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Can herbal products be alternative root canal irrigation solutions in primary teeth? An in vitro study 草药产品可以替代乳牙根管冲洗解决方案吗?体外研究
IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2022-12-01 DOI: 10.1016/j.pdj.2022.09.001
Semih Ercan Akgun , Ipek Arslan , Sema Aydinoglu , Dilara Nil Gunacar , Sengul Alpay Karaoglu , Emine Yurteri , Seyma Suyabatmaz

Objectives

To evaluate antimicrobial properties and smear layer removal efficiency of various plant extracts and apple cider vinegar (AV).

Methods

A total of 112 primary molars roots were randomly divided into two groups (n = 56) for antimicrobial test and infected with E faecalis and Candida albicans then divided again into 7 groups (n = 8) as physiological saline (PS), NaOCI, white tea (WT), Helichrysum arenarium (HA), AV, Citrus lemon (CL), and Anzer thyme (AT). Disinfecting abilities were measured with ImageJ. In the smear layer removal efficiency test, prepared 70 roots were divided into 7 groups (n = 10) as in the antimicrobial test also 2 subgroups were designed as with or without EDTA usage (n = 5). All samples were examined under SEM. Open dentin tubule percentage was evaluated with ImageJ.

Results

HA and CL showed higher antibacterial activity against E. faecalis than PS (p = 0.038, p = 0.009) Antifungal activity of AV against C. albicans was higher than saline (p < 0.001). AV in the coronal third and CL in the middle third removed more smear layer than saline and NaOCI (p < 0.05). In the coronal region, HA and AV showed similar smear layer removal efficacy to NaOCl + EDTA (p > 0.05). CL, HA, and AV presented statistically similar results to NaOCl + EDTA in smear layer removal efficacy in the middle region (p > 0.05).

Conclusions

CL and AV have antimicrobial efficacy against E. faecalis and C. albicans respectively and smear layer removal activity.

目的评价不同植物提取物和苹果醋(AV)的抑菌性能和去污效果。方法将112例初磨牙根随机分为2组(n = 56)进行抗菌试验,分别感染粪肠杆菌和白色念珠菌,然后再分为生理盐水(PS)组、NaOCI组、白茶(WT)组、蜡菊(HA)组、AV组、柠檬(CL)组和安泽尔百里香(AT)组7组(n = 8)。用ImageJ测定消毒能力。在涂层去除效率测试中,将制备好的70根与抗菌试验一样分为7组(n = 10),并将2个亚组设计为使用EDTA或不使用EDTA (n = 5)。所有样品在扫描电镜下进行检查。使用ImageJ评估开放牙本质小管百分比。结果杀菌素对粪肠杆菌的抑菌活性明显高于白藜芦醇(p = 0.038, p = 0.009);0.001)。冠状三分之一的AV和中间三分之一的CL比生理盐水和NaOCI去除更多的涂片层(p <0.05)。在冠状区,HA和AV表现出与NaOCl + EDTA相似的涂抹层去除效果(p >0.05)。CL、HA、AV与NaOCl + EDTA在中部涂抹层去除效果上具有统计学上的相似(p >0.05)。结论scl和AV分别对粪肠杆菌和白色念珠菌具有抑菌作用,并具有去除涂片层的活性。
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引用次数: 1
Effects of mouthguard and paste containing S-PRG filler on remineralization of artificial subsurface carious lesions 含S-PRG填料的护齿及膏体对人工牙下龋再矿化的影响
IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2022-12-01 DOI: 10.1016/j.pdj.2022.07.003
Keito Yoshiyasu, Noriko Wakamatsu, Mituo Iinuma, Issei Saitoh

Objectives

The aim of this in vitro study was to evaluate the remineralization effects of ethylene-vinyl acetate (EVA) sheet (sample; SHOFU) and paste (PRG Pro-Care Gel®; SHOFU) containing surface pre-reacted glass-ionomer (S-PRG) filler.

