One Health最新文献

{"title":"Metagenomic survey reveals Volzhskoe tick virus in <i>Hyalomma</i> ticks for the first time in western Europe, North-Eastern Spain.","authors":"Laura Carrera-Faja, Mariette Viladomat Jasso, Iris Sarmiento, Jordi Manuel Cabrera-Gumbau, Johan Espunyes, Jaime Martínez-Urtaza, Oscar Cabezón","doi":"10.1016/j.onehlt.2025.101279","DOIUrl":"10.1016/j.onehlt.2025.101279","url":null,"abstract":"<p><p>Ticks are reservoirs and vectors of several emerging arboviruses, yet their associated virome remains poorly characterized. Using meta-transcriptomic sequencing, we surveyed <i>Hyalomma marginatum</i> and <i>Rhipicephalus bursa</i> ticks collected from areas with contrasting Crimean-Congo haemorrhagic fever virus (CCHFV) seroprevalence in wild ungulates in north-eastern Spain, a region with no reported CCHF cases in humans. While CCHFV RNA was not detected, we identified Volzhskoe tick virus (VTV), a recently described member of the class <i>Bunyaviricetes</i>, first identified in Russia, in <i>H. marginatum</i> from the Ports de Tortosa i Beseit Natural Park-making its first report of VTV in Western Europe. These findings suggest a broader distribution of VTV and raise important questions about its potential interactions with CCHFV, pathogenicity and host range. Moreover, our approach underscores the value of metagenomic surveillance for improving our understanding of tick-borne virus ecology.</p>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"21 ","pages":"101279"},"PeriodicalIF":4.5,"publicationDate":"2025-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12721309/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145820548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What are we eating?. Detection of antibiotic resistance mechanisms in frozen chicken nuggets imported from Brazil","authors":"Nicolás F. Cordeiro,&nbsp;Nadia Coppola,&nbsp;Federica Ferreira,&nbsp;Rafael Vignoli,&nbsp;Inés Bado","doi":"10.1016/j.onehlt.2025.101171","DOIUrl":"10.1016/j.onehlt.2025.101171","url":null,"abstract":"<div><div>The rise of antibiotic resistance is a growing challenge, affecting humans, the environment, and animals. Under the One Health framework, this study investigated resistance mechanisms to critically important antibiotics in frozen chicken nuggets imported from Brazil.</div><div>Eighty nugget samples were cultured on selective media containing ceftriaxone, ciprofloxacin, or colistin. Isolates were identified using MALDI-TOF, and antibiotic susceptibility was assessed by disk diffusion. Eight samples were also analyzed using shotgun metagenomic sequencing processed through the SqueezeMeta pipeline.</div><div>Nineteen Enterobacterales resistant mainly to β-lactams and to a lesser extent, to quinolones and aminoglycosides, were identified. Eight <em>Pseudomonas</em> spp. were recovered, including one <em>P. fulva</em> resistant to colistin. Metagenomics revealed predominant Firmicutes, (<em>Bacillaceae</em>, <em>Lactobacillaceae</em>, and <em>Paenibacillaceae</em>) with low γ-Proteobacteria levels.</div><div>Additionally, we detected resistance genes against several antibiotics.</div><div>This study highlights the role of imported food in spreading AMR and the value of combining metagenomics with conventional microbiology to strengthen One Health surveillance.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"21 ","pages":"Article 101171"},"PeriodicalIF":4.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144892039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First molecular detection of five gastroenteritis viruses in untreated wastewater and impact of seasonal change on their distribution in Cameroon","authors":"Marie Atsama-Amougou ,&nbsp;Dowbiss Djomsi-Meta ,&nbsp;Modeste Romuald Ngamaleu ,&nbsp;Fredy Brice Nemg Simo ,&nbsp;Christophe Lontsi Saha ,&nbsp;Nadine Lamare-Boutgam ,&nbsp;Celestin Godwe ,&nbsp;Martin Maidadi-Foudi ,&nbsp;Marcel Tongo ,&nbsp;Etienne Mpabuka ,&nbsp;Charles Kouanfack ,&nbsp;Ahidjo Ayouba","doi":"10.1016/j.onehlt.2025.101110","DOIUrl":"10.1016/j.onehlt.2025.101110","url":null,"abstract":"<div><h3>Background</h3><div>Wastewater-based epidemiology has emerged as a valuable tool for surveilling food- and waterborne disease outbreaks. However, wastewater-based epidemiology remains poorly understood in sub-Saharan Africa. The current study investigated the prevalence of five human enteric viruses and the effect of seasonality on their distribution.