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Improvement of Drug Supply for Women with Climacteric Disorders 改善妇女更年期疾病的药物供应
I. Spichak, Tatyana Babanina, I. Zhirova
The article presents the results of improving the drug supply for women with menopausal disorders at the regional level. A sociological study of women with climacteric disorders as a consumer of pharmaceutical care has been conducted. Marketing analysis of the Russian and regional pharmaceutical markets for the prevention and treatment of menopausal disorders has been carried out; assessment of competitiveness of hormonal, homeopathic drugs and nutritional supplements for the prevention and treatment of menopausal disorders in women; proposals have been developed for pharmacies to formulate an assortment policy in the field of drug procurement for the prevention and treatment of menopausal disorders in women. Keywords—pharmaceutical market, climacteric disorders, menopause, medicines, sociological research, consumer preferences, compliance with therapy, marketing research, drug competitiveness
本文介绍了在区域一级改善绝经期疾病妇女药物供应的结果。一项社会学研究的妇女更年期障碍作为一个消费者的医药保健已进行。对预防和治疗更年期疾病的俄罗斯和区域医药市场进行了市场分析;评估激素、顺势疗法药物和营养补充剂在预防和治疗妇女更年期疾病方面的竞争力;已提出建议,要求药店在药品采购领域制订分类政策,以预防和治疗妇女更年期失调。关键词:医药市场,更年期障碍,更年期,药物,社会学研究,消费者偏好,依从性治疗,市场研究,药物竞争力
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引用次数: 0
Optimization of a Method for Obtaining and Determination of Carotenoids in Tambukan Mud 坦布坎泥中类胡萝卜素提取及含量测定方法的优化
D. Kompantsev, A. Chakhirova, T. Gutnova
— Therapeutic sulphide silt mud from Tambukan lake has been formed for a long period of time. Balneological value of silt mud from that specific lake is high because of high level of ferrous sulphides and water-soluble salts in it’s content, including recognized as therapeutically active bromine and boric acid; high concentration of lipids and carotenoids, which have anti-inflammatory, anti-bacteria, immune stimulating and bio stimulating effects. Goal: development of the method for stimulation of the peloid extract obtaining process from the Tambukan mud by an ultrasound-assisted extraction with further determination of biologically active substance using a spectrophotometric method. The research is based on formerly known and patented methods, offered by Kh.G.Karagulov. The method is reasonable, allows to extract carotenoid in full. The disadvantage of it is the energy-demanding and the usage of an organic solvent. As the object of the research a deep seated mud sample from the Tambukan lake was taken. After an ultrasound-assisted extraction there was obtained an oily extract from the mud sample. Quantitative content estimation was held out using a spectrophotometric method in visible region of absorption. The ability to optimize the process of peloid extraction from the Tambukan mud by the ultrasound-assisted extraction has been proven. Offered method for extraction and determination of carotenoid amount in Tambukan mud is less resource- and energy-demanding. Alongside with that it provides best possible carotenoid amount in the outcome. Effective and less expensive method to obtain peloid from Tambukan mud has been developed. The research results point out that the level of carotenoids in Tambukan silt mud has been reduced resulting in serious reduction of therapeutic effect. in
-坦布坎湖的治疗性硫化物淤泥已经形成了很长一段时间。该湖淤泥中硫化铁和水溶性盐含量高,包括具有治疗活性的溴和硼酸,因此淤泥的生物学价值很高;高浓度脂类及类胡萝卜素,具有抗炎、抗菌、免疫刺激及生物刺激作用。目的:建立超声辅助提取法对坦布坎泥类提取物提取工艺的刺激,并进一步采用分光光度法测定生物活性物质。这项研究是基于karagulov提供的以前已知和专利的方法。方法合理,可充分提取类胡萝卜素。它的缺点是能源需求和使用有机溶剂。研究对象为坦布坎湖深层泥样。超声辅助萃取后,从泥浆样品中获得了一种油性萃取物。用分光光度法在可见吸收区进行了定量含量估计。研究结果表明,超声辅助提取法可以优化坦布坎泥质体的提取工艺。提出的提取和测定坦布坎泥中类胡萝卜素含量的方法对资源和能量的要求较低。与此同时,它提供了最好的类胡萝卜素量的结果。开发了一种从坦布坎泥浆中提取似球粒的有效而经济的方法。研究结果表明,坦布坎淤泥中类胡萝卜素含量降低,导致治疗效果严重下降。在
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引用次数: 0
Methodical Approach to Carrying out a Multi-Aspect Examination of Pharmaceutical Products 对药品进行多方面检验的方法研究
Y. Dereglazova, I. Spichak, E. Kaliuzhnaya
The article presents the developed methodological approach to the technology of conducting a multi-aspect examination of the range of pharmaceutical products. This approach may be of interest for optimizing the prescription of pharmaceutical products by doctors in medical organizations during the pharmacotherapy of patients with various nosologies in the conditions of outpatient and inpatient treatment Keywords—pharmaceutical assistance, pharmaceutical products, comprehensive pharmacoeconomic research, multidimensional assortment expertise
文章提出了发展的方法学方法的技术进行多方面的检查范围的医药产品。该方法可用于优化医疗机构医生在门诊和住院治疗条件下对不同疾病的患者进行药物治疗时的药品处方。关键词:药物援助,药品,综合药物经济学研究,多维分类专业知识
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引用次数: 0
Variability Parameters of Strigunovsky Local Variety of Bulb Onion 斯特里古诺夫斯基地方洋葱品种的变异参数
N. Kotsareva, O. Shabetya, A. Kryukov
—The results of selection work for restoring the varietal qualities of Strigunovsky local varieties of bulb onion. 7 promising lines of onions with stable varietal qualities, such as the shape and color of the bulbs, the yield of bulbs and seed productivity were obtained.
