Pub Date : 2024-11-12DOI: 10.1016/j.onehlt.2024.100933
Omar Jimenez-Lopez , Tui Ray , Christopher Dean , Ilya Slizovskiy , Jessica Deere , Tiffany Wolf , Seth Moore , Alexander Primus , Jennifer Høy-Petersen , Silje Finstad , Jakob Mo , Henning Sørum , Noelle Noyes
Anthropogenic activities can significantly impact wildlife in natural water bodies, affecting not only the host's physiology but also its microbiome. This study aimed to analyze the gut microbiome and antimicrobial resistance gene profile (i.e., the resistome) of yellow perch living in lakes subjected to different levels of anthropogenic pressure: wastewater effluent-impacted lakes and undeveloped lakes. Total DNA and RNA from gut content samples were extracted and sequenced for analysis. Results indicate that the gut resistome and microbiome of yellow perch differ between lakes, perhaps due to varying anthropogenic pressure. The resistome was predominated by macrolide resistance genes, particularly the MLS23S group, making up 53 % of resistome sequences from effluent-impacted lakes and 73 % from undeveloped lakes. The colistin resistance gene group (mcr) was detected in numerous samples, including variants associated with Aeromonas and the family Enterobacteriaceae. The gut microbiome across all samples was dominated by the phyla Proteobacteria, Firmicutes, and Actinobacteria, with the opportunistic pathogens Plesiomonas shigelloides and Aeromonas veronii more abundant in effluent-impacted lakes. Metagenomic analysis of wild fish samples offers valuable insights into the effects of anthropogenic pressures on microbial communities, including antimicrobial resistance genes, in water bodies.
{"title":"The gut microbiome and resistome of yellow perch (Perca flavescens) living in Minnesota lakes under varying anthropogenic pressure","authors":"Omar Jimenez-Lopez , Tui Ray , Christopher Dean , Ilya Slizovskiy , Jessica Deere , Tiffany Wolf , Seth Moore , Alexander Primus , Jennifer Høy-Petersen , Silje Finstad , Jakob Mo , Henning Sørum , Noelle Noyes","doi":"10.1016/j.onehlt.2024.100933","DOIUrl":"10.1016/j.onehlt.2024.100933","url":null,"abstract":"<div><div>Anthropogenic activities can significantly impact wildlife in natural water bodies, affecting not only the host's physiology but also its microbiome. This study aimed to analyze the gut microbiome and antimicrobial resistance gene profile (i.e., the resistome) of yellow perch living in lakes subjected to different levels of anthropogenic pressure: wastewater effluent-impacted lakes and undeveloped lakes. Total DNA and RNA from gut content samples were extracted and sequenced for analysis. Results indicate that the gut resistome and microbiome of yellow perch differ between lakes, perhaps due to varying anthropogenic pressure. The resistome was predominated by macrolide resistance genes, particularly the MLS23S group, making up 53 % of resistome sequences from effluent-impacted lakes and 73 % from undeveloped lakes. The colistin resistance gene group (<em>mcr</em>) was detected in numerous samples, including variants associated with <em>Aeromonas</em> and the family <em>Enterobacteriaceae</em>. The gut microbiome across all samples was dominated by the phyla Proteobacteria, Firmicutes, and Actinobacteria, with the opportunistic pathogens <em>Plesiomonas shigelloides</em> and <em>Aeromonas veronii</em> more abundant in effluent-impacted lakes. Metagenomic analysis of wild fish samples offers valuable insights into the effects of anthropogenic pressures on microbial communities, including antimicrobial resistance genes, in water bodies.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"19 ","pages":"Article 100933"},"PeriodicalIF":4.1,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142651628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-08DOI: 10.1016/j.onehlt.2024.100929
Caroline Kuhn , Kenneth Mawuta Hayibor , Ama Twumwaa Acheampong , Luciana Salini Abrahão Pires , Magda Clara Vieira Costa-Ribeiro , María Soledad Burrone , Carlos Roberto Vásquez-Almazán , Katja Radon , María Teresa Solis Soto
Background
The recent COVID-19 pandemic and the emergence of infectious diseases at the human-animal interface highlight the global challenge of mitigating zoonotic risks. The One Health approach emphasizes the interconnectedness of human, animal, and environmental health, urging for holistic and interdisciplinary strategies in disease prevention. Despite growing interest, the attention to wildlife in pandemic prevention remains limited. This systematic literature review aims to evaluate recent One Health research on zoonotic diseases and wildlife in terms of study design, interdisciplinary collaboration, and participatory approaches. Key questions addressed include the consideration of One Health domains, disciplinary involvement, and the inclusion of non-academic stakeholders.