</div></div><div><h3>Materials and methods</h3><div>A twelve-month cross-sectional study was conducted using untreated wastewater. Collected samples were concentrated by polyethylene glycol precipitation and analyzed for molecular detection of Adenovirus, Noroviruses Genotype I, Noroviruses Genotype II, Rotavirus, and Astroviruses using a commercially available Real-Time PCR Bosphore® Gastroenteritis Panel Kit.</div></div><div><h3>Results</h3><div>Overall, all target viruses were detected, with adenoviruses being the most prevalent at 88.9 % (64/72). Our results revealed the variations in the detection of all these viruses, with detection varying with the change of seasons. Although the difference in detection rates between the rainy and dry seasons did not reach statistical significance in some cases, our results reveal a consistent detection (100 %) across all sampling sites at certain seasons. Adenoviruses exhibited a peak detection period from September to November. Regarding Rotavirus and Norovirus, our findings indicate that they exhibited a peak detection during the short rainy season (March–June), with detection rates of 36.7 % (18/49) and 40.9 % (18/44), respectively.</div></div><div><h3>Conclusion</h3><div>This study provides the first report on the effect of seasonality on the distribution of enteric viruses in wastewater in Cameroon. Our results highlight the importance of considering seasonal variations when designing public health interventions and demonstrate the usefulness of wastewater-based epidemiology in environmental surveillance.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"21 ","pages":"Article 101110"},"PeriodicalIF":4.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144365357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Absence of anti-Coxiella burnetii antibodies in animal-hoarding individuals and their dogs living in a highly populated area","authors":"Danilo Alves França ,&nbsp;Igor Silva Silito ,&nbsp;Louise Bach Kmetiuk ,&nbsp;Graziela Ribeiro da Cunha ,&nbsp;Vivien Midori Morikawa ,&nbsp;Helio Langoni ,&nbsp;Marcelo Bahia Labruna ,&nbsp;Alexander Welker Biondo","doi":"10.1016/j.onehlt.2025.101169","DOIUrl":"10.1016/j.onehlt.2025.101169","url":null,"abstract":"<div><div>This study aimed to investigate the presence of anti-<em>C. burnetii</em> antibodies in animal-hoarding owners and their dogs living in Curitiba, the eighth biggest city in Brazil with 1.8 million habitants. A total of 19 animal-hoarding individuals from 21 households and their 264 dogs were sampled. Serum samples were tested by the indirect immunofluorescence assay (IFA) for IgG antibodies against <em>C. burnetii</em>. Surprisingly, no hoarding owner or dog was seropositive, significantly contrasting (<em>p</em> = 0.0001) with the previous survey in policemen and their working dogs in the same city. The absence of seropositivity herein has indicated that, despite poor living conditions, hoarding dogs may not be exposed to <em>C. burnetii</em>, highlighting the role of environmental and behavioral isolation to the Q fever epidemiology. Thus, One Health approach to <em>C. burnetii</em> should always include concomitant human-animal serosurveys, essential to establish the pathogen cycle in different environments and contributing for effective control strategies.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"21 ","pages":"Article 101169"},"PeriodicalIF":4.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144908183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Real-time malaria detection in the Amazon rainforest via drone-collected eDNA and portable qPCR","authors":"Yin Cheong Aden Ip ,&nbsp;Luca Montemartini ,&nbsp;Jia Jin Marc Chang ,&nbsp;Andrea Desiderato ,&nbsp;Nicolás D. Franco-Sierra ,&nbsp;Christian Geckeler ,&nbsp;Mailyn Adriana Gonzalez Herrera ,&nbsp;Michele Gregorini ,&nbsp;Meret Jucker ,&nbsp;Steffen Kirchgeorg ,&nbsp;Martina Lüthi ,&nbsp;Elvira Mächler ,&nbsp;Frederik Bendix Thostrup ,&nbsp;Guglielmo Murari ,&nbsp;Marina Mura ,&nbsp;Paola Pulido-Santacruz ,&nbsp;Florencia Sangermano ,&nbsp;Tobias Schindler ,&nbsp;Claus Melvad ,&nbsp;Stefano Mintchev ,&nbsp;Kristy Deiner","doi":"10.1016/j.onehlt.2025.101167","DOIUrl":"10.1016/j.onehlt.2025.101167","url":null,"abstract":"<div><div>Zoonotic malaria risk at human-wildlife-environment interfaces requires surveillance that integrates signals from reservoirs, vectors and the environment. We coupled a drone-based environmental DNA (eDNA) canopy swabbing approach with portable quantitative PCR (qPCR) to detect <em>Plasmodium</em> DNA in situ during a 24-h field exercise in the Amazon rainforest. Drone-lowered sterile swabs into the canopy, which were then extracted