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Preparation of nano zinc borate and investigation of flame-retardancy of ternary combination nano zinc borate/red phosphorus/expandable graphite on HDPE 纳米硼酸锌的制备及纳米硼酸锌/红磷/可膨胀石墨三元组合在高密度聚乙烯上的阻燃性能研究
Pub Date : 2024-01-25 DOI: 10.31276/vjst.66(1).56-61
Thi Hanh Nguyen, Thi Nhung Hac, Van Toan Hoang, Nhat Thuy Giang Le, Mai Ha Hoang, Van Tuyen Nguyen
Nano zinc borates were successfully synthesised from aqueous solutions of zinc sulfate, boric acid, and sodium hydroxide via the precipitation method. The effects of pH, temperature, and surfactants on the structure and morphologies of nano zinc borates were investigated. The nano zinc borates obtained at the pH of 7 to 8 were well-crystallised monophase Zn[B3O4(OH)3]. The morphologies of nano zinc borates were highly impacted by the reaction temperature and the surfactants. At the range of temperatures from 70 to 80oC, the nano zinc borates were nanoplates of 40-50 nm in thickness. The nano zinc borates grew out of the surface to form nanorods at 90oC and nanowhiskers at 100oC. The nano zinc borates modified with surfactants tended to form larger and thinner plate-like nanoparticles. In the presence of Tween 80, petal-like nano zinc borates were achieved. The petal-like nano zinc borates showed good flame retardant synergistic effects with red phosphorus and expandable graphite on high-density polyethylene matrix. Additionally, the nano zinc borates nanopetals significantly improved the mechanical properties of red phosphorus/expandable graphite/high-density polyethylene composites.
通过沉淀法从硫酸锌、硼酸和氢氧化钠的水溶液中成功合成了纳米硼酸锌。研究了 pH 值、温度和表面活性剂对纳米硼酸锌结构和形态的影响。在 pH 值为 7 至 8 时得到的纳米硼酸锌为结晶良好的单相 Zn[B3O4(OH)3]。纳米硼酸锌的形态受反应温度和表面活性剂的影响很大。在 70 至 80 摄氏度的温度范围内,纳米硼酸锌为厚度为 40 至 50 纳米的纳米板。在 90 摄氏度时,纳米硼酸锌从表面长出形成纳米棒,在 100 摄氏度时形成纳米须。用表面活性剂修饰的纳米硼酸锌往往会形成更大更薄的板状纳米颗粒。在吐温 80 的存在下,纳米硼酸锌形成了花瓣状。花瓣状纳米硼酸锌与红磷和可膨胀石墨在高密度聚乙烯基体上显示出良好的阻燃协同效应。此外,纳米硼酸锌还能显著改善红磷/可膨胀石墨/高密度聚乙烯复合材料的机械性能。
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引用次数: 0
Development of expression vector with the Pgrac100 promoter induced by IPTG and integrated gfp+ gene into Bacillus subtilisgenome at lacA locus 开发带有 IPTG 诱导的 Pgrac100 启动子的表达载体,并将 gfp+ 基因整合到枯草芽孢杆菌基因组的 lacA 基因座上
Pub Date : 2024-01-25 DOI: 10.31276/vjst.66(1).75-80
Thi Bich Phuong Chu, D. Nguyen, Thi Phuong Trang Phan
Bacillus subtilis is a prospective gram - positive bacterium that offers an opportunity for the production of recombinant proteins in the pharmaceutical, agricultural, industrial, and food industries.The goal of this study was to develop an integrative inducible expression system by incorporating the Pgrac100 promoter into the lacA locus of the B. subtilis genome. The results showed that the Pgrac100 promoter was able to strictly control the expression of the target protein, with induction factors of 3.3, 7.6, and 10.8 after 4 hours under induction with 0.01, 0.1, and 1 mM Isopropulβ-D-1-thiogalactopyranoside (IPTG), respectively. The duration of induction and the concentration of IPTG had significant effects on the efficacy of target protein expression. Specifically, when induced with 0.1 mM IPTG after 4 hours, there was a significant rise in GFP expression, accounting for 13% of the total cellular protein. Our new vector system provided more options for the production of recombinant proteins in basic research and industrial applications.
