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Investigation of the dosimetric properties of K2SO4:Cu,Na detectors with varying phosphor and binder content using infrared-stimulated luminescence (IRSL) 红外激发发光(IRSL)研究不同荧光粉和结合剂含量的K2SO4:Cu,Na探测器的剂量学性质
IF 2.2 3区 物理与天体物理 Q2 NUCLEAR SCIENCE & TECHNOLOGY Pub Date : 2025-12-28 DOI: 10.1016/j.radmeas.2025.107603
Renata Majgier
K2SO4:Cu,Na is as a very sensitive phosphor for infrared stimulated luminescence (IRSL), and adding sodium as a co-dopant significantly enhances its dosimetric properties. This study focuses on the initial optimization of the K2SO4:Cu,Na phosphor for use as a passive detector with the IRSL method for reading dose information. Various detector configurations were prepared by mixing the phosphor powder with binders such as Teflon and silicone in different ratios. Key dosimetric characteristics: signal repeatability, dose-response, minimum detectable dose (MDD), and signal fading were evaluated. The dose-response relationship was found to be linear within the range of at least 3 mGy to 1 Gy. In several samples, the MDD was below 1 μGy. The material exhibited ∼50 % signal loss after three months of storage. To address this fading, preheating procedures before IRSL readout were tested, aiming to stabilize the IRSL signal over time. It was shown that preheating prevented signal loss for up to one month post-irradiation, and significantly reduced long-term fading compared to untreated samples. The results highlight the promising potential of K2SO4:Cu,Na phosphor in radiation dosimetry applications.
K2SO4:Cu,Na是一种对红外激发发光(IRSL)非常敏感的荧光粉,加入钠作为共掺杂剂可显著提高其剂量学性能。本研究主要研究了K2SO4:Cu,Na荧光粉作为被动检测器的初始优化,并采用IRSL方法读取剂量信息。将荧光粉与聚四氟乙烯、有机硅等粘结剂按不同比例混合,制备出不同的探测器结构。评估了关键的剂量学特征:信号可重复性、剂量反应、最小可检测剂量(MDD)和信号衰减。在至少3mgy至1gy的范围内,剂量-反应关系呈线性关系。在一些样品中,MDD低于1 μGy。该材料在储存三个月后表现出约50%的信号损失。为了解决这种衰减问题,在测试IRSL读数之前进行预热程序,旨在随着时间的推移稳定IRSL信号。研究表明,与未经处理的样品相比,预热可以防止辐射后长达一个月的信号损失,并显着减少长期褪色。结果表明,K2SO4:Cu,Na荧光粉在辐射剂量学方面具有广阔的应用前景。
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引用次数: 0
Performance evaluation in multi-radionuclide distribution measurement of a new SPECT system based on a thick CZT crystal 基于厚CZT晶体的新型SPECT多放射性核素分布测量系统的性能评价
IF 2.2 3区 物理与天体物理 Q2 NUCLEAR SCIENCE & TECHNOLOGY Pub Date : 2025-12-26 DOI: 10.1016/j.radmeas.2025.107602
Feng Tian , Changran Geng , Lijun Tang , Xiaobin Tang
Single photon emission computed tomography (SPECT) is the commonly used imaging modality in clinical nuclear medicine for disease diagnosis. However, traditional SPECT systems have several disadvantages when monitoring the distribution of radiopharmaceuticals labeled various radionuclides.
A cadmium zine telluride (CZT) SPECT system based on a 15.00 mm thick, three-dimensional (3D) pixeled CZT crystal is developed. The performance of this CZT-SPECT system in detecting the distribution of different radiopharmaceuticals are analyzed through mouse phantom experiments. The results show that for 99mTc (141 keV), 177Lu (208 keV), and 18F (511 keV), the energy resolution of the CZT-SPECT system is 2.38 %, 1.94 %, and 1.47 %, respectively. The depth of interaction (DOI) of 141 keV, 208 keV or 511 keV gamma rays emitted by different radionuclides in the CZT crystal are recorded, and the DOI ranges are approximately 2.17–5.85 mm, 2.00–9.00 mm, and 1.00–11.00 mm, respectively. Both qualitative and quantitative results indicate that the CZT-SPECT system can achieve spatial distribution detection and reconstruction, both in case of irradiation with only one and multiple radionuclides. The full width at half maximum (FWHM) of radiation source placed in each kidney reconstructed is almost less than 5.00 mm for these radionuclides.
