Pub Date : 2019-01-01DOI: 10.2991/isils-19.2019.76
I. Spichak, Tatyana Babanina, I. Zhirova
The article presents the results of improving the drug supply for women with menopausal disorders at the regional level. A sociological study of women with climacteric disorders as a consumer of pharmaceutical care has been conducted. Marketing analysis of the Russian and regional pharmaceutical markets for the prevention and treatment of menopausal disorders has been carried out; assessment of competitiveness of hormonal, homeopathic drugs and nutritional supplements for the prevention and treatment of menopausal disorders in women; proposals have been developed for pharmacies to formulate an assortment policy in the field of drug procurement for the prevention and treatment of menopausal disorders in women. Keywords—pharmaceutical market, climacteric disorders, menopause, medicines, sociological research, consumer preferences, compliance with therapy, marketing research, drug competitiveness
{"title":"Improvement of Drug Supply for Women with Climacteric Disorders","authors":"I. Spichak, Tatyana Babanina, I. Zhirova","doi":"10.2991/isils-19.2019.76","DOIUrl":"https://doi.org/10.2991/isils-19.2019.76","url":null,"abstract":"The article presents the results of improving the drug supply for women with menopausal disorders at the regional level. A sociological study of women with climacteric disorders as a consumer of pharmaceutical care has been conducted. Marketing analysis of the Russian and regional pharmaceutical markets for the prevention and treatment of menopausal disorders has been carried out; assessment of competitiveness of hormonal, homeopathic drugs and nutritional supplements for the prevention and treatment of menopausal disorders in women; proposals have been developed for pharmacies to formulate an assortment policy in the field of drug procurement for the prevention and treatment of menopausal disorders in women. Keywords—pharmaceutical market, climacteric disorders, menopause, medicines, sociological research, consumer preferences, compliance with therapy, marketing research, drug competitiveness","PeriodicalId":20489,"journal":{"name":"Proceedings of the 1st International Symposium Innovations in Life Sciences (ISILS 2019)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82925864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.2991/isils-19.2019.37
D. Kompantsev, A. Chakhirova, T. Gutnova
— Therapeutic sulphide silt mud from Tambukan lake has been formed for a long period of time. Balneological value of silt mud from that specific lake is high because of high level of ferrous sulphides and water-soluble salts in it’s content, including recognized as therapeutically active bromine and boric acid; high concentration of lipids and carotenoids, which have anti-inflammatory, anti-bacteria, immune stimulating and bio stimulating effects. Goal: development of the method for stimulation of the peloid extract obtaining process from the Tambukan mud by an ultrasound-assisted extraction with further determination of biologically active substance using a spectrophotometric method. The research is based on formerly known and patented methods, offered by Kh.G.Karagulov. The method is reasonable, allows to extract carotenoid in full. The disadvantage of it is the energy-demanding and the usage of an organic solvent. As the object of the research a deep seated mud sample from the Tambukan lake was taken. After an ultrasound-assisted extraction there was obtained an oily extract from the mud sample. Quantitative content estimation was held out using a spectrophotometric method in visible region of absorption. The ability to optimize the process of peloid extraction from the Tambukan mud by the ultrasound-assisted extraction has been proven. Offered method for extraction and determination of carotenoid amount in Tambukan mud is less resource- and energy-demanding. Alongside with that it provides best possible carotenoid amount in the outcome. Effective and less expensive method to obtain peloid from Tambukan mud has been developed. The research results point out that the level of carotenoids in Tambukan silt mud has been reduced resulting in serious reduction of therapeutic effect. in
{"title":"Optimization of a Method for Obtaining and Determination of Carotenoids in Tambukan Mud","authors":"D. Kompantsev, A. Chakhirova, T. Gutnova","doi":"10.2991/isils-19.2019.37","DOIUrl":"https://doi.org/10.2991/isils-19.2019.37","url":null,"abstract":"— Therapeutic sulphide silt mud from Tambukan lake has been formed for a long period of time. Balneological value of silt mud from that specific lake is high because of high level of ferrous sulphides and water-soluble salts in it’s content, including recognized as therapeutically active bromine and boric acid; high concentration of lipids and carotenoids, which have anti-inflammatory, anti-bacteria, immune stimulating and bio stimulating effects. Goal: development of the method for stimulation of the peloid extract obtaining process from the Tambukan mud by an ultrasound-assisted extraction with further determination of biologically