Preventive medicine最新文献_第9页

Cross-sectional associations of gender identity and sexual orientation, with co-occurrence and clustering of health-related behaviours among British adolescents: Millennium cohort study 英国青少年中性别认同和性取向与健康相关行为的共同发生和聚类的横截面关联：千年队列研究。

IF 4.3 2区医学 Q1 MEDICINE, GENERAL & INTERNAL

Preventive medicine

Pub Date : 2024-07-22 DOI: 10.1016/j.ypmed.2024.108084

Luiza I.C. Ricardo , Andrea D. Smith , Kathryn R. Hesketh , Yanaina Chavez-Ugalde , Eun-Young Lee , Esther M.F. van Sluijs

Purpose

We examined whether gender identity and sexual orientation were associated with seven health-related behaviours, and with co-occurrence and clustering of these behaviours among British adolescents.

Methods

Millennium Cohort Study (age 17 wave) provided data on the exposures, gender identity (male, female, genderqueer) and sexual orientation (heterosexual, bisexual, gay or lesbian, or other), and seven self-reported health-related behaviours (binge drinking, drug use, no consumption of breakfast, no consumption of fruits or vegetables, physical inactivity, poor sleep, and smoking or vaping). Poisson regressions examined associations between the exposures and single behaviours (reporting prevalence ratios (PRs)); and multinomial logistic regressions were used for behavioural cumulative co-occurrence score (reporting PRs). Cluster patterns were identified using Ward's agglomerative hierarchical cluster analysis while associations with cluster membership were performed using logistic regressions (reporting odds ratios (ORs)).

Results

Our sample included 6022 adolescents (55.4% female, 1.5% genderqueer, 11.6% non-heterosexual). Adolescents who identified as genderqueer had the highest prevalence of not eating breakfast (PR: 60.5% [95%CI 48.4–71.4]) and poor sleep (68.7% [95%CI 55.6–79.3]). Those who identified as bisexual had a higher PR of co-occurring behaviours (2.46 [95%CI 1.39–4.27]). Among the three clusters identified (1: Multiple risk behaviours; 2: Physical inactivity and binge drinking; 3: Poor diet and physical inactivity), adolescents who identified as genderqueer or other sexual orientation showed the highest prevalence in cluster 3.

Conclusion

Gender and sexual minority British adolescents showed a higher prevalence of risky health-related behaviours, and higher risk of co-occurring behaviours. Physical inactivity and poor diet behaviours commonly clustered together for these groups.

目的：我们研究了在英国青少年中，性别认同和性取向是否与七种与健康有关的行为相关，以及这些行为的共同发生和聚类情况：千禧年队列研究（17 岁波）提供了有关暴露、性别认同（男性、女性、变性者）和性取向（异性恋、双性恋、男同性恋或女同性恋或其他）以及七种自我报告的健康相关行为（酗酒、吸毒、不吃早餐、不吃水果或蔬菜、缺乏运动、睡眠不足以及吸烟或吸食毒品）的数据。泊松回归检验了暴露与单一行为（报告流行率 (PRs)）之间的关联；多项式逻辑回归用于行为累积共同发生得分（报告流行率 (PRs)）。使用沃德聚类分层聚类分析确定聚类模式，使用逻辑回归（报告几率比（ORs））分析与聚类成员资格的关联：我们的样本包括 6022 名青少年（55.4% 为女性，1.5% 为异性，11.6% 为非异性恋）。被认定为性别同异的青少年不吃早餐（PR：60.5% [95%CI 48.4-71.4]）和睡眠质量差（68.7% [95%CI 55.6-79.3]）的发生率最高。那些被认定为双性恋的人有更高的并发行为 PR（2.46 [95%CI 1.39-4.27]）。在已确定的三个群组（1：多种危险行为；2：缺乏运动和酗酒；3：不良饮食习惯和缺乏运动）中，在群组 3 中，被确定为性别少数或其他性取向的青少年发病率最高：结论：在性别和性取向上属于少数群体的英国青少年的健康相关危险行为发生率较高，同时出现并发行为的风险也较高。在这些群体中，缺乏运动和不良饮食行为通常集中在一起。

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引用次数: 0

The cross-sectional association between dietary total, animal, and plant-based protein intake and the prevalence and severity of depressive symptoms in Dutch adults with type 2 diabetes: The Hoorn Diabetes Care System cohort 荷兰成年 2 型糖尿病患者膳食总蛋白、动物蛋白和植物蛋白摄入量与抑郁症状发生率和严重程度之间的横断面关联：霍恩糖尿病护理系统队列。

IF 4.3 2区医学 Q1 MEDICINE, GENERAL & INTERNAL

Preventive medicine

Pub Date : 2024-07-22 DOI: 10.1016/j.ypmed.2024.108065

Maaike M. Migchelbrink , Sanne H.M. Kremers , Nicolette R. den Braver , Lenka Groeneveld , Petra J.M. Elders , Marieke T. Blom , Joline W. Beulens , Femke Rutters

Objective

This study aimed to investigate cross-sectional associations of total, animal, and plant-based protein intake and depressive symptoms in Dutch adults with type 2 diabetes (T2D).