Due to the excellent energy resolution and the large size of the 3D-CZT crystal, the CZT-SPECT system developed can effectively measure the in-vivo distribution of various diagnostic and therapeutic radiopharmaceuticals labeled with different radionuclides. The results of this study can also provide technical support for the future development of more radiopharmaceuticals.
单光子发射计算机断层扫描(SPECT)是临床核医学中常用的疾病诊断成像方式。然而,传统的SPECT系统在监测各种放射性核素标记的放射性药物分布时存在一些缺点。研制了一种基于15.00 mm厚三维像素化CZT晶体的碲化镉锌(CZT) SPECT系统。通过小鼠模拟实验,分析了该系统检测不同放射性药物分布的性能。结果表明,在99mTc (141 keV)、177Lu (208 keV)和18F (511 keV)条件下,CZT-SPECT系统的能量分辨率分别为2.38%、1.94%和1.47%。记录了不同放射性核素在CZT晶体中发射的141 keV、208 keV和511 keV伽马射线的相互作用深度(DOI), DOI范围分别约为2.17 ~ 5.85 mm、2.00 ~ 9.00 mm和1.00 ~ 11.00 mm。定性和定量结果表明,无论是单核素辐照还是多核素辐照,CZT-SPECT系统都能实现空间分布的检测和重建。这些放射性核素在重建的每个肾脏中放置的辐射源的半最大值全宽度(FWHM)几乎小于5.00 mm。由于3D-CZT晶体具有优异的能量分辨率和较大的尺寸,所开发的CZT-SPECT系统可以有效地测量不同放射性核素标记的各种诊断和治疗放射性药物的体内分布。本研究结果也可为未来更多放射性药物的开发提供技术支持。
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引用次数: 0
Towards a fully automated instrument for the advanced characterisation of trapped-charge luminescence signals: The NAUTILUS proof-of-concept 迈向用于捕获电荷发光信号高级表征的全自动仪器:NAUTILUS概念验证
IF 2.2 3区 物理与天体物理 Q2 NUCLEAR SCIENCE & TECHNOLOGY Pub Date : 2025-12-22 DOI: 10.1016/j.radmeas.2025.107601
Lily Bossin , Mads L. Jensen , Georgina E. King , Eduardo G. Yukihara
A Risø TL/OSL reader and a Horiba Fluorolog-QM spectrofluorometer were coupled using an optical fibre bundle to form a novel instrument, the Next-generation AUtomated Trapped charge Induced LUminescence Spectroscopy (NAUTILUS) instrument. The combined capabilities of the two instruments forming the NAUTILUS open up the possibility to perform a large range of luminescence measurements to characterise radiation-induced luminescence signals. The NAUTILUS can carry out sequences of irradiation, preheating, annealing, and advanced luminescence measurements, such as photoluminescence (PL) or radiophotoluminescence (RPL) spectroscopy, PL at elevated temperature, optically stimulated luminescence (OSL) stimulation and emission spectroscopy, and/or bleaching across the visible spectrum. The NAUTILUS also allows for nanosecond time-resolved PL or OSL measurement using pulsed lasers or diode light sources. These measurements can be carried sequentially on up to 48 samples without the need to move the samples between instruments, thus improving both measurement reproducibility and throughput.
The aim of this contribution is to demonstrate the capabilities of the NAUTILUS using well-known dosimetric materials, such as Al2O3:C,Mg, Al2O3:C, MgB4O7:Ce,Li, and Ag+-doped phosphate glass. By doing so, we demonstrate the NAUTILUS’ capability to perform in-situ irradiation, heating, and reliable advanced luminescence measurements, sequentially on up to 48 samples, with results in agreement with those reported in the literature.
