Vitae-revista De La Facultad De Quimica Farmaceutica最新文献

{"title":"EVALUATION OF PHARMACOTHERAPY USED ON GERIATRIC POPULATION IN AN INSTITUTION OF SPECIAL REGIME WITH THE SCREENING TOOL OF OLDER PERSONS’ POTENTIALLY INAPPROPRIATE PRESCRIPTIONS (STOPP) CRITERIA","authors":"E. AnaMaríaHerrera, G. JoséJuliánLópez","doi":"10.17533/UDEA.VITAE.V23N1A08","DOIUrl":"https://doi.org/10.17533/UDEA.VITAE.V23N1A08","url":null,"abstract":"Background: Geriatric patients represent a major challenge for appropriate prescription because they have significant changes in vital areas, multiple comorbidities among other things that encourage their fragility. In light of current evidence, the number of prescription errors increases with age and with the number of drugs USED, showing that people over 65 is at greater risk of medical error when more than 8 drugs are consumed. Objectives: To identify and describe the inappropriate medicines in elderly people in order to propose an institutional prescription guide based on the results of the application of the Screening Tool of Older Persons’ Potentially Inappropriate Prescriptions (STOPP) assessment methodology. Methods: A cross-section observational study with a retrospective collection of information was carried out in order to identify the frequency of inappropriate prescriptions in 300 elderly patients that were over 65 years, with a consumption of more than 5 medications and applying the STOPP criteria. The study was made in a special regime medical institution, reviewing medical records and considering variables such as number of medications, indications, dosage, therapeutic duplication, interactions and contraindications, among others. Results: The principal diagnosis was hipertension (47%) followed by diabetes mellitus (10%) and other hypothyroidisms (4%).After applying the STOPP criteria to each of the medical records, it was found that 50.7% (152) of the studied population had at least one inappropriate prescription distributed as follows: 2 prescriptions had 4 STOPP criteria, 7 prescriptions had 3 STOPP criteria, 28 had 2 STOPP criteria and 115 had 1 STOPP criteria. Conclusions: It was found that half of the prescriptions have at least one inadequate prescribed criteria, being the most important the inappropriate use of not indicated drugs or without an indication. Finally, guidelines for the rational use of drugs in the elderly with every detail of this institution are proposed.","PeriodicalId":23515,"journal":{"name":"Vitae-revista De La Facultad De Quimica Farmaceutica","volume":"31 1","pages":"78-84"},"PeriodicalIF":0.0,"publicationDate":"2016-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83697378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DEVELOPMENT AND APPLICATION OF EDIBLE COATINGS IN MINIMALLY PROCESSED FRUIT","authors":"Ricardo D. Andrade Pizarro, C. Cervera, D. L. Rhenals","doi":"10.17533/UDEA.VITAE.V23N1A01","DOIUrl":"https://doi.org/10.17533/UDEA.VITAE.V23N1A01","url":null,"abstract":"The consumer’s interest to purchase safe, nutritious, minimally processed, and healthy food has increased consumption of various fruits and vegetables. Generally, the quality of fruits depends on nutritional, microbiological and organoleptic properties, all of which are exposed to dynamic changes during harvesting, storage, and marketing. These changes are mainly due to the interactions between the fruits and its surroundings or migration among different inner components, which can result in loss of moisture and some volatile compounds.","PeriodicalId":23515,"journal":{"name":"Vitae-revista De La Facultad De Quimica Farmaceutica","volume":"21 1","pages":"9-10"},"PeriodicalIF":0.0,"publicationDate":"2016-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76155716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SCREENING OF MARINE BACTERIAL STRAINS AS SOURCE OF QUORUM SENSING INHIBITORS (QSI): FIRST CHEMICAL STUDY OF Oceanobacillus profundus (RKHC-62B)","authors":"D. Martínez-Matamoros, Melisa Laiton Fonseca, C. Duque, Freddy