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An in depth investigation on device-to-device communication in heterogeneous networks: opportunities and challenges 异构网络中设备对设备通信的深入研究:机遇与挑战
IF 1.9 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2025-12-17 DOI: 10.1016/j.mex.2025.103777
Amjad Ali , Aqsa Zehra , Muhammad Nafees , Muhammad Awais Amin
Accurate data from appropriate areas and in rural areas collect reliably and quickly with the help of UAVs. UAVs are used to gather any type of information either from land, sea, or air. The communication between UAV to UAV and UAV to the ground requires some linkage or a path for transmission. Device-to-device transmission is used to offload traffic in a congestion network. However, a D2D transmission is based on multiple networks. All these networks are collectively discussed in this paper included; cellular, 5G, military, ad-hoc, IoT, Social, and public safety scenarios. A variety of advantages in terms of reliability, latency, spectrum efficiency, energy efficiency, interference mitigation, high altitude, power optimization, autonomous relaying, increased throughput, high data rates, privacy, security, mode selection, FANET, MANET, VANET, coverage extension, and covert communication is given in this paper. Eventually, in this paper, we provide all the opportunities and challenges in D2D transmission over contrasting network domains.
在无人机的帮助下,从适当地区和农村地区可靠、快速地收集准确的数据。无人机用于从陆地、海上或空中收集任何类型的信息。无人机与无人机之间以及无人机与地面之间的通信需要一定的联动或传输路径。设备到设备传输用于在拥塞网络中分流流量。然而,D2D传输是基于多个网络的。本文对这些网络进行了综合讨论,包括:蜂窝、5G、军事、ad-hoc、物联网、社会和公共安全场景。本文给出了在可靠性、延迟、频谱效率、能源效率、干扰缓解、高海拔、功率优化、自主中继、增加吞吐量、高数据速率、隐私、安全、模式选择、FANET、MANET、VANET、覆盖扩展和隐蔽通信方面的各种优势。最后,在本文中,我们提供了在不同网络域上D2D传输的所有机遇和挑战。
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引用次数: 0
Knowledge, support, and networking for Phelan-McDermid syndrome: a study protocol 费伦-麦克德米德综合征的知识、支持和网络:一项研究方案
IF 1.9 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2025-12-16 DOI: 10.1016/j.mex.2025.103771
Luca Colnaghi , Giulia Villa , Ilaria Marcomini , Andrea Poliani , Maya Fedeli , Claudio Losi , Debora Rosa , Duilio Fiorenzo Manara

Background

Phelan-McDermid syndrome (PMS) is a rare neurodevelopmental disorder caused by deletions in chromosome 22q13.3 or pathogenic variants in the SHANK3 gene. Individuals present with intellectual disability, autism-spectrum traits, seizures, gastrointestinal and motor issues, and sleep disturbances, requiring lifelong multidisciplinary care. In Italy, PMS care is fragmented and unevenly distributed, with families often providing intensive home-based support at high personal, financial, and social costs.

Methods

This national participatory Citizen-Science study, conducted with the Italian Phelan-McDermid Syndrome Association (AISPHEM), will engage informal caregivers of individuals with genetically confirmed PMS across Italy. A qualitative phase using semi-structured online interviews will explore caregiving experiences, unmet needs, barriers to care, coping strategies, and social isolation. Insights will guide the creation of the first Italian PMS registry, capturing longitudinal clinical, socio-demographic, and caregiver-related data.

Expected Results & Conclusions

The project will generate novel evidence on caregiver needs, develop the first national PMS registry, and produce a service map to support equitable, coordinated PMS care and a stronger national caregiver network in Italy.
