Pub Date : 2025-03-17DOI: 10.1038/d41586-025-00717-9
Veera M. Rajagopal, Sahar Gelfman
Inherited repeat mutations in the HTT gene expand in neurons over decades before crossing a toxic threshold, revealing a long time window for therapy.
{"title":"Errors in the Huntington’s disease gene accumulate slowly and then all at once","authors":"Veera M. Rajagopal, Sahar Gelfman","doi":"10.1038/d41586-025-00717-9","DOIUrl":"https://doi.org/10.1038/d41586-025-00717-9","url":null,"abstract":"Inherited repeat mutations in the HTT gene expand in neurons over decades before crossing a toxic threshold, revealing a long time window for therapy.","PeriodicalId":18787,"journal":{"name":"Nature","volume":"61 29 1","pages":""},"PeriodicalIF":64.8,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143641122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-17DOI: 10.1038/d41586-025-00794-w
Is a revolution of standards in public life the key to tackling our intertwined environmental crises? A compelling book argues it is.
{"title":"A radical manifesto for truth","authors":"","doi":"10.1038/d41586-025-00794-w","DOIUrl":"https://doi.org/10.1038/d41586-025-00794-w","url":null,"abstract":"Is a revolution of standards in public life the key to tackling our intertwined environmental crises? A compelling book argues it is.","PeriodicalId":18787,"journal":{"name":"Nature","volume":"19 1","pages":""},"PeriodicalIF":64.8,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143635286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-14DOI: 10.1038/d41586-025-00681-4
In this era of anti-science activism, it‘s wise to take steps to protect your research and reputation in the digital realm.
{"title":"Stay safe from online hate with these five tips","authors":"","doi":"10.1038/d41586-025-00681-4","DOIUrl":"https://doi.org/10.1038/d41586-025-00681-4","url":null,"abstract":"In this era of anti-science activism, it‘s wise to take steps to protect your research and reputation in the digital realm.","PeriodicalId":18787,"journal":{"name":"Nature","volume":"24 1","pages":""},"PeriodicalIF":64.8,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143627394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-14DOI: 10.1038/d41586-025-00357-z
{"title":"A century of quantum physics.","authors":"","doi":"10.1038/d41586-025-00357-z","DOIUrl":"https://doi.org/10.1038/d41586-025-00357-z","url":null,"abstract":"","PeriodicalId":18787,"journal":{"name":"Nature","volume":" ","pages":""},"PeriodicalIF":50.5,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143634079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-14DOI: 10.1038/d41586-025-00500-w
Single-use plastics are everywhere — but two researchers are redefining the norm and championing sustainability.
{"title":"Your lab pollutes: here’s how to stop it","authors":"","doi":"10.1038/d41586-025-00500-w","DOIUrl":"https://doi.org/10.1038/d41586-025-00500-w","url":null,"abstract":"Single-use plastics are everywhere — but two researchers are redefining the norm and championing sustainability.","PeriodicalId":18787,"journal":{"name":"Nature","volume":"54 1","pages":""},"PeriodicalIF":64.8,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143618409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-14DOI: 10.1038/d41586-025-00707-x
The drop in body temperature that occurs during a torpid state is linked to molecular markers of longer life in mice.
{"title":"How extreme lethargy can promote healthy ageing","authors":"","doi":"10.1038/d41586-025-00707-x","DOIUrl":"https://doi.org/10.1038/d41586-025-00707-x","url":null,"abstract":"The drop in body temperature that occurs during a torpid state is linked to molecular markers of longer life in mice.","PeriodicalId":18787,"journal":{"name":"Nature","volume":"204 1","pages":""},"PeriodicalIF":64.8,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143627392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-14DOI: 10.1038/d41586-025-00812-x
The US government has begun slashing US$400 million in research grants at Columbia University over pro-Palestinian campus protests.
{"title":"‘My career is over’: Columbia University scientists hit hard by Trump team’s cuts","authors":"","doi":"10.1038/d41586-025-00812-x","DOIUrl":"https://doi.org/10.1038/d41586-025-00812-x","url":null,"abstract":"The US government has begun slashing US$400 million in research grants at Columbia University over pro-Palestinian campus protests.","PeriodicalId":18787,"journal":{"name":"Nature","volume":"49 1","pages":""},"PeriodicalIF":64.8,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143627393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-14DOI: 10.1038/d41586-025-00825-6
First glimpse of the colour of mammals who lived alongside dinosaurs. Plus, what anti-vaccine rhetoric in the US government will mean for the country’s health and, in a world first, a man has survived with a titanium heart for 100 days.
{"title":"Daily briefing: Jurassic mammals had dark fur","authors":"","doi":"10.1038/d41586-025-00825-6","DOIUrl":"https://doi.org/10.1038/d41586-025-00825-6","url":null,"abstract":"First glimpse of the colour of mammals who lived alongside dinosaurs. Plus, what anti-vaccine rhetoric in the US government will mean for the country’s health and, in a world first, a man has survived with a titanium heart for 100 days.","PeriodicalId":18787,"journal":{"name":"Nature","volume":"25 1","pages":""},"PeriodicalIF":64.8,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143641124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-13DOI: 10.1038/d41586-025-00757-1
In the wake of the Trump administration’s funding freezes and job cuts, some researchers are planning their next move.
{"title":"These frustrated scientists want to leave the United States – do you? Take Nature’s poll","authors":"","doi":"10.1038/d41586-025-00757-1","DOIUrl":"https://doi.org/10.1038/d41586-025-00757-1","url":null,"abstract":"In the wake of the Trump administration’s funding freezes and job cuts, some researchers are planning their next move.","PeriodicalId":18787,"journal":{"name":"Nature","volume":"4 1","pages":""},"PeriodicalIF":64.8,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143608442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-13DOI: 10.1038/d41586-025-00705-z
A well-timed atmospheric river dropped enough snow on Greenland for its ice sheet to lose 8% less mass than expected.
{"title":"Mega-storm dumps 11 billion tonnes of snow ― and builds up a melting ice sheet","authors":"","doi":"10.1038/d41586-025-00705-z","DOIUrl":"https://doi.org/10.1038/d41586-025-00705-z","url":null,"abstract":"A well-timed atmospheric river dropped enough snow on Greenland for its ice sheet to lose 8% less mass than expected.","PeriodicalId":18787,"journal":{"name":"Nature","volume":"205 1","pages":""},"PeriodicalIF":64.8,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143608440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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