Pub Date : 2016-05-15DOI: 10.1109/MeMeA.2016.7533783
P. Marconi, E. Pessa, M. P. Penna, R. Tambelli
Brain Dynamics seems to be the most actual approach to the brain responses to external stimuli. Even if Event Related Potentials can be detected, the EEG band power perturbation and the Phase Amplitude Coupling (PAC) seems to be the most appropriate way to assess such a brain dynamics. In this study 13 borderline subject with a child maltreatment history were studied in respect to 11 controls without any psychopathologic history. Both group were exposed to the Odd Ball Paradigm and related EEG activities were recorded from 256 electrodes on the scalp. The maltreated people resulted in higher levels of dystimia and worst behavioral performances as well as with a higher emotional dysregulation. Electro-physiological correlates were assessed with a different brain dynamics detected in maltreated group when target stimuli were presented. The results confirm the importance of the PAC and of the assessment of Cross Frequency Modulation (CfM). The results support the role of such a method for clinical diagnostics and suggest an explanation for the use of brain entrainment effect for therapeutic interventions. More over the presence of these oscillatory phenomena and this kind of brain dynamics suggest the compatibility of such results with scale free structures in the brain network architectures, where a small number of hubs, with high connection degrees, are embedded within a large assembly of neurons with low connection degrees.
{"title":"The phase amplitude coupling to assess brain network system integration","authors":"P. Marconi, E. Pessa, M. P. Penna, R. Tambelli","doi":"10.1109/MeMeA.2016.7533783","DOIUrl":"https://doi.org/10.1109/MeMeA.2016.7533783","url":null,"abstract":"Brain Dynamics seems to be the most actual approach to the brain responses to external stimuli. Even if Event Related Potentials can be detected, the EEG band power perturbation and the Phase Amplitude Coupling (PAC) seems to be the most appropriate way to assess such a brain dynamics. In this study 13 borderline subject with a child maltreatment history were studied in respect to 11 controls without any psychopathologic history. Both group were exposed to the Odd Ball Paradigm and related EEG activities were recorded from 256 electrodes on the scalp. The maltreated people resulted in higher levels of dystimia and worst behavioral performances as well as with a higher emotional dysregulation. Electro-physiological correlates were assessed with a different brain dynamics detected in maltreated group when target stimuli were presented. The results confirm the importance of the PAC and of the assessment of Cross Frequency Modulation (CfM). The results support the role of such a method for clinical diagnostics and suggest an explanation for the use of brain entrainment effect for therapeutic interventions. More over the presence of these oscillatory phenomena and this kind of brain dynamics suggest the compatibility of such results with scale free structures in the brain network architectures, where a small number of hubs, with high connection degrees, are embedded within a large assembly of neurons with low connection degrees.","PeriodicalId":221120,"journal":{"name":"2016 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114416789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-05-15DOI: 10.1109/MeMeA.2016.7533734
S. Rosati, V. Giannini, C. Castagneri, D. Regge, G. Balestra
Current research in radiology field is increasingly focusing on developing computer aided detection (CAD) systems able to support radiologists in the detection of suspicious regions, reducing oversight, errors and working time. Prostate cancer (PCa) is the most common cancer afflicting men in USA. Multiparametric Magnetic Resonance (mp-MR) imaging is recently emerging as a powerful tool for PCa diagnosis. The development of CAD systems for its automatic processing and elaboration is growing but they can be affected by the variation of the imaging characteristics of PCa depending on its aggressiveness and location. The aim of this study is to characterize the homogeneity of a large set of data derived from mp-MR images, in order to assess the effect on the performances of a CAD system for PCa detection. Firstly, 15 semiquantitative and quantitative features were extracted from malignant and normal region of interest in 60 patients, who underwent mp-MR exam before prostatectomy. Then, we used a clustering procedure based on a Self-Organizing Map (SOM) for grouping patients with similar characteristics from the features point of view. Finally, we evaluated the impact of this partition on the malignant voxel detection by means of a classifier based on a set of SOMs trained and tested using only those patient belonging to the same cluster. We compared these results with those obtained using a unique classifier for all patients. From our analysis it emerged that the image partition in homogeneous groups can effectively improve the final detection performances.
