首页 > 最新文献

Pediatric Dental Journal最新文献

英文 中文
Impact of gender and physical differences on the development of oral functions in children aged 6–17 years: A cross-sectional study 性别和体质差异对 6-17 岁儿童口腔功能发育的影响：横断面研究
IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE
Pediatric Dental Journal
Pub Date : 2023-12-01 DOI: 10.1016/j.pdj.2023.09.002
Shutaro Masuda, Yuko Fujita, Tomohiro Takeshima, Mai Fujimoto

Objective

This study aimed to establish the age at which oral function development completes in males and females, and to determine if obesity contributes to underdevelopment of oral function.

Materials and Methods

The study included 241 participants, including 121 males and 120 females aged 6 to 17 years. Following anthropometry and oral examination, maximum occlusal force, lip-closing strength, maximum tongue pressure, and masticatory performance were measured in all participants. The Rohrer Index and body mass index (BMI) were calculated using height and weight measurements, and these scores were grouped into underweight/severely underweight, normal weight, and overweight/obese categories.

Results

In males, maximum occlusal force, lip-closing strength, maximum tongue pressure, and masticatory performance increased with age. In females, maximum occlusal force, maximum tongue pressure, and masticatory performance peaked during the teenage years. Masticatory performance in the overweight/obese male group was significantly lower than in the normal weight group (p < 0.05). In females, maximum occlusal force in the underweight/severely underweight group and maximum tongue pressure in the overweight/obese group were significantly lower than in the normal weight group (both, p < 0.05).

Conclusion

Growth patterns of each oral function differ considerably between males and females. Oral functions in females typically reached their peak earlier than in males, with most functions peaking during the teenage years. Overweight/obesity contribute to the underdevelopment of oral functions in both genders. Underweight may also hinder oral function development in females.

本研究旨在确定男性和女性口腔功能发育完成的年龄，并确定肥胖是否会导致口腔功能发育不全。在进行人体测量和口腔检查后，对所有参与者的最大咬合力、闭唇力、最大舌压力和咀嚼功能进行了测量。根据身高和体重测量值计算罗尔指数和体重指数（BMI），并将这些分数分为体重不足/严重不足、体重正常和超重/肥胖三个类别。女性的最大咬合力、最大舌压力和咀嚼能力在青少年时期达到顶峰。超重/肥胖男性组的咀嚼能力明显低于正常体重组（p < 0.05）。女性中，体重不足/严重体重不足组的最大咬合力和超重/肥胖组的最大舌压力明显低于正常体重组（均为 p < 0.05）。女性的口腔功能通常比男性更早达到高峰，大多数功能在青少年时期达到高峰。超重/肥胖会导致男女口腔功能发育不全。体重过轻也会阻碍女性口腔功能的发育。
{"title":"Impact of gender and physical differences on the development of oral functions in children aged 6–17 years: A cross-sectional study","authors":"Shutaro Masuda,&nbsp;Yuko Fujita,&nbsp;Tomohiro Takeshima,&nbsp;Mai Fujimoto","doi":"10.1016/j.pdj.2023.09.002","DOIUrl":"10.1016/j.pdj.2023.09.002","url":null,"abstract":"<div><h3>Objective</h3><p>This study aimed to establish the age at which oral function development completes in males and females, and to determine if obesity contributes to underdevelopment of oral function.</p></div><div><h3>Materials and Methods</h3><p>The study included 241 participants, including 121 males and 120 females aged 6 to 17 years. Following anthropometry and oral examination, maximum occlusal force, lip-closing strength, maximum tongue pressure, and masticatory performance were measured in all participants. The Rohrer Index and body mass index (BMI) were calculated using height and weight measurements, and these scores were grouped into underweight/severely underweight, normal weight, and overweight/obese categories.</p></div><div><h3>Results</h3><p>In males, maximum occlusal force, lip-closing strength, maximum tongue pressure, and masticatory performance increased with age. In females, maximum occlusal force, maximum tongue pressure, and masticatory performance peaked during the teenage years. Masticatory performance in the overweight/obese male group was significantly lower than in the normal weight group (<em>p</em> &lt; 0.05). In females, maximum occlusal force in the underweight/severely underweight group and maximum tongue pressure in the overweight/obese group were significantly lower than in the normal weight group (both, p &lt; 0.05).</p></div><div><h3>Conclusion</h3><p>Growth patterns of each oral function differ considerably between males and females. Oral functions in females typically reached their peak earlier than in males, with most functions peaking during the teenage years. Overweight/obesity contribute to the underdevelopment of oral functions in both genders. Underweight may also hinder oral function development in females.</p></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"33 3","pages":"Pages 182-191"},"PeriodicalIF":0.8,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0917239423000435/pdfft?md5=ba71ba8804f257d9bdc438079bd7a25c&pid=1-s2.0-S0917239423000435-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135605343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dens invaginatus of fourteen teeth in a pediatric patient 一名儿童患者 14 颗牙齿的内陷畸形
IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE
Pediatric Dental Journal
Pub Date : 2023-12-01 DOI: 10.1016/j.pdj.2023.10.001
Momoko Usuda , Tatsuya Akitomo , Mariko Kametani, Satoru Kusaka, Chieko Mitsuhata, Ryota Nomura

Background

Dens invaginatus is a dental anomaly in which the enamel and dentin are deeply enfolded in the pulp cavity.

