Pub Date : 2024-01-03DOI: 10.1016/j.pdj.2023.12.005
Serap Keskin Tunç , Nihat Efe , Ümit Ertaş
Central giant cell granulomas (CGCGs) of the jaw are benign intraosseous and osteolytic lesions. Their clinical presentation includes atypical aggressive lesions that cause severe damage early in life, and aggressive treatment is necessary in most cases to prevent recurrence. Curettage is the most preferred therapy, but in recent years, conservative therapy is also commonly used. Corticosteroid injection treatment, a conservative method, was planned for a developing male patient with difficulty in diagnosis and treatment due to the complications of resection. After clinical and radiologic evaluation of the patient, incisional biopsy was performed and the diagnosis of SDHG was made. The patient was treated with intralesional corticosteroids once a week for eight weeks. Since the patient's treatment was interrupted for 2 months due to the Covid-19 outbreak, 2 doses of intralesional corticosteroid (Sinakort-A 40 mg) were administered and the patient was followed up. At 12 months, clinical and panoramic radiographic examination revealed no pathologic findings related to the lesion. In this article, we report a pediatric case of giant CGCG successfully treated with intralesional corticosteroid injection.
{"title":"Corticosteroid injection in the treatment of a huge-size central giant cell granuloma in children: A case report","authors":"Serap Keskin Tunç , Nihat Efe , Ümit Ertaş","doi":"10.1016/j.pdj.2023.12.005","DOIUrl":"10.1016/j.pdj.2023.12.005","url":null,"abstract":"<div><p><span><span>Central giant cell granulomas (CGCGs) of the jaw are benign intraosseous and </span>osteolytic lesions<span>. Their clinical presentation includes atypical aggressive lesions that cause severe damage early in life, and aggressive treatment is necessary in most cases to prevent recurrence. </span></span>Curettage<span><span> is the most preferred therapy, but in recent years, conservative therapy is also commonly used. Corticosteroid injection treatment, a conservative method, was planned for a developing male patient with difficulty in diagnosis and treatment due to the complications of resection. After clinical and radiologic evaluation of the patient, incisional biopsy was performed and the diagnosis of SDHG was made. The patient was treated with intralesional corticosteroids once a week for eight weeks. Since the patient's treatment was interrupted for 2 months due to the Covid-19 outbreak, 2 doses of intralesional corticosteroid (Sinakort-A 40 mg) were administered and the patient was followed up. At 12 months, clinical and panoramic radiographic examination revealed no pathologic findings related to the lesion. In this article, we report a </span>pediatric case of giant CGCG successfully treated with intralesional corticosteroid injection.</span></p></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"34 1","pages":"Pages 49-54"},"PeriodicalIF":0.8,"publicationDate":"2024-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139454732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study investigated the association between nasal obstruction and its associated factors in young children by quantitatively measuring the nasal airway resistance (NAR).
Methods
A total of 82 children aged 3–6 years (31 boys and 51 girls) were included in the study. Questionnaires were used to collect information about allergies, nasal diseases, stuffy nose, oral habits, and feeding behavior problems from the parents. Furthermore, measurements of the height, body weight, calf circumference, grip strength, tongue pressure, occlusal force, lip-closure strength, mouth rinsing function test, and NAR were taken.
Results
The NAR was negatively correlated with the height and age of the children. Additionally, NAR was associated with feeding behavior problems, as reported by the parents of the children.
Conclusion
The findings of this study suggest that interviewing parents about their children's feeding behavior problems may prove valuable in diagnosing nasal disorders in young children. Early improvements in nasal obstruction may address feeding behavior problems and contribute to the normal growth and development of oral functions in young children.