{"title":"Dataset homogeneity assessment for a prostate cancer CAD system","authors":"S. Rosati, V. Giannini, C. Castagneri, D. Regge, G. Balestra","doi":"10.1109/MeMeA.2016.7533734","DOIUrl":"https://doi.org/10.1109/MeMeA.2016.7533734","url":null,"abstract":"Current research in radiology field is increasingly focusing on developing computer aided detection (CAD) systems able to support radiologists in the detection of suspicious regions, reducing oversight, errors and working time. Prostate cancer (PCa) is the most common cancer afflicting men in USA. Multiparametric Magnetic Resonance (mp-MR) imaging is recently emerging as a powerful tool for PCa diagnosis. The development of CAD systems for its automatic processing and elaboration is growing but they can be affected by the variation of the imaging characteristics of PCa depending on its aggressiveness and location. The aim of this study is to characterize the homogeneity of a large set of data derived from mp-MR images, in order to assess the effect on the performances of a CAD system for PCa detection. Firstly, 15 semiquantitative and quantitative features were extracted from malignant and normal region of interest in 60 patients, who underwent mp-MR exam before prostatectomy. Then, we used a clustering procedure based on a Self-Organizing Map (SOM) for grouping patients with similar characteristics from the features point of view. Finally, we evaluated the impact of this partition on the malignant voxel detection by means of a classifier based on a set of SOMs trained and tested using only those patient belonging to the same cluster. We compared these results with those obtained using a unique classifier for all patients. From our analysis it emerged that the image partition in homogeneous groups can effectively improve the final detection performances.","PeriodicalId":221120,"journal":{"name":"2016 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"187 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114743215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-05-15DOI: 10.1109/MeMeA.2016.7533706
L. Battista, G. Summa
Patients who have acute respiratory failure and who have not responded to other treatment options can benefit from using a treatment, called Home Mechanical Ventilation. In order to allow the remote patient monitoring, in the last few years several tele-monitoring systems have been introduced, but most of them usually do not allow real-time services, are based on a wired connection, have their own proprietary serial communication protocol implemented and some ventilation parameters are not always measured. In order to reduce the above quoted drawbacks, in this work we report the development of a novel wireless remote monitoring system for long-term home-based ventilation therapy. The proposed system is based on the real-time monitoring of the main physical quantities involved during home-care ventilation and is developed in order to allow observation of different remote therapy units everywhere located in different places of a city, region or country. The developed remote patient monitoring system has been successfully tested by means of spirometric trials and, especially, by means of experimental tests carried out with pulmonary ventilators typically used to support sick patients.
{"title":"Preliminary evaluation of a wireless remote monitoring system for home mechanical ventilation","authors":"L. Battista, G. Summa","doi":"10.1109/MeMeA.2016.7533706","DOIUrl":"https://doi.org/10.1109/MeMeA.2016.7533706","url":null,"abstract":"Patients who have acute respiratory failure and who have not responded to other treatment options can benefit from using a treatment, called Home Mechanical Ventilation. In order to allow the remote patient monitoring, in the last few years several tele-monitoring systems have been introduced, but most of them usually do not allow real-time services, are based on a wired connection, have their own proprietary serial communication protocol implemented and some ventilation parameters are not always measured. In order to reduce the above quoted drawbacks, in this work we report the development of a novel wireless remote monitoring system for long-term home-based ventilation therapy. The proposed system is based on the real-time monitoring of the main physical quantities involved during home-care ventilation and is developed in order to allow observation of different remote therapy units everywhere located in different places of a city, region or country. The developed remote patient monitoring system has been successfully tested by means of spirometric trials and, especially, by means of experimental tests carried out with pulmonary ventilators typically used to support sick patients.","PeriodicalId":221120,"journal":{"name":"2016 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123677739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-05-15DOI: 10.1109/MeMeA.2016.7533726
E. Rizzuto, Enrica Urciuoli, B. Peruzzi, Z. Prete
Mechanical load is nowadays considered one of the factor mainly affecting bone tissue properties, both as architecture and functionality. Mechanotransduction is the capability of cells to translate mechanical stresses into biochemical signals, and several studies performed on mouse models demonstrated that also bone cells show a high responsiveness to mechanical stimuli. To date, bone cells mechanotransduction is mainly investigated in animal models, by the use of organ cultures or directly in vivo, and the actual strains induced by the external loads are measured through the use of micro strain gauges placed on the tibia mid-diaphysis. With the aim of proposing a new parameter to come along with the measurement of the actual strains, we exploited the capability of tibial global shortening to return useful information. We employed an experimental system based on a dual mode actuator/transducer with an adequate force range and a high length resolution to retrieve the small shortening of the bone specimens subjected to uniaxially load. Preliminary results showed that the tibia global shortening has a linear relationship with the increasing load, in the range of force usually used in these studies. In addition, the tibia global shortening showed the capability of gathering the changes occurring in the bone tissue mechanical properties when subjecting the specimens to loading signals of different frequencies. When tested with load signals of a frequency equal or higher than 1 Hz, in fact, the bone specimens showed a more rigid behavior. At 9 N of load, for example, the average value of tibia global shortening measured at 0.1 Hz is, on average, 18 % higher than when measured at all the other tested frequencies.