使用光纤束将Risø TL/OSL读取器和Horiba fluorology - qm荧光光谱仪耦合在一起,形成了一种新型仪器,即下一代自动捕获电荷诱导发光光谱(NAUTILUS)仪器。组成NAUTILUS的两种仪器的综合能力为进行大范围的发光测量提供了可能性,以表征辐射引起的发光信号。NAUTILUS可以进行一系列的辐照、预热、退火和高级发光测量,例如光致发光(PL)或放射光致发光(RPL)光谱、高温下的PL、光激发发光(OSL)刺激和发射光谱,以及/或整个可见光谱的漂白。NAUTILUS还允许纳秒时间分辨PL或OSL测量使用脉冲激光或二极管光源。这些测量可以在多达48个样品上连续进行,而无需在仪器之间移动样品,从而提高了测量的可重复性和吞吐量。这项贡献的目的是展示NAUTILUS使用众所周知的剂量测定材料的能力,例如Al2O3:C,Mg, Al2O3:C, MgB4O7:Ce,Li和Ag+掺杂的磷酸盐玻璃。通过这样做,我们证明了NAUTILUS能够进行原位照射,加热和可靠的先进发光测量,依次对多达48个样品进行测量,结果与文献中报道的结果一致。
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引用次数: 0
Characterisation of LaCl3(Ce)-based detectors for D-D fusion neutron diagnostic 用于D-D聚变中子诊断的LaCl3(Ce)基探测器的表征
IF 2.2 3区 物理与天体物理 Q2 NUCLEAR SCIENCE & TECHNOLOGY Pub Date : 2025-12-19 DOI: 10.1016/j.radmeas.2025.107600
D.S. Fridrikhsen , S.Yu. Obudovsky , T.M. Kormilitsyn , A.V. Pankratenko , Yu.A. Kashchuk , N.N. Moiseev
This study presents an experimental evaluation of key parameters (efficiency and sensitivity) of two detectors based on lanthanum chloride LaCl3(Ce) scintillation crystals. We performed measurements in the neutron energy range of ∼2.2–2.9 MeV using a reference neutron source at the D.I. Mendeleyev Institute for Metrology in St. Petersburg, Russia. A special feature of the source is the thin target (mitigating internal neutron attenuation), the total D-D neutron yield is ∼2 × 106 n/s. The values for the sensitivity obtained from the experiment were underestimated by a factor of several times compared to those calculated using cross-sections from the ENDF/B-VIII.0 nuclear data library. These results suggest a possible need to refine the properties of the 35Cl(n,p)35Sg.s. reaction used in the evaluation model and to supplement the database with experimental data in the neutron energy region of ∼2.5 MeV.
本文对两种基于氯化镧LaCl3(Ce)闪烁晶体的探测器的关键参数(效率和灵敏度)进行了实验评估。我们在俄罗斯圣彼得堡D.I.门捷列夫计量研究所使用参考中子源进行了中子能量范围为~ 2.2-2.9 MeV的测量。该源的一个特点是薄靶(减轻内部中子衰减),总D-D中子产率为~ 2 × 106 n/s。与使用ENDF/B-VIII的横截面计算的灵敏度值相比,从实验中获得的灵敏度值被低估了几倍。0核数据库。这些结果表明可能需要改进35Cl(n,p)35Sg.s的性能。在评价模型中使用的反应,并补充数据库中在~ 2.5 MeV的中子能量区域的实验数据。
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引用次数: 0
Corrigendum to “Characterization of a Gd-based color CMOS detector for proton dosimetry” [Radiat. Meas. 164 (2023) 106945] “质子剂量测定中基于钆的彩色CMOS探测器的表征”的勘误表[Radiat]。平均数。164 (2023)106945]
IF 2.2 3区 物理与天体物理 Q2 NUCLEAR SCIENCE & TECHNOLOGY Pub Date : 2025-12-18 DOI: 10.1016/j.radmeas.2025.107595
Qi Liu , Benno Rohrer , Sairos Safai , Antony John Lomax , Zhiling Chen , Michele Togno
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引用次数: 0
Absolute measurement of absorbed dose in water for 125I brachytherapy seeds 125I近距离放射治疗种子在水中吸收剂量的绝对测量
IF 2.2 3区 物理与天体物理 Q2 NUCLEAR SCIENCE & TECHNOLOGY Pub Date : 2025-12-18 DOI: 10.1016/j.radmeas.2025.107594
Zhong-Bin Hang , Chuan-Feng Liu , Yan Zhang , Zi-Wei Liang , Hai Hu , Tian-Tian Zhang , Yun-Tao Liu , Ming-Zhe Song , Ke-Xin Wei , Lin Qin , Xi-Mei Wang , Zuo-Xiang He

Background:

In the clinical application of brachytherapy, the relevant quantities of brachytherapy seed strength must be converted into absorbed dose at a reference depth of 1 cm in water. The current method of obtaining the absorbed dose in water is based on the air kerma strength and dose rate constant, which has an uncertainty of more than 10% (k=2), potentially affecting cancer treatment outcomes.