Case presentation

A 12-year-and-8-month-old Japanese male was diagnosed with 14 permanent teeth with dens invaginatus. We covered the premolars with glass-ionomer liner, and the pain gradually resolved. Eight months later, periapical radiographs revealed that their roots had developed, confirming the survival of the pulp.

Conclusion

The patient had not received regular check-ups, and dens invaginatus was diagnosed for the first time when pain occurred. This report highlights the importance of regular dental check-ups.

病例介绍 一名 12 岁零 8 个月大的日本男性被诊断为 14 颗恒牙内陷。我们用玻璃-离子衬垫覆盖了前臼齿，疼痛逐渐缓解。八个月后，根尖周炎 X 光片显示这些牙齿的牙根已经发育，证实了牙髓的存活。本报告强调了定期牙科检查的重要性。
{"title":"Dens invaginatus of fourteen teeth in a pediatric patient","authors":"Momoko Usuda ,&nbsp;Tatsuya Akitomo ,&nbsp;Mariko Kametani,&nbsp;Satoru Kusaka,&nbsp;Chieko Mitsuhata,&nbsp;Ryota Nomura","doi":"10.1016/j.pdj.2023.10.001","DOIUrl":"10.1016/j.pdj.2023.10.001","url":null,"abstract":"<div><h3>Background</h3><p>Dens invaginatus<span> is a dental anomaly in which the enamel and dentin are deeply enfolded in the pulp cavity.</span></p></div><div><h3>Case presentation</h3><p>A 12-year-and-8-month-old Japanese male was diagnosed with 14 permanent teeth with dens invaginatus. We covered the premolars with glass-ionomer liner, and the pain gradually resolved. Eight months later, periapical radiographs revealed that their roots had developed, confirming the survival of the pulp.</p></div><div><h3>Conclusion</h3><p>The patient had not received regular check-ups, and dens invaginatus was diagnosed for the first time when pain occurred. This report highlights the importance of regular dental check-ups.</p></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"33 3","pages":"Pages 240-245"},"PeriodicalIF":0.8,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135809432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Survey of primary tooth eruption status of down syndrome in Japan: Comparison with the Japanese National Survey of Dental Diseases 日本唐氏综合症患者原牙萌出状况调查：与日本全国牙科疾病调查的比较
IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE
Pediatric Dental Journal
Pub Date : 2023-12-01 DOI: 10.1016/j.pdj.2023.07.001
Kazutaka Noda , Shinhachi Hanaoka , Masahiro Watanabe , Kazumi Kubota , Koji Yamauchi , Kaoru Kobayashi , Hirokatsu Harasawa , Risa Ikeda , Tomoya Yamahata , Takahiro Funatsu , Masakazu Ikeda , Yoshiharu Mukai , Shouji Hironaka

Introduction

Down syndrome (DS) can cause irregular dental eruption patterns and hypodontia. However, data on primary tooth eruption with DS in Japan are insufficient. Therefore, this study aimed to conduct a questionnaire survey to predict dental abnormalities in DS based on tooth eruption status.

Methods

A questionnaire survey on the age, sex, number of present teeth, and dental formula of patients with DS was conducted at facilities providing dental care for the disabled in Japan, and the results were compared with those of the Survey of Dental Diseases used as for the control survey.

Results

A total of 3656 valid responses were received. This study was analyzed according to the age group of the Survey of Dental Diseases. At 1–14 years old, the mean number of primary teeth per patient was the highest at 4 years old (19.3 teeth). The largest difference from the control survey was at 1 year old, and the difference decreased with age until 4 years. At 3–5 years old, the rate of individual primary tooth eruptions was 14.2% lower for the mandibular primary lateral incisors than that in the control survey. At 15 years old or older, the percentage of people who had persistence of primary teeth was 19.2%. The second primary molars were the most common persistent primary teeth.

Conclusion

DS is characterized by delayed tooth eruption, high incidence of missing teeth, particularly the mandibular primary lateral incisors, and persistence of primary teeth. These findings indicate the importance of developmental support and oral management.

