Preventive medicine最新文献_第9页

Reprint of: The effects of switching to the standardized research electronic cigarette in people with HIV who smoke in the United States 转载：在美国，对吸烟的艾滋病毒感染者改用标准化研究电子烟的影响。

IF 3.2 2区医学 Q1 MEDICINE, GENERAL & INTERNAL

Preventive medicine

Pub Date : 2025-08-27 DOI: 10.1016/j.ypmed.2025.108389

Patricia A. Cioe , William V. Lechner , Garrett S. Stang , Christopher W. Kahler , Karen T. Tashima , Thomas Eissenberg , Jennifer W. Tidey

Objective

People with HIV (PWH) who smoke and report ambivalence about quitting may benefit from switching to non-combusted nicotine products. This pilot study examined the effects of providing the NIDA standardized research electronic cigarette (SREC) on smoking behaviors and inflammatory biomarkers in PWH.

Methods

Thirty-five participants in the United States were enrolled from April 2022 to January 2024 (Mean age 54.4 [13.2] years, 30.1 % female, 62.9 % White) and randomized to SREC provision (n = 17) or usual brand control (n = 18). SREC participants were asked to substitute tobacco-flavor pod-type SRECs for their combustible cigarettes. SREC use and cigarette use were assessed weekly for 6 weeks. Serum inflammatory biomarkers were measured at baseline and week 6.

Results

The effect of condition on cigarettes per day (CPD) during the 6-week period was significant, B = −5.68, 95 % CI = −10.25, −1.11: CPD were reduced by 42.7 % in the SREC condition versus 17.3 % in the control condition. Participants in the SREC condition reported significantly lower urge to smoke at week 6 compared to those in control, (B = −17.05, 95 % CI = -27.15, −6.95). One (5.9 %) participant reported that they transitioned completely from CCs to SREC at week 6. Significant decreases in inflammatory biomarkers were not observed.

Conclusions

Participants who were provided the SREC, compared to those in the control condition, smoked fewer CPD and had reduced urge to smoke. However, dual use was the most common outcome, indicating that additional support may be needed to improve the likelihood of complete transition from CCs to noncombustible products.

目的：吸烟并对戒烟有矛盾心理的HIV感染者（PWH）可能会从转向非燃烧尼古丁产品中受益。本初步研究考察了提供NIDA标准化研究电子烟（SREC）对PWH吸烟行为和炎症生物标志物的影响。方法：从2022年4月到2024年1月，在美国招募了35名参与者（平均年龄54.4[13.2]岁，女性30.1%，白人62.9%），随机分为SREC组（n = 17）和常规品牌组（n = 18）。SREC参与者被要求用烟草味豆荚型SREC代替他们的可燃香烟。每周评估SREC使用情况和香烟使用情况，持续6周。在基线和第6周测量血清炎症生物标志物。结果：6周时间内，状态对吸烟者日吸烟量（CPD）的影响显著，B = -5.68, 95% CI = -10.25, -1.11: SREC组吸烟量减少42.7%，对照组减少17.3%。与对照组相比，SREC组在第6周报告的吸烟冲动显著降低（B = -17.05, 95% CI = -27.15, -6.95）。一名（5.9%）参与者报告他们在第6周完全从cc过渡到SREC。炎症生物标志物未见显著下降。结论：与对照组相比，提供SREC的参与者吸烟的CPD减少，吸烟的冲动也减少。然而，双重用途是最常见的结果，这表明可能需要额外的支持来提高从CCs完全过渡到不可燃产品的可能性。

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引用次数: 0

Prospective association of internet gaming disorder with subsequent first suicidal attempt: A large-scale school-based study of Chinese adolescents 网络游戏障碍与随后的第一次自杀企图的前瞻性关联：一项针对中国青少年的大规模学校研究

IF 3.2 2区医学 Q1 MEDICINE, GENERAL & INTERNAL

Preventive medicine

Pub Date : 2025-08-27 DOI: 10.1016/j.ypmed.2025.108396

Pu Peng , Zhangming Chen , Silan Ren , Yudiao Liang , Youguo Tan , Xiaogang Chen , Jinsong Tang , Yanhui Liao

Objectives

While Internet Gaming Disorder (IGD) is a known risk factor for suicidal ideation, longitudinal evidence linking it to suicidal attempt remains scarce. This study investigates whether IGD severity independently predicts first-onset suicidal attempt in adolescents.