{"title":"The measurement of global shortening as a new parameter to evaluate bone specimen response to uniaxial loading: Length change measurement for bone tissue specimens","authors":"E. Rizzuto, Enrica Urciuoli, B. Peruzzi, Z. Prete","doi":"10.1109/MeMeA.2016.7533726","DOIUrl":"https://doi.org/10.1109/MeMeA.2016.7533726","url":null,"abstract":"Mechanical load is nowadays considered one of the factor mainly affecting bone tissue properties, both as architecture and functionality. Mechanotransduction is the capability of cells to translate mechanical stresses into biochemical signals, and several studies performed on mouse models demonstrated that also bone cells show a high responsiveness to mechanical stimuli. To date, bone cells mechanotransduction is mainly investigated in animal models, by the use of organ cultures or directly in vivo, and the actual strains induced by the external loads are measured through the use of micro strain gauges placed on the tibia mid-diaphysis. With the aim of proposing a new parameter to come along with the measurement of the actual strains, we exploited the capability of tibial global shortening to return useful information. We employed an experimental system based on a dual mode actuator/transducer with an adequate force range and a high length resolution to retrieve the small shortening of the bone specimens subjected to uniaxially load. Preliminary results showed that the tibia global shortening has a linear relationship with the increasing load, in the range of force usually used in these studies. In addition, the tibia global shortening showed the capability of gathering the changes occurring in the bone tissue mechanical properties when subjecting the specimens to loading signals of different frequencies. When tested with load signals of a frequency equal or higher than 1 Hz, in fact, the bone specimens showed a more rigid behavior. At 9 N of load, for example, the average value of tibia global shortening measured at 0.1 Hz is, on average, 18 % higher than when measured at all the other tested frequencies.","PeriodicalId":221120,"journal":{"name":"2016 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"102 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124722839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-05-15DOI: 10.1109/MeMeA.2016.7533744
Anja Jackowski, Marion Gebhard, A. Gräser
Within this work a novel head gesture based interface for hands-free control of a collaborative robot is developed and evaluated. Based on previous work, robot control is divided into several control groups for intuitive head motion based control. The switching commands to select and switch between these robot control groups are given by four gestures performed with head movements. The head movements were measured using a nine-axis inertial measurement unit. The control of a robot with the novel interface was evaluated objectively as well as subjectively. The objective evaluation contains the measurement of time needed for the given control task and the number of trials for switching between the different groups of robot control. The subjective evaluation was carried out with a questionnaire. All subjects were able to perform the given task of controlling a robot arm with the head gesture based interface.
{"title":"A novel head gesture based interface for hands-free control of a robot","authors":"Anja Jackowski, Marion Gebhard, A. Gräser","doi":"10.1109/MeMeA.2016.7533744","DOIUrl":"https://doi.org/10.1109/MeMeA.2016.7533744","url":null,"abstract":"Within this work a novel head gesture based interface for hands-free control of a collaborative robot is developed and evaluated. Based on previous work, robot control is divided into several control groups for intuitive head motion based control. The switching commands to select and switch between these robot control groups are given by four gestures performed with head movements. The head movements were measured using a nine-axis inertial measurement unit. The control of a robot with the novel interface was evaluated objectively as well as subjectively. The objective evaluation contains the measurement of time needed for the given control task and the number of trials for switching between the different groups of robot control. The subjective evaluation was carried out with a questionnaire. All subjects were able to perform the given task of controlling a robot arm with the head gesture based interface.","PeriodicalId":221120,"journal":{"name":"2016 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122164938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-05-15DOI: 10.1109/MeMeA.2016.7533811
Udaya Wijenayake, Soon-Yong Park
Human respiration induces considerable external and internal motion in the thoracic and abdominal regions. Tracking and modeling of this motion is an important task for accurate treatment planning and dose calculation during external beam radiotherapy. Inaccurate motion tracking can cause severe issues such as errors in target/normal tissue delineation and increment in the volume of healthy tissues exposed to high doses. Different methods have been introduced to model the respiratory motion, but most of them use wearable markers or surgical node implanting techniques, which are inconvenient to patients. In this paper, we experiment the feasibility of using an RGB-D camera along with Principal Component Analysis (PCA) to track and model the subject-specific external respiratory motion. Marker-based depth frame registration technique is also introduced to limit the measuring area into an anatomically consistent region during the treatment. We evaluate the accuracy of the proposed method using a Spirometer and a laser line scanner.