{"title":"Factors associated with nasal airway resistance in young children","authors":"Yoshikuni Fujiwara , Shouji Hironaka , Akiko Ishizaki , Satoko Yamaguchi , Akemi Utsumi , Chihiro Ota , Risa Ikeda","doi":"10.1016/j.pdj.2023.12.002","DOIUrl":"10.1016/j.pdj.2023.12.002","url":null,"abstract":"<div><h3>Aim</h3><p>This study investigated the association between nasal obstruction and its associated factors in young children by quantitatively measuring the nasal airway resistance (NAR).</p></div><div><h3>Methods</h3><p>A total of 82 children aged 3–6 years (31 boys and 51 girls) were included in the study. Questionnaires were used to collect information about allergies, nasal diseases, stuffy nose, oral habits, and feeding behavior problems from the parents. Furthermore, measurements of the height, body weight, calf circumference, grip strength, tongue pressure, occlusal force, lip-closure strength, mouth rinsing function test, and NAR were taken.</p></div><div><h3>Results</h3><p>The NAR was negatively correlated with the height and age of the children. Additionally, NAR was associated with feeding behavior problems, as reported by the parents of the children.</p></div><div><h3>Conclusion</h3><p>The findings of this study suggest that interviewing parents about their children's feeding behavior problems may prove valuable in diagnosing nasal disorders in young children. Early improvements in nasal obstruction may address feeding behavior problems and contribute to the normal growth and development of oral functions in young children.</p></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"34 1","pages":"Pages 8-13"},"PeriodicalIF":0.8,"publicationDate":"2023-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0917239423000599/pdfft?md5=130557e5de086e30997f8233b7bcb4e5&pid=1-s2.0-S0917239423000599-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138993306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-22DOI: 10.1016/j.pdj.2023.12.001
Yukina Ota , Tatsuro Ito , Momoko Sashida , Eiji Hori , Manami Kimijima , Naoki Narisawa , Osamu Tsuzukibashi , Takehiko Shimizu
Introduction
The possible association between Candida carriage in children and childhood caries has not been elucidated in the Japanese population. This study aimed to investigate the prevalence, maternal relatedness, and genotypic distribution of Candida albicans in this population.
Materials and methods
We collected dental plaque samples from 55 mother-child pairs in the Caries group and 25 pairs in the caries-free (CF) group to analyze microbial data (carriage and viable counts), focusing on Streptococcus mutans and C. albicans. Clinically isolated 118 Candida strains were further evaluated using arbitrarily primed polymerase chain reaction.
Results
A higher C. albicans carriage rate was observed in the Caries pairs (25.5 % in children, 47.3 % in mothers) than in CF pairs (0 % in children, 24.0 % in mothers). The viable counts of S. mutans were significantly higher in the Caries group than in the CF group (p < 0.05). In addition, S. mutans counts positively correlated with C. albicans counts in the dental plaque of caries-affected children (r = 0.549). Almost all Candida-positive children (92.9 %) were diagnosed with severe early childhood caries, and 79.7 % of Candida isolates from the mother-child pairs were similar at the strain level. C. albicans genotype A was the most predominant (70.6 %) strain, followed by genotype D (17.6 %) in dental plaques from children in the Caries group.
Conclusions
The presence of C. albicans is a risk factor for childhood caries in a Japanese population. Our findings provide new insights into maternal-child oral health instructions based on microbial factors associated with dental caries.
{"title":"Association between Candida albicans and childhood dental caries in Japanese children","authors":"Yukina Ota , Tatsuro Ito , Momoko Sashida , Eiji Hori , Manami Kimijima , Naoki Narisawa , Osamu Tsuzukibashi , Takehiko Shimizu","doi":"10.1016/j.pdj.2023.12.001","DOIUrl":"10.1016/j.pdj.2023.12.001","url":null,"abstract":"<div><h3>Introduction</h3><p>The possible association between <em>Candida</em> carriage in children and childhood caries has not been elucidated in the Japanese population. This study aimed to investigate the prevalence, maternal relatedness, and genotypic distribution of <em>Candida albicans</em> in this population.</p></div><div><h3>Materials and methods</h3><p><span>We collected dental plaque samples from 55 mother-child pairs in the Caries group and 25 pairs in the caries-free (CF) group to analyze microbial data (carriage and viable counts), focusing on </span><span><em>Streptococcus </em><em>mutans</em></span> and <em>C</em>. <em>albicans</em>. Clinically isolated 118 <em>Candida</em><span> strains were further evaluated using arbitrarily primed polymerase chain reaction.</span></p></div><div><h3>Results</h3><p>A higher <em>C</em>. <em>albicans</em> carriage rate was observed in the Caries pairs (25.5 % in children, 47.3 % in mothers) than in CF pairs (0 % in children, 24.0 % in mothers). The viable counts of <em>S</em>. <em>mutans</em> were significantly higher in the Caries group than in the CF group (<em>p</em> < 0.05). In addition, <em>S</em>. <em>mutans</em> counts positively correlated with <em>C</em>. <em>albicans</em> counts in the dental plaque of caries-affected children (r = 0.549). Almost all <em>Candida</em>-positive children (92.9 %) were diagnosed with severe early childhood caries, and 79.7 % of <em>Candida</em> isolates from the mother-child pairs were similar at the strain level. <em>C</em>. <em>albicans</em> genotype A was the most predominant (70.6 %) strain, followed by genotype D (17.6 %) in dental plaques from children in the Caries group.</p></div><div><h3>Conclusions</h3><p>The presence of <em>C</em>. <em>albicans</em> is a risk factor for childhood caries in a Japanese population. Our findings provide new insights into maternal-child oral health instructions based on microbial factors associated with dental caries.</p></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"34 1","pages":"Pages 1-7"},"PeriodicalIF":0.8,"publicationDate":"2023-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139026097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-21DOI: 10.1016/j.pdj.2023.12.004
Ahmad Abdel Hamid Elheeny , Dania Ibrahem Sermani
Aim
The trial aimed to compare the gingival health and clinical performance of prefabricated zirconia crown (PZC) versus resin-bonded composite strip crowns (RCSC) in the restoration of primary maxillary incisors over 36-month.