Methods

We included 1137 individuals with T2D (aged 68.6 ± 9.0) from the Hoorn Diabetes Care System cohort. Energy-adjusted protein intake was assessed using a validated Food Frequency Questionnaire. The nine-item Patient Health Questionnaire (PHQ-9) was used to assess the prevalence of depressive symptoms (PHQ-9 ≥ 10 and/or anti-depressant use) and the severity of depressive symptoms (continuous PHQ-9 score). Associations between total, animal, and plant-based protein (quartiles) with depressive symptoms were assessed using multiple logistic and linear regression.

Results

Highest intake of total, animal, and plant-based protein was not associated with the prevalence of depressive symptoms, compared to lowest intake (e.g., total protein, ORQ4vsQ1:0.75, 95%CI 0.42;1.32). For the severity of depressive symptoms, highest total protein intake was significantly associated with lower PHQ-9 scores (ORQ4vsQ1:0.87, 95%CI 0.75;1.00), compared to lowest intake. Animal protein was not associated with the severity of depressive symptoms (β ∼ 1), while the association for plant-based protein was marginally non-significant (βQ4vsQ1:0.88, 95%CI 0.76;1.02).

Conclusion

In individuals with T2D, higher total protein intake was associated with reduced severity of depressive symptoms, but not with the prevalence of depressive symptoms. Further prospective research with a larger sample size is needed to confirm these associations.

研究目的本研究旨在调查荷兰成年 2 型糖尿病（T2D）患者总蛋白质、动物蛋白质和植物蛋白质摄入量与抑郁症状之间的横断面关联：我们纳入了霍恩糖尿病护理系统队列中的 1137 名 2 型糖尿病患者（年龄为 68.6 ± 9.0）。我们使用经过验证的食物频率问卷评估了能量调整后的蛋白质摄入量。九项患者健康问卷（PHQ-9）用于评估抑郁症状的发生率（PHQ-9≥10和/或使用抗抑郁药）和抑郁症状的严重程度（PHQ-9连续得分）。采用多元逻辑回归和线性回归评估了总蛋白、动物蛋白和植物蛋白（四分位数）与抑郁症状之间的关系：结果：与最低摄入量相比，总蛋白、动物蛋白和植物蛋白的最高摄入量与抑郁症状的发生率无关（如总蛋白，ORQ4vsQ1:0.75, 95%CI 0.42;1.32）。就抑郁症状的严重程度而言，与最低摄入量相比，总蛋白质的最高摄入量与较低的 PHQ-9 评分显著相关（ORQ4vsQ1:0.87, 95%CI 0.75;1.00）。动物蛋白与抑郁症状的严重程度无关（β ~ 1），而植物蛋白与抑郁症状的相关性略微不显著（βQ4vsQ1:0.88, 95%CI 0.76;1.02）：在患有 T2D 的人群中，总蛋白质摄入量的增加与抑郁症状严重程度的降低有关，但与抑郁症状的发生率无关。要证实这些关联，还需要进一步开展样本量更大的前瞻性研究。

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引用次数: 0

Birth defects among offspring of California firefighters, 2007–2019 2007-2019 年加利福尼亚消防员后代中的出生缺陷。

IF 4.3 2区医学 Q1 MEDICINE, GENERAL & INTERNAL

Preventive medicine

Pub Date : 2024-07-20 DOI: 10.1016/j.ypmed.2024.108080

Florencia Anunziata , Madison Chapman , Erin Delker , Shana Hayes , Miguel Del Campo , Rebecca J. Baer , Gretchen Bandoli

Purpose

Limited research examines birth defects from maternal or paternal firefighting exposure. This study aims to assess if maternal or paternal occupational exposure to firefighting during periconception is associated with offspring birth defects.

Methods

Data from California birth certificates (2007–2019) were linked to maternal / offspring hospitalization records. Occupation during the periconceptional period was categorized from vital statistics as the following: paternal non-firefighting (n = 4,135,849), paternal firefighting (n = 22,732), maternal non-firefighting (n = 3,332,255) and maternal firefighting (n = 502). Birth defects were identified using ICD codes, grouped by anatomical regions. Adjusted odds ratios were estimated, and sensitivity analyses explored police officer reference groups and detailed birth defect categories.

