Journal of Science: Advanced Materials and Devices最新文献

The employment of biomolecular templates for the synthesizing nanohybrid constructs is expanding, driven by their prospective uses in biosensing and biomedical fields. Gold nanoparticles (AuNPs) and, in particular, their assemblies are especially preferred for Surface Enhanced Raman Spectroscopy (SERS) because of their ability to amplify Raman signals through localized surface plasmon resonances, thus enabling the detection of molecules at exceedingly low concentrations. Our investigative approach is dedicated to studing the role of cysteine mutants in the nucleation and assembly of AuNPs on Tobacco mosaic virus (TMV-C, carrying T158C mutation) scaffolds. Employing biomineralization and direct grafting methods, we synthesized these nanohybrids and examined them using conventional transmission electron microscopy (TEM), in situ liquid TEM, and fluorescence spectroscopy. We demonstrated that the syntheses obtained with TMV-C give denser plasmonic nanostructures, with is ideal for SERS applications. The SERS performances of these novel nanohybrids with various AuNPs sizes and densities were evaluated, revealing excellent enhancement factors for the nanosystems obtained by direct grafting that highlight their potential for the detection of biomolecules in solution.

In the current work, we report the bio-inspired formulation of silver NPs fabricated over Arabic gum (AG) functionalized magnetic nanocomposite (Fe₃O₄@AG/Ag NPs) for the treatment of cervical cancer. In the stepwise modification approach, the pre-synthesized Fe₃O₄ NPs were encapsulated by the Arabic gum polar organomolecules, followed by the decoration of in-situ green synthesized silver NPs over the composite. The final bio-material was characterized by various analytical techniques such as XRD, EDX, ICP-OES, TEM, FE-SEM, and FT-IR. The FE-SEM findings validate the spherical shape of the Fe₃O₄@AG/Ag NPs, which range in size from 20 to 35 nm. An assessment was conducted on the characteristics of Fe₃O₄@AG/Ag NPs in relation to prevalent human cervical cancer cells. The DPPH free radical antioxidant assay demonstrates the notable antioxidant characteristics of Fe3O4@AG/Ag NPs. The Fe₃O₄@AG/Ag NPs exhibited IC₅₀ values of 115, 90, 119, and 80 when tested against SiHa, C-33 A, Ca Ski, and LM-MEL-41 cells, respectively. The anti-human cervical cancer effect of Fe₃O₄@AG/Ag NPs appears to be a result of their antioxidant properties. According to the findings mentioned above, there is a potential for the newly created Fe₃O₄@AG/Ag NPs to be utilized as an innovative chemotherapeutic treatment or supplement for managing cervical cancer after the conclusion of clinical trials with human participants.

The present study describes ultrasonically produced ternary composite material composed of carbon nitride nanosheets, zirconium, and titanium oxides for elimination of copper ions. The formation of monoclinic ZrO₂, anatase TiO₂, and g-C₃N₄ phases with respective crystallite sizes 6, 11, 13 nm were verified by the X-ray diffraction technique. The dispersion of the metal oxides nanoparticles with the graphitic nanosheets, the elemental composition of Zr, Ti, O, C and N, and the characteristic functional groups were verified respectively by TEM, EDX, and FTIR analysis that confirmed the successful formation and composition of the nanocomposite TiO₂–ZrO₂@g-C₃N₄ (TZCN). The good porosity of the composite that show a surface area, pore volume, and pore diameter values of 47.42 m²/g, 0.056 cm³ g⁻¹, and 20.3 Å that nominate it for adsorption application. The adsorption capabilities of the nanocomposite were studied for copper ion removal from an aqueous solution, as well as the impacts of pH and starting Cu²⁺ concentration. The results show that the adsorption process is pH and starting concentration-dependent, with a maximum adsorption capacity of 447.8 mg/g. The Cu²⁺ adsorption is a monolayer chemisorption process that is well described by the Langmuir adsorption model and follows pseudo-second-order kinetics. Moreover, a plausible mechanism for Cu²⁺ ion adsorption on the surface of TZCN nanocomposite particles is proposed.

Printed electronics, fueled by graphene's conductivity and flexibility, are revolutionizing wearable technology, surpassing copper's limitations in cost, signal quality, size, and environmental impact. Graphene-based inks are positioned to lead in this domain, offering cost-effective solutions directly applicable to materials such as textiles and paper. However, graphene encounters a primary drawback due to its lack of an energy band gap, constraining its potential applications in various electronic devices. In this study, we present a novel formulation of a superconductive, flexible leather graphene antenna utilizing a tri-nanocomposite structure of Graphene Nanoplatelet/Silver/Copper (GNP/Ag/Cu), covering a wideband bandwidth from 5.2 GHz to 8.5 GHz. The electrical conductivity of the GNP/Ag/Cu sample was assessed using the four-point probe method. With each additional layer, conductivity increased from 10.473 × 10⁷ S/m to 40.218 × 10⁷ S/m, demonstrating a direct correlation between conductivity and antenna gain. The study evaluates the efficacy of various thicknesses of conductive Graphene (GNP/Ag/Cu) ink on drill fabric. Safety assurance is provided through specific absorption rate (SAR) testing, indicating 0.84 W/kg per 10 g of tissue for an input power of 0.5 W, in compliance with ICNIRP standards for wearable device safety. Additionally, a morphological analysis of the antenna was conducted, showcasing its potential for efficient signal transmission in wearable electronic devices.

