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2016 IEEE International Symposium on Medical Measurements and Applications (MeMeA)最新文献

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Dataset homogeneity assessment for a prostate cancer CAD system 前列腺癌CAD系统的数据集同质性评估
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533734
S. Rosati, V. Giannini, C. Castagneri, D. Regge, G. Balestra
Current research in radiology field is increasingly focusing on developing computer aided detection (CAD) systems able to support radiologists in the detection of suspicious regions, reducing oversight, errors and working time. Prostate cancer (PCa) is the most common cancer afflicting men in USA. Multiparametric Magnetic Resonance (mp-MR) imaging is recently emerging as a powerful tool for PCa diagnosis. The development of CAD systems for its automatic processing and elaboration is growing but they can be affected by the variation of the imaging characteristics of PCa depending on its aggressiveness and location. The aim of this study is to characterize the homogeneity of a large set of data derived from mp-MR images, in order to assess the effect on the performances of a CAD system for PCa detection. Firstly, 15 semiquantitative and quantitative features were extracted from malignant and normal region of interest in 60 patients, who underwent mp-MR exam before prostatectomy. Then, we used a clustering procedure based on a Self-Organizing Map (SOM) for grouping patients with similar characteristics from the features point of view. Finally, we evaluated the impact of this partition on the malignant voxel detection by means of a classifier based on a set of SOMs trained and tested using only those patient belonging to the same cluster. We compared these results with those obtained using a unique classifier for all patients. From our analysis it emerged that the image partition in homogeneous groups can effectively improve the final detection performances.
当前放射学领域的研究越来越关注于开发能够支持放射科医生检测可疑区域的计算机辅助检测(CAD)系统,以减少疏忽、错误和工作时间。前列腺癌(PCa)是美国男性最常见的癌症。多参数磁共振(mp-MR)成像最近成为前列腺癌诊断的有力工具。用于其自动处理和细化的CAD系统的发展正在增长,但它们可能受到前列腺癌的成像特征变化的影响,这取决于其侵袭性和位置。本研究的目的是表征来自mp-MR图像的大量数据的同质性,以评估对PCa检测的CAD系统性能的影响。首先,对60例前列腺切除术前行mp-MR检查的患者,从感兴趣的恶性和正常区域提取15个半定量和定量特征。然后,我们使用基于自组织地图(SOM)的聚类程序,从特征的角度对具有相似特征的患者进行分组。最后,我们评估了这种划分对恶性体素检测的影响,该分类器基于一组仅使用属于同一聚类的患者训练和测试的SOMs。我们将这些结果与所有患者使用独特分类器获得的结果进行比较。分析表明,对图像进行同质分组可以有效地提高最终的检测性能。
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引用次数: 3
Recognition of vertebral compression fractures in magnetic resonance images using statistics of height and width 利用高度和宽度统计的磁共振图像识别椎体压缩性骨折
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533731
L. Frighetto-Pereira, G. A. Metzner, P. M. A. Marques, M. Nogueira-Barbosa, Foad Oloumi, R. Rangayyan
Vertebral compression fractures (VCFs) present as partial collapses of vertebral bodies and may occur secondary to osteoporosis bone fragility and to metastatic cancer infiltration. The correct diagnosis of nontraumatic VCFs is therefore, fundamental for correct treatment. We aimed to classify VCFs using T1-weighted magnetic resonance images (MRI) of the lumbar spine acquired in the sagittal plane. Our study group comprised 63 patients (38 women and 25 men). From these patients 102 lumbar VCFs (53 benign and 49 malignant) and 89 normal vertebral bodies were manually segmented. The principal axis of each vertebral body region of interest was identified using moments. Statistical features of height and width measured perpendicular and parallel to the principal axis were computed. The k-nearest-neighbor method, a neural network with radial basis functions, and the naïve Bayes classifier were used with feature selection for classification. Areas under the receiver operating characteristic curve of 0.96 in the recognition of VCFs as compared with normal vertebral bodies and 0.73 for the classification of benign versus malignant VCFs were obtained. The proposed methods are promising for the recognition of VCFs, but additional features are needed to improve the classification of benign versus malignant VCFs.