Results

Offspring of paternal firefighters had lower odds of circulatory defects (aOR = 0.9, 95% CI 0.8, 1.0), oral clefts (aOR = 0.6, 95% CI 0.4, 0.8) and respiratory defects (0.7, 95% CI 0.6, 0.9) compared to paternal non-firefighters. Associations between maternal firefighting and offspring birth defects were imprecise. Substituting police officers as the reference group attenuated findings.

Conclusions

Offspring of paternal firefighters may have similar or slightly lower birth defect odds compared to offspring of non-firefighters. Limited data was available for assessing maternal firefighting outcomes. Future studies should prioritize studies using occupational exposure matrices to limit misclassification of exposure.

目的：有关母亲或父亲接触消防所导致的出生缺陷的研究有限。本研究旨在评估母亲或父亲在围孕期接触消防职业是否与后代出生缺陷有关：方法：将加利福尼亚州出生证明（2007-2019 年）中的数据与母亲/后代的住院记录联系起来。围孕期的职业根据生命统计分类如下：父亲非消防 (n = 4,135,849), 父亲消防 (n = 22,732), 母亲非消防 (n = 3,332,255) 和母亲消防 (n = 502)。出生缺陷使用 ICD 编码进行鉴定，并按解剖区域分组。估算了调整后的几率比，并对警官参照组和详细的出生缺陷类别进行了敏感性分析：结果：与非父方消防员相比，父方消防员的后代出现循环系统缺陷（aOR = 0.9，95% CI 0.8，1.0）、口腔裂隙（aOR = 0.6，95% CI 0.4，0.8）和呼吸系统缺陷（0.7，95% CI 0.6，0.9）的几率较低。母亲从事消防工作与后代出生缺陷之间的关系并不精确。用警察作为参照组会削弱研究结果：与非消防员的后代相比，父亲是消防员的后代出生缺陷几率可能相似或略低。评估母亲消防工作结果的数据有限。未来的研究应优先考虑使用职业暴露矩阵的研究，以限制暴露的错误分类。

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引用次数: 0

Tweeting environmental pollution: Analyzing twitter language to uncover its correlation with county-level obesity rates in the United States 推特环境污染：分析 twitter 语言，揭示其与美国县级肥胖率的相关性。

IF 4.3 2区医学 Q1 MEDICINE, GENERAL & INTERNAL

Preventive medicine

Pub Date : 2024-07-20 DOI: 10.1016/j.ypmed.2024.108081

Jamil M. Lane , Xupin Zhang , Cecilia S. Alcala , Vishal Midya , Kiran Nagdeo , Rui Li , Robert O. Wright

Background

Environmental pollution has been linked to obesogenic tendencies. Using environmental-related posts from Twitter (now known as X) from U.S. counties, we aim to uncover the association between Twitter linguistic data and U.S. county-level obesity rates.

Methods

Analyzing nearly 300 thousand tweets from January 2020 to December 2020 across 207 U.S. counties, using an innovative Differential Language Analysis technique and drawing county-level obesity data from the 2020 Food Environment Atlas to identify distinct linguistic features in Twitter relating to environmental-related posts correlated with socioeconomic status (SES) index indicators, obesity rates, and obesity rates controlled for SES index indicators. We also employed predictive modeling to estimate Twitter language's predictive capacity for obesity rates.

Results

Results revealed a negative correlation between environmental-related tweets and obesity rates, both before and after adjusting for SES. Contrarily, non-environmental-related tweets showed a positive association with higher county-level obesity rates, indicating that individuals living in counties with lower obesity rates tend to tweet environmental-related language more frequently than those living in counties with higher obesity rates. The findings suggest that linguistic patterns and expressions employed in discussing environmental-related themes on Twitter can offer unique insights into the prevailing cross-sectional patterns of obesity rates.

Conclusions

Although Twitter users are a subset of the general population, incorporating environmental-related tweets and county-level obesity rates and using a novel language analysis technique make this study unique. Our results indicated that Twitter users engaging in more active dialog about environmental concerns might exhibit healthier lifestyle practices, contributing to reduced obesity rates.

背景：环境污染与肥胖倾向有关。我们利用美国各县推特（现在称为 X）上与环境相关的帖子，旨在揭示推特语言数据与美国县级肥胖率之间的关联：分析 2020 年 1 月至 2020 年 12 月期间美国 207 个县的近 30 万条推文，使用创新的差异语言分析技术，并从 2020 年食品环境地图集中提取县级肥胖数据，以确定推特中与环境相关帖子相关的独特语言特征，这些语言特征与社会经济地位（SES）指数指标、肥胖率以及控制 SES 指数指标的肥胖率相关。我们还采用了预测模型来估计推特语言对肥胖率的预测能力：结果显示，在调整社会经济地位指数之前和之后，环境相关推文与肥胖率之间均呈负相关。相反，与环境无关的推文与较高的县级肥胖率呈正相关，这表明生活在肥胖率较低的县的人往往比生活在肥胖率较高的县的人更频繁地在推特上发布与环境有关的语言。研究结果表明，在推特上讨论与环境相关的主题时所使用的语言模式和表达方式可以为了解肥胖率的普遍横截面模式提供独特的见解：尽管推特用户是普通人群的一个子集，但将与环境相关的推文和县级肥胖率纳入其中，并使用新颖的语言分析技术，使本研究独具特色。我们的研究结果表明，参与有关环境问题的更积极对话的推特用户可能会表现出更健康的生活方式，从而有助于降低肥胖率。