phan - mcdermid综合征(PMS)是一种罕见的神经发育障碍,由染色体22q13.3缺失或SHANK3基因的致病性变异引起。患有智力残疾、自闭症谱系特征、癫痫、胃肠道和运动问题以及睡眠障碍的个体,需要终身多学科护理。在意大利,经前症候群护理支离破碎,分布不均,家庭往往以高昂的个人、经济和社会成本提供密集的家庭支持。方法:这项与意大利费伦-麦克德米德综合征协会(AISPHEM)合作进行的全国性参与性公民科学研究将招募意大利各地经遗传证实的经前症候群患者的非正式护理人员。使用半结构化在线访谈的定性阶段将探讨护理经验、未满足的需求、护理障碍、应对策略和社会孤立。洞察将指导创建第一个意大利经前症候群注册,捕获纵向临床,社会人口统计和护理相关数据。预期结果和结论该项目将提供有关护理人员需求的新证据,建立首个全国经前综合症登记处,并绘制服务地图,以支持意大利公平、协调的经前综合症护理和更强大的全国护理人员网络。
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引用次数: 0
Feasibility study of transcranial direct current stimulation (tDCS) efficacy in patients with neurogenic dysphagia: Study Protocol 经颅直流电刺激(tDCS)治疗神经性吞咽困难的可行性研究:研究方案
IF 1.9 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2025-12-16 DOI: 10.1016/j.mex.2025.103768
Carolina Fiorin Anhoque , Bárbara Aguiar do Sacramento da Silva , Luana Ximenes Comarela , Amanda Mezabarba Raggazzi , Walter Gomes da Silva Filho , Fernanda Moura Vargas Dias , Fernando Zanela da Silva Arêas
Non-invasive brain stimulation (NIBS) techniques have shown increasing scientific relevance due to their potential positive effects across several health domains, including rehabilitation and clinical treatment. Among these techniques, transcranial direct current stimulation (tDCS) has emerged as a promising approach for the treatment of various neurological symptoms and conditions. Specifically, tDCS has shown potential benefits in speech therapy, hearing, voice modulation, and particularly in the treatment of neurogenic dysphagia. This feasibility study aims to assess the implementation of tDCS in patients with neurogenic dysphagia and to determine whether a future randomized controlled trial (RCT) is justified. The study will be conducted at the Neurorehabilitation and Neuromodulation Laboratory, located at the Interprofessional Health Clinic School (CEIS) of the Federal University of Espírito Santo, Brazil. Twelve patients will be recruited by convenience sampling and will undergo eight 30-minute tDCS sessions (twice a week over four weeks). Swallowing function will be assessed using the Dysphagia Risk Evaluation Protocol (PARD), the Eating Assessment Tool (EAT-10), and the Quality of Life in Swallowing Disorders Protocol (SWAL-QOL) before and after the intervention. This protocol offers preliminary insights into the clinical feasibility of tDCS for dysphagia and contributes to the development of future clinical trials in this field.
由于非侵入性脑刺激技术在包括康复和临床治疗在内的多个健康领域具有潜在的积极作用,其科学相关性日益增强。在这些技术中,经颅直流电刺激(tDCS)已成为治疗各种神经症状和疾病的一种有前途的方法。具体来说,tDCS在语言治疗、听力、语音调节,特别是神经源性吞咽困难的治疗中显示出潜在的益处。这项可行性研究旨在评估tDCS在神经源性吞咽困难患者中的实施情况,并确定未来的随机对照试验(RCT)是否合理。该研究将在位于巴西圣Espírito联邦大学跨专业健康诊所学院(CEIS)的神经康复和神经调节实验室进行。12名患者将接受8次30分钟的tDCS治疗(每周两次,为期四周)。在干预前后,将使用吞咽困难风险评估方案(PARD)、进食评估工具(EAT-10)和吞咽障碍生活质量方案(sval - qol)评估吞咽功能。该方案为tDCS治疗吞咽困难的临床可行性提供了初步的见解,并有助于该领域未来临床试验的发展。
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引用次数: 0
The progressive power program: An exercise intervention to improve health outcomes in adults with overweight and obesity 渐进式力量计划:一项改善超重和肥胖成人健康结果的运动干预
IF 1.9 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2025-12-14 DOI: 10.1016/j.mex.2025.103766
V. Bilro , A. Duarte Martins , T. Sobral , J.A. Parraca , M.I. Varela-Silva , N. Batalha
The present study outlines the progressive power program (PPP), a structured exercise protocol developed for adults with overweight and obesity. The PPP integrates high-intensity interval training (HIIT), high-intensity functional training (HIFT), and moderate-intensity continuous training (MICT) within a progressive 12-week framework. Participants complete three 50-minute sessions per week, delivered either face-to-face or remotely, using bodyweight exercises and self-regulated pacing guided by heart rate monitoring and perceived exertion.