Materials and methods
A parallel randomized controlled trial included 200 maxillary primary incisors (100 teeth per group) restored either with PZCs or RSCS. The gingival health and plaque accumulation were assessed using gingival index (GI) and plaque index (PI) respectively. To evaluate the clinical performance, the modified United States Public Health Service (USPHS) criteria were used. Intergroup comparison was performed using a Chi-square test. Restoration longevity was assessed over the predetermined intervals using Kaplan-Meier analysis. Generalized Estimating Equation (GEE) with robust standard errors was used to test the effect of time over the changes of repeated measures. The significance level was set to 5%.
Results
The gingival health around PZCs is significantly better than that of RCSCs after 6 months. However, at the following follow-ups, GI scores of both restorations were comparable (p > 0.05). All PZCs showed no plaque accumulation with a significant difference compared to the RCSCs over the follow-up intervals. The clinical performance of PZCs was significantly superior to that of RCSCs over the follow-ups in terms of retention and anatomical contour after 24 and 36 months. The survival rates of PZC and RCSC were 100% and 87% respectively.
Conclusions
After 36 months, the gingival health of PZC and RCSC was comparable. The retention and anatomical continuity of PZC were superior compared to RCSC.
{"title":"Prefabricated zirconia crown versus resin-bonded composite strip crown in the restoration of primary incisors: A 36-month parallel randomized controlled trial","authors":"Ahmad Abdel Hamid Elheeny , Dania Ibrahem Sermani","doi":"10.1016/j.pdj.2023.12.004","DOIUrl":"10.1016/j.pdj.2023.12.004","url":null,"abstract":"<div><h3>Aim</h3><p>The trial aimed to compare the gingival health and clinical performance of prefabricated zirconia<span> crown (PZC) versus resin-bonded composite strip crowns (RCSC) in the restoration of primary maxillary incisors over 36-month.</span></p></div><div><h3>Materials and methods</h3><p><span><span><span>A parallel randomized controlled trial<span> included 200 maxillary primary incisors (100 teeth per group) restored either with PZCs or RSCS. The gingival health and plaque accumulation were assessed using </span></span>gingival index (GI) and </span>plaque index (PI) respectively. To evaluate the clinical performance, the modified United States </span>Public Health Service (USPHS) criteria were used. Intergroup comparison was performed using a Chi-square test. Restoration longevity was assessed over the predetermined intervals using Kaplan-Meier analysis. Generalized Estimating Equation (GEE) with robust standard errors was used to test the effect of time over the changes of repeated measures. The significance level was set to 5%.</p></div><div><h3>Results</h3><p>The gingival health around PZCs is significantly better than that of RCSCs after 6 months. However, at the following follow-ups, GI scores of both restorations were comparable (<em>p</em> > 0.05). All PZCs showed no plaque accumulation with a significant difference compared to the RCSCs over the follow-up intervals. The clinical performance of PZCs was significantly superior to that of RCSCs over the follow-ups in terms of retention and anatomical contour after 24 and 36 months. The survival rates of PZC and RCSC were 100% and 87% respectively.</p></div><div><h3>Conclusions</h3><p>After 36 months, the gingival health of PZC and RCSC was comparable. The retention and anatomical continuity of PZC were superior compared to RCSC.</p></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"34 1","pages":"Pages 19-26"},"PeriodicalIF":0.8,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139024954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
To determine the prevalence and presentation patterns of molar-incisor hypomineralisation (MIH) in Brazilian children.