Materials and methods

Extracted human premolars were decalcified to create subsurface carious lesions on the buccal side. Decalcified tooth specimens were then covered by EVA sheets with two different S-PRG filler contents either with application of paste (PRG MG-Paste and EVA MG-Paste groups) or without application of paste (PRG MG and EVA MG groups), then immersed in a remineralization solution. Control group teeth were not covered with any mouthguard and did not receive application of paste. Micro-CT (μCT) images of the teeth before and after the remineralization process were obtained to compare mineral gains. The percentage remineralization (%R) of each group was calculated using the mineral density (MD) profile from μCT. The microstructure of the tooth surface was observed under scanning electron microscopy, and constituent elements were examined using an electron probe micro-analyzer.

Results

The PRG MG group showed a significantly higher %R than the Control or EVA MG groups. The PRG MG-Paste group showed a significantly higher %R than the PRG MG group. In the PRG MG-Paste group, small precipitations were observed on tooth surface, and silica and aluminum were detected.

Conclusion

The combination use of S-PRG filler containing EVA sheet and PRG Pro-Care Gel exhibits a synergetic effect on remineralization of pre-cavitation carious lesions.

目的探讨醋酸乙烯(EVA)片材(样品)的再矿化作用;SHOFU)和膏体(PRG Pro-Care Gel®;含有表面预反应玻璃离子(S-PRG)填料的SHOFU。材料与方法将拔除的人前磨牙进行脱钙处理,在颊侧形成表面下龋齿。将脱钙牙标本覆盖在含有两种不同S-PRG填充物含量的EVA片上,涂上膏体(PRG MG- paste组和EVA MG- paste组)或不涂膏体(PRG MG组和EVA MG组),然后浸入再矿化溶液中。对照组不涂护齿,不涂膏。对再矿化前后牙齿的微ct (μCT)图像进行比较。利用μCT的矿物密度(MD)谱计算各组再矿化率(%R)。采用扫描电子显微镜观察齿面显微组织,并用电子探针微量分析仪检测其组成元素。结果PRG MG组的%R显著高于对照组和EVA MG组。PRG MG- paste组的%R显著高于PRG MG组。PRG MG-Paste组牙面有少量沉淀,并检测到二氧化硅和铝。结论含EVA片的S-PRG填充剂与PRG Pro-Care凝胶联合使用对预空化龋齿的再矿化具有协同作用。
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引用次数: 1
Evaluation of remineralizing potential of hydroxyapatite, phosphopeptide-amorphous calcium phospahate and fluoride dentifrices using SEM/EDX analysis: A randomized controlled in-vitro study 利用扫描电镜/EDX分析评价羟基磷灰石、磷酸肽-无定形磷酸钙和氟化物牙膏的再矿化潜力:一项随机对照体外研究
IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2022-12-01 DOI: 10.1016/j.pdj.2022.07.001
Elis Mutlu , Mikail Ozdemir , Koray Gencay

Aim

The aim of this study is to evaluate remineralization efficiency of hydroxyapatite (HA) containing dentifrices comparing to phosphopeptide-amorphous calcium phosphate (CPP-ACP) and fluoride (F) containing dentifrices using scanning electron microscope (SEM) and energy dispersive spectrometry (SEM/EDX).

Material and methods

3 × 3 mm2 areas on the buccal surfaces of extracted primary second molars were divided vertically into 3 sections as demineralization, control and remineralization surfaces. Control surfaces (1/3 middle) coated without any application. 1/3 left and right surfaces were subjected to demineralization solution. After this application 1/3 right surfaces were coated as demineralization surfaces. Then teeth were randomly separated in 3 groups (n = 10): group HA (Natural toothpaste, Splat®, Russia); Group CPP-ACP (MI Paste ONE®, GC, U.S.); group F (Oral-B® Kids, Oral-B, Germany). 1/3 right surfaces were brushed with dentifrices twice a day for one week with pH cycle. Coatings were removed. Surface evaluations were conducted by SEM and EDX. Mann Whitney U and Kruskal Wallis tests were used for statistical analysis.

Results

Both atomic (at%) and weight (wt%) percentages of P values were statistically significant for F group in remineralization surfaces comparing to demineralization surfaces. Ca at%, P at% and P wt% values were statistically significant for CPP-ACP group in remineralization surfaces. P at% and P wt% values for F group were higher in remineralization surfaces compared to all.

Conclusion

Remineralization was observed in all groups. Most homogeneous surface features were seen in group CPP-ACP.