椎体压缩性骨折(vcf)表现为椎体的部分塌陷,可能继发于骨质疏松、骨脆性和转移性癌症浸润。因此,正确诊断非创伤性vcf是正确治疗的基础。我们的目的是利用腰椎矢状面t1加权磁共振图像(MRI)对vcf进行分类。我们的研究组包括63例患者(38例女性和25例男性)。对102例腰椎vcf(53例良性,49例恶性)和89例正常椎体进行手工分割。利用矩确定每个感兴趣的椎体区域的主轴。计算了垂直于和平行于主轴测量的高度和宽度的统计特征。采用k-近邻法、径向基神经网络和naïve贝叶斯分类器结合特征选择进行分类。与正常椎体相比,识别vcf的受者工作特征曲线下面积为0.96,良性与恶性vcf的分类面积为0.73。所提出的方法对于vcf的识别是有希望的,但需要额外的特征来改进良性和恶性vcf的分类。
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引用次数: 3
Prediction of characteristic points of hip and knee joint trajectories during overground walking using IMUs and Artificial Neural Networks 利用imu和人工神经网络预测地上行走时髋关节和膝关节轨迹特征点
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533795
S. Martinez, O. Kuzmicheva, A. Gräser
This paper presents a study on overground non-pathological gait, focusing on hip and knee joint trajectories in sagittal plane. The objects of study are some characteristic points of the joint curves (including the extrema) and their relation to gait parameters, namely normalized walking speed, cadence and normalized step length. The main objective is to predict the spatio-temporal values of these points depending on given gait parameters. To this end, a study with 18 healthy subjects was conducted, where they were asked to walk as comfortable as possible whilst following different tasks, namely walking with desired and given cadence, step length and speed. The data was processed and fed to artificial neural networks to obtain an algorithm able to predict the characteristic points. Specifics of the study protocol and data processing are presented, as well as the prediction results.
本文对地面非病理性步态进行了研究,重点研究了髋关节和膝关节在矢状面上的运动轨迹。研究对象是关节曲线的一些特征点(包括极值点)及其与归一化步行速度、步速、步长等步态参数的关系。主要目标是根据给定的步态参数预测这些点的时空值。为此,研究人员对18名健康受试者进行了一项研究,要求他们在完成不同的任务时尽可能舒适地行走,即以期望的和给定的节奏、步长和速度行走。对数据进行处理,并将其输入到人工神经网络中,得到一种能够预测特征点的算法。详细介绍了研究方案和数据处理,以及预测结果。
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引用次数: 4
A reflectance photoplethysmography based device to detect circulatory disruptions 一种基于反射光容积脉搏波的检测循环中断的装置
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533789
S. Karthik, M. Sivaprakasam, J. Joseph, S. Preejith
We study the potential of reflectance photoplethysmography (PPG) in monitoring free flaps for arterial and venous thrombosis in post-surgical scenarios. Circulatory disruptions due to thrombosis were simulated using limb ischemia method on 30 volunteers. Arterial and venous occlusions were conducted in this study. The variation in blood flow in the region of interest was captured by a custom built sensor and data acquisition system using dual wavelength reflectance photoplethysmography. The main chromophores in blood, oxygenated and reduced hemoglobin, showed good variation to visible - near infrared wavelengths with concentration and volume changes. Sensitivity of the prototype device in detecting arterial and venous circulation disruptions was evaluated at various different threshold levels of signal parameters. The device showed strong capability to accurately detect circulatory disruptions and has potential in post-surgical monitoring of free flaps.
我们研究了反射光体积脉搏波(PPG)在监测游离皮瓣术后动脉和静脉血栓形成方面的潜力。采用肢体缺血法模拟30例志愿者血栓形成引起的循环中断。本研究进行了动脉和静脉闭塞。一个定制的传感器和数据采集系统使用双波长反射光体积脉搏描记仪捕获感兴趣区域的血流变化。血中主要的发色团,氧合血红蛋白和还原血红蛋白,随浓度和体积的变化在可见-近红外波段表现出良好的变化。在各种不同的信号参数阈值水平下,评估了原型装置检测动脉和静脉循环中断的灵敏度。该装置显示出准确检测循环中断的强大能力,并在手术后监测自由皮瓣方面具有潜力。
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引用次数: 1
Non-invasive measurement of hemoglobin concentration using magnetic plethysmo gram 利用磁胸腺图无创测量血红蛋白浓度
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533776
J. Bai, S. Mohanasankar, V. Kumar
A method for determining the concentration of hemoglobin in arterial blood, non invasively, is explored in this paper. A permanent magnet is placed just above the radial artery of a person whose hemoglobin concentration is to be ascertained. The flux produced by the permanent magnet (that links with the blood flow in the radial artery) is sensed to obtain a signal called magnetic plethysmogram (MPG). In this paper, an analytical model for a magnetic plethysmogram is derived. Using the proposed analytical model, a method of estimation of the concentration of hemoglobin in arterial blood is derived. The proposed method is then validated through a limited clinical study. The results of the clinical study establish the viability of measuring hemoglobin concentration, noninvasively, using magnetic plethysmogram.