Methods
Following PRISMA guidelines, PubMed and Web of Science were searched for primary research papers on zoonotic diseases and wildlife from 2018 to 2023. Eligibility criteria included a focus on wildlife, zoonotic diseases, and adoption of the One Health approach.
Results
A total of 228 primary research papers were retrieved. Out of these, 105 studies were included in the review. Few studies integrated human, animal, and environmental domains simultaneously in data collection (4.8 %) and knowledge generation (29.5 %). While extensive knowledge was generated for animal health (97.1 %) and human health (84.8 %), environmental health (34.3 %) remained underrepresented. Laboratory methods predominated (82.9 %), with limited integration of social science methodologies (19 %). The majority were epidemiological studies (86.7 %), yet analytical design within these was sparse (17.1 %). Participation of non-academic stakeholders was limited (36.2 % included non-academics; 3.8 % encompassed participative approaches).
Conclusions
The synthesis of the domains human, animal and environmental health remained fragmentary in the studies reviewed. Environmental health is underrepresented and the interdisciplinary involvement of social sciences lacks. Neglecting these fields of competence impedes comprehensive understanding of disease dynamics and hampers effective zoonosis prevention strategies. In result, greater inter- and transdisciplinary collaboration, along with participatory approaches, are still needed for advancing One Health research.
{"title":"How studies on zoonotic risks in wildlife implement the one health approach – A systematic review","authors":"Caroline Kuhn , Kenneth Mawuta Hayibor , Ama Twumwaa Acheampong , Luciana Salini Abrahão Pires , Magda Clara Vieira Costa-Ribeiro , María Soledad Burrone , Carlos Roberto Vásquez-Almazán , Katja Radon , María Teresa Solis Soto","doi":"10.1016/j.onehlt.2024.100929","DOIUrl":"10.1016/j.onehlt.2024.100929","url":null,"abstract":"<div><h3>Background</h3><div>The recent COVID-19 pandemic and the emergence of infectious diseases at the human-animal interface highlight the global challenge of mitigating zoonotic risks. The One Health approach emphasizes the interconnectedness of human, animal, and environmental health, urging for holistic and interdisciplinary strategies in disease prevention. Despite growing interest, the attention to wildlife in pandemic prevention remains limited. This systematic literature review aims to evaluate recent One Health research on zoonotic diseases and wildlife in terms of study design, interdisciplinary collaboration, and participatory approaches. Key questions addressed include the consideration of One Health domains, disciplinary involvement, and the inclusion of non-academic stakeholders.</div></div><div><h3>Methods</h3><div>Following PRISMA guidelines, PubMed and Web of Science were searched for primary research papers on zoonotic diseases and wildlife from 2018 to 2023. Eligibility criteria included a focus on wildlife, zoonotic diseases, and adoption of the One Health approach.</div></div><div><h3>Results</h3><div>A total of 228 primary research papers were retrieved. Out of these, 105 studies were included in the review. Few studies integrated human, animal, and environmental domains simultaneously in data collection (4.8 %) and knowledge generation (29.5 %). While extensive knowledge was generated for animal health (97.1 %) and human health (84.8 %), environmental health (34.3 %) remained underrepresented. Laboratory methods predominated (82.9 %), with limited integration of social science methodologies (19 %). The majority were epidemiological studies (86.7 %), yet analytical design within these was sparse (17.1 %). Participation of non-academic stakeholders was limited (36.2 % included non-academics; 3.8 % encompassed participative approaches).</div></div><div><h3>Conclusions</h3><div>The synthesis of the domains human, animal and environmental health remained fragmentary in the studies reviewed. Environmental health is underrepresented and the interdisciplinary involvement of social sciences lacks. Neglecting these fields of competence impedes comprehensive understanding of disease dynamics and hampers effective zoonosis prevention strategies. In result, greater inter- and transdisciplinary collaboration, along with participatory approaches, are still needed for advancing One Health research.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"19 ","pages":"Article 100929"},"PeriodicalIF":4.1,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142650832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-07DOI: 10.1016/j.onehlt.2024.100927
Aileen M. Marty , Christian K. Beÿ , Kristi L. Koenig
The declaration of a second Public Health Emergency of International Concern (PHEIC) for mpox in August 2024 underscores the urgent need for a comprehensive understanding of the evolving epidemiology [1] clinical manifestations, and zoonotic potential of this emerging threat [2]. This work delves into the intricate interplay between human and animal mpox infections, with a specific focus on the unique characteristics of various viral clades and their implications for individual and public health.