目的利用扫描电镜(SEM)和能谱分析(SEM/EDX)技术,比较含磷磷灰石(HA)与磷酸肽-无定形磷酸钙(CPP-ACP)和含氟磷灰石(F)的再矿化效果。材料与方法将拔除的第二磨牙颊面3 × 3 mm2的面积垂直分为脱矿面、控制面和再矿面3个断面。控制面(中间1/3)无任何涂抹。1/3左右表面用脱矿液处理。在此应用后,1/3的右表面涂覆作为脱矿表面。将牙齿随机分为3组(n = 10): HA组(天然牙膏,Splat®,俄罗斯);pcp - acp (MI Paste ONE®,GC,美国);F组(Oral-B®Kids, Oral-B,德国)。1/3右侧表面用牙刷洗,每天两次,连续一周。涂层被去除。通过SEM和EDX进行表面评价。采用Mann Whitney U和Kruskal Wallis检验进行统计分析。结果与脱矿表面相比,F组再矿表面P值的原子百分比(at%)和重量百分比(wt%)均有统计学意义。CPP-ACP组再矿化表面Ca at%、P at%、P wt%值均有统计学意义。F组再矿化表面的P at%和P wt%值高于所有组。结论各组均存在再矿化现象。pcp - acp组的表面特征最均匀。
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引用次数: 0
Occurrence of subcutaneous emphysema during a caries filling procedure: A case report 龋充填过程中皮下肺气肿的发生:1例报告
IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2022-12-01 DOI: 10.1016/j.pdj.2022.06.002
Takashi Kikuiri , Kureha Saito , Airi Iida , Yoshitaka Yoshimura , Yasutaka Yawaka , Tetsuo Shirakawa

Subcutaneous emphysema can occur during dental treatment. In this study, we describe a rare case in which subcutaneous emphysema has developed and extended to the sternum during the filling of a mandibular second molar in a 14-year-old girl. The patient was hospitalized immediately to prevent infection and was discharged 4 days later without infection or other complications. Subcutaneous emphysema extending to the sternum rarely occurs during routine dental procedures such as filling teeth. However, enlargement of subcutaneous emphysema can lead to fatal complications such as pneumothorax, cardiac tamponade, tracheal compression, and mediastinitis. Serious risks are associated with inducing subcutaneous emphysema, and appropriate care is necessary immediately after its onset.

在牙科治疗期间可发生皮下肺气肿。在这项研究中,我们描述了一个罕见的情况下,皮下肺气肿已经发展并扩展到胸骨在填充下颌第二磨牙在14岁的女孩。患者立即住院预防感染,4天后出院,无感染及其他并发症。皮下肺气肿延伸到胸骨很少发生在常规牙科手术,如补牙。然而,皮下肺气肿的扩大可导致致命的并发症,如气胸、心脏填塞、气管压迫和纵隔炎。严重的风险与诱发皮下肺气肿有关,发病后立即进行适当的护理是必要的。
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引用次数: 1
Can dentists contribute to early screening for developmental disorders in five-year-old children during health checkups? 牙医能否协助五岁儿童在健康检查时及早筛检发育障碍?
IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2022-12-01 DOI: 10.1016/j.pdj.2022.06.001
Toshiyuki Yoneyama , Akemi Utsumi , Akiko Ishizaki , Mari Takahashi , Satoko Yamaguchi , Takuya Asami , Shouji Hironaka

Aim

This study aimed to clarify the relationship between developmental disorders and oral function assessed using the mouth rinsing function test (MRFT).

Materials and methods

A total of 1147 children who underwent health checkups between 2014 and 2017 were included. We divided the patients into two groups based on their MRFT findings: good and poor oral function. We analyzed the associations between the outcomes of MRFT and other assessments using the chi-squared test and multiple variable logistic regression analysis.

Results

Of the 1147 participants, 346 (30.2%) were suspected of having developmental disorders, 951 (82.9%) had good oral function, and 196 (17.1%) had poor oral function. Statistical analysis demonstrated significant differences in developmental disorders and oral function. Children suspected of having developmental disorders had significantly poor oral function.

Conclusions

Dentists can detect early signs of developmental disorders using MRFT owing to its convenient performed in dental clinics. Developmental disorders possess spectrums of symptoms and various accompanying conditions; therefore, collaboration with other professionals is crucial for early screening and child support during their development.