本文探讨了一种无创测定动脉血中血红蛋白浓度的方法。将永磁体放置在待测定血红蛋白浓度的人的桡动脉上方。永磁体产生的磁通量(与桡动脉的血流相连)被感知,从而获得一种称为磁容积图(MPG)的信号。本文推导了磁容积谱的解析模型。利用所提出的分析模型,导出了一种估算动脉血中血红蛋白浓度的方法。然后通过有限的临床研究验证了所提出的方法。临床研究的结果建立了可行性测量血红蛋白浓度,无创,使用磁容积描记图。
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引用次数: 4
Technical challenges using magneto-inertial sensors for gait analysis 使用磁惯性传感器进行步态分析的技术挑战
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533746
L. Gastaldi, V. Rosso, V. Gabola, V. Agostini, M. M. L. Frutos, M. Knaflitz, Ryo Takeda, S. Tadano
Magneto-Inertial Measurement Units (MIMUs) are gathering an increasing consensus in human motion analysis. However, applications such as clinical gait analysis require reliable, repeatable and accurate measurements of gait parameters up to a level that it is not easily achievable with MIMUs. We pointed out some specific technical challenges that we encountered in the use of the MIMUs-based H-gait system, pertaining to 1) calibration procedure and 2) high dispersion of ankle joint kinematic curves. We described how we solved these issues: 1) shifting from a manual to a semi-automatic calibration procedure and 2) obtaining an optimal MIMUs positioning on the foot. Joint kinematic results were validated against those acquired with a standard electromechanical system (STEP32).
磁惯性测量单元(mimu)在人体运动分析中获得越来越多的共识。然而,临床步态分析等应用需要可靠,可重复和准确的步态参数测量,达到mimu不容易实现的水平。我们指出了在使用基于mimi的h -步态系统时遇到的一些具体的技术挑战,涉及到1)校准程序和2)踝关节运动曲线的高度分散。我们描述了如何解决这些问题:1)从手动转向半自动校准程序;2)在脚上获得最佳的mimu定位。关节运动学结果与标准机电系统(STEP32)获得的结果进行了验证。
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引用次数: 6
Multidimensional assessment of pain in women with endometriosis: Preliminary results of the experience in Cagliari 子宫内膜异位症妇女疼痛的多维评估:卡利亚里经验的初步结果
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533773
I. Melis, M. P. Penna, Marta Murru, A. Pontis, M. Agus, S. Angioni
Endometriosis is a chronic disease that affects women of reproductive age. Chronic pelvic pain, dysmenorrhea, and dyspareunia are its main symptoms; pain alters the quality of life of the patient and affects her health. Since pain is a highly subjective experience, the purpose of this study is to assess the sensory component of pain perception in endometriosis, alongside the affective-emotional and cognitive aspects. These aspects were linked with anamnestic data, anxiety, and depression. We administered appropriate instruments in order to assess these dimensions (QUID - Italian Pain Questionnaire, Biberoglu's Scale, and the HADS Scale), and we evaluated their relationships.
子宫内膜异位症是一种影响育龄妇女的慢性疾病。慢性盆腔疼痛、痛经、性交困难是其主要症状;疼痛会改变患者的生活质量,影响其健康。由于疼痛是一种高度主观的体验,本研究的目的是评估子宫内膜异位症疼痛感知的感官成分,以及情感-情绪和认知方面。这些方面与失忆数据、焦虑和抑郁有关。我们使用适当的工具来评估这些维度(QUID -意大利疼痛问卷,Biberoglu量表和HADS量表),并评估它们之间的关系。
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引用次数: 3
Swimming symmetry assessment via multiple inertial measurements 通过多次惯性测量评估游泳对称性
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533765
M. Parvis, S. Grassini, E. Angelini, Pietro Scattareggia
Spinal diseases and spine curvature disorders often need swimming rehabilitation to recover as much as function as possible. During swimming sessions the trainer is able of discriminating by sight large movement problems connected to the back pain, but an automatic intelligent system capable to assess the presence of movement problems could help the swimmer doing therapy by him/herself. This paper describes a possible easy-to-use solution, which is based on four small inertial systems to be installed on wrists and ankles in order to follow the movements of legs and arms. The inertial systems are composed of a commercial miniaturized Inertial Measurement Unit and by a Teensyduino board, which is able to store up to ten thousand inertial samples enabling recording the swimming for about four minutes. Angular velocity and acceleration recorded by the inertial systems are then transferred to a computer via an USB cable and processed to obtain an indication of the swimming asymmetry. The paper describes the design and realization of the acquisition units and the first results obtained by some patients during their therapy.