active substance using a spectrophotometric method. The research is based on formerly known and patented methods, offered by Kh.G.Karagulov. The method is reasonable, allows to extract carotenoid in full. The disadvantage of it is the energy-demanding and the usage of an organic solvent. As the object of the research a deep seated mud sample from the Tambukan lake was taken. After an ultrasound-assisted extraction there was obtained an oily extract from the mud sample. Quantitative content estimation was held out using a spectrophotometric method in visible region of absorption. The ability to optimize the process of peloid extraction from the Tambukan mud by the ultrasound-assisted extraction has been proven. Offered method for extraction and determination of carotenoid amount in Tambukan mud is less resource- and energy-demanding. Alongside with that it provides best possible carotenoid amount in the outcome. Effective and less expensive method to obtain peloid from Tambukan mud has been developed. The research results point out that the level of carotenoids in Tambukan silt mud has been reduced resulting in serious reduction of therapeutic effect. in","PeriodicalId":20489,"journal":{"name":"Proceedings of the 1st International Symposium Innovations in Life Sciences (ISILS 2019)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78553107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.2991/isils-19.2019.20
Y. Dereglazova, I. Spichak, E. Kaliuzhnaya
The article presents the developed methodological approach to the technology of conducting a multi-aspect examination of the range of pharmaceutical products. This approach may be of interest for optimizing the prescription of pharmaceutical products by doctors in medical organizations during the pharmacotherapy of patients with various nosologies in the conditions of outpatient and inpatient treatment Keywords—pharmaceutical assistance, pharmaceutical products, comprehensive pharmacoeconomic research, multidimensional assortment expertise
{"title":"Methodical Approach to Carrying out a Multi-Aspect Examination of Pharmaceutical Products","authors":"Y. Dereglazova, I. Spichak, E. Kaliuzhnaya","doi":"10.2991/isils-19.2019.20","DOIUrl":"https://doi.org/10.2991/isils-19.2019.20","url":null,"abstract":"The article presents the developed methodological approach to the technology of conducting a multi-aspect examination of the range of pharmaceutical products. This approach may be of interest for optimizing the prescription of pharmaceutical products by doctors in medical organizations during the pharmacotherapy of patients with various nosologies in the conditions of outpatient and inpatient treatment Keywords—pharmaceutical assistance, pharmaceutical products, comprehensive pharmacoeconomic research, multidimensional assortment expertise","PeriodicalId":20489,"journal":{"name":"Proceedings of the 1st International Symposium Innovations in Life Sciences (ISILS 2019)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74453104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.2991/isils-19.2019.41
N. Kotsareva, O. Shabetya, A. Kryukov
—The results of selection work for restoring the varietal qualities of Strigunovsky local varieties of bulb onion. 7 promising lines of onions with stable varietal qualities, such as the shape and color of the bulbs, the yield of bulbs and seed productivity were obtained.
{"title":"Variability Parameters of Strigunovsky Local Variety of Bulb Onion","authors":"N. Kotsareva, O. Shabetya, A. Kryukov","doi":"10.2991/isils-19.2019.41","DOIUrl":"https://doi.org/10.2991/isils-19.2019.41","url":null,"abstract":"—The results of selection work for restoring the varietal qualities of Strigunovsky local varieties of bulb onion. 7 promising lines of onions with stable varietal qualities, such as the shape and color of the bulbs, the yield of bulbs and seed productivity were obtained.","PeriodicalId":20489,"journal":{"name":"Proceedings of the 1st International Symposium Innovations in Life Sciences (ISILS 2019)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81258060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.2991/isils-19.2019.61
E. Pozhidaeva, E. Popov, Yana Dymovskih
—Currently, there is an increasing interest in exopolysaccharides as effective biocorrector and auxiliary technological agents. Experimental studies were carried out to obtain fermented milk ice cream with a high content of exopolysaccharides. As a nutrient substrate for the cultivation of probiotic microorganisms, a mixture was used to obtain ice cream, including dairy and non-dairy components. The starter cultures included certain strains of microorganisms: Streptococcus thermophilus, Lactobacillus delbrueckii ssp. bulgaricus. It was experimentally established that ice-cream with the addition of a bacterial starter culture YO-PROX 777, including thermophilic lactic acid strains of the microorganisms Streptococcus thermophiles, Lactobacillus delbrueckii ssp, has the greatest ssp. bulgaricus. It was established that the highest concentration of exopolysaccharides is contained in ice cream using the starter culture «YO-PROX 777».