导言唐氏综合征（Down Syndrome，DS）可导致牙齿萌出模式不规则和牙列不齐。然而，在日本，有关DS患者原牙萌出的数据并不充分。方法 在日本为残障人士提供牙科治疗的机构中，对患有唐氏综合征的患者的年龄、性别、现存牙齿数量和牙齿形态进行了问卷调查，并将调查结果与作为对照调查的牙科疾病调查的结果进行了比较。本研究根据牙科疾病调查的年龄组进行分析。在 1-14 岁年龄组中，每名患者的平均乳牙数以 4 岁最高（19.3 颗）。与对照调查相比，1 岁时的差异最大，随着年龄的增长，差异逐渐缩小，直到 4 岁。3-5 岁时，下颌初级侧切牙的单个乳牙萌出率比对照调查低 14.2%。在 15 岁或 15 岁以上的人群中，原牙持续萌出的比例为 19.2%。结论DS 的特点是牙齿萌出延迟、牙齿缺失率高（尤其是下颌初级侧切牙）以及初级牙齿持续存在。这些发现表明了发育支持和口腔管理的重要性。
{"title":"Survey of primary tooth eruption status of down syndrome in Japan: Comparison with the Japanese National Survey of Dental Diseases","authors":"Kazutaka Noda ,&nbsp;Shinhachi Hanaoka ,&nbsp;Masahiro Watanabe ,&nbsp;Kazumi Kubota ,&nbsp;Koji Yamauchi ,&nbsp;Kaoru Kobayashi ,&nbsp;Hirokatsu Harasawa ,&nbsp;Risa Ikeda ,&nbsp;Tomoya Yamahata ,&nbsp;Takahiro Funatsu ,&nbsp;Masakazu Ikeda ,&nbsp;Yoshiharu Mukai ,&nbsp;Shouji Hironaka","doi":"10.1016/j.pdj.2023.07.001","DOIUrl":"10.1016/j.pdj.2023.07.001","url":null,"abstract":"<div><h3>Introduction</h3><p>Down syndrome (DS) can cause irregular dental eruption patterns and hypodontia. However, data on primary tooth eruption with DS in Japan are insufficient. Therefore, this study aimed to conduct a questionnaire survey to predict dental abnormalities in DS based on tooth eruption status.</p></div><div><h3>Methods</h3><p>A questionnaire survey on the age, sex, number of present teeth, and dental formula of patients with DS was conducted at facilities providing dental care for the disabled in Japan, and the results were compared with those of the Survey of Dental Diseases used as for the control survey.</p></div><div><h3>Results</h3><p>A total of 3656 valid responses were received. This study was analyzed according to the age group of the Survey of Dental Diseases. At 1–14 years old, the mean number of primary teeth per patient was the highest at 4 years old (19.3 teeth). The largest difference from the control survey was at 1 year old, and the difference decreased with age until 4 years. At 3–5 years old, the rate of individual primary tooth eruptions was 14.2% lower for the mandibular primary lateral incisors than that in the control survey. At 15 years old or older, the percentage of people who had persistence of primary teeth was 19.2%. The second primary molars were the most common persistent primary teeth.</p></div><div><h3>Conclusion</h3><p>DS is characterized by delayed tooth eruption, high incidence of missing teeth, particularly the mandibular primary lateral incisors, and persistence of primary teeth. These findings indicate the importance of developmental support and oral management.</p></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"33 3","pages":"Pages 167-174"},"PeriodicalIF":0.8,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S091723942300040X/pdfft?md5=6431715afb7103dd0cf04567ca54ce5c&pid=1-s2.0-S091723942300040X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"55222606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case of dilaceration of a permanent tooth resulting from trauma to the preceding primary tooth 因前一颗恒牙外伤导致恒牙稀释的病例
IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE
Pediatric Dental Journal
Pub Date : 2023-12-01 DOI: 10.1016/j.pdj.2023.09.003
Shunsuke Kako , Masako Tabuchi , Yuki Aoki , Takuma Sato , Hiroyuki Nawa , Ken Miyazawa

Background

Trauma to primary teeth can cause dilaceration of permanent teeth.

Case presentation

A boy aged 14 years 6 months at initial presentation had a history of dental trauma at age 4 years. Radiography revealed significant dilaceration and impaction of the maxillary left central incisor, and preservation of the tooth was judged to be infeasible. The necessity of extracting the maxillary left central incisor was supported by examination using the latest digital technology.

Conclusion

Digital technology can play an important role in deciding treatment strategies for an impacted tooth with dilaceration.

病例介绍 一名 14 岁 6 个月大的男孩在 4 岁时有过牙齿外伤史。放射线检查显示上颌左侧中切牙有明显的扩张和嵌塞，判断保留该牙不可行。通过使用最新的数字技术进行检查，证实了拔除上颌左中切牙的必要性。
{"title":"A case of dilaceration of a permanent tooth resulting from trauma to the preceding primary tooth","authors":"Shunsuke Kako ,&nbsp;Masako Tabuchi ,&nbsp;Yuki Aoki ,&nbsp;Takuma Sato ,&nbsp;Hiroyuki Nawa ,&nbsp;Ken Miyazawa","doi":"10.1016/j.pdj.2023.09.003","DOIUrl":"10.1016/j.pdj.2023.09.003","url":null,"abstract":"<div><h3>Background</h3><p><span>Trauma to primary teeth can cause </span>dilaceration of permanent teeth.</p></div><div><h3>Case presentation</h3><p>A boy aged 14 years 6 months at initial presentation had a history of dental trauma at age 4 years. Radiography revealed significant dilaceration and impaction of the maxillary left central incisor, and preservation of the tooth was judged to be infeasible. The necessity of extracting the maxillary left central incisor was supported by examination using the latest digital technology.</p></div><div><h3>Conclusion</h3><p><span>Digital technology can play an important role in deciding treatment strategies for an </span>impacted tooth with dilaceration.</p></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"33 3","pages":"Pages 228-239"},"PeriodicalIF":0.8,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135761628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Conservative management of Mycoplasma pneumoniae-induced Stevens Johnson syndrome in a paediatric patient: A case report 儿科支原体肺炎诱发史蒂文斯-约翰逊综合征的保守治疗：病例报告
IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE
Pediatric Dental Journal
Pub Date : 2023-10-30 DOI: 10.1016/j.pdj.2023.10.003
Amanda Lin , Neeta Prabhu

Background

Stevens-Johnson Syndrome (SJS) is a rare and potentially life-threatening condition causing blistering and epithelial sloughing of the skin and mucous membranes. It is most commonly caused by infective pathogens or drugs.