Methods

A school-based cohort of 87,390 Chinese adolescents (baseline age: 14.2 ± 1.5 years) was followed for one year (2022−2023). The severity of IGD was assessed using the Internet Gaming Disorder Scale-Short Form (IGDS9-SF). The primary analysis utilized multivariable logistic regression to examine the association between the continuous IGDS9-SF score and incident suicidal attempts, adjusting for demographics, mental health symptoms, and baseline suicidal ideation. Sensitivity analyses included examining categorical IGD status, individual symptom contributions, non-linearity testing, and E-value calculation.

Results

A total of 6620 (7.6 %) adolescents reported an incident suicidal attempt. Each one-point increase in the IGDS9-SF score raised the odds of a first suicidal attempt by 2 % (Adjusted Odds Ratio = 1.02, 95 % CI = 1.02–1.03). The association was robust across all sensitivity analyses, demonstrating a linear trend and resilience to unmeasured confounding (E-value ≥2.24).

Conclusions

IGD severity is an independent, dose-dependent associated factor for suicidal attempt in adolescents. Measuring IGD severity might be a valuable strategy for identifying adolescents at risk.

虽然网络游戏障碍（IGD）是一个已知的自杀意念风险因素，但将其与自杀企图联系起来的纵向证据仍然很少。本研究调查IGD严重程度是否独立预测青少年首次自杀企图。方法以学校为基础，对87,390名中国青少年（基线年龄：14.2±1.5岁）进行为期一年（2022 - 2023年）的随访。IGD的严重程度采用网络游戏障碍量表（IGDS9-SF）进行评估。初步分析利用多变量逻辑回归来检验连续IGDS9-SF评分与事件自杀企图之间的关系，调整人口统计学、心理健康症状和基线自杀意念。敏感性分析包括检查IGD的分类状态、个体症状贡献、非线性检验和e值计算。结果共有6620名（7.6%）青少年报告有自杀未遂行为。IGDS9-SF评分每增加1分，第一次自杀企图的几率增加2%（调整优势比= 1.02,95% CI = 1.02 - 1.03）。在所有敏感性分析中，这种关联都是稳健的，显示出线性趋势和对未测量混杂因素的恢复力（e值≥2.24）。结论sigd严重程度是青少年自杀企图的独立、剂量依赖性相关因素。测量IGD的严重程度可能是识别青少年风险的一个有价值的策略。

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引用次数: 0

Suicide trends and patterns in young adults across global regions and selected major countries worldwide from the World Health Organization mortality database, 2001–2020 2001-2020年世界卫生组织死亡率数据库中全球各区域和选定主要国家青年的自杀趋势和模式

IF 3.2 2区医学 Q1 MEDICINE, GENERAL & INTERNAL

Preventive medicine

Pub Date : 2025-08-26 DOI: 10.1016/j.ypmed.2025.108397

Minjae Choi , Sujeong Yu , Hanul Park , Joshua Kirabo Sempungu , Joon Hee Han , Eun Hae Lee , Yo Han Lee

Objective

We aimed to analyze trends and patterns of suicide among young adults worldwide, 2001–2020.

Methods

We used the World Health Organization Mortality Database to extract suicide deaths for individuals aged 20–39 years from 55 countries with valid and medium/high-quality data, 2001–2020. Suicide rates were calculated by sex, age group, and suicide method across global regions and countries. We conducted a joinpoint regression analysis to identify trends and changes in suicide rates.

Results

Marked geographical disparities were found in suicide trends by sex and method. In the Americas, suicide rates recently increased across all subregions, particularly in the North American region. In contrast, most European subregions showed decreasing trends in suicide rates in both males and females, except for North Europe. In Asia, suicide trends varied across subregions, with marked reductions in Central Asia among males and fluctuations in East Asia among females. Hanging was the most commonly used method across all countries, except in the US, where firearms were more used, particularly among males. Other major methods, such as poisoning and gas poisoning, showed changes in trends.