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引用次数: 0

Clustering of behavioral economic biases in decision-making and risk for cigarette smoking and other substance use in women and men 决策中的行为经济学偏差与女性和男性吸烟及其他药物使用风险的聚类。

IF 4.3 2区医学 Q1 MEDICINE, GENERAL & INTERNAL

Preventive medicine

Pub Date : 2024-07-19 DOI: 10.1016/j.ypmed.2024.108072

Eric A. Thrailkill , Michael DeSarno , Stephen T. Higgins

Background

Low loss aversion (LA) and high delay discounting (DD) are behavioral-economic decision-making biases that independently predict cigarette smoking and other risky substance use. Here we examine (1) whether low-LA and high-DD co-occur, (2) does co-occurrence increase the odds of current smoking and other substance use compared to only low-LA, high-DD, or neither; and (3) potential gender differences in these associations.

Method

Data are from five studies with U.S. adults who currently smoked or never-smoked cigarettes recruited using online convenience sampling matching on gender and education. Participants completed identical sociodemographic, substance use (cigarette, other drugs, alcohol), and LA (hypothetical 50–50 gambles) and DD (monetary-choice questionnaire) measures. LA and DD scores were dichotomized as low and high using Receiver-Operating-Characteristic Curve logistic regression.

Results

LA and DD each independently predicted substance use and with few exceptions were not influenced by gender. Low-LA compared to high-LA predicted two-fold greater odds of co-occurring high-DD (AOR = 2.120, 95%CI:1.749–2.571, p < .0001). Similarly, high-DD compared to low DD predicted two-fold greater odds of low-LA (AOR = 2.118, 95%CI:1.747–2.568, p < .0001). Among those with co-occurring low-LA and high-DD, odds of substance use were 5–10 times greater than those exhibiting neither, and 2–3 times greater than those exhibiting only low-LA or high-DD.

Conclusions

Low-LA and high-DD cluster in women and men such that exhibiting one of these decision-making biases doubles the odds of exhibiting the other. These results demonstrate reliable clustering of low-LA and high-DD and a striking increase in risk for substance use relative to having only one or neither decision-making bias.

背景：低损失厌恶（LA）和高延迟贴现（DD）是行为经济决策偏差，可独立预测吸烟和其他危险物质的使用。在此，我们研究了（1）低LA和高DD是否同时存在；（2）与仅低LA、高DD或两者均不存在相比，同时存在是否会增加当前吸烟和使用其他药物的几率；以及（3）这些关联中潜在的性别差异：数据来自五项研究，研究对象为美国成年人，他们目前吸烟或从未吸烟，研究采用在线便利抽样的方式，根据性别和教育程度进行匹配。参与者完成了相同的社会人口学、药物使用（香烟、其他药物、酒精）、LA（假设五五分成赌博）和 DD（货币选择问卷）测量。使用接收器-操作-特征曲线逻辑回归法将LA和DD得分分为低分和高分：结果：LA 和 DD 均可独立预测药物使用情况，除少数例外情况外，不受性别影响。低 LA 与高 LA 相比，并发高 DD 的几率要高出两倍（AOR = 2.120，95%CI:1.749-2.571, p 结论：低 LA 和高 DD 聚类在一起：低LA和高DD在女性和男性中聚集，表现出其中一种决策偏差会使表现出另一种决策偏差的几率增加一倍。这些结果表明，低LA和高DD具有可靠的聚集性，相对于只有一种或两种决策偏差，使用药物的风险显著增加。

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引用次数: 0

Association between Bacillus Calmette-Guérin (BCG) vaccination and inflammatory bowel disease: A two-stage sampling design within the Quebec Birth Cohort on Immunity and Health (CO·MMUNITY) 卡介苗（BCG）接种与炎症性肠病之间的关系：魁北克免疫与健康出生队列（CO-MMUNITY）中的两阶段抽样设计。

IF 4.3 2区医学 Q1 MEDICINE, GENERAL & INTERNAL

Preventive medicine

Pub Date : 2024-07-17 DOI: 10.1016/j.ypmed.2024.108071

Canisius Fantodji , Prévost Jantchou , Andrea Benedetti , Marie-Claude Rousseau

Background

Bacillus Calmette-Guérin (BCG) vaccination, primarily administered to prevent tuberculosis, exhibits nonspecific immune effects and could play a role in inflammatory bowel disease prevention. We investigated the associations of BCG with Crohn's disease and ulcerative colitis, and assessed sex-differences.