Purpose:

To ensure accurate dosimetry for 125I brachytherapy seeds, an extrapolation chamber embedded in the water-equivalent material was designed and manufactured to measure the absorbed dose in water directly.

Methods:

The mathematical model for determining the absorbed dose in water is based on radiation transport theory, where the key term conversion factor C(xi+1,xi) is determined using the Monte Carlo (MC) methods. In this paper, the basic structure, the measurement method, and the MC simulation of the extrapolation chamber are described. The dose rate constant of the model 6711 125I brachytherapy seed was obtained using three methods (experimental measurement, MC simulation, and AAPM recommended values), and the results was compared and analyzed.

Results:

The absorbed dose in water of the model 6711 125I brachytherapy seed was determined, and after repeated measurements and uncertainty evaluation, the result was 12.39 mGy/h, with an uncertainty of 3.5% (k=2). In addition, the brachytherapy seed was calibrated using an absolute measurement device for the air kerma strength, and its dose rate constant was calculated, which was in good agreement with both the AAPM-recommended values and MC simulated values.

Conclusions:

We successfully developed an absolute measurement device for the absorbed dose in water, which reduced the measurement uncertainty for 125I brachytherapy seeds and achieved dose accuracy for external radiotherapy. This study contributes to the establishment of primary standards for the absorbed dose in water of 125I brachytherapy seeds.
背景:在近距离放射治疗的临床应用中,必须在水中参考深度1cm处将相关量的近距离放射治疗种子强度转换为吸收剂量。目前获取水中吸收剂量的方法是基于空气可汗强度和剂量率常数,其不确定度大于10% (k=2),可能影响癌症治疗效果。目的:为保证125I近距离放射治疗种子剂量测定的准确性,设计并制造了嵌入水当量材料的外推室,用于直接测量125I近距离放射治疗种子在水中的吸收剂量。方法:确定水中吸收剂量的数学模型基于辐射输运理论,其中关键项转换因子C(xi+1,xi)采用蒙特卡罗(MC)方法确定。本文介绍了外推室的基本结构、测量方法和MC模拟。采用实验测量、MC模拟和AAPM推荐值三种方法获得6711 125I型近距离放射治疗种子的剂量率常数,并对结果进行比较分析。结果:测定了6711 125I模型近距离放疗种子在水中的吸收剂量,经过反复测量和不确定度评定,结果为12.39 mGy/h,不确定度为3.5% (k=2)。此外,使用空气粒子强度绝对测量装置对近距离治疗粒子进行校准,并计算其剂量率常数,与aapm推荐值和MC模拟值吻合较好。结论:研制成功的水中吸收剂量绝对测量装置,降低了125I近距离放射治疗粒子的测量不确定度,达到了体外放疗的剂量准确性。本研究有助于建立125I近距离放射治疗种子在水中吸收剂量的初步标准。
{"title":"Absolute measurement of absorbed dose in water for 125I brachytherapy seeds","authors":"Zhong-Bin Hang ,&nbsp;Chuan-Feng Liu ,&nbsp;Yan Zhang ,&nbsp;Zi-Wei Liang ,&nbsp;Hai Hu ,&nbsp;Tian-Tian Zhang ,&nbsp;Yun-Tao Liu ,&nbsp;Ming-Zhe Song ,&nbsp;Ke-Xin Wei ,&nbsp;Lin Qin ,&nbsp;Xi-Mei Wang ,&nbsp;Zuo-Xiang He","doi":"10.1016/j.radmeas.2025.107594","DOIUrl":"10.1016/j.radmeas.2025.107594","url":null,"abstract":"<div><h3>Background:</h3><div>In the clinical application of brachytherapy, the relevant quantities of brachytherapy seed strength must be converted into absorbed dose at a reference depth of 1 cm in water. The current method of obtaining the absorbed dose in water is based on the air kerma strength and dose rate constant, which has an uncertainty of more than 10% (<em>k</em>=2), potentially affecting cancer treatment outcomes.</div></div><div><h3>Purpose:</h3><div>To ensure accurate dosimetry for <sup>125</sup>I brachytherapy seeds, an extrapolation chamber embedded in the water-equivalent material was designed and manufactured to measure the absorbed dose in water directly.</div></div><div><h3>Methods:</h3><div>The mathematical model for determining the absorbed dose in water is based on radiation transport theory, where the key term conversion factor <span><math><mrow><mi>C</mi><mrow><mo>(</mo><msub><mrow><mi>x</mi></mrow><mrow><mi>i</mi><mo>+</mo><mn>1</mn></mrow></msub><mo>,</mo><msub><mrow><mi>x</mi></mrow><mrow><mi>i</mi></mrow></msub><mo>)</mo></mrow></mrow></math></span> is determined using the Monte Carlo (MC) methods. In this paper, the basic structure, the measurement method, and the MC simulation of the extrapolation chamber are described. The dose rate constant of the model 6711 <sup>125</sup>I brachytherapy seed was obtained using three methods (experimental measurement, MC simulation, and AAPM recommended values), and the results was compared and analyzed.