Conclusions

Suicide trends among young adults varied by sex, method, and country, with concerning increases or persistently high rates in some countries.

目的分析2001-2020年全球年轻人自杀的趋势和模式。方法使用世界卫生组织死亡率数据库提取2001-2020年55个国家20-39岁人群的有效和中/高质量自杀死亡数据。自杀率是根据全球各地区和国家的性别、年龄组和自杀方式来计算的。我们进行了联结点回归分析，以确定自杀率的趋势和变化。结果自杀倾向在性别和自杀方式上存在明显的地域差异。在美洲，所有分区域的自杀率最近都有所上升，特别是在北美区域。相比之下，除北欧外，大多数欧洲分区域的男性和女性自杀率均呈下降趋势。在亚洲，各分区域的自杀趋势各不相同，中亚男性的自杀趋势明显减少，东亚女性的自杀趋势有所波动。绞刑是所有国家中最常用的方法，除了美国，在美国，枪支的使用更多，尤其是在男性中。其他主要的自杀方式，如中毒和煤气中毒，也呈现出变化趋势。结论：年轻人的自杀趋势因性别、方法和国家而异，在一些国家自杀率有所上升或持续居高不下。

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引用次数: 0

Association of sustained extremely low income and income decrease with the risk of Parkinson's disease: A population-based nationwide cohort study in Korea 持续极低收入和收入减少与帕金森病风险的关系：韩国一项基于人群的全国队列研究

IF 3.2 2区医学 Q1 MEDICINE, GENERAL & INTERNAL

Preventive medicine

Pub Date : 2025-08-25 DOI: 10.1016/j.ypmed.2025.108394

Seo Yeon Yoon , Kyungdo Han , Kyu-Na Lee , Jee Hyun Suh , Ga Eun Nam

Objective

Previous studies on the association between income and Parkinson's disease assessed income status at a single time point, without considering changes over time. This study aimed to evaluate the longitudinal association between various income dynamics and the risk of Parkinson's disease.

Methods

We used the Korean National Health Insurance Service data, enrolling 2,644,550 individuals who participated in the 2012 National Health Screening Program. The national health insurance premium was used as a proxy measure of income, with four levels (quartile 1 [low] to 4 [high]). Additionally, Medical Aid was classified as extremely low-income. Parkinson's disease was defined using the ICD-10 code (G20) and the rare intractable disease registration code (V124). Cox proportional hazards models were used to assess the longitudinal association between income status and Parkinson's disease rate.

Results

During the study period, the incidence rate of Parkinson's disease was 27.13 per 100,000 person-years. A dose-response association between the cumulative number of years in the extremely low-income status and Parkinson's disease rate was identified (P for trend <0.001). A decrease in income from 2008 to 2012 to extremely low-income from quartile 1 (HR = 2.19, 95 % CI 1.55, 3.09), quartile 2 (HR = 2.56, 95 % CI 1.75, 3.74), or quartile 3 (HR = 2.20, 95 % CI 1.24, 3.88) was associated with more than a two-fold increased Parkinson's disease rate compared to individuals with sustained income status.

Conclusions

Individuals with sustained extremely low income over 5 consecutive years and those who experienced a decrease in income to this status were at a significantly higher rate of developing Parkinson's disease.