There is a critical need to elucidate the factors driving multiple spillover events and the subsequent emergence of new clades better adapted to human-to-human transmission. We hypothesize that anthropogenic changes, including deforestation, urbanization, and climate change are facilitating increased human-to-animal contact, leading to more frequent zoonotic transmissions and viral adaptations. Our conceptual framework integrates One Health principles, evolutionary virology, and epidemiological modeling to investigate the demographic, clinical, and treatment differences among mpox clades in both humans and animals. We employ a mixed-methods approach, combining genomic analysis, clinical data review, and ecological surveys to construct a comprehensive picture of mpox's changing dynamics. The research questions explore the differences in epidemiological and clinical profiles among mpox clades and the factors that likely contribute to successful cross-species transmission and human adaptation.
This manuscript introduces an updated Identify, Isolate, Inform (3I) Tool meticulously redesigned to significantly improve the early detection, containment, and reporting of mpox cases across diverse settings. By integrating clinical, virological, and ecological data, this work aims to lay the groundwork for enhanced risk assessment, targeted interventions, and global preparedness strategies in the face of this evolving zoonotic threat.
{"title":"2024 Mpox outbreak: A rapidly evolving public health emergency of international concern: Introduction of an Updated Mpox Identify-Isolate-Inform (3I) Tool","authors":"Aileen M. Marty , Christian K. Beÿ , Kristi L. Koenig","doi":"10.1016/j.onehlt.2024.100927","DOIUrl":"10.1016/j.onehlt.2024.100927","url":null,"abstract":"<div><div>The declaration of a second Public Health Emergency of International Concern (PHEIC) for mpox in August 2024 underscores the urgent need for a comprehensive understanding of the evolving epidemiology [<span><span>1</span></span>] clinical manifestations, and zoonotic potential of this emerging threat [<span><span>2</span></span>]. This work delves into the intricate interplay between human and animal mpox infections, with a specific focus on the unique characteristics of various viral clades and their implications for individual and public health.</div><div>There is a critical need to elucidate the factors driving multiple spillover events and the subsequent emergence of new clades better adapted to human-to-human transmission. We hypothesize that anthropogenic changes, including deforestation, urbanization, and climate change are facilitating increased human-to-animal contact, leading to more frequent zoonotic transmissions and viral adaptations. Our conceptual framework integrates One Health principles, evolutionary virology, and epidemiological modeling to investigate the demographic, clinical, and treatment differences among mpox clades in both humans and animals. We employ a mixed-methods approach, combining genomic analysis, clinical data review, and ecological surveys to construct a comprehensive picture of mpox's changing dynamics. The research questions explore the differences in epidemiological and clinical profiles among mpox clades and the factors that likely contribute to successful cross-species transmission and human adaptation.</div><div>This manuscript introduces an updated Identify, Isolate, Inform (3I) Tool meticulously redesigned to significantly improve the early detection, containment, and reporting of mpox cases across diverse settings. By integrating clinical, virological, and ecological data, this work aims to lay the groundwork for enhanced risk assessment, targeted interventions, and global preparedness strategies in the face of this evolving zoonotic threat.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"19 ","pages":"Article 100927"},"PeriodicalIF":4.1,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142650888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The evolution of the global scenario, which involves such converging crises as the climate crisis, the COVID-19 pandemic and its aftermath, and the Russia-Ukraine and Israel-Palestine wars, has underscored the fragility of the current food systems and the interdependence of human, animal, plant, and environmental health. Plant health is an important element in all these crises as plants provide food and feed, fix CO2, produce oxygen, and stabilize the soil. As a result of the Covid 19 pandemic, the One Health concept has finally obtained the attention of scientists and funding agencies. However, despite their role in global nutrition, the economy, and in climate crisis, plants are often excluded from the One Health efforts and funding streams. This paper advocates the need for an updated and more holistic view of plant health as public goods within the context of the evolving global challenges and explores opportunities within the Circular Health paradigm.