</div></div><div><h3>Results:</h3><div>The absorbed dose in water of the model 6711 <sup>125</sup>I brachytherapy seed was determined, and after repeated measurements and uncertainty evaluation, the result was 12.39 mGy/h, with an uncertainty of 3.5% (<em>k</em>=2). In addition, the brachytherapy seed was calibrated using an absolute measurement device for the air kerma strength, and its dose rate constant was calculated, which was in good agreement with both the AAPM-recommended values and MC simulated values.</div></div><div><h3>Conclusions:</h3><div>We successfully developed an absolute measurement device for the absorbed dose in water, which reduced the measurement uncertainty for <sup>125</sup>I brachytherapy seeds and achieved dose accuracy for external radiotherapy. This study contributes to the establishment of primary standards for the absorbed dose in water of <sup>125</sup>I brachytherapy seeds.</div></div>","PeriodicalId":21055,"journal":{"name":"Radiation Measurements","volume":"191 ","pages":"Article 107594"},"PeriodicalIF":2.2,"publicationDate":"2025-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145787322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimized quantitative indirect neutron radiography method for 2D non-primary radiation measurement in BNCT 优化定量间接中子放射成像方法用于BNCT二维非一次辐射测量
IF 2.2 3区 物理与天体物理 Q2 NUCLEAR SCIENCE & TECHNOLOGY Pub Date : 2025-12-18 DOI: 10.1016/j.radmeas.2025.107599
Jialong Yang , Xingyan Liu , Diyun Shu , Changran Geng , Xiaobin Tang , Yuan-Hao Liu
Accurate quantitative measurement of neutron non-primary radiation is crucial for the safe implementation of boron neutron capture therapy (BNCT), yet such measurement faces challenges including large measurement area and strong γ-ray interference. Indirect neutron radiography (INR) offers advantages for large-area measurement and γ resistance, but its application is limited by the low sensitivity of activation detectors and measurement errors from crosstalk. To address these challenges, dysprosium (Dy) was selected as the activation detector to enhance sensitivity, establishing a quantitative calibration relationship between its activity and imaging plate (IP) signals. For signal crosstalk during foil exposure, spatial convolution kernel was constructed using Monte Carlo simulations, and then applied with the Biconjugate Gradient Stabilized (Bi-CGSTAB) algorithm to perform spatial deconvolution of dose deposition on the IP, thereby reconstructing the actual activity of each pixel on the foil. Validation experiments demonstrated significant improvement, and the proportion of data points exceeding 5 % deviation decreased from over 60 % before correction to below 15 % after correction. Applied to clinical BNCT device, it successfully obtained the two-dimensional (2D) distribution of neutron non-primary radiation within 150–550 mm from the radiation field edge. The converted maximum skin absorbed dose rate was 1.26 × 10−4 Gy/s, located at 150 mm from the radiation field edge and decaying rapidly with increasing distance. This study achieved the quantitative measurement of 2D neutron non-primary radiation distribution in clinical BNCT devices, and provided technical support for comprehensive assessment of radiation risks and optimization of protection design.