目的以往关于收入与帕金森病关系的研究只评估了一个时间点的收入状况，而没有考虑随时间的变化。本研究旨在评估不同收入动态与帕金森病风险之间的纵向关联。方法：我们使用韩国国民健康保险服务的数据，纳入了参加2012年国家健康筛查计划的2,644,550人。国家健康保险费被用作收入的替代衡量标准，分为四个等级（四分位数1[低]至4[高]）。此外，医疗援助被列为极低收入。使用ICD-10代码（G20）和罕见难治性疾病登记代码（V124）对帕金森病进行定义。采用Cox比例风险模型评估收入状况与帕金森病发病率之间的纵向关联。结果在研究期间，帕金森病的发病率为27.13 / 10万人/年。发现极低收入状态的累积年数与帕金森病发病率之间存在剂量反应相关性（P代表趋势<；0.001）。从2008年到2012年，收入从四分位数1 （HR = 2.19, 95% CI 1.55, 3.09）、四分位数2 （HR = 2.56, 95% CI 1.75, 3.74）或四分位数3 （HR = 2.20, 95% CI 1.24, 3.88）下降到极低收入者，与持续收入状况的个体相比，帕金森病发病率增加了两倍以上。结论连续5年以上持续收入极低的个体和收入下降到这一水平的个体患帕金森病的几率明显较高。

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引用次数: 0

Maintaining healthy lifestyle behaviours in the era of social media: Challenges and solutions 在社交媒体时代保持健康的生活方式：挑战和解决方案

IF 3.2 2区医学 Q1 MEDICINE, GENERAL & INTERNAL

Preventive medicine

Pub Date : 2025-08-24 DOI: 10.1016/j.ypmed.2025.108395

Jean-Philippe Chaput , Allana G. LeBlanc

Objective

To examine the dual role of social media in influencing lifestyle behaviours relevant to chronic disease prevention and to propose strategies that align digital environments with public health objectives.

Methods

This commentary synthesizes recent evidence on the associations between social media use and health behaviours, including physical activity, nutrition, sleep, and sedentary time. It draws on research from public health, behavioural science, and digital media studies to highlight both risks and opportunities.

Results

Evidence shows that prolonged and unregulated social media engagement contributes to increased sedentary time, sleep disruption, poor dietary choices, exposure to targeted marketing of unhealthy products, unrealistic body ideals, and health misinformation. Conversely, social media can be harnessed to promote behaviour change through scalable interventions such as social support, self-monitoring, and goal setting.

Conclusions

Addressing the challenges posed by social media requires coordinated, multi-level strategies. These include redesigning digital environments with health-promoting defaults, regulating harmful commercial exposures, leveraging platforms for evidence-based health promotion, strengthening digital literacy, and introducing school-based smartphone restrictions. Aligning platform design and governance with public health goals is essential to mitigating risks, supporting healthy behaviours, and improving population health outcomes.

目的研究社交媒体在影响与慢性病预防相关的生活方式行为方面的双重作用，并提出使数字环境与公共卫生目标保持一致的战略。这篇评论综合了最近关于社交媒体使用与健康行为（包括身体活动、营养、睡眠和久坐时间）之间关系的证据。它借鉴了公共卫生、行为科学和数字媒体研究方面的研究，以突出风险和机遇。结果有证据表明，长时间和不受监管的社交媒体参与会导致久坐时间增加、睡眠中断、不良饮食选择、接触不健康产品的定向营销、不切实际的身体理想和健康错误信息。相反，社交媒体可以通过社会支持、自我监控和目标设定等可扩展的干预措施来促进行为改变。应对社交媒体带来的挑战需要协调的、多层次的战略。这些措施包括重新设计具有促进健康默认值的数字环境，规范有害的商业暴露，利用基于证据的健康促进平台，加强数字素养，以及引入基于学校的智能手机限制。使平台设计和治理与公共卫生目标保持一致，对于减轻风险、支持健康行为和改善人口健康结果至关重要。