Methods
A cross-sectional study was carried out with 715 individuals aged 8–17 years. MIH was diagnosed according to European Academy of Paediatric Dentistry (EAPD) criteria, using intraoral photographs. Data were analysed using Chi Square and Pearson's Correlation tests at α = 0.05.
Results
The prevalence of MIH was 15.66 %. Mild defects represented by demarcated yellow and brown opacities comprised 83.5 % of the total MIH lesions and the severity of MIH lesions increased significantly as age increased. The average number of first molars affected by MIH per child was 2.26, and 36 children (32.14 %) had at least one affected incisor. With the increase of affected molars, the number of incisors with opacities showed an obvious increasing. The maxillary left first molar was the most affected tooth, and the maxillary central incisors were the anterior teeth most frequently affected by MIH.
Conclusion
The prevalence of MIH was within the range of published studies and the severity of the defects was mostly mild.
{"title":"The prevalence and characteristics of molar-incisor hypomineralisation in Natal, Brazil","authors":"Layanny Silva Soares , Eloisa Cesario Fernandes , Patrícia Bittencourt Santos","doi":"10.1016/j.pdj.2023.12.003","DOIUrl":"10.1016/j.pdj.2023.12.003","url":null,"abstract":"<div><h3>Objectives</h3><p>To determine the prevalence and presentation patterns of molar-incisor hypomineralisation (MIH) in Brazilian children.</p></div><div><h3>Methods</h3><p><span>A cross-sectional study was carried out with 715 individuals aged 8–17 years. MIH was diagnosed according to European Academy of Paediatric Dentistry<span> (EAPD) criteria, using intraoral photographs. Data were analysed using Chi Square and Pearson's Correlation tests at </span></span><em>α</em> = 0.05.</p></div><div><h3>Results</h3><p><span>The prevalence of MIH was 15.66 %. Mild defects represented by demarcated yellow and brown opacities comprised 83.5 % of the total MIH lesions and the severity of MIH lesions increased significantly as age increased. The average number of first molars<span> affected by MIH per child was 2.26, and 36 children (32.14 %) had at least one affected incisor. With the increase of affected molars, the number of incisors with opacities showed an obvious increasing. The maxillary left first molar was the most affected tooth, and the </span></span>maxillary central incisors<span> were the anterior teeth most frequently affected by MIH.</span></p></div><div><h3>Conclusion</h3><p>The prevalence of MIH was within the range of published studies and the severity of the defects was mostly mild.</p></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"34 1","pages":"Pages 14-18"},"PeriodicalIF":0.8,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139018456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Reparative giant cell granuloma (RGCG) is a benign lesion with common gnathic expression in young patients. It is divided into aggressive and non-aggressive forms based on clinical and radiological features.
Case presentation
This is a case report of reparative granuloma of the maxilla in a six-year-old child who presented with asymptomatic gingival overgrowth in the maxillary teeth region which was surgically excised. An aggressive recurrence was noted eight months after excision, which was then excised with wider margins under general anesthesia. The case was finally diagnosed as the central type of RGCG with no further recurrence up till 36 months follow up.
Conclusion
Early recognition of RGCG is key to avoiding eventual demolitive outcomes. The complete wide excision of such lesions minimizes the chances of recurrence.
{"title":"Reparative giant cell granuloma in association with the developing maxilla: A case report","authors":"Raja Raghu , Manoj Jaiswal , Ashima Goyal , Vidya Rattan","doi":"10.1016/j.pdj.2023.09.001","DOIUrl":"10.1016/j.pdj.2023.09.001","url":null,"abstract":"<div><h3>Background</h3><p>Reparative giant cell granuloma (RGCG) is a benign lesion with common gnathic expression in young patients. It is divided into aggressive and non-aggressive forms based on clinical and radiological features.</p></div><div><h3>Case presentation</h3><p><span><span>This is a case report of reparative granuloma of the maxilla in a six-year-old child who presented with asymptomatic </span>gingival overgrowth in the maxillary teeth region which was surgically excised. An aggressive recurrence was noted eight months after excision, which was then excised with wider margins under </span>general anesthesia. The case was finally diagnosed as the central type of RGCG with no further recurrence up till 36 months follow up.</p></div><div><h3>Conclusion</h3><p>Early recognition of RGCG is key to avoiding eventual demolitive outcomes. The complete wide excision of such lesions minimizes the chances of recurrence.</p></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"33 3","pages":"Pages 223-227"},"PeriodicalIF":0.8,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134995538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-01DOI: 10.1016/j.pdj.2023.07.002
Vrushali Patil, Shilpa S. Naik, Sanjana R. Kodical, Rucha Bhise Patil, Shreya Khodke, Kiran Ghule
Introduction and aim
The aim of this study was to compare the clinical success and parental satisfaction of zirconia crowns (Kids-e-crowns™) with preformed stainless-steel crowns (3M™ ESPE) in the restoration of primary first and second molars.