中子非一次辐射的精确定量测量对于硼中子俘获治疗(BNCT)的安全实施至关重要,但这种测量面临着测量面积大、γ射线干扰强等挑战。间接中子射线照相(INR)具有大面积测量和抗γ的优点,但其应用受到激活探测器灵敏度低和串扰测量误差的限制。为了解决这些挑战,我们选择镝(Dy)作为激活探测器来提高灵敏度,并在其活度和成像板(IP)信号之间建立定量校准关系。针对箔暴露过程中的信号串扰,利用蒙特卡罗模拟构建空间卷积核,然后利用双共轭梯度稳定(Bi-CGSTAB)算法对IP上的剂量沉积进行空间反卷积,从而重建箔上每个像素的实际活动。验证实验证明了显著的改进,偏差超过5%的数据点比例从校正前的60%以上下降到校正后的15%以下。应用于临床BNCT装置,成功获得了距离辐射场边缘150 ~ 550 mm范围内的中子非一次辐射二维(2D)分布。转换最大皮肤吸收剂量率为1.26 × 10−4 Gy/s,位于距离辐射场边缘150mm处,随距离的增加而迅速衰减。本研究实现了临床BNCT装置中二维中子非一次辐射分布的定量测量,为辐射风险的综合评估和防护设计的优化提供技术支持。
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引用次数: 0
Deep learning-based organ dose prediction in pediatric head CT using fully automated tissue segmentation and newly developed voxelized phantoms in GATE/Geant4 simulation toolkit 基于深度学习的儿童头部CT器官剂量预测,使用全自动组织分割和GATE/Geant4模拟工具包中新开发的体素化模型
IF 2.2 3区 物理与天体物理 Q2 NUCLEAR SCIENCE & TECHNOLOGY Pub Date : 2025-12-17 DOI: 10.1016/j.radmeas.2025.107597
H. Sekkat , A. Khallouqi , O. El rhazouani , A. Halimi
This study evaluates the performance of a deep learning model developed to predict organ-specific radiation doses in pediatric head CT scans. The model automates tissue segmentation and voxelization of organs for Monte Carlo (MC) simulations, which provide the ground truth for dose assessment. Using a Python-based framework, the model preprocesses DICOM images, applies HU-based thresholds for tissue classification, and refines segmentation with morphological operations. The segmented tissues, bone, brain matter, eye lens and air + fat, are reconstructed into 3D voxelized volumes, enabling precise dose predictions. A convolutional neural network (CNN) with a pre-trained VGG16 architecture was employed to predict doses based on features extracted from the CT scans and voxelized phantoms. The dataset included 982 pediatric CT scans, with data augmentation techniques applied for model robustness. The model demonstrated high performance in predicting radiation doses, closely matching the MC simulated doses for all organs, with minimal deviations in mean doses and low standard deviations. RRMSE values were low (4.84 % for bone, 6.01 % for brain matter, 8.45 % for air + fat, and 10.59 % for eye lens), indicating high precision. Additionally, the model achieved high R2 values, with bone showing the best correlation (0.95). Performance analysis across 15 random allocations revealed that bone consistently exhibited the highest prediction accuracy, with the lowest median RRMSE (7.84 %) and median MAPE (1.2 %). Although variability was higher for brain matter, eye lens, and air + fat, bone demonstrated superior consistency and accuracy. In conclusion, the deep learning model effectively predicts organ-specific radiation doses for pediatric head CT scans, with particularly high accuracy for bone tissue. While the model shows reliable performance across multiple metrics, further optimization is needed for tissues with higher variability, indicating its promising potential in enhancing radiation dose assessment in pediatric CT.
