Pub Date : 2025-04-01Epub Date: 2025-01-11DOI: 10.1016/j.pdj.2024.100338
Anum Khan, Ghaida Al-Jaddir, Jo Maynard, Hani Dajani, Kathleen Villanueva, Kate Barnard, Jacqui Gillet
Burkitt’s lymphoma (BL) is a non-Hodgkin Lymphoma (NHL) type fast growing neoplasm of the B-cells and is one of the most common subtypes of paediatric lymphomas. A case of 5 years old female presenting with pain and abnormal teeth mobility in the mandible and swelling of right eye. The initial presentation coincided with multiple organ involvement and urgent referral to Oncology was made. Chemotherapy was initiated and patient was in remission within two months, remains in remission 22 months later. This case reports stresses on dentists and GP recognising signs of abnormal presentations and referring to relevant specialities to ensure early detection and management.
{"title":"Oral manifestations of Burkitts Lymphoma - Literature review and case report of Burkitt's lymphoma in a 5 years old female","authors":"Anum Khan, Ghaida Al-Jaddir, Jo Maynard, Hani Dajani, Kathleen Villanueva, Kate Barnard, Jacqui Gillet","doi":"10.1016/j.pdj.2024.100338","DOIUrl":"10.1016/j.pdj.2024.100338","url":null,"abstract":"<div><div>Burkitt’s lymphoma (BL) is a non-Hodgkin Lymphoma (NHL) type fast growing neoplasm of the B-cells and is one of the most common subtypes of paediatric lymphomas. A case of 5 years old female presenting with pain and abnormal teeth mobility in the mandible and swelling of right eye. The initial presentation coincided with multiple organ involvement and urgent referral to Oncology was made. Chemotherapy was initiated and patient was in remission within two months, remains in remission 22 months later. This case reports stresses on dentists and GP recognising signs of abnormal presentations and referring to relevant specialities to ensure early detection and management.</div></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"35 1","pages":"Article 100338"},"PeriodicalIF":0.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143135830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Periodontal ligament (PDL) damage caused by dental trauma can lead to local circulatory disorders. The mechanisms through which PDL cells, once exposed to a transient hypoxic environment, contribute to tissue regeneration or resorption of pathological tooth roots after reoxygenation remain unclear. Therefore, we aimed to examine how changes in oxygen (O2) concentration affect PDL healing.
Materials and methods
Human PDL stem cells (hPDL cells) were cultured under normoxic or hypoxic (20% or 1% O2 concentration) conditions. Vascular endothelial growth factor (VEGF) and receptor activator of nuclear factor kappa-Β ligand (RANKL) expressions were measured using real-time quantitative polymerase chain reaction or Western blotting. Furthermore, a co-culture of hPDL and osteoclast precursor cells was used to demonstrate the effect of changes in O2 concentration on osteoclast formation.
Results
VEGF expression considerably increased over time under hypoxia compared with normoxia. However, during reoxygenation (24 h hypoxia–24 h normoxia), expression markedly decreased under hypoxia. No significant difference in RANKL expression was observed in both conditions after 24 h; however, it remarkably increased under hypoxia compared with normoxia after 48 h. In the osteoclast formation assay, the number of tartrate-resistant acid phosphatase (TRAP)-positive multinucleated cells considerably increased over time under hypoxia compared with normoxia. Notably, when VEGF expression was reduced using small interfering RNA, the number of TRAP-positive multinucleated cells decreased extensively.
Conclusion
Under hypoxic conditions, periodontal ligament cells produce VEGF to promote angiogenesis. However, excessive VEGF production, along with RANKL production, induces osteoclast formation. Osteoclast formation can be suppressed using rapid reoxygenation.