Materials and methods
This randomized controlled clinical trial was designed as a split-mouth study. 100 teeth in 47 children aged between 3 and 7 years were selected and randomly assigned in two groups, each group containing 50 teeth. Restorations were evaluated at 24 h, 3, 6, 12 and 24 months recall appointments examining the following criteria-restoration failure, marginal integrity, gingival health, plaque accumulation, occlusion, opposing tooth wear and parental satisfaction.
Results
The performance of both the groups was comparable in terms of restoration failure, marginal integrity, gingival health, occlusion, opposing tooth wear. However, plaque accumulation was significantly higher in stainless-steel crowns than zirconia crowns.
Conclusion
Two year follow-up indicated that preformed zirconia crowns are an excellent aesthetic alternative to stainless-steel crowns as full coronal restorations in the paediatric population.
{"title":"Randomized clinical evaluation and parental satisfaction between zirconia crowns and stainless-steel crowns in primary molars: A 24 month follow up","authors":"Vrushali Patil, Shilpa S. Naik, Sanjana R. Kodical, Rucha Bhise Patil, Shreya Khodke, Kiran Ghule","doi":"10.1016/j.pdj.2023.07.002","DOIUrl":"10.1016/j.pdj.2023.07.002","url":null,"abstract":"<div><h3>Introduction and aim</h3><p>The aim of this study was to compare the clinical success and parental satisfaction of zirconia<span> crowns (Kids-e-crowns™) with preformed stainless-steel crowns (3M™ ESPE) in the restoration of primary first and second molars.</span></p></div><div><h3>Materials and methods</h3><p>This randomized controlled clinical trial was designed as a split-mouth study. 100 teeth in 47 children aged between 3 and 7 years were selected and randomly assigned in two groups, each group containing 50 teeth. Restorations were evaluated at 24 h, 3, 6, 12 and 24 months recall appointments examining the following criteria-restoration failure, marginal integrity, gingival health, plaque accumulation, occlusion, opposing tooth wear and parental satisfaction.</p></div><div><h3>Results</h3><p>The performance of both the groups was comparable in terms of restoration failure, marginal integrity, gingival health, occlusion, opposing tooth wear. However, plaque accumulation was significantly higher in stainless-steel crowns than zirconia crowns.</p></div><div><h3>Conclusion</h3><p>Two year follow-up indicated that preformed zirconia crowns are an excellent aesthetic alternative to stainless-steel crowns as full coronal restorations in the paediatric population.</p></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"33 3","pages":"Pages 175-181"},"PeriodicalIF":0.8,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46232895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-01DOI: 10.1016/j.pdj.2023.10.002
Özlem Akkemik , Servet Kesim , Ela Çabuk Renklibay , Deniz Ökdemir , Recep Saraymen , Selim Kurtoğlu
Objective
Hyperglycemia damages periodontal tissues by several mechanisms, primarily via dysregulated cytokine production. However, studies examining the relationship between cytokine levels, periodontal status, and diabetes-related parameters in teenage Type 1 Diabetes Mellitus (T1DM) patients are scarce. This investigation aimed to determine the levels of cytokines such as IL-33, IL-22, IL-17, IL-6, TNF-α and interferon (IFN)-γ in the saliva and gingival crevicular fluid (GCF) of T1DM teens and correlate these values with the patients’ periodontal health and DM-related parameters such as FBG, HbA1c, and diabetes duration.
Material and methods
Saliva, GCF samples and full-mouth clinical periodontal recordings were obtained from 40 T1DM and 40 non-diabetic teenagers. IFN-γ, TNF-α, IL-6, IL-17, IL-22, and IL-33 levels were analyzed by ELISA.