{"title":"Positioning plant health within the evolving human-animal-environmental health paradigms","authors":"Maria Lodovica Gullino , Matias Pasquali , Massimo Pugliese , Ilaria Capua","doi":"10.1016/j.onehlt.2024.100931","DOIUrl":"10.1016/j.onehlt.2024.100931","url":null,"abstract":"<div><div>The evolution of the global scenario, which involves such converging crises as the climate crisis, the COVID-19 pandemic and its aftermath, and the Russia-Ukraine and Israel-Palestine wars, has underscored the fragility of the current food systems and the interdependence of human, animal, plant, and environmental health. Plant health is an important element in all these crises as plants provide food and feed, fix CO<sub>2</sub>, produce oxygen, and stabilize the soil. As a result of the Covid 19 pandemic, the One Health concept has finally obtained the attention of scientists and funding agencies. However, despite their role in global nutrition, the economy, and in climate crisis, plants are often excluded from the One Health efforts and funding streams. This paper advocates the need for an updated and more holistic view of plant health as public goods within the context of the evolving global challenges and explores opportunities within the Circular Health paradigm.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"19 ","pages":"Article 100931"},"PeriodicalIF":4.1,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142650834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-05DOI: 10.1016/j.onehlt.2024.100930
Nicholas K.Y. Yuen , Jessica J. Harrison , Althea S.W. Wang , Isabella E. McMahon , Gervais Habarugira , Mitchell P. Coyle , Helle Bielefeldt-Ohmann
An incursion and outbreak of Japanese encephalitis virus (JEV) was reported in Australia in 2021 and 2022, respectively. There was speculation that JEV may have been circulating in Australia unknowingly prior to the detection. In this study, we determined sero-prevalence and transmission of West Nile virus (WNV), Murray Valley encephalitis virus (MVEV) and JEV, prior to and post JEV incursion in a sentinel equine population in south-east Queensland (SEQ), Australia, using blocking ELISAs (screening test) and virus neutralisation test (confirmatory). Serum samples collected between 2018 and 2020 (prior to JEV incursion; n = 607) from horses residing in SEQ revealed that sero-prevalence to pathogenic orthoflaviviruses was low, specifically WNV (1.3 %; 8/607), MVEV (1.2 %; 7/607), and JEV (4.9 %; 30/607). The significantly higher prevalence of JEV (P < 0.05) was skewed by the high proportion of horses previously enrolled in one or more JEV vaccine studies (17/30; 56.7 %) and the unknown JEV vaccination history due to international travel (6/30; 20 %). Thirty-two foals were enrolled as sentinels to monitor for arbovirus transmissions in SEQ between 2020 and 2023. Results showed that JEV seroconversion was first detected in April 2022 (n = 4), with seven more seroconversions detected in the following months until November 2022. This study (i) confirms that it is highly unlikely that JEV incursion in SEQ occurred prior to February 2022; (ii) circulation of WNV in SEQ remains very low; and (iii) highlights the complexity in the interpretation of orthoflavivirus serological results. The authors propose that horses should be included as sentinels for arbovirus transmission monitoring in Australia.
{"title":"Orthoflavivirus circulation in South-East Queensland, Australia, before and during the 2021–2022 incursion of Japanese encephalitis virus assessed through sero-epidemiological survey of a sentinel equine population","authors":"Nicholas K.Y. Yuen , Jessica J. Harrison , Althea S.W. Wang , Isabella E. McMahon , Gervais Habarugira , Mitchell P. Coyle , Helle Bielefeldt-Ohmann","doi":"10.1016/j.onehlt.2024.100930","DOIUrl":"10.1016/j.onehlt.2024.100930","url":null,"abstract":"<div><div>An incursion and outbreak of Japanese encephalitis virus (JEV) was reported in Australia in 2021 and 2022, respectively. There was speculation that JEV may have been circulating in Australia unknowingly prior to the detection. In this study, we determined sero-prevalence and transmission of West Nile virus (WNV), Murray Valley encephalitis virus (MVEV) and JEV, prior to and post JEV incursion in a sentinel equine population in south-east Queensland (SEQ), Australia, using blocking ELISAs (screening test) and virus neutralisation test (confirmatory). Serum samples collected between 2018 and 2020 (prior to JEV incursion; <em>n</em> = 607) from horses residing in SEQ revealed that sero-prevalence to pathogenic orthoflaviviruses was low, specifically WNV (1.3 %; 8/607), MVEV (1.2 %; 7/607), and JEV (4.9 %; 30/607). The significantly higher prevalence of JEV (<em>P</em> < 0.05) was skewed by the high proportion of horses previously enrolled in one or more JEV vaccine studies (17/30; 56.7 %) and the unknown JEV vaccination history due to international travel (6/30; 20 %). Thirty-two foals were enrolled as sentinels to monitor for arbovirus transmissions in SEQ between 2020 and 2023. Results showed that JEV seroconversion was first detected in April 2022 (<em>n</em> = 4), with seven more seroconversions detected in the following months until November 2022. This study (i) confirms that it is highly unlikely that JEV incursion in SEQ occurred prior to February 2022; (ii) circulation of WNV in SEQ remains very low; and (iii) highlights the complexity in the interpretation of orthoflavivirus serological results. The authors propose that horses should be included as sentinels for arbovirus transmission monitoring in Australia.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"19 ","pages":"Article 100930"},"PeriodicalIF":4.1,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142651627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-03DOI: 10.1016/j.onehlt.2024.100926
