Pub Date : 2026-03-13DOI: 10.1016/j.supflu.2026.106960
Ning Gu, Yun Shen, Yueyang Xu, Liming Kong, Yongping Zeng
{"title":"Phase Behavior and Molecular Structure of Thiophene/[Bmim][SCN]/supercritical CO2 Systems: A Gibbs Ensemble Monte Carlo Study","authors":"Ning Gu, Yun Shen, Yueyang Xu, Liming Kong, Yongping Zeng","doi":"10.1016/j.supflu.2026.106960","DOIUrl":"https://doi.org/10.1016/j.supflu.2026.106960","url":null,"abstract":"","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"188 1","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147447744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-11DOI: 10.1016/j.supflu.2026.106965
Jafar Javanmardi, Ali Rasoolzadeh, Amir H. Mohammadi
{"title":"Influence of Propylene Glycol on the Thermodynamics and Kinetics of Methane Hydrate Formation","authors":"Jafar Javanmardi, Ali Rasoolzadeh, Amir H. Mohammadi","doi":"10.1016/j.supflu.2026.106965","DOIUrl":"https://doi.org/10.1016/j.supflu.2026.106965","url":null,"abstract":"","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"26 1","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147447741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-01Epub Date: 2025-10-30DOI: 10.1016/j.supflu.2025.106827
Awais Khalid, Satam Alotibi
We report herein the effect of Pd loading supported over CeO2/TiO2 nanocomposite for catalytic carbonation of glycerol with CO2. The synthesized catalyst was thoroughly characterized using various spectroscopic and microscopic techniques and overserved uniformly dispersed 1.5 % Pd nanoparticles of 5–20 nm showed improved conversion of glycerol to 34 % with 60 % glycerol carbonate selectivity at 150°C. Reaction parameters, such as temperature, CO2 pressure, mmol of 2-cyanopyridine, and the reaction time, were investigated. Sheldon’s hot filtration test confirmed the catalyst’s heterogeneity with no leaching up to five consecutive cycles.
{"title":"Synthesis of glycerol carbonate via direct carbonation of glycerol in CO2 over Pd/CeO2/TiO2 catalyst","authors":"Awais Khalid, Satam Alotibi","doi":"10.1016/j.supflu.2025.106827","DOIUrl":"10.1016/j.supflu.2025.106827","url":null,"abstract":"<div><div>We report herein the effect of Pd loading supported over CeO<sub>2</sub>/TiO<sub>2</sub> nanocomposite for catalytic carbonation of glycerol with CO<sub>2</sub>. The synthesized catalyst was thoroughly characterized using various spectroscopic and microscopic techniques and overserved uniformly dispersed 1.5 % Pd nanoparticles of 5–20 nm showed improved conversion of glycerol to 34 % with 60 % glycerol carbonate selectivity at 150°C. Reaction parameters, such as temperature, CO<sub>2</sub> pressure, mmol of 2-cyanopyridine, and the reaction time, were investigated. Sheldon’s hot filtration test confirmed the catalyst’s heterogeneity with no leaching up to five consecutive cycles.</div></div>","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"229 ","pages":"Article 106827"},"PeriodicalIF":4.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145404738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-01Epub Date: 2025-11-12DOI: 10.1016/j.supflu.2025.106840
Xu Lu , Xicheng Yang , Jia Zhang , Pengpeng Zhang , Qian Liu , Feng Zhou , Yanpei Sun , Hongjuan Zhang , Dongyin Chen , Yang Jin , Lina Chen
In recent years, the remarkable bioactivities and nutritional value of Dendrobium flexicaule flowers have become increasingly evident, underscoring their potential for broad applications. However, optimal extraction techniques and their health-promoting effects remain inadequately unexplored. This study investigated the neuroprotective effects of supercritical fluid-extracted DFF extract (DFFE), identified its key constituents, and elucidated underlying mechanisms via integrated in vitro and in silico approaches. Herein, the extract was obtained using supercritical fluid extraction (SFE), which demonstrated superior efficiency in preserving thermo-labile compounds and minimizing oxidative degradation compared to conventional ethanol reflux extraction, as evidenced by enhanced recovery of unsaturated fatty acids and sterols. Gas chromatography-mass spectrometry (GC-MS) analysis identified a total of 96 chemical constituents in DFFE. Notably, DFFE significantly mitigated glutamate-induced damage in PC12 cells by reducing LDH release, ROS generation, and enhancing antioxidant enzyme activity. Network pharmacology revealed linoleic acid, hexadecenoic acid, and pentadecanoic acid as core bioactive components, targeting PPARG, GSK3β, IL6, PTGS2, and MAPK3, which modulate Alzheimer’s and TNF signaling pathways. Molecular docking demonstrated stable interactions between most bioactive components and core targets through hydrogen bonds, with binding energies predominantly less than −5 kcal/mol. Ultimately, the extraction process was optimized using a decision tree model, which highlighted temperature and pressure as crucial parameters. Overall, these findings underscore DFFE’s potential as a neuroprotective agent for functional food or therapeutic development.