and subjected to a multiplex pan-<em>Plasmodium</em> assay targeting five human-infecting <em>Plasmodium</em> species (limit of detection 0.2 parasites μL⁻¹). Of 12 samples (10 canopy swabs, 2 field blanks; 13 total runs including repeats), one canopy swab amplified in duplicate (Ct = 28.7 and 29.23), while positive controls amplified as expected (Ct = 30.82 and 31.11) and all other environmental samples and blanks were negative. Passive acoustics confirmed co-occurring howler monkeys (<em>Alouatta</em> spp.), a known reservoir, whereas <em>Anopheles</em> mosquitoes were not recovered from concurrently deployed insect canopy traps. The end-to-end workflow, from drone deployment to qPCR diagnostic readout, averaged 1.5 h per assay, without requiring cold-chain logistics. This proof-of-concept demonstrates that intracellular parasite DNA can be recovered from canopy surfaces and read out in real-time, providing upstream, landscape-level intelligence to guide targeted vector surveillance in remote settings. Our approach operationalizes One Health by integrating environmental, wildlife, and vector signals within a single technological platform, representing a paradigm shift from reactive, sector-specific surveillance to proactive, integrated pathogen intelligence across the human-animal-environment interface.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"21 ","pages":"Article 101167"},"PeriodicalIF":4.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144895915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Avian influenza spillover into poultry: environmental influences and biosecurity protections","authors":"Matthew Gonnerman ,&nbsp;Jennifer M. Mullinax ,&nbsp;Andrew Fox ,&nbsp;Kelly A. Patyk ,&nbsp;Victoria L. Fields ,&nbsp;Mary-Jane McCool ,&nbsp;Mia K. Torchetti ,&nbsp;Kristina Lantz ,&nbsp;Jeffery D. Sullivan ,&nbsp;Diann J. Prosser","doi":"10.1016/j.onehlt.2025.101172","DOIUrl":"10.1016/j.onehlt.2025.101172","url":null,"abstract":"<div><div>With the continued spread of highly pathogenic avian influenza (HPAI), understanding the complex dynamics of virus transfer at the wild – agriculture interface is paramount. Spillover events (i.e., virus transfer from wild birds into poultry) are related to proximity to infected wild bird populations and environmental conditions. By accounting for such dynamics, we can take a combined approach to assess the impacts of biosecurity measures implemented at poultry farms while simultaneously accounting for their local risk levels. We implemented a Bayesian joint-likelihood logistic regression for the Continental U.S. comparing models of spatiotemporal risk according to land use, weather, and predicted waterfowl distributions followed by integrating a farm-level case-control questionnaire dataset focused on identifying trends in HPAI spillover risk associated with a farm's biosecurity practices. We found that estimates of waterfowl abundance, along with mean precipitation and temperature during winter, were most correlated with spatiotemporal HPAI risk. Additionally, we identified multiple biosecurity practices associated with reduced risk to HPAI, where the strongest relationships were related to litter decontamination treatments, vehicle wash stations, and avoiding shared dead-bird disposal sites with other farms. This model broadly guides surveillance of HPAI in wild and domestic populations, identifying when and where we are most likely to see increased instances of the virus while also providing insights into how poultry farms can better protect themselves from risk.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"21 ","pages":"Article 101172"},"PeriodicalIF":4.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144903143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Infectious disease risk after the October 2024 flash flood in Valencia, Spain: Disaster evolution, strategic scenario analysis, and extrapolative baseline for a One Health assessment","authors":"Santiago Mas-Coma ,&nbsp;Patricio Artigas ,&nbsp;Pablo F. Cuervo ,&nbsp;Alejandra De Elías-Escribano ,&nbsp;M. Cecilia Fantozzi ,&nbsp;Giulia Colangeli ,&nbsp;Angel Córdoba ,&nbsp;Davis J. Marquez-Guzman ,&nbsp;Cristina Mas-Bargues ,&nbsp;Consuelo Borrás ,&nbsp;Patricia Pérez-Pérez ,&nbsp;Carlos J. Bethencourt-Estrella ,&nbsp;Rubén L. Rodríguez-Expósito ,&nbsp;Marco D. Peña-Prunell ,&nbsp;Javier Chao-Pellicer ,&nbsp;Omar García-Pérez ,&nbsp;Angélica T. Domínguez de Barros ,&nbsp;Alma García-Ramos ,&nbsp;Candela Sirvent-Blanco ,&nbsp;Malena Gajeta-Arenas ,&nbsp;M. Dolores