{"title":"Exopolysaccharide Fermented Milk Ice Cream","authors":"E. Pozhidaeva, E. Popov, Yana Dymovskih","doi":"10.2991/isils-19.2019.61","DOIUrl":"https://doi.org/10.2991/isils-19.2019.61","url":null,"abstract":"—Currently, there is an increasing interest in exopolysaccharides as effective biocorrector and auxiliary technological agents. Experimental studies were carried out to obtain fermented milk ice cream with a high content of exopolysaccharides. As a nutrient substrate for the cultivation of probiotic microorganisms, a mixture was used to obtain ice cream, including dairy and non-dairy components. The starter cultures included certain strains of microorganisms: Streptococcus thermophilus, Lactobacillus delbrueckii ssp. bulgaricus. It was experimentally established that ice-cream with the addition of a bacterial starter culture YO-PROX 777, including thermophilic lactic acid strains of the microorganisms Streptococcus thermophiles, Lactobacillus delbrueckii ssp, has the greatest ssp. bulgaricus. It was established that the highest concentration of exopolysaccharides is contained in ice cream using the starter culture «YO-PROX 777».","PeriodicalId":20489,"journal":{"name":"Proceedings of the 1st International Symposium Innovations in Life Sciences (ISILS 2019)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80086484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.2991/isils-19.2019.73
E. Solomonova, N. Trusov, T. Nozdrina
The purpose of study is to identify possibilities of using fruits of eleutherococcuses Eleutherococcus senticosus Rupr. & Maxim. аnd Eleutherococcus sessiliflorus Rupr. & Maxim., which are undergoing introduction tests in arboretum of N.V. Tsytsin Main Botanical Garden of Russian Academy of Science, as easily renewable biosafety drug and food resource. By standard methods, comparative morphology-anatomical and morphometric study of fruits was carried out; content of air-dry, absolutely-dry substance and ascorbic acid was determined in them; statistical processing of the results was performed. The fleshy drupes that we studied vary in fruits shape, by number, shape and size of stones. Features and similarities of anatomical structure of exocarp, mesocarp and endocarp of fruits, typical for most members of the Araliaceae family, were revealed. Fresh fruits of E. senticosus are smaller and lighter than fruits of E. sessiliflorus, but surpass them in terms of volume of stones and amount of ascorbic acid; content of absolutely-dry matter in them is equally high. We propose to consider fruits of both types as a new promising raw material for the production of biologically active additives and functional foods, alternative to traditional raw materials from roots of eleutherococcuses, traumatic to the plants. Keywords—eleutherococcus, morphology-anatomical structure, morphometric parameters, air-dry mass, absolutelydry matter, vitamin C
{"title":"Opportunities for Using of Eleutherococcuses Fruits as a New Food Raw Material","authors":"E. Solomonova, N. Trusov, T. Nozdrina","doi":"10.2991/isils-19.2019.73","DOIUrl":"https://doi.org/10.2991/isils-19.2019.73","url":null,"abstract":"The purpose of study is to identify possibilities of using fruits of eleutherococcuses Eleutherococcus senticosus Rupr. & Maxim. аnd Eleutherococcus sessiliflorus Rupr. & Maxim., which are undergoing introduction tests in arboretum of N.V. Tsytsin Main Botanical Garden of Russian Academy of Science, as easily renewable biosafety drug and food resource. By standard methods, comparative morphology-anatomical and morphometric study of fruits was carried out; content of air-dry, absolutely-dry substance and ascorbic acid was determined in them; statistical processing of the results was performed. The fleshy drupes that we studied vary in fruits shape, by number, shape and size of stones. Features and similarities of anatomical structure of exocarp, mesocarp and endocarp of fruits, typical for most members of the Araliaceae family, were revealed. Fresh fruits of E. senticosus are smaller and lighter than fruits of E. sessiliflorus, but surpass them in terms of volume of stones and amount of ascorbic acid; content of absolutely-dry matter in them is equally high. We propose to consider fruits of both types as a new promising raw material for the production of biologically active additives and functional foods, alternative to traditional raw materials from roots of eleutherococcuses, traumatic to the plants. Keywords—eleutherococcus, morphology-anatomical structure, morphometric parameters, air-dry mass, absolutelydry matter, vitamin C","PeriodicalId":20489,"journal":{"name":"Proceedings of the 1st International Symposium Innovations in Life Sciences (ISILS 2019)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79453764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.2991/isils-19.2019.44
A. Krolevets, N. Myachikova, K. Semichev
— The research paper includes the information on the application of nanostructured motherwort extract in the production of fruit jelly candy, which can be used as a therapeutic functional food product. The size of nanostructured motherwort extract was determined by a nanoparticle tracking analysis (NTA). It depended on a shell nature significantly.
