to traditional hydrodistillation. Notably, the highest yield (2.11 ± 0.07 %) was achieved under 45 °C and 350 bar conditions, where n-heneicosane (34.26 %) was the dominant compound, alongside δ-cadinene, α-terpineol, and other important terpenes and fatty alcohols. The scCO2 extracts demonstrated superior antioxidant activity compared to hydrodistillation, highlighting the method's ability to preserve and concentrate bioactive compounds. This research advances the field by showcasing scCO2 as a greener and more efficient extraction technique, with potential applications in pharmaceuticals, cosmetics, and nutraceuticals, opening new pathways for the sustainable exploitation of Amazonian biodiversity.
{"title":"Determination of process parameters, chemical composition and antioxidant activity of Calycolpus goetheanus (O. Berg) extract obtained by supercritical CO2","authors":"Rafael V. Mota , Nayara J.N. da Silva , Eduardo G.O. Menezes , Maria Eduarda F. de Carvalho , Jean M.L. Pinheiro , Diego A. da Silva , Eloisa H. de A. Andrade , Raul N. de Carvalho Junior","doi":"10.1016/j.supflu.2024.106443","DOIUrl":"10.1016/j.supflu.2024.106443","url":null,"abstract":"<div><div>This pioneering study is the first to explore the extraction of Calycolpus goetheanus using supercritical carbon dioxide (scCO<sub>2</sub>), novel approach to harnessing the bioactive potential of this Amazonian species. By examining extractions under varying temperatures (35 and 45 °C) and pressures (150, 250, and 350 bar), the research not only evaluates the yields but also uncovers significant differences in chemical composition and antioxidant activity compared to traditional hydrodistillation. Notably, the highest yield (2.11 ± 0.07 %) was achieved under 45 °C and 350 bar conditions, where <em>n-</em>heneicosane (34.26 %) was the dominant compound, alongside δ-cadinene, α-terpineol, and other important terpenes and fatty alcohols. The scCO<sub>2</sub> extracts demonstrated superior antioxidant activity compared to hydrodistillation, highlighting the method's ability to preserve and concentrate bioactive compounds. This research advances the field by showcasing scCO<sub>2</sub> as a greener and more efficient extraction technique, with potential applications in pharmaceuticals, cosmetics, and nutraceuticals, opening new pathways for the sustainable exploitation of Amazonian biodiversity.</div></div>","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"216 ","pages":"Article 106443"},"PeriodicalIF":3.4,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142578816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-26DOI: 10.1016/j.supflu.2024.106432
Beatriz G. Orcón Basilio, Delia R. Verástegui Cholán, María E. Tito Silva, Fredy V. Huayta Socantaype, Joel L. Sedano Malpartida, Sandra M. Figueroa Flores, S. Mark Trujillo Navarro, Elizabeth V. Carranza López
Supercritical carbon dioxide (SC-CO2) was used as an alternative method of dyeing alpaca fiber. This study analyzes the colorfastness to laundering as a function of operating parameters. The fiber was subjected to a pretreatment (Impregnation), where it was soaked in an acidulated solution of Nylosan Yellow N-3RL dye, squeezed through a padder roller and then dyed in the SC-CO2 system. Dye concentrations of 4.228 × 10−4 g/ml and 13.032 × 10-4 g/ml were tested for pretreatment and the dyeing process was analyzed using a factorial design with variables: pressure (100 and 350 bar), temperature (60 and 90°C) and time (30 and 120 min). The colorfastness to laundering reached 4.5 on the gray scale at 13.032 × 10–4 g/ml and temperature significantly influenced the process (p-value=0.038). Colorfastness to laundering of 4 at 100 bar, 90°C and 30 min was achieved.
{"title":"Operation parameters of alpaca fiber dyeing with supercritical fluid","authors":"Beatriz G. Orcón Basilio, Delia R. Verástegui Cholán, María E. Tito Silva, Fredy V. Huayta Socantaype, Joel L. Sedano Malpartida, Sandra M. Figueroa Flores, S. Mark Trujillo Navarro, Elizabeth V. Carranza López","doi":"10.1016/j.supflu.2024.106432","DOIUrl":"10.1016/j.supflu.2024.106432","url":null,"abstract":"<div><div>Supercritical carbon dioxide (SC-CO2) was used as an alternative method of dyeing alpaca fiber. This study analyzes the colorfastness to laundering as a function of operating parameters. The fiber was subjected to a pretreatment (Impregnation), where it was soaked in an acidulated solution of Nylosan Yellow N-3RL dye, squeezed through a padder roller and then dyed in the SC-CO2 system. Dye concentrations of 4.228 × 10<sup>−4</sup> g/ml and 13.032 × 10<sup>-4</sup> g/ml were tested for pretreatment and the dyeing process was analyzed using a factorial design with variables: pressure (100 and 350 bar), temperature (60 and 90°C) and time (30 and 120 min). The colorfastness to laundering reached 4.5 on the gray scale at 13.032 × 10<sup>–4</sup> g/ml and temperature significantly influenced the process (p-value=0.038). Colorfastness to laundering of 4 at 100 bar, 90°C and 30 min was achieved.</div></div>","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"216 ","pages":"Article 106432"},"PeriodicalIF":3.4,"publicationDate":"2024-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142578819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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