{"title":"A novel extract of Dendrobium flexicaule flower: Volatile components and neuroprotective potential","authors":"Xu Lu , Xicheng Yang , Jia Zhang , Pengpeng Zhang , Qian Liu , Feng Zhou , Yanpei Sun , Hongjuan Zhang , Dongyin Chen , Yang Jin , Lina Chen","doi":"10.1016/j.supflu.2025.106840","DOIUrl":"10.1016/j.supflu.2025.106840","url":null,"abstract":"<div><div>In recent years, the remarkable bioactivities and nutritional value of <em>Dendrobium flexicaule</em> flowers have become increasingly evident, underscoring their potential for broad applications. However, optimal extraction techniques and their health-promoting effects remain inadequately unexplored. This study investigated the neuroprotective effects of supercritical fluid-extracted DFF extract (DFFE), identified its key constituents, and elucidated underlying mechanisms via integrated <em>in vitro</em> and <em>in silico</em> approaches. Herein, the extract was obtained using supercritical fluid extraction (SFE), which demonstrated superior efficiency in preserving thermo-labile compounds and minimizing oxidative degradation compared to conventional ethanol reflux extraction, as evidenced by enhanced recovery of unsaturated fatty acids and sterols. Gas chromatography-mass spectrometry (GC-MS) analysis identified a total of 96 chemical constituents in DFFE. Notably, DFFE significantly mitigated glutamate-induced damage in PC12 cells by reducing LDH release, ROS generation, and enhancing antioxidant enzyme activity. Network pharmacology revealed linoleic acid, hexadecenoic acid, and pentadecanoic acid as core bioactive components, targeting PPARG, GSK3β, IL6, PTGS2, and MAPK3, which modulate Alzheimer’s and TNF signaling pathways. Molecular docking demonstrated stable interactions between most bioactive components and core targets through hydrogen bonds, with binding energies predominantly less than −5 kcal/mol. Ultimately, the extraction process was optimized using a decision tree model, which highlighted temperature and pressure as crucial parameters. Overall, these findings underscore DFFE’s potential as a neuroprotective agent for functional food or therapeutic development.</div></div>","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"229 ","pages":"Article 106840"},"PeriodicalIF":4.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145509479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-01Epub Date: 2025-11-12DOI: 10.1016/j.supflu.2025.106841
Iván Navarro-Cárdenas, Andreas Kilzer, Eckhard Weidner, Marcus Petermann
Conventional catalytic hydrogenation of oils is essentially constrained by mass-transfer resistance because of the poor solubility of hydrogen in liquid-phase substrates. Supercritical fluids (SCFs) offer a solution by creating a single, homogeneous reaction medium that dissolves both hydrogen and high-molecular-weight oils, thus overcoming the interfacial transport limitations. This review synthesizes several research to establish a unified framework for the supercritical hydrogenation of different feedstocks, including heavy oils, vegetable oils, and emerging streams like bio- and plastic-derived pyrolysis oils. The central goal of this work is to provide a deep understanding of phase behavior which is a critical aspect of the process design, directly influencing reaction rates, selectivity, and overall efficiency. By integrating principles of thermodynamics, heat and mass transfer, catalysis selection, and reactor design, this review provides applicable design metrics for developing a more suitable upgrading technology with higher space yield times for a wide spectrum of complex oils.