{"title":"Maintaining healthy lifestyle behaviours in the era of social media: Challenges and solutions","authors":"Jean-Philippe Chaput , Allana G. LeBlanc","doi":"10.1016/j.ypmed.2025.108395","DOIUrl":"10.1016/j.ypmed.2025.108395","url":null,"abstract":"<div><h3>Objective</h3><div>To examine the dual role of social media in influencing lifestyle behaviours relevant to chronic disease prevention and to propose strategies that align digital environments with public health objectives.</div></div><div><h3>Methods</h3><div>This commentary synthesizes recent evidence on the associations between social media use and health behaviours, including physical activity, nutrition, sleep, and sedentary time. It draws on research from public health, behavioural science, and digital media studies to highlight both risks and opportunities.</div></div><div><h3>Results</h3><div>Evidence shows that prolonged and unregulated social media engagement contributes to increased sedentary time, sleep disruption, poor dietary choices, exposure to targeted marketing of unhealthy products, unrealistic body ideals, and health misinformation. Conversely, social media can be harnessed to promote behaviour change through scalable interventions such as social support, self-monitoring, and goal setting.</div></div><div><h3>Conclusions</h3><div>Addressing the challenges posed by social media requires coordinated, multi-level strategies. These include redesigning digital environments with health-promoting defaults, regulating harmful commercial exposures, leveraging platforms for evidence-based health promotion, strengthening digital literacy, and introducing school-based smartphone restrictions. Aligning platform design and governance with public health goals is essential to mitigating risks, supporting healthy behaviours, and improving population health outcomes.</div></div>","PeriodicalId":20339,"journal":{"name":"Preventive medicine","volume":"199 ","pages":"Article 108395"},"PeriodicalIF":3.2,"publicationDate":"2025-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144902918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between midlife intake of ultra-processed foods and later-life subjective cognitive complaints: Evidence from the new York University women's health study 中年摄入超加工食品与晚年主观认知抱怨之间的关系：来自纽约大学妇女健康研究的证据

IF 3.2 2区医学 Q1 MEDICINE, GENERAL & INTERNAL

Preventive medicine

Pub Date : 2025-08-21 DOI: 10.1016/j.ypmed.2025.108390

Kejia Zhang , Fen Wu , Tess V. Clendenen , Yelena Afanasyeva , Yian Gu , Karen L. Koenig , Anne Zeleniuch-Jacquotte , Yu Chen

Objective

Research into risk factors for subjective cognitive complaints (SCCs) may offer insight into the etiology and prevention of Alzheimer's disease. Ultra-processed foods (UPFs) contain food additives that improve palatability and processed raw materials. Evidence is limited on the role of mid-life UPF intake in the development of late-life SCCs.

Methods

We included 5119 participants who responded to the 2018 or 2020 follow-up of the New York University Women's Health Study, a prospective cohort of 14,274 women recruited in New York City, United States, in 1985–91. Data on diet were collected at baseline using a validated modified Block food frequency questionnaire. Energy-adjusted total intake of UPFs and subgroups of UPFs, defined following the nova guidelines, were estimated using the residual method.

Results

The odds ratios (ORs) and 95 % confidence intervals (CIs) for reporting ≥2 SCCs were 1.15 (0.94–1.39), 1.06 (0.87–1.30), 1.20 (0.99–1.46), and 1.24 (1.02–1.51) for women in the 2nd, 3rd, 4th, and 5th quintiles of energy-adjusted UPF intake, respectively, compared to those in the bottom quintile (p-trend = 0.02). The associations were similar in sensitivity analyses using Multiple Imputation and Inverse Probability Weighting to account for potential selection bias.

Conclusions

Higher UPF intakes in midlife were associated with higher odds of late-life SCCs in women.

目的研究主观认知主诉（SCCs）的危险因素，为阿尔茨海默病的病因和预防提供新的思路。超加工食品（upf）含有食品添加剂，可改善适口性和加工原料。关于中年UPF摄入在晚期SCCs发展中的作用的证据有限。方法：我们纳入了5119名参与者，他们对纽约大学女性健康研究的2018年或2020年随访做出了回应，这是一个1985-91年在美国纽约市招募的14274名女性的前瞻性队列。饮食数据在基线时使用经过验证的改良Block食物频率问卷收集。根据nova指南定义的upf和upf亚组的能量调整总摄入量使用残差法进行估计。结果能量调节UPF摄入第二、三、四、五分位数女性报告≥2个SCCs的优势比（ORs）和95%可信区间（ci）分别为1.15（0.94-1.39）、1.06（0.87-1.30）、1.20（0.99-1.46）和1.24(1.02-1.51)，与最低五分位数女性相比（p趋势= 0.02）。在使用多重输入和逆概率加权来解释潜在的选择偏差的敏感性分析中，这些关联是相似的。结论较高的UPF摄入量与女性晚年SCCs的发生率相关。