A. Ramos, L. Castellanos","doi":"10.17533/UDEA.VITAE.V23N1A04","DOIUrl":"https://doi.org/10.17533/UDEA.VITAE.V23N1A04","url":null,"abstract":"Antecedentes: Los productos naturales aislados de microorganismos marinos han demostrado tener un amplio rango de actividades biologicas incluyendo inhibidores de quorum sensing. Objetivos: Estudiamos quince cepas bacterianas del phylum Firmicutes aisladas del coral blando Antillogorgia elisabethae que fueron evaluadas como una nueva fuente sostenible de compuestos inhibidores de quorum sensing (IQS). Metodos: Se prepararon cultivos en cuatro medios diferentes y extraidos usando una resina no ionica. Todos los extractos fueron probados con el fin de establecer su actividad inhibitoria de quorum sensing (IQS) usando Chromobacterium violaceum ATCC 31532 como biosensor. Los extractos activos fueron fraccionados mediante cartuchos RP-18. Cada fraccion fue evaluada mediante bioensayo y analizada por HPLC. Resultados: Las fracciones metanolicas de Jeotgalicoccus halophilus y Oceanobacillus profundus fueron las mas activas, lo cual sugiere que los compuestos no polares pueden ser los responsables de esta actividad. Conclusiones: El estudio quimico del extracto organico de O. profundus cultivado en medio LBS permitio aislar los compuestos tirosol (1) y acetato de tirosol (2) como los responsables de la actividad IQS.","PeriodicalId":23515,"journal":{"name":"Vitae-revista De La Facultad De Quimica Farmaceutica","volume":"7 1","pages":"30-47"},"PeriodicalIF":0.0,"publicationDate":"2016-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79755664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"APOPTOTIC ACTIVITY OF ISOESPINTANOL DERIVATIVES IN HUMAN POLYMORPHONUCLEAR CELLS","authors":"M. Dadé, P. Galeano, J. Ríos, B. Rojano, G. Schinella","doi":"10.17533/UDEA.VITAE.V23N1A02","DOIUrl":"https://doi.org/10.17533/UDEA.VITAE.V23N1A02","url":null,"abstract":"Background: Inflammation is a complex physiopathologic response to different stimuli. Recently, some pharmacological strategies have been proposed that could be used for resolution of inflammation by enhancing apoptosis of inflammatory cells. Objectives: To study in vitro apoptotic activity of isoespintanol [ISO] and of two semi-synthetic derivatives, bromide isoespintanol [BrI] and demethylated isoespintanol [DMI], in human polymorphonuclear (PMN) cells. Methods: PMN were exposed to the different concentrations of ISO, BrI and DMI for 30 min in phosphate-buffered saline pH 7.4 containing 1 mg/mL glucose, 0.4 mM Mg2+, and 1.20 mM Ca2+. Viability was assessed by dimethylthiazol diphenyl tetrazolium bromide (MTT). To distinguish between the two modes of cell death, apoptosis and necrosis, we examined differences in morphological and biochemical changes of cells stained with annexin V- FITC (An) and/or propidium iodide (PI) using two different assays based on flow cytometry Results: The MTT assay revealed the ability of cells to reduce MTT salt to formazan. In the presence of BrI and DMI a significant concentration-dependent decrease of cell viability was observed. The annexin V- FITC binding assay showed a high proportion of apoptotic cells for those treated with BrI (An+/ PI-: 62.3 ± 8.2% vs. 2.1 ± 0.5% of control, P<0.05). The population of PMN treated with DMI produced the highest percentage (An+/IP+: 43.4 ± 5.2 % vs. 0.4 ± 0.3 % of control, P<0.05) of necrotic cells. Apoptotic nuclei were analyzed by PI staining. The cell population in the sub G0/G1 region represents cells with hypodiploidal DNA, an indicator of apoptosis. When cells were incubated with 50 and 100 μM of BrI, the cell population in the sub G0/G1 region increased, suggesting a dose-dependent increase in the population of apoptotic cells. The presence of the pan-inhibitor of caspases (Z-VAD-fmk) showed a significant reduction in cell population in the sub G0/G1 region, indicating less degradation of DNA. Conclusions: Bromide isoespintanol [BrI] induces an apoptotic process in PMN, mediated –at least in part– by activation of caspases, although