{"title":"Hypoxia enhances osteoclastogenesis in periodontal ligament cells via expression of VEGF and RANKL","authors":"Kenchi Hase , Misa Ishiyama , Shoko Ozawa , Yoshitaka Yoshimura , Takashi Kikuiri","doi":"10.1016/j.pdj.2024.100336","DOIUrl":"10.1016/j.pdj.2024.100336","url":null,"abstract":"<div><h3>Introduction</h3><div>Periodontal ligament (PDL) damage caused by dental trauma can lead to local circulatory disorders. The mechanisms through which PDL cells, once exposed to a transient hypoxic environment, contribute to tissue regeneration or resorption of pathological tooth roots after reoxygenation remain unclear. Therefore, we aimed to examine how changes in oxygen (O<sub>2</sub>) concentration affect PDL healing.</div></div><div><h3>Materials and methods</h3><div>Human PDL stem cells (hPDL cells) were cultured under normoxic or hypoxic (20% or 1% O<sub>2</sub> concentration) conditions. Vascular endothelial growth factor (VEGF) and receptor activator of nuclear factor kappa-Β ligand (RANKL) expressions were measured using real-time quantitative polymerase chain reaction or Western blotting. Furthermore, a co-culture of hPDL and osteoclast precursor cells was used to demonstrate the effect of changes in O<sub>2</sub> concentration on osteoclast formation.</div></div><div><h3>Results</h3><div>VEGF expression considerably increased over time under hypoxia compared with normoxia. However, during reoxygenation (24 h hypoxia–24 h normoxia), expression markedly decreased under hypoxia. No significant difference in RANKL expression was observed in both conditions after 24 h; however, it remarkably increased under hypoxia compared with normoxia after 48 h. In the osteoclast formation assay, the number of tartrate-resistant acid phosphatase (TRAP)-positive multinucleated cells considerably increased over time under hypoxia compared with normoxia. Notably, when VEGF expression was reduced using small interfering RNA, the number of TRAP-positive multinucleated cells decreased extensively.</div></div><div><h3>Conclusion</h3><div>Under hypoxic conditions, periodontal ligament cells produce VEGF to promote angiogenesis. However, excessive VEGF production, along with RANKL production, induces osteoclast formation. Osteoclast formation can be suppressed using rapid reoxygenation.</div></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"35 1","pages":"Article 100336"},"PeriodicalIF":0.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143135831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tooth anomalies may occur during the various developmental stages.
Case presentation
A 2Y3M-old Japanese girl came to our clinic. At 1Y8M, the mandibular left primary central incisor had erupted with little or no crown formation, and also showed dysplasia and pulp exposure. Root canal treatment was performed at the first visit, with crown restoration performed with composite resin. The permanent tooth germ showed the same development as the contralateral one.
Conclusion
Symptoms observed in the affected tooth were somewhat similar to those in regional odontodysplasia cases. Careful follow-up examinations until permanent tooth replacement will be necessary.
{"title":"Developmental abnormality localized to mandibular left primary incisor","authors":"Tamami Kadota, Marin Ochiai, Misato Takagi, Maika Fujisaki, Rena Okawa, Kazuhiko Nakano","doi":"10.1016/j.pdj.2024.11.003","DOIUrl":"10.1016/j.pdj.2024.11.003","url":null,"abstract":"<div><h3>Background</h3><div>Tooth anomalies may occur during the various developmental stages.</div></div><div><h3>Case presentation</h3><div>A 2Y3M-old Japanese girl came to our clinic. At 1Y8M, the mandibular left primary central incisor had erupted with little or no crown formation, and also showed dysplasia and pulp exposure. Root canal treatment was performed at the first visit, with crown restoration performed with composite resin. The permanent tooth germ showed the same development as the contralateral one.</div></div><div><h3>Conclusion</h3><div>Symptoms observed in the affected tooth were somewhat similar to those in regional odontodysplasia cases. Careful follow-up examinations until permanent tooth replacement will be necessary.</div></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"35 1","pages":"Article 100332"},"PeriodicalIF":0.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143611199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-04-01Epub Date: 2024-12-14DOI: 10.1016/j.pdj.2024.11.006
Uğur Akdağ , Kamile Nur Tozar
Congenital pain insensitivity syndrome with anhidrosis (CIPA, MIM 256800) or hereditary sensory and autonomic neuropathy (HSAN) type IV is a rare autosomal recessive disease. CIPA has characteristic symptoms such as failure to respond to painful stimuli, lack of thermal sensitivity, decreased or absent sweating (anhidrosis), varying degrees of reduced intellectual disability, musculoskeletal fractures, and joint deformities. A 4-year-old female patient diagnosed with CIPA syndrome presented to our clinic with the complaint of self-harm with her anterior teeth. In the clinical examination, sores were detected on the child's hands, fingers, mouth, and tongue. The front teeth of the patient, which caused the trauma, were extracted. In the 6-month follow-up, the patient's wounds healed. In this case report, the treatment of a patient with CIPA syndrome who was severely self-harming is described.