The protocol is described in sufficient detail to ensure reproducibility and adaptability across diverse clinical, community, and online settings. Emphasising accessibility, safety, and participant autonomy, the PPP aims to reduce barriers related to equipment, supervision, and location. Standardised procedures for anthropometric, functional, and behavioural assessments reinforce methodological rigour.
By combining evidence-based exercise modalities with scalable delivery strategies, the PPP offers a resource-efficient and adaptable approach to promoting physical activity and supporting weight management. Its methodological design aligns with public health priorities by addressing physical inactivity, reducing sedentary behaviour, and improving health outcomes in at-risk populations.
  • Designed a progressive 12-week exercise protocol incorporating HIIT, HIFT, and MICT modalities.
  • Assessed feasibility and reach by comparing face-to-face and remote delivery formats.
  • Evaluated physical, functional, and behavioural outcomes before and after the intervention.
目前的研究概述了渐进式力量计划(PPP),这是一种为超重和肥胖的成年人开发的结构化运动方案。PPP将高强度间歇训练(HIIT)、高强度功能性训练(HIFT)和中强度连续训练(MICT)整合在一个渐进式的12周框架内。参与者每周完成三次50分钟的训练,面对面或远程授课,通过体重练习和心率监测和感知运动引导的自我调节步调。该方案有足够详细的描述,以确保在不同的临床、社区和在线环境下的可重复性和适应性。PPP强调可达性、安全性和参与者自主性,旨在减少与设备、监督和位置相关的障碍。人体测量学、功能和行为评估的标准化程序加强了方法的严谨性。通过将基于证据的锻炼模式与可扩展的交付策略相结合,PPP提供了一种资源高效且适应性强的方法来促进身体活动和支持体重管理。其方法设计符合公共卫生重点,解决缺乏身体活动问题,减少久坐行为,改善高危人群的健康状况。•设计了一个渐进式的12周运动方案,包括HIIT、HIFT和MICT模式。•通过比较面对面和远程交付形式评估可行性和覆盖范围。•评估干预前后的身体、功能和行为结果。
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引用次数: 0
Innovative parallel grasshopper optimization algorithm for reliability optimization 创新的并行蚱蜢优化算法用于可靠性优化
IF 1.9 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2025-12-14 DOI: 10.1016/j.mex.2025.103759
Dipti Singh, Neha Chand
This study introduces a novel Parallel Grasshopper Optimization Algorithm (p-GOA), specifically designed to address reliability optimization problems. Although several hybrid algorithms exist in this field, the proposed p-GOA distinctly differs through its parallel cooperative strategy. Unlike sequential methods that apply techniques one after another, p-GOA simultaneously divides the population into two groups operating in parallel: one group employs a migration strategy (SOMA) for broad global exploration of the search space, while the other utilizes a mutation operator (NUMO) for focused local refinement of solutions. This dual-strategy parallel operation creates achieving a stronger balance between global exploration and local refinement, while a smart penalty-free method naturally steers the search toward workable solutions. When tested on four well-known reliability problems, the results demonstrate that our method consistently finds more reliable systems and converges faster than existing approaches, demonstrating its effectiveness in handling real-world engineering constraints.
● This study introduces a Parallel Grasshopper Optimization Algorithm (p-GOA) that integrates GOA, SOMA, and a Non-Uniform Mutation Operator (NUMO). It employs mutation, migration, and a parallel approach to efficiently explore both feasible and near-feasible regions without relying on penalty functions.
● The p-GOA dividing the population into two parallel groups—one updated using SOMA-based migration and the other using NUMO-based mutation. This dual-strategy, simultaneous processing not only accelerates convergence but also strengthens the balance between global search and local optimization.
● Specifically targets reliability optimization problems, particularly redundancy allocation issues where components must meet specific reliability and resource consumption (cost, weight, volume) constraints.