本研究的目的是通过将Pgrac100启动子整合到枯草杆菌基因组的lacA基因座中,开发一种整合诱导表达系统。结果表明,Pgrac100启动子能够严格控制目标蛋白的表达,在0.01、0.1和1 mM异丙β-D-1-硫代半乳糖苷(IPTG)诱导下,4小时后的诱导因子分别为3.3、7.6和10.8。诱导时间的长短和 IPTG 的浓度对目标蛋白的表达效果有显著影响。具体来说,用 0.1 mM IPTG 诱导 4 小时后,GFP 的表达量显著上升,占细胞蛋白总量的 13%。我们的新载体系统为基础研究和工业应用中重组蛋白的生产提供了更多选择。
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引用次数: 0
Chemical components and antimicrobial activity of essential oil from leaf of Aristolochia balansae Franch. 马兜铃叶精油的化学成分和抗菌活性
Pub Date : 2024-01-25 DOI: 10.31276/vjst.66(1).14-18
Dam Ngoc Anh Luu, Van Huong Bui, Van Truong Do, Thi Kieu Oanh Nguyen
Aristolochia balansae Franch. belonging to Aristolochiasubgenus Siphisia (Aristolochiaceae) is rarely distributed in Northern Vietnam. This study is the first time to determine the chemical composition and antimicrobial activity from essential oils of leaves collected in Ba Thuoc district, Thanh Hoa province in November 2021. The essential oils from the leaves of A. balansae were obtained by hydrodistillation using Clevenger-type apparatus and analysed by gas chromatography coupled with mass spectrometry. The yield of the essential oil was 0.15% of fresh weight, the essential oil is light yellow, lighter than water. Sixty-three components were identified, which present 78.58% of the total composition of the leaf’s essential oil. The main components were sesquiterpenes and oxygenated sesquiterpenes. The constituents occurring in higher amounts in the essential oil were γ-Eudesmol (6.98% of the total composition of the leaf’s essential oil), α-Humulene (6.22%), β-Selinene (4.5%), Eudesma-4(14),7(11)-diene (3.53%), α-trans-Bergamotene (3.27%), and Limonene (3.02%). This essential oil showed weak antimicrobial activities to most of the tested microbial strains in a concentration of 10%.
属于马兜铃科(Aristolochiasubgenus Siphisia)的马兜铃属植物马兜铃(Aristolochia)balansae Franch.很少分布在越南北部。本研究首次测定了 2021 年 11 月在清化省 Ba Thuoc 县采集的马兜铃叶精油的化学成分和抗菌活性。研究人员使用 Clevenger 型仪器,通过水蒸馏法从芭蕉叶中提取精油,并采用气相色谱-质谱法进行分析。精油的产量为鲜重的 0.15%,精油呈淡黄色,比水轻。共鉴定出 63 种成分,占叶片精油总成分的 78.58%。主要成分是倍半萜和含氧倍半萜。精油中含量较高的成分有:γ-桉叶油醇(占叶子精油总成分的 6.98%)、α-胡麻烯(6.22%)、β-硒烯(4.5%)、桉叶-4(14),7(11)-二烯(3.53%)、α-反式佛手柑烯(3.27%)和柠檬烯(3.02%)。在 10% 的浓度下,这种精油对大多数受测微生物菌株显示出微弱的抗菌活性。
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引用次数: 0
Accumulation of mercury in muscle of orange-spotted spinefoot(Siganus guttatus Bloch, 1787) by age and season in the coastal Quang Binh 广平沿海桔斑棘脚鹦鹉(Siganus guttatus Bloch, 1787)肌肉中按年龄和季节划分的汞积累情况
Pub Date : 2024-01-25 DOI: 10.31276/vjst.66(1).36-41
Van Thiep Vo, Thi Thu Phuong Le, Thi Huong Binh Nguyen
Orange-spotted spinefoot (Siganus guttatus) is not only a fish with high economic value, rich in nutrients, but also popular with people for consumption. This research was carried out from November 2021 to May 2022, in the coastal and estuaries of Quang Binh province. A total of 60 samples of orange-spotted spinefoot were collected by age group, wet season, and dry season to analyse the accumulation of mercury (Hg) in their muscles. The Hg concentration was analysed by cold vapour atomic absorption spectroscopy. Research results showed a strong correlation between the length and weight of fish both in the wet and dry seasons. The age group has a strong influence on the accumulation of Hg in their muscles, the older fish group has a higher aggregation of Hg than the younger fish group. Although the average value of Hg concentration in the muscle of orange-spotted spinefoot in the dry season is higher than in the wet season, analysis results of “Tukey’s HSD test” showed that there was no significant difference.