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引用次数: 0

Inequities in food security by sexual orientation in the United States 美国性取向导致的食品安全不平等

IF 3.2 2区医学 Q1 MEDICINE, GENERAL & INTERNAL

Preventive medicine

Pub Date : 2025-08-20 DOI: 10.1016/j.ypmed.2025.108391

Alexandra Balshi , John P. Dempsey , Hannah R. Thompson , Mary W. Montgomery

Objective

To determine if sexual minority (gay, lesbian, bisexual, or another [LGB+] sexual orientation) identity independently contributes to food insecurity while accounting for other social drivers of health (SDoH) like race, education, employment, supplemental nutrition assistance program (SNAP) participation, and mental illness.

Methods

We performed multivariate logistic regression of 2019–2023 National Health Interview Surveys to determine any relationship between LGB+ identity and 30-day food security scale responses.

Results

We included 130,656 participants, representing 235,728,318 Americans by weighted sampling. Among those eligible, there was no difference in SNAP utilization between LGB+ and heterosexual individuals (odds ratio: 1.12, 95 % confidence interval: 0.97–1.30). However, LGB+ individuals had 1.53 times higher odds of very low food security (95 % confidence interval: 1.31–1.79) even after adjusting for SDoH and mental illness.

Conclusion

Despite similar SNAP enrollment, LGB+ individuals remain disproportionately food insecure, suggesting that structural or systemic barriers not addressed through federal food assistance programs contribute to elevated risk.

目的确定性少数群体（男同性恋、女同性恋、双性恋或其他[LGB+]性取向）身份是否独立导致粮食不安全，同时考虑种族、教育、就业、补充营养援助计划（SNAP）参与和精神疾病等其他社会健康驱动因素。方法对2019-2023年全国健康访谈调查进行多元logistic回归，以确定LGB+身份与30天食品安全量表反应之间的关系。结果我们通过加权抽样纳入130,656名参与者，代表235,728,318名美国人。在符合条件的人群中，LGB+和异性恋个体在SNAP使用方面没有差异（优势比：1.12,95%可信区间：0.97-1.30）。然而，即使在调整了SDoH和精神疾病之后，LGB+个体的食物安全非常低的几率（95%置信区间：1.31-1.79）高出1.53倍。尽管有类似的SNAP招募，LGB+个体仍然不成比例地保持粮食不安全，这表明没有通过联邦食品援助计划解决的结构性或系统性障碍导致风险升高。

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引用次数: 0

Electronic cigarettes and pregnancy: A social media content analysis 电子烟与怀孕：一项社交媒体内容分析。

IF 3.2 2区医学 Q1 MEDICINE, GENERAL & INTERNAL

Preventive medicine

Pub Date : 2025-08-13 DOI: 10.1016/j.ypmed.2025.108387

Grace Kong, Rachel R. Ouellette, Amanda de la Noval, Christina N. Kyriakos, Vanessa Ponte, Elise E. DeVito

Objective

Electronic cigarette (e-cigarette) use during pregnancy is a polarizing and complex public health topic. We examined social media content on e-cigarette use during pregnancy.

Methods

We content analyzed 170 TikTok posts about e-cigarettes and pregnancy in 2023. We coded message valence (anti-, pro-, mixed/unclear/neutral), messenger characteristics (age, gender, pregnancy status, healthcare provider status, e-cigarette and cigarette use), geographic origin, and engagement metrics (likes, favorites, shares, downloads, comments, followers). We assessed whether engagement and message valence differed by messenger and post characteristics using Chi-Square and Kruskal-Wallis tests.

Results

Posts included 55 % (n = 93) anti-, 32.4 % (n = 55) mixed/unclear/neutral, and 12.9 % (n = 22) pro-e-cigarette use during pregnancy messages. Messenger characteristics included 90.6 % (n = 144) female, 53.5 % (n = 85) 18 to 30 years old, 40.9 % (n = 65) pregnant, 7.5 % (n = 12) healthcare providers. Geographic origin included 66.5 % (n = 113) from the United States and 22.9 % (n = 39) from the United Kingdom. Engagement was high, with some videos receiving over 2 million “plays” and 500 thousand “likes.” Posts by healthcare providers and messengers over 45 years old had more followers (ps < 0.001). Posts with messengers who quit e-cigarettes, from the US, and 18–45 years old were more likely to contain anti-e-cigarette content, whereas posts from the United Kingdom were more likely to have pro-e-cigarette content (ps ≤ 0.001).