脊柱疾病和脊柱弯曲障碍往往需要游泳康复,以恢复尽可能多的功能。在游泳训练期间,训练者能够通过视觉辨别与背部疼痛相关的大的运动问题,但是一个能够评估运动问题存在的自动智能系统可以帮助游泳者自己进行治疗。本文描述了一种可能的易于使用的解决方案,该解决方案基于四个安装在手腕和脚踝上的小型惯性系统,以便跟随腿和手臂的运动。惯性测量系统由一个商业小型化的惯性测量单元和一个能够存储多达一万个惯性样本的Teensyduino板组成,可以记录大约四分钟的游泳过程。由惯性系统记录的角速度和加速度然后通过USB电缆传输到计算机并进行处理以获得游泳不对称的指示。本文介绍了获取单元的设计与实现,以及一些患者在治疗过程中获得的第一效果。
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引用次数: 12
Season and anatomic site effect on skin color and xerosis quantified using an ultra-high definition videodermoscope 季节和解剖部位对皮肤颜色和干燥症的影响采用超高清视频皮肤镜量化
Pub Date : 2016-05-15 DOI: 10.1109/MEMEA.2016.7533791
E. Cinotti, J. Perrot, B. Labeille, F. Cambazard, R. Vie, A. Delalleau, L. Tognetti, P. Rubegni
Videodermoscopy has been used for the diagnosis of skin cancers and could be of potential interest to assess the quality of the skin in the cosmetic field, especially for the evaluation of skin color and xerosis. We evaluated whether it is possible to observe a variation of skin erythema, yellowness, pigmentation, color variance and xerosis induced by the season effect and the evaluated body site by using a new ultra-high definition videodermoscope. This videodermoscope provides images independent from the external lightening and reproducible. Videodermoscopy images were acquired at three body sites (photo-exposed forearm and face and photo-protected arm) of 149 elderly healthy volunteers. 79 subjects were evaluated in March and 70 subjects were evaluated in November. We found a difference in erythema, pigmentation, xerosis and yellowness in the two groups of subjects evaluated before and after the summer. As expected, erythema, pigmentation and xerosis increased and yellowness decreased after the summer. Some differences of these parameters were found in the three body sites independently from sun exposure. Videodermoscopy can provide quantitative data about both skin color and xerosis and in the future it could be used to evaluate different cosmetics and aesthetical procedures.
视频皮肤镜检查已被用于皮肤癌的诊断,并可能在化妆品领域对评估皮肤质量有潜在的兴趣,特别是对皮肤颜色和干燥的评估。我们评估了是否有可能观察到季节效应和评估身体部位引起的皮肤红斑、黄度、色素沉着、颜色变化和干燥的变化。这种视频显微镜提供的图像独立于外部照明和再现。对149名健康老年志愿者的三个身体部位(暴露在照片下的前臂、面部和保护在照片下的手臂)进行皮肤镜录像检查。3月评估79名受试者,11月评估70名受试者。我们发现在夏季前后评估的两组受试者在红斑、色素沉着、干燥和发黄方面存在差异。正如预期的那样,夏季过后,红斑、色素沉着和干燥症增加,黄度减少。在三个身体部位发现这些参数的一些差异与阳光照射无关。视频皮肤镜可以提供皮肤颜色和干燥症的定量数据,将来可以用于评估不同的化妆品和美容程序。
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引用次数: 3
A study on electrode placement in EOG systems for medical applications 医用EOG系统中电极放置的研究
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533703
Alberto López, Francisco Javier Ferrero Martín, M. Valledor, Juan Carlos Campo Rodríguez, O. Postolache
The eye acts as a dipole between the cornea (positive potential) and the retina (negative potential) which causes an electric field around the eyeball. Therefore, when humans make saccadic eye movements, they generate signals relative to this potential called electrooculography (EOG) signals. These signals can be measured by placing electrodes near the eye. Different electrode configurations can be employed to acquire the EOG signals. The properties of these signals change depending on the number and placement of the electrodes. Therefore, this paper presents a comparative study of electrode placement used to measure EOG signals. In order to support this study a low-cost signal acquisition hardware was developed. It enables the comparison of different electrode placements while showing the particularities of each one. The aim of this study is to analyse which electrode configuration could be best for medical applications.
眼睛在角膜(正电位)和视网膜(负电位)之间充当偶极子,在眼球周围产生电场。因此,当人类进行跳眼运动时,他们会产生与这种电位相关的信号,称为眼电(EOG)信号。这些信号可以通过在眼睛附近放置电极来测量。可以采用不同的电极配置来获取eeg信号。这些信号的性质根据电极的数量和位置而变化。因此,本文提出了一种用于测量eeg信号的电极放置的比较研究。为了支持这项研究,开发了一种低成本的信号采集硬件。它可以比较不同的电极位置,同时显示每个电极的特殊性。这项研究的目的是分析哪种电极配置最适合医疗应用。
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引用次数: 30
期刊
2016 IEEE International Symposium on Medical Measurements and Applications (MeMeA)
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