Results
Clinical bleeding on probing (BOP) and periodontal probing depth measures did not differ between the groups. The plaque and gingival index, as well as saliva and GCF levels of all cytokines tested were found to be comparatively higher in the cases. Correlations were detected between the duration of DM and salivary IL-17 and IL-33 levels, between FBG and GCF IL-17 levels, and between BOP and salivary IL-33 levels. Salivary IL-17 and IL-33 levels showed significant correlation solely with the duration of DM.
Conclusions
IL-33 and IL-17 appear to be a potent combination of cytokines in regulating salivary composition over time in Type I diabetic teens. A better understanding of the time-dependent release of salivary cytokines in Type I diabetic teens may help develop treatment strategies and improve oral health.
{"title":"Saliva and GCF cytokine levels in insulin-dependent diabetic teens and their relationship with metabolic status and disease duration","authors":"Özlem Akkemik , Servet Kesim , Ela Çabuk Renklibay , Deniz Ökdemir , Recep Saraymen , Selim Kurtoğlu","doi":"10.1016/j.pdj.2023.10.002","DOIUrl":"10.1016/j.pdj.2023.10.002","url":null,"abstract":"<div><h3>Objective</h3><p><span><span>Hyperglycemia damages periodontal tissues by several mechanisms, primarily via dysregulated </span>cytokine production<span><span>. However, studies examining the relationship between cytokine levels, periodontal status, and diabetes-related parameters in teenage Type 1 Diabetes Mellitus (T1DM) patients are scarce. This investigation aimed to determine the levels of cytokines such as IL-33, IL-22, IL-17, IL-6, TNF-α and interferon (IFN)-γ in the saliva and </span>gingival crevicular fluid<span> (GCF) of T1DM teens and correlate these values with the patients’ periodontal health and DM-related parameters such as FBG, </span></span></span>HbA1c, and diabetes duration.</p></div><div><h3>Material and methods</h3><p>Saliva, GCF samples and full-mouth clinical periodontal recordings were obtained from 40 T1DM and 40 non-diabetic teenagers. IFN-γ, TNF-α, IL-6, IL-17, IL-22, and IL-33 levels were analyzed by ELISA.</p></div><div><h3>Results</h3><p>Clinical bleeding on probing (BOP) and periodontal probing depth measures did not differ between the groups. The plaque and gingival index, as well as saliva and GCF levels of all cytokines tested were found to be comparatively higher in the cases. Correlations were detected between the duration of DM and salivary IL-17 and IL-33 levels, between FBG and GCF IL-17 levels, and between BOP and salivary IL-33 levels. Salivary IL-17 and IL-33 levels showed significant correlation solely with the duration of DM.</p></div><div><h3>Conclusions</h3><p>IL-33 and IL-17 appear to be a potent combination of cytokines in regulating salivary composition over time in Type I diabetic teens. A better understanding of the time-dependent release of salivary cytokines in Type I diabetic teens may help develop treatment strategies and improve oral health.</p></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"33 3","pages":"Pages 192-198"},"PeriodicalIF":0.8,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136159991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dens invaginatus (DI) is a developmental malformation caused by infolding of enamel and dentin toward the pulp cavity. A deep foramen cecum or unusual crown morphology is often seen in the area of affected teeth, which re most frequently in maxillary lateral incisors. DI is often associated with occurrence of internal caries without the clear symptoms and occasionally causes the pulp death, thus early diagnosis and treatment are important, as well as schedule follow-up examinations. Report here is a child aged 9 years 5 months with DI in the maxillary left lateral incisor. Based on cone beam computed tomography (CBCT) findings, the case was diagnosed as pulp necrosis and acute periapical abscess related to Oehlers type I DI. Endodontic treatment in consideration of the affected immature tooth and canal filling with calcium hydroxide paste were performed. Post-procedure CBCT imaging showed deposition of a calcified mass in the canal and reduced apical radiolucency, suggesting a favorable treatment outcome. Careful clinical and radiographic examinations should be conducted to identify DI and manage affected patients.