Methods

This two-stage study included 365,206 Canadians from the Quebec Birth Cohort on Immunity and Health (1970–2014; stage 1). Vaccination status was registry-based and inflammatory bowel disease cases were identified from health services with validated algorithms. We documented additional factors among 2644 participants in a nested case-control study in 2021 (stage 2). A two-stage logistic regression analysis was applied to estimate the odds ratios (OR), corrected for sampling fractions and adjusted for confounding factors. We used interaction terms to assess sex-differences on the multiplicative scale.

Results

In the stage 1 sample, 2419 cases of Crohn's disease and 1079 of ulcerative colitis were included. Forty-six percent of non-cases received the BCG vaccine as compared to 47% for Crohn's disease and 49% for ulcerative colitis. Associations differed by sex. BCG vaccination was not associated with Crohn's disease among men (OR = 0.91; 95% CI: 0.79–1.04) but was related to an increased risk among women (OR = 1.13; 95% CI: 1.00–1.28, P interaction: 0.001). For ulcerative colitis, there was a tendency toward a slightly elevated risk among men (OR = 1.09; 95%CI: 0.90–1.32), whereas the risk was more substantial for women (OR = 1.17; 95% CI:0.99–1.39, P interaction: <0.001).

Conclusion

BCG vaccination does not play a preventive role in inflammatory bowel disease. Our results point to distinct associations between men and women.

背景：卡介苗（Bacillus Calmette-Guérin，BCG）主要用于预防结核病，具有非特异性免疫效应，可在预防炎症性肠病方面发挥作用。我们调查了卡介苗与克罗恩病和溃疡性结肠炎的关系，并评估了性别差异：这项研究分为两个阶段，包括魁北克免疫与健康出生队列（1970-2014 年；第一阶段）中的 365 206 名加拿大人。疫苗接种情况以登记册为基础，炎症性肠病病例则通过验证算法从医疗服务机构中确定。我们在 2021 年的一项嵌套病例对照研究中记录了 2644 名参与者的其他因素（第二阶段）。我们采用了两阶段逻辑回归分析来估算几率比（OR），并对抽样分数进行了校正，同时对混杂因素进行了调整。我们使用交互项来评估乘法表中的性别差异：在第一阶段样本中，共纳入了 2419 例克罗恩病病例和 1079 例溃疡性结肠炎病例。46%的非病例接种了卡介苗，而克罗恩病为47%，溃疡性结肠炎为49%。两者之间的关系因性别而异。卡介苗接种与男性克罗恩病无关（OR = 0.91；95% CI：0.79-1.04），但与女性风险增加有关（OR = 1.13；95% CI：1.00-1.28，P交互作用：0.001）。就溃疡性结肠炎而言，男性的风险有轻微升高的趋势（OR = 1.09；95%CI：0.90-1.32），而女性的风险更高（OR = 1.17；95%CI：0.99-1.39，P 交互作用：结论卡介苗对炎症性肠病没有预防作用。我们的研究结果表明，男性和女性之间存在不同的关联。

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引用次数: 0

Are the physical activity habits of healthcare professionals associated with their physical activity promotion and counselling?: A systematic review 医护人员的体育锻炼习惯是否与他们的体育锻炼推广和咨询有关？系统综述。

IF 4.3 2区医学 Q1 MEDICINE, GENERAL & INTERNAL

Preventive medicine

Pub Date : 2024-07-17 DOI: 10.1016/j.ypmed.2024.108069

Margarida D. Borges , Tiago D. Ribeiro , Miguel Peralta , Bruna R. Gouveia , Adilson Marques

Objective

Healthcare professionals (HCPs) play an important role in conducting brief physical activity counselling during consultations, representing one of the population's most cost-effective interventions for its promotion. Despite this, their clinical practice often falls short in addressing physical activity with the necessary depth and frequency. This study aimed to synthesise the literature concerning the association between the physical activity habits of HCPs and their attitudes toward physical activity promotion and counselling.

Methods

The systematic review followed PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. Its protocol was registered in PROSPERO under ID: CRD42023408302. In March 2023, a comprehensive search was conducted using key terms related to physical activity levels and HCPs counselling practices across the Web of Science, Scopus, PubMed, SPORTDiscus, APA PsycInfo, and CINAHL databases. Registered HCPs classified under the International Standard Classification of Occupations (ISCO) were included. The Newcastle-Ottawa Scale was used for assessing articles quality.

Results

The search yielded 6618 articles, with 51 meeting the inclusion criteria after filtering and cross-referencing. Predominantly cross-sectional studies were included, mainly involving HCPs responding to questionnaires regarding their physical activity habits and promotion and counselling practices. Heterogeneous results were found.