本文介绍了一种新的并行蚱蜢优化算法(p-GOA),专门用于解决可靠性优化问题。虽然该领域存在多种混合算法,但所提出的p-GOA通过其并行合作策略具有明显的不同之处。与顺序方法不同,p-GOA同时将种群分为并行操作的两组:一组使用迁移策略(SOMA)对搜索空间进行广泛的全局探索,而另一组使用突变算子(NUMO)对解决方案进行集中的局部优化。这种双策略并行操作在全局勘探和局部优化之间实现了更强的平衡,而一种智能的无惩罚方法自然地引导了对可行解决方案的搜索。当对四个众所周知的可靠性问题进行测试时,结果表明,我们的方法始终能够找到更可靠的系统,并且比现有方法收敛得更快,证明了它在处理实际工程约束方面的有效性。●本研究引入了一种并行蚱蜢优化算法(p-GOA),该算法集成了GOA、SOMA和非均匀变异算子(NUMO)。它采用突变、迁移和并行方法来有效地探索可行和近可行区域,而不依赖于惩罚函数。●p-GOA将种群划分为两个平行组,一个使用基于somo的迁移更新,另一个使用基于numo的突变更新。这种双重策略的同时处理不仅加快了收敛速度,而且加强了全局搜索和局部优化之间的平衡。●专门针对可靠性优化问题,特别是冗余分配问题,其中组件必须满足特定的可靠性和资源消耗(成本,重量,体积)的限制。
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引用次数: 0
The Rapid Initial Community Builder (RICB) V1.1 for LANDIS-II 用于LANDIS-II的快速初始社区构建器(RICB) V1.1
IF 1.9 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2025-12-13 DOI: 10.1016/j.mex.2025.103765
Steven A Flanagan , Zachary J. Robbins , Mac A. Callaham Jr , J. Kevin Hiers , Brian R. Miranda , Joseph J. O’Brien , Robert M. Scheller , E. Louise Loudermilk
Forest succession, or ecosystem process models, can aid in many land management decisions as they inherently incorporate ecological processes to predict how disturbances impact the resilience of the forest and its potential future structure. The landscape class of ecosystem process models are often ideal for management goals as they simulate individual tree species interactions through time at the landscape scale and offer a robust assortment of disturbance extensions. However, broad implementation and adoption are often limited as users must rebuild the landscape models for every new site of interest. Creation of the initial forest communities that all model simulations depend on, can be particularly time consuming. To address this issue, we created the Rapid Initial Community Builder (RICB) that:
  • Starts with high resolution CONtinental United States (CONUS) forest coverage and type data.
  • Makes modifications to the data for use in the landscape class ecosystem process model LANDIS-II.
  • Packages everything in an executable file that eliminates coding language or version barriers.
Thus, greatly reducing the initialization time often associated with the intensive data assimilation techniques commonly used to generate initial communities.
森林演替或生态系统过程模型可以帮助许多土地管理决策,因为它们本质上包含生态过程,以预测干扰如何影响森林的恢复能力及其潜在的未来结构。景观类生态系统过程模型通常是理想的管理目标,因为它们模拟了景观尺度上单个树种随时间的相互作用,并提供了各种各样的干扰扩展。然而,广泛的实施和采用往往受到限制,因为用户必须为每个感兴趣的新站点重新构建景观模型。所有模型模拟所依赖的原始森林群落的创建可能特别耗时。为了解决这个问题,我们创建了快速初始社区构建器(RICB),它:•从高分辨率美国大陆(CONUS)森林覆盖率和类型数据开始。•对用于景观级生态系统过程模型LANDIS-II的数据进行修改。•将所有内容打包到可执行文件中,从而消除编码语言或版本障碍。因此,大大减少初始化时间通常与用于生成初始社区的密集数据同化技术相关。
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引用次数: 0
Managing missing MUKEYs in the QSWAT+ SSURGO database 管理QSWAT+ SSURGO数据库中缺失的mukey
IF 1.9 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2025-12-13 DOI: 10.1016/j.mex.2025.103764
Mahesh R. Tapas , Asmita Murumkar , Chris George , Brian Brandt , Jay Martin
The Soil and Water Assessment Tool Plus (SWAT+) is a widely used hydrological model for simulating water flow, sediment transport, and the impacts of land management on watersheds. It relies on soil data to represent how soil properties influence water movement, nutrient cycling, and crop growth within a watershed. The Soil Survey Geographic (SSURGO) database provides detailed, high-resolution soil information essential for such modeling. However, a common challenge arises when missing (Map Unit Keys) in the SWAT+ SSURGO database prevents the creation of Hydrological Response Units (HRUs), effectively halting model development. This study presents a method using QGIS to resolve missing MUKEY issues. Specifically, we demonstrate the use of QGIS's Eliminate Selected Polygons tool with the "Largest Common Boundary" option to merge missing MUKEY polygons, maintaining spatial coherence and enabling HRU generation. This approach simplifies the workflow, reduces manual effort, and improves model readiness and accuracy.