Conclusions

A wide range of content on e-cigarette use and pregnancy was observed on TikTok. Future research is needed to understand how pregnant individuals navigate this content. Healthcare providers may be effective messengers for promoting e-cigarette cessation during pregnancy on social media.

目的：孕期使用电子烟是一个两极分化且复杂的公共卫生话题。我们研究了怀孕期间使用电子烟的社交媒体内容。方法：我们对2023年TikTok上170篇关于电子烟和怀孕的帖子进行了内容分析。我们对信息的价值（反对、支持、混合/不明确/中立）、信息特征（年龄、性别、怀孕状况、医疗服务提供者状况、电子烟和香烟使用）、地理来源和参与指标（喜欢、收藏、分享、下载、评论、关注者）进行了编码。我们使用卡方检验和Kruskal-Wallis检验来评估参与和信息效价是否因信使和帖子特征而不同。结果:文章包括55 % (n = 93)反,32.4 % (n = 55)混合/不清楚/中性,和12.9 % (n = 22)怀孕期间pro-e-cigarette使用消息。信使特征包括90.6 % (n = 144)女,53.5 % (n = 85)18到30 岁40.9 % (n = 65)怀孕了,7.5 % (n = 12)卫生保健提供者。地理来源包括66.5 % （n = 113）来自美国，22.9 % （n = 39）来自英国。用户参与度很高，一些视频获得了超过200万次“播放”和50万次“赞”。结论：在TikTok上观察到有关电子烟使用和怀孕的广泛内容。未来的研究需要了解孕妇如何浏览这些内容。医疗保健提供者可能是在社交媒体上宣传怀孕期间戒烟电子烟的有效信使。

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引用次数: 0

Adverse childhood experiences, resilience, and substance use during early pregnancy 不良的童年经历、恢复力和怀孕早期的药物使用。

IF 3.2 2区医学 Q1 MEDICINE, GENERAL & INTERNAL

Preventive medicine

Pub Date : 2025-08-13 DOI: 10.1016/j.ypmed.2025.108388

Kelly C. Young-Wolff , Mariah S. Wood , Sara R. Adams , Monique B. Does , Deborah Ansley , Carley Castellanos , Maria T. Koshy , Carey R. Watson

Objective

Adverse childhood experiences (ACEs) are common risk factors for unhealthy behaviors and poor health outcomes throughout the life course, but their relationship with prenatal substance use is understudied. This retrospective cohort study included 44,284 patients with pregnancies between January 1, 2022, and June 28, 2024, in a large healthcare system in Northern California, United States of America with universal screening for ACEs, resilience, and substance use during early pregnancy.

Methods

Multivariable regression models examined the relationship between ACEs and prenatal substance use and tested whether resilience moderated these associations.

Results

Pregnant individuals with a greater number of ACEs had lower resilience, were younger, more likely to be Black, Non-Hispanic White, or Hispanic, and live in an area with greater neighborhood deprivation. In adjusted models, compared to those without ACEs, those with ACEs had a higher adjusted prevalence of prenatal alcohol use, cannabis use, nicotine use, pharmaceutical opioid use, stimulant use, and multiple substance use. Low resilience was independently associated with an increased prevalence of prenatal substance use.

Conclusions

Results indicate that routine screening for ACEs may help identify pregnant individuals at risk for prenatal substance use, allowing for earlier linkage to resources and potentially improved maternal and child outcomes.