Conclusion

High-quality studies mainly concluded that higher physical activity levels among HCPs were associated with more physical activity promotion and counselling practices. These findings are an important contribution to the relevance of the physical activity practice by HCPs and highlighting the importance of promoting its counselling in clinical practice.

目的：医疗保健专业人员（HCPs）在就诊过程中提供简短的体育锻炼咨询方面发挥着重要作用，是促进全民体育锻炼的最具成本效益的干预措施之一。尽管如此，他们在临床实践中往往不能以必要的深度和频率开展体育锻炼。本研究旨在综述有关保健医生的体育锻炼习惯与他们对体育锻炼推广和咨询的态度之间关系的文献：系统性综述遵循 PRISMA（系统性综述和元分析首选报告项目）指南。其方案已在 PROSPERO 注册，ID：CRD42023408302。2023 年 3 月，我们在 Web of Science、Scopus、PubMed、SPORTDiscus、APA PsycInfo 和 CINAHL 数据库中使用与体育锻炼水平和保健医生咨询实践相关的关键术语进行了全面检索。根据国际标准职业分类（ISCO）分类的注册保健医生也包括在内。文章质量采用纽卡斯尔-渥太华量表进行评估：检索结果显示，共有 6618 篇文章，经过筛选和交叉引用后，有 51 篇符合纳入标准。纳入的文章以横断面研究为主，主要涉及卫生保健人员对其体育锻炼习惯以及推广和咨询做法的问卷调查。研究结果不尽相同：高质量研究的主要结论是，高级保健人员较高的体育锻炼水平与较多的体育锻炼推广和咨询活动有关。这些研究结果是对医疗保健人员体育锻炼实践相关性的重要贡献，并强调了在临床实践中推广体育锻炼咨询的重要性。

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引用次数: 0

Associations of steps per day and step intensity with the risk of cancer: Findings from the Women's Health Accelerometry Collaboration cohort 每天步数和步数强度与癌症风险的关系：妇女健康加速度测量合作队列的研究结果。

IF 4.3 2区医学 Q1 MEDICINE, GENERAL & INTERNAL

Preventive medicine

Pub Date : 2024-07-17 DOI: 10.1016/j.ypmed.2024.108070

Carmen C. Cuthbertson , Kelly R. Evenson , Fang Wen , Christopher C. Moore , Annie G. Howard , Chongzhi Di , Humberto Parada Jr , Charles E. Matthews , JoAnn E. Manson , Julie Buring , Eric J. Shiroma , Andrea Z. LaCroix , I-Min Lee

Objective

Accumulating more steps/day is associated with a lower risk of cancer mortality and composite cancer outcomes. However, less is known about the relationship of steps/day with the risk of multiple site-specific cancers.

Methods

This study included >22,000 women from the Women's Health Accelerometry Collaboration Cohort (2011−2022), comprised of women from the Women's Health Study and Women's Health Initiative Objective Physical Activity and Cardiovascular Health Study. Steps/day and step intensity were collected with accelerometry. Incident cancer cases and deaths were adjudicated. Stratified Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) of the associations of steps/day and step intensity with incident breast, colon, endometrial, lung, and ovarian cancers, a composite of 13 physical activity-related cancers, total invasive cancer, and fatal cancer.

Results

On average, women were 73.4 years old, accumulated 4993 steps/day, and had 7.9 years of follow-up. There were small nonsignificant inverse associations with the risks of colon cancer (HR = 0.94, 95% CI: 0.83, 1.05), endometrial cancer (HR = 0.91, 95% CI: 0.82, 1.01), and fatal cancer (HR = 0.95 95% CI: 0.90, 1.00) per 1000 steps/day. More minutes at ≥40 steps/min and a faster peak 10- and 30-min step cadence were associated with a lower risk of endometrial cancer, but findings were attenuated after adjustment for body mass index and steps/day.

Conclusions

Among women 62–97 years, there were small nonsignificant inverse associations of colon, endometrial, and fatal cancer with more steps/day. Epidemiologic studies with longer follow-up and updated assessments are needed to further explore these associations.