Case presentation

A 14-year-old male patient presented with reduced oral intake following painful oral ulcerations secondary to a diagnosis of Mycoplasma pneumoniae-induced SJS. Treatment involved intravenous fluids, antimicrobials and analgesia, alongside atraumatic conservative management of the oral mucosa.

Conclusion

While there are no evidence-based treatment guidelines for Mycoplasma pneumoniae-induced SJS, conservative care is the cornerstone of management of paediatric presentations.

背景史蒂文斯-约翰逊综合征（Stevens-Johnson Syndrome，SJS）是一种罕见的、可能危及生命的疾病，会导致皮肤和粘膜出现水疱和上皮脱落。病例介绍一名 14 岁的男性患者被诊断为肺炎支原体诱发的 SJS，继发疼痛性口腔溃疡后，口腔摄入量减少。治疗包括静脉输液、抗菌药和镇痛，以及对口腔粘膜进行无创伤的保守治疗。结论虽然肺炎支原体诱发的 SJS 尚无循证治疗指南，但保守治疗是儿科病例治疗的基石。
{"title":"Conservative management of Mycoplasma pneumoniae-induced Stevens Johnson syndrome in a paediatric patient: A case report","authors":"Amanda Lin ,&nbsp;Neeta Prabhu","doi":"10.1016/j.pdj.2023.10.003","DOIUrl":"10.1016/j.pdj.2023.10.003","url":null,"abstract":"<div><h3>Background</h3><p>Stevens-Johnson Syndrome (SJS) is a rare and potentially life-threatening condition causing blistering and epithelial sloughing of the skin and mucous membranes. It is most commonly caused by infective pathogens or drugs.</p></div><div><h3>Case presentation</h3><p>A 14-year-old male patient presented with reduced oral intake following painful oral ulcerations secondary to a diagnosis of <em>Mycoplasma pneumoniae</em>-induced SJS. Treatment involved intravenous fluids, antimicrobials and analgesia, alongside atraumatic conservative management of the oral mucosa.</p></div><div><h3>Conclusion</h3><p>While there are no evidence-based treatment guidelines for <em>Mycoplasma pneumoniae</em>-induced SJS, conservative care is the cornerstone of management of paediatric presentations.</p></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"34 1","pages":"Pages 46-48"},"PeriodicalIF":0.8,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0917239423000472/pdfft?md5=da6b20581357a3c54216f4340302602a&pid=1-s2.0-S0917239423000472-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136127708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of oral health characteristics in pediatric cancer and cancer free patients: A multicenter study 儿童癌症患者与非癌症患者口腔健康特征的比较:一项多中心研究
IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE
Pediatric Dental Journal
Pub Date : 2023-08-01 DOI: 10.1016/j.pdj.2023.05.001
Chantal Kerbage , Anthony T. Macari , Anthony Kerbage , Nada Chedid

Introduction

Comparing oral health of cancer to non-cancer children proves that cancer and its treatment can cause oral complications.

Design

Two groups of children, 50 treated for cancer, and 51 cancer-free, at two different centers, signed informed consent forms. Both the examination of teeth, oral functions and soft tissue with a questionnaire including the patients’ demographic characteristics, medical history, dietary and oral hygiene, and changes due to the oncologic treatment allowed gathering data.

Results

The two groups had no demographic nor socio-economic differences. Dietary habits were not significantly different. Daily brushing was more frequent in cancer-free (96.1%) versus sick (76%) children. Oral hygiene was poor (34%) or very poor (24%) in cancer patients and average for non-cancer subjects (68.6%). Cancer patients had more caries, without significant differences between groups. Gingiva was healthy in 96.1% of non-cancer and 76% of cancer patients (p = 0.044). In cancer patients, intra-oral soft tissue lesions were aphtous ulcers (52.9%), candidiasis (23.5%), and herpes (17.6%). Xerostomia was significantly different (p = 0.001) between cancer (32%) and non-cancer subjects (3.9%). Chemotherapy alone is an independent predictor of poor oral health (HR 17.7, 95% CI [5.2–60.9], p < 0.001).

Conclusion

Cancer patients had poor oral health compared to non-cancer children, with insufficient knowledge concerning the relationship between oral and general health. Education programs, screenings and treatment at cancer centers may help reduce risks of complications.