{"title":"PCA based analysis of external respiratory motion using an RGB-D camera","authors":"Udaya Wijenayake, Soon-Yong Park","doi":"10.1109/MeMeA.2016.7533811","DOIUrl":"https://doi.org/10.1109/MeMeA.2016.7533811","url":null,"abstract":"Human respiration induces considerable external and internal motion in the thoracic and abdominal regions. Tracking and modeling of this motion is an important task for accurate treatment planning and dose calculation during external beam radiotherapy. Inaccurate motion tracking can cause severe issues such as errors in target/normal tissue delineation and increment in the volume of healthy tissues exposed to high doses. Different methods have been introduced to model the respiratory motion, but most of them use wearable markers or surgical node implanting techniques, which are inconvenient to patients. In this paper, we experiment the feasibility of using an RGB-D camera along with Principal Component Analysis (PCA) to track and model the subject-specific external respiratory motion. Marker-based depth frame registration technique is also introduced to limit the measuring area into an anatomically consistent region during the treatment. We evaluate the accuracy of the proposed method using a Spirometer and a laser line scanner.","PeriodicalId":221120,"journal":{"name":"2016 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"188 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121850019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-05-15DOI: 10.1109/MeMeA.2016.7533790
C. Jaffelin, E. Cinotti, J. Perrot, B. Labeille, F. Cambazard, L. Tognetti, P. Rubegni, J. Pittet
Introduction: iloprost is a recommended treatment for several vascular diseases such as severe Raynaud's syndrome and digital ulcers in Systemic Sclerosis (SS). In vivo reflectance confocal microscopy (RCM) is a non-invasive imaging tool that can evaluate cutaneous microcirculation. The goal of this study was to observe, in real time, the effect of iloprost on cutaneous microcirculation by using RCM. Material and method: Five patients with microvascular diseases that needed iloprost were included. Administration speed started at 0.5 ng/kg/min until the maximum tolerated dosage. Recordings of capillary flow were done using RCM before treatment and at each change in the drug dosage. Results: The blood flow of the five patients demonstrated a significant increase from the dosage of 0.5 ng/kg/min. This significant variation did not exist at higher dosage. Discussion: This study suggests a precocious effect of iloprost in increasing the cutaneous vascular flow; this effect was not enhanced at higher drug dosage. Monitoring cutaneous capillary flow by in vivo RCM could then be of interest in optimizing iloprost dosage. This procedure will likely reduce the side effects of iloprost that are dose-dependent.
{"title":"Practical interest of in vivo reflectance confocal microscopy quantification of cutaneous vascular flow during iloprost treatment","authors":"C. Jaffelin, E. Cinotti, J. Perrot, B. Labeille, F. Cambazard, L. Tognetti, P. Rubegni, J. Pittet","doi":"10.1109/MeMeA.2016.7533790","DOIUrl":"https://doi.org/10.1109/MeMeA.2016.7533790","url":null,"abstract":"Introduction: iloprost is a recommended treatment for several vascular diseases such as severe Raynaud's syndrome and digital ulcers in Systemic Sclerosis (SS). In vivo reflectance confocal microscopy (RCM) is a non-invasive imaging tool that can evaluate cutaneous microcirculation. The goal of this study was to observe, in real time, the effect of iloprost on cutaneous microcirculation by using RCM. Material and method: Five patients with microvascular diseases that needed iloprost were included. Administration speed started at 0.5 ng/kg/min until the maximum tolerated dosage. Recordings of capillary flow were done using RCM before treatment and at each change in the drug dosage. Results: The blood flow of the five patients demonstrated a significant increase from the dosage of 0.5 ng/kg/min. This significant variation did not exist at higher dosage. Discussion: This study suggests a precocious effect of iloprost in increasing the cutaneous vascular flow; this effect was not enhanced at higher drug dosage. Monitoring cutaneous capillary flow by in vivo RCM could then be of interest in optimizing iloprost dosage. This procedure will likely reduce the side effects of iloprost that are dose-dependent.","PeriodicalId":221120,"journal":{"name":"2016 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127520815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-05-15DOI: 10.1109/MeMeA.2016.7533735
Mauro Cerquitella, P. Saccomandi, E. Schena, S. Silvestri, S. Scarlata, R. Giua