this compound may probably act through other caspase-independent mechanisms as well.","PeriodicalId":23515,"journal":{"name":"Vitae-revista De La Facultad De Quimica Farmaceutica","volume":"34 1","pages":"11-17"},"PeriodicalIF":0.0,"publicationDate":"2016-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90301966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CONSUMER PRACTICES FOR PURCHASE, STORAGE, AND PREPARATION OF POULTRY AND EGGS IN SELECTED NORTH AND SOUTH AMERICAN COUNTRIES: A PILOT STUDY","authors":"K. Koppel, M. Sosa, Nelson Gutiérrez, Paula Cardinal, S. Godwin, S. Cates, E. Chambers","doi":"10.17533/UDEA.VITAE.V23N1A06","DOIUrl":"https://doi.org/10.17533/UDEA.VITAE.V23N1A06","url":null,"abstract":"Background: Poultry, eggs, and their products represent a potential food safety hazard. Although consumer practices related to these foods have been studied in various countries, little data exists from Latin America. Objective: The objective of this pilot study was to provide initial data to characterize consumers’ purchase, storage, handling, and preparation of poultry products and eggs in three countries: Argentina, Colombia, and USA. Methods: Consumers (n = 425 total) in each location completed a questionnaire about poultry products and egg purchase locations, storage conditions (i.e. refrigerator or freezer), preparation and handling practices, and managing leftovers. Results: The results indicated that in the USA most surveyed consumers purchased refrigerated eggs, whereas in Argentina (91%) and Colombia (84%) eggs typically were purchased at room temperature. Furthermore, almost all consumers in the USA stored eggs in the refrigerator, but 23% of Argentinian and 45.9% of Colombian consumers stored eggs at room temperature, which is potentially an unsafe practice. Some practices supported possible cross-contamination, for example washing raw eggs and poultry prior to cooking. Conclusions: These results are a first comparison across countries in the Americas of consumer poultry and egg practices and can serve as the basis for further research and development of food safety educational messages.","PeriodicalId":23515,"journal":{"name":"Vitae-revista De La Facultad De Quimica Farmaceutica","volume":"71 1","pages":"58-64"},"PeriodicalIF":0.0,"publicationDate":"2016-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83976039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CONTENT OF Hg, Cd, Pb AND As IN FISH SPECIES: A REVIEW","authors":"Julian Zuluaga Rodriguez, Sara E. Gallego Ríos, C. Botero","doi":"10.17533/UDEA.VITAE.V22N2A09","DOIUrl":"https://doi.org/10.17533/UDEA.VITAE.V22N2A09","url":null,"abstract":"Background: One of the main water contaminants are Hg, Cd, Pb and As. The chain of contamination of these metals and metalloid follows a cyclical order: Industry, atmosphere, land, water, phytoplankton, zooplankton, fish, and humans. Currently, Hg, Cd, Pb and As researches are of interest because consumption of fish with high toxic metal and metalloid concentrations affects human health. Objective: Provide information on the characteristics of Hg, Cd, Pb and As in the problematic of fishing resource contamination, their implications on human health, and international evidence on studies conducted on Caranx, Scomberomorus, Epinephelus, Euthynnus, Lutjanus, thunnus and Megalops fish genera. Methods: Database, Science Direct, Pub Med, Escopus, Springer Link, and Scopus, available information was reviewed using the keywords: Heavy metals, water pollution, fish, mercury, cadmium, lead, arsenic, health risk, regulations, biomagnification, and bioaccumulation. Results: The metals that pose the highest risks for human health are mercury, cadmium, lead, and arsenic which cause important complications in the nervous system, kidneys, bones, lungs, and cardiovascular system due to their toxicity and posible carcinogenic effect. Fish contents of Hg, Cd, Pb and As varies depending on the zone, environmental conditions, the contamination level of the fishing site, and the