目的：每天积累更多的步数与较低的癌症死亡风险和癌症综合结果有关。然而，人们对步数/天与多种特定部位癌症风险之间的关系知之甚少：这项研究纳入了来自妇女健康加速度测量合作队列（2011-2022 年）的超过 22,000 名妇女，该队列由妇女健康研究和妇女健康倡议目标体力活动和心血管健康研究的妇女组成。通过加速度计收集每天的步数和步数强度。对癌症病例和死亡病例进行判定。采用分层 Cox 比例危险模型来估算步数/天和步数强度与乳腺癌、结肠癌、子宫内膜癌、肺癌和卵巢癌、13 种与体力活动有关的癌症的复合病例、总浸润性癌症和致命癌症的危险比（HRs）和 95% 置信区间（CIs）：妇女平均年龄为 73.4 岁，每天累积步数为 4993 步，随访时间为 7.9 年。每 1000 步/天与结肠癌（HR = 0.94，95% CI：0.83，1.05）、子宫内膜癌（HR = 0.91，95% CI：0.82，1.01）和致命癌症（HR = 0.95，95% CI：0.90，1.00）的发病风险呈微小的非显著负相关。步速≥40步/分钟的时间越长、10分钟和30分钟步速峰值越快，患子宫内膜癌的风险就越低，但在对体重指数和每天步数进行调整后，研究结果有所减弱：结论：在 62-97 岁的女性中，结肠癌、子宫内膜癌和致命癌症与每天步数较多呈微小的非显著性反向关系。需要进行更长时间的随访和更新评估的流行病学研究，以进一步探讨这些关联。

{"title":"Associations of steps per day and step intensity with the risk of cancer: Findings from the Women's Health Accelerometry Collaboration cohort","authors":"Carmen C. Cuthbertson , Kelly R. Evenson , Fang Wen , Christopher C. Moore , Annie G. Howard , Chongzhi Di , Humberto Parada Jr , Charles E. Matthews , JoAnn E. Manson , Julie Buring , Eric J. Shiroma , Andrea Z. LaCroix , I-Min Lee","doi":"10.1016/j.ypmed.2024.108070","DOIUrl":"10.1016/j.ypmed.2024.108070","url":null,"abstract":"<div><h3>Objective</h3><p>Accumulating more steps/day is associated with a lower risk of cancer mortality and composite cancer outcomes. However, less is known about the relationship of steps/day with the risk of multiple site-specific cancers.</p></div><div><h3>Methods</h3><p>This study included >22,000 women from the Women's Health Accelerometry Collaboration Cohort (2011−2022), comprised of women from the Women's Health Study and Women's Health Initiative Objective Physical Activity and Cardiovascular Health Study. Steps/day and step intensity were collected with accelerometry. Incident cancer cases and deaths were adjudicated. Stratified Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) of the associations of steps/day and step intensity with incident breast, colon, endometrial, lung, and ovarian cancers, a composite of 13 physical activity-related cancers, total invasive cancer, and fatal cancer.</p></div><div><h3>Results</h3><p>On average, women were 73.4 years old, accumulated 4993 steps/day, and had 7.9 years of follow-up. There were small nonsignificant inverse associations with the risks of colon cancer (HR = 0.94, 95% CI: 0.83, 1.05), endometrial cancer (HR = 0.91, 95% CI: 0.82, 1.01), and fatal cancer (HR = 0.95 95% CI: 0.90, 1.00) per 1000 steps/day. More minutes at ≥40 steps/min and a faster peak 10- and 30-min step cadence were associated with a lower risk of endometrial cancer, but findings were attenuated after adjustment for body mass index and steps/day.</p></div><div><h3>Conclusions</h3><p>Among women 62–97 years, there were small nonsignificant inverse associations of colon, endometrial, and fatal cancer with more steps/day. Epidemiologic studies with longer follow-up and updated assessments are needed to further explore these associations.</p></div>","PeriodicalId":20339,"journal":{"name":"Preventive medicine","volume":"186 ","pages":"Article 108070"},"PeriodicalIF":4.3,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141727680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The impact of residential environment on stroke onset and its spatial heterogeneity: A multiscale exploration in Shanghai 居住环境对中风发病的影响及其空间异质性：上海的多尺度研究

IF 4.3 2区医学 Q1 MEDICINE, GENERAL & INTERNAL

Preventive medicine

Pub Date : 2024-07-14 DOI: 10.1016/j.ypmed.2024.108067

Jiaqi Li , Yishao Shi , Shanzhu Li , Hui Xu , Tianhui Tao , Qianxu Wang , Katabarwa Murenzi Gilbert

Background

Stroke is a worldwide concern due to its high disability and mortality rates, especially in many countries entering ageing societies. This study aims to understand the spatial heterogeneity of stroke onset and residential environment influence scopes from multiscale.

Methods

The 2013 to 2022 spatiotemporal distribution pattern of stroke onset was obtained via out-patient data from a hospital in Shanghai. Then nine residential environmental factors were selected to estimate the association of stroke onset by multiscale geographically weighted regression (MGWR), in three scenarios.

Results

Accessibility to pubs/bars (PUB) and building density (BD) were the top two residential environmental factors both for the entire sample and by gender. Stress-related environmental factors have a greater impact on the onset of stroke in men but are limited in scope. The population of elderly people have relevance to environmental variables heterogeneity. The indicators relating to unhealthy food and alcohol suggest that habit-inducing environmental factors have a limited impact on stroke onset, but rather that pre-existing habits play a greater role.