Igori Balta , Joanne Lemon , Ciara Murnane , Ioan Pet , Teodor Vintila , David McCleery , Todd Callaway , Alastair Douglas , Lavinia Stef , Nicolae Corcionivoschi
The ongoing effects of climate change have exacerbated two significant challenges to global populations: the transmission of foodborne pathogens and antimicrobial resistance (AMR) through the food chain. Using the latest available scientific information this review explores how climate-related factors such as rainfall, floods, storms, hurricanes, cyclones, dust, temperature and humidity impact the spread of the foodborne pathogens Salmonella, E. coli, Campylobacter, Vibrio, Listeria, and Staphylococcus aureus. We explore the complex dynamics between environmental changes and the heightened risk of foodborne diseases, analysing the contribution of wildlife, insects and contaminated environments in the proliferation of AMR and climate change. This review paper combines a thorough analysis of current literature with a discussion on findings from a wide variety of studies to provide a comprehensive overview of how climatic factors contribute to the survival, persistence and transmission of bacterial pathogens in the food chain. In addition, we discuss the necessity for effective mitigation strategies and policies. By providing insights into the interrelationships between climate change and food safety, this review hopes to inform future research and policy development to promote safer and more sustainable food systems and further integration within the One Health approach.
气候变化的持续影响加剧了全球人口面临的两大挑战：食源性病原体的传播和通过食物链产生的抗菌药耐药性（AMR）。本综述利用现有的最新科学信息，探讨了降雨、洪水、风暴、飓风、气旋、沙尘、温度和湿度等气候相关因素如何影响食源性病原体沙门氏菌、大肠杆菌、弯曲杆菌、弧菌、李斯特菌和金黄色葡萄球菌的传播。我们探讨了环境变化与食源性疾病风险增加之间的复杂动态关系，分析了野生动物、昆虫和受污染环境在 AMR 扩散和气候变化中的作用。这篇综述论文结合了对当前文献的透彻分析和对各种研究结果的讨论，全面概述了气候因素是如何促成细菌病原体在食物链中的生存、持续存在和传播的。此外，我们还讨论了有效缓解战略和政策的必要性。通过深入探讨气候变化与食品安全之间的相互关系，本综述希望为未来的研究和政策制定提供信息，以促进更安全、更可持续的食品系统，并进一步融入 "一个健康 "方法。
{"title":"The One Health aspect of climate events with impact on foodborne pathogens transmission","authors":"Igori Balta , Joanne Lemon , Ciara Murnane , Ioan Pet , Teodor Vintila , David McCleery , Todd Callaway , Alastair Douglas , Lavinia Stef , Nicolae Corcionivoschi","doi":"10.1016/j.onehlt.2024.100926","DOIUrl":"10.1016/j.onehlt.2024.100926","url":null,"abstract":"<div><div>The ongoing effects of climate change have exacerbated two significant challenges to global populations: the transmission of foodborne pathogens and antimicrobial resistance (AMR) through the food chain. Using the latest available scientific information this review explores how climate-related factors such as rainfall, floods, storms, hurricanes, cyclones, dust, temperature and humidity impact the spread of the foodborne pathogens <em>Salmonella</em>, <em>E. coli</em>, <em>Campylobacter</em>, <em>Vibrio</em>, <em>Listeria</em>, and <em>Staphylococcus aureus</em>. We explore the complex dynamics between environmental changes and the heightened risk of foodborne diseases, analysing the contribution of wildlife, insects and contaminated environments in the proliferation of AMR and climate change. This review paper combines a thorough analysis of current literature with a discussion on findings from a wide variety of studies to provide a comprehensive overview of how climatic factors contribute to the survival, persistence and transmission of bacterial pathogens in the food chain. In addition, we discuss the necessity for effective mitigation strategies and policies. By providing insights into the interrelationships between climate change and food safety, this review hopes to inform future research and policy development to promote safer and more sustainable food systems and further integration within the One Health approach.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"19 ","pages":"Article 100926"},"PeriodicalIF":4.1,"publicationDate":"2024-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142592599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-02DOI: 10.1016/j.onehlt.2024.100925
Stef Bronzwaer , Wim de Coen , Ole Heuer , Ian Marnane , Ana Vidal
The Cross-agency One Health Task Force, established by five EU agencies (ECDC, ECHA, EEA, EFSA and EMA), has released its Framework for Action, aimed at operationalising the One Health approach across various EU regulatory science sectors. This initiative, originating from the 2022 ONE Conference, addresses the integration of human, animal, plant, and environmental health inspired by the European Green Deal. The framework outlines five strategic objectives: enhancing strategic coordination, promoting research, strengthening capacity building, fostering communication and partnerships, as well as joint activities. These objectives will align the agencies' efforts, improve collaboration, and promote a transdisciplinary approach to address health threats. Key actions for 2024–2026 include developing joint publications, research coordination, and One Health-driven training programs. The Task Force will coordinate its work through regular interactions, in close liaison with the European Commission, to ensure long-term interdisciplinary cooperation.