characteristics of the fish, being some fish more prone to accumulating higher concentrations of these metals in their muscles; among the species, the metal that showed the highest risk was mercury, being in high concentrations in the largest, most enduring predatory fish. Conclusions: Studies submitted in this review, may be used as the base for future comparisons with Hg, Cd, Pb and As concentration values in different fish studies for the Caranx, Scomberomorus, Epinephelus, Euthynnus, Lutjanus, and Megalops genera in order to be able to determine consumption recommendations and warnings.","PeriodicalId":23515,"journal":{"name":"Vitae-revista De La Facultad De Quimica Farmaceutica","volume":"56 1","pages":"148-159"},"PeriodicalIF":0.0,"publicationDate":"2015-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84877319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modification of nutritional value during storage of infant formulas elaborated with different intact and partially hydrolyzed proteins and carbohydrates","authors":"J. Contreras‐Calderón, E. Guerra-Hernández, B. García-Villanova","doi":"10.17533/UDEA.VITAE.V22N2A03","DOIUrl":"https://doi.org/10.17533/UDEA.VITAE.V22N2A03","url":null,"abstract":"Antecedentes: La leche materna es la mejor fuente nutricional para ninos recien nacidos. Sin embargo, cuando las madres no pueden proveer leche, o si los ninos son prematuros o tienen bajo peso al nacer, la lactancia debe ser reemplazada o complementada con formulas infantiles (IFs). La interaccion entre los componentes de las IFs (proteinas, grasas, carbohidratos, vitaminas y minerales) principalmente afecta carbohidratos y proteinas (Reaccion de Maillard, MR), pero los que implican proteinas son especialmente importantes en alimentacion infantil debido a los altos requerimientos de proteina de los lactantes. Por otra parte, los acidos grasos (FAs) son considerados importantes en el desarrollo de los ninos. Objetivos: El objetivo fue evaluar la estabilidad de IFs elaboradas con diferentes ingredientes, analizando lisina util (para estabilidad de proteinas), contenido de FAs y valor de peroxidos (para estabilidad de grasas) durante el almacenamiento bajo condiciones normales y adversas, y proponer un control mas rapido de la estabilidad. Metodos: Los analisis de lisina util por cromatografia liquida de alta resolucion (HPLC), oxidacion lipidica por el metodo de titulacion y el perfil de FAs por cromatografia de gases (GC) fueron determinados en cuatro tipos de IFs preparadas con proteinas intactas y parcialmente hidrolizadas con diferentes carbohidratos (lactosa y maltodextrinas) durante el almacenamiento a 4, 20 y 30 oC por 24 meses a actividad de agua normal (Aw=0,1-0,4), y a Aw de 0,65 a 20 y 30 oC por 4 semanas. Estas IFs fueron preparadas dos veces (IF1 y IF2) en baches diferentes por una empresa Espanola de productos dietarios. Resultados: A 30oC, las perdidas de lisina util fueron de 40-50% en todas las IFs analizadas. El comportamiento y porcentaje de perdidas de lisina entre la 1 y 4 semana de conservacion a 30 °C con Aw=0,65 fue similar a las obtenidas tras 24 de almacenamiento a 30 °C. No se observaron cambios significativos en el perfil de FAs durante el almacenamiento. Oxidacion solo se observo en los envases abiertos y despues de 4 semanas/30 °C/Aw=0.65. Conclusiones: Las perdidas de lisina util incrementan a mayor tiempo y temperatura de almacenamiento. Los FAs muestran una buena estabilidad para cualquiera de las condiciones de almacenamiento, sin embargo el valor de peroxidos evidencia mayor sensibilidad que los cambios en Fas para evaluar la oxidacion de las grasas durante el almacenamiento de IFs.","PeriodicalId":23515,"journal":{"name":"Vitae-revista De La Facultad De Quimica Farmaceutica","volume":"179 1","pages":"87-100"},"PeriodicalIF":0.0,"publicationDate":"2015-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88431215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physical characterization of freeze-dried foam prepared from Aloe vera gel and guar