目的：不良童年经历（Adverse childhood experiences）是一生中不健康行为和不良健康结果的常见危险因素，但其与产前药物使用的关系尚不清楚。这项回顾性队列研究纳入了44284名在2022年1月1日至2024年6月28日期间怀孕的患者，这些患者来自美国北加州的一个大型医疗保健系统，对妊娠早期的不良童年经历、恢复能力和药物使用进行了普遍筛查。方法：多变量回归模型检验了不良童年经历与产前物质使用之间的关系，并测试了弹性是否调节了这些关联。结果：童年不良经历较多的孕妇适应力较低，年龄更小，更可能是黑人、非西班牙裔白人或西班牙裔，并且生活在更严重的邻里剥夺地区。在调整后的模型中，与没有不良童年经历的人相比，有不良童年经历的人在产前饮酒、大麻使用、尼古丁使用、阿片类药物使用、兴奋剂使用和多种物质使用方面的调整患病率更高。低恢复力与产前药物使用的流行率增加独立相关。结论：结果表明，对不良童年经历的常规筛查可能有助于识别有产前药物使用风险的孕妇，从而允许更早地与资源联系，并可能改善孕产妇和儿童的结局。

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引用次数: 0

Association between an active lifestyle and reduced incidence of obesity-related cancers in the Seguimiento Universidad de Navarra cohort Seguimiento university de Navarra队列中积极的生活方式与减少肥胖相关癌症发病率之间的关系

IF 3.2 2区医学 Q1 MEDICINE, GENERAL & INTERNAL

Preventive medicine

Pub Date : 2025-08-08 DOI: 10.1016/j.ypmed.2025.108386

Maite Bastyr-Diego , Maria Barbería-Latasa , Maria Olmedo , Alfredo Gea , Maira Bes-Rastrollo , Miguel Ángel Martínez-González , Estefania Toledo

Objective

To assess whether physical activity, sedentary behavior, and an active lifestyle score, combining physical activity and sedentary behavior, are associated with developing obesity-related cancers (ORCs).

Methods

From 1999 through 2022, a cohort of Spanish university graduates was followed using biennial questionnaires collecting data on sociodemographic characteristics, clinical diagnoses, and lifestyle factors. We used a previously validated questionnaire to assess physical and sedentary activities (television watching+sitting time), from which we estimated an eight-item active lifestyle score. Cancer incidence was confirmed with medical records and the National Death Index. Multivariable-adjusted hazard ratios (HRs) were estimated with Cox regression models.

Results

Higher adherence to the active lifestyle score nearly halved the risk of ORCs (HR high vs. low 0.45 (95 %CI 0.27–0.73)). The HR in quartile four (Q4) of leisure-time physical activity was 0.54 (95 %CI 0.37–0.80) compared to Q1. The HR per +1-point increase in the score was 0.88 (95 %CI 0.81–0.95). No significant association was observed between television watching and ORCs risk.

Conclusions

A higher active lifestyle score was associated with a decreased risk of ORCs. These findings may aid public health organizations in refining recommendations in ORC prevention to include interventions focused on combining increased physical activity and lowered sedentary behavior.

目的：评估身体活动、久坐行为和积极生活方式评分（结合身体活动和久坐行为）是否与肥胖相关癌症（ORCs）的发生有关。方法：从1999年到2022年，对一组西班牙大学毕业生进行了两年一次的问卷调查，收集了社会人口统计学特征、临床诊断和生活方式因素的数据。我们使用先前验证过的问卷来评估身体和久坐不动的活动（看电视+坐着的时间），从中我们估计了8项积极生活方式的得分。癌症发病率通过医疗记录和国家死亡指数得到确认。采用Cox回归模型估计多变量校正风险比（hr）。结果：坚持积极生活方式得分越高，发生ORCs的风险几乎减半（HR高比低0.45(95 %CI 0.27-0.73)）。与Q1相比，第四分位数（Q4）的休闲时间身体活动的HR为0.54（95 %CI 0.37-0.80）。每增加1分，HR为0.88（95 %CI 0.81-0.95）。没有观察到电视观看与ORCs风险之间的显著关联。结论：积极生活方式评分的增加与ORCs风险的降低相关。这些发现可能有助于公共卫生组织完善ORC预防建议，包括集中于增加体育活动和减少久坐行为的干预措施。

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