{"title":"The framework for action of the Cross-agency One Health Task Force","authors":"Stef Bronzwaer , Wim de Coen , Ole Heuer , Ian Marnane , Ana Vidal","doi":"10.1016/j.onehlt.2024.100925","DOIUrl":"10.1016/j.onehlt.2024.100925","url":null,"abstract":"<div><div>The Cross-agency One Health Task Force, established by five EU agencies (ECDC, ECHA, EEA, EFSA and EMA), has released its Framework for Action, aimed at operationalising the One Health approach across various EU regulatory science sectors. This initiative, originating from the 2022 ONE Conference, addresses the integration of human, animal, plant, and environmental health inspired by the European Green Deal. The framework outlines five strategic objectives: enhancing strategic coordination, promoting research, strengthening capacity building, fostering communication and partnerships, as well as joint activities. These objectives will align the agencies' efforts, improve collaboration, and promote a transdisciplinary approach to address health threats. Key actions for 2024–2026 include developing joint publications, research coordination, and One Health-driven training programs. The Task Force will coordinate its work through regular interactions, in close liaison with the European Commission, to ensure long-term interdisciplinary cooperation.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"19 ","pages":"Article 100925"},"PeriodicalIF":4.1,"publicationDate":"2024-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142651629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-30DOI: 10.1016/j.onehlt.2024.100924
Gloria Herrero-García , Marta Pérez-Sancho , Patricia Barroso , Carmen Herranz-Benito , David Relimpio , Teresa García-Seco , Alberto Perelló , Alberto Díez-Guerrier , Pilar Pozo , Ana Balseiro , Lucas Domínguez , Christian Gortázar
Outdoor farming contributes to biodiversity conservation and enhances animal welfare, but also raises biosafety concerns due to livestock contact with potentially infected wildlife. Thus, there is a need to assess the balance between vertebrate species richness on farms, visits by wildlife species posing a biosafety risk, and pathogen circulation in open-air farming systems. We explored these links in a pilot study involving 15 open-air hoofstock farms (6 cattle, 5 small ruminant, and 4 pig farms), where we conducted interviews and risk point inspections and used two noninvasive tools: short-term camera trap (CT) deployment and environmental nucleic acid detection (ENAD). CTs were deployed to assess the richness of birds and mammals, as well as to determine the percentage of CTs detecting defined risk species. We also collected livestock feces and used sponges to sample surfaces for environmental DNA (eDNA), testing for nine pathogen markers. Total vertebrate richness ranged from 18 to 42 species, with waterholes significantly contributing to farm vertebrate richness, since 48.2 % of all wild vertebrates were detected at waterbodies, and 28.6 % were exclusively detected at waterholes. Pathogen markers detected at risk points correlated with those detected in livestock samples. Notably, the frequency of uidA marker detection correlated with the total number of pathogen markers detected per farm. Overall marker richness, an indicator of pathogen diversity, varied between farms, being higher in small ruminant farms compared to cattle or pig farms. At the farm level, wild vertebrate richness was negatively correlated with the richness of pathogen markers detected at risk points. Additionally, risk points with a higher probability of detecting more pathogen markers had lower vertebrate richness. Although CT-based assessments of vertebrate richness and ENAD-based pathogen marker detection are only indicators of actual biodiversity and farm health, respectively, our findings suggest that farmland vertebrate communities provide important ecosystem services and may help limit the circulation of multi-host pathogens.