gum","authors":"V. Santacruz-Vázquez, C. Santacruz-Vázquez, Jordi Cortés","doi":"10.17533/UDEA.VITAE.V22N2A02","DOIUrl":"https://doi.org/10.17533/UDEA.VITAE.V22N2A02","url":null,"abstract":"Background: Foams are colloidal dispersions of a gas suspended in a dispersing phase, which consisting of a semi-freeze-dried or viscous liquid phase. The physical properties of food foams are the result of the bubble characteristics and their spatial arrangement. Objectives: The aim of this work was to obtain foams of A. vera gel and guar gum and describe the changes in their physical properties and microstructure during freeze-drying using the fractal dimension concept and image analysis techniques. Methods: The porosity, density, and volume expansion factor of the fresh foams that were based on the A. vera foams were determined. The kinetics of foam texture, color, porosity and microstructure of the freeze-dried foams were obtained. The fractal texture dimension of surface (FDSDBC) and microstructure (FDESEM) of the foams were determined as indicators of structural changes after freeze-drying. The guar gum concentrations used to obtain the A. vera prefoam were expressed in w/w as F1 (control simple without gum), F2 (2%), F3 (4%) and F4 (6%). Results: We obtained stable freeze-dried foams of Aloe vera gel and guar gum. The porosity, density and volume expansion factor of the fresh and freeze-dried foams were affected by the addition of the guar gum. Changes in the topology of the freeze-dried foam surface during the drying process resulted in a high rugosity compared with the original smooth surface. The microstructure of the dried foam samples suggested a relationship between the gum concentration of the prefoam A. vera gel mixture and the physical properties before and after freeze-drying, such as an increase in the microstructural alterations and surface roughness during freeze-drying. The roughness of the freeze-dried foam surface, described by the FDSDBC represented the macroscopic physical changes of the samples and correlated with the changes in the foam microstructure, which were described by the fractal dimension of the Environmental Scanning Electron Microscopy ESEM microphotographs (FDESEM). Conclusions: The digital analysis of the structure and porosity of the freeze-dried foam can be used to quantify the effect of gum concentrations on the morphological features and physical properties of foams during freeze-drying.","PeriodicalId":23515,"journal":{"name":"Vitae-revista De La Facultad De Quimica Farmaceutica","volume":"16 1","pages":"75-86"},"PeriodicalIF":0.0,"publicationDate":"2015-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85219931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ESTUDIO DEL PROCESO DE CLARIFICACIÓN DE HIDROLIZADOS DE ALMIDÓN DE YUCA UTILIZANDO MEMBRANAS CERÁMICAS","authors":"Maria Victoria Acevedo-Estupiñan, Carlos Omar Parra-Escudero, C. Muvdi-Nova","doi":"10.17533/UDEA.VITAE.V22N2A06","DOIUrl":"https://doi.org/10.17533/UDEA.VITAE.V22N2A06","url":null,"abstract":"Antecedentes: La etapa de clarificacion de hidrolizados de almidon para la produccion de jarabes de glucosa es la principal causa de su produccion por lotes, ademas de acarrear altos costos al utilizar filtros rotatorios al vacio, carbon activado y tierras diatomeas que aseguren la calidad del producto. Objetivos: Evaluar la etapa de clarificacion de hidrolizados de almidon de yuca obtenidos por via enzimatica utilizando tecnologia con membranas, a diferentes temperaturas, diametros de poro de membrana y presiones transmembrana. Metodos: La clarificacion se realizo utilizando un piloto compuesto por un tanque enchaquetado, donde se llevo a cabo la reaccion de hidrolisis. La filtracion se realizaba conectando el tanque a una bomba que permitia enviar el fluido al modulo membranario; la presion transmembrana fue fijada con una valvula a la salida del modulo. Los experimentos se llevaron a cabo usando membranas con diferentes tamanos de poro en un diseno factorial 22, evaluando dos niveles de