  • The study presents a method for resolving missing MUKEYs in the QSWAT+ SSURGO database, facilitating further development of SWAT+ and minimizing manual errors.
  • QSWAT+ version 3.0.2 improves error reporting by listing missing MUKEYs in the QGIS log, simplifying troubleshooting.
  • Using QGIS’s Eliminate Selected Polygons tool with the "Largest Common Boundary" option preserves spatial integrity while addressing missing data gaps.
SWAT+是一种广泛使用的水文模型,用于模拟水流、泥沙运移以及土地管理对流域的影响。它依靠土壤数据来表示土壤特性如何影响流域内的水分运动、养分循环和作物生长。土壤调查地理(SSURGO)数据库为这种建模提供了详细的、高分辨率的土壤信息。然而,SWAT+ SSURGO数据库中缺少地图单元键(Map Unit Keys)会阻碍水文响应单元(hru)的创建,从而有效地阻止了模型的开发。本研究提出了一种使用QGIS来解决缺失的MUKEY问题的方法。具体来说,我们演示了使用QGIS的“消除选定多边形”工具和“最大公共边界”选项来合并缺失的MUKEY多边形,保持空间一致性并启用HRU生成。这种方法简化了工作流程,减少了手工工作,并提高了模型的准备程度和准确性。•本研究提出了一种解决QSWAT+ SSURGO数据库中缺失mukey的方法,促进了SWAT+的进一步发展,并最大限度地减少了人工错误。•QSWAT+ 3.0.2版本通过在QGIS日志中列出丢失的mukey来改进错误报告,简化故障排除。•使用QGIS的消除选定多边形工具与“最大公共边界”选项保持空间完整性,同时解决缺失的数据差距。
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引用次数: 0
A protocol for assessing smallholder farmers’ climate resilience: A guidance for researchers to construct a robust multidimensional domain 评估小农气候适应能力的协议:指导研究人员构建稳健的多维域
IF 1.9 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2025-12-13 DOI: 10.1016/j.mex.2025.103763
Imade Yoga Prasada , Jangkung Handoyo Mulyo , Hani Perwitasari , Agus Dwi Nugroho
In recent years, the theoretical frameworks on climate resilience of smallholder farmers have continued to develop. This has encouraged the emergence of a variety of domains, indicators, and items. Meanwhile, inappropriate construct domains, indicators, and items can lead to biased research findings. Therefore, developing a robust construct domain, indicators, and items requires a clear, easily understood, and statistically accountable protocol. This protocol emphasizes the formation of a framework for conducting a statistical approach to assess smallholder farmers’ climate resilience.