目的利用口腔冲洗功能测试(MRFT)评估发育障碍与口腔功能之间的关系。材料与方法纳入2014 - 2017年间接受健康检查的1147名儿童。我们根据MRFT结果将患者分为两组:口腔功能良好和较差。我们使用卡方检验和多变量logistic回归分析来分析MRFT结果与其他评估结果之间的关联。结果1147例患者中,有发育障碍的346例(30.2%),口腔功能良好的951例(82.9%),口腔功能差的196例(17.1%)。统计分析显示发育障碍和口腔功能有显著差异。怀疑有发育障碍的儿童,其口腔功能明显较差。结论磁共振成像技术可方便地在牙科诊所发现发育障碍的早期症状。发育障碍具有一系列症状和各种伴随条件;因此,与其他专业人员合作对于早期筛查和儿童发育期间的支持至关重要。
{"title":"Can dentists contribute to early screening for developmental disorders in five-year-old children during health checkups?","authors":"Toshiyuki Yoneyama ,&nbsp;Akemi Utsumi ,&nbsp;Akiko Ishizaki ,&nbsp;Mari Takahashi ,&nbsp;Satoko Yamaguchi ,&nbsp;Takuya Asami ,&nbsp;Shouji Hironaka","doi":"10.1016/j.pdj.2022.06.001","DOIUrl":"10.1016/j.pdj.2022.06.001","url":null,"abstract":"<div><h3>Aim</h3><p>This study aimed to clarify the relationship between developmental disorders and oral function assessed using the mouth rinsing function test (MRFT).</p></div><div><h3>Materials and methods</h3><p>A total of 1147 children who underwent health checkups between 2014 and 2017 were included. We divided the patients into two groups based on their MRFT findings: good and poor oral function. We analyzed the associations between the outcomes of MRFT and other assessments using the chi-squared test and multiple variable logistic regression analysis.</p></div><div><h3>Results</h3><p>Of the 1147 participants, 346 (30.2%) were suspected of having developmental disorders, 951 (82.9%) had good oral function, and 196 (17.1%) had poor oral function. Statistical analysis demonstrated significant differences in developmental disorders and oral function. Children suspected of having developmental disorders had significantly poor oral function.</p></div><div><h3>Conclusions</h3><p>Dentists can detect early signs of developmental disorders using MRFT owing to its convenient performed in dental clinics. Developmental disorders possess spectrums of symptoms and various accompanying conditions; therefore, collaboration with other professionals is crucial for early screening and child support during their development.</p></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"32 3","pages":"Pages 141-150"},"PeriodicalIF":0.8,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0917239422000222/pdfft?md5=11cc1dc652ea17ffd6a6662762f9bc95&pid=1-s2.0-S0917239422000222-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44690467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Association of MMP9, MMP13 and MMP20 genes polymorphism with dental caries: A meta-analysis MMP9、MMP13和MMP20基因多态性与龋病的关联:一项荟萃分析
IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2022-12-01 DOI: 10.1016/j.pdj.2022.09.002
Zahra Molaei , Paria Motahari

Objectives

Genetic factors can be involved in dental caries as the most common chronic oral diseases. The association between polymorphism of MMP9, MMP13 and MMP20 genes with tooth decay has been studied but contradictory outcomes have been indicated. Thus, a meta-analysis was done to get comprehensive outcomes in this path.

Materials and methods

All articles in English by March 2022 were searched with correlated keywords from known database as PubMed, Scopus, Embase and Web of Science, and the articles were selected in several stages based on exclusion and inclusion criteria. Comprehensive meta-analysis software v.2.0 was used for Meta-analysis.

Results

Finally, 11 related articles were selected for meta-analysis. According to the results, MMP9 and MMP20 polymorphisms were not related with increased susceptibility to caries in the studied models, but in the case of MMP13, a significant association was observed between gene polymorphism and caries risk.

Conclusion

The results about MMP13 gene polymorphism showed that guanine G allele and GG genotype have a protective role and decrease the risk of dental caries. It should be noted that, these conclusions could be promoted by studies contain large sample sizes. Finding the genetic factors influencing tooth decay can help increase our current knowledge of caries pathology, predict its occurrence, and target genes at the molecular level to prevent it.