{"title":"Dental approach to a pediatric patient with congenital insensitivity to pain and anhidrosis (CIPA) syndrome: A case report","authors":"Uğur Akdağ , Kamile Nur Tozar","doi":"10.1016/j.pdj.2024.11.006","DOIUrl":"10.1016/j.pdj.2024.11.006","url":null,"abstract":"<div><div>Congenital pain insensitivity syndrome with anhidrosis (CIPA, MIM <span><span>256800</span><svg><path></path></svg></span>) or hereditary sensory and autonomic neuropathy (HSAN) type IV is a rare autosomal recessive disease. CIPA has characteristic symptoms such as failure to respond to painful stimuli, lack of thermal sensitivity, decreased or absent sweating (anhidrosis), varying degrees of reduced intellectual disability, musculoskeletal fractures, and joint deformities. A 4-year-old female patient diagnosed with CIPA syndrome presented to our clinic with the complaint of self-harm with her anterior teeth. In the clinical examination, sores were detected on the child's hands, fingers, mouth, and tongue. The front teeth of the patient, which caused the trauma, were extracted. In the 6-month follow-up, the patient's wounds healed. In this case report, the treatment of a patient with CIPA syndrome who was severely self-harming is described.</div></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"35 1","pages":"Article 100335"},"PeriodicalIF":0.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143611206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-04-01Epub Date: 2024-11-30DOI: 10.1016/j.pdj.2024.11.004
Ricardo Alves Meireles , José Eugênio Teixeira Rocha , Juliana Ribeiro Francelino Sampaio , Francisco Claudeni Pereira de Sousa , Henrique Douglas Melo Coutinho , Roberto Flávio Fontenelle Pinheiro Júnior
In the type III facial growth pattern, craniofacial disharmony is observed, which may be a maxillary retrusion or mandibular advancement as the most diagnosed postures. This case report aims to report the use of the technique (MAMP) in a patient, who is diagnosed with a growing type III facial and skeletal pattern, as well as its efficacy and adverse effect. For the treatment, the hybrid palatine circuit breaker with mini implants were used, associated with mini mandibular implants, joined by class III elastic. Obtaining satisfactory skeletal result for treatment of pattern III in patients in the final phase of growth.
{"title":"Treatment of pattern III with maxillary protraction supported by mini-implants (MAMP technique)","authors":"Ricardo Alves Meireles , José Eugênio Teixeira Rocha , Juliana Ribeiro Francelino Sampaio , Francisco Claudeni Pereira de Sousa , Henrique Douglas Melo Coutinho , Roberto Flávio Fontenelle Pinheiro Júnior","doi":"10.1016/j.pdj.2024.11.004","DOIUrl":"10.1016/j.pdj.2024.11.004","url":null,"abstract":"<div><div>In the type III facial growth pattern, craniofacial disharmony is observed, which may be a maxillary retrusion or mandibular advancement as the most diagnosed postures. This case report aims to report the use of the technique (MAMP) in a patient, who is diagnosed with a growing type III facial and skeletal pattern, as well as its efficacy and adverse effect. For the treatment, the hybrid palatine circuit breaker with mini implants were used, associated with mini mandibular implants, joined by class III elastic. Obtaining satisfactory skeletal result for treatment of pattern III in patients in the final phase of growth.</div></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"35 1","pages":"Article 100333"},"PeriodicalIF":0.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143611200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-04-01Epub Date: 2025-02-20DOI: 10.1016/j.pdj.2025.100343
Ali Azhar Dawasaz , Dinesh Kumar , Anuj Shukla , Lakshya Raj Khatri , Rafi A. Togoo , Zuliani Mahmood , Ahmad Azlina , Kannan Thirumulu Ponnuraj
Objectives
Salivary proton Nuclear Magnetic Resonance Spectroscopy (1H NMR) has been widely used in metabonomic studies. A research gap still exists in analysing the metabolic profile in obese children suffering from severe dental caries. The aim of this study was to analyse the most identified metabolites in 10–12 years old obese children with severe dental caries and compare them with normal healthy age-matched children.
Materials and methods
Obese children with Body Mass Index Z-score > +2 (n = 20) and normal weight children (control) (n = 20) with severe caries underwent 1.5 mL saliva collection followed by 1H NMR imaging. Spectra were analysed using TopSpin 3.5 and metabolite assignments were made using Chenomx NMR suite and human metabolite database.
Results
A total of 38 common metabolites were identified out of which eight were significantly increased in obese children (p < 0.05). Succinylacetone and glutamine among eight other metabolites significantly increased in the saliva of obese children suffering from severe dental caries. They were also the top contributors in the VIP score plot.