{"title":"One Health Farming: Noninvasive monitoring reveals links between farm vertebrate richness and pathogen markers in outdoor hoofstock","authors":"Gloria Herrero-García , Marta Pérez-Sancho , Patricia Barroso , Carmen Herranz-Benito , David Relimpio , Teresa García-Seco , Alberto Perelló , Alberto Díez-Guerrier , Pilar Pozo , Ana Balseiro , Lucas Domínguez , Christian Gortázar","doi":"10.1016/j.onehlt.2024.100924","DOIUrl":"10.1016/j.onehlt.2024.100924","url":null,"abstract":"<div><div>Outdoor farming contributes to biodiversity conservation and enhances animal welfare, but also raises biosafety concerns due to livestock contact with potentially infected wildlife. Thus, there is a need to assess the balance between vertebrate species richness on farms, visits by wildlife species posing a biosafety risk, and pathogen circulation in open-air farming systems. We explored these links in a pilot study involving 15 open-air hoofstock farms (6 cattle, 5 small ruminant, and 4 pig farms), where we conducted interviews and risk point inspections and used two noninvasive tools: short-term camera trap (CT) deployment and environmental nucleic acid detection (ENAD). CTs were deployed to assess the richness of birds and mammals, as well as to determine the percentage of CTs detecting defined risk species. We also collected livestock feces and used sponges to sample surfaces for environmental DNA (eDNA), testing for nine pathogen markers. Total vertebrate richness ranged from 18 to 42 species, with waterholes significantly contributing to farm vertebrate richness, since 48.2 % of all wild vertebrates were detected at waterbodies, and 28.6 % were exclusively detected at waterholes. Pathogen markers detected at risk points correlated with those detected in livestock samples. Notably, the frequency of uidA marker detection correlated with the total number of pathogen markers detected per farm. Overall marker richness, an indicator of pathogen diversity, varied between farms, being higher in small ruminant farms compared to cattle or pig farms. At the farm level, wild vertebrate richness was negatively correlated with the richness of pathogen markers detected at risk points. Additionally, risk points with a higher probability of detecting more pathogen markers had lower vertebrate richness. Although CT-based assessments of vertebrate richness and ENAD-based pathogen marker detection are only indicators of actual biodiversity and farm health, respectively, our findings suggest that farmland vertebrate communities provide important ecosystem services and may help limit the circulation of multi-host pathogens.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"19 ","pages":"Article 100924"},"PeriodicalIF":4.1,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142572740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-28DOI: 10.1016/j.onehlt.2024.100923
Ruiya Li , Alexander Tendu , Yakhouba Kane , Victor Omondi , Jiaxu Ying , Lingjing Mao , Shiman Xu , Rong Xu , Xing Chen , Yanhua Chen , Stéphane Descorps-Declère , Kathrina Mae Bienes , Meriem Fassatoui , Alice C. Hughes , Nicolas Berthet , Gary Wong
Coronaviruses (CoVs) pose a threat to human health globally, as highlighted by severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS) and the COVID-19 pandemic. Bats from the Greater Mekong Subregion (GMS) are an important natural reservoir for CoVs. Here we report the differential prevalence of CoVs in bats within Yunnan Province across biological and ecological variables. We also show the coexistence of CoVs in individual bats and identify an additional putative host for SARS-related CoV, with higher dispersal capacity than other known hosts. Notably, 11 SARS-related coronaviruses (SARSr-CoVs) were discovered in horseshoe bats (family Rhinolophidae) and a Chinese water myotis bat (Myotis laniger) by pan-CoV detection and Illumina sequencing. Our findings facilitate an understanding of the fundamental features of the distribution and circulation of CoVs in nature as well as zoonotic spillover risk in the One health framework.