目的龋病是口腔最常见的慢性疾病,与遗传因素有关。MMP9、MMP13和MMP20基因多态性与蛀牙之间的关系已被研究,但结果却相互矛盾。因此,我们进行了一项荟萃分析,以获得这一途径的综合结果。材料与方法采用相关关键词检索PubMed、Scopus、Embase、Web of Science等数据库中截至2022年3月的所有英文论文,根据排除和纳入标准分阶段筛选。采用综合meta分析软件v.2.0进行meta分析。结果最终选取11篇相关文献进行meta分析。结果显示,在所研究的模型中,MMP9和MMP20基因多态性与龋病易感性增加无关,但在MMP13基因多态性中,基因多态性与龋病风险显著相关。结论MMP13基因多态性分析结果表明,鸟嘌呤G等位基因和GG基因型对龋病有保护作用,可降低龋病发生风险。值得注意的是,这些结论可以通过包含大样本量的研究来促进。发现影响蛀牙的遗传因素可以帮助我们增加对龋齿病理的现有知识,预测其发生,并在分子水平上靶向基因来预防龋齿。
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引用次数: 0
LARAGA – Pharmacological behaviour management in paediatric dentistry in the UK 英国儿科牙科的药理学行为管理
IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2022-08-01 DOI: 10.1016/j.pdj.2022.04.002
Christopher C. Donnell , Thomas Flavell , Katherine E. Wilson

Introduction

While non-pharmacological behaviour management plays an important role in paediatric dentistry, it is not the solution for all children and a proportion will still require an adjunctive pharmacological approach such as local anaesthetic, relative analgesia or general anaesthetic (LA-RA-GA).

Aims

Paediatric conscious sedation at Newcastle Dental Hospital (NDH) is distinctive in that RA is provided by both the Child Dental Health (CDH) and Sedation (SED) departments. The primary aim of this study was to evaluate the outcomes of the NDH paediatric sedation service and analyse the effect of various confounding factors involved in treatment.

Materials and methods

This cross-sectional analysis forms part of a retrospective service evaluation of the inhalation sedation service provided by Newcastle Dental Hospital. Anonymised data were collected on 200 patients attending NDH (100 CDH, 100 SED) between September 2019 and March 2020. Data were cleaned manually and analysed using descriptive statistics, exploratory analysis with chi-squared tests and multivariable analyses (logistic regression) to identify any factors associated with failed RA appointments.

Results

Overall success for the NDH paediatric inhalation sedation service was 90.5%; CDH %/n = 89%, SED %/n = 92. There was a significant association between a failed RA appointment and no RA experience, a mother attending as chaperone and patients being under six years old. The odds of failure in an afternoon appointment were 1.6 times higher than a morning appointment, and girls were 1.5 times more likely than boys to have a failed RA appointment.

Conclusion

Dental treatment under combined RA and LA is a successful technique for managing mild-to-moderately anxious paediatric patients. Careful patient selection, based on patient cooperation at the initial consultation, alongside an episode of acclimatisation, may help increase treatment success rates.

虽然非药物行为管理在儿科牙科中起着重要作用,但它并不是所有儿童的解决方案,一部分儿童仍然需要辅助的药物方法,如局部麻醉、相对镇痛或全身麻醉(LA-RA-GA)。目的纽卡斯尔牙科医院(NDH)的儿科有意识镇静的独特之处在于,RA是由儿童牙科健康(CDH)和镇静(SED)部门提供的。本研究的主要目的是评估NDH儿科镇静服务的结果,并分析治疗中涉及的各种混杂因素的影响。材料和方法本横断面分析是对纽卡斯尔牙科医院提供的吸入镇静服务进行回顾性服务评估的一部分。在2019年9月至2020年3月期间,收集了200名NDH患者(100名CDH, 100名SED)的匿名数据。手动清理数据,并使用描述性统计、卡方检验的探索性分析和多变量分析(逻辑回归)进行分析,以确定与RA预约失败相关的任何因素。结果NDH患儿吸入性镇静服务总体成功率为90.5%;CDH %/n = 89%, SED %/n = 92。失败的类风湿关节炎预约与没有类风湿关节炎经验、母亲陪同就诊以及患者年龄小于6岁之间存在显著关联。下午预约失败的几率是上午预约的1.6倍,女孩预约失败的几率是男孩的1.5倍。结论RA与LA联合治疗是治疗小儿轻中度焦虑患者的有效方法。在初次会诊时,基于患者的配合和适应情况,仔细选择患者,可能有助于提高治疗成功率。
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引用次数: 2
Effect of different etching time on etch pattern and etch depth using 1% phytic acid in primary teeth – A Scanning Electron Microscopic study 1%植酸对乳牙不同刻蚀时间对刻蚀模式和刻蚀深度的影响——扫描电镜研究
IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2022-08-01 DOI: 10.1016/j.pdj.2022.03.002
D. Ishwarya, A. Victor Samuel, Ramar Kavitha