橙斑脊鳍鱼(Siganus guttatus)不仅经济价值高、营养丰富,而且深受人们的喜爱。这项研究于 2021 年 11 月至 2022 年 5 月在广平省沿海和河口进行。研究人员按年龄组、雨季和旱季收集了 60 份橙斑脊鳍鱼样本,分析其肌肉中汞的积累情况。汞浓度通过冷蒸气原子吸收光谱进行分析。研究结果表明,在雨季和旱季,鱼的体长和体重之间都有很强的相关性。鱼的年龄组对其肌肉中汞的积累有很大影响,年龄较大的鱼类比年龄较小的鱼类体内汞的聚集度更高。虽然旱季橙斑脊鳍鱼肌肉中汞浓度的平均值高于雨季,但 "Tukey's HSD 检验 "的分析结果表明两者没有显著差异。
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引用次数: 0
Optical properties of Eu3+ - doped Sr2TiO4 phosphor powder synthesised by solid-phase reaction method 固相反应法合成的 Eu3+ - 掺杂 Sr2TiO4 荧光粉的光学特性
Pub Date : 2024-01-25 DOI: 10.31276/vjst.66(1).62-67
V. Chu, Thi Anh Xuan Chu, Thi Hue Lo, Minh Quy Bui, Thi Tam Khieu, Phuong Thao Nguyen, Kim Dan Ho, Tien Ha Le
Fluorescent powder Sr2TiO4 doped with Eu3+ ions was synthesised by the solid-phase reaction method with a sintering temperature of 1200oC in the air with a 1-6% doping concentration. The resulting material has a perovskite structure of I4/mmm space group, and the Eu3+ ion doping concentration does not change the material’s structure. This characteristic space group of the material was also investigated through the Raman scattering spectrum with characteristic peaks at positions 145, 240, 448, and 699 cm-1 corresponding to vibrational modes with 2A1g + 2Egcharacteristic states of Sr2TiO4 material. The results showed that the material absorbs strongly in the ultraviolet and blue light regions with characteristic peaks of the Sr2TiO4 matrix and Eu3+ ions to emit strongly in the red light region with characteristic emission peaks of Eu3+ ions in the background network when moving from the excited state 5D0 to state 7Fj (j is a positive integer number). Fluorescence quenching was also observed at a doping concentration of 4% Eu3+ ions. The fabricated material is suitable for coating applications on nUV-LED LED chips.