本研究评估了用于预测儿童头部CT扫描中器官特异性辐射剂量的深度学习模型的性能。该模型为蒙特卡罗(MC)模拟自动组织分割和器官体素化,为剂量评估提供了基础真实性。该模型使用基于python的框架对DICOM图像进行预处理,应用基于hu的阈值进行组织分类,并使用形态学操作对分割进行细化。分割的组织,骨,脑物质,眼晶状体和空气+脂肪,被重建成三维体素体积,实现精确的剂量预测。采用预训练VGG16结构的卷积神经网络(CNN)根据CT扫描和体素化幻象提取的特征预测剂量。数据集包括982个儿童CT扫描,数据增强技术应用于模型稳健性。该模型在预测辐射剂量方面表现出很高的性能,与MC模拟的所有器官的辐射剂量密切匹配,平均剂量偏差最小,标准偏差低。RRMSE值较低(骨骼为4.84%,脑物质为6.01%,空气+脂肪为8.45%,晶状体为10.59%),表明精度较高。此外,该模型获得了较高的R2值,与骨的相关性最好(0.95)。15个随机分配的性能分析显示,骨骼始终表现出最高的预测准确性,中位RRMSE(7.84%)和中位MAPE(1.2%)最低。尽管脑物质、眼球晶状体和空气+脂肪的可变性更高,但骨骼表现出更好的一致性和准确性。总之,深度学习模型有效地预测了儿童头部CT扫描的器官特异性辐射剂量,对骨组织的准确性特别高。虽然该模型在多个指标上都表现出可靠的性能,但对于具有较高可变性的组织,还需要进一步优化,这表明该模型在加强儿童CT辐射剂量评估方面具有很大的潜力。
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引用次数: 0
Application of combined EPR alanine/OSL Al2O3:C dosimetry for neutron and photon dose measurements EPR丙氨酸/OSL Al2O3:C复合剂量法在中子和光子剂量测量中的应用
IF 2.2 3区 物理与天体物理 Q2 NUCLEAR SCIENCE & TECHNOLOGY Pub Date : 2025-12-17 DOI: 10.1016/j.radmeas.2025.107598
A. Romanyukha , J.L. Saunders , J.A. Delzer , A. Smolinski , K. Riley , A. Guynn , A. Tsioplaya , A. Cook
Alanine Electron Paramagnetic Resonance (EPR) dosimetry can measure the total (neutron + photon) dose from a neutron source. Commercially available optically stimulated luminescence (OSL) dosimeters and readers can accurately measure photon doses. An independent measurement of the photon dose contribution is vital because alanine has a different sensitivity to neutrons and photons when calibrated in terms of tissue kerma from 60Co gamma radiation. Therefore, OSL dosimetry can be used to separate neutron and photon dose contributions from the total dose measured by alanine. The Armed Forces Radiobiology Research Institute (AFRRI) research reactor produces varied neutron-photon mixtures, primarily used for radiobiology experiments. Many phantoms at AFRRI are used to measure the accuracy of dose delivery in animal experiments. In the present work, standard and 3D-printed rat phantoms equipped with OSL and alanine dosimeters were used. A special holder capable of securing four alanine pellets and four OSL NanoDot dosimeters was designed and 3D-printed and inserted into the rat phantoms during irradiation. This work was aimed at comparing 3D-printed rat phantoms with the standard PMMA phantom. The results of neutron and photon dose measurements after irradiation in different photon and neutron mixtures are presented. Based on these measurements, the relative neutron sensitivity of alanine was determined to be 0.35 ± 0.11 Gy. Alanine neutron dose measurements were validated using other dosimetry techniques, and further applications of the developed approach are discussed.