Objective

This study aimed to evaluate the effect of varied etching time on etch pattern and etch depth with 1% phytic acid in primary teeth.

Materials and methods

Thirty extracted human non-carious primary tooth crowns were sectioned and varnished leaving 4 mm enamel window on buccal surfaces. The teeth were then divided into 3 groups corresponding to etching time 15, 30 and 60 seconds to estimate etch pattern and depth. One percent phytic acid is used for etching the enamel surfaces. The etch pattern and etch depth was observed using Scanning Electron Microscopy (SEM).

Results

The results demonstrated, no differences in etch patterns in all 3 groups irrespective of etch time. Etch depth on enamel surfaces after etching for 15 seconds (group I) and 30 seconds (group II) were similar, but a greater increase in etch depth were observed after 60 seconds (group III) of etching.

Conclusion

One percent phytic acid produced 3 types of etch patterns, among which hollowing of prism core with relatively intact peripheral region etch pattern were predominant irrespective of varying etch time. Etch depth on enamel surfaces increased with increase in etching time.

目的研究1%植酸对乳牙不同时间的腐蚀模式和深度的影响。材料与方法:将30个拔除的人无龋初级牙冠切片,在口腔表面留下4mm的釉质窗口。然后根据腐蚀时间15、30和60秒分为3组,评估腐蚀模式和深度。百分之一的植酸被用来蚀刻牙釉质表面。利用扫描电子显微镜(SEM)观察了刻蚀模式和刻蚀深度。结果结果显示,与蚀刻时间无关,三组的蚀刻图案无差异。蚀刻15秒(第一组)和30秒(第二组)后牙釉质表面的蚀刻深度相似,但蚀刻60秒(第三组)后的蚀刻深度增加更大。结论1%植酸在不同蚀刻时间下,产生3种蚀刻模式,其中以棱柱芯空化为主,外围区域蚀刻模式相对完整。随着蚀刻时间的增加,釉质表面的蚀刻深度增加。
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引用次数: 0
Variability of dental abnormalities according to the timing of anticancer therapy: A report of two cases 根据抗癌治疗时间变化的牙齿异常:附两例报告
IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2022-08-01 DOI: 10.1016/j.pdj.2022.03.001
Gimin Kim, Jaesik Lee

Background

Current multimodality therapies have increased the survival of patients with childhood cancer. However, these therapies increase the risk of dental complications.

Case report

The first case was a 7-year-old girl who was diagnosed with leukemia at around 8 months of age and received anticancer therapy for about 1 year. The second case was an 8-year-old boy who was diagnosed with leukemia at around the age of 6 and received anticancer therapy for about 2 years. Based on long-term follow-up of two cases, tooth agenesis and microdontia occurs when anticancer therapy is performed at the initial stage of tooth development. However shortening roots of the affected teeth can be found when it is performed at the late stage of tooth development.

Conclusions

Early diagnosis and understanding of dental developmental defects resulting from anticancer therapy are essential for preventing tooth loss and space-related problems in the oral cavity.

目前的多模式治疗提高了儿童癌症患者的生存率。然而,这些疗法增加了牙齿并发症的风险。第一个病例是一个7岁的女孩,她在大约8个月大的时候被诊断出患有白血病,并接受了大约1年的抗癌治疗。第二个病例是一个8岁的男孩,他在6岁左右被诊断出患有白血病,接受了大约2年的抗癌治疗。通过对2例患者的长期随访,发现在牙齿发育初期进行抗癌治疗,出现了牙齿发育不全和小牙畸形。然而,当在牙齿发育的后期进行时,可以发现受影响牙齿的根变短。结论早期诊断和了解肿瘤治疗引起的牙齿发育缺陷,对预防牙齿脱落和与口腔空间相关的问题至关重要。
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引用次数: 0
Age estimation of Iraqi children and young adults based on third molar development and its relation to chronological age 基于第三磨牙发育及其与实足年龄关系的伊拉克儿童和青年年龄估计
IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2022-08-01 DOI: 10.1016/j.pdj.2022.02.003
Ayam Taha , Shamam Yousif

Objectives

The study aimed to estimate the age of Iraqi children and young adults based on the third molar development to establish Iraqi reference material for orthodontic and forensic purposes, and to investigate the correlation between the estimated and chronological age.