将癌症儿童与非癌症儿童的口腔健康状况进行比较，证明癌症及其治疗可引起口腔并发症。设计两组儿童，50名接受癌症治疗，51名未患癌症，在两个不同的中心签署知情同意书。通过对牙齿、口腔功能和软组织的检查和问卷调查，包括患者的人口统计学特征、病史、饮食和口腔卫生以及肿瘤治疗引起的变化，可以收集数据。结果两组没有人口统计学和社会经济差异。饮食习惯差异不显著。无癌儿童(96.1%)每天刷牙的频率高于患病儿童(76%)。癌症患者的口腔卫生差(34%)或非常差(24%)，非癌症受试者的平均水平(68.6%)。癌症患者有更多的龋齿，组间无显著差异。96.1%的非癌症患者牙龈健康，76%的癌症患者牙龈健康(p = 0.044)。在癌症患者中，口腔内软组织病变主要为无孔溃疡(52.9%)、念珠菌病(23.5%)和疱疹(17.6%)。癌症患者(32%)和非癌症患者(3.9%)的口干性差异有统计学意义(p = 0.001)。单独化疗是口腔健康状况不佳的独立预测因子(HR 17.7, 95% CI [5.2-60.9]， p <0.001)。结论癌症患儿口腔健康状况较非癌症患儿差，对口腔与整体健康的关系认识不足。癌症中心的教育项目、筛查和治疗可能有助于降低并发症的风险。
{"title":"Comparison of oral health characteristics in pediatric cancer and cancer free patients: A multicenter study","authors":"Chantal Kerbage ,&nbsp;Anthony T. Macari ,&nbsp;Anthony Kerbage ,&nbsp;Nada Chedid","doi":"10.1016/j.pdj.2023.05.001","DOIUrl":"10.1016/j.pdj.2023.05.001","url":null,"abstract":"<div><h3>Introduction</h3><p>Comparing oral health of cancer to non-cancer children proves that cancer and its treatment can cause oral complications.</p></div><div><h3>Design</h3><p>Two groups of children, 50 treated for cancer, and 51 cancer-free, at two different centers, signed informed consent<span> forms. Both the examination of teeth, oral functions and soft tissue with a questionnaire including the patients’ demographic characteristics, medical history, dietary and oral hygiene, and changes due to the oncologic treatment allowed gathering data.</span></p></div><div><h3>Results</h3><p>The two groups had no demographic nor socio-economic differences. Dietary habits were not significantly different. Daily brushing was more frequent in cancer-free (96.1%) versus sick (76%) children. Oral hygiene was poor (34%) or very poor (24%) in cancer patients and average for non-cancer subjects (68.6%). Cancer patients had more caries, without significant differences between groups. Gingiva<span><span> was healthy in 96.1% of non-cancer and 76% of cancer patients (p = 0.044). In cancer patients, intra-oral soft tissue lesions were aphtous ulcers (52.9%), </span>candidiasis<span> (23.5%), and herpes (17.6%). Xerostomia was significantly different (p = 0.001) between cancer (32%) and non-cancer subjects (3.9%). Chemotherapy alone is an independent predictor of poor oral health (HR 17.7, 95% CI [5.2–60.9], p &lt; 0.001).</span></span></p></div><div><h3>Conclusion</h3><p>Cancer patients had poor oral health compared to non-cancer children, with insufficient knowledge concerning the relationship between oral and general health. Education programs, screenings and treatment at cancer centers may help reduce risks of complications.</p></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"33 2","pages":"Pages 139-146"},"PeriodicalIF":0.8,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43361100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Application of the salivary multi test in children with severe congenital neutropenia: A case report 唾液多项试验在小儿重度先天性中性粒细胞减少症中的应用1例
IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE
Pediatric Dental Journal
Pub Date : 2023-08-01 DOI: 10.1016/j.pdj.2023.05.002
Yuko Iwamoto , Nobuyuki Tatsukawa , Yasumasa Irie , Satoru Kusaka , Chieko Mitsuhata , Ryota Nomura

Background

A Salivary Multi Test® (SMT®) was used in children with severe congenital neutropenia who were admitted to the pediatrics department of our hospital.

Case presentation

SMT® was conducted on three patients with severe congenital neutropenia. Rod and segmented neutrophil counts in the peripheral blood showed fluctuations similar to those of the “leukocyte level” in SMT®.

Conclusion

SMT®, which uses saliva samples that are non-invasive and can be easily collected, may help manage systemic diseases.

研究背景:对我院儿科收治的严重先天性中性粒细胞减少症患儿进行唾液多重检测(SMT)。smt®应用于3例重度先天性中性粒细胞减少症患者。外周血中棒状和节段中性粒细胞计数的波动与SMT®中“白细胞水平”的波动相似。结论smt®使用的唾液样本无创且易于收集，可能有助于治疗全身性疾病。
{"title":"Application of the salivary multi test in children with severe congenital neutropenia: A case report","authors":"Yuko Iwamoto ,&nbsp;Nobuyuki Tatsukawa ,&nbsp;Yasumasa Irie ,&nbsp;Satoru Kusaka ,&nbsp;Chieko Mitsuhata ,&nbsp;Ryota Nomura","doi":"10.1016/j.pdj.2023.05.002","DOIUrl":"10.1016/j.pdj.2023.05.002","url":null,"abstract":"<div><h3>Background</h3><p>A Salivary Multi Test® (SMT®) was used in children with severe congenital neutropenia<span> who were admitted to the pediatrics department of our hospital.</span></p></div><div><h3>Case presentation</h3><p>SMT® was conducted on three patients with severe congenital neutropenia. Rod and segmented neutrophil counts in the peripheral blood showed fluctuations similar to those of the “leukocyte level” in SMT®.</p></div><div><h3>Conclusion</h3><p>SMT®, which uses saliva samples that are non-invasive and can be easily collected, may help manage systemic diseases.</p></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"33 2","pages":"Pages 152-158"},"PeriodicalIF":0.8,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47162953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Concentrations of interleukin-32, interleukin −10, interleukin −6, and TNF-alfa are higher in saliva of children with early childhood caries 早期儿童龋齿患者唾液中白细胞介素-32、白细胞介素- 10、白细胞介素- 6和tnf - α的浓度较高
IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE
Pediatric Dental Journal
Pub Date : 2023-08-01 DOI: 10.1016/j.pdj.2023.03.005
Ecem Gur , Sultan Keles , Ozge Cevik