The pleural fluid is a viscous substance between the two pleural layers of the lungs, important in the respiratory mechanics. A pleural effusion (PE) is an excess of pleural fluid in the pleural cavity, caused by several pathologies (e.g., pulmonary embolism, cancer, and infections). Because of its incidence, PE identification and quantification are important to lead the clinician in the selection of the optimal therapeutic strategy. PE volume can be estimated by invasive (quantitative) and non-invasive (qualitative) approaches. Invasive methods provide accurate measurement of PE volume and utilize Computed Tomography (CT) imaging and thoracentesis. Non-invasive methods are based on Ultrasound (US) imaging and are able to identify the PE, but do not quantify its volume. Aiming to spare the patients from risks due to X-ray exposure and invasiveness of thoracentesis, a non-invasive approach for the estimation of PE is coveted. The aim of this study is the feasibility assessment of a simple and affordable model for the quantification of PE through US images. Two US scans are performed to measure: the height of PE column (hPEUS) and the area of the effusion (aPEUS) in correspondence of half hPEUS. The proposed model estimates the PE volume (PEVUS) by multiplying hPEUS and aPEUS, based on cylindrical approximation. PEVUS are compared with PE volumes estimated by CT scans (PEVct), achieved within 24 h from the US exam. The model was successfully tested on 7 patients for PE volumes ranging from 70 mL to 550 mL. The good agreement between PEVus and PEVct volumes is witnessed by the slope of the best fitting line (0.988) and the high correlation coefficient (R=0.99). The two measurements are also compared by Bland-Altman plot, which provides a mean of difference of 1.7 mL and limits of agreement of -32.5 mL and +36.0 mL. The findings of this work show that the proposed model can be a valid tool for the estimation of PE volume by means of US exam. An important advantage of this model is the possibility to quantify PE by the measurements of only two parameters. This approach is not time consuming, hence it can be easily implemented in clinical routine.
{"title":"Ultrasound estimation of pleural effusion in geriatric patients","authors":"Mauro Cerquitella, P. Saccomandi, E. Schena, S. Silvestri, S. Scarlata, R. Giua","doi":"10.1109/MeMeA.2016.7533735","DOIUrl":"https://doi.org/10.1109/MeMeA.2016.7533735","url":null,"abstract":"The pleural fluid is a viscous substance between the two pleural layers of the lungs, important in the respiratory mechanics. A pleural effusion (PE) is an excess of pleural fluid in the pleural cavity, caused by several pathologies (e.g., pulmonary embolism, cancer, and infections). Because of its incidence, PE identification and quantification are important to lead the clinician in the selection of the optimal therapeutic strategy. PE volume can be estimated by invasive (quantitative) and non-invasive (qualitative) approaches. Invasive methods provide accurate measurement of PE volume and utilize Computed Tomography (CT) imaging and thoracentesis. Non-invasive methods are based on Ultrasound (US) imaging and are able to identify the PE, but do not quantify its volume. Aiming to spare the patients from risks due to X-ray exposure and invasiveness of thoracentesis, a non-invasive approach for the estimation of PE is coveted. The aim of this study is the feasibility assessment of a simple and affordable model for the quantification of PE through US images. Two US scans are performed to measure: the height of PE column (hPEUS) and the area of the effusion (aPEUS) in correspondence of half hPEUS. The proposed model estimates the PE volume (PEVUS) by multiplying hPEUS and aPEUS, based on cylindrical approximation. PEVUS are compared with PE volumes estimated by CT scans (PEVct), achieved within 24 h from the US exam. The model was successfully tested on 7 patients for PE volumes ranging from 70 mL to 550 mL. The good agreement between PEVus and PEVct volumes is witnessed by the slope of the best fitting line (0.988) and the high correlation coefficient (R=0.99). The two measurements are also compared by Bland-Altman plot, which provides a mean of difference of 1.7 mL and limits of agreement of -32.5 mL and +36.0 mL. The findings of this work show that the proposed model can be a valid tool for the estimation of PE volume by means of US exam. An important advantage of this model is the possibility to quantify PE by the measurements of only two parameters. This approach is not time consuming, hence it can be easily implemented in clinical routine.","PeriodicalId":221120,"journal":{"name":"2016 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"3019 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127461565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-05-15DOI: 10.1109/MeMeA.2016.7533698
Chiara Losquadro, P. Saccomandi, C. Massaroni, E. Schena
During invasive artificial ventilation is crucial to heat and to humidify gases delivered to patients. Heated Wire Humidifiers (HWHs) are largely used to perform this task. Their performances are strongly influenced by ventilatory settings (e.g., Minute Volume-MV- and respiratory frequency-f-), and environmental conditions. An important concern in case of over-humidification is the formation of water condensation within the breathing circuit, which increases the risk for pulmonary infection and the occlusion of endotracheal tube. Several studies assessed the water condensation by qualitative scales. This work aims to estimate the mass of condensed vapor within the breathing circuit at different MV and f, covering all the conditions used during adult ventilation. Results show that the condensed vapor increases with both MV and f. Moreover, preliminary experiments show that the condensation decreases with room temperature. The substantial amount of condensation confirms the weaknesses of the control strategy mostly implemented on commercial HWHs. These data can be helpful to figure out the impact of ventilatory settings on HWHs performances and to find out novel solutions to improve them.