采用固相反应法合成了掺杂 Eu3+ 离子的荧光粉 Sr2TiO4,烧结温度为 1200 摄氏度,掺杂浓度为 1-6%。得到的材料具有 I4/mmm 空间群的包晶结构,Eu3+ 离子的掺杂浓度不会改变材料的结构。拉曼散射光谱在 145、240、448 和 699 cm-1 位置出现了特征峰,对应于 Sr2TiO4 材料的 2A1g + 2Eg 特征态振动模式,从而研究了材料的这一特征空间群。结果表明,当材料从激发态 5D0 进入状态 7Fj(j 为正整数)时,在紫外光和蓝光区域会强烈吸收,出现 Sr2TiO4 基体和 Eu3+ 离子的特征峰,在红光区域会强烈发射,出现背景网络中 Eu3+ 离子的特征发射峰。在 Eu3+ 离子掺杂浓度为 4% 时,也观察到了荧光淬灭现象。制备的材料适用于 nUV-LED LED 芯片的涂层应用。
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引用次数: 0
Research on production and testing of antifungal activity Phytophthora spp. causing fruit rot and Colletotrichum spp. causing anthracnose of silver nanoparticles, chitosan and turmeric resin bioproducts 纳米银颗粒、壳聚糖和姜黄树脂生物产品的生产和抗真菌活性测试研究,这些产品可引起果实腐烂病的噬菌目和引起炭疽病的 Colletotrichum spp.
Pub Date : 2024-01-25 DOI: 10.31276/vjst.66(1).42-49
Duc Danh Cao, The Tam Le, Van Binh Thai, Thi Ngan Tran, Dang Quang Le, D. Ho, Cao Cuong Nguyen, Thi Ha Nguyen, Thi Thu Hiep Le, Phuong Chi Tran, Thi Ngan Duong
In this paper, the research team made samples of bio-products (BN) of turmeric resin combined with silver nanoparticles and chitosan and investigated the factors affecting the production of BN preparations. Specifically, the results of research on the production of BN preparations including ingredients, additives, mixing ratios, and technological parameters have been calculated and tested to obtain nano-preparations with the highest durability and dispersion. The experimental results obtained the optimal set of parameters for production at a pilot scale of 5 litres/batch are the ratio of active ingredients/additives =3/1, the optimal temperature for the mixing process is 40-45oC, the stirring speed is 500 rpm, and the time is 60 minutes. From here, we have successfully fabricated 18 samples of BN1-BN18 preparations with colours ranging from light yellow to dark yellow. Antifungal activity was tested against Colletotrichum spp. causing anthracnose disease and fruit rot disease caused by Phytophthora spp., the results showed that BN1-BN18 products exhibited good antifungal activity, and antifungal activity increased gradually when the content of turmeric oil resin increased.
在本文中,研究小组制作了姜黄树脂与纳米银颗粒和壳聚糖结合的生物产品(BN)样品,并研究了影响 BN 制剂生产的因素。具体而言,对 BN 制剂的生产研究成果,包括成分、添加剂、混合比例和技术参数进行了计算和测试,以获得具有最高耐久性和分散性的纳米制剂。实验结果表明,在 5 升/批的中试规模下,最佳生产参数设置为活性成分/添加剂的比例 =3/1,混合过程的最佳温度为 40-45oC,搅拌速度为 500 rpm,时间为 60 分钟。由此,我们成功制备出 18 种 BN1-BN18 制剂样品,颜色从浅黄色到深黄色不等。结果表明,BN1-BN18 产品具有良好的抗真菌活性,且随着姜黄油树脂含量的增加,抗真菌活性逐渐增强。
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引用次数: 0
Phase transitions of smectic-isotropic phase in liquid crystals 液晶中的各向异性共晶相的相变
Pub Date : 2024-01-15 DOI: 10.31276/vjst.66(1).01-07
Thi Phuong Thuy Nguyen, Thi Van Anh Nguyen, Van Thanh Ngo
Smectic phases formed by rod-like molecules with long axes that are parallel and also arranged in planes. The smectic-isotropic phase transition is a phase change from the liquid crystal to the liquid phase. In this work, we use a mobile 6-state Potts model to study the nature of the smectic-isotropic phase transition. Microscopic interactions between neighbouring molecules in this model are supplemented with the Lennard-Jones potential. This study applies Monte Carlo simulation with the Wang-Landau algorithm to determine the characteristics of smectic-isotropic phase transitions. It is shown clearly that the smectic phase goes to the isotropic phase and undergoes a first-order transition. The results also point out that when the temperature increases, molecules on the surface are orientationally disordered, then the molecules gradually lose their positional order. These results are in agreement with experiments that revealed the coexistence of the smectic and isotropic phasesduring the phase transition process in accordance with experimental studies.