近年来,关于小农气候适应能力的理论框架不断发展。这鼓励了各种领域、指标和项目的出现。同时,不恰当的构建域、指标和项目也会导致研究结果的偏差。因此,开发一个健壮的构造域、指示器和项目需要一个清晰、易于理解和统计上负责任的协议。该议定书强调形成一个框架,以便采用统计方法评估小农的气候适应能力。
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引用次数: 0
Existence, Stability, and Control of Glucose-Insulin Dynamics via Caputo-Fabrizio Fractal-Fractional Operators 基于Caputo-Fabrizio分形-分数算子的葡萄糖-胰岛素动力学的存在、稳定性和控制
IF 1.9 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2025-12-12 DOI: 10.1016/j.mex.2025.103757
Sayed Saber , Abdullah A. Alahmari
<div><div>This study presents a novel numerical framework for simulating glucose-insulin regulatory dynamics using the Caputo-Fabrizio (CF) fractal-fractional operator with both constant and variable fractional orders. The model incorporates an exponential decay kernel to capture memory and hereditary effects in metabolic regulation. A Newton interpolation-based numerical scheme is developed to approximate the CF-FF derivatives, ensuring computational stability and accuracy. For the variable-order formulation, the fractional order <span><math><mrow><mi>β</mi><mo>(</mo><mi>t</mi><mo>)</mo></mrow></math></span> dynamically evolves with time, reflecting physiological variability typically observed during intravenous glucose tolerance tests (IVGTT). Numerical experiments reproduce physiologically realistic glucose-insulin oscillations and demonstrate how feedback control stabilizes chaotic metabolic behavior. The results are based entirely on simulation evidence calibrated within clinically reported parameter ranges, providing conceptual validation rather than direct patient-data comparison. The proposed approach bridges mathematical fractional calculus with biomedical applications, offering new insights for personalized diabetes management and adaptive glucose control strategies.<ul><li><span>•</span><span><div>Fractal-fractional model formulation capturing glucose-insulin memory and adaptation</div></span></li><li><span>•</span><span><div>Stable numerical scheme using Newton interpolation for accurate fractional integration</div></span></li><li><span>•</span><span><div>Linear feedback control applied to regulate chaotic glucose-insulin dynamics</div></span></li><li><span>•</span><span><div>Numerical Methodology for glucose-insulin dynamics. Our investigation of the fractal-fractional glucose-insulin system employs the following analytical framework:</div></span></li><li><span>•</span><span><div>Model Development: We formulate a fractal-fractional-order extension of the minimal glucose insulin model, incorporating an exponential decay type kernel to capture the system's memory effects and anomalous diffusion characteristics inherent in metabolic processes. The model accounts for both insulin-dependent and independent glucose utilization dynamics.</div></span></li><li><span>•</span><span><div>Computational Implementation: We develop a novel numerical solver based on Newton's interpolation polynomials, implementing the Atangana-Seda fractal-fractional derivative formulation. This method provides an efficient computational framework for solving the coupled nonlinear fractional differential equations while maintaining numerical stability across different fractional orders.</div></span></li><li><span>•</span><span><div>The purpose of this section is to define a mathematical model to study the dynamic behavior of glucose-insulin physiology.</div></span></li><li><span>•</span><span><div>With the Adams-Bashforth-Moulton numerical scheme, we compute the Lyap