Conclusions

MGWR analyses individual components across multiple bandwidths, revealing geographical disparities in the impact of elements that would otherwise be undetected on a global scale. Environmental factors have a limited impact on the onset of stroke. When society is faced with both heavy ageing and fiscal constraints, some of the blue-green space budgets can be scaled back to invest in more secure facilities.

背景：中风因其高致残率和高死亡率而受到全世界的关注，尤其是在许多进入老龄化社会的国家。本研究旨在从多尺度了解中风发病的空间异质性和居住环境的影响范围：方法：通过上海某医院的门诊数据，获得 2013 年至 2022 年脑卒中发病的时空分布模式。方法：通过上海某医院的门诊数据获取 2013 年至 2022 年脑卒中发病的时空分布模式，然后选取 9 个居住环境因素，在三种情景下通过多尺度地理加权回归（MGWR）估计脑卒中发病的相关性：结果：无论从整个样本还是从性别来看，酒吧（PUB）和建筑密度（BD）都是排名前两位的居住环境因素。与压力相关的环境因素对男性中风发病的影响更大，但范围有限。老年人群与环境变量的异质性有关。与不健康食品和酒精有关的指标表明，习惯性环境因素对中风发病的影响有限，而原有习惯的作用更大：MGWR分析了多个带宽下的单个成分，揭示了各种因素影响的地域差异，而这些因素在全球范围内是无法发现的。环境因素对中风发病的影响有限。在社会面临严重老龄化和财政紧缩的情况下，可以缩减部分蓝绿空间预算，投资于更安全的设施。

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引用次数: 0

IF 4.3 2区医学 Q1 MEDICINE, GENERAL & INTERNAL

Preventive medicine

Pub Date : 2024-07-14 DOI: 10.1016/j.ypmed.2024.108068

Jessica Liu, Bonnie Halpern-Felsher

Objective

This study identifies brands of nicotine pouches used in 2021, just before the surge in popularity of Zyn use.

Methods

We conducted a national, cross-sectional online survey of a general U.S. population (November to December 2021; N = 6131; age 13–40) via Qualtrics panels. Descriptive analyses and chi-squared tests (alpha = 0.05) were performed to assess ever and past-30-day use of nicotine pouch brands across adolescents (13−20), young adults (21–24), and adults (25–40), and to assess frequency of popular brands used among peers.

Results

The top brands ever used were Zyn (overall: 30.9%; adolescents: 31.9%; young adults: 33.2%; adults: 28.3%) and Lyft (overall: 28.8%; adolescents: 28.4%; young adults: 32.9%; adults: 26.3%), with no differences in ever-use by age group (p's > 0.095). The top brands used in the past-30-days were Zyn (overall: 26.4%; adolescents: 24.5%; young adults: 24.3%; adults: 30.0%) and Rush (overall: 24.2%; adolescents: 21.0%; young adults: 22.7%; adults: 28.6%). Adults (vs. adolescents, young adults) were more likely to report past-30-day use of Lyft (p = 0.004). Participants indicated Zyn (18.5%) and Lyft (18.2%) to be the most popular brands among peers.

Conclusions

Even in 2021, Zyn was the most popular brand of nicotine pouches. Findings will help regulate and reduce impact of marketing of Zyn.

研究目的本研究确定了 2021 年使用的尼古丁袋品牌，当时正值 Zyn 的使用激增之前：我们通过 Qualtrics 面板对美国普通人群进行了一次全国性横断面在线调查（2021 年 11 月至 12 月；N = 6131；年龄 13-40 岁）。调查进行了描述性分析和卡方检验（α=0.05），以评估青少年（13-20 岁）、年轻成年人（21-24 岁）和成年人（25-40 岁）曾经和过去 30 天内使用尼古丁袋品牌的情况，并评估同龄人使用流行品牌的频率：曾经使用最多的品牌是 Zyn（总体：30.9%；青少年：31.9%；青壮年：33.2%；成年人：28.3%）和 Lyft（总体：28.8%；青少年：28.4%；青壮年：32.9%；成年人：26.3%），不同年龄组的曾经使用情况没有差异（P>0.095）。过去 30 天内使用最多的品牌是 Zyn（总体：26.4%；青少年：24.5%；青壮年：24.3%；成人：30.0%）和 Rush（总体：24.2%；青少年：21.0%；青壮年：22.7%；成人：28.6%）。成年人（与青少年和年轻成年人相比）更有可能报告过去 30 天内使用过 Lyft（p = 0.004）。参与者表示 Zyn（18.5%）和 Lyft（18.2%）是同龄人中最受欢迎的品牌：即使在 2021 年，Zyn 也是最受欢迎的尼古丁袋品牌。研究结果将有助于规范和减少 Zyn 的营销影响。

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引用次数: 0