{"title":"Phase behavior in heterogeneous catalytic hydrogenation of oils in supercritical fluids","authors":"Iván Navarro-Cárdenas, Andreas Kilzer, Eckhard Weidner, Marcus Petermann","doi":"10.1016/j.supflu.2025.106841","DOIUrl":"10.1016/j.supflu.2025.106841","url":null,"abstract":"<div><div>Conventional catalytic hydrogenation of oils is essentially constrained by mass-transfer resistance because of the poor solubility of hydrogen in liquid-phase substrates. Supercritical fluids (SCFs) offer a solution by creating a single, homogeneous reaction medium that dissolves both hydrogen and high-molecular-weight oils, thus overcoming the interfacial transport limitations. This review synthesizes several research to establish a unified framework for the supercritical hydrogenation of different feedstocks, including heavy oils, vegetable oils, and emerging streams like bio- and plastic-derived pyrolysis oils. The central goal of this work is to provide a deep understanding of phase behavior which is a critical aspect of the process design, directly influencing reaction rates, selectivity, and overall efficiency. By integrating principles of thermodynamics, heat and mass transfer, catalysis selection, and reactor design, this review provides applicable design metrics for developing a more suitable upgrading technology with higher space yield times for a wide spectrum of complex oils.</div></div>","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"229 ","pages":"Article 106841"},"PeriodicalIF":4.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145509466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-01Epub Date: 2025-10-19DOI: 10.1016/j.supflu.2025.106824
Yuto Asai, Ikuo Ushiki
Mesoporous silica is a promising drug delivery carrier owing to its high surface area, tunable pores, and ability to stabilize amorphous drugs. In this study, supercritical fluid deposition (SCFD) using supercritical CO2 (15 MPa) was employed to load ibuprofen and ketoprofen into MCM-48 mesoporous silica. The effects of drug type, temperature (313 K to 333 K), and silica framework were evaluated systematically. Transmission electron microscopy (TEM) and nitrogen adsorption confirmed that the three-dimensional cubic mesostructure of MCM-48 remained intact after impregnation. Fourier-transform infrared spectroscopy (FT-IR), and thermogravimetric analysis (TGA) verified the successful incorporation, with distinct thermal events indicating external and pore-confined adsorption. Ibuprofen consistently achieved higher loading than ketoprofen, driven by its greater solubility in supercritical CO2, indicating that solubility is the dominant factor over surface affinity. Temperature had only a modest influence owing to the opposing effects of decreased CO2 density and reduced competitive CO2 adsorption at higher temperatures. Compared with SBA-15, MCM-48 exhibited superior uptake across all conditions, which was attributed to its larger surface area and interconnected pore network. These results demonstrate that SCFD enables the efficient, solvent-free incorporation of active compounds while preserving mesostructural integrity, offering guidance for the design of high-performance mesoporous carriers in pharmaceutical and related applications.
介孔二氧化硅由于其高表面积、可调节的孔隙和稳定非晶药物的能力，是一种很有前途的药物递送载体。本研究采用超临界CO2（15 MPa）超临界流体沉积法（SCFD）将布洛芬和酮洛芬分别装载到MCM-48介孔二氧化硅中。系统评价了药物类型、温度（313 K ~ 333 K）和二氧化硅骨架的影响。透射电镜（TEM）和氮气吸附证实，浸渍后MCM-48的三维立方细观结构保持完整。傅里叶变换红外光谱（FT-IR）和热重分析（TGA）证实了成功的掺入，不同的热事件表明外部和孔隙限制吸附。布洛芬始终比酮洛芬获得更高的负载，这是因为它在超临界CO2中的溶解度更高，这表明溶解度是比表面亲和力更重要的因素。温度的影响不大，因为在较高温度下，二氧化碳密度降低和竞争性二氧化碳吸附减少会产生相反的影响。与SBA-15相比，MCM-48在所有条件下都表现出更好的吸收率，这归因于其更大的表面积和相互连接的孔隙网络。这些结果表明，SCFD能够在保持介孔结构完整性的同时高效、无溶剂地结合活性化合物，为制药和相关应用中高性能介孔载体的设计提供指导。