各向异性相是指由长轴平行且呈平面排列的杆状分子形成的各向异性相。共晶-各向异性相变是从液晶到液相的相变。在这项研究中,我们使用移动 6 态波特斯模型来研究共晶-各向同性相变的性质。在该模型中,相邻分子之间的微观相互作用辅以伦纳德-琼斯势。本研究采用 Wang-Landau 算法进行蒙特卡罗模拟,以确定各向同性相变的特征。结果清楚地表明,共晶相转变为各向同性相,并经历了一阶转变。结果还指出,当温度升高时,表面的分子取向无序,然后分子逐渐失去位置秩序。这些结果与实验结果一致,实验结果表明,在相变过程中,各向同性相和各向异性相共存。
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引用次数: 0
Plant-parasitic nematodes associated with Paphiopedilum appletonianum (Gower) Rolfe 1896 与 Paphiopedilum appletonianum (Gower) Rolfe 1896 相关的植物寄生线虫
Pub Date : 2024-01-15 DOI: 10.31276/vjst.66(1).19-23
T. Le, Thi Duyen Nguyen, H. T. Nguyen, V. T. Bui, Van Sinh Nguyen, Van Tien Tran, Quang Phap Trinh
The genus Paphiopedilum Pfitzer includes many plant species that are threatened with extinction. The groups of plant-parasitic nematodes that have been published parasitising orchids show that the stem and leaf nematode group and the root nematode group are all present and cause direct damage to this orchid genus. Besides, plant-parasitic nematodes are also one of the vectors for other pests to invade and cause quality damage to commercial orchids. Therefore, this study was carried out with the goal of initially identifying the main nematode species that parasitises Paphiopedilum appletonianum (Gower) Rolfe 1896 collected in Ba Na natural forest (Da Nang) to serve for prevention of plant diseases in the conservation of this orchid species. As a result, for the first time, 12 species of plant-parasitic nematodes associated with Paphiopedilum appletonianum in Vietnam have been recorded. The study has described the two main species, Paratrichodorus minor and Helicotylenchus dihystera, that are present with high density in soil and that are present also in stems and roots, what enables the appropriate preventive measures could be undertaken during the conservation of this rareorchid species.
Paphiopedilum Pfitzer 属包括许多濒临灭绝的植物物种。已公布的寄生于兰花的植物寄生线虫群表明,茎叶线虫群和根线虫群都存在,并对该兰花属造成直接损害。此外,植物寄生线虫也是其他害虫入侵并对商品兰造成质量损害的媒介之一。因此,本研究旨在初步确定寄生于岘港巴那天然林中 Paphiopedilum appletonianum (Gower) Rolfe 1896 的主要线虫种类,以便在保护该兰科植物时预防植物病害。结果,越南首次记录了与 Paphiopedilum appletonianum 相关的 12 种植物寄生线虫。该研究描述了两种主要的线虫--Paratrichodorus minor 和 Helicotylenchus dihystera,这两种线虫在土壤中的密度很高,在茎和根中也有分布,因此可以在保护这一珍稀兰科植物的过程中采取适当的预防措施。
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引用次数: 0
Evaluation of the involvement of HSC70 gene in the growth and development of tomato 评估 HSC70 基因参与番茄生长发育的情况
Pub Date : 2024-01-15 DOI: 10.31276/vjst.66(1).29-35
Tuan Nam Vu, Quang Ha Dao, Nhat Linh Nguyen, Han Ly Luu, Hong Hanh Ha, Thi Thu Hue Huynh, Thi Thu Hien Le
Tomato is one of the high-value agricultural crops. The HSP70 gene family is thought to play an important role in plant tolerance to various environmental factors. A family member known as HSC70 is predicted to be involved in plant growth and development, however, its biological functions have not been demonstrated clearly. This study was conducted with the aim to characterise the HSC70 gene in tomato plants and evaluate its contribution to tomato growth through phenotypic analysis of plant mutants with defects in the HSC70 gene. The research results showed that nonsense mutationin the HSC70 gene caused short plant and reduced the seed germination rate and fruit set rate of tomato. However, these missense mutations did not change these phenotypes significantly. The leaf shape, leaf structure, and flowering time of tomato were not affected by the HSC70 mutations. These findings provided preliminary insights for further study on the role of the HSC70gene in the germination, elongation, and fruit setting of tomato plants.