{"title":"Performances of heated wire humidifiers during adult mechanical ventilation: Estimation of the amount of condensation","authors":"Chiara Losquadro, P. Saccomandi, C. Massaroni, E. Schena","doi":"10.1109/MeMeA.2016.7533698","DOIUrl":"https://doi.org/10.1109/MeMeA.2016.7533698","url":null,"abstract":"During invasive artificial ventilation is crucial to heat and to humidify gases delivered to patients. Heated Wire Humidifiers (HWHs) are largely used to perform this task. Their performances are strongly influenced by ventilatory settings (e.g., Minute Volume-MV- and respiratory frequency-f-), and environmental conditions. An important concern in case of over-humidification is the formation of water condensation within the breathing circuit, which increases the risk for pulmonary infection and the occlusion of endotracheal tube. Several studies assessed the water condensation by qualitative scales. This work aims to estimate the mass of condensed vapor within the breathing circuit at different MV and f, covering all the conditions used during adult ventilation. Results show that the condensed vapor increases with both MV and f. Moreover, preliminary experiments show that the condensation decreases with room temperature. The substantial amount of condensation confirms the weaknesses of the control strategy mostly implemented on commercial HWHs. These data can be helpful to figure out the impact of ventilatory settings on HWHs performances and to find out novel solutions to improve them.","PeriodicalId":221120,"journal":{"name":"2016 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125307793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-05-15DOI: 10.1109/MeMeA.2016.7533795
S. Martinez, O. Kuzmicheva, A. Gräser
This paper presents a study on overground non-pathological gait, focusing on hip and knee joint trajectories in sagittal plane. The objects of study are some characteristic points of the joint curves (including the extrema) and their relation to gait parameters, namely normalized walking speed, cadence and normalized step length. The main objective is to predict the spatio-temporal values of these points depending on given gait parameters. To this end, a study with 18 healthy subjects was conducted, where they were asked to walk as comfortable as possible whilst following different tasks, namely walking with desired and given cadence, step length and speed. The data was processed and fed to artificial neural networks to obtain an algorithm able to predict the characteristic points. Specifics of the study protocol and data processing are presented, as well as the prediction results.
{"title":"Prediction of characteristic points of hip and knee joint trajectories during overground walking using IMUs and Artificial Neural Networks","authors":"S. Martinez, O. Kuzmicheva, A. Gräser","doi":"10.1109/MeMeA.2016.7533795","DOIUrl":"https://doi.org/10.1109/MeMeA.2016.7533795","url":null,"abstract":"This paper presents a study on overground non-pathological gait, focusing on hip and knee joint trajectories in sagittal plane. The objects of study are some characteristic points of the joint curves (including the extrema) and their relation to gait parameters, namely normalized walking speed, cadence and normalized step length. The main objective is to predict the spatio-temporal values of these points depending on given gait parameters. To this end, a study with 18 healthy subjects was conducted, where they were asked to walk as comfortable as possible whilst following different tasks, namely walking with desired and given cadence, step length and speed. The data was processed and fed to artificial neural networks to obtain an algorithm able to predict the characteristic points. Specifics of the study protocol and data processing are presented, as well as the prediction results.","PeriodicalId":221120,"journal":{"name":"2016 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"177 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133864195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：