{"title":"Evaluation of drug loading onto MCM-48 via supercritical CO2 deposition: Effects of drug type, temperature, and silica structure","authors":"Yuto Asai, Ikuo Ushiki","doi":"10.1016/j.supflu.2025.106824","DOIUrl":"10.1016/j.supflu.2025.106824","url":null,"abstract":"<div><div>Mesoporous silica is a promising drug delivery carrier owing to its high surface area, tunable pores, and ability to stabilize amorphous drugs. In this study, supercritical fluid deposition (SCFD) using supercritical CO<sub>2</sub> (15 MPa) was employed to load ibuprofen and ketoprofen into MCM-48 mesoporous silica. The effects of drug type, temperature (313 K to 333 K), and silica framework were evaluated systematically. Transmission electron microscopy (TEM) and nitrogen adsorption confirmed that the three-dimensional cubic mesostructure of MCM-48 remained intact after impregnation. Fourier-transform infrared spectroscopy (FT-IR), and thermogravimetric analysis (TGA) verified the successful incorporation, with distinct thermal events indicating external and pore-confined adsorption. Ibuprofen consistently achieved higher loading than ketoprofen, driven by its greater solubility in supercritical CO<sub>2</sub>, indicating that solubility is the dominant factor over surface affinity. Temperature had only a modest influence owing to the opposing effects of decreased CO<sub>2</sub> density and reduced competitive CO<sub>2</sub> adsorption at higher temperatures. Compared with SBA-15, MCM-48 exhibited superior uptake across all conditions, which was attributed to its larger surface area and interconnected pore network. These results demonstrate that SCFD enables the efficient, solvent-free incorporation of active compounds while preserving mesostructural integrity, offering guidance for the design of high-performance mesoporous carriers in pharmaceutical and related applications.</div></div>","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"229 ","pages":"Article 106824"},"PeriodicalIF":4.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145364356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-01Epub Date: 2025-11-12DOI: 10.1016/j.supflu.2025.106842
Zeynep Caglar , Busra Kilic , Halil Murat Aydin
Peripheral nerve injuries are a major public health concern. The slow self-regeneration of the complex structure of the peripheral nervous system significantly impacts functional recovery. For this reason, studies on nerve tissue engineering for peripheral nerve repair are critical. Here, we constructed a gelMA-based decellularized SIS hybrid construct to promote functional regeneration after peripheral nerve injury. A supercritical carbon dioxide (scCO2) decellularization protocol was developed for bovine small intestinal submucosa (SIS) decellularization. A conventional method involving the combinations of physical, chemical, and enzymatic treatments was used for evaluating the efficiency of the scCO2 technology for SIS decellularization. The efficiency of decellularization methods was evaluated using both qualitative and quantitative analyses. In this regard, it was shown that the scCO2 technology was an efficient and high-yielding method for the decellularization of SIS. Then, SIS was incubated with gelMA solutions to obtain hybrid hydrogels. FT-IR and SEM were used to prove the success of hybrid tissue scaffold synthesis as well as to investigate structural changes. The water retention capacity, degradation properties and mechanical strength of the hybrid scaffolds were investigated and compared with the acellular SIS. Lastly the ability of hybrid membranes to induce neural cell adhesion and proliferation was evaluated via in vitro cell culture of Schwann cells in terms of cell viability, proliferation and morphological changes.