番茄是高价值农作物之一。HSP70 基因家族被认为在植物耐受各种环境因素方面发挥着重要作用。其中一个名为 HSC70 的家族成员被认为参与了植物的生长和发育,但其生物学功能尚未得到明确证实。本研究旨在通过对 HSC70 基因缺陷突变体的表型分析,确定番茄植株中 HSC70 基因的特征,并评估其对番茄生长的贡献。研究结果表明,HSC70 基因的无义突变会导致番茄植株矮小,降低种子发芽率和坐果率。然而,这些错义突变并没有显著改变这些表型。番茄的叶形、叶片结构和开花时间也没有受到HSC70基因突变的影响。这些发现为进一步研究 HSC70 基因在番茄植株的发芽、伸长和坐果过程中的作用提供了初步启示。
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引用次数: 0
Factors affecting adherence to ARV of HIV-infected adolescents at the Outpatient Clinic, Vietnam National Children’s Hospital in 2022-2023 影响 2022-2023 年越南国家儿童医院门诊感染艾滋病毒的青少年坚持使用抗逆转录病毒药物的因素
Pub Date : 2023-12-25 DOI: 10.31276/vjst.65(12).28-33
Thi Dung Trinh, Thien Hai Do, Thi Van Nguyen, Thi Bich Ho, Thi Ngoc Tran, LeMai Nguyen, Thi Lien Tinh Phung, Thanh Dong Nguyen, Xuan Binh Vuong, Thi Bao Ngoc Nguyen, Thi Thu Hang Nguyen, Thi Hong Nguyen, Thanh Thuy Dang, Thi Dung Nguyen, Thi Hang Le, Thi Xuyen Tran
Objectives: (1) Describe the characteristics of pediatric patients and treatment adherence of HIV-infected adolescents at the Outpatient Clinic of the Vietnam National Children’s Hospital in 2022-2023; (2) Analysis of some factors affecting adherence to ARV treatment of HIV-infected adolescents. Research subject and method: The study was carried out on 222 HIV-infected adolescents who met the research criteria to visit the Outpatient Clinic of the Vietnam National Children’s Hospital in 2022-2023 by cross-sectional descriptive research method. Results: The treatment adherence rate of adolescents accounted for 84.2%. Some factors affecting adherence to ARV treatment of HIV-infected adolescents include: children who attended counselling classes at the clinic were 2.32 times more compliant than children who did not (p<0.05); educated children with the same level of education as the age group of ARVs are 3.46 times higher than the age group with no education equivalent to the age group (CI95% 1.39-8.57, X2=7.87, p=0); children whose HIV status was fully disclosed at 10-12 years of age had higher adherence rates than children whose HIV status was revealed at other time points, this result is statistically significant (X2=10.5, p<0.05); the primary caregivers participating in the study who knew well about HIV/AIDS helped children to adhere to ARV treatment higher than those whose primary caregivers lacked knowledge about HIV/AIDS, this result is statistically significant (X2=6.5, p<0.05). Conclusion: The ARV adherence rate of adolescents accounts for 84.2%, this rate is not high. A number of factors increase the rate of treatment adherence: children become infected at 10-12 years of age, children attend HIV counselling classes, educational attainment equivalent to age, caregivers' knowledge of HIV main squirrel.