——斯特里格诺夫斯基地方洋葱品种品质恢复选育工作的结果。获得了7个具有稳定品种品质的洋葱品系,如鳞茎形状和颜色、鳞茎产量和种子产量。
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引用次数: 0
Exopolysaccharide Fermented Milk Ice Cream 外多糖发酵乳冰淇淋
E. Pozhidaeva, E. Popov, Yana Dymovskih
—Currently, there is an increasing interest in exopolysaccharides as effective biocorrector and auxiliary technological agents. Experimental studies were carried out to obtain fermented milk ice cream with a high content of exopolysaccharides. As a nutrient substrate for the cultivation of probiotic microorganisms, a mixture was used to obtain ice cream, including dairy and non-dairy components. The starter cultures included certain strains of microorganisms: Streptococcus thermophilus, Lactobacillus delbrueckii ssp. bulgaricus. It was experimentally established that ice-cream with the addition of a bacterial starter culture YO-PROX 777, including thermophilic lactic acid strains of the microorganisms Streptococcus thermophiles, Lactobacillus delbrueckii ssp, has the greatest ssp. bulgaricus. It was established that the highest concentration of exopolysaccharides is contained in ice cream using the starter culture «YO-PROX 777».
-目前,人们对胞外多糖作为有效的生物校正剂和辅助技术剂的兴趣越来越大。为获得高外多糖含量的发酵乳冰淇淋,进行了实验研究。作为益生菌微生物培养的营养基质,一种混合物被用来获得冰淇淋,包括乳制品和非乳制品成分。发酵剂包括某些菌株的微生物:嗜热链球菌,德氏乳杆菌。发酵剂。保加利亚实验结果表明,添加细菌发酵剂YO-PROX 777(含嗜热乳酸链球菌、德氏乳杆菌)的冰淇淋具有最高的发酵剂效果。发酵剂。保加利亚经证实,使用发酵剂“YO-PROX 777”的冰淇淋中含有最高浓度的胞外多糖。
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引用次数: 0
Opportunities for Using of Eleutherococcuses Fruits as a New Food Raw Material 刺棘球菌果实作为一种新的食品原料的利用机遇
E. Solomonova, N. Trusov, T. Nozdrina
The purpose of study is to identify possibilities of using fruits of eleutherococcuses Eleutherococcus senticosus Rupr. & Maxim. аnd Eleutherococcus sessiliflorus Rupr. & Maxim., which are undergoing introduction tests in arboretum of N.V. Tsytsin Main Botanical Garden of Russian Academy of Science, as easily renewable biosafety drug and food resource. By standard methods, comparative morphology-anatomical and morphometric study of fruits was carried out; content of air-dry, absolutely-dry substance and ascorbic acid was determined in them; statistical processing of the results was performed. The fleshy drupes that we studied vary in fruits shape, by number, shape and size of stones. Features and similarities of anatomical structure of exocarp, mesocarp and endocarp of fruits, typical for most members of the Araliaceae family, were revealed. Fresh fruits of E. senticosus are smaller and lighter than fruits of E. sessiliflorus, but surpass them in terms of volume of stones and amount of ascorbic acid; content of absolutely-dry matter in them is equally high. We propose to consider fruits of both types as a new promising raw material for the production of biologically active additives and functional foods, alternative to traditional raw materials from roots of eleutherococcuses, traumatic to the plants. Keywords—eleutherococcus, morphology-anatomical structure, morphometric parameters, air-dry mass, absolutelydry matter, vitamin C
本研究的目的是确定利用刺刺球菌果实的可能性。和格言。无梗棘球绦虫;和格言。,作为易再生的生物安全药物和食品资源,正在俄罗斯科学院叶利钦主要植物园进行引种试验。采用标准方法,对果实进行了形态解剖学和形态计量学的比较研究;测定了其中风干物质、绝对干物质和抗坏血酸的含量;对结果进行统计处理。我们研究的肉质核果在果实形状、数量、形状和核的大小上各不相同。揭示了五加科植物果实的外果皮、中果皮和内果皮解剖结构的特征和相似性。猕猴桃果实比无梗花果实体积小、重量轻,但在果核体积和抗坏血酸含量方面超过了猕猴桃果实;其中绝对干物质的含量也同样高。我们建议将这两种水果作为生产生物活性添加剂和功能食品的新原料,替代传统的对植物有害的刺虫根原料。关键词:棘球球菌,形态解剖结构,形态计量参数,风干质量,绝对干物质,维生素C