内陷牙(Dens invaginatus,DI)是一种发育畸形,由釉质和牙本质向牙髓腔内折引起。在受影响的牙齿区域经常可以看到深盲孔或异常的牙冠形态,这种情况最常见于上颌侧切牙。DI常伴有内龋的发生,但无明显症状,偶尔会导致牙髓坏死,因此早期诊断和治疗以及定期随访检查非常重要。这里报告的是一名患有上颌左侧切牙DI的9岁5个月儿童。根据锥形束计算机断层扫描(CBCT)结果,该病例被诊断为与 Oehlers I 型 DI 相关的牙髓坏死和急性根尖周脓肿。考虑到受影响的牙齿尚未发育成熟,对其进行了牙髓治疗,并用氢氧化钙糊剂进行了根管填充。治疗后的 CBCT 成像显示,钙化块在牙管内沉积,根尖放射线减少,表明治疗效果良好。应进行仔细的临床和放射学检查,以识别 DI 并处理受影响的患者。
{"title":"Diagnosis of maxillary lateral incisor dens invaginatus and therapeutic approach","authors":"Setsuyo Morimoto, Kana Goto, Asaumi Haruka, Tabata Keiko, Daiki Matsuoka, Shuhei Naka, Michiyo Matsumoto-Nakano","doi":"10.1016/j.pdj.2023.06.003","DOIUrl":"10.1016/j.pdj.2023.06.003","url":null,"abstract":"<div><p>Dens invaginatus<span><span> (DI) is a developmental malformation caused by infolding of enamel and dentin toward the pulp cavity. A deep foramen cecum or unusual crown morphology is often seen in the area of affected teeth, which re most frequently in </span>maxillary lateral incisors<span><span><span>. DI is often associated with occurrence of internal caries without the clear symptoms and occasionally causes the pulp death, thus early diagnosis and treatment<span> are important, as well as schedule follow-up examinations. Report here is a child aged 9 years 5 months with DI in the maxillary left lateral incisor. Based on </span></span>cone beam computed tomography (CBCT) findings, the case was diagnosed as </span>pulp necrosis<span><span> and acute periapical abscess related to Oehlers type I DI. </span>Endodontic<span> treatment in consideration of the affected immature tooth and canal filling with calcium hydroxide<span> paste were performed. Post-procedure CBCT imaging showed deposition of a calcified mass in the canal and reduced apical radiolucency, suggesting a favorable treatment outcome. Careful clinical and radiographic examinations should be conducted to identify DI and manage affected patients.</span></span></span></span></span></p></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"33 3","pages":"Pages 216-222"},"PeriodicalIF":0.8,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43777482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Studies have demonstrated high success rates of vital pulp therapy (VPT) in young patients; however, pulp canal calcification (PCC) is one of the most concerning complications in teeth that have undergone VPT. Currently, there is limited evidence regarding PCC in VPT-treated teeth.
Objective
This paper aimed to review the incidence of PCC and its associated complications, the factors that may influence PCC, and describe the clinical management of PCC in teeth that have undergone VPT.
Results
Previous studies have reported PCC incidences of 0%–45.0%, and factors that may be associated with the incidence and magnitude of PCC include preoperative diagnosis of the tooth, stage of root development, type of VPT, pulp dressing material, and follow-up period. However, the evidence on the complications of PCC in VPT-treated teeth is insufficient, and there is debate regarding PCC management.
Conclusions
Further research in this area will aid in the development of appropriate management strategies for PCC in VPT-treated teeth.
{"title":"Pulp canal calcification in young permanent teeth that have undergone vital pulp therapy: A review","authors":"Akarapong Boontankun, Chanika Manmontri, Nattakan Chaipattanawan, Papimon Chompu-inwai","doi":"10.1016/j.pdj.2023.05.003","DOIUrl":"10.1016/j.pdj.2023.05.003","url":null,"abstract":"<div><h3>Background</h3><p>Studies have demonstrated high success rates of vital pulp therapy (VPT) in young patients; however, pulp canal calcification (PCC) is one of the most concerning complications in teeth that have undergone VPT. Currently, there is limited evidence regarding PCC in VPT-treated teeth.</p></div><div><h3>Objective</h3><p>This paper aimed to review the incidence of PCC and its associated complications, the factors that may influence PCC, and describe the clinical management of PCC in teeth that have undergone VPT.</p></div><div><h3>Results</h3><p>Previous studies have reported PCC incidences of 0%–45.0%, and factors that may be associated with the incidence and magnitude of PCC include preoperative diagnosis of the tooth, stage of root development, type of VPT, pulp dressing material, and follow-up period. However, the evidence on the complications of PCC in VPT-treated teeth is insufficient, and there is debate regarding PCC management.</p></div><div><h3>Conclusions</h3><p>Further research in this area will aid in the development of appropriate management strategies for PCC in VPT-treated teeth.</p></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"33 3","pages":"Pages 199-210"},"PeriodicalIF":0.8,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48312574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}