本研究提出了一种新的数值框架,用于模拟葡萄糖-胰岛素调节动力学,使用Caputo-Fabrizio (CF)分形-分数算子具有恒定和可变分数阶。该模型包含一个指数衰减核,以捕获代谢调节中的记忆和遗传效应。提出了一种基于牛顿插值的近似CF-FF导数的数值格式,保证了计算的稳定性和准确性。对于变阶公式,分数阶β(t)随时间动态变化,反映了静脉内葡萄糖耐量试验(IVGTT)中观察到的典型生理变异。数值实验再现了生理上真实的葡萄糖-胰岛素振荡,并演示了反馈控制如何稳定混乱的代谢行为。结果完全基于在临床报告参数范围内校准的模拟证据,提供概念验证,而不是直接的患者数据比较。所提出的方法将数学分数微积分与生物医学应用相结合,为个性化糖尿病管理和自适应血糖控制策略提供了新的见解。•分形-分数模型公式捕获葡萄糖-胰岛素记忆和适应•稳定的数值方案使用牛顿插值精确分数积分•线性反馈控制应用于调节混乱葡萄糖-胰岛素动力学•数值方法葡萄糖-胰岛素动力学。我们对分形-分数型葡萄糖-胰岛素系统的研究采用以下分析框架:•模型开发:我们制定了最小葡萄糖胰岛素模型的分形-分数阶扩展,结合指数衰减型核来捕获系统的记忆效应和代谢过程中固有的异常扩散特征。该模型考虑了胰岛素依赖型和独立型葡萄糖利用动态。•计算实现:我们开发了一种基于牛顿插值多项式的新型数值求解器,实现了Atangana-Seda分形-分数阶导数公式。该方法为求解耦合非线性分数阶微分方程提供了一个有效的计算框架,同时保持了不同分数阶的数值稳定性。•本节的目的是定义一个数学模型来研究葡萄糖-胰岛素生理学的动态行为。•利用Adams-Bashforth-Moulton数值格式,计算了系统的Lyapunov指数,这对研究耗散是有用的。•采用广义数值方法,利用Atangana-Seda的时间分形分数阶导数模拟了系统的解。
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引用次数: 0
A cross-sectional study on hypertension and diabetes care cascade and prevalence of noncommunicable diseases risk factors in Tamil Nadu: rationale and methods 泰米尔纳德邦高血压和糖尿病护理级联和非传染性疾病危险因素流行的横断面研究:理由和方法
IF 1.9 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2025-12-11 DOI: 10.1016/j.mex.2025.103753
Archana Ramalingam , Joshua Chadwick , Mosoniro Kriina , Manjula Devi Neelavanan , Anusuya Govindan , Devendhiran R , Vettrichelvan Venkatasamy , Emily Devasagayam , Surya Joseph , Swathy Madhusoodanan , Bhoopathy Kangusamy , Sabarinathan Ramaswamy , Elavarasu Govindasamy , Kalaimani I , Ashok Kumar Paparaju , Chokkalingam D , Dinesh Kumar , Daniel Rajasekar , Augustine Duraisamy , Sudharshini Subramaniam , Manoj Murekhar
Tamil Nadu conducted the first round of WHO STEPS survey in 2020 to assess non-communicable disease (NCD) risk factors. In 2021, subsequently the state launched the Makkalai Thedi Maruthuvam (MTM) initiative to deliver home-based care for individuals with NCDs. To evaluate the effectiveness of the program, we designed a population-based survey in 2023–2024 using electoral booth sampling as a primary sampling unit to assess control rates of hypertension and diabetes among individuals aged 18–69 years using the same WHO STEPS approach. Secondary objective was to estimate the prevalence of behavioural and biological NCD risk factors. A multistage cluster sampling method was used across the Tamil Nadu. A total of 8880 participants were selected from 148 clusters. One eligible adult per household was selected using the KISH method. Data were collected through interviews such as sociodemographic, anthropometric and biological parameters. This survey is the first in Tamil Nadu to use updated electoral data as a sampling frame to estimate the care cascade of the hypertension and diabetes. Although limited by its cross-sectional design and lack of biochemical markers test like HbA1c and cholesterol, the survey offers a practical and scalable model for NCD surveillance in India.
  • This study used the updated electoral booth data as primary sampling units in the absence of recent census data (India) to ensure the population representativeness.
  • Comprehensive assessment of hypertension and diabetes care cascade including prevalence, awareness, treatment and control rates among the individual aged 18–69 years.
  • Designed to evaluate the impact of Makkalai Thedi Maruthuvam (MTM) scheme and support to evidence based NCD intervention in Tamil Nadu.
泰米尔纳德邦于2020年开展了第一轮世卫组织STEPS调查,以评估非传染性疾病的风险因素。随后,该州于2021年启动了Makkalai Thedi Maruthuvam (MTM)倡议,为非传染性疾病患者提供家庭护理。为了评估该计划的有效性,我们设计了一项基于人群的调查,在2023-2024年使用投票站抽样作为主要抽样单位,使用相同的WHO STEPS方法评估18-69岁人群中高血压和糖尿病的控制率。次要目的是估计行为和生物非传染性疾病危险因素的流行程度。在整个泰米尔纳德邦采用了多阶段整群抽样方法。共从148个分组中选出8880名参与者。采用KISH方法,每户选择一名符合条件的成年人。通过访谈收集社会人口学、人体测量学和生物学参数等数据。这项调查是泰米尔纳德邦首次使用更新的选举数据作为抽样框架来估计高血压和糖尿病的护理级联。尽管该调查受限于其横断面设计和缺乏HbA1c和胆固醇等生化标志物测试,但它为印度的非传染性疾病监测提供了一个实用且可扩展的模型。•本研究在缺乏最近的人口普查数据(印度)的情况下,使用更新的投票站数据作为主要抽样单位,以确保人口代表性。•全面评估高血压和糖尿病护理级联,包括18-69岁个体的患病率、意识、治疗和控制率。•旨在评估Makkalai Thedi Maruthuvam (MTM)计划的影响和对泰米尔纳德邦基于证据的非传染性疾病干预的支持。
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