目的:(1)描述2022-2023年越南国家儿童医院门诊部儿科患者的特点和感染艾滋病病毒的青少年坚持治疗的情况;(2)分析影响感染艾滋病病毒的青少年坚持抗逆转录病毒治疗的一些因素。研究对象和方法:研究对象为2022-2023年在越南国家儿童医院门诊就诊的222名符合研究标准的HIV感染青少年,研究方法为横断面描述性研究。结果显示青少年的治疗依从率为84.2%。影响HIV感染青少年ARV治疗依从性的一些因素包括:在门诊参加辅导班的孩子比没有参加辅导班的孩子依从性高2.32倍(P<0.05);与ARV年龄组同等教育程度的孩子比没有同等教育程度的年龄组高3.46倍(CI95% 1.39-8.57,X2=7.87,P=0);在 10-12 岁时完全公开艾滋病病毒感染状况的儿童比在其他时间点公开艾滋病病毒感染状况的儿童的坚持率更高,这一结果具有统计学意义(X2=10.5,P<0.05);参与研究的主要照顾者对艾滋病病毒/艾滋病非常了解的,比主要照顾者缺乏艾滋病病毒/艾滋病知识的,对儿童坚持抗逆转录病毒治疗的帮助更大,这一结果具有统计学意义(X2=6.5,P<0.05)。结论青少年的抗逆转录病毒治疗依从率为 84.2%,这一比率并不高。一些因素可以提高治疗依从率:儿童在 10-12 岁时感染、儿童参加艾滋病咨询课程、受教育程度与年龄相当、照顾者对艾滋病知识的了解。
{"title":"Factors affecting adherence to ARV of HIV-infected adolescents at the Outpatient Clinic, Vietnam National Children’s Hospital in 2022-2023","authors":"Thi Dung Trinh, Thien Hai Do, Thi Van Nguyen, Thi Bich Ho, Thi Ngoc Tran, LeMai Nguyen, Thi Lien Tinh Phung, Thanh Dong Nguyen, Xuan Binh Vuong, Thi Bao Ngoc Nguyen, Thi Thu Hang Nguyen, Thi Hong Nguyen, Thanh Thuy Dang, Thi Dung Nguyen, Thi Hang Le, Thi Xuyen Tran","doi":"10.31276/vjst.65(12).28-33","DOIUrl":"https://doi.org/10.31276/vjst.65(12).28-33","url":null,"abstract":"Objectives: (1) Describe the characteristics of pediatric patients and treatment adherence of HIV-infected adolescents at the Outpatient Clinic of the Vietnam National Children’s Hospital in 2022-2023; (2) Analysis of some factors affecting adherence to ARV treatment of HIV-infected adolescents. Research subject and method: The study was carried out on 222 HIV-infected adolescents who met the research criteria to visit the Outpatient Clinic of the Vietnam National Children’s Hospital in 2022-2023 by cross-sectional descriptive research method. Results: The treatment adherence rate of adolescents accounted for 84.2%. Some factors affecting adherence to ARV treatment of HIV-infected adolescents include: children who attended counselling classes at the clinic were 2.32 times more compliant than children who did not (p<0.05); educated children with the same level of education as the age group of ARVs are 3.46 times higher than the age group with no education equivalent to the age group (CI95% 1.39-8.57, X2=7.87, p=0); children whose HIV status was fully disclosed at 10-12 years of age had higher adherence rates than children whose HIV status was revealed at other time points, this result is statistically significant (X2=10.5, p<0.05); the primary caregivers participating in the study who knew well about HIV/AIDS helped children to adhere to ARV treatment higher than those whose primary caregivers lacked knowledge about HIV/AIDS, this result is statistically significant (X2=6.5, p<0.05). Conclusion: The ARV adherence rate of adolescents accounts for 84.2%, this rate is not high. A number of factors increase the rate of treatment adherence: children become infected at 10-12 years of age, children attend HIV counselling classes, educational attainment equivalent to age, caregivers' knowledge of HIV main squirrel.","PeriodicalId":18650,"journal":{"name":"Ministry of Science and Technology, Vietnam","volume":"6 11‐12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139158537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Ministry of Science and Technology, Vietnam
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