Aim

To investigate if the levels of interleukin-32 (IL-32), interleukin-10 (IL-10), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α) in the saliva are associated with early childhood caries.

Methods

A total of 56 patients aged between 36 and 71 months with dental caries and without caries were included in this study. The patients’ caries status was evaluated according to the dmft and dmfs indices. IL-32, IL-10, IL-6, and TNF-α levels in the saliva samples of the patients were measured by ELISA.

Results

There were no statistically significant differences in the oral hygiene and nutritional habits, plaque index, and gingival index values between the ECC and control groups evaluated in the study (p > 0.05). The ECC group's salivary IL-32, IL-10, IL-6, and TNF-α levels were statistically significantly higher than the control group (p < 0.001).

Conclusion

The high levels of IL-32, IL-10, IL-6, and TNF-α detected in the saliva of children with ECC reveal that these cytokines may play a potential role in ECC pathogenesis. Salivary levels of IL-32, IL-10, IL-6, and TNF-α are associated with early childhood caries in children.

目的探讨唾液中白细胞介素-32 (IL-32)、白细胞介素-10 (IL-10)、白细胞介素-6 (IL-6)和肿瘤坏死因子-α (TNF-α)水平与儿童早期龋齿的关系。方法选取36 ~ 71月龄有龋和无龋患者56例。根据dmft和dmfs指数评价患者的龋病状况。采用ELISA法检测患者唾液中IL-32、IL-10、IL-6、TNF-α水平。结果ECC组与对照组在口腔卫生和营养习惯、菌斑指数、牙龈指数等方面差异均无统计学意义(p >0.05)。ECC组唾液IL-32、IL-10、IL-6、TNF-α水平均显著高于对照组(p <0.001)。结论ECC患儿唾液中IL-32、IL-10、IL-6、TNF-α水平较高，提示这些细胞因子可能在ECC发病过程中发挥潜在作用。唾液中IL-32、IL-10、IL-6和TNF-α水平与儿童早期龋齿相关。
{"title":"Concentrations of interleukin-32, interleukin −10, interleukin −6, and TNF-alfa are higher in saliva of children with early childhood caries","authors":"Ecem Gur ,&nbsp;Sultan Keles ,&nbsp;Ozge Cevik","doi":"10.1016/j.pdj.2023.03.005","DOIUrl":"10.1016/j.pdj.2023.03.005","url":null,"abstract":"<div><h3>Aim</h3><p>To investigate if the levels of interleukin-32 (IL-32), interleukin-10 (IL-10), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α) in the saliva are associated with early childhood caries.</p></div><div><h3>Methods</h3><p>A total of 56 patients aged between 36 and 71 months with dental caries and without caries were included in this study. The patients’ caries status was evaluated according to the dmft and dmfs indices. IL-32, IL-10, IL-6, and TNF-α levels in the saliva samples of the patients were measured by ELISA.</p></div><div><h3>Results</h3><p>There were no statistically significant differences in the oral hygiene and nutritional habits, plaque index<span>, and gingival index values between the ECC and control groups evaluated in the study (p &gt; 0.05). The ECC group's salivary IL-32, IL-10, IL-6, and TNF-α levels were statistically significantly higher than the control group (p &lt; 0.001).</span></p></div><div><h3>Conclusion</h3><p>The high levels of IL-32, IL-10, IL-6, and TNF-α detected in the saliva of children with ECC reveal that these cytokines may play a potential role in ECC pathogenesis. Salivary levels of IL-32, IL-10, IL-6, and TNF-α are associated with early childhood caries in children.</p></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"33 2","pages":"Pages 116-124"},"PeriodicalIF":0.8,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41898851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Single-cell RNA-sequence of dental epithelium reveals responsible genes of dental anomalies in human 人牙上皮单细胞rna序列揭示牙畸形的相关基因
IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE
Pediatric Dental Journal
Pub Date : 2023-08-01 DOI: 10.1016/j.pdj.2023.03.004
Kifu Miyata , Yuta Chiba , Triana Marchelina , Saori Inada , Sae Oka , Kan Saito , Aya Yamada , Satoshi Fukumoto

Objectives

Dental anomalies show various symptoms and some of them are accompanied with inherited diseases. However, only a few of responsible genes of dental anomalies are identified. In this study, we aimed to establish a novel strategy for identification of responsible genes of dental anomalies using integration of single-cell RNA-sequence (scRNA-seq) and Online Mendelian Inheritance in Man (OMIM).