temperatura (50 y 70oC) y dos niveles de presion transmembrana (0,15 y 0,30 MPa). Se midieron los caudales obtenidos para el retenido y el permeado. Las muestras obtenidas fueron analizadas para evaluar la calidad del permeado (turbidez, cantidad de proteina retenida, contenido de materia seca y oBrix). El analisis estadistico se llevo a cabo con el software Statgraphic Centurion XVI.I®. Resultados: Los resultados obtenidos mostraron que las presiones transmembrana (0,15 y 0,30 MPa) y temperaturas (50 y 70 oC) evaluadas no influyen significativamente sobre la permeabilidad ni calidad del permeado (p-valores > 0,05) permitiendo trabajar con la menor presion tranmembrana (menor desgaste de equipos y menor gasto energetico), y a la temperatura de hidrolisis, lo cual permitiria trabajar bajo condiciones de produccion en continuo. Ademas, se observo que es posible utilizar membranas con diametro de poro de hasta 0,8 μm; aumentado hasta en 5 veces la productividad y disminuyendo la turbidez en un 99%. Conclusiones: Es posible utilizar membranas ceramicas de microfiltracion de hasta 0,8 μm, en condiciones moderadas de presion transmembrana y a la temperatura de hidrolisis para la clarificacion de hidrolizados de almidon de yuca sin disminuir la calidad del permeado.","PeriodicalId":23515,"journal":{"name":"Vitae-revista De La Facultad De Quimica Farmaceutica","volume":"95 1","pages":"121-129"},"PeriodicalIF":0.0,"publicationDate":"2015-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83710913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physico-chemical and microbiological changes in commercial tilapia (Oreochromis niloticus) during cold storage","authors":"N. Guzman, I. Segovia, Ana López, María Ruiz Rico, J. M. B. Baviera","doi":"10.17533/UDEA.VITAE.V22N2A08","DOIUrl":"https://doi.org/10.17533/UDEA.VITAE.V22N2A08","url":null,"abstract":"Antecedentes: Los procesos microbiologicos y quimicos son los principales responsables del deterioro del pescado fresco. Por tanto, es esencial evitar estos procesos aplicando buenas practicas de fabricacion durante la manipulacion, distribucion y almacenamiento del pescado. Objetivo: El objetivo de este trabajo fue evaluar los cambios fisico-quimicos y microbiologicos en tilapia comercial (Oreochromis niloticus) duante el almacenamiento refrigerado con el fin de establecer la vida util desde su llegada al supermercado. Metodos: 27 especimenes de tilapia fueron analizados a dia 0, 2, 4 y 7 de almacenamiento a 4 oC. Se llevaron a cabo medidas de textura, color, capacidad de retencion de agua, nitrogeno basico volatil total (N-BVT), indice del acido tiobarbiturico, compuestos relacionados con el ATP, asi como analisis microbianos. Resultados: El contenido en N-BVT fue alto al principio del estudio, siendo estable durante el almacenamiento. La oxidacion lipidica de las muestras fue minima, por lo que este proceso no contribuyo al deterioro del pescado. Se observo la degradacion de inosina-5’- monofosfato (IMP) a Ino (inosina), y de Ino a Hx (hipoxantina). Los parametros de textura y color sufrieron cambios como consecuencia del deterioro del pescado. Se observaron bajos recuentos microbianos a dia 0, pero los recuentos de Enterobacteriaceae y de mesofilos aumentaron gradualmente durante el almacenamiento. Conclusiones: El valor K1 mostro el deterioro progresivo del pescado durante el almacenamiento en refrigeracion. La disminucion de dureza y firmeza confirmo la perdida de calidad a lo largo del tiempo de estudio. Los bajos recuentos microbianos al principio del estudio demostraron la buena calidad de la tilapia; sin embargo, el aumento de los recuentos de mesofilos al final del periodo estudiado mostraron que la tilapia no era adecuada para el consumo humado a dia 7.","PeriodicalId":23515,"journal":{"name":"Vitae-revista De La Facultad De Quimica Farmaceutica","volume":"96 1","pages":"140-147"},"PeriodicalIF":0.0,"publicationDate":"2015-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81096602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}