Methods

A retrospective analysis of digital orthopantographs of 1515 patients of Iraqi origin, aged from 6 to 25 years was conducted, and the developmental status of the mandibular right third molar for each patient was evaluated using Demirjian et al.’s method. Statistical analysis was carried out using “Mann-Whitney U-test” between genders. The linear regression analysis was performed to obtain “regression formulas” for dental age calculation with chronologic age.

Results

No statistically significant differences were observed between Iraqi males and females at any age. The median of male and female age of initial calcification of the cuspal tips for mandibular third molars was 9 years, whereas 14 years was the median of age for both genders when the crown was completed. All mandibular right third molars have a complete root formation with apex closure at a median of male and female age 22 years.

Conclusions

The use of Demirjian et al.’s method was appropriate as a reliable age indicator for Iraqi population. A strong correlation was observed between these stages and chronological age. Consequently, reference data have been established for mandibular third molar development in Iraqi population.

目的根据第三磨牙发育情况估计伊拉克儿童和年轻人的年龄,为正畸和司法鉴定提供参考资料,并探讨估计年龄与实足年龄之间的相关性。方法回顾性分析1515例年龄在6 ~ 25岁的伊拉克裔患者的数字矫形片,采用Demirjian等人的方法评估每位患者下颌右第三磨牙的发育状况。性别间采用“Mann-Whitney u检验”进行统计分析。通过线性回归分析,得到牙龄随年龄计算的“回归公式”。结果伊拉克男性和女性在任何年龄段之间均无统计学差异。男性和女性下颌第三磨牙尖尖初始钙化的年龄中位数为9岁,而冠完成时男女的年龄中位数为14岁。所有的下颌右第三磨牙都有完整的根形成,顶端闭合,平均年龄为22岁。结论Demirjian等人的方法可作为伊拉克人口的可靠年龄指标。在这些阶段和实际年龄之间观察到很强的相关性。因此,建立了伊拉克人口下颌第三磨牙发育的参考数据。
{"title":"Age estimation of Iraqi children and young adults based on third molar development and its relation to chronological age","authors":"Ayam Taha ,&nbsp;Shamam Yousif","doi":"10.1016/j.pdj.2022.02.003","DOIUrl":"10.1016/j.pdj.2022.02.003","url":null,"abstract":"<div><h3>Objectives</h3><p><span>The study aimed to estimate the age of Iraqi children and young adults based on the third molar development to establish Iraqi reference material for </span>orthodontic and forensic purposes, and to investigate the correlation between the estimated and chronological age.</p></div><div><h3>Methods</h3><p>A retrospective analysis of digital orthopantographs of 1515 patients of Iraqi origin, aged from 6 to 25 years was conducted, and the developmental status of the mandibular right third molar for each patient was evaluated using Demirjian et al.’s method. Statistical analysis was carried out using “Mann-Whitney <em>U</em><span>-test” between genders. The linear regression analysis was performed to obtain “regression formulas” for dental age calculation with chronologic age.</span></p></div><div><h3>Results</h3><p>No statistically significant differences were observed between Iraqi males and females at any age. The median of male and female age of initial calcification of the cuspal tips for mandibular third molars was 9 years, whereas 14 years was the median of age for both genders when the crown was completed. All mandibular right third molars have a complete root formation with apex closure at a median of male and female age 22 years.</p></div><div><h3>Conclusions</h3><p>The use of Demirjian et al.’s method was appropriate as a reliable age indicator for Iraqi population. A strong correlation was observed between these stages and chronological age. Consequently, reference data have been established for mandibular third molar development in Iraqi population.</p></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"32 2","pages":"Pages 87-93"},"PeriodicalIF":0.8,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43412428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Pediatric Dental Journal
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