{"title":"The development of GelMA based hydrogels combined with acellular small intestinal submucosa for peripheral nerve injuries","authors":"Zeynep Caglar , Busra Kilic , Halil Murat Aydin","doi":"10.1016/j.supflu.2025.106842","DOIUrl":"10.1016/j.supflu.2025.106842","url":null,"abstract":"<div><div>Peripheral nerve injuries are a major public health concern. The slow self-regeneration of the complex structure of the peripheral nervous system significantly impacts functional recovery. For this reason, studies on nerve tissue engineering for peripheral nerve repair are critical. Here, we constructed a gelMA-based decellularized SIS hybrid construct to promote functional regeneration after peripheral nerve injury. A supercritical carbon dioxide (scCO<sub>2</sub>) decellularization protocol was developed for bovine small intestinal submucosa (SIS) decellularization. A conventional method involving the combinations of physical, chemical, and enzymatic treatments was used for evaluating the efficiency of the scCO<sub>2</sub> technology for SIS decellularization. The efficiency of decellularization methods was evaluated using both qualitative and quantitative analyses. In this regard, it was shown that the scCO<sub>2</sub> technology was an efficient and high-yielding method for the decellularization of SIS. Then, SIS was incubated with gelMA solutions to obtain hybrid hydrogels. FT-IR and SEM were used to prove the success of hybrid tissue scaffold synthesis as well as to investigate structural changes. The water retention capacity, degradation properties and mechanical strength of the hybrid scaffolds were investigated and compared with the acellular SIS. Lastly the ability of hybrid membranes to induce neural cell adhesion and proliferation was evaluated via <em>in vitro</em> cell culture of Schwann cells in terms of cell viability, proliferation and morphological changes.</div></div>","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"229 ","pages":"Article 106842"},"PeriodicalIF":4.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145509470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-01Epub Date: 2025-11-08DOI: 10.1016/j.supflu.2025.106835
Marta Gallo, Marco Armandi, Fabiana Mangano, Silvia Ronchetti, Mauro Banchero, Luigi Manna
To overcome climate challenges, emerging CO2 capture technologies focus on innovative solid sorbents, like aerogels. Silica aerogels, in particular, have emerged as an exceptional class of materials with unique properties even though their adsorption selectivity towards CO2, and their thermal and mechanical properties are limited. In this research, a hybrid silica-alumina aerogel has been prepared, to merge the elevated surface area typical of silica with the basic character (favorable to CO2 adsorption) and the high thermal and mechanical resistance typical of alumina. For the first time, these silica-alumina aerogels were functionalized with 3-aminopropyltriethoxysilane (APTES) amino groups through a one-pot process. This approach was chosen to directly introduce functional groups during gel formation, reducing the number of post-synthesis steps. The functionalization with amino groups aims to strengthen the interactions with CO₂ molecules via acid–base interactions, thus enhancing adsorption capacity and selectivity. Three samples with increasing APTES content as well as a reference without any functionalization were prepared and characterized in terms of physico-chemical and adsorption properties. The results of CO2 and N2 adsorption tests as well as in situ FTIR suggest that low functionalization does not confer a significant advantage in CO2 capture. Higher APTES contents, instead, lead to a significant increase in the total quantity of adsorbed CO2 and in higher selectivity over N2 (calculated according to the Ideal Adsorbed Solution Theory). Moreover, also the strength of interaction increases, since not only physisorption, but also chemisorption takes place.
{"title":"Silica-alumina aerogels functionalized with amino-groups for the adsorption of CO2","authors":"Marta Gallo, Marco Armandi, Fabiana Mangano, Silvia Ronchetti, Mauro Banchero, Luigi Manna","doi":"10.1016/j.supflu.2025.106835","DOIUrl":"10.1016/j.supflu.2025.106835","url":null,"abstract":"<div><div>To overcome climate challenges, emerging CO<sub>2</sub> capture technologies focus on innovative solid sorbents, like aerogels. Silica aerogels, in particular, have emerged as an exceptional class of materials with unique properties even though their adsorption selectivity towards CO<sub>2</sub>, and their thermal and mechanical properties are limited. In this research, a hybrid silica-alumina aerogel has been prepared, to merge the elevated surface area typical of silica with the basic character (favorable to CO<sub>2</sub> adsorption) and the high thermal and mechanical resistance typical of alumina. For the first time, these silica-alumina aerogels were functionalized with 3-aminopropyltriethoxysilane (APTES) amino groups through a one-pot process. This approach was chosen to directly introduce functional groups during gel formation, reducing the number of post-synthesis steps. The functionalization with amino groups aims to strengthen the interactions with CO₂ molecules via acid–base interactions, thus enhancing adsorption capacity and selectivity. Three samples with increasing APTES content as well as a reference without any functionalization were prepared and characterized in terms of physico-chemical and adsorption properties. The results of CO<sub>2</sub> and N<sub>2</sub> adsorption tests as well as <em>in situ</em> FTIR suggest that low functionalization does not confer a significant advantage in CO<sub>2</sub> capture. Higher APTES contents, instead, lead to a significant increase in the total quantity of adsorbed CO<sub>2</sub> and in higher selectivity over N<sub>2</sub> (calculated according to the Ideal Adsorbed Solution Theory). Moreover, also the strength of interaction increases, since not only physisorption, but also chemisorption takes place.</div></div>","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"229 ","pages":"Article 106835"},"PeriodicalIF":4.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145473167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-01Epub Date: 2025-10-29DOI: 10.1016/j.supflu.2025.106825
Guangyu Liu , Xinxin Fan , Cailin Wang , Junwen Chen , Shengzhu Zhang , Mingzhuo Li , Qihui Hu , Yuxing Li
Phase transitions in long-distance CO2 pipelines are inevitable, yet their coupled effects on corrosion under real pipeline flow conditions remain inadequately understood. This study systematically investigates the influence of phase transition and flow velocity on the corrosion mechanisms of X65 steel in CO2 pipelines through corrosion experiments, microscopic characterization of corrosion product films, and theoretical modeling of droplet spreading and pit development. The findings reveal that flow conditions transform the dominant corrosion mode in the phase transition environment from pitting corrosion in static conditions to uniform corrosion in dynamic conditions. This shift primarily arises from variations in flow rate and CO2 density, which alter droplet size distribution on the steel surface. Most droplets become smaller than the critical radius required for downward pit propagation, leading to lateral pit expansion rather than deepening. Consequently, uniform corrosion is intensified, while pitting corrosion is mitigated. Furthermore, changes in wall shear stress and droplet dynamics during phase transitions disrupt the structural integrity of corrosion products, further exacerbating uniform corrosion.