Conclusions
Thirteen (3 amino acids, 4 carboxylic acids, 2 ketoacids, 1 alcohol and 3 miscellaneous metabolites) out of the 38 metabolites identified in normal and obese children with severe dental caries, had high VIP score. Glutamine and succinylacetone showed the highest VIP score with eight metabolites significantly increased in the saliva of obese children.
Clinical relevance
This study could pave way in advancing our understanding of the relationship between caries and obesity and the potential role the metabolites can play in comparison with the normal individuals.
{"title":"Salivary 1H NMR analysis of obese pediatric patients with severe dental caries","authors":"Ali Azhar Dawasaz , Dinesh Kumar , Anuj Shukla , Lakshya Raj Khatri , Rafi A. Togoo , Zuliani Mahmood , Ahmad Azlina , Kannan Thirumulu Ponnuraj","doi":"10.1016/j.pdj.2025.100343","DOIUrl":"10.1016/j.pdj.2025.100343","url":null,"abstract":"<div><h3>Objectives</h3><div>Salivary proton Nuclear Magnetic Resonance Spectroscopy (<sup>1</sup>H NMR) has been widely used in metabonomic studies. A research gap still exists in analysing the metabolic profile in obese children suffering from severe dental caries. The aim of this study was to analyse the most identified metabolites in 10–12 years old obese children with severe dental caries and compare them with normal healthy age-matched children.</div></div><div><h3>Materials and methods</h3><div>Obese children with Body Mass Index Z-score > +2 (<em>n</em> = 20) and normal weight children (control) (<em>n</em> = 20) with severe caries underwent 1.5 mL saliva collection followed by <sup>1</sup>H NMR imaging. Spectra were analysed using TopSpin 3.5 and metabolite assignments were made using Chenomx NMR suite and human metabolite database.</div></div><div><h3>Results</h3><div>A total of 38 common metabolites were identified out of which eight were significantly increased in obese children (p < 0.05). Succinylacetone and glutamine among eight other metabolites significantly increased in the saliva of obese children suffering from severe dental caries. They were also the top contributors in the VIP score plot.</div></div><div><h3>Conclusions</h3><div>Thirteen (3 amino acids, 4 carboxylic acids, 2 ketoacids, 1 alcohol and 3 miscellaneous metabolites) out of the 38 metabolites identified in normal and obese children with severe dental caries, had high VIP score. Glutamine and succinylacetone showed the highest VIP score with eight metabolites significantly increased in the saliva of obese children.</div></div><div><h3>Clinical relevance</h3><div>This study could pave way in advancing our understanding of the relationship between caries and obesity and the potential role the metabolites can play in comparison with the normal individuals.</div></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"35 1","pages":"Article 100343"},"PeriodicalIF":0.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143444732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In Japan, a universal health insurance coverage system has been established, and everyone has equal access to medical care. Therefore, Japan is often considered to have less disparity in living standards than other countries. However, there are few reports on a correlation between social class and health due to the image of fewer individual disparities.
Aim
This study aimed to investigate the association between childhood dental caries and socioeconomic background.
Methods
Using various government statistics sources, we examined the association between childhood dental caries and socioeconomic factors in Japan including the induced abortion rate and number of recognized criminal offenses as objective variables.
Four factors were selected as explanatory variables: monthly income per household, percentage of expenditure on other living expenses, number of penal-code offenses, and clearance rate of penal-code offenses. The induced abortion rates per 1000 women by age for prefectures or induced abortion rates per 1000 women aged 25–29 years for prefectures (‰) were correlated with the prevalence of dental caries in children as explanatory variables.
Results
This study demonstrated a significant effect (p<0.05) of induced abortion on increased childhood dental caries.
Conclusion
Our findings highlight the importance of dentists sharing medical knowledge about obstetrics and pediatrics with the community and other medical professionals through avenues such as community medicine and school health checkups.