Materials and methods

Single cells were isolated from mandibular incisor of post-natal day (P) seven mice and scRNA-seq were performed. Top 20 differentially expressed genes between clusters were identified and used for further analyses. Inherited diseases of differentially expressed genes and their Clinical Synopsis were examined using OMIM.

Results

The prevalence of inherited disease was 43/80 genes (53.8%) and inherited diseases which associate with dental anomalies were 34/96 diseases (35.4%); 14.6% in enamel abnormality, 4.1% in dentin abnormality, and 16.7% in other abnormality. The prevalence of enamel abnormality was the highest in ameloblast, while that of other abnormality was high in non-ameloblast cell types. Chromosomal mapping of differentially expressed genes indicated that chromosome 4 has “hotspots” of dental anomalies-associated genes.

Conclusion

The differentially expressed genes in dental epithelial cells were responsible for inherited disease which shows dental anomalies. The strategy employed in this study will contribute to identify the responsible gene for dental anomalies.

目的牙畸形表现为多种症状，有的伴有遗传性疾病。然而，只有少数负责基因的牙齿异常被确定。在这项研究中，我们旨在通过整合单细胞rna序列(scRNA-seq)和人类在线孟德尔遗传(OMIM)，建立一种鉴定牙齿异常相关基因的新策略。材料和方法从出生日(P) 7只小鼠的下颌切牙中分离单细胞，进行scrna测序。鉴定出集群间差异表达最多的20个基因，并用于进一步分析。应用OMIM对差异表达基因遗传病进行了临床分析。结果遗传疾病患病率为43/80个(53.8%)，与牙畸形相关的遗传疾病患病率为34/96个(35.4%);牙本质异常14.6%，牙本质异常4.1%，其他异常16.7%。釉质异常发生率以成釉细胞最高，其他异常发生率在非成釉细胞中较高。差异表达基因的染色体定位表明，4号染色体上存在牙齿异常相关基因的“热点”。结论牙上皮细胞差异表达基因是导致牙畸形的遗传疾病的主要原因。本研究采用的策略将有助于确定牙齿异常的负责基因。
{"title":"Single-cell RNA-sequence of dental epithelium reveals responsible genes of dental anomalies in human","authors":"Kifu Miyata ,&nbsp;Yuta Chiba ,&nbsp;Triana Marchelina ,&nbsp;Saori Inada ,&nbsp;Sae Oka ,&nbsp;Kan Saito ,&nbsp;Aya Yamada ,&nbsp;Satoshi Fukumoto","doi":"10.1016/j.pdj.2023.03.004","DOIUrl":"10.1016/j.pdj.2023.03.004","url":null,"abstract":"<div><h3>Objectives</h3><p><span>Dental anomalies show various symptoms and some of them are accompanied with inherited </span>diseases. However, only a few of responsible genes of dental anomalies are identified. In this study, we aimed to establish a novel strategy for identification of responsible genes of dental anomalies using integration of single-cell RNA-sequence (scRNA-seq) and Online Mendelian Inheritance in Man (OMIM).</p></div><div><h3>Materials and methods</h3><p>Single cells were isolated from mandibular incisor of post-natal day (P) seven mice and scRNA-seq were performed. Top 20 differentially expressed genes between clusters were identified and used for further analyses. Inherited diseases of differentially expressed genes and their Clinical Synopsis were examined using OMIM.</p></div><div><h3>Results</h3><p><span>The prevalence of inherited disease was 43/80 genes (53.8%) and inherited diseases which associate with dental anomalies were 34/96 diseases (35.4%); 14.6% in enamel abnormality, 4.1% in dentin abnormality, and 16.7% in other abnormality. The prevalence of enamel abnormality was the highest in </span>ameloblast<span>, while that of other abnormality was high in non-ameloblast cell types. Chromosomal mapping of differentially expressed genes indicated that chromosome 4 has “hotspots” of dental anomalies-associated genes.</span></p></div><div><h3>Conclusion</h3><p>The differentially expressed genes in dental epithelial cells were responsible for inherited disease which shows dental anomalies. The strategy employed in this study will contribute to identify the responsible gene for dental anomalies.</p></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"33 2","pages":"Pages 102-115"},"PeriodicalIF":0.8,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49063053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of antibacterial efficacy of ultrasonic-activated and inactivated chlorhexidine (solution and gel) in infected root canals of primary anterior teeth 超声激活和灭活氯己定（溶液和凝胶）对原发性前牙感染根管的抗菌效果评价
IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE
Pediatric Dental Journal
Pub Date : 2023-08-01 DOI: 10.1016/j.pdj.2023.03.003
Rahaf Kharsa , Mohanad Laflouf , Taissir Albouni , Hasan Alzoubi

Objectives

Sodium hypochlorite is not able to completely eliminate Enterococcus faecalis inside root canals. Therefore, this study aimed to evaluate chlorhexidine gel and solution in eliminating bacterial counts within infected root canals of primary anterior teeth.