{"title":"A mechanistic model for X65 steel corrosion in supercritical CO2 flow and phase change pipeline transportation environment","authors":"Guangyu Liu , Xinxin Fan , Cailin Wang , Junwen Chen , Shengzhu Zhang , Mingzhuo Li , Qihui Hu , Yuxing Li","doi":"10.1016/j.supflu.2025.106825","DOIUrl":"10.1016/j.supflu.2025.106825","url":null,"abstract":"<div><div>Phase transitions in long-distance CO<sub>2</sub> pipelines are inevitable, yet their coupled effects on corrosion under real pipeline flow conditions remain inadequately understood. This study systematically investigates the influence of phase transition and flow velocity on the corrosion mechanisms of X65 steel in CO<sub>2</sub> pipelines through corrosion experiments, microscopic characterization of corrosion product films, and theoretical modeling of droplet spreading and pit development. The findings reveal that flow conditions transform the dominant corrosion mode in the phase transition environment from pitting corrosion in static conditions to uniform corrosion in dynamic conditions. This shift primarily arises from variations in flow rate and CO<sub>2</sub> density, which alter droplet size distribution on the steel surface. Most droplets become smaller than the critical radius required for downward pit propagation, leading to lateral pit expansion rather than deepening. Consequently, uniform corrosion is intensified, while pitting corrosion is mitigated. Furthermore, changes in wall shear stress and droplet dynamics during phase transitions disrupt the structural integrity of corrosion products, further exacerbating uniform corrosion.</div></div>","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"229 ","pages":"Article 106825"},"PeriodicalIF":4.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145383119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-01Epub Date: 2025-10-06DOI: 10.1016/j.supflu.2025.106801
Minxing Zhang , Lidia Montero , Jose A. Mendiola , Elena Ibáñez
Ilex guayusa, a traditional Amazonian plant rich in caffeine and polyphenols, has attracted interest for its antioxidant and neuroprotective properties. This study evaluates the potential of green compressed fluid extraction techniques to recover bioactive compounds from I. guayusa leaves using environmentally friendly solvents: pressurized liquid extraction (PLE), gas-expanded liquids (GXL), and supercritical fluid extraction (SFE). A mixture design approach combining CO2, ethanol, water, and 2-methyltetrahydrofuran (2-MTHF) in different proportions as solvents was applied to optimize extraction conditions. Among the tested methods, GXL extraction yielded the highest phenolic content and demonstrated superior antioxidant (ABTS and DPPH) and anti-inflammatory (inhibition of lipoxigenase, LOX) activities. Conventional water maceration showed stronger cholinesterase inhibition, suggesting complementary neuroprotective potential. Chemical profiling (HPLC-DAD-ESI-MS/MS) of the optimized extract confirmed the presence of phenolic acids and flavonoids associated with the observed bioactivities. These findings highlight the effectiveness of compressed fluid-based green extraction for obtaining multifunctional phytochemicals from I. guayusa, with promising applications in functional foods and nutraceuticals.
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