{"title":"Properties of Nanostuctured Motherwort Extract and Its Application in Fruit Jelly Candy Production","authors":"A. Krolevets, N. Myachikova, K. Semichev","doi":"10.2991/isils-19.2019.44","DOIUrl":"https://doi.org/10.2991/isils-19.2019.44","url":null,"abstract":"— The research paper includes the information on the application of nanostructured motherwort extract in the production of fruit jelly candy, which can be used as a therapeutic functional food product. The size of nanostructured motherwort extract was determined by a nanoparticle tracking analysis (NTA). It depended on a shell nature significantly.","PeriodicalId":20489,"journal":{"name":"Proceedings of the 1st International Symposium Innovations in Life Sciences (ISILS 2019)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74452427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.2991/isils-19.2019.35
V. Klyueva, A. Sirotin, Elisaveta Rypalenko, Khristina Ozarko, Khristina Degtyareva
—The analysis of the inhibiting effect of antibiotic from the cephalosporin series, nanoencapsulated gellan and xanthan gum in comparison with native antibiotics was performed. Differences in the effect of drugs depending on concentration were studied as well as positive effect of prolongation of activity nanoencapsulated form in low concentration. The expediency of using gellan and xanthan gum nanoencapsulation of cephalosporin antibiotic was shown.
{"title":"Antimicrobial Activity of Native and Nanoencapsulated Cephalosporin Antibiotics","authors":"V. Klyueva, A. Sirotin, Elisaveta Rypalenko, Khristina Ozarko, Khristina Degtyareva","doi":"10.2991/isils-19.2019.35","DOIUrl":"https://doi.org/10.2991/isils-19.2019.35","url":null,"abstract":"—The analysis of the inhibiting effect of antibiotic from the cephalosporin series, nanoencapsulated gellan and xanthan gum in comparison with native antibiotics was performed. Differences in the effect of drugs depending on concentration were studied as well as positive effect of prolongation of activity nanoencapsulated form in low concentration. The expediency of using gellan and xanthan gum nanoencapsulation of cephalosporin antibiotic was shown.","PeriodicalId":20489,"journal":{"name":"Proceedings of the 1st International Symposium Innovations in Life Sciences (ISILS 2019)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84649765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.2991/isils-19.2019.38
S. Kontsevaya, Svetkana Shambazova
—This article regards the problem topicality of goods traceability which State Veterinary Supervision controls within the territory of Russian Federation, this article regards the advantages of issuance electronic veterinary certificates by the Federal State Information System «Mercury». This article considers the legal aspects of the system mentioned above, analyzes offences which are identified by the Supervisory Authorities during the moving of the animal origin products.
{"title":"Electronic Certification as an Instrument of Effective Veterinary Control in the Turnover of Animal Origin Products","authors":"S. Kontsevaya, Svetkana Shambazova","doi":"10.2991/isils-19.2019.38","DOIUrl":"https://doi.org/10.2991/isils-19.2019.38","url":null,"abstract":"—This article regards the problem topicality of goods traceability which State Veterinary Supervision controls within the territory of Russian Federation, this article regards the advantages of issuance electronic veterinary certificates by the Federal State Information System «Mercury». This article considers the legal aspects of the system mentioned above, analyzes offences which are identified by the Supervisory Authorities during the moving of the animal origin products.","PeriodicalId":20489,"journal":{"name":"Proceedings of the 1st International Symposium Innovations in Life Sciences (ISILS 2019)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75975280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.2991/isils-19.2019.86
O. Yastrebova, I. Boyko, S. Kontsevaya, Alexander Dobudko, Viacheslav Syrovitskiy, P. Gorodov
The influence of "FITOS" BAA on the natural resistance of laying hens and their productivity was studied. It was found that it improves the physiological state of the chickens and increases egg production. Keywords— laying hens, egg production, protein metabolism, amino acids, red blood cells, feed conversion, "Fitos" BAA
{"title":"Expediency of \"FITOS\" BAA Nutritional Intervention in the Diet of Laying Hens","authors":"O. Yastrebova, I. Boyko, S. Kontsevaya, Alexander Dobudko, Viacheslav Syrovitskiy, P. Gorodov","doi":"10.2991/isils-19.2019.86","DOIUrl":"https://doi.org/10.2991/isils-19.2019.86","url":null,"abstract":"The influence of \"FITOS\" BAA on the natural resistance of laying hens and their productivity was studied. It was found that it improves the physiological state of the chickens and increases egg production. Keywords— laying hens, egg production, protein metabolism, amino acids, red blood cells, feed conversion, \"Fitos\" BAA","PeriodicalId":20489,"journal":{"name":"Proceedings of the 1st International Symposium Innovations in Life Sciences (ISILS 2019)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83490487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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