Bargues","doi":"10.1016/j.onehlt.2025.101093","DOIUrl":"10.1016/j.onehlt.2025.101093","url":null,"abstract":"<div><div>The flash flood caused by a cold front occurred beside Valencia city, Spain, on 29 October 2024, was of unprecedented devastation, catastrophic effects and health impact. A fast response initiative was launched to assess the risks of individual infections and infectious epidemics. This early release of results is meant to ease the diagnostic work by hospitals dealing with infected patients and helping to improving preventive infrastructures and action protocols. Infectious agents were searched for in environmental samples of flood water, mud and soil collected during the first three post-flood weeks, mainly focusing on affected core areas. The evolving scenario was followed covering previous days, disaster and post-flood days, and throughout subsequent weeks. The affected geography was mapped to assess water flow trajectories and confluent multidisciplinary circumstances related to short-, mid- and long-term infection risks. The appropriate survey planning distinguished four independent river/ravine basins, each one comprising four different types of sylvatic, rural-agricultural-farming, urban, and lake surrounding areas. A schematic workflow for analytical procedures is provided. A wide diversity of infectious agents was found, with higher concentration rates in mud than in flood waters. Environmental samples included viruses, bacteria, protozoans, opportunistic free-living amoebae, helminths, and vector groups of mosquitos, sandflies and freshwater snails. Transmission characteristics, human infection sources and pathogenicity are summarized for each pathogen found. Potentially emerging vector-borne diseases are analyzed. Detected microorganisms are of different transmission types, from direct to zoonotic, infection sources from oral to transcutaneous and wound infection, from short- to long-term life cycles, and from permanent to seasonal transmission. Fecal contamination showed high rates and indicated both human and animal sources, with potential reservoirs such as sheep, goats, pigs, equids, dogs and cats. The very large flooded zone requires a multidisciplinary One Health approach. Many lessons should be learned by both professionals in involved disciplines and related decision makers in governments. The large heterogeneity, complexity and far-reaching health consequences of the disaster furnish an extrapolative baseline model which may be useful to face similar catastrophic climate events in the future, expected to occur according to current climate change trends, both throughout the Mediterranean basin and elsewhere.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"21 ","pages":"Article 101093"},"PeriodicalIF":4.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144270633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Domestic animals and hygiene on infants' risk of contact and exposure to animal faeces in urban neighbourhoods in Kenya: A mixed methods cohort study","authors":"Innocent K. Tumwebaze ,&nbsp;Mark Krysan ,&nbsp;Phylis J. Busienei ,&nbsp;Sheillah Simiyu ,&nbsp;Blessing Mberu ,&nbsp;Daniel K. Sewell ,&nbsp;Kelly K. Baker","doi":"10.1016/j.onehlt.2025.101217","DOIUrl":"10.1016/j.onehlt.2025.101217","url":null,"abstract":"<div><div>Contact with animals or their faeces could expose infants to zoonotic pathogens associated with diarrheal infections in infants. This study investigated the risk of infants' exposure to domestic animals and their faeces in low- and middle-income urban neighbourhoods in Kenya. A total of 275 caregivers with infants aged 0–12 months from low- income and middle-income neighbourhoods in Nairobi and Kisumu were enrolled in a cohort prospective study and completed the survey. Of these, 136 belonged to low-income and 139 to middle-income neighbourhoods. To ensure balanced recruitment of infants in each neighbourhood, community health promoters who provided a listing of caregivers and their infants aged 0–12 months to form the sampling frame. Recruitment was based on the target for each infant age cluster. Negative Binomial, Zero-Inflated Poisson (ZIP), and Zero-Inflated Negative Binomial (ZINB) regression models were used to test for the rate of infant contact (per hour) with animals and animal faeces and logistic regression for infant exposure to surfaces contaminated with animal faeces. Bayes factors were used for model selection. Overall, 27.9 % of the studied low-income neighbourhood households and 30.9 % of those in middle-income neighbourhoods owned domestic animals. Infants in households who