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引用次数: 3
Properties of Nanostuctured Motherwort Extract and Its Application in Fruit Jelly Candy Production 纳米益母草提取物的性质及其在果冻糖生产中的应用
A. Krolevets, N. Myachikova, K. Semichev
— The research paper includes the information on the application of nanostructured motherwort extract in the production of fruit jelly candy, which can be used as a therapeutic functional food product. The size of nanostructured motherwort extract was determined by a nanoparticle tracking analysis (NTA). It depended on a shell nature significantly.
-该研究报告包括纳米结构益母草提取物在生产果冻糖中的应用信息,可作为治疗功能食品使用。采用纳米颗粒跟踪分析(NTA)测定了纳米结构益母草提取物的粒径。它很大程度上取决于壳层性质。
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引用次数: 1
Antimicrobial Activity of Native and Nanoencapsulated Cephalosporin Antibiotics 原生和纳米包封头孢菌素类抗生素的抑菌活性
V. Klyueva, A. Sirotin, Elisaveta Rypalenko, Khristina Ozarko, Khristina Degtyareva
—The analysis of the inhibiting effect of antibiotic from the cephalosporin series, nanoencapsulated gellan and xanthan gum in comparison with native antibiotics was performed. Differences in the effect of drugs depending on concentration were studied as well as positive effect of prolongation of activity nanoencapsulated form in low concentration. The expediency of using gellan and xanthan gum nanoencapsulation of cephalosporin antibiotic was shown.
-分析了头孢菌素系列抗生素、纳米结冷胶和黄原胶与天然抗生素的抑制作用。研究了不同浓度下药物作用的差异,以及低浓度下纳米胶囊形式延长活性的积极作用。证明了用结冷胶和黄原胶纳米包封头孢菌素类抗生素的方便性。
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引用次数: 1
Electronic Certification as an Instrument of Effective Veterinary Control in the Turnover of Animal Origin Products 电子认证作为有效兽医控制动物源性产品周转的工具
S. Kontsevaya, Svetkana Shambazova
—This article regards the problem topicality of goods traceability which State Veterinary Supervision controls within the territory of Russian Federation, this article regards the advantages of issuance electronic veterinary certificates by the Federal State Information System «Mercury». This article considers the legal aspects of the system mentioned above, analyzes offences which are identified by the Supervisory Authorities during the moving of the animal origin products.
-本文讨论了俄罗斯联邦境内国家兽医监督管理的货物可追溯性问题,本文讨论了联邦国家信息系统“水银”签发电子兽医证书的优势。本文考虑了上述系统的法律方面,分析了监管机构在动物源性产品移动过程中确定的违法行为。
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引用次数: 0
Expediency of "FITOS" BAA Nutritional Intervention in the Diet of Laying Hens “FITOS”BAA营养干预蛋鸡日粮的可行性
O. Yastrebova, I. Boyko, S. Kontsevaya, Alexander Dobudko, Viacheslav Syrovitskiy, P. Gorodov
The influence of "FITOS" BAA on the natural resistance of laying hens and their productivity was studied. It was found that it improves the physiological state of the chickens and increases egg production. Keywords— laying hens, egg production, protein metabolism, amino acids, red blood cells, feed conversion, "Fitos" BAA
研究了“FITOS”BAA对蛋鸡自然抗性和产蛋率的影响。研究发现,它能改善鸡的生理状态,提高产蛋量。关键词:蛋鸡,产蛋量,蛋白质代谢,氨基酸,红细胞,饲料转化,“Fitos”BAA
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引用次数: 2
期刊
Proceedings of the 1st International Symposium Innovations in Life Sciences (ISILS 2019)
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