{"title":"Relationship between childhood caries and social background: Regarding the novel emerged correlation between induced abortion and dental caries","authors":"Takafumi Nagao , Naoki Nakao , Masataka Nagao , Hiroko Oka , Ayumu Nakashima , Mitsuhiro Uchida , Ayumu Ito , Ryota Nomura , Kazuhiro Shimamura , Akira Namera , Takahiro Harada , Kazuhiro Murata , Kouki Hatori","doi":"10.1016/j.pdj.2025.100341","DOIUrl":"10.1016/j.pdj.2025.100341","url":null,"abstract":"<div><h3>Background</h3><div>In Japan, a universal health insurance coverage system has been established, and everyone has equal access to medical care. Therefore, Japan is often considered to have less disparity in living standards than other countries. However, there are few reports on a correlation between social class and health due to the image of fewer individual disparities.</div></div><div><h3>Aim</h3><div>This study aimed to investigate the association between childhood dental caries and socioeconomic background.</div></div><div><h3>Methods</h3><div>Using various government statistics sources, we examined the association between childhood dental caries and socioeconomic factors in Japan including the induced abortion rate and number of recognized criminal offenses as objective variables.</div><div>Four factors were selected as explanatory variables: monthly income per household, percentage of expenditure on other living expenses, number of penal-code offenses, and clearance rate of penal-code offenses. The induced abortion rates per 1000 women by age for prefectures or induced abortion rates per 1000 women aged 25–29 years for prefectures (‰) were correlated with the prevalence of dental caries in children as explanatory variables.</div></div><div><h3>Results</h3><div>This study demonstrated a significant effect (p<0.05) of induced abortion on increased childhood dental caries.</div></div><div><h3>Conclusion</h3><div>Our findings highlight the importance of dentists sharing medical knowledge about obstetrics and pediatrics with the community and other medical professionals through avenues such as community medicine and school health checkups.</div></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"35 1","pages":"Article 100341"},"PeriodicalIF":0.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143471499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In 2018, disease of developmental insufficiency of oral function (DIOF) was added to the Japanese national dental health insurance for typically developing children. We aimed to confirm the actual number of typically developing children with DIOF using the national database (NDB) and estimate the incidence rate of DIOF among such children.
Methods
The number of children with DIOF was calculated using the NDB in 2020, 2021, and 2022 and activities in the June 2023 of Public Health Insurance. We based the population data on the annual report of single year current population estimates in 2022.
Results
Using the 2022 population data of children aged 0–17 y (17,738,000 children) and the 2022 DIOF patient data, we calculated that the incidence rate was 2431.3/100,000 children (2.4%) in 2022. The number of these children increased each year between June 2020, June 2021, and June 2022; in June 2022, there were almost 1.3 times the number of visits as that in June 2021. There were 130,259 visits based on the estimated DIOF outpatient data in June 2023, 1.1 times that of June 2022.
Conclusion
This study is the first to report the incidence rate of DIOF in typically developing children in Japan. However, we only assessed outpatients; there may be more affected children in Japan. Therefor DIOF examination is a necessary public health approach to support oral function development and to reduce the incidence of DIOF.
{"title":"Number of children with developmental insufficiency of oral function: A study using Japan's national database","authors":"Hiroyuki Yamada , Fumiyo Tamura , Takeshi Kikutani","doi":"10.1016/j.pdj.2024.11.005","DOIUrl":"10.1016/j.pdj.2024.11.005","url":null,"abstract":"<div><h3>Introduction</h3><div>In 2018, disease of developmental insufficiency of oral function (DIOF) was added to the Japanese national dental health insurance for typically developing children. We aimed to confirm the actual number of typically developing children with DIOF using the national database (NDB) and estimate the incidence rate of DIOF among such children.</div></div><div><h3>Methods</h3><div>The number of children with DIOF was calculated using the NDB in 2020, 2021, and 2022 and activities in the June 2023 of Public Health Insurance. We based the population data on the annual report of single year current population estimates in 2022.</div></div><div><h3>Results</h3><div>Using the 2022 population data of children aged 0–17 y (17,738,000 children) and the 2022 DIOF patient data, we calculated that the incidence rate was 2431.3/100,000 children (2.4%) in 2022. The number of these children increased each year between June 2020, June 2021, and June 2022; in June 2022, there were almost 1.3 times the number of visits as that in June 2021. There were 130,259 visits based on the estimated DIOF outpatient data in June 2023, 1.1 times that of June 2022.</div></div><div><h3>Conclusion</h3><div>This study is the first to report the incidence rate of DIOF in typically developing children in Japan. However, we only assessed outpatients; there may be more affected children in Japan. Therefor DIOF examination is a necessary public health approach to support oral function development and to reduce the incidence of DIOF.</div></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"35 1","pages":"Article 100334"},"PeriodicalIF":0.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143611205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
To ensure healthy dental and occlusal development, various space maintainers are used to maintain gap spaces due to the early loss of deciduous teeth.