丙氨酸电子顺磁共振(EPR)剂量法可以测量中子源的总(中子+光子)剂量。市售的光激发发光(OSL)剂量计和读取器可以精确测量光子剂量。光子剂量贡献的独立测量是至关重要的,因为丙氨酸对中子和光子的灵敏度不同,当根据60Co伽马辐射的组织角度进行校准时。因此,OSL剂量法可以从丙氨酸测量的总剂量中分离出中子和光子的剂量贡献。武装部队放射生物学研究所(AFRRI)研究反应堆产生各种中子-光子混合物,主要用于放射生物学实验。在动物实验中,AFRRI的许多模型被用来测量给药的准确性。本研究采用标准大鼠模型和3d打印大鼠模型,分别配备OSL和丙氨酸剂量计。设计了一个特殊的支架,能够固定四个丙氨酸颗粒和四个OSL纳米点剂量计,并通过3d打印并在照射期间插入大鼠的幻影中。这项工作旨在比较3d打印的大鼠幻影与标准PMMA幻影。介绍了在不同的光子和中子混合物中辐照后的中子和光子剂量测量结果。根据这些测量,确定丙氨酸的相对中子灵敏度为0.35±0.11 Gy。用其他剂量学技术验证了丙氨酸中子剂量测量,并讨论了所开发方法的进一步应用。
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引用次数: 0
Pulsed and time-resolved optically stimulated luminescence of natural minerals – A review 天然矿物的脉冲和时间分辨光激发发光。综述
IF 2.2 3区 物理与天体物理 Q2 NUCLEAR SCIENCE & TECHNOLOGY Pub Date : 2025-12-16 DOI: 10.1016/j.radmeas.2025.107596
Svenja Riedesel , Christina Ankjærgaard
Time-resolved luminescence measurements provide a powerful means of investigating luminescence processes across timescales, ranging from picoseconds to seconds. These measurements are typically enabled by pulsed stimulation, where light pulses of fixed durations are applied to a sample. Luminescence can then be recorded both during and after the pulsed light stimulation, allowing discrimination between stimulation and emission, as well as isolation of luminescence components with different lifetimes.
Quartz and feldspar minerals are the two natural minerals most commonly used in luminescence studies. Time-resolved luminescence of feldspars has been investigated since the early 1990s, while quartz time-resolved signals has come into focus since around 2000. Over the past three decades, the extensive research into time-resolved and pulsed luminescence properties of these two minerals has provided insights into the lifetime of recombination and relaxation processes of various emissions in these minerals. These differences in the luminescence decay of quartz and feldspar offers a practical solution for discriminating their luminescence.
This review is aimed at researchers specialising in the field of luminescence dating, who embark on their first pulsed and time-resolved luminescence journeys. It provides practical information on measurement techniques for conducting time-resolved luminescence measurements and presents an overview of research findings, accumulated over the past 3.5 decades highlighting both the fundamental processes revealed and the applications enabled by these methods.
时间分辨发光测量提供了一种强大的方法来研究从皮秒到秒的时间尺度上的发光过程。这些测量通常是通过脉冲刺激实现的,其中固定持续时间的光脉冲应用于样品。然后可以在脉冲光刺激期间和之后记录发光,允许区分刺激和发射,以及具有不同寿命的发光成分的隔离。石英和长石矿物是发光研究中最常用的两种天然矿物。长石的时间分辨发光自20世纪90年代初开始研究,而石英的时间分辨信号自2000年左右开始成为焦点。在过去的三十年中,对这两种矿物的时间分辨和脉冲发光特性的广泛研究,为这些矿物中各种发射的重组和弛豫过程的寿命提供了见解。石英和长石在发光衰减方面的差异为区分它们的发光提供了一种实用的方法。这篇综述是针对专门从事发光测年领域的研究人员,他们开始了他们的第一次脉冲和时间分辨发光之旅。它提供了有关进行时间分辨发光测量的测量技术的实用信息,并概述了过去35年来积累的研究成果,重点介绍了这些方法所揭示的基本过程和应用。
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Radiation Measurements
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