Due to the non-specific distribution of drugs in the body and the low concentration at the tumor site in traditional chemotherapy, there are challenges associated with significant side effects and tumor resistance. Therefore, a drug delivery system (DDS) urgently needs to be developed that can precisely target tumors. Metal-organic frameworks (MOFs) possess advantageous characteristics derived from organic and inorganic materials, including small particle size, large specific surface area, high drug loading capacity, adjustable structure and pore size, as well as ease of modification. Consequently, MOFs offer unique advantages for designing active targeting, passive targeting, and stimulus-responsive targeting strategies and have become a hot topic of current research on tumor-targeted drug delivery systems. This review will elaborate on the application of MOFs in tumor-targeted drug delivery systems from the perspective of different targeting strategies. We hope that this paper can provide assistance for tumor-targeted therapy.

Ethephon (ETH) is a plant growth regulator extensively utilized in agriculture, but its overuse is associated with several health issues. However, detecting ETH sensitively and easily in the field is challenging due to the complexity and time-consuming operation of current approaches. In this study, we synthesized aluminum-based metal-organic frameworks (CAU-1) as fluorescent probes for the detection of ETH in fruit. ETH exposure enhanced and shifted the light green fluorescence of CAU-1 to blue through high absorption of phosphate by electrostatic attraction. We observed a linear correlation between fluorescent intensity and ETH concentration ranging from 2 mg/L to 400 mg/L, with the lowest detection limit at 1 mg/L. This fluorescent analysis exhibited good selectivity towards ETH. To facilitate easy identification of samples in the field, we designed a fluorescent paper-based platform with a logic gate operation, allowing visual distinction of samples containing ETH. We applied this platform to monitor ETH in various fruits, including apples, pears, and tomatoes, through fluorescent spectrum, and visual detection. The platform offered simplicity, speed, ease of use and sensitivity, providing a promising future for ETH detection in agriculture.

Significal challenges exist to bacterial infection wound healing. The bacterial infection and inflammation generated by oxidative stress inevitably hinder the process of wound healing. Ag₆Cu₂ nanoclusters in this study were successfully prepared and displayed excellent physiological stability. Noticeably, Ag₆Cu₂ nanoclusters exhibited efficient therapeutic potentials for accelerating the process of wound healing, which had good biosafety under the appropriate concentration. The treatment of Ag₆Cu₂ was able to suppress the bacterial proliferation by destructing the bacterial, resulting in the secondary release of bacterial contents and to exert anti-inflammatory properties via scavenging the overproduction of reactive oxygen species and upregulating the expression of Nrf2 as well as its downstream genes including HO-1 and NQO1. In-vivo studies further validated the efficient therapeutic effects of Ag₆Cu₂ nanoclusters by inhibiting the activation of the cascade of inflammatory factors and the proliferation of bacteria as a novel agent in a nano scale for accelerating the process of wound healing.

Light–matter interaction operating in the strong coupling regime offers wide prospects of applications going from nano-photonics to quantum communications. The most practical implementations are to embed the active matter into Fabry–Perot microcavities or photonic crystals. In this work we focus on the strong coupling of two-dimensional (2D) perovskite in 1D grating waveguide. We use rigorous coupled wave analysis to simulate electromagnetic wave confinement in the 1D waveguide. Various sets of waveguide geometrical parameters are examined to achieve the strong coupling regime for three different configurations of the active layer in the waveguide. To extract quantitatively the relevant physical parameters, such as strength of light–matter interaction, we develop a Hamiltonian formalism to reproduce results obtained by simulation. It is shown that the strongest interaction is to have the active layer inserted in the main slab of the waveguide. It is, however, still weaker by about 20% as compared to the use of Fabry–Perot microcavities.

Supercapacitors with the advantages of high power density and rapid discharging rate have widespread applications in energy storage. Nevertheless, their development is hindered by the limitation of low specific capacity. Traditional approaches to enhance specific capacity primarily involve incorporating foreign atoms and blending with additional reactive substances. Herein, a photo-assisted supercapacitor electrode material (GN/MnO₂ nanocomposite) with excellent capacity is developed. As a photoactive material, graphene generates electrons and holes with photoirradiation. As the photogenerated carriers increase, electrons are separated from the holes and stored as charges. Photoirradiation is the driving force that promotes the energy storage and conversion of supercapacitors. Although there are many reports on GN/MnO₂ composites, there are still few reports on the photo-assisted energy storage of this composite material. The specific capacity of this photo-assisted GN/MnO₂ electrode materials could reach 210 F/g with photoirradiation. It was higher than that without photoirradiation (170 F/g). The development of this study provides important theoretical guidance and practical significance for the research of photo-assisted energy storage materials, and plays a significant role in advancing the progress of energy storage devices with high specific capacity.

The research for non-fluorinated polymeric electrolytes able to operate at temperatures of 80–120 °C, the so-called “conductivity gap”, is becoming central. Within this frame, the present work discusses the investigation of innovative self-assembling polybenzimidazole/sulfonated graphene oxide (PBI/SGO) composite membranes. A set of five samples, characterized by never-explored PBI-to-SGO mass ratios between 3:1 and 1:3, is studied through surface and cross-sectional SEM, XRD, ATR-FTIR spectroscopy, and TGA. The experimental outcomes reveal the reciprocal compatibility between PBI and SGO, whose main features appear to be evenly distributed within the composites. Water immersion tests demonstrate the excellent interplay between the membranes and the aqueous environment. EIS experiments, performed with the in-plane and through-plane configurations, disclose the improvement of the proton transfer ability (σ) in both directions. At 120 °C, PBI/SGO 1:2 achieves the highest in-plane σ of 0.113 S cm⁻¹, while PBI/SGO 1:3 shows the best through-plane σ of 0.025 S cm⁻¹. The preference toward planar proton migration is confirmed by the computation of the anisotropy factor, which is attenuated to ≈0.5 with the aid of temperature. Based on these findings, the composites with large SGO content seem to possess great potential as alternative non-fluorinated proton exchange membranes.