Case presentation
A W-shaped loop was used to maintain the gap between the extracted mandibular second deciduous molars bilaterally. Space maintenance using the W-shaped loop prevented mesial shift and inclination of the first permanent molars during eruption, and prevented the opposing teeth from overeruption by positioning the wire section parallel to the occlusal plane.
Conclusion
The newly developed W-shaped loop for space maintenance overcomes the disadvantages of distal shoe space maintainers.
{"title":"Space maintenance for early loss of a second deciduous molar using the novel W-type loop","authors":"Issei Saitoh , Yuria Hori , Mie Anayama-Kurosawa , Saeko Tsukuno , Yuki Kiyokawa , Masahiko Terajima","doi":"10.1016/j.pdj.2024.09.002","DOIUrl":"10.1016/j.pdj.2024.09.002","url":null,"abstract":"<div><h3>Background</h3><div>To ensure healthy dental and occlusal development, various space maintainers are used to maintain gap spaces due to the early loss of deciduous teeth.</div></div><div><h3>Case presentation</h3><div>A W-shaped loop was used to maintain the gap between the extracted mandibular second deciduous molars bilaterally. Space maintenance using the W-shaped loop prevented mesial shift and inclination of the first permanent molars during eruption, and prevented the opposing teeth from overeruption by positioning the wire section parallel to the occlusal plane.</div></div><div><h3>Conclusion</h3><div>The newly developed W-shaped loop for space maintenance overcomes the disadvantages of distal shoe space maintainers.</div></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"34 3","pages":"Pages 186-190"},"PeriodicalIF":0.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143146815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-01Epub Date: 2024-11-07DOI: 10.1016/j.pdj.2024.10.004
Risako Kinoshita, Naomi Tanoue
Objective
This study aimed to investigate the factors related to the survival of retained deciduous teeth (RDTs).
Materials and methods
RDTs were identified in panoramic X-ray images in 13,516 patients at Nagasaki University Hospital from 2014 to 2018. The survival status of the RDTs was tracked using medical records; survival rates were calculated. The RDTs were divided into two groups: before and after the completion of stable permanent dentition. A shared frailty analysis was performed in each group, estimating hazard ratios and 95% confidence intervals for variables related to survival.
Results
A total of 138 patients (50 male and 88 female participants, 1.02%) had RDTs. The total number of RDTs was 274, with survival rates of 62.48% at 10 years and 53.30% at 20 years. Before the completion of permanent dentition, the longevity of RDTs was associated with two variables: tooth type (anterior/molar) and presence or absence of successive permanent teeth. No variables were associated with RDT survival after permanent dentition was stabilized.
Conclusion
Multiple congenital factors affect the longevity of RDTs before the stabilization of permanent dentition. However, no significant influence was observed based on factors identified retrospectively after the permanent dentition was stabilized.
{"title":"Longevity of retained deciduous teeth: A retrospective cohort study","authors":"Risako Kinoshita, Naomi Tanoue","doi":"10.1016/j.pdj.2024.10.004","DOIUrl":"10.1016/j.pdj.2024.10.004","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to investigate the factors related to the survival of retained deciduous teeth (RDTs).</div></div><div><h3>Materials and methods</h3><div>RDTs were identified in panoramic X-ray images in 13,516 patients at Nagasaki University Hospital from 2014 to 2018. The survival status of the RDTs was tracked using medical records; survival rates were calculated. The RDTs were divided into two groups: before and after the completion of stable permanent dentition. A shared frailty analysis was performed in each group, estimating hazard ratios and 95% confidence intervals for variables related to survival.</div></div><div><h3>Results</h3><div>A total of 138 patients (50 male and 88 female participants, 1.02%) had RDTs. The total number of RDTs was 274, with survival rates of 62.48% at 10 years and 53.30% at 20 years. Before the completion of permanent dentition, the longevity of RDTs was associated with two variables: tooth type (anterior/molar) and presence or absence of successive permanent teeth. No variables were associated with RDT survival after permanent dentition was stabilized.</div></div><div><h3>Conclusion</h3><div>Multiple congenital factors affect the longevity of RDTs before the stabilization of permanent dentition. However, no significant influence was observed based on factors identified retrospectively after the permanent dentition was stabilized.</div></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"34 3","pages":"Pages 152-157"},"PeriodicalIF":0.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143146810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
扫码关注我们
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号