owned cats had a 109 % increase (95 %CI = 59 %, 173 %) in contact compared to non-cat owning households. There was a 22 % decrease (95 %CI = 7 %, 42 %) in infant contact with non-feline animals compared to households that did not own them. The rate of contact with animals, animal faeces, or surfaces polluted by animal faeces increased with age. Full penning of household owned animals reduced the rate of infant contact with animal faeces by 93 % (95 %CI = 16 %, 99.7 %), compared to no penning, and reduced the odds of infant contact with a contaminated surface by 97 % (95 %CI = 42 %–99.9 %), compared to no penning. Self-reported animal faeces disposal practices were not significantly associated with a reduced rate of infant contact with animal faeces or touching surfaces contaminated by animal faeces. The study findings infants in households that owned cats have an increased contact with them while full penning of domestic animals is associated with reduced risk of exposure to animal faeces or contaminated surfaces.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"21 ","pages":"Article 101217"},"PeriodicalIF":4.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145104403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Apparent prevalence, lesion distribution and risk factors of bovine tuberculosis in cattle slaughtered at the Shashemene and Arsi Negelle municipal abattoirs, Ethiopia","authors":"Mohammed Desu ,&nbsp;Nigussu Fasil ,&nbsp;Rahmeto Abebe","doi":"10.1016/j.onehlt.2025.101200","DOIUrl":"10.1016/j.onehlt.2025.101200","url":null,"abstract":"<div><div>Bovine tuberculosis (bTB) is a chronic infectious disease caused by <em>Mycobacterium bovis</em>, primarily affecting cattle and presenting a zoonotic risk to humans. It adversely impacts milk and meat production, ultimately jeopardizing food security and livelihoods, particularly in developing countries like Ethiopia, where the disease is endemic. This cross-sectional study, conducted from January to December 2023, aimed to estimate the apparent prevalence of bTB, assess the distribution of lesions, and identify associated risk factors among cattle slaughtered at two municipal abattoirs. The study systematically examined the carcasses of 648 cattle. The results revealed an overall apparent prevalence of bTB of 6.2 % (95 % CI: 4.4 % - 8.3 %), with no significant difference observed between the two abattoirs (<em>p</em> &gt; 0.05). The highest proportion of TB lesions (48.8 %) was identified in the lungs and associated lymph nodes, followed by the mesenteric lymph nodes and livers (29.3 %), and the lymph nodes of the head (21.9 %). Multivariable logistic regression model identified breed and body condition scores as significant risk factors for the apparent prevalence of bTB. Specifically, crossbred cattle were found to be 2.8 times more likely to exhibit TB lesions than Zebus. Additionally, cattle in poor body condition were 8.4 times more likely to show TB lesions compared with those in good condition. These findings highlight the widespread occurrence of bTB among cattle, particularly in crossbred and poorly conditioned animals, with both respiratory and gastrointestinal tract involvement in the disease's spread. The study underscores the urgent need for enhanced control and prevention strategies against bTB in the region.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"21 ","pages":"Article 101200"},"PeriodicalIF":4.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145104258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outbreak of highly pathogenic avian influenza a(H5N1) among house cats: A case series involving oseltamivir treatment","authors":"Jacob F. Gomez ,&nbsp;Ian G. Bemis ,&nbsp;Ismaila Shittu ,&nbsp;Gregory C. Gray ,&nbsp;Kristen K. Coleman","doi":"10.1016/j.onehlt.2025.101211","DOIUrl":"10.1016/j.onehlt.2025.101211","url":null,"abstract":"<div><div>We present a highly pathogenic avian influenza A(H5N1) outbreak among four domestic cats from the same household within close proximity to a dairy farm in Tulare, California – the epicenter of the H5N1 dairy cattle outbreaks in California, USA. We demonstrate that with early supportive care and treatment with oseltamivir, H5N1 is survivable in domestic cats, and that survivor cats may maintain high titers of neutralizing antibodies against H5N1 at least 3–4 months post recovery.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"21 ","pages":"Article 101211"},"PeriodicalIF":4.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145104270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}