Materials and methods

This study included 75 primary anterior teeth in 27 healthy children and it was divided into five groups: Group 1: Chlorhexidine 2% solution, Group 2: Chlorhexidine 2% solution activated by ultrasonic, Group 3: Chlorhexidine 2% gel, Group 4: Chlorhexidine 2% gel activated by ultrasonic, and Group 5: Sodium hypochlorite solution 5.25%. The preliminary smear for bacterial study (S1) was taken before irrigation. The root canals were irrigated in a quantity of 7 ml using a 31-gauge irrigation needle, and irrigant activation was 2 cycles (20 s). The final smear for bacterial study (S2) was taken after irrigation.

Results

There were no statistically differences in the mean percentage change in the decimal logarithm of the anaerobic bacterial colony count, but statistically differences were found for aerobic bacteria. For aerobic bacteria: CHx 2% solution activated better than CHx 2% and NaOCl 5.25% solutions, CHx 2% gel better than CHx 2% solution, CHx 2% gel activated better than CHx 2% and NaOCl 5.25% solutions.

Conclusion

All irrigation solutions used are effective in eliminating bacterial counts in infected primary canals. Chlorhexidine (solution and gel) can be considered a good alternative to sodium hypochlorite in irrigation root canals of primary teeth.

目的:次氯酸钠不能完全清除根管内的粪肠球菌。因此，本研究旨在评价氯己定凝胶和溶液在消除原牙感染根管内细菌计数方面的作用。材料与方法选取27例健康儿童的75颗乳牙，分为5组:1组2%氯己定溶液，2组2%超声活化氯己定溶液，3组2%氯己定凝胶，4组2%超声活化氯己定凝胶，5组5.25%次氯酸钠溶液。冲洗前进行细菌初步涂片检查(S1)。用31号灌洗针灌洗根管，灌洗量为7 ml，灌洗激活2个周期(20 s)。灌洗后进行最后的细菌涂片(S2)。结果两组间厌氧菌菌落计数小数对数的平均变化百分比差异无统计学意义，而好氧菌菌落计数的变化百分比差异有统计学意义。对好氧菌:CHx 2%溶液活化优于CHx 2%和NaOCl 5.25%溶液，CHx 2%凝胶活化优于CHx 2%溶液，CHx 2%凝胶活化优于CHx 2%和NaOCl 5.25%溶液。结论所有冲洗液均能有效清除感染根管的细菌计数。氯己定(溶液和凝胶)是替代次氯酸钠用于乳牙根管冲洗的好方法。
{"title":"Evaluation of antibacterial efficacy of ultrasonic-activated and inactivated chlorhexidine (solution and gel) in infected root canals of primary anterior teeth","authors":"Rahaf Kharsa ,&nbsp;Mohanad Laflouf ,&nbsp;Taissir Albouni ,&nbsp;Hasan Alzoubi","doi":"10.1016/j.pdj.2023.03.003","DOIUrl":"10.1016/j.pdj.2023.03.003","url":null,"abstract":"<div><h3>Objectives</h3><p>Sodium hypochlorite is not able to completely eliminate <span><em>Enterococcus faecalis</em></span><span><span> inside root canals. Therefore, this study aimed to evaluate chlorhexidine gel and solution in eliminating bacterial counts within infected root canals of primary </span>anterior teeth.</span></p></div><div><h3>Materials and methods</h3><p>This study included 75 primary anterior teeth in 27 healthy children and it was divided into five groups: Group 1: Chlorhexidine 2% solution, Group 2: Chlorhexidine 2% solution activated by ultrasonic, Group 3: Chlorhexidine 2% gel, Group 4: Chlorhexidine 2% gel activated by ultrasonic, and Group 5: Sodium hypochlorite solution 5.25%. The preliminary smear for bacterial study (S1) was taken before irrigation. The root canals were irrigated in a quantity of 7 ml using a 31-gauge irrigation needle, and irrigant activation was 2 cycles (20 s). The final smear for bacterial study (S2) was taken after irrigation.</p></div><div><h3>Results</h3><p>There were no statistically differences in the mean percentage change in the decimal logarithm of the anaerobic bacterial colony count, but statistically differences were found for aerobic bacteria. For aerobic bacteria: CHx 2% solution activated better than CHx 2% and NaOCl 5.25% solutions, CHx 2% gel better than CHx 2% solution, CHx 2% gel activated better than CHx 2% and NaOCl 5.25% solutions.</p></div><div><h3>Conclusion</h3><p><span>All irrigation solutions used are effective in eliminating bacterial counts in infected primary canals. Chlorhexidine (solution and gel) can be considered a good alternative to sodium hypochlorite in irrigation root canals of </span>primary teeth.</p></div>","PeriodicalId":19977,"journal":{"name":"Pediatric Dental Journal","volume":"33 2","pages":"Pages 93-101"},"PeriodicalIF":0.8,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48809333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
类型
全部 化学•材料 生命科学 医学 物理 工程技术 环境•农林 材料科学 地球科学 法学 管理学 化学 环境科学与生态学 计算机科学 教育学 经济学 农林科学 人文科学 生物学 数学 物理与天体物理 心理学 综合性期刊 其他 工业工程 理学 历史学 农学 文学 信息工程
数据库
全部 ACS Publications Elsevier ieeexplore Springer The Royal Society of Chemistry Wiley
期刊
Pediatric Dental Journal
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
﹀
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们：info@booksci.cn
Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1