{"title":"Differential prevalence and risk factors for infection with coronaviruses in bats collected from Yunnan Province, China","authors":"Ruiya Li , Alexander Tendu , Yakhouba Kane , Victor Omondi , Jiaxu Ying , Lingjing Mao , Shiman Xu , Rong Xu , Xing Chen , Yanhua Chen , Stéphane Descorps-Declère , Kathrina Mae Bienes , Meriem Fassatoui , Alice C. Hughes , Nicolas Berthet , Gary Wong","doi":"10.1016/j.onehlt.2024.100923","DOIUrl":"10.1016/j.onehlt.2024.100923","url":null,"abstract":"<div><div>Coronaviruses (CoVs) pose a threat to human health globally, as highlighted by severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS) and the COVID-19 pandemic. Bats from the Greater Mekong Subregion (GMS) are an important natural reservoir for CoVs. Here we report the differential prevalence of CoVs in bats within Yunnan Province across biological and ecological variables. We also show the coexistence of CoVs in individual bats and identify an additional putative host for SARS-related CoV, with higher dispersal capacity than other known hosts. Notably, 11 SARS-related coronaviruses (SARSr-CoVs) were discovered in horseshoe bats (family <em>Rhinolophidae</em>) and a Chinese water myotis bat (<em>Myotis laniger</em>) by pan-CoV detection and Illumina sequencing. Our findings facilitate an understanding of the fundamental features of the distribution and circulation of CoVs in nature as well as zoonotic spillover risk in the One health framework.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"19 ","pages":"Article 100923"},"PeriodicalIF":4.1,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142650833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-24DOI: 10.1016/j.onehlt.2024.100922
C. Goulet , M. de Garine-Wichatitsky , P. Chardonnet , L.-M. de Klerk , R. Kock , S. Muset , R. Suu-Ire , A. Caron
Wildlife is an essential component of biodiversity and provides people with multiple social and economic benefits. However, a resurgence of epidemics over the past two decades has highlighted wildlife's role as a potential source of dangerous pathogens for humans and livestock, with devastating consequences worldwide. Simultaneously, numerous reports have indicated that wildlife populations are declining at an alarming rate due to human and livestock pathogens, predation, and competition. An integrated approach to managing wildlife, human, and domestic animal health is therefore clearly needed. Yet this integration often fails to materialize due to a lack of wildlife health standards and know-how. Here, we present an operational framework that follows a step-by-step approach: i) a holistic definition of human health is adapted to the context of other-than-human animals, including wildlife; then, ii) different categories of wildlife living within a landscape or a country are defined based on the management systems under which they live. For each wildlife category, the type (natural vs. anthropogenic) of habitat, the nature of the interface of wildlife with humans and/or livestock, and the level of sanitary control are defined; and finally, iii) the holistic definition of wildlife health is considered in relation to each wildlife category to define health challenges and the domains of expertise required to address them. This framework can assist national and international agencies, including veterinary and wildlife authorities and policy makers, in defining wildlife health priorities, responsibilities, policies and capacity building strategies. The extensive interdisciplinary collaboration needed to manage the many different aspects of wildlife health calls for a more integrated One Health approach.
{"title":"An operational framework for wildlife health in the One Health approach","authors":"C. Goulet , M. de Garine-Wichatitsky , P. Chardonnet , L.-M. de Klerk , R. Kock , S. Muset , R. Suu-Ire , A. Caron","doi":"10.1016/j.onehlt.2024.100922","DOIUrl":"10.1016/j.onehlt.2024.100922","url":null,"abstract":"<div><div>Wildlife is an essential component of biodiversity and provides people with multiple social and economic benefits. However, a resurgence of epidemics over the past two decades has highlighted wildlife's role as a potential source of dangerous pathogens for humans and livestock, with devastating consequences worldwide. Simultaneously, numerous reports have indicated that wildlife populations are declining at an alarming rate due to human and livestock pathogens, predation, and competition. An integrated approach to managing wildlife, human, and domestic animal health is therefore clearly needed. Yet this integration often fails to materialize due to a lack of wildlife health standards and know-how. Here, we present an operational framework that follows a step-by-step approach: i) a holistic definition of human health is adapted to the context of other-than-human animals, including wildlife; then, ii) different categories of wildlife living within a landscape or a country are defined based on the management systems under which they live. For each wildlife category, the type (natural vs. anthropogenic) of habitat, the nature of the interface of wildlife with humans and/or livestock, and the level of sanitary control are defined; and finally, iii) the holistic definition of wildlife health is considered in relation to each wildlife category to define health challenges and the domains of expertise required to address them. This framework can assist national and international agencies, including veterinary and wildlife authorities and policy makers, in defining wildlife health priorities, responsibilities, policies and capacity building strategies. The extensive interdisciplinary collaboration needed to manage the many different aspects of wildlife health calls for a more integrated One Health approach.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"19 ","pages":"Article 100922"},"PeriodicalIF":4.1,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142554597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
扫码关注我们
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号